KR20190042775A - 채널병증을 야기하는 약물에 대한 DMPC, DMPG, DMPC/DMPG, LysoPG 및 LysoPC의 보호 효과 - Google Patents
채널병증을 야기하는 약물에 대한 DMPC, DMPG, DMPC/DMPG, LysoPG 및 LysoPC의 보호 효과 Download PDFInfo
- Publication number
- KR20190042775A KR20190042775A KR1020197011064A KR20197011064A KR20190042775A KR 20190042775 A KR20190042775 A KR 20190042775A KR 1020197011064 A KR1020197011064 A KR 1020197011064A KR 20197011064 A KR20197011064 A KR 20197011064A KR 20190042775 A KR20190042775 A KR 20190042775A
- Authority
- KR
- South Korea
- Prior art keywords
- dmpc
- lysophosphatidylcholine
- dmpg
- composition
- drug
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15/297,901 US10449193B2 (en) | 2011-06-03 | 2016-10-19 | Protective effect of DMPC, DMPG, DMPC/DMPG, lysoPG and lysoPC against drugs that cause channelopathies |
US15/297,901 | 2016-10-19 | ||
PCT/US2017/057446 WO2018075801A1 (en) | 2016-10-19 | 2017-10-19 | Protective effect of dmpc, dmpg, dmpc/dmpg, egpg, lysopg and lysopc against drugs that cause channelopathies |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20190042775A true KR20190042775A (ko) | 2019-04-24 |
Family
ID=62019674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020197011064A KR20190042775A (ko) | 2016-10-19 | 2017-10-19 | 채널병증을 야기하는 약물에 대한 DMPC, DMPG, DMPC/DMPG, LysoPG 및 LysoPC의 보호 효과 |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP3528848A4 (zh) |
JP (1) | JP2019531309A (zh) |
KR (1) | KR20190042775A (zh) |
CN (2) | CN109843331A (zh) |
AU (2) | AU2017345473A1 (zh) |
CA (1) | CA3039596C (zh) |
MX (1) | MX2019004222A (zh) |
WO (1) | WO2018075801A1 (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2018209164B2 (en) | 2017-01-17 | 2021-11-04 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
EP3697386B1 (en) * | 2017-10-19 | 2023-07-26 | Signpath Pharma, Inc. | Liquid compositions for peroral use comprising phosphatidylglycerol derivatives and thixotropic excipients for treating cardiac channelopathies caused by pharmacological agents |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8618847D0 (en) * | 1986-08-01 | 1986-09-10 | Smith Kline French Lab | Pharmaceutical formulations |
GB9224855D0 (en) * | 1992-11-27 | 1993-01-13 | Smithkline Beecham Plc | Pharmaceutical compositions |
UA80682C2 (en) * | 2001-08-06 | 2007-10-25 | Pharmacia Corp | Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition |
US20050233970A1 (en) * | 2004-03-23 | 2005-10-20 | Praecis Pharmaceuticals, Inc. | Methods for treating long QT syndrome |
WO2008093848A1 (ja) * | 2007-02-02 | 2008-08-07 | Sunstar Inc. | ホスファチジルコリンを含有する炎症マーカー低減組成物 |
JP5638204B2 (ja) * | 2009-05-29 | 2014-12-10 | 国立大学法人 岡山大学 | 経口投与用リポソーム製剤およびその製造方法 |
WO2012094033A1 (en) * | 2011-01-05 | 2012-07-12 | Livon Laboratories | Methods of making liposomes, liposome compositions made by the methods, and methods of using the same |
CA2836904C (en) * | 2011-06-03 | 2019-09-24 | Signpath Pharma Inc. | Liposomal mitigation of drug-induced long qt syndrome and potassium delayed-rectifier current |
WO2013121300A2 (en) * | 2012-02-16 | 2013-08-22 | Vascular Biogenics Ltd. | Methods for treating psoriasis and vascular inflammation |
CA2882978A1 (en) * | 2012-08-31 | 2014-03-06 | University Of North Texas Health Science Center | Curcumin-er, a liposomal-plga sustained release nanocurcumin for minimizing qt prolongation for cancer therapy |
JP2017516813A (ja) * | 2014-06-03 | 2017-06-22 | サインパス ファルマ, インク.Signpath Pharma, Inc. | チャネル病を引き起こす薬物に対するdmpc、dmpg、dmpc/dmpg、egpg、lysopg及びlysopcの防御効果 |
-
2017
- 2017-10-19 MX MX2019004222A patent/MX2019004222A/es unknown
- 2017-10-19 WO PCT/US2017/057446 patent/WO2018075801A1/en unknown
- 2017-10-19 EP EP17861307.1A patent/EP3528848A4/en not_active Withdrawn
- 2017-10-19 CA CA3039596A patent/CA3039596C/en active Active
- 2017-10-19 AU AU2017345473A patent/AU2017345473A1/en not_active Abandoned
- 2017-10-19 CN CN201780064810.5A patent/CN109843331A/zh active Pending
- 2017-10-19 JP JP2019518559A patent/JP2019531309A/ja active Pending
- 2017-10-19 CN CN202010289224.4A patent/CN111481508A/zh active Pending
- 2017-10-19 KR KR1020197011064A patent/KR20190042775A/ko not_active IP Right Cessation
-
2020
- 2020-11-13 AU AU2020267307A patent/AU2020267307A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN111481508A (zh) | 2020-08-04 |
CN109843331A (zh) | 2019-06-04 |
AU2020267307A1 (en) | 2020-12-10 |
AU2017345473A1 (en) | 2019-04-18 |
JP2019531309A (ja) | 2019-10-31 |
WO2018075801A1 (en) | 2018-04-26 |
CA3039596C (en) | 2022-04-12 |
EP3528848A1 (en) | 2019-08-28 |
CA3039596A1 (en) | 2018-04-26 |
EP3528848A4 (en) | 2020-07-15 |
MX2019004222A (es) | 2019-06-10 |
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Legal Events
Date | Code | Title | Description |
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A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
AMND | Amendment | ||
E601 | Decision to refuse application | ||
X091 | Application refused [patent] | ||
AMND | Amendment | ||
E902 | Notification of reason for refusal | ||
AMND | Amendment | ||
E902 | Notification of reason for refusal | ||
X601 | Decision of rejection after re-examination |