KR20190014947A - Method of preparing mixture of fertilizer agrichemical - Google Patents

Abstract

The present invention relates to a mixture composition of fertilizers and pesticides and a preparing method thereof. The mixture composition includes: a core unit including the fertilizers; a coating material coating the core unit; and a coating layer including pesticides. By integrating the fertilizers and pesticides in a single formulation for simplification, the present invention can reduce labor costs while ensuring safety.

Description

FIELD OF THE INVENTION [0001] The present invention relates to a method for preparing a fertilizer and a pesticide,

There is provided a fertilizer and an agricultural chemical mixture composition comprising a core portion including a fertilizer and a coating layer containing a covering material for coating the core portion and an agricultural chemical, and a method for producing the fertilizer agricultural chemical mixture.

Intensive agriculture, based on the use of fertilizers and synthetic pesticides, contributed to the increase in food production. However, as the population of agriculture and aging of agriculture workforce continue to increase, labor force reduction is urgently needed for the use of fertilizers and pesticides.

Recently, there have been increasing demands for technology to reduce the amount of fertilizer used, fertilization through mechanization, reduction of pesticide usage, and efficient fertilization technology. With the recent development of coating technology, there is a continuous release of fertilizer products using coating technology of fertilizer and pesticide. However, by using fertilizer and pesticide respectively, the labor force is doubled and the time for fertilization is continuously increasing. Accordingly, farmers are continuously using fertilizers and pesticides in combination. However, fertilizer and pesticide react with each other to cause harm to the crops, and problems are continuously appearing in use.

In this situation, it is expected that fertilizer and pesticide will be made into a single formulation and simplified, thereby establishing low labor input and safe use technology.

One example provides a method of making a fertilizer and a pesticide mixture, comprising coating the fertilizer with one or more selected from the group consisting of (i) insecticides and bactericides and (ii) coating.

One example provides a method of making a fertilizer and a pesticide mixture, comprising coating the fertilizer with one or more selected from the group consisting of (i) insecticides and bactericides and (ii) coating.

Each component of the coating layer may be independently coated to form a coating layer of two or more (e.g., two or three layers), or a mixture of two or more coating layers to form a single or two-layer coating layer.

In one embodiment, the method of making the fertilizer and the pesticide mixture (preparation method 1) comprises the step of mixing the fertilizer with a coating composition comprising (i) at least one selected from the group consisting of insecticides and bactericides and (ii) . The manufacturing method comprising the one-step coating step is characterized in that, prior to the one-step coating step, at least one selected from the group consisting of (i) insecticides and bactericides, and (ii) Step < / RTI >

In one example, the method of making the fertilizer and pesticide mixture

Coating a fertilizer with a coating composition containing an insecticide comprising (i-1) an insecticide and (ii) a coating, (i-2) a germicide containing a bactericide and (ii) a coating, And

Mixing the fertilizer coated with the insecticide-containing coating composition and the fertilizer coated with the bactericide-containing coating composition

. ≪ / RTI > In this case, the steps (i-1) and (i-2) may be performed simultaneously or sequentially, irrespective of the order of the steps (i-1) Or step (i-1) after step (i-2).

In another embodiment, the method for producing the fertilizer and the agricultural chemical mixture (production method 2)

(a) coating a fertilizer with a coating agent comprising at least one selected from the group consisting of an insecticide to form a insecticide mixed coating coating layer; And

(b) forming at least one coating layer selected from the group consisting of a sterilizing agent outside the insecticide mixed coating layer and

(C) forming a coating layer on the outside of the bactericide coating layer.

As described above, in consideration of the simplification of the process and reduction of the loss of the raw material, and the ease of controlling the dissolution and controlling the content of the pesticide and / or the bactericide, the method for producing the fertilizer and the agricultural chemical mixture composition comprises have.

Hereinafter, the present invention will be described in more detail.

The fertilizer used in this specification includes all natural fertilizers and synthetic fertilizers including at least one selected from the group consisting of nitrogen, phosphoric acid (P ₂ O ₅ ), potassium (K ₂ O), and magnesium (MgO) And / or complex fertilizers). The fertilizer may have a granular property to facilitate formation of a coating layer, but is not limited thereto. When the fertilizer is granular, it may have an average diameter of about 1 to about 5 mm, about 1 to about 4 mm, about 2 to about 5 mm, or about 2 to about 4 mm, but is not limited thereto. In one example, the fertilizer may include, but is not limited to, nitrogen, phosphoric acid, and potassium in a weight ratio of, for example, 30: 6: 6.

The pesticide used in the present specification may include one or more pesticides selected from the group consisting of pesticides and bactericides, and one or more pesticides and / or one or more bactericides. The insecticide may be at least one selected from among all insecticides capable of controlling the desired insect pests of the applied crop, and the insecticide may be at least one selected from all the disinfectants capable of controlling the desired pathogens of the applied crop. The insecticide and / or bactericide may be appropriately selected in consideration of the type of applied crop, the type of insect pests and / or pathogens to be controlled, the dissolution profile (elution rate in lag time and release time), water solubility, soil half life, For example, for application to rice, the insecticide may be selected from the group consisting of carbosulfan, fipronil, chlothianidine, carbofuran, benfuracarb, thiamethoxam, thiacloprid, dinotefuran, cloranthraniliprol, Imidacloprid, and the like; for example, at least one member selected from the group consisting of carbosulfan, fipronil, chlothianidine, and carbofuran; The fungicide may be selected from the group consisting of a fungicide for pyrogenic fungi including probenazole, thiadinyl, isoprothiollane and acibenzolla-s-methyl, a fungicide for sheath blight fungi including thifluzamide, Systorobin, etc., and a fungicide of a sheath blight fungus. Examples of the fungicide include 1, 2, 3, 4, 5 or 6 members selected from the group consisting of probenazole, orisastrobin, thiadinyl, and azoxystrobin May be more than species; But is not limited thereto.

The coating agent used in the present invention may include at least one member selected from the group consisting of all the coating polymers used for covering the fertilizer. In one example, the covering may be an olefin resin, and the olefin resin may be polyethylene, ethylene vinyl acetate (e.g., having a vinyl acetate content of 10 to 25% by weight or 15 to 20% by weight), polypropylene, 4-methylpentene and the like, and olefin-based block copolymers, but the present invention is not limited thereto. In one example, the coating agent may be at least one olefin-based polymer selected from the group consisting of polyethylene, polypropylene, poly-4-methylpentene and the like, ethylene vinyl acetate, and the like. May include.

The coating agent may further include at least one selected from the group consisting of an organic material and an inorganic material in addition to the coating polymer. The organic material may be at least one selected from biodegradable natural or synthetic biodegradable natural or synthetic organic materials such as polylactic acid (PLA), polyhydroxyalkanotate (PHA), poly (butylene succinate), polycaprolactone (PCL) And natural decomposition initiators. The inorganic substances may be at least one selected from water-insoluble inorganic substances, for example, selected from the group consisting of talc, bentonite, loess, diatomaceous earth and carbon But it is not limited thereto.

Wherein the coating agent comprises 30 to 80 parts by weight of an olefin resin; 1 to 30 parts by weight of a biodegradable organic material; And the water-insoluble inorganic material may include 10 to 70 parts by weight. As used herein, the term " part by weight " is intended to indicate the content of each component to the weight ratio between components.

In one example, the coating layer (or coating composition)

1 to 20% by weight of at least one selected from the group consisting of insecticides and bactericides;

40 to 55% by weight of an olefin resin;

From 30 to 45% by weight or from 35 to 40% by weight of a water-insoluble inorganic material; And

1 to 20% by weight or 5 to 15% by weight of biodegradable organic materials,

. ≪ / RTI >

The coating may be performed at a temperature of from about 50 DEG C to about 80 DEG C, from about 50 DEG C to about 70 DEG C, from about 60 DEG C to about 80 DEG C, or from about 60 DEG C to about 70 DEG C for a period of from about 10 minutes to about 90 minutes have.

(Ii) at least one selected from the group consisting of (i) an insecticide and a bactericide and (ii) a content of a coating layer (solid content) containing the coating agent, in the fertilizer and the agricultural chemical mixture composition provided herein, (Coating rate) is 1 to 30% by weight, 1 to 25% by weight, 1 to 20% by weight, 3 to 30% by weight, 3 to 25% by weight, 3 to 20% by weight , 5 to 30 wt%, 5 to 25 wt%, 5 to 20 wt%, 9 to 30 wt%, 9 to 25 wt%, or 9 to 20 wt%.

In one example, the content of at least one selected from the group consisting of insecticides and bactericides contained in the fertilizer and pesticide mixture composition is 0.01 to 10 wt%, 0.01 to 5 wt%, 0.01 to 1 wt%, or 0.01 to 0.5 wt% .

Plants to which the fertilizer and pesticide blend composition provided herein can be applied include plants (e.g., horticultural plants, field cultivated plants, etc.) cultivated in a dry environment (e.g., fields, gardens, pollen, etc.), submerged or freshwater cultivated crops , Rice plants, etc.), hydroponic cultivated crops, and all terminal and dicot plants consisting of aquatic plants, or all herbaceous and woody plants.

In one example, the plant is a food crop including rice, wheat, barley, corn, soybean, potato, wheat, red bean, oats and millet; Vegetable crops including Arabidopsis, cabbage, radish, pepper, strawberry, tomato, watermelon, cucumber, cabbage, melon, squash, onions, onions and carrots; Special crops including ginseng, tobacco, cotton, forage, grass, sesame, sugar cane, beet, perilla, peanut, rapeseed, grass and castor; Apple trees, pears, jujubes, peaches, sheep, grapes, citrus, persimmon, plums, apricots and banana; Wood flour including pine, palm oil and eucalyptus; Roses, gladiolus, gerberas, carnations, chrysanthemums, lilies and tulips; And feed crops including raglass, red clover, orchardgrass, alfalfa, tall fescue and perennialla grass, but are not limited thereto. As a specific example, the plant may be selected from the group consisting of Arabidopsis, potato, eggplant, cigarette, pepper, tomato, burdock, chard kiss, lettuce, bellflower, spinach, modern sweet potato, celery, carrot, buttercup, parsley, cabbage, , Dicotyledonous plants such as cucumber, amber, pak, strawberry, soybean, mung bean, kidney bean, or pea; And monocotyledons such as wheat, barley, corn, sorghum, and the like. However, the present invention is not limited thereto.

The plant application method of the fertilizer and the agricultural chemical mixture composition provided herein is not particularly limited and can be applied by a conventional method. For example, when applied to rice, the fertilizer and pesticide mixture composition may be treated in a seeding box when sowing rice, or seeded on a sowing plant using an automatic seeder, then sowing and nursing rice seedlings, Can be processed. In another example, the fertilizer and pesticide mixture composition may be applied to the seedling pots of the crops immediately prior to transplanting the seedlings, or seeded or planted in the pots or pots at the time of sowing of rice or field crops.

As described above, the method for producing a fertilizer pesticide blend according to the present invention is characterized in that the fertilizer and the pesticide are mixed with the coating agent or coated, or the coating agent is coated after coating the coating agent, It is possible to manufacture a product with excellent labor saving effect by minimizing the loss of fertilizer and pesticide by minimizing the loss of fertilizer and pesticide by containing fertilizer and pesticide in a single formulation and minimizing labor input for agricultural work at fertilization. In addition, by containing pesticides in the coating agent, it is possible to avoid direct contact, thereby improving the safety of pesticide use.

Figure 1 schematically shows the coating concept of a fertilizer / pesticide blend composition.
Fig. 2 schematically shows a pretreatment process for analyzing the pesticide content in the fertilizer / pesticide mixture composition.
FIG. 3 is a graph showing the dissolution rate in water according to a fertilizer / pesticide mixed formulation containing an insecticide candidate candidate substance according to an embodiment.
FIG. 4 is a graph showing the dissolution rate in water according to a fertilizer / pesticide mixed formulation containing a disinfectant agent candidate material according to one embodiment. FIG.
FIG. 5 is a photograph showing a granular fertilizer / agricultural chemical mixture (sanitizer + insecticide) mixed coating formulation according to one embodiment.
FIG. 6 is a photograph showing the growth after 25 days of sowing rice cultivation of a rice cultivar treated with a fertilizer / agricultural chemical mixed coating formulation according to one embodiment.
7 is a photograph showing a matt section of a chrysanthemum base plate treated with a fertilizer / agricultural chemical mixed coating formulation according to one embodiment after 15 days of sowing.
Figure 8 is a photograph showing the efficacy (control effect) of the chlorothianidine + orisastrobin formulation on the insecticide / insecticide composition according to the insecticide / fungicide composition.
FIG. 9 is a photograph showing the drug efficacy (control effect) on the offspring according to the pesticide / fungicide composition of the chlorothianidine + provenazole formulation.

Hereinafter, the present invention will be described in detail by way of examples. However, the following examples are illustrative of the present invention, and the present invention is not limited by the following examples.

Example  1: fertilizer / pesticide In a mixture  Selection of suitable pesticide (disinfectant / insecticide) to use

In case of insecticide and fungicide, it is used for the mixture of fertilizer and pesticide based on water solubility, soil half-life, target pest control spectrum etc. As a fungicide and insecticide, seven kinds of pesticides and four kinds of bactericides were finally selected as candidates.

Specifically, the raw material having a water solubility of more than 400 ppm of the raw material acts as a release trigger that bursts in the water when used in the seeding phase, so that it is not easy to control the dissolution of the fertilizer component when applied as a constituent of the coating, It is difficult to select an original material having a water solubility of 400 ppm or less. Also, in order to secure the stability and efficacy of the pesticide in the soil, the pesticide having a soil half-life of at least 30 days was selected. Exceptionally, Tiadinil has a very short half-life of 3 to 5 days. However, commercially available seed treatment agents are high in cost and relatively low in price, so they are included in the candidate product. Azoxystrobin also has a half-life of about 2 weeks Because it is possible to control simultaneously with blast foliage and sheath blight disease, it is included in candidate candidate.

 On the basis of the above criteria, finally, three kinds of insecticides, namely Carbosulfan, Fipronil, and Clothianidin, and four fungicides, namely, azoxystrobin, pro A total of seven starting materials were selected for the following tests: probenazole, thiadinyl, and orysastrobin.

The properties of the selected medicament are summarized in Table 1:

Target pest Drug name Water solubility Soil half-life Pesticide
Water weevil
Insect pest Cabo Sulpano 3 ppm 3 to 30 days (in soil) Fipronil 2 ppm - Chlorothianine 300ppm 148 ~ 1,155 days
(Soil aerobic) disinfectant Blast Provenazole 150ppm 24h (in soil) Thiadinyl 13 ppm 3 to 5 days (in paddy) Blindfold / sheep pattern
blight Orissa Strobin 81 ppm 51 ~ 58 days (Field)
More than 365 days (Lab) Azi Sistrovin 6 ppm 14th (Field)

Example  2: Preparation of one-pot coating composition according to the candidate agent and measurement of yield after coating

In order to prepare a one-pot coating composition for coating the fertilizer / pesticide mixture, the pesticide (insecticide or fungicide) raw material and the coating material are quantified as shown in Table 4 below, And toluene were heated at 30 to 100 占 폚 in accordance with the volatility characteristics to dissolve and disperse them, thereby preparing seven types of coating compositions for each prescription.

A one-pot coating was applied to each of the above-prepared coating compositions using a fluidized bed coater so that the fertilizer (nitrogen-phosphoric acid-potassium: 30-6-6) A pesticide or a bactericide) and a coating polymer comprising a coating polymer.

The coating conditions were as follows:

Hot air volume: 8 ~ 9m / sec

Hot air temperature: 60 ~ 70 ℃

Fertilizer particles: 2 ~ 4㎜

Fertilizer input: 1.5㎏

Coating composition concentration: 5 to 20% solids content

Coating composition feed rate: 1-5 g / min

Coating time: 17 ~ 68 minutes

Coating ratio: 5 to 20 wt%

The analysis of the crude content in the prepared fertilizer / pesticide mixed coating formulation for each prescription was carried out by extracting the film-forming raw material using THF (tetrahydrofuran) extraction method, which is a method of analyzing the content of pesticide in the new fertilizer / agricultural chemical mixture, Analysis.

The pretreatment process of the HPLC analysis including the THF extraction method is schematically shown in FIG.

HPLC analysis was performed under the conditions of Table 2 below:

division Analysis condition Column Capcellpack MG-II C18 (25 cm x 4.6 mm, 5 m) Mobile phase Acetonitrile: DW = 50: 50, (pH 3 by H ₃ PO ₄ ) Flow rate 1.0 ml / min Wavelength 254 nm Column Temp. 40 ℃ Injection volume 10.0 [mu] l Internal
standard Dimethyl Phthalate (DMP) / Acetonitrile (ACN)
= 5 g / l Run time 15 min

The analytical methods of FIG. 2 and Table 2 were verified through repeated analysis of the fertilizer / pesticide mixed coating formulations obtained using the coating composition comprising chlothianidine or oresastrobin, and the results are shown in Table 3:

division Orissa Strobin Chlorothianine The amount of the raw material (wt.%) 1.033 2.750 Analyzed raw material content (% by weight) 1.013 2.729 (% By weight) 98.1 99.2%

As shown in Table 3, since the yield of the raw material after coating was analyzed to be about 98% or more, the raw material analysis method of the fertilizer pesticide mixture was finally confirmed.

Therefore, it can be confirmed that the crude content analysis method of FIGS. 2 and 2 can accurately analyze the crude content in the coating.

Using the above-described raw material content analysis method, the coating yield and the content of the raw material at the time of one-pot coating were measured with seven kinds of coating compositions, and they are shown in Table 4 below.

The composition of the seven coating compositions and the raw coating yield and the original content Type of raw material Ratio of coating material (% by weight) Raw coating yield
(weight%) Raw material content
(weight%) Polymer A Polymer B Minerals Organic matter The corresponding original Pesticide Cabo Sulpano 18.0 27.0 37.9 3.0 14.1 96.7 2.405 Fipronil 22.8 22.8 38.3 12.8 3.3 82.9 0.423 Chlorothianine 22.9 22.9 38.5 12.8 2.8 88.3 0.376 disinfectant Provenazole 32.5 11.4 36.9 11.4 7.8 85.5 0.928 Orissa Strobin 32.5 11.4 36.9 11.4 7.8 98.1 1.013 Azi Sistrovin 32.5 11.4 36.9 11.4 7.8 94.9 1.030 Thiadinyl 29.7 10.4 33.7 10.4 15.7 93.3 2.202

 (Polymer A: polyethylene,

Polymer B: ethylene vinyl acetate,

Minerals: talc,

Organics: starch,

Raw coating yield (%) = raw material content / original amount x 100)

In case of insecticide-containing fertilizer / pesticide mixed formulation, the efficacy should be fermented up to about 60 days after transplanting, and the release of fertilizer should be less than 5% by weight before and after 20 days before seeding. Therefore, in order to control the elution of the base material up to 60 days, a coating composition containing 12 wt% or more of organic matter and a ratio of polymer A and B of 1: 1 by weight was selected and coated. As shown in Table 4, the yields of coating raw materials were 82.9% and 88.3% in the case of fipronil and chlorothianidine, respectively, but 96.7% in case of carbosulfan. This is considered to be the result that the carbosulfanic anhydride is completely dissolved in a highly viscous liquid or coating solvent and adheres well to the surface of the fertilizer when coated by the primer stickiness.

In the case of a fertilizer-containing fertilizer / pesticide mixed coating formulation, the effect of the raw material should be maintained continuously for about 50 to 90 days after the sickling occurs (about 50 to 75 days after transplanting in case of blast disease, ~ 90 days). Therefore, the coating composition was designed so that the organic matter content was less than 12% by weight and the ratio of the polymer A and the polymer B was 3: 1 by weight in order to control the dissolution period of the raw material from the transition period to the whole growth of rice. As shown in Table 4, in the case of oresastrobin, azoxystrobin, and thiadinyl, the yields of the original coatings were 98.1%, 94.9% and 93.3%, respectively. This suggests that the coating and solvent solubility of orisastrobin, azoxystrobin, and thiadinyl in the coating solvent is increased, resulting in increased coating yield. In the case of provenazole, the original coating yield was 85.5%, which was lower than those of the three candidate fungicides. In the case of provenazole, the dispersion degree and the tackiness of the original coating agent are low, and the yield is relatively low. However, it is not insufficient to be included in the coating composition.

Example 3. Fertilizer / Pesticide Elution Analysis of Fertilizer / Pesticide Mixed Coating Formulation

One-pot coatings on seven candidate compounds (three insecticides: carbosulfan, fipronil, clothianidine; four fungicides: azoxystrobin, provenazole, thiadinyl, orisastrobin) And the dissolution rate of the fertilizer in water was analyzed after the fertilizer / pesticide mixed coating formulation was prepared. The fertilizer / pesticide mixed coating formulation was prepared by coating a 30-6-6 (nitrogen-phosphoric-potassium component ratio) fertilizer with a coating composition having the composition shown in Table 4.

The fertilizer / pesticide mixed coating formulation prepared for each composition was subjected to a water elution test at 25 ° C in a thermostat. Samples were collected every 10 days and analyzed by nitrogen using a Kjeldahl 8400 analyzer (Foss, Kjeltec Auto 8400 Analyzer) Respectively.

The results are shown in Fig. 3 (result of mixed coating formulation coated with insecticide-containing coating composition) and Fig. 4 (result of mixed coating formulation coated with bactericide-containing coating composition), respectively.

As shown in FIG. 3, in the case of the carbosulfate-containing formulation, the lag time elution was about 9.2%, and the elution control at the level of 5% or less, which can secure seedling stability, was not achieved. At 65% level, the rate of fertilizer dissolution may be somewhat lower during the period when the fertilizer is needed during the rice growing season.

In the case of the carbosulfate-containing formulation, the elution time of the lag time was about 5%, and the seedling stability was expected, and the release time of the fertilizer was about 75%.

In the case of chlorothianine-containing formulations, the elution time of the lag time is about 2.7%, and the stability during the seedling period is very high. The release time of the fertilizer is also 85% or more over 90 days, .

As shown in FIG. 4, the dissolution rate of lag time was less than 5% in the case of three kinds of fungicides, thiadinyl, orisastrobin, and provenazole, It was confirmed that fertilizer efficiency can be maximized during the growth period of rice at 85% level. In the case of astaxanthin, the elution time of lag time was rather high at 14.8% level, indicating that it may be difficult to secure seedling stability.

Example 4. Selection of combination of fertilizer / pesticide mixed coating formulation

As in Example 3, seven antibiotics (three insecticides: carbosulfan, fipronil, clothianidine, four fungicides: azoxystrobin, provenazole, thiadinyl, orisastrobin) The coating formulations obtained by coating each with the One-pot concept were mixed with the pesticide (insecticide + fungicide) combination shown in Table 5 to prepare a fertilizer / pesticide mixed formulation:

Fertilizer / Pesticide Mixture Coating Formulation Combination Candidate composition (12 species) Fertilizer component
(NPK) Throughput
(g / base plate) (% By weight) Pesticide disinfectant Fipronil + azoxystrobin 30-6-6 600 0.05 0.29 Fipronil + orisastrobin 0.05 0.29 Fipronil + provenazole 0.05 0.30 Fipronyl + thiadinyl 0.05 0.50 Carbosulfan + azoxystrobin 0.29 0.29 Cabo Sulp + Orissa Strobin 0.29 0.29 Carbosulfan + provenazole 0.29 0.30 Carbosulfan + thiadinyl 0.29 0.50 Chlorothianine + azoxystrobin 0.04 0.29 Clothianidine + Orissa strobin 0.04 0.29 Clothianidine + Probenazole 0.04 0.30 Chlothianidine + thiadinyl 0.04 0.50

(The amount of the raw material is based on the total weight of the total fertilizer / pesticide mixed coating formulation)

As shown in Table 5, fertilizer / pesticide mixed coating formulations were prepared for each candidate combination by using fertilizer (30-6-6), and 600 g per papermaking seedlings were seeded in a commercially available seedling and seedling- Pesticide-added products (Combine (Palm Hanon), Hansone (Seongbo Chemical Co., Ltd.), etc.).

FIG. 5 shows the obtained fertilizer / pesticide mixed type fertilizer according to each combination. As shown in FIG. 5, in the case of the fertilizer / pesticide mixed coating formulation, it has various colors depending on the original color of the combined raw materials, and the average particle diameter is in the range of 1 to 5 mm.

Example 5: Hair growth stability test of fertilizer / pesticide mixed formulation

In order to verify the seedling stability of the 12 fertilizer / pesticide mixed coating formulations prepared in Example 4, seeding and seedling cultivation were carried out under the following conditions:

- Varieties: Chungcheong

- Seed amount: 200g / pattern

- Root: Lower Root / upper Root All of Hanwon Supermarket

- Fertilizer: Mixed fertilizer / pesticide formulation 600g / base plate (see Table 5 for the content of base)

- Box building: 3 days box build in 30 ℃ constant temperature / hygrostat

- Nursery Place and Denture Method: Test Bed in Glasshouse

- Water management: Watering more than 3 times / day

- Growth Investigation: 10 days, 20 days, and 25 days after sowing, plant height, leaf color (chlorophyll content value: SPAD-520plus, KONICA MINOLTA)

15 days Mat survey (visual observation)

The test was conducted under the seeding and nursery test conditions described above, and the change was observed with daily visual observation.

The results are shown in Table 6 and FIG. 6 (25DAS).

Test group 10 DAS 20 DAS Length (cm) Length (cm) Leaf color Practice 14.5 a b 17.6 b 25.9 b Madison 13.2 b 21.5 ab 28.5 ab Carbosulfan + azoxystrobin 14.0 a b Than Than Cabo Sulp + Orissa Strobin 15.2 a Than Than Carbosulfan + provenazole 15.3 a Than Than Carbosulfan + thiadinyl 14.5 a b Than Than Chlorothianine + azoxystrobin 14.3 ab Than Than Clothianidine + Orissa strobin 14.0 a b 22.3 ab 30.1 a Clothianidine + Probenazole 14.7 ab 22.7 ab 27.2 ab Chlothianidine + thiadinyl 14.8 ab 22.7 ab 29.7 a Carbosulfan + azoxystrobin 14.0 a b Than Than Cabo Sulp + Orissa Strobin 15.3 a 23.7 a 28.8 ab Carbosulfan + provenazole 15.5 a Weak compared Weak compared Carbosulfan + thiadinyl 15.2 a 22.3 ab 29.6 a

As shown in Table 6 and FIG. 6, normal growth was observed in all of the 12 species treatment groups until 10 DAS after seeding as a result of seedling stability test. From 20 DAS, Symptoms began to develop in both sulphate and azoxystrobin-containing formulations. Especially, in case of carbosulfan - containing group, visual observation revealed that the symptoms appeared from about 18 DAS compared with the middle part of the plate. On the other hand, seedling stability was confirmed in the case of carbosulfan and azoxystrobin - free groups. On the other hand, carbosulfan, which is an insecticide, has a disadvantage in that the yield of the raw material is relatively low at 82% and the water solubility is also relatively low at 2 ppm at the time of formulation. In the case of thiadinyl as a disinfectant, It is expected that there will be disadvantages such as clogging of nozzle and increase of operating time during coating.

In the case of mixed seeding and fertilizer / pesticide mixed fertilizer, fertilizer was located at the bottom of roots. Therefore, at 20 DAS, 3 ~ 5 cm was higher in plant height than in general planting seedlings and 3 ~ 4 higher in SPAD value. In the case of 25 DAS, the mortality rate of the seedlings was higher than that of the carbosulfan and azoxystrobin treated groups, especially the carbosulfan + azoxystrobin treated groups.

The cause of the symptoms as compared with the raw materials is one of the coating compositions of the fertilizer / pesticide mixed coating formulation, and the pesticide raw material is contained in the coating composition of the fertilizer / pesticide mixed coating formulation. Thus, the physical and chemical properties, such as solubility in water, physical properties (liquid phase, It is considered that the elution of the fertilizer component during the seedling growing period can not be controlled due to the coating efficiency. The evidence suggests that the symptom appears as compared with the fast-dissolving formulations of seed-containing formulations.

In the mat state, at 15 DAS, it was confirmed that the mat formation was comparable to the practice in all of the test groups when visually confirmed. As can be seen from the cross sectional photograph of FIG. 7, the fertilizer / However, it was confirmed that the seedlings were safely cultivated due to the special fertilizer dissolution pattern of sigmoid.

Among the 12 candidate formulations, it was found that the dissolution rate of the fertilizer and seedling stability were secured, the coating yield was high at the time of formulation, and the amount of the raw material was small, and the amounts of chlorantidin + orisastrobin and chlorothianidine + Two types including sol were selected as the final formulation.

Example 6. Selection of raw material content of fertilizer / pesticide mixed coating formulation

In order to determine the appropriate raw material content of the two fertilizer / pesticide mixed coating formulations selected in Example 5 above, the pot was subjected to pot test.

A fertilizer / pesticide mixed coating formulation was prepared with the composition of Table 7 below:

Formulation Pesticide composition
(%: weight%) Fertilizer component
(NPK) Throughput
(g / base plate) (% By weight) Pesticide disinfectant Formulation 1 Chlothianidine (0.024%) +
Orissa Strobin (0.174%) 30-6-6 600 0.024 0.174 Clothianidine (0.032%) +
Orissa Strobin (0.232%) 0.032 0.232 Clothianidine (0.041%) +
Orissa Strobin (0.29%) 0.041 0.29 Formulation 2 Chlothianidine (0.024%) +
Probenazole (0.18%) 0.024 0.18 Clothianidine (0.032%) +
Probenazole (0.24%) 0.032 0.24 Clothianidine (0.041%) +
Probenazole (0.30%) 0.041 0.30

(The amount of the raw material is based on the total weight of the total fertilizer / pesticide mixed coating formulation)

The seeds were fertilized with 200 g / seedlings and fertilized at a rate of 600 g / m3. The seeds were seeded at 3 g / m 3 in a constant temperature / And the seedlings were carried out. On the 20th day after planting, the seedlings were cultivated in a greenhouse after 6 weeks of transplanting.

On the 30th day after the transplantation, a cylindrical glass case was attached to each port and more than 50 mice were inoculated, and the live embryo was measured on the 1st, 4th and 6th day.

The results of the evaluation of the efficacy of the herbicide of Formulation 1 (chlorothianidine + orisastrobin) (control efficacy; insecticide ratio) are shown in Table 8 and FIG. 8:

 Formulation 1 (chlorothianidine + orisastrobin) Test group Control (%) 1 DAT 4 DAT 6 DAT Seagrass (unrestricted) [106.4] ^* [119.0] ^* [143.2] ^* Chlothianidine (0.024%) +
Orissa Strobin (0.174%) 9.1 b 35.8 b 63.0 b Clothianidine (0.032%) +
Orissa Strobin (0.232%) 15.8 ab 53.6 a 89.8 a Clothianidine (0.041%) +
Orissa Strobin (0.29%) 18.7 a 58.8 a 90.9 a

(DAT: Day after Transplanting;

*: Percentage of live insects (not live insect survivors)

As shown in Table 8 and FIG. 8, a comparatively low control value of 60% in the case of chlorothianidine (0.024% (on a weight basis, the same is the same)) + orisastrobin (0.174% (0.032%) + orisastrobin (0.232%) and chlorothianidine (0.041%) + orisastrobin (0.29%) were approximately 90% on the 6th day after inoculation Of the control. In particular, in the case of chlothianidine (0.032%) + orisastrobin (0.232%) formulation, chlorantidin (0.041%) + orisastrobin with higher raw material content and the same raw material content as marketed product (0.29%) formulation, it is anticipated that the effect of reducing the amount of raw materials will be effective. Therefore, in the case of Formulation 1, the final content of clotidine was determined to be 0.032% by weight and the content of orisastrobin to be determined to be 0.232% by weight.

The results of the pharmacological evaluation test for the herbicide of Formulation 2 (clotidine and provenazole) are shown in Table 9 and FIG. 9:

Formulation 2 (chlorothianidine + provenazole) The results of the control Test group Control (%) 1 DAT 4 DAT 6 DAT Seagrass (unrestricted) [107.2] ^* [124.0] ^* [161.2] ^* Chlothianidine (0.024%) +
Probenazole (0.18%) 3.1 b 26.3 c 57.4 c Clothianidine (0.032%) +
Orissa Strobin (0.24%) 15.2 ab 45.1 b 82.9 b Clothianidine (0.041%) +
Orissa Strobin (0.30%) 21.0 a 60.2 a 91.4 a

(DAT: Day after Transplanting;

*: Percentage of live insects (not live insect survivors)

As shown in Table 9 and FIG. 9, the chlorantidin (0.032%) + probenazole (0.18%) treatment group showed a relatively low control value of less than 60% (0.041%) + probenazole (0.3%) in the group treated with probenazole (0.24%) in the treatment group, and more than 83% in the control group after 6 days after inoculation It was confirmed that the control efficacy was about 90% or higher in the car on the 6th day. Particularly, in the case of the group treated with chlorantidin (0.041%) + provenazole (0.3%), the control as the standard for registration of insecticide satisfies the level of 90% or more, By weight, and the content of provenazole was determined to be 0.3% by weight.

Claims (6)

A method for producing a fertilizer and an agricultural chemical mixture, comprising coating a fertilizer with a coating composition comprising (i) at least one selected from the group consisting of an insecticide and a bactericide, and (ii) a coating. The method according to claim 1, wherein the fertilizer is in granular form having an average diameter of 1 to 5 mm. The method according to claim 1, wherein the coating comprises an olefin resin, a biodegradable organic material, and a water-insoluble inorganic material. 4. The method according to claim 3, wherein the coating comprises 30 to 80 parts by weight of an olefin resin; 1 to 30 parts by weight of a biodegradable organic material; And 10 to 70 parts by weight of a water-insoluble inorganic material. 5. The method according to any one of claims 1 to 4, wherein the coating is performed in a one-step process. 5. The method according to any one of claims 1 to 4, wherein the coating is carried out at 50 to 80 DEG C for 10 to 90 minutes.

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