KR20190014008A - Improvement Of Acne Treatment Using Natural Extract - Google Patents

Improvement Of Acne Treatment Using Natural Extract Download PDF

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KR20190014008A
KR20190014008A KR1020190006809A KR20190006809A KR20190014008A KR 20190014008 A KR20190014008 A KR 20190014008A KR 1020190006809 A KR1020190006809 A KR 1020190006809A KR 20190006809 A KR20190006809 A KR 20190006809A KR 20190014008 A KR20190014008 A KR 20190014008A
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extract
container
solution
acne
ball
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KR1020190006809A
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Korean (ko)
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윤슬기
신예진
김민홍
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윤슬기
김민홍
신예진
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
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  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to the production of an acne treatment agent using a natural extract, in which chemical components are excluded by a method of solutionizing a natural herbal extract and putting the same in a ball container. The acne treatment agent comprises: a ball which comes into contact with a skin and a solution comes out therefrom; a coupling part for coupling the ball and a body of the container; a body part of the container containing the extract and is for protecting the extract solution; a solution part which is an antibacterial liquid-type extract treatment agent; and a lid for preventing bacterial contamination of the container and preventing evaporation of the solution. The present invention has an antibacterial effect on various causative bacteria of skin diseases, thereby being able to treat various skin diseases.

Description

천연 추출물을 이용한 여드름 치료제 개발{Improvement Of Acne Treatment Using Natural Extract}≪ Desc / Clms Page number 2 > Improvement of Acne Treatment Using Natural Extract

본 발명은 여드름균에 대한 항균성 성질이 함유된 약초 천연 추출물(고삼, 마치현, 어성초)을 용액화 하여 볼용기에 담아내는 형식으로 화학성분을 배제하여 천연성분을 이용한 여드름치료제 제작에 관한 것이다.The present invention relates to the preparation of a therapeutic agent for acne using natural ingredients by excluding chemical components in the form of being dissolved in a ball container by dissolving natural herbal extracts (gosam, mashinjia, orchid) containing antimicrobial properties against acne bacteria.

일반적으로 여드름은 다양한 원인이 복합적으로 작용하여 발생한다. 주로 사춘기에 접어들면서 남성 호르몬 작용을 하는 안드로겐의 분비가 급격하게 증가하여 생기는데, 피지선이 활성화되면서 피지가 과다하게 분비되고 피부의 각질이 탈락되지 못하고 두껍게 쌓이는 것이 주요한 원인이다. 두껍게 쌓인 각질 세포들이 모낭 입구를 막아 피지가 모낭에 쌓이게 되면 여드름의 특징인 면포(모낭 속에 고여 딱딱해진 피지)가 생기게 된다. 여기에 세균이 증식하게 되면 염증이 발생하여 붉게 부어오르고 고름이 차거나 염증이 단단하게 덩어리져서 피부 깊숙이 파고든 형태의 병변이 나타난다. 여드름의 치료에는 여러 가지 약물들이 있으나 어느 한 가지만 사용하기보다는 2~3가지의 외용제(피부질환이 있는 부위에만 국소적으로 바르는 약)를 함께 사용하거나 외용 복합제 혹은 외용제와 경구제(먹는 약)를 함께 사용하는 것이 치료 효과를 높일 수 있다. 하지만 이러한 여드름 약들은 화학성분을 다량 함유하고있어 다양한 부작용이 발생하고, 건강을 오히려 해칠 뿐만아니라 내성세균과 같은 2차 감염을 유발하기도 하는 문제점이 있다.Generally, acne is caused by a combination of various causes. The main cause is the accumulation of androgens acting as a male hormone, which is mainly in puberty, and sebaceous glands are activated and excess sebum is secreted and the skin is not removed. When the thick keratinocytes block the entrance of the hair follicles and sebum accumulates in the hair follicles, the skin becomes a feature of acne (sebaceous follicles in the hair follicle). When the bacterium proliferates, it becomes inflamed and swollen red, and the pus or the inflammation is firmly clumped, and the lesion appears in the form of digging deep into the skin. There are various drugs for the treatment of acne, but rather than using only one, two or three external preparations (drugs that are applied locally to the site of the skin disease), or a combination of external and external drugs and oral drugs Use together can increase the therapeutic effect. However, these acne medicines contain a large amount of chemical components, so that various side effects occur, which not only hurts health but also causes secondary infections such as resistant bacteria.

본 발명의 목적은 여드름은 우리 주변에서 가장 흔하게 앓고 있는 피부질환의 하나로써 완벽한 치료가 어렵고 현재로써 효과적인 방법은 화학의약품과 피부과 시술이 전부이다. 여드름을 유발하는 원인은 한 가지가 아닌 복합적인 이유로 나타날 때가 많다. 화장품의 여러 화학 성분이 여드름 발생의 원인이 될 수 있음은 잘 알려진 바다. 또한 포마드 중에 포함된 유성물질이나 과도한 세제, 비누의 사용도 여드름의 악화 원인이 될 수 있다. 그 중에서도 특히 여드름 원인 균은 지방 분해 효소를 분비하여 이 효소가 피지 중의 중성지방을 분해하여 유리 지방산을 형성하고 모낭을 자극한다. 또한 여드름 원인 균에 대한 면역학적 반응이 여드름의 염증 반응에 기여한다. 즉 여드름을 일으키는 원인은 다양하지만 주된 원인으로 여드름 원인 균을 꼽을 수 있다. 따라서 항균효과가 뛰어나며, 가려움증, 피부 화농성을 치료하는데 탁월한 고삼과 항균효과, 독소배출, 여드름 및 아토피 등의 피부질환에 효과적이며, 트러블을 완화시키고 가려움증 통증, 무좀과 습진 치료에도 효과적인 마치현, 마지막으로 시중에 여드름 비누 등에 많이 이용되어 여드름 치료에 효과가 있다고 잘 알려져 있는 어성초, 이러한 세 가지의 약초 추출물을 이용하여 다양한 부작용과 비효율성을 고려하여 화학성분이 배제된 천연추출물로의 여드름 치료제 개발의 연구를 진행하였다. 이 연구로 화학의약품만이 항균효과에 뛰어나 여드름 질환의 치료가 가능하다는 선입견을 깨고, 피부에 적합하고 부작용이 없는 치료제를 얻고자 한다.The object of the present invention is that acne is one of the most common skin diseases around us, and therefore, it is difficult to completely cure it, and at present, chemical medicines and dermatology are all effective methods. The cause of acne is not one thing but a complex cause. It is well known that many chemical components of cosmetics can cause acne. Also, the use of oily substances, excess detergent, and soap contained in the pomade may cause deterioration of acne. Among them, acne causative bacteria secrete lipolytic enzymes, which break down triglycerides in sebum to form free fatty acids and stimulate hair follicles. In addition, the immunological response to acne causing bacteria contributes to the inflammatory response of acne. In other words, the causes of acne vary, but the main cause of acne is the cause of bacteria. Therefore, it is effective for skin diseases such as antioxidant effect, toxin discharge, acne and atopy which are excellent for treating the itching and skin purulence, and it is effective for treatment of itching pain, athlete's foot and eczema. A study on the development of acne treatment with natural extracts which exclude chemical components considering various side effects and inefficiency by using these three herb extracts, which are widely known to be effective for acne treatment in the market. Respectively. This study aims to break the preconceived notion that only chemical medicines have an antimicrobial effect and that it is possible to treat acne disease, and obtain a therapeutic agent which is suitable for skin and has no side effects.

본 발명은 상기와 같은 목적을 달성하기 위하여, 볼 용기의 피부에 닿는 볼 부분으로 용액이 나오게 되는 볼; 상기 용기의 볼과 용기의 몸통을 결합시키는 결합부; 추출물이 담아져 있고, 추출물 용액을 보호하기 위한 용기 몸통부; 용액형태의 추출물 치료제로 천연방부제 자몽씨 추출물 5중량%와 항균성을 띠는 추출물 고삼추출물30중량%, 마치현추출물30중량%, 어성초추출물30중량%, Staphylococcus hominis균 에 대한 치료제이다. 그 중 고삼은 여드름을 치료하는 데에 있어 효과가 입증되어 종종 여드름 치료제에 사용되는 어성초와 비슷한 수준의 항균 효과를 보여주었으며, 마치현은 그에 비해 미비한 항균 효과를 보여주었다. 고삼과 마치현 추출물을 같은 비율로 섞은 추출물은 이 중에서도 효과가 제일 뛰어났으며 이는 어성초를 조금이지만 능가하는 수준이었다. 따라서 정도에 차이가 있지만 어성초, 고삼, 마치현은 여드름 균 staphylococcus hominis에 대하여 항균 효과가 있음이 입증된 용액부; 용기의 세균오염을 막고 용액의 증발을 방지하기 위한 뚜껑부를 포함하도록 구성된다.In order to achieve the above-mentioned object, the present invention provides a ball, An engaging portion for engaging the bowl of the container with the body of the container; A container body for containing the extract and for protecting the extract solution; 5% by weight of a natural preservative grapefruit seed extract and 30% by weight of an extract gossam extract, antimicrobial extract, 30% by weight of extract, 30% by weight of an extract of Staphylococcus aureus , and Staphylococcus hominis . Among them, gosam has proven to be effective in treating acne, and has shown antibacterial effects similar to those of acacia, which is often used in acne treatments. Among the extracts, the extracts with the same ratio of Gossam and Matsumichi extracts showed the best effect, which was somewhat superior to the others. Thus, although there is a difference in the degree of difference, there is a proved solution for the antimicrobial effect against the acne bacteria staphylococcus hominis; And a lid for preventing bacterial contamination of the container and preventing evaporation of the solution.

이상과 같이 본 발명에 따르면, 세 차례의 실험 결과 피부 질환 치료에 도움이 되고 항균 효과가 뛰어나다고 알려진 약초 어성초, 고삼, 마치현이 여드름 균 staphylococcus hominis 뿐만 아니라 다양한 피부 질환균에 항균 효과가 있음이 입증 되었다. 이에 따라 여드름 치료제로써 시중에 널리 쓰이는 어성초 뿐만 아니라 고삼이나 마치현도 여드름 치료제로써 사용할 수 있는 가능성을 열었다고 볼 수 있다. 또한 다양한 피부 질환 원인균에 대하여 항균 효과가 있다는 장점을 이용하여 제작한 우리의 천연 치료제는 다른 치료제들과 같이 부작용을 야기하는 화학 성분은아예 배제하였을 뿐만 아니라 다른 천연 치료제들과는 달리 다양한 피부 질환 원인균을 치료 할 수 있는 피부 질환 원인균의 만병통치제와 같은 역할을 할 수 있다. 또한 천연 방부제 역할을 하는 자몽씨 추출물은 방부제 없이도 우리의 천연 치료제를 오래 보존 시킬 수 있다. 우리의 실험으로 인하여 고삼과 마치현이 다양한 피부 질환 원인균에 항균 효과가 있어 다양한 피부 질환을 치료할 수 있음을 알려 전보다 인체에는 무해하고 효과는 더 좋은 치료제를 만들 수 있을 것으로 예상된다. 이에 따라 치료제로 인한 부작용은 점차 줄어들 것이며, 인체에 해가 되지 않는 치료제를 개발하는 데에 기여 하였다고 할 수 있다.As described above, according to the present invention, it is proved that the herb acupuncture herb, Gosam, and Maichyung which are known to have excellent antimicrobial effect for the treatment of skin diseases after three tests have antibacterial effect against various skin diseases as well as acne staphylococcus hominis . As a result, it can be said that Gosam or Machi can be used as a therapeutic agent for acne as well as an acupuncture which is widely used in the market as an acne treatment agent. In addition, our natural remedy, which is made by taking advantage of its antibacterial effect against various skin diseases, has not only eliminated the chemical ingredients that cause side effects like other remedies, but also treated various skin diseases It can play the same role as a panacea that can cause skin diseases. In addition, grapefruit seed extract, which acts as a natural preservative, can preserve our natural remedy long without preservatives. Our experiments show that Gosam and Maji are antimicrobial against diverse skin diseases and can treat various skin diseases. It is expected that they will be able to make a better harmless and effective treatment for human body than before. As a result, the side effects caused by the therapeutic agent will be gradually reduced, contributing to the development of a therapeutic agent which is harmless to human body.

[도면1]은 사시도이고, [도면2]는 평면도 이다.FIG. 1 is a perspective view, and FIG. 2 is a plan view.

본 발명을 첨부된 도면을 참조하여 상세히 설명하면 다음과 같다.The present invention will now be described in detail with reference to the accompanying drawings.

첨부된 도면으로서, 도1은 발명에 따른 화학성분을 배제하여 천연성분을 이용한 여드름치료제 제작의 실시예를 도시한 사시도이고, 도2는 평면도이다.1 is a perspective view showing an embodiment of manufacturing an acne treatment agent using a natural component by excluding a chemical component according to the invention, and Fig. 2 is a plan view.

볼(10)은 볼 용기의 피부에 닿는 볼 부분으로 문지르면 용액이 나오게 되어 치료를 가능하게 한다.When the ball 10 is rubbed with the ball portion touching the skin of the ball container, the solution is released to enable the treatment.

볼과 용기몸통 결합부(20)은 상기 용기의 볼과 용기의 몸통을 결합시킨다.The ball and container body engaging portion 20 engages the bowl of the container with the body of the container.

용기몸통(30)은 추출물이 담아져 있고, 추출물 용액을 보호하기 위한 용기이다.The container body (30) contains the extract and is a container for protecting the extract solution.

용액(40)은 용액형태의 추출물 치료제로 천연방부제 자몽씨 추출물 5%와 항균성 추출물 고삼 30%, 마치현30%, 어성초30%, Staphylococcus hominis균 에 대한 항균성을 띤 치료제이다.Solution (40) is a therapeutic agent in the form of a solution in the form of a solution. It is a therapeutic agent with antimicrobial properties against 5% of natural preservative grapefruit seed extract and 30% of antimicrobial extracts, 30% of marcia, 30% of strains and Staphylococcus hominis .

뚜껑(50)은 용기의 세균오염을 막고 용액의 증발을 방지하기 위한 것이다.The lid 50 is for preventing bacterial contamination of the container and preventing evaporation of the solution.

이상, 첨부도면을 참조하여 본 발명의 바람직한 실시예에 대하여 상세히 설명하였으나, 이는 예시에 불과한 것이며 본 발명의 기술적 사상의 범주내에서 다양한 변형과 변경이 가능하다. 본 발명의 권리범위는 이하의 특허 청구범위의 기재에 의하여 정하여 져야 할 것이다.While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments, but, on the contrary, is intended to cover various modifications and equivalent arrangements included within the spirit and scope of the invention. The scope of the present invention should be defined by the following claims.

10 : 볼
20 : 볼과 용기몸통 결합부
30 : 용기몸통
40 : 용액
50 : 뚜껑
10: ball
20: ball and container body connecting part
30: container body
40: solution
50: Lid

Claims (1)

본 발명은 상기와 같은 목적을 달성하기 위하여, 볼 용기의 피부에 닿는 볼 부분으로 용액이 나오게 되는 볼; 상기 용기의 볼과 용기의 몸통을 결합시키는 결합부; 추출물이 담아져 있고, 추출물 용액을 보호하기 위한 용기 몸통부; 용액형태의 추출물 치료제로 천연방부제 자몽씨 추출물 5%와 항균성 추출물 고삼 30%, 마치현30%, 어성초30%, Staphylococcus hominis균 에 대한 항균성을 띤 치료제인 용액부; 용기의 세균오염을 막고 용액의 증발을 방지하기 위한 뚜껑으로 구성된 화학성분을 배제하여 천연성분을 이용한 여드름치료제 제작.In order to achieve the above-mentioned object, the present invention provides a ball, An engaging portion for engaging the bowl of the container with the body of the container; A container body for containing the extract and for protecting the extract solution; As a therapeutic agent of solution form, 5% of natural antiseptic grapefruit seed extract and 30% of antimicrobial extract, 30% of marine extract, 30% of maraschus, 30% of Staphylococcus hominis , Manufacture of acne remedy using natural ingredients by eliminating the chemical constituents consisting of lid to prevent bacterial contamination of container and prevent solution evaporation.
KR1020190006809A 2019-01-18 2019-01-18 Improvement Of Acne Treatment Using Natural Extract KR20190014008A (en)

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