KR20180090916A - Natural antibacterial composition using food by-product and method for manufacturing the same - Google Patents
Natural antibacterial composition using food by-product and method for manufacturing the same Download PDFInfo
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- KR20180090916A KR20180090916A KR1020170015541A KR20170015541A KR20180090916A KR 20180090916 A KR20180090916 A KR 20180090916A KR 1020170015541 A KR1020170015541 A KR 1020170015541A KR 20170015541 A KR20170015541 A KR 20170015541A KR 20180090916 A KR20180090916 A KR 20180090916A
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- A—HUMAN NECESSITIES
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Abstract
Description
본 발명은 식품 부산물을 이용한 천연 항균 조성물 및 이의 제조 방법에 관한 것으로, 보다 상세하게는 식품 부산물인 커피박, 감귤피 및 황금박을 이용하여 제조한 천연 항균 조성물에 관한 것이다.The present invention relates to a natural antimicrobial composition using food byproducts and a method of preparing the same, and more particularly to a natural antimicrobial composition prepared by using coffee beans, citrus peel, and golden foil as food byproducts.
환경부에서 발표한 2015년도 전국 폐기물 발생 및 처리 현황 자료에 따르면, 분리배출되는 음식물 쓰레기의 양은 하루 약 1만 3천 톤으로, 연간 약 500만 톤에 달하고 있다. 이러한 음식물 쓰레기를 처리하기 위해 매우 높은 수준의 사회적 비용이 소요되고 있다.According to the Ministry of Environment's 2015 national waste disposal and disposal data, the amount of separated food waste is about 13,000 tons per day, reaching about 5 million tons per year. There is a very high level of social cost to process such food waste.
음식물 쓰레기 중 약 10%는 잔여 음식물이 아닌 식품 부산물이 차지하고 있다. 이에 따라 식품 부산물을 다양한 산업 분야에 이용함으로써 음식물 쓰레기 처리에 소요되는 비용을 저감하면서도, 산업적 부가 가치를 창출할 수 있는 기술에 대한 관심이 증대되고 있다.About 10% of food waste is made up of food byproducts, not residual food. Accordingly, by using food byproducts in various industrial fields, there is a growing interest in technologies that can create industrial added value while reducing the cost of food waste processing.
한편, 일상 생활 속 미생물 번식에 의한 비위생적인 환경을 개선하고자 다양한 종류의 항균 관련 제품들이 이용되고 있다. 소독제, 세정제 등과 같은 항균 제품은 일부 석유화학계 원료 또는 합성 계면활성제 등의 화학적 합성 항균 물질을 포함하고 있어 강력한 항균성을 구현할 수 있다. On the other hand, various kinds of antimicrobial-related products are being used to improve the unsanitary environment caused by microbial propagation in daily life. Antimicrobial products such as disinfectants, detergents and the like contain chemically synthesized antimicrobial substances such as petrochemical raw materials or synthetic surfactants, thus realizing strong antimicrobial properties.
그러나, 화학적 합성 항균 물질을 포함하는 제품의 경우 주요 성분들이 쉽게 휘발되어 항균 지속성이 유지하기 어려우며, 화학적 합성 항균 물질에 대한 인체의 반응이 충분히 규명되지 않은 부분이 있다. 이에 따라, 최근에는 천연 유래의 물질을 이용하면서도 우수한 항균성을 갖는 물질에 대한 수요가 급증하고 있으나, 천연 물질만을 이용하여 충분히 우수한 수준의 항균 활성을 구현하는 것은 쉽지 않다.However, in the case of a product containing a chemically synthesized antimicrobial substance, the main components are easily volatilized, so that it is difficult to maintain the antimicrobial persistence, and the reaction of the human body to the chemically synthesized antimicrobial substance is not fully understood. Accordingly, in recent years, there has been a rapid increase in demand for a substance having excellent antibacterial activity while using a substance derived from a natural origin, but it is difficult to realize a sufficiently high level of antibacterial activity using only natural substances.
따라서, 잔류 활성이 강하여 항균 지속성이 높으면서도, 항균성이 우수하고, 인체에 무해한 천연 항균 조성물 및 이의 제조 방법에 대한 관심이 증대되고 있다. Therefore, there is a growing interest in a natural antimicrobial composition having high antimicrobial persistence and excellent antimicrobial activity and being harmless to the human body and a method for producing the same, because of its strong residual activity.
본 발명의 하나의 목적은 식품 부산물을 활용하여 경제성이 우수하면서도 황색포도상구균, 대장균 및 일반세균에 대한 항균 활성이 우수하고, 잔류활성이 강하여 항균 지속성이 높고, 환경 친화적인 천연 항균 조성물 및 이의 제조 방법을 제공하는 것이다.It is an object of the present invention to provide a natural antimicrobial composition having excellent antimicrobial activity against Staphylococcus aureus, Escherichia coli, and common bacteria, which is excellent in economic efficiency by utilizing food byproducts, has high persistence of antibacterial activity and is highly environmentally friendly, Method.
본 발명의 일 구현예는 커피박 추출물, 감귤피 추출물, 황금박 추출물 및 주정을 포함하는 천연 항균 조성물에 관한 것이다.One embodiment of the present invention relates to a natural antimicrobial composition comprising a coffee ground extract, a citrus peel extract, a golden foaming extract and a spatula.
본 발명의 다른 구현예는 커피박 및 황금박 혼합물에 정제수를 가하여 제1혼합액을 제조하는 단계; 감귤피 추출물 및 주정을 혼합하여 제2혼합액을 제조하는 단계; 및 상기 제1혼합액 및 제2혼합액을 혼합하는 단계; 를 포함하는 천연 항균 조성물 제조 방법에 관한 것이다.Another embodiment of the present invention is a method for producing a coffee beverage comprising the steps of: adding purified water to a coffee bean and a golden foil mixture to prepare a first mixture; Preparing a second mixture liquid by mixing citrus peel extract and alcohol; And mixing the first mixed liquid and the second mixed liquid; To a method for producing a natural antimicrobial composition.
상기 천연 항균 조성물은 커피박 추출물 5 중량% 내지 15 중량%, 감귤피 추출물 65 중량% 내지 85 중량%, 황금박 추출물 1 중량% 내지 10 중량% 및 주정 5 중량% 내지 10 중량%를 포함할 수 있다.The natural antimicrobial composition may comprise from 5% to 15% by weight of coffee bean extract, from 65% to 85% by weight of citrus peel extract, from 1% to 10% by weight of golden foil extract and from 5% to 10% have.
상기 천연 항균 조성물 중 황금박 추출물 및 커피박 추출물의 중량비는 1:5 내지 1:15일 수 있다.The weight ratio of the golden foil extract and the coffee foil extract in the natural antimicrobial composition may be 1: 5 to 1:15.
상기 혼합물 중 황금박 및 커피박의 중량비는 1:5 내지 1:15일 수 있다.The weight ratio of the golden foil and the coffee foil in the mixture may be from 1: 5 to 1:15.
상기 천연 항균 조성물은 제1혼합액 10 중량% 내지 30 중량% 및 제2혼합액 70 중량% 내지 90 중량%를 포함할 수 있다.The natural antimicrobial composition may include 10 wt% to 30 wt% of the first mixed solution and 70 wt% to 90 wt% of the second mixed solution.
상기 주정은 사카로미세스 세레비시아(Saccharomyces cerevisiae)의 알코올발효에 의해 제조된 알코올 성분을 95% 내지 99%로 포함하는 것일 수 있다.The alcohol may contain 95% to 99% of an alcohol component produced by alcohol fermentation of Saccharomyces cerevisiae.
상기 천연 항균 조성물은 황색포도상구균 및 대장균에 대한 항균력을 갖고, 피부외용, 식품용 및 식기세정용 중 1종 이상으로 적용될 수 있다. The natural antimicrobial composition has antimicrobial activity against Staphylococcus aureus and Escherichia coli, and can be applied to at least one of skin, food, and tableware.
본 발명은 식품 부산물을 이용하여 황색포도상구균, 대장균 및 일반세균에 대한 항균 활성이 우수하고, 잔류활성이 강하여 항균 지속성이 높고, 환경 친화적이며, 피부외용 및 식품용으로 사용가능한 천연 항균 조성물 및 이의 제조 방법을 제공하는 효과가 있다.The present invention relates to a natural antimicrobial composition which is excellent in antimicrobial activity against Staphylococcus aureus, Escherichia coli and common bacteria by using food byproducts and has high persistence of antimicrobial activity due to strong residual activity, environmentally friendly, There is an effect of providing a manufacturing method.
도 1은 본 발명 일 실시예의 천연 항균 조성물 제조 방법을 나타낸 순서도이다.
도 2는 본 발명 실시예 1의 천연 항균 조성물 제조 과정을 사진으로 나타낸 것이다.
도 3은 본 발명 실시예 1의 천연 항균 조성물에 대한 항균성 평가 결과를 나타낸 것이다.
도 4는 본 발명 실시예 1의 천연 항균 조성물을 적용한 스프레이 세정제 제품을 나타낸 것이다.BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a flowchart showing a method for producing a natural antimicrobial composition according to an embodiment of the present invention.
FIG. 2 is a photograph showing the process of manufacturing the natural antimicrobial composition of Example 1 of the present invention.
3 shows the results of evaluation of antimicrobial activity against the natural antimicrobial composition of Example 1 of the present invention.
4 shows a spray cleaner product to which the natural antimicrobial composition of Example 1 of the present invention is applied.
본 발명은 식품 부산물인 커피박 추출물, 감귤피 추출물, 황금박 추출물 및 주정을 포함하는 천연 항균 조성물 및 이의 제조 방법에 관한 것이다. 이를 통해, 본 발명은 식품 부산물을 이용하여 황색포도상구균, 대장균 및 일반세균에 대한 항균 활성이 우수하고, 잔류활성이 강하여 항균 지속성이 높고, 환경 친화적인 천연 항균 조성물 및 이의 제조 방법을 제공한다.The present invention relates to a natural antimicrobial composition comprising a coffee bean extract, a citrus peel extract, a golden foil extract and a spice, which are food byproducts, and a method for producing the same. Accordingly, the present invention provides a natural antimicrobial composition having high antimicrobial activity against Staphylococcus aureus, Escherichia coli, and common bacteria using food byproducts, high persistence of antimicrobial activity and high environmental stability, and a method for producing the same.
특히, 본 발명의 천연 항균 조성물은 천연 유래의 식품 부산물을 활용함으로써, 피부외용, 식품용, 식기세정용, 유아용 제품 등으로 적용하기에 적합한 환경 친화성, 인체 안정성, 무자극성 및 항균성을 구현할 수 있으며, 교차 오염에 의한 미생물 번식도 현저하게 감소시킬 수 있다.In particular, the natural antimicrobial composition of the present invention can be applied to natural, food-grade, food-cleaning, and infant products by utilizing natural-derived food byproducts, thereby achieving environmental compatibility, human stability, non-irritating and antimicrobial properties And the microbial propagation due to cross contamination can be remarkably reduced.
보다 구체적으로, 본 발명은 손 소독제, 손 세정제 등의 피부 외용제, 항균제, 소독제, 방부제, 보존제 등의 식품용 첨가제, 식기 소독제, 식기 세정제 등의 식기 세정제, 유아용 세정제, 유아용 완구 등의 유아용 제품으로 적용될 수 있으나, 이에 제한되지 않는다.More specifically, the present invention relates to a food product such as a disinfectant for a hand, an external agent for a skin such as a hand cleanser, an antimicrobial agent, a disinfectant, a food additive such as a preservative or a preservative, a dish disinfectant, a dishwashing detergent such as a dishwashing detergent, But is not limited thereto.
본 발명의 천연 항균 조성물은 커피박 추출물을 포함한다. 커피박은 천연 물질만으로 우수한 향기를 구현할 수 있어 제품에 대한 소비자의 기호성을 향상시킬 수 있을 뿐만 아니라, 커피박에 포함된 잔여의 카페인, 폴리페놀 화합물 등에 의한 소취 효과 및 항균 효과를 구현할 수 있다. The natural antimicrobial composition of the present invention comprises coffee bean extract. The coffee bean can realize excellent fragrance by using only the natural substance, thereby improving the palatability of the consumer to the product, and can realize the deodorizing effect and the antibacterial effect by residual caffeine and polyphenol compound contained in the coffee bean.
상기 커피박 추출물은 후술하는 황금박 추출물과 복합적으로 작용하여 황색 포도상구균 및 대장균에 대해 특히 우수한 항균력을 구현할 수 있다.The coffee ground extract may be combined with a golden foil extract to be described below to provide particularly excellent antibacterial activity against Staphylococcus aureus and Escherichia coli.
상기 천연 항균 조성물 중 커피박 추출물은 5 중량% 내지 15 중량%으로 포함될 수 있다. 상기 범위 내에서, 커피박에서 유래한 커피향이 불쾌한 느낌의 화독향(탄냄새)으로 변질되는 것을 저감하면서, 더욱 우수한 소취 효과 및 항균 효과를 구현할 수 있다.The coffee bean extract in the natural antimicrobial composition may be included in an amount of 5 to 15% by weight. Within the above range, it is possible to realize a more excellent deodorizing effect and an antibacterial effect while reducing the deterioration of the coffee aroma derived from coffee grounds to the unpleasant burning incense (burning odor).
본 발명의 천연 항균 조성물은 황금박 추출물을 포함한다. 황금(Scutellaria baicalensis)은 체내에 열이 과다하게 쌓여서 일어나는 안구충혈과 동통을 제거하고, 찬 약성으로 열을 내리는 효과가 있고, 항염증반응, 항병원 미생물작용, 해열·이뇨·혈압강하작용, 혈당 및 고지혈증 강하, 담즙 분비 촉진, 진정 작용 등의 효과가 있는 생약 성분으로 알려져있다. 본 발명의 천연 항균 조성물은 황금박, 예를 들면 황금 뿌리의 박을 이용하여, 황금의 생약적 특성을 보존하고 항균 효과를 구현할 뿐 아니라, 피부 외용 제품으로의 적용 시 항염증 반응, 피부발적 완화, 피부 진정 작용 등을 부여할 수 있다. 또한, 황금박은 커피박의 커피향이 불쾌한 느낌의 화독향(탄냄새)으로 변질되는 것을 저감하는 효과를 구현할 수 있다. The natural antimicrobial composition of the present invention comprises a golden foil extract. Gold (Scutellaria baicalensis) has the effect of eliminating redness and pain caused by excessive accumulation of heat in the body, and it has the effect of lowering fever with cold. It has anti-inflammatory reaction, anti-hospital microbial action, fever, diuretic, hypotensive effect, And is known as a herbal medicine ingredient having effects such as hypolipidemia, promotion of bile secretion, sedation and the like. The natural antimicrobial composition of the present invention preserves the herbicidal properties of gold by using a golden foil, for example, a foil of a golden root, and not only realizes an antibacterial effect, but also provides an anti-inflammatory reaction, , Skin soothing action, and the like. In addition, the golden foil can realize the effect of reducing the deterioration of the coffee aroma of the coffee beans into the unpleasant burning incense (burning odor).
상기 황금박 추출물은 전술한 커피박 추출물과 복합적으로 작용하여 황색 포도상구균 및 대장균에 대해 특히 우수한 항균력을 구현할 수 있다.The golden foil extract works in combination with the above-mentioned coffee foil extract to achieve particularly excellent antibacterial activity against Staphylococcus aureus and E. coli.
상기 천연 항균 조성물 중 황금박 추출물은 1 중량% 내지 10 중량%로 포함될 수 있다. 상기 범위 내에서, 커피박에서 유래한 커피향이 변질되는 것을 저감하면서, 더욱 우수한 항균 효과 및 피부 진정 작용을 구현할 수 있다.The natural antimicrobial composition may contain 1 to 10% by weight of the extract. Within this range, it is possible to realize more excellent antibacterial effect and skin soothing action while reducing the deterioration of the coffee aroma derived from coffee grounds.
상기 천연 항균 조성물 중 황금박 추출물 및 커피박 추출물의 중량비는 1:5 내지 1:15일 수 있다. 상기 범위 내에서, 황금박 추출물 및 커피박 추출물에 의한 항균 작용이 농도에 비례하여 증가하면서, 커피박의 커피향이 불쾌한 느낌의 화독향(탄냄새)으로 변질되는 것을 저감하는 효과를 더욱 향상시킬 수 있다.The weight ratio of the golden foil extract and the coffee foil extract in the natural antimicrobial composition may be 1: 5 to 1:15. Within the above range, the antibacterial action by the golden foil extract and the coffee foil extract is increased in proportion to the concentration, and the effect of reducing the deterioration of the coffee fragrance of the coffee foil to the unpleasant burning incense (burning odor) can be further improved have.
상기 황금박 추출물 및 커피박 추출물의 중량비는 구체적으로 1:7 내지 1:13, 보다 구체적으로 1:9 내지 1:11, 일 구체예에서 1:10 일 수 있다. 이러한 경우, 전체 천연 항균 조성물의 항균성이 더욱 우수하면서, 각 성분들 간의 상용성, 혼용성 등이 향상되어 제형 안정성이 우수할 수 있다.The weight ratio of the golden foil extract to the coffee foil extract may be specifically from 1: 7 to 1:13, more specifically from 1: 9 to 1:11, and in one embodiment, from 1:10. In this case, the antimicrobial activity of the whole natural antimicrobial composition is more excellent, and the compatibility and miscibility of the respective components are improved, so that the formulation stability can be excellent.
본 발명의 천연 항균 조성물은 감귤피 추출물을 포함한다. 감귤피는 리모넨(d-limonene) 화합물 등을 포함하고 있어, 상쾌한 향기와 함께 항균 효과를 구현할 수 있어 제품에 대한 소비자의 기호성을 향상시킬 수 있다. 뿐만 아니라, 감귤피에 포함된 잔여의 폴리페놀 화합물, 정유 성분, 에스테르 성분, 카로티노이드, 폴라보노이드 및 각종 비타민 등에 의한 생리기능활성 효과를 천연 항균 조성물에 부여할 수 있다. 또한, 감귤피 추출물은 정유 성분 등에 의해 잔류 활성이 강하여 천연 항균 조성물의 항균 지속성을 더욱 높일 수 있다. The natural antimicrobial composition of the present invention includes citrus peel extract. D-limonene compound, and the like, and it is possible to realize an antimicrobial effect together with a refreshing aroma, thereby improving the palatability of a consumer to a product. In addition, the natural antimicrobial composition can be imparted with a physiological function activity effect by remaining polyphenol compounds, essential oil components, ester components, carotenoids, polycarbonate, various vitamins and the like contained in citrus peel. Also, the citrus extract has a strong residual activity due to an essential oil component and the like, so that the antimicrobial persistence of the natural antimicrobial composition can be further enhanced.
상기 천연 항균 조성물 중 감귤피 추출물은 65 중량% 내지 85 중량%로 포함될 수 있다. 상기 범위 내에서, 감귤피 추출물은 커피박에서 유래된 커피향과 주정과 혼합되어 형성되는 휘발성 향을 감소시키고 상쾌한 향기를 구현하는 효과가 더욱 우수하며, 동시에 항균 활성이 더욱 향상될 수 있다.In the natural antimicrobial composition, citrus peel extract may be contained in an amount of 65 wt% to 85 wt%. Within the above-mentioned range, the citrus peel extract has a better effect of reducing coffee aroma derived from coffee grounds and volatile flavor mixed with alcohol, realizing a refreshing aroma, and at the same time, improving antimicrobial activity.
본 발명의 천연 항균 조성물은 주정을 포함한다. 이를 통해 천연 항균 조성물은 천연 물질만으로 우수한 소취 효과 및 항균 효과를 구현할 수 있다. The natural antimicrobial compositions of the present invention include spirits. As a result, the natural antimicrobial composition can achieve an excellent deodorizing effect and an antimicrobial effect using only natural substances.
상기 천연 항균 조성물 중 주정은 5 중량% 내지 10 중량%로 포함될 수 있다. 상기 범위 내에서, 항균, 소독, 세정 효과를 더욱 향상시키면서도, 천연 항균 조성물의 휘발성을 과도하게 높이지 않아 잔류 활성을 높이고 천연 항균 조성물의 항균 지속성을 더욱 높일 수 있다. The natural antimicrobial composition may contain 5 wt% to 10 wt% of the alcohol. Within the above range, the volatile property of the natural antimicrobial composition is not excessively increased while the antibacterial, disinfection, and cleaning effect are further improved, so that the residual activity can be enhanced and the antimicrobial persistence of the natural antimicrobial composition can be further enhanced.
상기 주정은 특별히 제한되지 않으나, 예를 들면 사카로미세스 세레비시아(Saccharomyces cerevisiae)의 알코올 발효에 의해 제조된 알코올 성분을 95% 내지 99%로 포함하는 것일 수 있다. 이러한 경우, 환경 친화적 효과를 더욱 증대하고, 인체 안정성, 무자극성 및 항균성을 더욱 향상시킬 수 있다. The alcohol is not particularly limited, and may be, for example, 95% to 99% of an alcohol component produced by alcohol fermentation of Saccharomyces cerevisiae. In this case, the environment-friendly effect can be further increased, and human stability, non-irritating and antimicrobial properties can be further improved.
구체적으로, 상기 알코올 발효는 당분(포도당, 설탕, 탄수화물 등)계 원료를 사카로미세스 세레비시아 효모균을 이용하여 알코올 발효 후, 균체를 제거하고 알코올 성분이 알코올 성분을 95% 내지 99%가 되도록 증류 농축한 것일 수 있으나, 이에 제한되지 않는다.Specifically, the alcohol fermentation is carried out by using saccharomyces cerevisiae yeast as a raw material of sugar (glucose, sugar, carbohydrate, etc.), removing the cells after alcohol fermentation so that the alcohol component is 95% to 99% But it is not limited thereto.
본 발명의 천연 항균 조성물은 황색포도상구균, 대장균 및 일반세균에 대한 항균력을 가질 수 있다.The natural antimicrobial composition of the present invention may have antibacterial activity against Staphylococcus aureus, Escherichia coli and common bacteria.
황색포도상구균(Staphylococcus aureus)은 생육함에 따라 세포집괴(덩어리)를 형성하는 그람양성의 통성혐기성 세균으로, 건강한 사람이나 가축의 피부와 비강표면에 일반적으로 존재한다. 내열성인 외독소를 생산하여 식중독을 일으키거나, 식세포를 죽이는 독소(류코시딘), 용혈소, 응고효소 등을 분비하여 감염숙주세포의 저항성에서 벗어나 화농성 감염증을 일으킬 수 있다. Staphylococcus aureus is a gram-positive, tuberous anaerobic bacterium that forms cell clumps (lumps) as it grows, and is commonly found on skin and nasal surfaces of healthy people or livestock. It can produce toxic toxins (leucocidin), hemolyzes, coagulation enzymes which cause food poisoning by producing heat-resistant exotoxin, and can cause a pneumococcal infection by deviating from the resistance of infected host cells.
대장균(Escherichia coli)은 사람을 포함하는 포유류의 장관을 기생 장소로 이용하는 장내세균으로, 통성혐기성 그람음성의 간균이며 글루코오스를 분해하여 산을 생산한다. Escherichia coli is a intestinal bacteria that uses the intestines of mammals, including humans, as a parasitic site. It is a tuberous anaerobic gram-negative bacterium and produces acid by decomposing glucose.
본 발명의 천연 항균 조성물은 상기 황색포도상구균 및 상기 대장균, 이외의 일반세균에 대해 특히 우수한 항균력을 구현할 수 있어 일상 생활 속 세균의 증식을 억제하는 효과가 우수하다. 이러한 특성의 의해, 본 발명의 천연 항균 조성물은 피부외용, 식품용, 식기세정용, 유아용 제품 등으로 적용하기에 더욱 적합한 환경 친화성, 인체 안정성, 무자극성 및 항균성을 구현할 수 있으며, 교차 오염에 의한 미생물 번식도 현저하게 감소시킬 수 있다.The natural antimicrobial composition of the present invention is particularly excellent in antimicrobial activity against the above-mentioned Staphylococcus aureus and the above-mentioned E. coli, and thus has an excellent effect of inhibiting the proliferation of bacteria in everyday life. By virtue of these properties, the natural antimicrobial composition of the present invention can realize environmental friendliness, human stability, non-irritating and antimicrobial properties more suitable for application to skin, foods, dishes and baby products, It is possible to remarkably reduce the microbial propagation caused by the microorganisms.
첨부된 도 1는 본 발명 일 실시예의 천연 항균 조성물 제조 방법을 나타낸 순서도이며, 도 2는 이에 따른 실시예 1의 천연 항균 조성물 제조 공정을 나타낸 사진이다. 도 1 및 2를 참조하면 본 발명의 다른 구현예는 커피박 및 황금박 혼합물에 정제수를 가하여 제1혼합액을 제조하는 단계(A); 감귤피 추출물 및 주정을 혼합하여 제2혼합액을 제조하는 단계(B); 및 상기 제1혼합액 및 제2혼합액을 혼합하여 천연 항균 조성물 제조 방법(C)에 관한 것이다. 또한, 커피박, 황금박, 감귤피 등의 원료를 준비하고 정량하는 원료 준비 단계(P)를 더 포함할 수도 있다.FIG. 1 is a flow chart showing a method of manufacturing a natural antimicrobial composition according to an embodiment of the present invention, and FIG. 2 is a photograph showing a manufacturing process of a natural antimicrobial composition according to Example 1. Referring to FIGS. 1 and 2, another embodiment of the present invention provides a process for producing a coffee beverage, comprising: (A) preparing purified water by adding purified water to a coffee bean and a golden foil mixture; (B) mixing the citrus peel extract and the alcohol to prepare a second mixed solution; And a method (C) for producing a natural antimicrobial composition by mixing the first mixed liquid and the second mixed liquid. In addition, it may further comprise a raw material preparation step (P) for preparing and quantifying raw materials such as coffee beans, golden foil, citrus peel, and the like.
본 발명의 천연 항균 조성물 제조 방법은 커피, 황금 및 감귤 각각의 부산물을 이용하여 천연 항균 조성물을 제조한다. 본 명세서에서 각각 커피박, 황금박 및 감귤피(감귤박)은 해당 원료를 산업적 또는 그외의 목적으로 활용하고 남은 부산물을 의미한다. 또한, 본 발명의 천연 항균 조성물 제조 방법에서 커피박, 황금박, 감귤피 및 주정등의 원료에 대한 내용은 앞서 서술한 내용과 동일하다.The method for producing a natural antimicrobial composition of the present invention produces a natural antimicrobial composition using by-products of coffee, gold and citrus, respectively. In the present specification, coffee beans, golden foil and citrus peel (citrus peel) mean byproducts which utilize the raw materials for industrial or other purposes. Further, in the method for producing a natural antimicrobial composition of the present invention, the contents of raw materials such as coffee beans, golden foil, citrus peel, and alcohol are the same as described above.
예를 들면, 커피박은 커피 원두 가루를 분쇄하여 커피 원액을 추출하고 남은 커피 부산물일 수 있고, 황금박은 황금 뿌리 건조물로부터 생약 성분을 추출하고 남은 부산물일 수 있고, 감귤피는 감귤의 껍질 또는 이의 건조물 등일 수 있다. For example, the coffee bean may be a coffee by-product obtained by grinding the coffee bean powder to extract the coffee bean powder, and the golden bean may be a by-product after extracting the herbal ingredient from the dried golden bean root, or the bark of citrus peel, .
본 발명은 이러한 부산물 등을 활용하여 식품 부산물을 재활용하면서도, 자원의 낭비를 막고 우수한 항균 효과를 구현하는 천연 항균 조성물을 제조할 수 있다. 이를 통해 본 발명의 천연 항균 조성물 제조 방법 식품 부산물 재활용, 및 부가가치 창출에 의한 원료 단가를 낮추면서도, 항균 활성은 높고 잔류 활성이 우수하여 지속력이 높은 천연 항균 조성물 제품을 제공할 수 있다. The present invention can produce a natural antimicrobial composition that uses waste materials such as by-products to recycle food byproducts while preventing waste of resources and realizing an excellent antimicrobial effect. Accordingly, it is possible to provide a natural antimicrobial composition product having high antimicrobial activity and high residual activity and low in raw material cost due to recycling of food byproducts and added value, and having high persistence, through the process for producing the natural antimicrobial composition of the present invention.
본 발명의 천연 항균 조성물 제조 방법 중 커피박 및 황금박 혼합물에 정제수를 가하여 제1혼합액을 제조하는 단계는 커피박 및 황금박의 혼합물로부터 항균성 및 방향성을 갖는 수용성 추출물을 수득할 수 있다. In the process for preparing the natural antibacterial composition of the present invention, the step of adding the purified water to the coffee beans and the golden foil mixture to prepare the first mixed solution can obtain a water-soluble extract having antimicrobial activity and aromaticity from the mixture of coffee beans and golden foil.
커피박과 황금박을 혼합한 후, 상기 혼합물로부터 추출물을 얻음으로써 커피박과 황금박의 상용성을 자연히 증대시킬 수 있으며, 커피박에서 유래한 커피향이 변질되는 것을 저감하면서, 더욱 우수한 항균 효과를 구현할 수 있다.By mixing a coffee bean and a golden foil and obtaining an extract from the mixture, it is possible to naturally increase the compatibility of the coffee bean and the golden foil, and it is possible to reduce the deterioration of the coffee fragrance derived from the coffee bean, Can be implemented.
상기 정제수는 특별히 제한되지 않으며, 식용 가능한 것을 사용하는 경우 이에 의한 부가적인 취식성 향상의 효과를 구현할 수 있다.The purified water is not particularly limited, and when it is possible to use an edible material, it is possible to realize the effect of improving the picking performance.
상기 황금박 및 커피박의 중량비는 1:5 내지 1:15일 수 있다. 상기 범위 내에서, 황금박 및 커피박에 의한 항균 작용이 농도에 비례하여 증가하면서, 커피박의 커피향이 불쾌한 느낌의 화독향(탄냄새)으로 변질되는 것을 저감하는 효과를 더욱 향상시킬 수 있다.The weight ratio of the golden foil and the coffee foil may be from 1: 5 to 1:15. Within this range, the antimicrobial action by the golden foil and the coffee foil increases in proportion to the concentration, and the effect of reducing the deterioration of the coffee fragrance of the coffee foil to the unpleasant burning incense (burning odor) can be further improved.
상기 황금박 및 커피박의 중량비는 구체적으로 1:7 내지 1:13, 보다 구체적으로 1:9 내지 1:11, 일 구체예에서 1:10 일 수 있다. 이러한 경우, 전체 천연 항균 조성물의 항균성이 더욱 우수하면서, 각 성분들 간의 상용성, 혼용성 등이 향상되어 제형 안정성이 우수할 수 있다.The weight ratio of the golden foil and the coffee foil may be specifically from 1: 7 to 1:13, more specifically from 1: 9 to 1:11, and in one embodiment, from 1:10. In this case, the antimicrobial activity of the whole natural antimicrobial composition is more excellent, and the compatibility and miscibility of the respective components are improved, so that the formulation stability can be excellent.
본 발명의 천연 항균 조성물 제조 방법 중 감귤피 추출물 및 주정을 혼합하여 제2혼합액을 제조하는 단계는 감귤피 추출물과 주정을 미리 혼합하여 상용성을 높이면서, 정유 성분 등의 분산성을 향상시켜 천연 항균 조성물의 잔류 활성을 더욱 향상시킬 수 있다.The step of preparing the second mixed solution by mixing the citrus peel extract and the alcohol in the natural antimicrobial composition manufacturing method of the present invention can improve the dispersibility of the essential oil component and the like by enhancing the compatibility by premixing the citrus extract and the alcohol, The residual activity of the antimicrobial composition can be further improved.
구체적으로, 상기 감귤피 추출물은 감귤피를 동결 건조한 후 미세분말화하여 주정에 용해시킬 수 있다. 이러한 경우, 감귤피 또는 감귤피 추출물에 포함된 정유 성분의 가용성을 향상시키고, 전술한 제1혼합액과의 상용성을 더욱 향상시킬 수 있다. Specifically, the citrus peel extract can be lyophilized and then finely powdered to dissolve in the alcohol. In this case, the solubility of the essential oil component contained in the citrus peel or citrus peel extract can be improved, and the compatibility with the above-mentioned first mixed solution can be further improved.
일 구체예에서, 감귤피 추출물은 감귤피를 동결 건조한 후 미세분말화하여 용매에 용해시킨 후, 여과하는 과정을 추가로 수행하여 감귤피 추출물을 수득한 후, 이를 동결건조하여 주정과 함께 사용할 수도 있다. 이러한 경우, 감귤피 고형물에 의한 잔여물이 발생하는 것을 방지하여, 천연 항균 조성물의 제형성을 더욱 향상시킬 수 있다.In one embodiment, the citrus peel extract is prepared by lyophilizing citrus peel, finely powdering it, dissolving it in a solvent, and then filtering the citrus peel extract to obtain citrus peel extract, which can be lyophilized have. In such a case, it is possible to prevent the residue from being caused by the tangerine-solids, thereby further improving the formation of the natural antimicrobial composition.
상기 동결건조 방법은 특별히 제한되지 않으며, 예를 들면, -30℃ 내지 0℃ 의 온도에서 급속 냉동하는 방법일 수 있다.The lyophilization method is not particularly limited and may be, for example, rapid freezing at a temperature of -30 ° C to 0 ° C.
본 발명의 천연 항균 조성물 제조 방법 중 상기 제1혼합액 및 제2혼합액을 혼합하는 것을 포함한다. 이러한 경우, 친수성이 우수한 제1혼합액과 친수성 및 친유성을 모두 갖는 제2혼합액의 상용성이 더욱 향상될 수 있으며, 향기의 조합이 자연스럽게 균형을 이룰 수 있어 기호성이 더욱 향상될 수 있다.And mixing the first mixture solution and the second mixture solution in the method for producing a natural antimicrobial composition of the present invention. In this case, the compatibility of the first mixed liquid having excellent hydrophilicity and the second mixed liquid having both hydrophilic and lipophilic properties can be further improved, and the combination of fragrance can naturally be balanced, and the palatability can be further improved.
상기 제1혼합액 및 제2혼합액을 혼합하는 방법은 특별히 제한되지 않으며, 예를 들면, 와류 혼합기(vortex), 초음파 분산기(sonificator), 마이크로 믹서(micro mixer) 등의 기기를 이용해 분산성이 우수하도록 혼합하는 방법일 수 있으나, 이에 제한되지 않는다.The method of mixing the first mixture solution and the second mixture solution is not particularly limited. For example, a method using a vortex mixer, a sonicator, a micromixer, But the present invention is not limited thereto.
상기 천연 항균 조성물은 제1혼합액 10 중량% 내지 30 중량% 및 제2혼합액 70 중량% 내지 90 중량%를 포함할 수 있다. 상기 범위 내에서, 커피박에서 유래된 커피향이 주정과 혼합되어 형성되는 휘발성 향을 감소시키고 상쾌한 향기를 구현하는 효과가 더욱 우수하며, 동시에 항균 활성이 더욱 향상될 수 있다.The natural antimicrobial composition may include 10 wt% to 30 wt% of the first mixed solution and 70 wt% to 90 wt% of the second mixed solution. Within this range, the coffee aroma derived from the coffee bean is mixed with the alcohol to reduce the volatile flavor formed, and the effect of realizing a refreshing aroma is further improved, and the antibacterial activity can be further improved.
보다 구체적으로, 상기 천연 항균 조성물은 제1혼합액은 커피박 추출물 5 중량% 내지 15 중량% 및 황금박 추출물 5 중량% 내지 15 중량%을 포함하고, 상기 제2혼합액은 감귤피 추출물 65 중량% 내지 85 중량% 및 주정 5 중량% 내지 10 중량%를 포함할 수 있다. 상기 범위 내에서, 커피박, 황금박 및 감귤피에 유래된 방향성분의 조합이 우수하여 상쾌한 향기를 구현하는 효과가 더욱 우수하며, 천연 항균 조성물의 잔류 활성이 우수하여 항균성이 오래 높은 수준으로 유지되고, 동시에 항균 활성이 더욱 향상될 수 있다.More specifically, the natural antimicrobial composition comprises 5 to 15% by weight of coffee bean extract and 5 to 15% by weight of golden foil extract, wherein the first mixture contains 65% 85 wt% and 5 wt% to 10 wt% of the alcohol. Within the above range, the combination of aroma components derived from coffee beans, golden foil and citrus peel is excellent, and the effect of realizing a refreshing aroma is excellent, and the residual activity of the natural antimicrobial composition is excellent, And at the same time, the antibacterial activity can be further improved.
본 발명의 제조 방법에 의해 제조된 천연 항균 조성물은 상기 황색포도상구균 및 상기 대장균, 이외의 일반세균에 대해 특히 우수한 항균력을 구현할 수 있어 일상 생활 속 세균의 증식을 억제하는 효과가 우수하다. 이러한 특성의 의해, 본 발명의 천연 항균 조성물은 피부외용, 식품용, 식기세정용, 유아용 제품 등으로 적용하기에 더욱 적합한 환경 친화성, 인체 안정성, 무자극성 및 항균성을 구현할 수 있으며, 교차 오염에 의한 미생물 번식도 현저하게 감소시킬 수 있다.The natural antimicrobial composition produced by the production method of the present invention can exert particularly excellent antimicrobial activity against the above-mentioned Staphylococcus aureus and the common bacteria other than the above-mentioned E. coli, so that the effect of suppressing the growth of bacteria in everyday life is excellent. By virtue of these properties, the natural antimicrobial composition of the present invention can realize environmental friendliness, human stability, non-irritating and antimicrobial properties more suitable for application to skin, foods, dishes and baby products, It is possible to remarkably reduce the microbial propagation caused by the microorganisms.
실시예Example
이하, 본 발명의 바람직한 실시예를 통해 본 발명의 구성 및 작용을 더욱 상세히 설명하기로 한다. 다만, 이는 본 발명의 바람직한 예시로 제시된 것이며 어떠한 의미로도 이에 의해 본 발명이 제한되는 것으로 해석될 수는 없다. Hereinafter, the configuration and operation of the present invention will be described in more detail with reference to preferred embodiments of the present invention. It is to be understood, however, that the same is by way of illustration and example only and is not to be construed in a limiting sense.
여기에 기재되지 않은 내용은 이 기술 분야에서 숙련된 자이면 충분히 기술적으로 유추할 수 있는 것이므로 그 설명을 생략하기로 한다.The contents not described here are sufficiently technically inferior to those skilled in the art, and a description thereof will be omitted.
제조예Manufacturing example 1 One
커피원두를 약 3.5 mesh의 크기로 분쇄한 후, 9 atm의 압력으로 열수 추출하여, 커피 원액을 제조하고 남은 부산물을 건조하여 커피박을 준비하였다.The coffee beans were pulverized to a size of about 3.5 mesh and then subjected to hot water extraction at a pressure of 9 atm to prepare a coffee concentrate, and the remaining by-products were dried to prepare a coffee bean.
제조예Manufacturing example 2 2
황금 뿌리 건조물을 약 3.5 mesh의 크기로 분쇄한 후, 1 atm의 압력으로 열수 추출하여, 황금 뿌리 추출물을 제조하고 남은 부산물을 건조하여 황금박을 준비하였다.The dried root of golden roots was pulverized to a size of about 3.5 mesh and subjected to hot water extraction at a pressure of 1 atm to prepare a golden root extract and the remaining by-products were dried to prepare a golden foil.
제조예Manufacturing example 3 3
감귤피 건조물을 약 1 mesh의 크기로 미세분말화한 후, 주정을 가한 후 여과하여 감귤피 추출물을 제조한 후, 상기 감귤피 추출물을 동결건조하여 분말형 감귤피 추출물을 준비하였다.The dried tangerine dried product was finely pulverized to a size of about 1 mesh. The dried tangerine dried product was filtered through a syringe and filtered to prepare a citrus peel extract. The citrus peel extract was lyophilized to prepare a powdery citrus peel extract.
제조예Manufacturing example 4 4
사과 열매를 믹서로 분쇄한 후, 1 atm의 압력으로 착즙하여, 사과 추출물을 제조하고 남은 부산물을 건조하여 사과박을 준비하였다.The apple fruit was pulverized with a mixer, and the mixture was squeezed at a pressure of 1 atm to prepare an apple extract. The remaining by-products were dried to prepare an apple pie.
제조예Manufacturing example 5 5
세네카 청포도(Vitis Labrusca)를 믹서로 분쇄한 후, 1 atm의 압력으로 착즙하여, 세네카 청포도 추출물을 제조하고 남은 부산물을 건조하여 세네카 청포도박을 준비하였다.The Vitis Labrusca was pulverized with a mixer, and the juice was squeezed at a pressure of 1 atm to prepare a Seneca citrus extract, and the remaining by-products were dried to prepare a Seneca citrus paste.
제조예Manufacturing example 6 6
매실의 씨앗을 제거한 후 믹서로 과육을 분쇄한 후, 1 atm의 압력으로 착즙하여, 매식 추출물을 제조하고 남은 부산물을 건조하여 매실박을 준비하였다.After the seeds of the plum were removed, the pulp was pulverized with a mixer, and the resulting mixture was squeezed at a pressure of 1 atm to prepare an insect extract, and the remaining by-products were dried to prepare a plum.
실시예Example 1 One
커피박 5g 및 황금박 0.5g을 혼합하고, 식용가능한 정제수 40ml를 첨가하여 혼합액을 제조하였다. 상기 혼합액에 감귤피 추출물 230ml 및 주정(99%) 30ml를 첨가 후 혼합 교반하여 천연 항균 조성물을 제조하였다.5 g of coffee grounds and 0.5 g of golden foil were mixed and 40 ml of edible water was added to prepare a mixed solution. 230 ml of citrus peel extract and 30 ml of ethanol (99%) were added to the mixture, followed by mixing and stirring to prepare a natural antimicrobial composition.
비교예Comparative Example 1 One
항균 활성이 있는 것으로 알려진 사과박 5.5g에 식용가능한 정제수 40ml를 첨가하여 혼합액을 제조하였다. 상기 혼합액에 사과박 추출물 230ml 및 에탄올(99%) 30ml를 첨가 후 혼합 교반하여 천연 항균 조성물을 제조하였다.A mixed solution was prepared by adding 40 ml of purified edible water to 5.5 g of apple pans known to have antimicrobial activity. 230 ml of the apple pomace extract and 30 ml of ethanol (99%) were added to the mixed solution, followed by mixing and stirring to prepare a natural antimicrobial composition.
비교예Comparative Example 2 2
항균 활성이 있는 것으로 알려진 세네카 청포도박 5.5g에 식용가능한 정제수 40ml를 첨가하여 혼합액을 제조하였다. 상기 혼합액에 세네카 청포도박 추출물 230ml 및 에탄올(99%) 30ml를 첨가 후 혼합 교반하여 천연 항균 조성물을 제조하였다.40 ml of water for edible use was added to 5.5 g of Seneca blue-green algae known to have antibacterial activity to prepare a mixed solution. To the mixture was added 230 ml of Seneca Blueberry extract and 30 ml of ethanol (99%), followed by mixing and stirring to prepare a natural antimicrobial composition.
비교예Comparative Example 3 3
항균 활성이 있는 것으로 알려진 매실박 5.5g에 식용가능한 정제수 40ml를 첨가하여 혼합액을 제조하였다. 상기 혼합액에 매실박 추출물 230ml 및 에탄올(99%) 30ml를 첨가 후 혼합 교반하여 천연 항균 조성물을 제조하였다.40 ml of edible water was added to 5.5 g of a plum mixture known to have antimicrobial activity to prepare a mixed solution. To the mixture was added 230 ml of the extract of mussel and 30 ml of ethanol (99%), followed by mixing and stirring to prepare a natural antimicrobial composition.
<항균 활성 평가>≪ Evaluation of antimicrobial activity &
실시예 1 및 비교예 1 내지 3에서 제조한 항균 조성물을 이용하여, 핸드프린팅 항균 평가 키트를 이용하여 항균력을 평가하였다. Using the antimicrobial compositions prepared in Example 1 and Comparative Examples 1 to 3, the antibacterial activity was evaluated using a hand printing antibacterial evaluation kit.
황색포도상구균, 대장균 및 일반세균용 핸드프린팅 항균 평가 키트를 각각 2개씩 준비한 후 1개의 키트에는 세정하기 전의 손을 접촉시키고, 다른 1개의 키트에는 실시예 1 및 비교예 1 내지 3의 항균 조성물 10ml를 스프레이 도포하여 세정한 손을 접촉시킨 후, 24시간 방치후 발생한 집락 수를 세어 하기 표 1에 표시하였다. 또한, 본 발명 실시예 1의 천연 항균 조성물에 대한 항균성 평가 결과를 도 3에 사진으로 표시하였다.Staphylococcus aureus, Escherichia coli, and a hand-printing antibacterial evaluation kit for general bacteria were prepared. Each kit was contacted with one hand before cleaning. In the other kit, 10 ml of the antimicrobial composition of Example 1 and Comparative Examples 1 to 3 And the number of colonies occurred after standing for 24 hours was counted. The results are shown in Table 1 below. ≪ tb > < TABLE > The antimicrobial activity of the natural antimicrobial composition of Example 1 of the present invention is shown in FIG. 3 as a photograph.
(TNTC : too numerous to count)(TNTC: too many to count)
상기 표 1의 결과를 통해 알 수 있는 바와 같이, 본 발명의 천연 항균 조성물은 식품 부산물을 이용하면서도 황색포도상구균, 대장균 및 일반세균에 대한 항균 활성이 비교예 1 내지 3에 비해 우수함을 확인하였다. As can be seen from the results shown in Table 1, the natural antimicrobial composition of the present invention was found to be superior in antibacterial activity against Staphylococcus aureus, Escherichia coli, and common bacteria, while using food byproducts, as compared with Comparative Examples 1 to 3.
또한, 본 발명의 천연 항균 조성물은 성분 전체가 천연 유래 성분으로 인체 무해하고, 환경 친화성이 우수함을 알 수 있다.In addition, the natural antimicrobial composition of the present invention is a natural-derived component as a whole, which is harmless to the human body and is excellent in environmental compatibility.
10: 황색포도상구균 키트 항균성 평가 결과
11: 세정전 12: 세정후
20: 대장균 키트 항균성 평가 결과
21: 세정전 22: 세정후
30: 일반세균 키트 항균성 평가 결과
31: 세정전 32: 세정후10: Antibacteriality evaluation result of Staphylococcus aureus kit
11: before cleaning 12: after cleaning
20: Antimicrobial activity of Escherichia coli kit
21: before cleaning 22: after cleaning
30: Antimicrobial activity of general bacterial kits
31: before cleaning 32: after cleaning
Claims (10)
A natural antimicrobial composition comprising coffee bean extract, citrus peel extract, golden foil extract and alcohol.
상기 천연 항균 조성물은 커피박 추출물 5 중량% 내지 15 중량%, 감귤피 추출물 65 중량% 내지 85 중량%, 황금박 추출물 1 중량% 내지 10 중량% 및 주정 5 중량% 내지 10 중량%를 포함하는 것인 천연 항균 조성물.
The method according to claim 1,
Wherein said natural antimicrobial composition comprises 5 to 15% by weight of a coffee bean extract, 65 to 85% by weight of a citrus peel extract, 1 to 10% by weight of a golden foil extract and 5 to 10% / RTI >
상기 황금박 추출물 및 커피박 추출물의 중량비는 1:5 내지 1:15인 천연 항균 조성물.
3. The method of claim 2,
Wherein the weight ratio of the golden foil extract to the coffee foil extract is 1: 5 to 1:15.
상기 주정은 사카로미세스 세레비시아(Saccharomyces cerevisiae)의 알코올발효에 의해 제조된 알코올 성분을 95% 내지 99%로 포함하는 것인 천연 항균 조성물.
The method according to claim 1,
Wherein the alcohol contains from 95% to 99% of an alcohol component produced by alcohol fermentation of Saccharomyces cerevisiae.
상기 천연 항균 조성물은 황색포도상구균 및 대장균에 대한 항균력을 갖고, 피부외용, 식품용 및 식기세정용 중 1종 이상인 천연 항균 조성물.
The method according to claim 1,
Wherein said natural antimicrobial composition has at least one kind of antimicrobial activity against Staphylococcus aureus and Escherichia coli, and for skin external use, food use, and tableware cleaning.
감귤피 추출물 및 주정을 혼합하여 제2혼합액을 제조하는 단계; 및
상기 제1혼합액 및 제2혼합액을 혼합하는 단계;를 포함하는 천연 항균 조성물 제조 방법.
Adding purified water to the coffee beans and the golden foil mixture to prepare a first mixed solution;
Preparing a second mixture liquid by mixing citrus peel extract and alcohol; And
And mixing the first mixed liquid and the second mixed liquid.
상기 혼합물 중 황금박 및 커피박의 중량비는 1:5 내지 1:15인 천연 항균 조성물 제조 방법.
The method according to claim 6,
Wherein the weight ratio of the golden foil to the coffee foil in the mixture is from 1: 5 to 1:15.
상기 천연 항균 조성물은 제1혼합액 10 중량% 내지 30 중량% 및 제2혼합액 70 중량% 내지 90 중량%를 포함하는 것인 천연 항균 조성물 제조 방법.
The method according to claim 6,
Wherein the natural antimicrobial composition comprises 10 wt% to 30 wt% of the first mixture and 70 wt% to 90 wt% of the second mixture.
상기 주정은 사카로미세스 세레비시아(Saccharomyces cerevisiae)의 알코올발효에 의해 제조된 알코올 성분을 95% 내지 99%로 포함하는 것인 천연 항균 조성물 제조 방법.
The method according to claim 6,
Wherein the alcohol contains 95 to 99% of an alcohol component produced by alcohol fermentation of Saccharomyces cerevisiae.
상기 천연 항균 조성물은 황색포도상구균 및 대장균에 대한 항균력을 갖고, 피부외용, 식품용 및 식기세정용 중 1종 이상인 천연 항균 조성물 제조 방법.
The method according to claim 6,
Wherein said natural antimicrobial composition has at least one kind of antimicrobial activity against Staphylococcus aureus and Escherichia coli, and is used for skin external use, food use, and tableware cleaning.
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Cited By (2)
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|---|---|---|---|---|
| KR102234814B1 (en) * | 2020-09-01 | 2021-04-01 | 주식회사 산내들에프에스 | Eco-friendly hand sanitizer containing rice snow extract and its manufacturing method |
| KR20210125203A (en) * | 2020-04-08 | 2021-10-18 | 정원철 | Antibacterial composition containing coffee waste extract |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06256104A (en) * | 1993-03-03 | 1994-09-13 | Honsyu Kosan Kk | Antibacterial action-sustaining disinfectant |
-
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06256104A (en) * | 1993-03-03 | 1994-09-13 | Honsyu Kosan Kk | Antibacterial action-sustaining disinfectant |
Non-Patent Citations (2)
| Title |
|---|
| Journal of the Korean Oil Chemists` Society, Vol.33, No.3, pp.606-613, 2016 * |
| 한국식품영양과학회지, 제30권, 제5호, pp.964-968, 2001 * |
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| KR20210125203A (en) * | 2020-04-08 | 2021-10-18 | 정원철 | Antibacterial composition containing coffee waste extract |
| KR102234814B1 (en) * | 2020-09-01 | 2021-04-01 | 주식회사 산내들에프에스 | Eco-friendly hand sanitizer containing rice snow extract and its manufacturing method |
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