KR20180032188A - Disinfectant composition, composition for blending disinfectant, method for manufacturing disinfectant composition, method of disinfection and disinfection kit - Google Patents

Abstract

Provided is a disinfection composition suitable for disinfecting cattle sheds by exhibiting disinfection and sterilizing effects against various pathogens without being frozon even when the disinfection composition is diluted with water under cold places (for example, at a temperature of -30-0°C) during winter. Moreover, provided are a composition for blending disinfectants, a method for producing the disinfection composition, a disinfection method, and a disinfection kit. To this end the disinfection composition is composed of at least one disinfection component selected from the group consisting of a fatty acid salt (A), a cryoprotective agent (B) containing polyvalent alcohol, a strong base (C), a disinfectant (D), and may additionally contain water (E).

Description

TECHNICAL FIELD The present invention relates to a disinfecting composition, a composition for blending a disinfectant, a method for producing the disinfectant composition, a disinfecting method, and a disinfection kit,

The present invention relates to a disinfecting composition, a composition for compounding a disinfectant, a method for producing and disinfecting the disinfecting composition using the composition for compounding the disinfectant, and a disinfection kit.

The disinfectant for use in an axial use is generally a disinfectant used in houses, houses and the like, and is generally used as an aqueous solution by diluting it to a predetermined concentration (for example, about 25 to 3000 times) (for example, Patent Document 1).

However, the disinfectant aqueous solution in which the disinfectant is diluted with water quickly freezes in a cold place where the freezing environment becomes a motive, so that the disinfecting effect is not sufficiently obtained. At present, effective disinfectants and disinfection methods which exhibit the disinfecting effect even in the motive cold regions are not enough, which is a problem. For example, non-patent document 1 suggests the use of methanol or the like in combination, but methanol is highly toxic and designated as a deleterious substance, so its use is not recommended.

On the other hand, there are known cryoprotectants for road or airport runways using acetic acid salts, alcohols and the like as cryoprotectants in cold regions (see, for example, Patent Document 2).

Japanese Patent No. 3624915 Japanese Patent Specification No. 2004-537611

National Livestock Health Hygiene Achievement Abstract (Ministry of Agriculture, Forestry and Fisheries), page 231, page 140, VIII-5 Livestock Technology "615. Review of the deadly virus effect of disinfectants at severe periods "and" 616. Review of disinfection methods under freezing conditions "

In view of the above problems of the prior art, the present invention can exert disinfection effects on various pathogens without being frozen even when diluted with water at a synchronous cold place (for example, -30 to 0 占 폚) A disinfecting composition, a composition for compounding a disinfectant, a method for producing and disinfecting the disinfectant composition using the composition for compounding a disinfectant, and a disinfecting kit.

The inventors of the present invention have found out a disinfecting composition capable of exhibiting disinfecting effect against various pathogens without freezing even when diluted with water in a synchronous cold place by combining a specific cryoprotective agent with a disinfecting component or a specific pH, And has reached the completion of the invention.

That is, the present invention is as follows.

(1) In the first aspect of the present invention,

(C) a strong base and (D) a disinfecting component, and further comprising (E) water, and further comprises (E) a water-insoluble antiseptic agent selected from the group consisting of (A) a fatty acid salt, (B) a cryoprotectant containing a polyhydric alcohol, .

(2) According to a second aspect of the present invention,

(E) at least one cryoprotectant selected from the group consisting of (A) a fatty acid salt and (B1) glycerin, and further comprising water.

(3) In a third aspect of the present invention,

(E) at least one disinfecting component selected from the group consisting of (C) a strong base and (D) a disinfectant, wherein at least one disinfecting component selected from the group consisting of (A) a fatty acid salt and (B1) glycerin, As a disinfecting composition which may further contain water,

(C) a strong base other than calcium hydroxide (Ca (OH) ₂ ) when the above-mentioned (A) fatty acid salt is the potassium salt of the acetic acid as the above-mentioned cryoprotectant.

(4) The disinfecting composition according to any one of (1) to (3), wherein the content of the cryoprotectant is not more than 65 mass% when (E) water is contained.

(5) The disinfecting composition according to any one of (1) to (4), which is for house disinfection.

(6) In a fourth aspect of the present invention,

(D) a disinfecting agent according to any one of the following compositions 1 to 4.

Composition 1: Composition comprising at least one cryoprotectant selected from the group consisting of (A) a fatty acid salt and (B) a polyhydric alcohol, (C) a strong base, and (E)

Composition 2: A composition comprising at least one cryoprotectant selected from the group consisting of (A) a fatty acid salt and (B) a polyhydric alcohol, wherein the composition further comprises (E) water, Excluded)

Composition 3: A composition comprising a cryoprotectant comprising (A) a fatty acid salt and (B) a polyhydric alcohol, wherein (E) a composition which may further comprise water (excluding the compositions 1 and 2)

Composition 4: Composition comprising (B1) glycerin, (E) Composition which may further contain water (except compositions 1 to 3)

(7) The composition according to (6), which is for house disinfection.

(8) A fifth aspect of the present invention is a method for producing a disinfecting composition, which comprises a step of combining a composition relating to the fourth aspect and (D) a disinfecting agent.

(9) The method for producing a disinfecting composition according to (8), wherein the disinfecting composition is a composition for disinfection of a house.

(10) The sixth aspect of the present invention is a disinfection method which further comprises a step of adding a disinfecting agent to the composition related to the fourth aspect (D), and further comprising diluting with water.

(11) A seventh aspect of the present invention relates to a composition comprising at least one cryoprotectant selected from the group consisting of (A) a fatty acid salt and (B) a polyhydric alcohol, (D) a disinfecting agent, (C) And (E) water. The disinfecting kit may further comprise at least one member selected from the group consisting of (E) water.

(12) The disinfection kit according to (11), wherein the disinfection kit is for indoor use.

The disinfecting composition of the present invention, the composition for compounding the disinfectant, and the disinfecting kit can be sterilized by disinfecting various pathogens without being frozen even when diluted with water at a synchronous cold place (for example, -30 to 0 캜) And is suitable for disinfection of barns.

INDUSTRIAL APPLICABILITY The method and the disinfecting method of the present invention can sterilize various pathogens without being frozen even when diluted with water in a synchronous cold place, and thus are suitable for disinfection of animals.

BRIEF DESCRIPTION OF DRAWINGS FIG. 1 is a graph showing the relationship between the concentration of a cryoprotectant and the freezing point in an aqueous solution. FIG.

Hereinafter, the embodiments of the present invention will be described in detail, but the present invention is not limited to the following embodiments, but can be appropriately modified within the scope of the object of the present invention.

<Disinfecting composition>

The disinfecting composition according to the first aspect comprises at least one disinfecting component selected from the group consisting of (A) a cryoprotectant comprising a fatty acid salt and (B) a polyhydric alcohol, (C) a strong base and (D) (E) water.

The disinfecting composition relating to the second aspect comprises at least one cryoprotectant selected from the group consisting of (A) a fatty acid salt and (B1) glycerin, and may further comprise (E) water and has a pH of 11 or higher.

The disinfecting composition according to the third aspect comprises at least one disinfecting agent selected from the group consisting of (A) at least one cryoprotectant selected from the group consisting of a fatty acid salt and (B1) glycerin, and (C) a strong base and (D) (E) a water-insoluble antioxidant composition,

(C) a strong base other than calcium hydroxide as the above-mentioned cryoprotectant when the above-mentioned (A) fatty acid salt is included and the (A) fatty acid salt is potassium acetate.

(Freezing agent)

In the disinfecting composition relating to the first to third aspects, the (A) fatty acid salt may be an alkali metal salt or an alkaline earth metal salt of a fatty acid having 1 to 5 carbon atoms, and may be an alkali metal salt or an alkaline earth metal salt of a fatty acid having 1 to 3 carbon atoms And more preferably an alkali metal salt or alkaline earth metal salt of a fatty acid having 1 or 2 carbon atoms.

Examples of the fatty acid in the fatty acid salt (A) include formic acid, acetic acid, propionic acid, butyric acid and the like, and formic acid or acetic acid is preferable.

Examples of the alkali metal salt or alkaline earth metal salt include sodium salt, potassium salt, magnesium salt, calcium salt, barium salt and the like, preferably sodium salt or potassium salt.

(A) specific examples of the fatty acid salt include potassium acetate, sodium acetate, magnesium acetate, calcium acetate, barium acetate, potassium formate, sodium formate, magnesium formate, calcium formate, barium formate, potassium propionate, sodium propionate, magnesium propionate, calcium propionate, Potassium propionate, potassium butyrate, sodium butyrate, magnesium butyrate, calcium butyrate, barium butyrate and the like are preferable, and potassium acetate, sodium acetate, potassium formate or sodium formate is preferable, and potassium acetate or sodium acetate is more preferable.

In the disinfecting composition related to the first aspect, the polyhydric alcohol (B) is not particularly limited as long as it is an alcohol compound having two or more hydroxyl groups (preferably two to four hydroxyl groups, more preferably two or three hydroxyl groups) 2 to 4 polyhydric alcohols, and a polyhydric alcohol having 3 carbon atoms is preferable.

Specific examples of the polyhydric alcohol (B) include (B1) glycerin, propylene glycol, ethylene glycol and butylene glycol, and (B1) glycerin or propylene glycol is preferable and (B1) glycerin is more preferable.

In the disinfecting composition related to the first to third aspects, the cryoprotectant may be used alone, but plural kinds of cryoprotectants may be used in combination.

Table 2 shows the relationship between an aqueous solution of potassium acetate and glycerin and the freezing point as an example of the relationship between the freezing inhibitor and the freezing point in the aqueous solution, and Table 2 shows the relationship between the glycerin aqueous solution and the freezing point.

1, the relationship between the concentration of the cryoprotectant in the aqueous solution and the freezing point is summarized in a graph.

With reference to Tables 1 and 2 and FIG. 1, in the dilution with water (E) so that the solidifying point of the disinfecting composition (aqueous solution) related to the first to third aspects is lower than the temperature expected in the use environment, The concentration of the cryoprotectant in the disinfecting composition associated with the sun of ~ 3 can be adjusted.

In the disinfecting composition related to the first to third aspects, the content of the above-mentioned cryoprotectant (when the cryoprotectant of plural kinds is used, the total content thereof) is (E) By mass or less. In the case of diluting with (E) water, the content of the cryoprotectant before dilution is more preferably 62% by mass or less, still more preferably 58% by mass or less, particularly preferably 55% by mass or less.

In the case of (E) water dilution, the content of the above-mentioned antifreezing agent after dilution is more preferably 60% by mass or less, still more preferably 50% by mass or less, still more preferably 45% by mass or less from the viewpoints of disinfection effect and freezing point Is particularly preferable.

(Disinfection component)

The disinfecting composition according to the first and third aspects comprises at least one disinfecting component selected from the group consisting of (C) a strong base and (D) a disinfectant.

Examples of the strong base (C) include potassium hydroxide, sodium hydroxide, calcium hydroxide and barium hydroxide, and potassium hydroxide or sodium hydroxide is preferable.

Thin lime is generally classified as a disinfectant, but in the present invention, (C) is a strong base.

In the disinfecting composition related to the first to third aspects, the strong base (C) may be used alone or in combination with a plurality of species.

In the disinfecting composition related to the first to third aspects, there is no particular limitation as long as the content of the strong base (C) (the total content when the plural kinds of strong bases are used) is not particularly limited so long as it does not impair the sterilizing effect of disinfection. More preferably 0.05 to 5% by mass, still more preferably 0.05 to 3% by mass, still more preferably 10% by mass or more, still more preferably 11% Is particularly preferable.

In addition, the disinfecting composition related to the second aspect is preferably at least pH 11, and more preferably at least pH 12, from the viewpoint of disinfection effectiveness. The method for achieving the pH in the disinfecting composition related to the second aspect is not particularly limited as long as the pH is at least 11, but may be achieved by containing, for example, (C) a strong base.

(D) disinfecting agents include disinfectants such as sodium carbonate, citric acid liquid, complex hypochlorous acid disinfectant, chlorine disinfectant, and reverse osmosis disinfectant.

The disinfecting composition related to the second aspect may contain (D) disinfecting agent.

In the disinfecting composition relating to the first to third aspects, (D) the disinfecting agent may be used alone, but plural kinds may be used in combination.

In the disinfecting composition relating to the first to third aspects, the content of the disinfecting agent (when the disinfecting agent of plural kinds is used) is not particularly limited as far as it does not impair the disinfecting effect of the disinfecting agent, but (E) When diluted, the content before dilution is preferably 0.01 to 25% by mass, more preferably 0.05 to 20% by mass, further preferably 0.1 to 18% by mass, more preferably 0.1 to 15% by mass desirable.

The disinfecting composition related to the first to third aspects may or may not contain (E) water.

It is also preferable that the disinfectant composition related to the first to third aspects is diluted with (E) water at the time of use, from the viewpoint of the transportability, the viewpoint of adjusting the solidifying point of the disinfectant composition before use, and the disinfecting effect. The dilution ratio is not particularly limited as long as it does not impair the above-mentioned point of view. For example, 1.2 to 100 times is preferable, 1.2 to 50 times is more preferable, and 1.2 to 25 times is more preferable.

The disinfecting composition related to the first to third aspects is used for disinfecting the environment (for example, for disinfecting the house, for disinfecting the fish, for food in kitchen, restaurant, food factory, etc.) ), And the like, but is preferably for environmental disinfection and more preferably for house disinfection.

In addition, the disinfecting composition related to the first to third aspects can be applied to all of various disinfection methods such as a dipping method, a cleaning method, a cleaning method, a rubbing method and a spraying method.

In addition, the disinfecting composition related to the first to third aspects may be used as a sanitizing sheet product by impregnating wet tissue, cotton wool, non-woven fabric, or the like.

&Lt; Composition for compounding disinfectant &gt;

The composition for compounding the disinfecting agent (D) related to the fourth aspect is any one of the following compositions 1 to 4.

Composition 1: Composition comprising at least one cryoprotectant selected from the group consisting of (A) a fatty acid salt and (B) a polyhydric alcohol, (C) a strong base, and (E)

Composition 2: A composition comprising at least one cryoprotectant selected from the group consisting of (A) a fatty acid salt and (B) a polyhydric alcohol, wherein the composition further comprises (E) water, Excluded)

Composition 3: A composition comprising a cryoprotectant comprising (A) a fatty acid salt and (B) a polyhydric alcohol, wherein the composition further comprises (E) water (excluding the compositions 1 and 2)

Composition 4: (B1) A composition comprising glycerin, which further comprises (E) water, wherein the compositions (excluding the compositions 1 to 3)

The compositions 1 to 4 may or may not contain (E) water.

From the viewpoint of transportability and from the viewpoint of adjusting the solidifying point of the disinfecting composition before use, it is also preferable to use (E) diluted with water at the time of use. The dilution ratio is not particularly limited as long as it does not impair the above-mentioned point of view. For example, 1.2 to 100 times is preferable, 1.2 to 50 times is more preferable, and 1.2 to 25 times is more preferable.

Examples of the disinfectant (D) compounded with the composition related to the fourth aspect include the same disinfectants as the disinfectant (D) in the disinfecting composition related to the first to third aspects, and the disinfecting composition related to the first to third aspects .

Examples of the fatty acid salt (A) in the compositions 1 to 3 include the same ones as the fatty acid salt (A) in the disinfecting composition related to the first to third aspects, and the fatty acid salt (A) It is the same as the content in the sun-related disinfecting composition.

Examples of the polyhydric alcohol (B) in the compositions 1 to 3 include the same polyhydric alcohols as the polyhydric alcohol (B) in the disinfecting composition related to the first aspect, and the polyhydric alcohol (B) The content of (B1) glycerin is the same as that of the disinfecting composition related to the first to third aspects.

The strong base (C) in the composition 1 is the same as the strong base (C) in the disinfecting composition related to the first and third aspects, and as the content of the strong base (C) in the composition 1, It is the same as the content in the sun-related disinfecting composition.

The composition related to the fourth aspect can be used as a disinfecting composition by mixing any disinfectant (D), even in a synchronous cold region, even when diluted with water, without freezing. The disinfecting composition obtained by mixing the disinfecting agent (D) can be applied to all the disinfecting methods such as dipping method, cleansing method, washing method, rinsing method and spraying method.

The composition related to the fourth aspect is applicable for environmental disinfection and domestic use, but is preferably for environmental disinfection, and more preferably for house disinfection.

&Lt; Preparation method of disinfecting composition &gt;

The method for producing the disinfecting composition according to the fifth aspect includes the step of combining the composition related to the fourth aspect and the disinfecting agent (D).

The manufacturing method of the disinfecting composition related to the fifth aspect does not need to further include a step of diluting with (E) water. However, from the viewpoint of transportability, the point of adjusting the solidifying point of the disinfecting composition before use, and the disinfecting effect , And (E) water. The dilution ratio is not particularly limited as long as it does not impair the above-mentioned point of view. For example, 1.2 to 100 times is preferable, 1.2 to 50 times is more preferable, and 1.2 to 25 times is more preferable.

The composition relating to the fourth aspect may be diluted with (E) water, then (D) a disinfectant may be compounded, (D) the disinfectant may be diluted with (E) water, The composition relating to the fourth aspect and (D) disinfecting agent may be blended and then (E) diluted with water.

The manufactured disinfecting composition can be used for environmental disinfection and domestic use, but is preferably for environmental disinfection, and more preferably for house disinfection.

<Disinfection method>

The disinfecting method related to the sixth aspect includes a step of compounding (D) a disinfecting agent into the composition related to the fourth aspect, and the disinfecting composition is prepared by the above process.

The method of disinfecting in connection with the sixth aspect further includes a step of applying the disinfecting composition prepared by the above process to a disinfection object (housing, fish, kitchen, restaurant, food factory, tableware, food container, etc.).

As the method of application, all of the various disinfecting methods such as dipping method, cleansing method, washing method, chewing method and spraying method can be applied.

In addition, the disinfecting method related to the sixth aspect may or may not further include a step of diluting with (E) water. However, from the viewpoint of transportability, the point of adjusting the solidifying point of the composition before use, and the disinfecting effect E) water as a diluent. The dilution ratio is not particularly limited as long as it does not impair the above-mentioned point of view. For example, 1.2 to 100 times is preferable, 1.2 to 50 times is more preferable, and 1.2 to 25 times is more preferable.

<Disinfection kit>

The disinfecting kit according to the seventh aspect of the present invention comprises a composition comprising at least one cryoprotectant selected from the group consisting of (A) a fatty acid salt and (B) a polyhydric alcohol, (D) a disinfecting agent, (C) E) water may be further included.

An embodiment of the disinfecting kit according to the seventh aspect is a composition comprising at least one cryoprotectant selected from the group consisting of (A) a fatty acid salt and (B) a polyhydric alcohol, (D) A disinfecting kit comprising a composition containing the above-mentioned cryoprotectant and (D) a disinfecting agent in combination. It is preferable that the disinfecting kit is further diluted with water (E) at the time of use, from the viewpoint of transportability, from the viewpoint of adjusting the solidifying point of the disinfecting kit before use and from the viewpoint of adjusting the disinfecting effect. The dilution ratio is not particularly limited so long as it does not impair the above viewpoint. For example, it may be 1.2 to 100 times, preferably 1.2 to 50 times, and more preferably 1.2 to 25 times.

(A) a fatty acid salt, (B) a polyhydric alcohol, (C) a strong base, (D) a disinfectant in the disinfecting composition relating to the first to third aspects, (A) a fatty acid salt, (B) a polyhydric alcohol, (C) a strong base, (D) a fatty acid salt in a disinfecting kit related to the seventh aspect, The content of the disinfecting agent is the same as that of the disinfecting composition related to the first to third aspects.

The disinfecting kit related to the seventh aspect is applicable for environmental disinfection and domestic use, but is preferably for environmental disinfection and more preferably for house disinfection.

[ Example ]

Hereinafter, the present invention will be described in more detail with reference to examples, but the scope of the present invention is not limited to these examples.

<Test 1 (verification of freezing condition)>

A1) Aqueous solutions of various compositions (disinfecting compositions of Comparative Examples 1 to 7 and Examples 1 to 15) were prepared.

In Examples 1 to 13, various disinfectant solutions (D) were prepared, and then diluted with an aqueous solution of potassium acetate, glycerin and potassium hydroxide to obtain the composition ratios (mass%) shown in Table 3.

A2) 2 mL of the above A1) was put in a chalet.

A3) The chalet of A2) was placed in a freezer in an environment of -20 占 폚 and cooled.

A4) The chalet of A3) was taken out of the freezer after 24 hours from the start of cooling.

A5) Whether or not the aqueous solution was frozen was visually confirmed.

(Judgment method)

The frozen state was frozen to determine whether the solid or sherbet state was frozen (X), and the liquid phase was judged to be freezing (O).

The results of the verification of the frozen state under various freezing conditions (-20 캜) are shown in Table 3 below.

As is apparent from the results shown in Table 3, all of Comparative Examples 1 to 7, which were free from the cryoprotectant, were found to be frozen under a freezing environment (-20 ° C).

On the other hand, all of Examples 1 to 15 containing a cryoprotectant were found not to be frozen in a freezing environment (-20 캜).

&Lt; Test 2 (Verification of disinfection effectiveness against Salmonella) &gt;

B1) 2 mL of the above A1) of Test 1 was put in a chalet.

B2) The chalet of B1) was placed in a freezer in an environment of -20 ° C and cooled.

B3) The broth of the above B2) was added with the fermentation broth adjusted to McPhyland 4.

B4) for 5 minutes under an environment of -20 占 폚.

B5) diluted rapidly with physiological saline.

B6) taken out from the freezer.

B7) The viable cell count was measured.

Here, the McFarland 4 is a method for estimating the number of viable bacteria in the bacterial solution from the turbidity, and 4 is the number of the McFarland standard turbidity.

(Judgment method)

The sterilization effect of sterilization was evaluated in comparison with the number of living cells in tap water at room temperature (20 ° C). , The case where the number of bacteria was decreased to 1/10 or less, the case where the decrease of the number of bacteria was less than 1/10 was rated &quot; &quot;

Table 4 shows the results of verifying the disinfection effect of Salmonella Typhimurium (ST) under various freezing conditions (-20 ° C).

As is clear from the results shown in Table 4, the samples of Comparative Examples 1 to 7 could not be verified because they were frozen.

On the other hand, it can be seen that Examples 1 to 13 all exhibit disinfection effect against ST under a freezing environment (-20 ° C). It can be seen that Examples 1, 2, 4 to 8, and 10 to 13 are particularly excellent in disinfection effect against ST.

<Test 3 (Verification of disinfection effect for each pathogen)>

C2) 2 mL of the above A1) of Test 1 was put in a chalet.

C3) The chalet of C2) was placed in a freezer in an environment of -20 캜 and cooled.

C4) Various hospital fluid (IBRV / BCV / SIV / BVDV / AdV-7) was added to the chalet of C3).

Here, IBRV is a bovine infectious non-lytic virus, BCV is a bovine coronavirus, SIV is a swine influenza virus, BVDV is a bovine viral diarrhea virus, and AdV-7 is a small adenovirus type 7.

C5) -20 &lt; 0 &gt; C for 5 minutes.

C6) 96-well microplate and cultured cells for various pathogens were used and the 50% infection end point (TCID ₅₀ ) was measured using the cytopathic effect (CPE) as an index.

MDBK-SY cells (small intestine-derived cells) for BVDV, MDBK-SY cells (small intestine-derived cells) for BVDV, Kidney-derived cell line), and adenovascular endothelial cells for AdV-7.

C7) The activity of the pathogen was calculated from the C6).

(Judgment method)

The disinfection effect was evaluated by the potency of the pathogen in comparison with the potency of the pathogen in tap water at room temperature. The case where the titer of the pathogen was reduced to 1/10 or less was designated as &quot; &quot;, the case where the reduction of the titer of the pathogen was less than 1/10 was designated as &quot;

Table 5 shows the results of verifying the disinfection effect against various pathogens (IBRV / BCV / SIV / BVDV / AdV-7) under various freezing conditions of composition (-20 캜).

As evident from the results shown in Table 5, the samples of Comparative Examples 1 to 7 could not be verified because they were frozen.

On the other hand, in all of Examples 1 to 13, sterilization effect of at least one of various pathogens (IBRV / BCV / SIV / BVDV / AdV-7) was observed under the freezing environment (-20 ° C). It can be seen that Examples 4, 5, 10, and 11 using a complex hypochlorous acid-based or chlorine-based disinfectant exhibit excellent disinfection effect against any pathogenic agent (IBRV / BCV / SIV / BVDV / AdV-7).

Claims (10)

(C) a disinfecting component which is a strong base, more than 0.1% by mass but not more than 15% by mass (excluding 2% by mass), (E) a cryoprotectant comprising (A) a fatty acid salt and (B) a polyhydric alcohol, Wherein the strong base (C) is at least one strong base selected from the group consisting of potassium hydroxide and sodium hydroxide. In claim 1,
(E) water, the content of the cryoprotectant is 65 mass% or less. In claim 1 or 2,
Disinfecting composition for barn disinfection. (D) a composition having a pH of 12 or higher for compounding a disinfectant,
At least one strong base selected from the group consisting of (A) a fatty acid salt and (B) a polyhydric alcohol, and (C) at least one strong base selected from the group consisting of potassium hydroxide and sodium hydroxide in an amount of not less than 0.1% by mass but not more than 15% (E) &lt; / RTI &gt; water. In claim 4,
A composition for disinfecting a house. A method for producing a disinfecting composition comprising the step of combining the composition of claim 4 or claim 5 with a disinfecting agent. In claim 6,
Wherein the disinfecting composition is a composition for disinfecting a house. (D) a step of adding a disinfecting agent to the composition of claim 4 or 5, and further comprising a step of diluting with water, and further comprising a step of applying the disinfecting composition prepared by said step to a house How to disinfect. At least one strong base selected from the group consisting of (A) a fatty acid salt and (B) a polyhydric alcohol, and (C) at least one strong base selected from the group consisting of potassium hydroxide and sodium hydroxide in an amount of not less than 0.1% by mass but not more than 15% (D) a disinfecting agent, and (E) water. In claim 9,
Disinfection kit for disinfection of barn.

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