JP6144397B1 - Disinfecting composition, composition for incorporating disinfectant, disinfecting composition manufacturing method, disinfecting method, and disinfecting kit - Google Patents
Disinfecting composition, composition for incorporating disinfectant, disinfecting composition manufacturing method, disinfecting method, and disinfecting kit Download PDFInfo
- Publication number
- JP6144397B1 JP6144397B1 JP2016184301A JP2016184301A JP6144397B1 JP 6144397 B1 JP6144397 B1 JP 6144397B1 JP 2016184301 A JP2016184301 A JP 2016184301A JP 2016184301 A JP2016184301 A JP 2016184301A JP 6144397 B1 JP6144397 B1 JP 6144397B1
- Authority
- JP
- Japan
- Prior art keywords
- disinfecting
- composition
- disinfectant
- mass
- disinfection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 160
- 230000000249 desinfective effect Effects 0.000 title claims abstract description 116
- 239000000645 desinfectant Substances 0.000 title claims abstract description 57
- 238000000034 method Methods 0.000 title claims abstract description 36
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 48
- -1 fatty acid salt Chemical class 0.000 claims abstract description 41
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 35
- 229930195729 fatty acid Natural products 0.000 claims abstract description 35
- 239000000194 fatty acid Substances 0.000 claims abstract description 35
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 31
- 150000005846 sugar alcohols Polymers 0.000 claims abstract description 24
- 230000001954 sterilising effect Effects 0.000 claims abstract description 22
- 238000002156 mixing Methods 0.000 claims abstract description 14
- 238000004659 sterilization and disinfection Methods 0.000 claims description 71
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 18
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 15
- 238000007865 diluting Methods 0.000 claims description 7
- 238000007710 freezing Methods 0.000 abstract description 29
- 230000008014 freezing Effects 0.000 abstract description 28
- 244000052769 pathogen Species 0.000 abstract description 16
- 235000002639 sodium chloride Nutrition 0.000 description 36
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 27
- 239000002585 base Substances 0.000 description 23
- 230000000694 effects Effects 0.000 description 16
- SCVFZCLFOSHCOH-UHFFFAOYSA-M potassium acetate Chemical group [K+].CC([O-])=O SCVFZCLFOSHCOH-UHFFFAOYSA-M 0.000 description 14
- 235000011187 glycerol Nutrition 0.000 description 13
- 239000007864 aqueous solution Substances 0.000 description 10
- 210000004027 cell Anatomy 0.000 description 9
- 239000002577 cryoprotective agent Substances 0.000 description 9
- 238000010790 dilution Methods 0.000 description 9
- 239000012895 dilution Substances 0.000 description 9
- 230000007613 environmental effect Effects 0.000 description 8
- 230000001717 pathogenic effect Effects 0.000 description 8
- 241000711443 Bovine coronavirus Species 0.000 description 7
- 241000710780 Bovine viral diarrhea virus 1 Species 0.000 description 7
- 235000011056 potassium acetate Nutrition 0.000 description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
- PPBOKXIGFIBOGK-BDTUAEFFSA-N bvdv Chemical compound C([C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)C1=CN=CN1 PPBOKXIGFIBOGK-BDTUAEFFSA-N 0.000 description 6
- 244000144972 livestock Species 0.000 description 6
- 238000012795 verification Methods 0.000 description 6
- 239000000243 solution Substances 0.000 description 5
- 241000283690 Bos taurus Species 0.000 description 4
- 241000293869 Salmonella enterica subsp. enterica serovar Typhimurium Species 0.000 description 4
- 229910052783 alkali metal Inorganic materials 0.000 description 4
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 4
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 4
- 239000000920 calcium hydroxide Substances 0.000 description 4
- 235000011116 calcium hydroxide Nutrition 0.000 description 4
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 4
- 239000008399 tap water Substances 0.000 description 4
- 235000020679 tap water Nutrition 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 238000013329 compounding Methods 0.000 description 3
- 238000007598 dipping method Methods 0.000 description 3
- 150000004665 fatty acids Chemical class 0.000 description 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 235000011118 potassium hydroxide Nutrition 0.000 description 3
- 239000001632 sodium acetate Substances 0.000 description 3
- 235000017281 sodium acetate Nutrition 0.000 description 3
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 2
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- 239000004280 Sodium formate Substances 0.000 description 2
- 235000011054 acetic acid Nutrition 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- 239000000460 chlorine Substances 0.000 description 2
- 229910052801 chlorine Inorganic materials 0.000 description 2
- 230000000120 cytopathologic effect Effects 0.000 description 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 2
- 235000019253 formic acid Nutrition 0.000 description 2
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical compound ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 description 2
- 230000001771 impaired effect Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 2
- WFIZEGIEIOHZCP-UHFFFAOYSA-M potassium formate Chemical compound [K+].[O-]C=O WFIZEGIEIOHZCP-UHFFFAOYSA-M 0.000 description 2
- HLBBKKJFGFRGMU-UHFFFAOYSA-M sodium formate Chemical compound [Na+].[O-]C=O HLBBKKJFGFRGMU-UHFFFAOYSA-M 0.000 description 2
- 235000019254 sodium formate Nutrition 0.000 description 2
- 159000000000 sodium salts Chemical class 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- JXPHLUCMHXXHEJ-UHFFFAOYSA-N 2-(aminomethyl)-4-bromoaniline Chemical compound NCC1=CC(Br)=CC=C1N JXPHLUCMHXXHEJ-UHFFFAOYSA-N 0.000 description 1
- OURWKHLDAVYMGO-UHFFFAOYSA-N 7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid Chemical compound C=1C=NC2=C(C(=O)O)C=NN2C=1C1=CC=CS1 OURWKHLDAVYMGO-UHFFFAOYSA-N 0.000 description 1
- 241000701098 Bovine adenovirus 7 Species 0.000 description 1
- CBOCVOKPQGJKKJ-UHFFFAOYSA-L Calcium formate Chemical compound [Ca+2].[O-]C=O.[O-]C=O CBOCVOKPQGJKKJ-UHFFFAOYSA-L 0.000 description 1
- BCZXFFBUYPCTSJ-UHFFFAOYSA-L Calcium propionate Chemical compound [Ca+2].CCC([O-])=O.CCC([O-])=O BCZXFFBUYPCTSJ-UHFFFAOYSA-L 0.000 description 1
- 241000282465 Canis Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010051497 Rhinotracheitis Diseases 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 241000725681 Swine influenza virus Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 150000001242 acetic acid derivatives Chemical class 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- ITHZDDVSAWDQPZ-UHFFFAOYSA-L barium acetate Chemical compound [Ba+2].CC([O-])=O.CC([O-])=O ITHZDDVSAWDQPZ-UHFFFAOYSA-L 0.000 description 1
- RQPZNWPYLFFXCP-UHFFFAOYSA-L barium dihydroxide Chemical compound [OH-].[OH-].[Ba+2] RQPZNWPYLFFXCP-UHFFFAOYSA-L 0.000 description 1
- 229910001863 barium hydroxide Inorganic materials 0.000 description 1
- 159000000009 barium salts Chemical class 0.000 description 1
- AESMDVCWMVZFRQ-UHFFFAOYSA-L barium(2+);butanoate Chemical compound [Ba+2].CCCC([O-])=O.CCCC([O-])=O AESMDVCWMVZFRQ-UHFFFAOYSA-L 0.000 description 1
- UXFOSWFWQAUFFZ-UHFFFAOYSA-L barium(2+);diformate Chemical compound [Ba+2].[O-]C=O.[O-]C=O UXFOSWFWQAUFFZ-UHFFFAOYSA-L 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- VSGNNIFQASZAOI-UHFFFAOYSA-L calcium acetate Chemical compound [Ca+2].CC([O-])=O.CC([O-])=O VSGNNIFQASZAOI-UHFFFAOYSA-L 0.000 description 1
- 239000001639 calcium acetate Substances 0.000 description 1
- 235000011092 calcium acetate Nutrition 0.000 description 1
- 229960005147 calcium acetate Drugs 0.000 description 1
- 239000004281 calcium formate Substances 0.000 description 1
- 235000019255 calcium formate Nutrition 0.000 description 1
- 229940044172 calcium formate Drugs 0.000 description 1
- 239000004330 calcium propionate Substances 0.000 description 1
- 235000010331 calcium propionate Nutrition 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- FYPVXEILSNEKOO-UHFFFAOYSA-L calcium;butanoate Chemical compound [Ca+2].CCCC([O-])=O.CCCC([O-])=O FYPVXEILSNEKOO-UHFFFAOYSA-L 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 210000004748 cultured cell Anatomy 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000002939 deleterious effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- UEGPKNKPLBYCNK-UHFFFAOYSA-L magnesium acetate Chemical compound [Mg+2].CC([O-])=O.CC([O-])=O UEGPKNKPLBYCNK-UHFFFAOYSA-L 0.000 description 1
- 235000011285 magnesium acetate Nutrition 0.000 description 1
- 239000011654 magnesium acetate Substances 0.000 description 1
- 229940069446 magnesium acetate Drugs 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
- GMDNUWQNDQDBNQ-UHFFFAOYSA-L magnesium;diformate Chemical compound [Mg+2].[O-]C=O.[O-]C=O GMDNUWQNDQDBNQ-UHFFFAOYSA-L 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- BWILYWWHXDGKQA-UHFFFAOYSA-M potassium propanoate Chemical compound [K+].CCC([O-])=O BWILYWWHXDGKQA-UHFFFAOYSA-M 0.000 description 1
- 239000004331 potassium propionate Substances 0.000 description 1
- 235000010332 potassium propionate Nutrition 0.000 description 1
- RWMKSKOZLCXHOK-UHFFFAOYSA-M potassium;butanoate Chemical compound [K+].CCCC([O-])=O RWMKSKOZLCXHOK-UHFFFAOYSA-M 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- MFBOGIVSZKQAPD-UHFFFAOYSA-M sodium butyrate Chemical compound [Na+].CCCC([O-])=O MFBOGIVSZKQAPD-UHFFFAOYSA-M 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- JXKPEJDQGNYQSM-UHFFFAOYSA-M sodium propionate Chemical compound [Na+].CCC([O-])=O JXKPEJDQGNYQSM-UHFFFAOYSA-M 0.000 description 1
- 239000004324 sodium propionate Substances 0.000 description 1
- 235000010334 sodium propionate Nutrition 0.000 description 1
- 229960003212 sodium propionate Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 210000003556 vascular endothelial cell Anatomy 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/0047—Air-conditioning, e.g. ventilation, of animal housings
- A01K1/0082—Water misting or cooling systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/08—Alkali metal chlorides; Alkaline earth metal chlorides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Agronomy & Crop Science (AREA)
- Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
【課題】冬期の寒冷地（例えば、−３０〜０℃）において、消毒組成物を水で希釈した場合であっても凍結することなく、各種病原体に対して消毒殺菌効果を発揮することができ、畜舎消毒用として好適な、消毒組成物、消毒剤を配合するための組成物、上記消毒組成物の製造方法、消毒方法、及び消毒キットを提供すること。【解決手段】（Ａ）脂肪酸塩及び（Ｂ）多価アルコールを含む凍結防止剤と、（Ｃ）強塩基及び（Ｄ）消毒剤よりなる群から選択される少なくとも１つの消毒成分とを含み、（Ｅ）水を更に含んでいてもよい消毒組成物。【選択図】なしIn a cold region in winter (for example, −30 to 0 ° C.), even when the disinfecting composition is diluted with water, it can exhibit disinfecting and sterilizing effects against various pathogens without freezing. To provide a disinfecting composition, a composition for blending a disinfectant, a method for producing the disinfecting composition, a disinfecting method, and a disinfecting kit suitable for disinfecting barns. An antifreezing agent comprising (A) a fatty acid salt and (B) a polyhydric alcohol, and (C) at least one disinfecting component selected from the group consisting of a strong base and (D) a disinfectant, (E) The disinfecting composition which may further contain water. [Selection figure] None
Description
本発明は、消毒組成物、消毒剤を配合するための組成物、消毒剤を配合するための上記組成物を用いた消毒組成物の製造方法及び消毒方法、並びに消毒キットに関する。 The present invention relates to a disinfecting composition, a composition for blending a disinfectant, a method for producing and disinfecting a disinfecting composition using the composition for blending a disinfectant, and a disinfecting kit.
畜舎用消毒剤は、一般的に畜舎、鶏舎等で使用されている消毒剤であり、一般的に、所定の濃度に希釈（例えば、２５〜３０００倍程度）して水溶液として使用される（例えば、特許文献１）。
しかしながら、凍結環境になる冬期の寒冷地においては、消毒剤を水で希釈した消毒剤水溶液はすぐに凍ってしまい消毒効果が十分に得られない。現在のところ、冬期の寒冷地でも消毒効果を発揮する有効な消毒剤及び消毒方法が少なく問題になっている。例えば、非特許文献１において、メタノール等の混合使用が提案されているが、メタノールは毒性が高く劇物指定されており、使用はあまり推奨されない。
一方、寒冷地における凍結防止剤として、酢酸塩、アルコール類等を用いた道路用又は空港滑走路用凍結防止剤等が知られている（例えば、特許文献２）。
The disinfectant for barns is a disinfectant generally used in livestock houses, poultry houses, etc., and is generally used as an aqueous solution after being diluted to a predetermined concentration (for example, about 25 to 3000 times) (for example, Patent Document 1).
However, in a cold region in winter when the environment is frozen, a disinfectant aqueous solution obtained by diluting a disinfectant with water freezes quickly and a sufficient disinfection effect cannot be obtained. At present, there are few effective disinfectants and disinfecting methods that exert a disinfecting effect even in cold regions in winter, which is a problem. For example, in Non-Patent Document 1, the use of a mixture of methanol or the like is proposed, but methanol is highly toxic and has been designated as a deleterious substance, and its use is not recommended.
On the other hand, antifreezing agents for roads or airport runways using acetates, alcohols and the like are known as antifreezing agents in cold regions (for example, Patent Document 2).
上記従来技術の問題に鑑み、本発明は、冬期の寒冷地（例えば、−３０〜０℃）において、水で希釈した場合であっても凍結することなく、各種病原体に対して消毒殺菌効果を発揮することができ、畜舎消毒用として好適な、消毒組成物、消毒剤を配合するための組成物、消毒剤を配合するための上記組成物を用いた消毒組成物の製造方法及び消毒方法、並びに消毒キットの提供を目的とする。 In view of the above-mentioned problems of the prior art, the present invention has a disinfecting and sterilizing effect against various pathogens in a cold region in winter (for example, −30 to 0 ° C.) without freezing even when diluted with water. Disinfecting composition suitable for use in barn disinfection, composition for compounding disinfectant, method for producing disinfecting composition and disinfecting method using the above composition for compounding disinfectant, The purpose is to provide a disinfection kit.
本発明者らは、特定の凍結防止剤と、消毒成分又は特定のｐＨとを組み合わせることにより、冬期の寒冷地において、水で希釈した場合であっても凍結することなく、各種病原体に対して消毒殺菌効果を発揮することができる消毒組成物を見出し、本発明を完成するに至った。
すなわち、本発明は以下の通りである。
By combining a specific anti-freezing agent and a disinfecting component or a specific pH, the present inventors can prevent various pathogens without freezing even when diluted with water in cold regions in winter. The present inventors have found a disinfecting composition capable of exhibiting a disinfecting and sterilizing effect and have completed the present invention.
That is, the present invention is as follows.
（１）本発明の第１の態様は、
（Ａ）脂肪酸塩及び（Ｂ）多価アルコールを含む凍結防止剤と、（Ｃ）強塩基及び（Ｄ）消毒剤よりなる群から選択される少なくとも１つの消毒成分とを含み、（Ｅ）水を更に含んでいてもよい消毒組成物である。
(1) The first aspect of the present invention is:
(E) water containing (A) fatty acid salt and (B) antifreezing agent containing polyhydric alcohol, (C) at least one disinfecting component selected from the group consisting of strong base and (D) disinfectant The disinfecting composition may further contain.
（２）本発明の第２の態様は、
（Ａ）脂肪酸塩及び（Ｂ１）グリセリンよりなる群から選択される少なくとも１つの凍結防止剤を含み、（Ｅ）水を更に含んでいてもよいｐＨ１１以上の消毒組成物である。
(2) The second aspect of the present invention is:
(A) A disinfecting composition having a pH of 11 or more, which contains at least one antifreezing agent selected from the group consisting of a fatty acid salt and (B1) glycerin, and may further contain (E) water.
（３）本発明の第３の態様は、
（Ａ）脂肪酸塩及び（Ｂ１）グリセリンよりなる群から選択される少なくとも１つの凍結防止剤、並びに（Ｃ）強塩基及び（Ｄ）消毒剤よりなる群から選択される少なくとも１つの消毒成分を含み、（Ｅ）水を更に含んでいてもよい消毒組成物であって、
上記凍結防止剤として上記（Ａ）脂肪酸塩を含み、かつ該（Ａ）脂肪酸塩が酢酸カリウムのとき、消石灰（Ｃａ（ＯＨ）２）以外の上記（Ｃ）強塩基を含む、消毒組成物である。
（４）（Ｅ）水を含むとき、上記凍結防止剤の含有量が６５質量％以下である、（１）〜（３）のいずれか１項に記載の消毒組成物。
（５）畜舎消毒用である、（１）〜（４）のいずれか１項に記載の消毒組成物。
(3) The third aspect of the present invention is:
(A) a fatty acid salt and (B1) at least one cryoprotectant selected from the group consisting of glycerin, and (C) at least one antiseptic component selected from the group consisting of a strong base and (D) a disinfectant (E) a disinfecting composition that may further contain water,
A disinfecting composition comprising the (A) fatty acid salt as the antifreezing agent, and the (C) strong base other than slaked lime (Ca (OH) 2 ) when the (A) fatty acid salt is potassium acetate. is there.
(4) The disinfecting composition according to any one of (1) to (3), wherein when (E) water is contained, the content of the antifreezing agent is 65% by mass or less.
(5) The disinfecting composition according to any one of (1) to (4), wherein the disinfecting composition is used for disinfecting barns.
（６）本発明の第４の態様は、
（Ｄ）消毒剤を配合するための組成物であって、下記組成物１〜４のいずれかである、組成物である。
組成物１：（Ａ）脂肪酸塩及び（Ｂ）多価アルコールよりなる群から選択される少なくとも１つの凍結防止剤と、（Ｃ）強塩基とを含み、（Ｅ）水を更に含んでいてもよい組成物
組成物２：（Ａ）脂肪酸塩及び（Ｂ）多価アルコールよりなる群から選択される少なくとも１つの凍結防止剤を含み、（Ｅ）水を更に含んでいてもよいｐＨ１１以上の組成物（ただし、上記組成物１を除く。）
組成物３：（Ａ）脂肪酸塩及び（Ｂ）多価アルコールを含む凍結防止剤を含む組成物であって、更に（Ｅ）水を含んでいてもよい組成物（ただし、上記組成物１及び２を除く。）
組成物４：（Ｂ１）グリセリンを含む組成物であって、更に（Ｅ）水を含んでいてもよい組成物（ただし、上記組成物１〜３を除く。）
（７）畜舎消毒用である、（６）に記載の組成物。
(6) The fourth aspect of the present invention is
(D) A composition for blending a disinfectant, which is one of the following compositions 1 to 4.
Composition 1: (A) a fatty acid salt and (B) at least one cryoprotectant selected from the group consisting of polyhydric alcohols, (C) a strong base, and (E) a water further Good Composition Composition 2: A composition having a pH of 11 or more, which contains (A) a fatty acid salt and (B) at least one antifreezing agent selected from the group consisting of polyhydric alcohols, and (E) may further contain water. Product (excluding Composition 1 above)
Composition 3: (A) a composition containing a fatty acid salt and (B) an antifreezing agent containing a polyhydric alcohol, and (E) a composition which may further contain water (however, the above composition 1 and (Excluding 2)
Composition 4: (B1) A composition containing glycerin, which may further contain (E) water (excluding the above compositions 1 to 3).
(7) The composition according to (6), which is for sterilization of barns.
（８）本発明の第５の態様は、第４の態様に係る組成物と（Ｄ）消毒剤とを配合する工程を含む、消毒組成物の製造方法である。
（９）上記消毒組成物が畜舎消毒用組成物である、（８）に記載の消毒組成物の製造方法。
(8) A fifth aspect of the present invention is a method for producing a disinfecting composition, comprising a step of blending the composition according to the fourth aspect and (D) a disinfectant.
(9) The method for producing a disinfecting composition according to (8), wherein the disinfecting composition is a composition for disinfecting barns.
（１０）本発明の第６の態様は、第４の態様に係る組成物に（Ｄ）消毒剤を配合する工程を含み、水で希釈する工程を更に含んでいてもよい消毒方法である。 (10) The sixth aspect of the present invention is a disinfection method that includes a step (D) of adding a disinfectant to the composition according to the fourth embodiment, and may further include a step of diluting with water.
（１１）本発明の第７の態様は、（Ａ）脂肪酸塩及び（Ｂ）多価アルコールよりなる群から選択される少なくとも１つの凍結防止剤を含む組成物と、（Ｄ）消毒剤とを含み、（Ｃ）強塩基及び（Ｅ）水よりなる群から選択される少なくとも１つを更に含んでいてもよい消毒キットである。
（１２）畜舎消毒用である、（１１）に記載の消毒キット。
(11) According to a seventh aspect of the present invention, there is provided a composition containing (A) a fatty acid salt and (B) at least one cryoprotectant selected from the group consisting of polyhydric alcohols, and (D) a disinfectant. The disinfection kit further comprises (C) a strong base and (E) at least one selected from the group consisting of water.
(12) The disinfection kit according to (11), which is for sterilization of livestock barns.
本発明の消毒組成物、消毒剤を配合するための組成物、及び消毒キットは、冬期の寒冷地（例えば、−３０〜０℃）において、水で希釈した場合であっても凍結することなく、各種病原体に対して消毒殺菌効果を発揮することができ、畜舎消毒用として好適である。
本発明の消毒組成物の製造方法及び消毒方法は、冬期の寒冷地において、水で希釈した場合であっても凍結することなく、各種病原体に対して消毒殺菌することができ、畜舎消毒に好適である。
The disinfecting composition of the present invention, the composition for disinfecting a disinfectant, and the disinfecting kit are not frozen even in a cold region in winter (for example, −30 to 0 ° C.) even when diluted with water. It can exhibit a disinfection and sterilization effect against various pathogens, and is suitable for sterilization of livestock barns.
The manufacturing method and disinfecting method of the disinfecting composition of the present invention can be disinfected and sterilized against various pathogens without freezing even when diluted with water in a cold region in winter, and is suitable for barn disinfection. It is.
以下、本発明の実施態様について詳細に説明するが、本発明は、以下の実施態様に何ら限定されるものではなく、本発明の目的の範囲内において、適宜変更を加えて実施することができる。 Hereinafter, embodiments of the present invention will be described in detail. However, the present invention is not limited to the following embodiments, and can be implemented with appropriate modifications within the scope of the object of the present invention. .
＜消毒組成物＞
第１の態様に係る消毒組成物は、（Ａ）脂肪酸塩及び（Ｂ）多価アルコールを含む凍結防止剤と、（Ｃ）強塩基及び（Ｄ）消毒剤よりなる群から選択される少なくとも１つの消毒成分とを含み、（Ｅ）水を更に含んでいてもよい。
第２の態様に係る消毒組成物は、（Ａ）脂肪酸塩及び（Ｂ１）グリセリンよりなる群から選択される少なくとも１つの凍結防止剤を含み、（Ｅ）水を更に含んでいてもよく、ｐＨ１１以上である。
第３の態様に係る消毒組成物は、（Ａ）脂肪酸塩及び（Ｂ１）グリセリンよりなる群から選択される少なくとも１つの凍結防止剤、並びに（Ｃ）強塩基及び（Ｄ）消毒剤よりなる群から選択される少なくとも１つの消毒成分を含み、（Ｅ）水を更に含んでいてもよい消毒組成物であって、
上記凍結防止剤として上記（Ａ）脂肪酸塩を含み、かつ該（Ａ）脂肪酸塩が酢酸カリウムのとき、消石灰以外の上記（Ｃ）強塩基を含む、消毒組成物である。
<Disinfectant composition>
The disinfecting composition according to the first aspect is at least one selected from the group consisting of (A) a fatty acid salt and (B) a cryoprotectant containing a polyhydric alcohol, (C) a strong base and (D) a disinfectant. And (E) water may further be included.
The disinfecting composition according to the second aspect includes (A) a fatty acid salt and (B1) at least one antifreezing agent selected from the group consisting of glycerin, (E) may further include water, and has a pH of 11 That's it.
The disinfecting composition according to the third aspect includes at least one cryoprotectant selected from the group consisting of (A) a fatty acid salt and (B1) glycerin, and a group consisting of (C) a strong base and (D) a disinfectant. A disinfecting composition comprising at least one disinfecting component selected from (E) and further comprising water,
A disinfecting composition comprising the (A) fatty acid salt as the antifreezing agent, and the (C) strong base other than slaked lime when the (A) fatty acid salt is potassium acetate.
（凍結防止剤）
第１〜３の態様に係る消毒組成物において、（Ａ）脂肪酸塩としては、炭素数１〜５の脂肪酸のアルカリ金属塩又はアルカリ土類金属塩が挙げられ、炭素数１〜３の脂肪酸のアルカリ金属塩又はアルカリ土類金属塩であることが好ましく、炭素数１又は２の脂肪酸のアルカリ金属塩又はアルカリ土類金属塩であることがより好ましい。
（Ａ）脂肪酸塩における脂肪酸としては、ギ酸、酢酸、プロピオン酸、酪酸等が挙げられ、ギ酸又は酢酸であることが好ましい。
アルカリ金属塩又はアルカリ土類金属塩としては、ナトリウム塩、カリウム塩、マグネシウム塩、カルシウム塩、バリウム塩等が挙げられ、ナトリウム塩又はカリウム塩であることが好ましい。
（Ａ）脂肪酸塩の具体例としては、酢酸カリウム、酢酸ナトリウム、酢酸マグネシウム、酢酸カルシウム、酢酸バリウム、ギ酸カリウム、ギ酸ナトリウム、ギ酸マグネシウム、ギ酸カルシウム、ギ酸バリウム、プロピオン酸カリウム、プロピオン酸ナトリウム、プロピオン酸マグネシウム、プロピオン酸カルシウム、プロピオン酸バリウム、酪酸カリウム、酪酸ナトリウム、酪酸マグネシウム、酪酸カルシウム、酪酸バリウム等が挙げられ、酢酸カリウム、酢酸ナトリウム、ギ酸カリウム又はギ酸ナトリウムであることが好ましく、酢酸カリウム又は酢酸ナトリウムであることがより好ましい。
(Antifreezing agent)
In the disinfecting composition according to the first to third aspects, examples of the (A) fatty acid salt include an alkali metal salt or an alkaline earth metal salt of a fatty acid having 1 to 5 carbon atoms. An alkali metal salt or an alkaline earth metal salt is preferable, and an alkali metal salt or an alkaline earth metal salt of a fatty acid having 1 or 2 carbon atoms is more preferable.
(A) As a fatty acid in a fatty acid salt, formic acid, acetic acid, propionic acid, butyric acid, etc. are mentioned, Formic acid or acetic acid is preferable.
Examples of the alkali metal salt or alkaline earth metal salt include sodium salt, potassium salt, magnesium salt, calcium salt, barium salt and the like, and sodium salt or potassium salt is preferable.
Specific examples of (A) fatty acid salts include potassium acetate, sodium acetate, magnesium acetate, calcium acetate, barium acetate, potassium formate, sodium formate, magnesium formate, calcium formate, barium formate, potassium propionate, sodium propionate, propion Examples include magnesium acid, calcium propionate, barium propionate, potassium butyrate, sodium butyrate, magnesium butyrate, calcium butyrate, barium butyrate, etc., preferably potassium acetate, sodium acetate, potassium formate or sodium formate, potassium acetate or More preferred is sodium acetate.
第１の態様に係る消毒組成物において、（Ｂ）多価アルコールとしては、２以上の水酸基（好ましくは、２〜４個の水酸基、より好ましくは２又は３個の水酸基）を有するアルコール化合物である限り特に制限はないが、炭素数２〜４の多価アルコールが挙げられ、炭素数３の多価アルコールが好ましい。
（Ｂ）多価アルコールの具体例としては、（Ｂ１）グリセリン、プロピレングリコール、エチレングリコール、ブチレングリコール等が挙げられ、（Ｂ１）グリセリン又はプロピレングリコールであることが好ましく、（Ｂ１）グリセリンであることがより好ましい。
第１〜３の態様に係る消毒組成物において、凍結防止剤は単独で用いてもよいが、複数種の凍結防止剤を併用してもよい。
In the disinfecting composition according to the first aspect, (B) the polyhydric alcohol is an alcohol compound having two or more hydroxyl groups (preferably 2 to 4 hydroxyl groups, more preferably 2 or 3 hydroxyl groups). Although there is no restriction | limiting in particular as long as it exists, a C2-C4 polyhydric alcohol is mentioned, A C3-C3 polyhydric alcohol is preferable.
Specific examples of (B) polyhydric alcohols include (B1) glycerin, propylene glycol, ethylene glycol, butylene glycol, etc., and (B1) glycerin or propylene glycol is preferred, and (B1) glycerin. Is more preferable.
In the disinfecting composition according to the first to third aspects, the antifreezing agent may be used alone, or a plurality of antifreezing agents may be used in combination.
ここで、水溶液における凍結防止剤と凝固点との関係の例として、酢酸カリウムとグリセリンとの水溶液と凝固点との関係を表１に、グリセリン水溶液と凝固点との関係を表２に示す。
また、図１に水溶液における凍結防止剤濃度と凝固点との関係をグラフにまとめる。
FIG. 1 is a graph summarizing the relationship between the concentration of the cryoprotectant in the aqueous solution and the freezing point.
第１〜３の態様に係る消毒組成物において、消毒組成物の製造性の観点から、上記凍結防止剤の含有量（複数種の凍結防止剤を用いる場合にはその合計含有量）は、（Ｅ）水を含むとき、６５質量％以下であることが好ましい。また、（Ｅ）水で希釈する場合は希釈前の上記凍結防止剤の含有量が、６２質量％以下であることがより好ましく、５８質量％以下であることがさらに好ましく、５５質量％以下であることが特に好ましい。
また、（Ｅ）水で希釈する場合は希釈後の上記凍結防止剤の含有量が、消毒殺菌効果及び凝固点の観点から、６０質量％以下であることがより好ましく、５０質量％以下であることがさらに好ましく、４５質量％以下であることが特に好ましい。
In the disinfecting composition according to the first to third embodiments, from the viewpoint of manufacturability of the disinfecting composition, the content of the antifreezing agent (the total content when using a plurality of antifreezing agents) is ( E) When water is included, it is preferably 65% by mass or less. Further, (E) when diluted with water, the content of the antifreezing agent before dilution is more preferably 62% by mass or less, further preferably 58% by mass or less, and 55% by mass or less. It is particularly preferred.
In addition, when diluted with water (E), the content of the antifreezing agent after dilution is more preferably 60% by mass or less, and 50% by mass or less from the viewpoint of disinfection and sterilization effect and freezing point. Is more preferable, and it is especially preferable that it is 45 mass% or less.
（消毒成分）
第１、第３の態様に係る消毒組成物は、（Ｃ）強塩基及び（Ｄ）消毒剤よりなる群から選択される少なくとも１つの消毒成分を含む。
（Ｃ）強塩基としては、水酸化カリウム、水酸化ナトリウム、消石灰、水酸化バリウム等が挙げられ、水酸化カリウム又は水酸化ナトリウムであることが好ましい。
なお、消石灰は、一般的には消毒剤に分類されることもあるが、本発明においては（Ｃ）強塩基とする。
第１〜３の態様に係る消毒組成物において、（Ｃ）強塩基は単独で用いてもよいが、複数種を併用してもよい。
第１〜３の態様に係る消毒組成物において、（Ｃ）強塩基の含有量（複数種の強塩基を用いる場合にはその合計含有量）としては、消毒殺菌効果を損なわない限り特に制限はないが、使用時に好ましくはｐＨ１１以上、より好ましくはｐＨ１２以上となるように、０．０５〜１５質量％であることが好ましく、０．０５〜１０質量％であることがより好ましく、０．０５〜５質量％であることが更に好ましく、０．０５〜３質量％であることが特に好ましい。
また、第２の態様に係る消毒組成物は、消毒殺菌効果の観点から、ｐＨ１１以上であり、ｐＨ１２以上であることがより好ましい。第２の態様に係る消毒組成物における上記ｐＨの達成方法としては、ｐＨ１１以上になる限り特に制限はないが、例えば、（Ｃ）強塩基を含有させることにより達成してもよい。
(Disinfection component)
The disinfecting composition according to the first and third aspects includes at least one disinfecting component selected from the group consisting of (C) a strong base and (D) a disinfectant.
(C) As a strong base, potassium hydroxide, sodium hydroxide, slaked lime, barium hydroxide, etc. are mentioned, It is preferable that they are potassium hydroxide or sodium hydroxide.
In addition, although slaked lime may generally be classified as a disinfectant, in the present invention, it is (C) a strong base.
In the disinfecting composition according to the first to third embodiments, (C) the strong base may be used alone, or a plurality of types may be used in combination.
In the disinfecting composition according to the first to third aspects, the content of (C) strong base (the total content when using multiple types of strong bases) is not particularly limited as long as the disinfecting and sterilizing effect is not impaired. However, it is preferably 0.05 to 15% by mass, more preferably 0.05 to 10% by mass so that the pH is preferably 11 or more, more preferably 12 or more, at the time of use. More preferably, it is -5 mass%, It is especially preferable that it is 0.05-3 mass%.
Moreover, the disinfecting composition according to the second aspect has a pH of 11 or more, and more preferably a pH of 12 or more, from the viewpoint of the disinfection and sterilization effect. The method for achieving the pH in the disinfecting composition according to the second aspect is not particularly limited as long as the pH is 11 or more. For example, (C) a strong base may be included.
（Ｄ）消毒剤としては、炭酸ナトリウム、クエン酸液、複合次亜塩素酸系消毒剤、塩素系消毒剤、逆性石けん系消毒剤等の任意の消毒剤が挙げられる。
第２の態様に係る消毒組成物は、（Ｄ）消毒剤を含んでいてもよい。
第１〜３の態様に係る消毒組成物において、（Ｄ）消毒剤は単独で用いてもよいが、複数種を併用してもよい。
第１〜３の態様に係る消毒組成物において、（Ｄ）消毒剤の含有量（複数種の消毒剤を用いる場合にはその合計含有量）としては、消毒殺菌効果を損なわない限り特に制限はないが、（Ｅ）水により希釈する場合には、その希釈前の含有量が、０．０１〜２５質量％であることが好ましく、０．０５〜２０質量％であることがより好ましく、０．１〜１８質量％であることが更に好ましく、０．１〜１５質量％であることが特に好ましい。
(D) Examples of the disinfectant include any disinfectant such as sodium carbonate, citric acid solution, complex hypochlorous acid disinfectant, chlorine disinfectant, and reverse soap disinfectant.
The disinfecting composition according to the second aspect may include (D) a disinfectant.
In the disinfecting composition according to the first to third aspects, the (D) disinfectant may be used alone, but a plurality of kinds may be used in combination.
In the disinfecting composition according to the first to third embodiments, the content of (D) disinfectant (the total content when using a plurality of disinfectants) is not particularly limited as long as the disinfecting and disinfecting effect is not impaired. (E) When diluted with water, the content before dilution is preferably 0.01 to 25% by mass, more preferably 0.05 to 20% by mass, More preferably, it is 1-18 mass%, and it is especially preferable that it is 0.1-15 mass%.
第１〜３の態様に係る消毒組成物は、（Ｅ）水を含んでいてもいなくてもよい。
また、第１〜３の態様に係る消毒組成物は、運搬性の観点、使用前の消毒組成物の凝固点を調整する観点及び消毒殺菌効果を調整する観点から、使用時に（Ｅ）水で希釈して用いることも好ましい。希釈倍率として、上記の観点を損なわない限り特に制限はないが、例えば、１．２倍〜１００倍が挙げられ、１．２倍〜５０倍が好ましく、１．２倍〜２５倍がより好ましい。
The disinfecting composition according to the first to third aspects may or may not contain (E) water.
In addition, the disinfecting composition according to the first to third embodiments is diluted with (E) water at the time of use from the viewpoint of transportability, the viewpoint of adjusting the freezing point of the disinfecting composition before use, and the viewpoint of adjusting the disinfection and sterilization effect. It is also preferable to use them. The dilution factor is not particularly limited as long as it does not impair the above viewpoint, and examples include 1.2 to 100 times, preferably 1.2 to 50 times, and more preferably 1.2 to 25 times. .
第１〜３の態様に係る消毒組成物は、環境消毒用（例えば、畜舎消毒用；漁舎消毒用；台所、食堂、食品工場等の食品関連用）、家庭用（食器、食品容器等の消毒用）等として適用し得るが、環境消毒用であることが好ましく、畜舎消毒用であることがより好ましい。
また、第１〜３の態様に係る消毒組成物は、浸漬法、清拭法、洗浄法、擦式法、噴霧法といった各種の消毒法の全てに適用できる。
また、第１〜３の態様に係る消毒組成物は、ウェットティシュ、脱脂綿、不織布等に含浸して除菌シート製品としても使用してもよい。
The disinfecting composition according to the first to third aspects is used for environmental disinfection (for example, for disinfecting livestock houses; for disinfecting fisheries; for food-related products such as kitchens, canteens, food factories, etc.) Although it can be applied as for disinfection), it is preferably for environmental disinfection, and more preferably for barn disinfection.
Moreover, the disinfecting composition according to the first to third embodiments can be applied to all of various disinfecting methods such as a dipping method, a wiping method, a cleaning method, a rubbing method, and a spraying method.
In addition, the disinfecting composition according to the first to third aspects may be used as a sterilized sheet product by impregnating wet tissue, absorbent cotton, nonwoven fabric or the like.
＜消毒剤を配合するための組成物＞
第４の態様に係る（Ｄ）消毒剤を配合するための組成物は、下記組成物１〜４のいずれかである。
組成物１：（Ａ）脂肪酸塩及び（Ｂ）多価アルコールよりなる群から選択される少なくとも１つの凍結防止剤と、（Ｃ）強塩基とを含み、（Ｅ）水を更に含んでいてもよい組成物
組成物２：（Ａ）脂肪酸塩及び（Ｂ）多価アルコールよりなる群から選択される少なくとも１つの凍結防止剤を含み、（Ｅ）水を更に含んでいてもよいｐＨ１１以上の組成物（ただし、上記組成物１を除く。）
組成物３：（Ａ）脂肪酸塩及び（Ｂ）多価アルコールを含む凍結防止剤を含む組成物であって、更に（Ｅ）水を含んでいてもよい組成物（ただし、上記組成物１及び２を除く。）
組成物４：（Ｂ１）グリセリンを含む組成物であって、更に（Ｅ）水を含んでいてもよい組成物（ただし、上記組成物１〜３を除く。）
上記組成物１〜４は、（Ｅ）水を含んでいてもいなくてもよい。
また、運搬性の観点及び使用前の消毒組成物の凝固点を調整する観点から、使用時に（Ｅ）水で希釈して用いることも好ましい。希釈倍率として、上記の観点を損なわない限り特に制限はないが、例えば、１．２倍〜１００倍が挙げられ、１．２倍〜５０倍が好ましく、１．２倍〜２５倍がより好ましい。
<Composition for blending disinfectant>
The composition for mix | blending (D) disinfectant which concerns on a 4th aspect is either of the following compositions 1-4.
Composition 1: (A) a fatty acid salt and (B) at least one cryoprotectant selected from the group consisting of polyhydric alcohols, (C) a strong base, and (E) a water further Good Composition Composition 2: A composition having a pH of 11 or more, which contains (A) a fatty acid salt and (B) at least one antifreezing agent selected from the group consisting of polyhydric alcohols, and (E) may further contain water. Product (excluding Composition 1 above)
Composition 3: (A) a composition containing a fatty acid salt and (B) an antifreezing agent containing a polyhydric alcohol, and (E) a composition which may further contain water (however, the above composition 1 and (Excluding 2)
Composition 4: (B1) A composition containing glycerin, which may further contain (E) water (excluding the above compositions 1 to 3).
The above compositions 1 to 4 may or may not contain (E) water.
Moreover, it is also preferable to dilute and use with (E) water at the time of use from a viewpoint of transportability and the viewpoint of adjusting the freezing point of the disinfecting composition before use. The dilution factor is not particularly limited as long as it does not impair the above viewpoint, and examples include 1.2 to 100 times, preferably 1.2 to 50 times, and more preferably 1.2 to 25 times. .
第４の態様に係る組成物に配合される（Ｄ）消毒剤としては、第１〜３の態様に係る消毒組成物における（Ｄ）消毒剤と同様のものが挙げられ、配合量としても第１〜３の態様に係る消毒組成物における含有量と同様である。 As (D) disinfectant mix | blended with the composition which concerns on a 4th aspect, the thing similar to the (D) disinfectant in the disinfectant composition which concerns on the 1st-3rd aspect is mentioned, and also as the compounding quantity It is the same as content in the disinfecting composition which concerns on the aspect of 1-3.
上記組成物１〜３における（Ａ）脂肪酸塩としては、第１〜３の態様に係る消毒組成物における（Ａ）脂肪酸塩と同様のものが挙げられ、（Ａ）脂肪酸塩の含有量としても第１〜３の態様に係る消毒組成物における含有量と同様である。 As (A) fatty acid salt in the said compositions 1-3, the thing similar to the (A) fatty acid salt in the disinfecting composition which concerns on the 1st-3rd aspect is mentioned, and also as content of (A) fatty acid salt This is the same as the content in the disinfecting composition according to the first to third aspects.
上記組成物１〜３における（Ｂ）多価アルコールとしては、第１の態様に係る消毒組成物における（Ｂ）多価アルコールと同様のものが挙げられ、上記組成物１〜３における（Ｂ）多価アルコール及び上記組成物４における（Ｂ１）グリセリンの含有量としては第１〜３の態様に係る消毒組成物における含有量と同様である。 As (B) polyhydric alcohol in the said compositions 1-3, the thing similar to the (B) polyhydric alcohol in the disinfection composition which concerns on a 1st aspect is mentioned, (B) in the said compositions 1-3 The content of (B1) glycerin in the polyhydric alcohol and the composition 4 is the same as the content in the disinfecting composition according to the first to third aspects.
上記組成物１における（Ｃ）強塩基としては、第１、３の態様に係る消毒組成物における（Ｃ）強塩基と同様のものが挙げられ、上記組成物１における（Ｃ）強塩基の含有量としても第１、３の態様に係る消毒組成物における含有量と同様である。 Examples of the strong base (C) in the composition 1 include the same as the strong base (C) in the disinfecting composition according to the first and third aspects, and the inclusion of the strong base (C) in the composition 1 The amount is the same as the content in the disinfecting composition according to the first and third embodiments.
第４の態様に係る組成物は、任意の（Ｄ）消毒剤を配合することにより消毒組成物として、冬期の寒冷地においても、水で希釈した場合であっても凍結することなく、使用することができる。（Ｄ）消毒剤を配合して得られた上記消毒組成物は浸漬法、清拭法、洗浄法、擦式法、噴霧法といった各種の消毒法の全てに適用し得る。
第４の態様に係る組成物は、環境消毒用、家庭用として適用し得るが、環境消毒用であることが好ましく、畜舎消毒用であることがより好ましい。
The composition according to the fourth aspect is used as a disinfecting composition by blending an arbitrary disinfectant (D) without being frozen even in a cold region in winter or even when diluted with water. be able to. (D) The disinfecting composition obtained by blending a disinfectant can be applied to all of various disinfecting methods such as dipping method, wiping method, cleaning method, rubbing method and spraying method.
The composition according to the fourth aspect can be applied for environmental disinfection and household use, but is preferably for environmental disinfection, and more preferably for barn disinfection.
＜消毒組成物の製造方法＞
第５の態様に係る消毒組成物の製造方法は、第４の態様に係る組成物と（Ｄ）消毒剤とを配合する工程を含む。
第５の態様に係る消毒組成物の製造方法は、（Ｅ）水で希釈する工程を更に含んでいてもいなくてもよいが、運搬性の観点、使用前の消毒組成物の凝固点を調整する観点及び消毒殺菌効果を調整する観点から、（Ｅ）水で希釈する工程を更に含んでいることが好ましい。希釈倍率として、上記の観点を損なわない限り特に制限はないが、例えば、１．２倍〜１００倍が挙げられ、１．２倍〜５０倍が好ましく、１．２倍〜２５倍がより好ましい。
第４の態様に係る組成物を（Ｅ）水で希釈した後に、（Ｄ）消毒剤を配合してもよいし、（Ｄ）消毒剤を（Ｅ）水で希釈した後に、第４の態様に係る組成物を配合してもよいし、第４の態様に係る組成物と（Ｄ）消毒剤とを配合した後に（Ｅ）水で希釈してもよい。
製造された消毒組成物は、環境消毒用、家庭用として適用し得るが、環境消毒用であることが好ましく、畜舎消毒用であることがより好ましい。
<Method for producing disinfecting composition>
The manufacturing method of the disinfecting composition which concerns on a 5th aspect includes the process of mix | blending the composition which concerns on a 4th aspect, and (D) disinfectant.
Although the manufacturing method of the disinfecting composition which concerns on a 5th aspect does not need to further include the process of diluting with (E) water, it adjusts the freezing point of the disinfecting composition before use from a viewpoint of transportability. From the viewpoint of adjusting the viewpoint and the disinfection and sterilization effect, it is preferable to further include a step (E) of diluting with water. The dilution factor is not particularly limited as long as it does not impair the above viewpoint, and examples include 1.2 to 100 times, preferably 1.2 to 50 times, and more preferably 1.2 to 25 times. .
After the composition according to the fourth aspect is diluted with (E) water, (D) a disinfectant may be added, or after the (D) disinfectant is diluted with (E) water, the fourth aspect. You may mix | blend the composition which concerns on this, and you may dilute with water after mix | blending the composition which concerns on a 4th aspect, and (D) disinfectant.
The manufactured disinfecting composition can be applied for environmental disinfection and household use, but is preferably for environmental disinfection, and more preferably for barn disinfection.
＜消毒方法＞
第６の態様に係る消毒方法は、第４の態様に係る組成物に（Ｄ）消毒剤を配合する工程を含み、上記工程により消毒組成物が調製される。
また、第６の態様に係る消毒方法は、通常、上記工程により調製された消毒組成物を消毒対象物（畜舎、漁舎、台所、食堂、食品工場、食器、食品容器等）に適用する工程を更に含む。
適用する方法としては浸漬法、清拭法、洗浄法、擦式法、噴霧法といった各種の消毒法の全てが適用し得る。
また、第６の態様に係る消毒方法は、（Ｅ）水で希釈する工程を更に含んでいてもいなくてもよいが、運搬性の観点、使用前の組成物の凝固点を調整する観点及び消毒殺菌効果を調整する観点から、（Ｅ）水で希釈する工程を更に含んでいることが好ましい。希釈倍率として、上記の観点を損なわない限り特に制限はないが、例えば、１．２倍〜１００倍が挙げられ、１．２倍〜５０倍が好ましく、１．２倍〜２５倍がより好ましい。
<Disinfection method>
The disinfecting method according to the sixth aspect includes a step (D) of adding a disinfectant to the composition according to the fourth aspect, and the disinfecting composition is prepared by the above-described steps.
Moreover, the disinfection method which concerns on a 6th aspect is the process of applying the disinfecting composition normally prepared by the said process to disinfecting objects (a livestock barn, a fishhouse, a kitchen, a canteen, a food factory, tableware, a food container etc.). Is further included.
As a method to be applied, all of various disinfection methods such as a dipping method, a wiping method, a cleaning method, a rubbing method, and a spray method can be applied.
In addition, the disinfection method according to the sixth aspect may or may not further include the step (E) of diluting with water, but the viewpoint of transportability, the viewpoint of adjusting the freezing point of the composition before use, and the disinfection From the viewpoint of adjusting the bactericidal effect, it is preferable to further include (E) a step of diluting with water. The dilution factor is not particularly limited as long as it does not impair the above viewpoint, and examples include 1.2 to 100 times, preferably 1.2 to 50 times, and more preferably 1.2 to 25 times. .
＜消毒キット＞
第７の態様に係る消毒キットは、（Ａ）脂肪酸塩及び（Ｂ）多価アルコールよりなる群から選択される少なくとも１つの凍結防止剤を含む組成物と、（Ｄ）消毒剤とを含み、（Ｃ）強塩基及び（Ｅ）水よりなる群から選択される少なくとも１つを更に含んでいてもよい。
第７の態様に係る消毒キットの実施態様は、（Ａ）脂肪酸塩及び（Ｂ）多価アルコールよりなる群から選択される少なくとも１つの凍結防止剤を含む組成物と、（Ｄ）消毒剤とが別々の任意の容器に含有された消毒キットであって、使用時に、上記凍結防止剤を含む組成物と上記（Ｄ）消毒剤とを配合して用いる消毒キット等が挙げられる。運搬性の観点、使用前の消毒キットの凝固点を調整する観点及び消毒殺菌効果を調整する観点から、使用時に、更に（Ｅ）水で希釈して用いる消毒キットであることが好ましい。希釈倍率として、上記の観点を損なわない限り特に制限はないが、例えば、１．２倍〜１００倍が挙げられ、１．２倍〜５０倍が好ましく、１．２倍〜２５倍がより好ましい。
<Disinfection kit>
The disinfection kit according to the seventh aspect includes a composition containing (A) a fatty acid salt and (B) at least one cryoprotectant selected from the group consisting of polyhydric alcohols, and (D) a disinfectant. (C) At least one selected from the group consisting of a strong base and (E) water may further be included.
An embodiment of the disinfection kit according to the seventh aspect includes a composition comprising (A) a fatty acid salt and (B) at least one cryoprotectant selected from the group consisting of polyhydric alcohols, and (D) a disinfectant. Is a disinfection kit contained in any arbitrary container, and includes a disinfection kit used by combining the composition containing the antifreezing agent and the (D) disinfectant at the time of use. From the viewpoint of transportability, the viewpoint of adjusting the freezing point of the disinfection kit before use, and the viewpoint of adjusting the disinfection and sterilization effect, (E) a disinfection kit that is further diluted with water during use is preferable. The dilution factor is not particularly limited as long as it does not impair the above viewpoint, and examples include 1.2 to 100 times, preferably 1.2 to 50 times, and more preferably 1.2 to 25 times. .
第７の態様に係る消毒キットにおける（Ａ）脂肪酸塩、（Ｂ）多価アルコール、（Ｃ）強塩基、（Ｄ）消毒剤としては、第１〜３の態様に係る消毒組成物における（Ａ）脂肪酸塩、（Ｂ）多価アルコール、（Ｃ）強塩基、（Ｄ）消毒剤と同様のものが挙げられ、第７の態様に係る消毒キットにおける（Ａ）脂肪酸塩、（Ｂ）多価アルコール、（Ｃ）強塩基、（Ｄ）消毒剤の含有量としても第１〜３の態様に係る消毒組成物における含有量と同様である。
第７の態様に係る消毒キットは、環境消毒用、家庭用として適用し得るが、環境消毒用であることが好ましく、畜舎消毒用であることがより好ましい。
The (A) fatty acid salt, (B) polyhydric alcohol, (C) strong base, and (D) disinfectant in the disinfecting kit according to the seventh aspect include (A) in the disinfecting composition according to the first to third aspects (A ) Fatty acid salt, (B) polyhydric alcohol, (C) strong base, (D) the same as the disinfectant, (A) fatty acid salt, (B) polyvalent in the disinfection kit according to the seventh aspect The contents of alcohol, (C) strong base, and (D) disinfectant are the same as those in the disinfecting composition according to the first to third embodiments.
The disinfection kit according to the seventh aspect can be applied for environmental disinfection and household use, but is preferably for environmental disinfection, and more preferably for barn disinfection.
以下、実施例を示して本発明を更に具体的に説明するが、本発明の範囲は、これらの実施例に限定されるものではない。 EXAMPLES Hereinafter, although an Example is shown and this invention is demonstrated further more concretely, the scope of the present invention is not limited to these Examples.
＜試験１（凍結状況の検証）＞
Ａ１）各種組成の水溶液（比較例１〜６及び実施例１〜１３の消毒組成物）を調製した。
実施例１〜１３については、各種（Ｄ）消毒剤溶液を調製後、酢酸カリウムとグリセリンと水酸化カリウムとの水溶液で希釈し、表３に示した成分比率（質量％）とした。
Ａ２）上記Ａ１）をシャーレに２ｍＬ入れた。
Ａ３）上記Ａ２）のシャーレを−２０℃の環境の冷凍庫に入れ、冷却した。
Ａ４）冷却開始から２４時間後に冷凍庫から上記Ａ３）のシャーレを取り出した。
Ａ５）水溶液の凍結状況の有無を目視で確認した。
（判定方法）
凍結状況は、凍結して固体若しくはシャーベット状態を凍結有り（×）と判定し、液体状を凍結無し（〇）と判定した。
各種組成の凍結環境下（−２０℃）における凍結状況の検証結果を下記表３に示す。
A1) Aqueous solutions having various compositions (disinfecting compositions of Comparative Examples 1 to 6 and Examples 1 to 13) were prepared.
About Examples 1-13, after preparing various (D) disinfectant solution, it diluted with the aqueous solution of potassium acetate, glycerol, and potassium hydroxide, and was set as the component ratio (mass%) shown in Table 3.
A2) 2 mL of the above A1) was placed in a petri dish.
A3) The petri dish of A2) was placed in a freezer having an environment of −20 ° C. and cooled.
A4) The petri dish of A3) was taken out of the freezer 24 hours after the start of cooling.
A5) The presence or absence of the frozen state of the aqueous solution was visually confirmed.
(Judgment method)
As for the freezing state, the solid or sherbet state was determined to be frozen (×), and the liquid state was determined to be freezing (◯).
Table 3 below shows the results of verification of the freezing conditions under freezing environments (−20 ° C.) of various compositions.
上記表３に示した結果から明らかなように、凍結防止剤を含有させない比較例１〜６はいずれも凍結環境下（−２０℃）において凍結することがわかる。
一方、凍結防止剤を含有する実施例１〜１３はいずれも凍結環境下（−２０℃）において凍結しないことがわかる。
As is clear from the results shown in Table 3 above, it can be seen that Comparative Examples 1 to 6 containing no antifreezing agent are all frozen in a freezing environment (−20 ° C.).
On the other hand, it can be seen that Examples 1 to 13 containing an antifreezing agent do not freeze in a freezing environment (−20 ° C.).
＜試験２（サルモネラ菌への消毒殺菌効果の検証）＞
Ｂ１）試験１の上記Ａ１）をシャーレに２ｍＬ入れた。
Ｂ２）上記Ｂ１）のシャーレを−２０℃の環境の冷凍庫に入れ、冷却した。
Ｂ３）上記Ｂ２）のシャーレにマクファーランド４に調整した菌液を加えた。
Ｂ４）−２０℃の環境下で５分間反応させた。
Ｂ５）生理食塩水で速やかに希釈した。
Ｂ６）冷凍庫から取り出した。
Ｂ７）生菌数を測定した。
ここで、マクファーランド４は菌液の生菌数を濁度から推定する方法であり、４はマクファーランド標準濁度の番号である。
<Test 2 (Verification of disinfection and bactericidal effect on Salmonella)>
B1) 2 mL of the above A1) of Test 1 was placed in a petri dish.
B2) The petri dish of B1) was placed in a freezer having an environment of −20 ° C. and cooled.
B3) The bacterial solution adjusted to McFarland 4 was added to the petri dish of B2).
B4) The mixture was reacted for 5 minutes in an environment of -20 ° C.
B5) Diluted quickly with physiological saline.
B6) Removed from freezer.
B7) Viable count was measured.
Here, McFarland 4 is a method for estimating the viable cell count of the bacterial solution from the turbidity, and 4 is a McFarland standard turbidity number.
（判定方法）
常温（２０℃）の水道水中の生菌数と比較し、消毒殺菌効果を評価した。菌数が１／１０以下に減少した場合を「◎」、菌数の減少が１／１０未満の場合を「○」、水道水の効果と同等の場合を「×」とした。
各種組成の凍結環境下（−２０℃）におけるサルモネラ菌（Ｓａｌｍｏｎｅｌｌａ Ｔｙｐｈｉｍｕｒｉｕｍ：ＳＴ）への消毒殺菌効果の検証結果を下記表４に示す。
Compared with the number of viable bacteria in normal temperature (20 ° C.) tap water, the disinfection and sterilization effect was evaluated. The case where the number of bacteria was reduced to 1/10 or less was “◎”, the case where the decrease in the number of bacteria was less than 1/10 was “◯”, and the case equivalent to the effect of tap water was “×”.
Table 4 below shows the results of verification of the disinfection and sterilization effect on Salmonella typhimurium (ST) under freezing environments (−20 ° C.) having various compositions.
上記表４に示した結果から明らかなように、比較例１〜６については、試料が凍結したため検証できなかった。
一方、実施例１〜１３はいずれも凍結環境下（−２０℃）においてＳＴへの消毒殺菌効果がみられることがわかる。実施例１、２、４〜８、１０〜１３は、特に、ＳＴへの消毒殺菌効果に優れることがわかる。
As is clear from the results shown in Table 4 above, Comparative Examples 1 to 6 could not be verified because the samples were frozen.
On the other hand, it can be seen that Examples 1 to 13 have a disinfecting and sterilizing effect on ST in a freezing environment (−20 ° C.). It turns out that Example 1, 2, 4-8, 10-13 is excellent in the disinfection sterilization effect to ST especially.
＜試験３（各病原体への消毒効果の検証）＞
Ｃ２）試験１の上記Ａ１）をシャーレに２ｍＬ入れた。
Ｃ３）上記Ｃ２）のシャーレを−２０℃の環境の冷凍庫に入れ、冷却した。
Ｃ４）上記Ｃ３）のシャーレに各種病原体液（ＩＢＲＶ／ＢＣＶ／ＳＩＶ／ＢＶＤＶ／ＡｄＶ−７）を加えた。
ここで、ＩＢＲＶは牛伝染性鼻気管炎ウイルスであり、ＢＣＶは牛コロナウイルスであり、ＳＩＶは豚インフルエンザウイルスであり、ＢＶＤＶは牛ウイルス性下痢ウイルスであり、ＡｄＶ−７は牛アデノウイルス７型である。
Ｃ５）−２０℃の環境下で５分間反応させた。
Ｃ６）９６穴マイクロプレート及び各種病原体に対する培養細胞を用いて、細胞変性効果（Ｃｙｔｏｐａｔｈｉｃ Ｅｆｆｅｃｔ：ＣＰＥ）を指標に５０％感染終末点（ＴＣＩＤ５０）を測定した。
ここで、ＩＢＲＶに対してはＭＤＢＫ細胞（牛腎由来の細胞株）、ＢＣＶに対してはＨＲＴ１８Ｇ細胞（ヒト直腸由来の細胞株）、ＳＩＶに対してはＭＤＣＫ細胞（イヌ腎由来の細胞株）、ＢＶＤＶに対してはＭＤＢＫ−ＳＹ細胞（牛腎由来の細胞株）、ＡｄＶ−７に対しては牛胎子血管内皮細胞を用いた。
Ｃ７）上記Ｃ６）から病原体の力価を算出した。
（判定方法）
常温の水道水中の病原体の力価と比較し病原体の力価により消毒殺菌効果を評価した。病原体の力価が１／１０以下に低下した場合を「◎」、病原体の力価の低下が１／１０未満の場合を「○」、水道水の効果と同等の場合を「×」とした。
各種組成の凍結環境下（−２０℃）における各種病原体（ＩＢＲＶ／ＢＣＶ／ＳＩＶ／ＢＶＤＶ／ＡｄＶ−７）への消毒殺菌効果の検証結果を下記表５に示す。
C2) 2 mL of the above A1) of Test 1 was placed in a petri dish.
C3) The petri dish of C2) was put in a freezer having an environment of −20 ° C. and cooled.
C4) Various pathogen fluids (IBRV / BCV / SIV / BVDV / AdV-7) were added to the petri dish of C3).
Here, IBRV is bovine infectious rhinotracheitis virus, BCV is bovine coronavirus, SIV is swine influenza virus, BVDV is bovine viral diarrhea virus, AdV-7 is bovine adenovirus type 7 It is.
C5) The reaction was performed for 5 minutes in an environment of -20 ° C.
C6) Using a 96-well microplate and cultured cells against various pathogens, 50% infection end point (TCID 50 ) was measured using cytopathic effect (CPE) as an index.
Here, MDBK cells (cell line derived from bovine kidney) for IBRV, HRT18G cells (cell line derived from human rectum) for BCV, MDCK cells (cell line derived from canine kidney) for SIV MDBK-SY cells (bovine kidney-derived cell line) were used for BVDV, and bovine fetal vascular endothelial cells were used for AdV-7.
C7) The titer of the pathogen was calculated from the above C6).
(Judgment method)
The disinfection and sterilization effect was evaluated based on the titer of the pathogen compared with the titer of the pathogen in normal temperature tap water. “◎” indicates that the titer of the pathogen has decreased to 1/10 or less, “○” indicates that the decrease in the titer of the pathogen is less than 1/10, and “x” indicates a case equivalent to the effect of tap water. .
The verification results of the disinfection and sterilization effect on various pathogens (IBRV / BCV / SIV / BVDV / AdV-7) under freezing environment (−20 ° C.) with various compositions are shown in Table 5 below.
上記表５に示した結果から明らかなように、比較例１〜６については、試料が凍結したため検証できなかった。
一方、実施例１〜１３はいずれも凍結環境下（−２０℃）において各種病原体（ＩＢＲＶ／ＢＣＶ／ＳＩＶ／ＢＶＤＶ／ＡｄＶ−７）の少なくともいずれかへの消毒殺菌効果がみられることがわかる。複合次亜塩素酸系又は塩素系消毒剤を使用した実施例４、５、１０、１１は、特に、いずれの病原体（ＩＢＲＶ／ＢＣＶ／ＳＩＶ／ＢＶＤＶ／ＡｄＶ−７）に対しても消毒殺菌効果に優れることがわかる。
As is clear from the results shown in Table 5, Comparative Examples 1 to 6 could not be verified because the samples were frozen.
On the other hand, it can be seen that Examples 1 to 13 all show a disinfection and sterilization effect on at least one of various pathogens (IBRV / BCV / SIV / BVDV / AdV-7) in a freezing environment (−20 ° C.). Examples 4, 5, 10, and 11 using a complex hypochlorous acid-based or chlorine-based disinfectant are particularly effective for disinfecting and disinfecting any pathogen (IBRV / BCV / SIV / BVDV / AdV-7). It turns out that it is excellent.
Claims (10)
（Ａ）脂肪酸塩及び（Ｂ）多価アルコールを含む凍結防止剤、並びに（Ｃ）水酸化カリウム及び水酸化ナトリウムよりなる群から選択される少なくとも１つの強塩基０．１質量％超１５質量％以下（ただし、２質量％を除く。）を含む組成物であって、（Ｅ）水を更に含んでいてもよい組成物。 (D) a composition having a pH of 12 or more for blending a disinfectant,
(A) Antifreezing agent containing fatty acid salt and (B) polyhydric alcohol, and (C) at least one strong base selected from the group consisting of potassium hydroxide and sodium hydroxide, more than 0.1% by mass and more than 15% by mass A composition containing the following (excluding 2% by mass), wherein (E) the composition may further contain water.
The disinfection kit according to claim 9, which is used for sterilization of barns.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016184301A JP6144397B1 (en) | 2016-09-21 | 2016-09-21 | Disinfecting composition, composition for incorporating disinfectant, disinfecting composition manufacturing method, disinfecting method, and disinfecting kit |
| KR1020170120491A KR20180032188A (en) | 2016-09-21 | 2017-09-19 | Disinfectant composition, composition for blending disinfectant, method for manufacturing disinfectant composition, method of disinfection and disinfection kit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016184301A JP6144397B1 (en) | 2016-09-21 | 2016-09-21 | Disinfecting composition, composition for incorporating disinfectant, disinfecting composition manufacturing method, disinfecting method, and disinfecting kit |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP6144397B1 true JP6144397B1 (en) | 2017-06-07 |
| JP2018048089A JP2018048089A (en) | 2018-03-29 |
Family
ID=59012164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016184301A Active JP6144397B1 (en) | 2016-09-21 | 2016-09-21 | Disinfecting composition, composition for incorporating disinfectant, disinfecting composition manufacturing method, disinfecting method, and disinfecting kit |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP6144397B1 (en) |
| KR (1) | KR20180032188A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112955009A (en) * | 2018-10-31 | 2021-06-11 | 富士胶片株式会社 | Composition, sprayer and wiping cloth |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102607818B1 (en) * | 2021-05-07 | 2023-11-29 | 건국대학교 산학협력단 | Antifreezing disinfectant composition and preparation method thereof |
| WO2023072553A1 (en) * | 2021-10-29 | 2023-05-04 | Syngenta Crop Protection Ag | Organic salts for agrochemical formulations |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0948961A (en) * | 1995-08-04 | 1997-02-18 | M & Ii Kk | Deicer |
| JP2002524398A (en) * | 1998-09-03 | 2002-08-06 | アルサイド コーポレーション | Stabilized two-part disinfection systems and related compositions and methods |
| JP2002338401A (en) * | 2001-03-29 | 2002-11-27 | Nel Biotech Co Ltd | Method for producing stabilized liquid silicate and carbonate disinfecting agent |
| JP2005023167A (en) * | 2003-06-30 | 2005-01-27 | Aomori Prefecture | Liquid antifreezing agent and manufacturing process of liquid antifreezing agent |
| JP2011173882A (en) * | 2011-02-25 | 2011-09-08 | Tagen Sekkai Kogyo Kk | Disinfectant for barn |
| WO2012121077A1 (en) * | 2011-03-04 | 2012-09-13 | サンライズ産業株式会社 | Prevention method and preventive solidified substance, method for applying preventive solidified substance, base material and material used in application of preventive solidified substance, and method for producing preventive solidified substance |
| US20140106008A1 (en) * | 2011-06-24 | 2014-04-17 | Bio-Energy Ingredients Limited | Glycerol compositions and solutions |
| JP2016023492A (en) * | 2014-07-23 | 2016-02-08 | 北海道日油株式会社 | Liquid antifreezing agent feeding device |
| JP5920753B1 (en) * | 2015-11-05 | 2016-05-18 | 北海道日油株式会社 | Liquid antifreeze |
-
2016
- 2016-09-21 JP JP2016184301A patent/JP6144397B1/en active Active
-
2017
- 2017-09-19 KR KR1020170120491A patent/KR20180032188A/en not_active Application Discontinuation
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0948961A (en) * | 1995-08-04 | 1997-02-18 | M & Ii Kk | Deicer |
| JP2002524398A (en) * | 1998-09-03 | 2002-08-06 | アルサイド コーポレーション | Stabilized two-part disinfection systems and related compositions and methods |
| JP2002338401A (en) * | 2001-03-29 | 2002-11-27 | Nel Biotech Co Ltd | Method for producing stabilized liquid silicate and carbonate disinfecting agent |
| JP2005023167A (en) * | 2003-06-30 | 2005-01-27 | Aomori Prefecture | Liquid antifreezing agent and manufacturing process of liquid antifreezing agent |
| JP2011173882A (en) * | 2011-02-25 | 2011-09-08 | Tagen Sekkai Kogyo Kk | Disinfectant for barn |
| WO2012121077A1 (en) * | 2011-03-04 | 2012-09-13 | サンライズ産業株式会社 | Prevention method and preventive solidified substance, method for applying preventive solidified substance, base material and material used in application of preventive solidified substance, and method for producing preventive solidified substance |
| US20140106008A1 (en) * | 2011-06-24 | 2014-04-17 | Bio-Energy Ingredients Limited | Glycerol compositions and solutions |
| JP2016023492A (en) * | 2014-07-23 | 2016-02-08 | 北海道日油株式会社 | Liquid antifreezing agent feeding device |
| JP5920753B1 (en) * | 2015-11-05 | 2016-05-18 | 北海道日油株式会社 | Liquid antifreeze |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112955009A (en) * | 2018-10-31 | 2021-06-11 | 富士胶片株式会社 | Composition, sprayer and wiping cloth |
| CN112955009B (en) * | 2018-10-31 | 2022-10-25 | 富士胶片株式会社 | Composition, sprayer and wiping cloth |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018048089A (en) | 2018-03-29 |
| KR20180032188A (en) | 2018-03-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1406494B1 (en) | Bactericidal composition comprising polylysin and plant natural oils | |
| ES2749962T3 (en) | Ready-to-use, reduced corrosion, storage-stable peroxycarboxylic acid antimicrobial compositions | |
| CN107001989B (en) | Natural source surface cleaning agent and disinfectant | |
| JP2009173641A (en) | Bactericidal disinfectant composition, bactericidal disinfectant material comprising the same, and bactericidal disinfection method using the same composition or the same material | |
| JP6920298B2 (en) | Amide-containing composition | |
| JP6144397B1 (en) | Disinfecting composition, composition for incorporating disinfectant, disinfecting composition manufacturing method, disinfecting method, and disinfecting kit | |
| AU2011247315B2 (en) | Deformable mass for disinfecting surfaces, based on cross-linked hydropropylated polygalactomannan | |
| JP2007512356A (en) | Antibacterial composition containing aromatic carboxylic acid and aqueous solvent | |
| WO2009093476A1 (en) | Antibacterial cleaner composition for toilet seat, antibacterial cleaning material comprising the same, and antibacterial cleaning method using the composition or the material | |
| JP6454805B1 (en) | Alcohol preparation and disinfection method using the same | |
| JP2018537479A (en) | Composition comprising ester and / or acid | |
| ES2711508T3 (en) | Additives of disinfectant rinse based on peroxycarboxylic acid for use in dishwashing | |
| US7481973B2 (en) | Composition and process for chemical and thermal disinfection | |
| JP2008081739A (en) | Aromatic detergent for toilet | |
| JP6688929B1 (en) | Disinfectant composition, sanitary material, food cleaning agent, and food preservative | |
| JP2019052107A (en) | Bactericidal and virus inactivation agent and bactericidal and virus inactivation method | |
| BR112021006553A2 (en) | antimicrobial compositions containing c3-c5 n-alkyl-gamma-butyrolactam and uses thereof | |
| WO2014115860A1 (en) | Virucidal agent | |
| JP6409201B2 (en) | Disinfectant composition | |
| JP2006508139A (en) | Compositions and methods for disinfecting breasts during winter environments | |
| KR20150030525A (en) | Composition for disinfecting foot-and-mouth disease virus | |
| JP2022058054A (en) | Skin disinfectant composition | |
| Thormar et al. | Antimicrobial lipids as disinfectants, antiseptics and sanitizers | |
| JP2005247779A (en) | Tea tree-including ethanol composition | |
| CN104523454A (en) | Skin disinfection wet wipe |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170331 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20170411 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20170510 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6144397 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313111 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |