KR20170141870A - Mouth and nose cleaning liquid comprising oxygen - Google Patents

Mouth and nose cleaning liquid comprising oxygen Download PDF

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Publication number
KR20170141870A
KR20170141870A KR1020160074828A KR20160074828A KR20170141870A KR 20170141870 A KR20170141870 A KR 20170141870A KR 1020160074828 A KR1020160074828 A KR 1020160074828A KR 20160074828 A KR20160074828 A KR 20160074828A KR 20170141870 A KR20170141870 A KR 20170141870A
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water
mucous membrane
oxygen
present
nasal
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KR1020160074828A
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Korean (ko)
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김대호
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김대호
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    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/02Inorganic compounds
    • C11D7/04Water-soluble compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22Peroxides; Oxygen; Ozone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/02Inorganic compounds
    • C11D7/04Water-soluble compounds
    • C11D7/10Salts

Abstract

The present invention relates to a nasal cavity and oral cavity cleansing solution. More specifically, the present invention relates to a nasal cavity and oral cavity cleansing solution capable of cleansing a mucous membrane of a nasal cavity and an oral cavity. According to the present invention, a cleansing solution for cleansing a nasal cavity and/or an oral cavity contains high concentration oxygen of 80 ppm or more as an effective ingredient. The present invention can activate the functions of a mucous membrane and cilia formed on the mucous membrane by cleansing a nasal cavity and an oral cavity with a mucous membrane cleansing solution consisting of high concentration oxygen water to supply oxygen directly to the mucous membrane. In addition, since the mucous membrane cleansing solution, according to the present invention, is made of the same ingredient as water, in spite of being used repeatedly for long hours, a side effect caused by artificial chemicals can be minimized. Moreover, the mucous membrane cleansing solution can effectively alleviate symptoms such as rhinitis, a sore throat, or the like, because high concentration oxygen dissolved in water treats various inflammations or the like in the mucous membrane.

Description

산소를 포함하는 비강 및 구강 세척액{MOUTH AND NOSE CLEANING LIQUID COMPRISING OXYGEN}BACKGROUND OF THE INVENTION 1. Field of the Invention [0001] The present invention relates to a nasal and oral cleaning solution containing oxygen,

본 발명은 비강 및 구강 세척제에 관한 것으로서, 보다 상세하게는 구강 및 비강의 점막을 세척할 수 있는 비강 및 구강 세척액에 관한 것이다. The present invention relates to nasal and oral cleansers, and more particularly, to nasal and oral cleansing solutions capable of cleansing mucous membranes of the oral and nasal cavities.

최근 미세먼지의 문제가 환경적으로 심각해지면서, 마스크 등의 개인 위생 제품이 판매되고 있으며, 구강이나 비강을 청결케 할 수 있는 세척제에 대한 관심이 높아지고 있다. Recently, as the problem of fine dust becomes more environmentally serious, personal hygiene products such as masks are being sold, and there is a growing interest in cleaning agents that can clean mouth and nasal passages.

종래 구강 세척제는 탄산이나 특수 기능성 물질을 물에 용해시켜 사용하는 것이지만, 탄산의 경우 치아침식증은 유발할 수 있으며, 특수 기능성 물질은 다수의 화학물질들을 포함하고 있어 그 효과에도 불구하고 제품이 친환경적이지 않다는 문제가 있다.Conventional oral cleansers are used by dissolving carbonic acid or a special functional substance in water. However, carbonic acid may cause dental erosion, and a special functional substance includes many chemical substances. Therefore, the product is environmentally friendly There is a problem that it is not.

대한민국 특허 공개 10-2000-0036407호에서는 탄산을 포함하는 구강 세척제를 개시한다. 구강 세척제에 탄산을 첨가 하므로서 구강 세척시 탄산에 의한 발포 효과로 인해 세척제의 용해 작용을 도와 틈새의 깊숙한 곳까지 침투하여 보다 나은 세척 효과를 기대할 수 있으며 또한 탄산의 톡 톡 튀는 느낌이 사용감을 좋게하여 구강세척을 깨끗하고 기분을 상쾌하게 하는 효과가 있다. Korean Patent Laid-Open Publication No. 10-2000-0036407 discloses a mouthwash containing carbonic acid. By adding carbonic acid to the mouthwash, it helps the dissolving action of the cleaning agent due to the foaming effect by the carbonic acid during the oral cleaning. It can penetrate deep into the gap and can expect a better cleaning effect. Also, It has the effect of refreshing mouth clean and refreshing feeling.

대한민국 특허 공개 10-2005-0093558호에서는 한국산 겨우살이 추출물을 유효성분으로 함유하는 점막면역 증진용 세척제 조성물을 공개한다. 이 세척제 조성물은 한국산 겨우살이를 수세하여 자연 탈수시킨 후 세절하고 중량에 대해 5배량의 증류수를 넣어 2시간 동안 비등시켜 물 추출한 후 원심분리에 의해 얻어진 상등액을 여과하여 동결건조시킴으로써 얻은 무균상태의 한국산 겨우살이 물 추출물을 포함하는 것을 특징으로 한다. 이러한 세척용 조성물을 사용하면, 코, 기도, 기관지 및 폐와 같은 호흡기관과 소장과 같은 소화기관들의 표면 상피세포들을 할성화시켜 면역기능을 증진시킴으로써 공기 중이나 식품으로부터의 감염을 예방할 수 있음이 밝혀졌다.Korean Patent Publication No. 10-2005-0093558 discloses a detergent composition for enhancing mucosal immunity containing Korean mistletoe extract as an active ingredient. This detergent composition was prepared by dissolving the Korean mistletoe, dehydrating it naturally, finely dividing it by 5 times the weight of distilled water, boiling it for 2 hours, extracting the water, filtering the supernatant obtained by centrifugation and lyophilizing the aseptic Korean mistletoe And a water extract. Using such a cleaning composition, it has been found that by infecting surface epithelial cells of respiratory organs such as nose, airway, bronchus and lung and digestive organs such as small intestine, it is possible to prevent infection from airborne and food by enhancing immune function lost.

이에 따라, 새로운 구강 또는 비강 세척제에 대한 요구가 계속되고 있다. Accordingly, there is a continuing need for new oral or nasal cleansers.

본 발명에서 해결하고자 하는 과제는 구강 및 비강 내부에 산소를 직접 공급할 수 있는 새로운 구강 및/또는 비강 세척제를 제공하는 것이다. A problem to be solved by the present invention is to provide a new oral and / or nasal cleaning agent capable of directly supplying oxygen into the oral cavity and nasal cavity.

본 발명에서 해결하고자 하는 과제는 치아 부식과 같은 부작용이 없으며, 소독 효과가 있는 새로운 구강 세척제를 제공하는 것이다. A problem to be solved by the present invention is to provide a new oral cleanser having no side effects such as tooth corrosion and having a disinfecting effect.

상기와 같은 과제를 해결하기 위해서, 본 발명에 따른 비강 점막 세척액은 80 ppm 이상의 고농도 산소를 유효성분으로 포함하는 것을 특징으로 한다. In order to solve the above-mentioned problems, the nasal mucosal washing solution according to the present invention is characterized by containing high concentration oxygen of 80 ppm or more as an active ingredient.

본 발명에 있어서, 상기 구강 및/또는 비강 세척액에는 바람직하게는 100 ppm 이상, 보다 바람직하게는 120 ppm 이상의 산소가 용존되어 있을 수 있다. 일 예로 80~250 ppm의 산소가 녹아있을 수 있다. In the present invention, the oral and / or nasal washings preferably contain at least 100 ppm oxygen, more preferably at least 120 ppm oxygen dissolved therein. For example, 80 to 250 ppm of oxygen may be dissolved.

이론적으로 한정된 것은 아니지만, 고농도의 산소수를 이용하여 비강 또는 구강을 세척하게 되면, 고농도의 산소가 점막 피부에 직접 공급되어, 점막에 있는 섬모의 기능을 활성화시키게 된다. 또한, 산소 수에 포함된 고농도의 산소가 일부 용출되면서 점막에 부착된 미세먼지와 같은 각종 오염물들을 분해하고, 세균들을 살균하여 비강 또는 구강의 건강을 유지시킬 수 있게 된다. Although it is not theoretically possible to limit the use of a high concentration of oxygenated water to clean the nasal cavity or mouth, a high concentration of oxygen is directly supplied to the mucosal skin to activate the function of the mucous cilia. In addition, as the high concentration of oxygen contained in the oxygen water is partially eluted, various pollutants such as fine dust adhering to the mucous membrane can be decomposed and bacteria can be sterilized to maintain the health of the nasal cavity or oral cavity.

본 발명에 있어서, 상기 산소의 농도가 적어지면 점막에 대한 산소 공급효과가 적어지며, 세척 및 살균 효과가 적어진다. 상기 산소의 농도가 지나치게 높아지면 농도에 대한 비례적인 효과가 없이 제조 비용이 많이 들고, 유통 등이 어려워질 수 있다. In the present invention, when the concentration of oxygen is decreased, the oxygen supply effect to the mucous membrane is reduced, and the washing and sterilizing effect is reduced. If the concentration of oxygen is excessively high, there is no proportional effect on the concentration, and the manufacturing cost is high and the distribution can be difficult.

본 발명에 있어서, 상기 점막 세척액에는 산소가 용해된 상태로 포함된다. In the present invention, oxygen is dissolved in the mucosal washing liquid.

본 발명에 있어서, 상기 산소를 포함하는 액체는 물을 주성분으로 하는 액체일 수 있으며, 바람직하게는 물이다. In the present invention, the oxygen-containing liquid may be a liquid containing water as a main component, preferably water.

본 발명에 있어서, 상기 점막 세척액에는 체액과 유사한 염도를 가질 수 있도록 소금을 포함할 수 있으며, 보다 효과적으로 세척과 살균 작용을 일으킬 수 있도록 죽염을 더 포함할 수 있다. In the present invention, the mucosal washing solution may include salt to have a saltiness similar to body fluids, and may further include bamboo salt so as to more effectively cause washing and sterilizing action.

본 발명에 있어서, 상기 점막 세척액에는 개봉 후에는 고농도로 용존된 산소가 용출되므로, 개봉 후 1~2일 이내에 사용되는 일회용 점막 세척액인 것이 바람직하다. In the present invention, it is preferable that the mucosal washing liquid is a disposable mucous membrane washing solution used within 1 to 2 days after opening because dissolved oxygen is dissolved at a high concentration after opening.

본 발명에 있어서, 상기 점막 세척액은 염화세칠피리디늄, 불소, 유칼립톨(U.S.P), L-멘톨(약전), 치몰(약전), 살리실산메칠(약전), 황산나트륨, 염화아연, Toothpast Flavor, 자일리톨, 향료, 녹차추출물 또는 Catechin 성분들과 같은 공지된 유용성분들을 하나 이상 포함할 수 있다. 이러한 성분들은 각각 0.01~1% 범위에서 사용될 수 있다.In the present invention, the mucosal washing solution is preferably selected from the group consisting of salicylic acid chloride, fluorine, eucalyptol (USP), L-menthol (pharmacopoeial), chimol (pharmacopoeial), salicylic acid methyl chloride, sodium sulfate, zinc chloride, , Fragrances, green tea extracts, or Catechin components. These components can be used in the range of 0.01 to 1%, respectively.

본 발명은 일 측면에서, 80 ppm 이상의 산소가 녹아있는 고농도 산소수가 들어 있는 밀봉된 점막 세척액 용기일수 있다. 상기 용기는 고농도로 용존된 산소와의 반응을 최소화하기 위해서 플라스틱 병인 것이 바람직하다. The present invention, in one aspect, can be a sealed mucosal wash liquid container containing a high concentration of oxygen dissolved in oxygen of at least 80 ppm. The container is preferably a plastic bottle in order to minimize the reaction with oxygen dissolved at a high concentration.

본 발명은 일 측면에서, 눈에 80 ppm 이상의 고농도 산소수으로 구강 또는 비강의 점막을 세척하여, 비염이나 가래, 천식과 같은 질병을 치료하는 방법을 제공한다. In one aspect, the present invention provides a method for treating diseases such as rhinitis, sputum and asthma by washing oral or nasal mucosa with high-concentration oxygen water of 80 ppm or more in the eye.

본 발명에 따른 고농도 산소수는 다양한 방식으로 제조될 수 있다. The high oxygen concentration water according to the present invention can be prepared in various ways.

본 발명의 바람직한 실시에 있어서, 상기 고농도 산소수는 산소를 미세기포로 만들어서 물에 용해시켜 제조될 수 있다. 미세 기포 발생장치는 본 발명에서 참고문헌으로 통합된 서울 대학교 산학협력단에 허여된 특허 제1332370호 "미세기포 발생장치"나 제1396494호 "미세기포 발생장치"를 사용할 수 있다.In a preferred embodiment of the present invention, the high-concentration oxygen water can be prepared by making oxygen into a fine particle and dissolving it in water. The micro-bubble generator may be a micro-bubble generator or a micro-bubble generator disclosed in Korean Patent No. 1332370, which is incorporated herein by reference in its entirety.

본 발명은 고농도 산소수로 이루어진 점막 세척액을 이용하여 비강 또는 구강을 세척하여 점막에 직접적으로 산소를 공급하여 점막 및 점막에 형성된 섬모의 기능을 활성화시킬 수 있다. The present invention can activate the function of cilia formed in mucosa and mucosa by supplying nasal mucosa or oral cavity with mucosal washing solution made of high concentration oxygen water and supplying oxygen directly to mucous membrane.

또한, 본 발명에 따른 점막 세척액은 물과 동일한 성분으로 이루어져 장시간 반복적으로 사용하더라도 인공적인 화학 약품에 의한 부작용을 최소화할 수 있다. In addition, the mucosal washing solution according to the present invention is composed of the same components as water and can minimize adverse effects caused by artificial chemicals even if it is used repeatedly for a long time.

또한, 본 발명에 따른 점막 세척액은 물에 용존된 고농도의 산소가 점막에 있는 각종 염증 등을 치료하여 비염 또는 목감기등의 증상을 효과적으로 완화시킬 수 있다. In addition, the mucosal washing solution according to the present invention can effectively relieve symptoms such as rhinitis or throat, by treating various inflammation and the like, which are dissolved in water and have a high concentration of oxygen in the mucous membrane.

이하, 실시예를 통해서 발명을 상세하게 설명한다. 하기 실시예는 본 발명을 한정하기 위한 것은 아니면, 본 발명을 예시하기 위한 것이다. Hereinafter, the present invention will be described in detail by way of examples. The following examples are intended to illustrate but not limit the present invention.

구강 세척제 평가Assessment of mouthwash

실시예 1.Example 1.

100 ±20 ppm의 산소가 물에 녹아 있는 고농도 산소수를 제조하고, 자일리톨, 향료, 녹차추출물을 각각 0.1%씩 혼합하여 고농도 산소수를 포함하는 구강 세척제를 제조하였다. Highly concentrated oxygenated water with 100 ± 20 ppm of oxygen dissolved in water was prepared and mixed with 0.1% each of xylitol, flavor and green tea extract to prepare a mouthwash containing high concentration oxygenated water.

실험군 10인에게는 물 100 ml로 먼저 세척하게 한 후, 실시예 1에 따라 제조된 구강 세척제로 가글링을 하도록 하였으며, 관능 검사를 실시하였다. 물에 비해서 상쾌한 기분을 느낄 경우, ○, 유사할 경우 △, 나쁠 경우 ×로 평가하였다. 평가 결과를 표 1에 결과를 도시하였다.Ten people in the experimental group were firstly rinsed with 100 ml of water, followed by gagging with the mouthwash prepared according to Example 1, and the sensory test was performed. When the user felt a refreshing feeling with respect to water, the results were evaluated as " o ", " similarity ", and " bad " The evaluation results are shown in Table 1.

실시예 2.Example 2.

200 ±20 ppm의 산소가 물에 녹아 있는 고농도 산소수를 제조하고, 자일리톨, 향료, 녹차추출물을 각각 0.1%씩 혼합하여 고농도 산소수를 포함하는 구강 세척제를 제조하였다. Highly concentrated oxygenated water containing 200 ± 20 ppm of oxygen dissolved in water was prepared and 0.1% of each of xylitol, flavor and green tea extract was mixed to prepare a mouthwash containing high concentration oxygenated water.

실험군 10인에게는 물 100 ml로 먼저 세척하게 한 후, 실시예 1에 따라 제조된 구강 세척제로 가글링을 하도록 하였으며, 관능 검사를 실시하였다. 물에 비해서 상쾌한 기분을 느낄 경우, ○, 유사할 경우 △, 나쁠 경우 ×로 평가하였다. 평가 결과를 표 1에 결과를 도시하였다.Ten people in the experimental group were firstly rinsed with 100 ml of water, followed by gagging with the mouthwash prepared according to Example 1, and the sensory test was performed. When the user felt a refreshing feeling with respect to water, the results were evaluated as " o ", " similarity ", and " bad " The evaluation results are shown in Table 1.

비교 실시예 1Comparative Example 1

정제수에 자일리톨, 향료, 녹차추출물을 각각 0.1%씩 혼합하여 대조군 구강 세척제를 제조하였다. The control mouthwash was prepared by mixing 0.1% xylitol, fragrance, and green tea extract in purified water.

대조군 10인에게는 물 100 ml로 먼저 세척하게 한 후, 비교 실시예 1에 따라 제조된 구강 세척제로 가글링을 하도록 하였으며, 관능 검사를 실시하였다. 물에 비해서 상쾌한 기분을 느낄 경우, ○, 유사할 경우 △, 나쁠 경우 ×로 평가하였다. 평가 결과를 표 1에 결과를 도시하였다. 10 persons in the control group were first washed with 100 ml of water, followed by gagging with the mouthwash prepared according to Comparative Example 1. The sensory test was performed. When the user felt a refreshing feeling with respect to water, the results were evaluated as " o ", " similarity ", and " bad " The evaluation results are shown in Table 1.

관능 평가Sensory evaluation 실시예 1Example 1 실시예 2Example 2 비교에Compare to 77 99 22 33 1One 77 ×× 00 00 1One

비강 세척성 평가Nasal washability evaluation

실시예 3.Example 3.

100 ±20 ppm의 산소가 물에 녹아 있는 고농도 산소수를 제조하고, 자일리톨, 향료, 녹차추출물을 각각 0.1%씩 혼합하여 고농도 산소수를 포함하는 비강 세척제를 제조하였다. 물에 죽염을 투입하여 0.9 % 농도로 만들었다.Highly concentrated oxygen water containing 100 ± 20 ppm of oxygen dissolved in water was prepared and 0.1% of each of xylitol, flavor and green tea extract was mixed to prepare a nasal wash containing high concentration oxygenated water. Bamboo salt was added to the water to make the concentration of 0.9%.

실험군 10인에게는 물 50 ml를 비강 스프레이에 담아서 코속에 뿌려서 관능 검사를 실시하였다. 물에 비해서 상쾌한 기분을 느낄 경우, ○, 유사할 경우 △, 나쁠 경우 ×로 평가하였다. 평가 결과를 표 2에 결과를 도시하였다.For 10 persons in the experimental group, 50 ml of water was put into a nasal spray and sprinkled on the coil to perform a sensory test. When the user felt a refreshing feeling with respect to water, the results were evaluated as " o ", " similarity ", and " bad " The evaluation results are shown in Table 2.

실시예 4.Example 4.

200 ±20 ppm의 산소가 물에 녹아 있는 고농도 산소수를 제조하고, 자일리톨, 향료, 녹차추출물을 각각 0.1%씩 혼합하여 고농도 산소수를 포함하는 비강 세척제를 제조하였다. 물에 죽염을 투입하여 0.9 % 농도로 만들었다.Highly concentrated oxygen water containing 200 ± 20 ppm of oxygen dissolved in water was prepared and a nasal wash containing high concentration oxygenated water was prepared by mixing xylitol, fragrance and green tea extract with 0.1% each. Bamboo salt was added to the water to make the concentration of 0.9%.

실험군 10인에게는 물 50 ml를 비강 스프레이에 담아서 코 속에 뿌려서 관능 검사를 실시하였다. 물에 비해서 상쾌한 기분을 느낄 경우, ○, 유사할 경우 △, 나쁠 경우 ×로 평가하였다. 평가 결과를 표 2에 결과를 도시하였다.In the experimental group, 50 ml of water was put into nasal spray and sprayed on the nose for sensory evaluation. When the user felt a refreshing feeling with respect to water, the results were evaluated as " o ", " similarity ", and " bad " The evaluation results are shown in Table 2.

관능 평가Sensory evaluation 실시예 3Example 3 실시예 4Example 4 77 88 33 22 ×× 1One 00

비염 완화 성능 시험Rinse mitigation performance test

실시예 5Example 5

200 ±20 ppm의 산소가 물에 녹아 있는 고농도 산소수를 제조하고, 자일리톨, 향료, 녹차추출물을 각각 0.1%씩 혼합하여 고농도 산소수를 포함하는 비강 세척제를 제조하였다. 물에 죽염을 투입하여 0.9 % 농도로 만들었다.Highly concentrated oxygen water containing 200 ± 20 ppm of oxygen dissolved in water was prepared and a nasal wash containing high concentration oxygenated water was prepared by mixing xylitol, fragrance and green tea extract with 0.1% each. Bamboo salt was added to the water to make the concentration of 0.9%.

제조된 고농도 비강 세척수를 비염으로 점막이 부풀어 콧물이 흐르는 사람의 비강에 1일 3회, 4시간 간격으로 적정량 뿌려주었다. 3일 사용 후 증상 완화에 대한 관능 시험을 실시하였다. 시험 참여자는 총 10인이었다. 비염이 개선된 경우 ○, 유사할 경우 △, 나쁠 경우 ×로 평가하였다. 평가 결과는 표 3에 나타내었다.The mucous membranes were swollen with rhinitis, and the nasal cavity was infused into the nasal cavities of the nasal cavity three times a day, every 4 hours. After 3 days of use, a sensory test for symptom relief was performed. The total number of participants was 10. The evaluation was evaluated as? When the rhinitis was improved,? When it was similar, and X when it was bad. The evaluation results are shown in Table 3.

비교 실시예 5Comparative Example 5

정제수에 자일리톨, 향료, 녹차추출물을 각각 0.1%씩 혼합하여 비강 세척제를 제조하였다. 물에 죽염을 투입하여 0.9 % 농도로 만들었다.The nasal washings were prepared by mixing 0.1% xylitol, fragrance and green tea extract in purified water. Bamboo salt was added to the water to make the concentration of 0.9%.

제조된 비강 세척수를 비염으로 점막이 부풀어 콧물이 흐르는 사람의 비강에 1일 3회, 4시간 간격으로 적정량 뿌려주었다. 3일 사용 후 증상 완화에 대한 관능 시험을 실시하였다. 시험 참여자는 총 10인이었다. 비염이 개선된 경우 ○, 유사할 경우 △, 나쁠 경우 ×로 평가하였다. 평가 결과는 표 3에 나타내었다.The manufactured nasal wash water was swollen with rhinitis and sprayed into the nasal cavity of a man with runny nose three times a day, every 4 hours. After 3 days of use, a sensory test for symptom relief was performed. The total number of participants was 10. The evaluation was evaluated as? When the rhinitis was improved,? When it was similar, and X when it was bad. The evaluation results are shown in Table 3.

관능평가Sensory evaluation 실시예 5Example 5 비교실시예 5Comparative Example 5 66 1One 33 66 ×× 1One 33

Claims (4)

비강 및/또는 구강의 세척에 사용하는 세척액에 있어서,
상기 세척액은 80 ppm 이상의 고농도 산소를 유효성분으로 포함하는 것을 특징으로 하는 세척액.
In a washing solution used for washing nasal and / or oral cavity,
Characterized in that the cleaning liquid contains oxygen at a concentration of 80 ppm or more as an active ingredient.
제1항에 있어서, 상기 세척액에는 소금을 더 포함하는 것을 특징으로 하는 세척액. The cleaning solution according to claim 1, wherein the cleaning solution further comprises salt. 제1항 또는 제2항에 있어서, 상기 세척액은 밀폐용 용기에 보관된 것을 특징으로 하는 세척액. The cleaning solution according to claim 1 or 2, wherein the cleaning solution is stored in a sealing container. 80 ppm 이상의 고농도 산소를 유효성분으로 하는 고농도 산소수를 이용하여 비강 및/또는 구강을 세척하여 염증을 개선하는 것을 특징으로 하는 방법.Characterized in that the nasal and / or oral cavity is washed using high-concentration oxygen water containing 80 ppm or more of high concentration oxygen as an active ingredient to improve inflammation.
KR1020160074828A 2016-06-16 2016-06-16 Mouth and nose cleaning liquid comprising oxygen KR20170141870A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210125706A (en) * 2020-04-09 2021-10-19 이정현 Oral cleansing composition
KR20220030555A (en) * 2020-09-03 2022-03-11 중앙대학교 산학협력단 Mouth cleaner comprising oxygen nano bubbles and method of fabricating the same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210125706A (en) * 2020-04-09 2021-10-19 이정현 Oral cleansing composition
KR20220030555A (en) * 2020-09-03 2022-03-11 중앙대학교 산학협력단 Mouth cleaner comprising oxygen nano bubbles and method of fabricating the same

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