KR20170045750A - 폐 사르코이드증 치료 방법 - Google Patents

폐 사르코이드증 치료 방법 Download PDF

Info

Publication number
KR20170045750A
KR20170045750A KR1020177009617A KR20177009617A KR20170045750A KR 20170045750 A KR20170045750 A KR 20170045750A KR 1020177009617 A KR1020177009617 A KR 1020177009617A KR 20177009617 A KR20177009617 A KR 20177009617A KR 20170045750 A KR20170045750 A KR 20170045750A
Authority
KR
South Korea
Prior art keywords
patient
treatment
leu
ala
dnase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020177009617A
Other languages
English (en)
Korean (ko)
Inventor
베리 번스
Original Assignee
고담 바이오파마슈티컬스 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 고담 바이오파마슈티컬스 인크. filed Critical 고담 바이오파마슈티컬스 인크.
Publication of KR20170045750A publication Critical patent/KR20170045750A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/21—Endodeoxyribonucleases producing 5'-phosphomonoesters (3.1.21)
    • C12Y301/21001—Deoxyribonuclease I (3.1.21.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020177009617A 2014-09-08 2015-09-04 폐 사르코이드증 치료 방법 Withdrawn KR20170045750A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462047361P 2014-09-08 2014-09-08
US62/047,361 2014-09-08
PCT/US2015/048606 WO2016040169A2 (en) 2014-09-08 2015-09-04 Methods of treating pulmonary sarcoidosis

Publications (1)

Publication Number Publication Date
KR20170045750A true KR20170045750A (ko) 2017-04-27

Family

ID=54697634

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177009617A Withdrawn KR20170045750A (ko) 2014-09-08 2015-09-04 폐 사르코이드증 치료 방법

Country Status (11)

Country Link
US (2) US9402884B2 (OSRAM)
EP (1) EP3191090A2 (OSRAM)
JP (1) JP2017527618A (OSRAM)
KR (1) KR20170045750A (OSRAM)
CN (1) CN107249621A (OSRAM)
AU (1) AU2015315455A1 (OSRAM)
BR (1) BR112017004533A2 (OSRAM)
CA (1) CA2960622A1 (OSRAM)
IL (1) IL250980A0 (OSRAM)
MX (1) MX2017002948A (OSRAM)
WO (1) WO2016040169A2 (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3351263A1 (en) 2017-01-20 2018-07-25 Universitätsklinikum Hamburg-Eppendorf Pharmaceutical preparation for treating or preventing tissue adhesion
ES3008982T3 (en) 2017-08-18 2025-03-25 Neutrolis Inc Engineered dnase enzymes and use in therapy
EP3864147A4 (en) 2018-10-08 2022-07-06 Neutrolis, Inc. MANIPULATION OF DNASE ENZYMES FOR MANUFACTURE AND THERAPY
US11058724B2 (en) 2018-10-08 2021-07-13 Neutrolis, Inc. Methods of using DNASE1-like 3 in therapy
US10988746B2 (en) 2018-10-08 2021-04-27 Neutrolis, Inc. Manufacturing and engineering of DNASE enzymes for therapy
US11352613B2 (en) 2019-02-04 2022-06-07 Neutrolis, Inc. Engineered human extracellular DNASE enzymes
JP2022521600A (ja) * 2019-02-22 2022-04-11 シラ セラピューティック インコーポレイティッド 吸入可能な治療剤
WO2024197201A1 (en) * 2023-03-22 2024-09-26 The Regents Of The University Of California Systems and methods for the quantitative assessment of airway mucus plug pathology
US20260109959A1 (en) * 2025-01-18 2026-04-23 Brian William Davies Methods of treating pulmonary sarcoidosis with dna nucleases

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6348343B2 (en) * 1995-02-24 2002-02-19 Genentech, Inc. Human DNase I variants
EP1004302A3 (en) * 1998-10-29 2003-06-04 Ajinomoto Co., Inc. Immunomodulator
JP2007230919A (ja) * 2006-03-01 2007-09-13 Ki Pharma Kk 美白剤
MX2010000826A (es) * 2007-08-03 2010-03-01 Ucb Pharma Sa Derivados de sulfanilo y su uso como intermediarios de sintesis.
US8236786B2 (en) * 2008-08-07 2012-08-07 Pulmagen Therapeutics (Inflammation) Limited Respiratory disease treatment
DK2222272T3 (da) * 2008-08-07 2013-02-11 Pulmagen Therapeutics Inflammation Ltd Behandling af luftvejssygdom
GB201111485D0 (en) * 2011-07-05 2011-08-17 Biocopea Ltd Drug composition and its use in therapy
GB201014391D0 (en) * 2010-08-27 2010-10-13 Biocopea Ltd Drug composition and its use in therapy
GB201002224D0 (en) * 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment

Also Published As

Publication number Publication date
CA2960622A1 (en) 2016-03-17
WO2016040169A2 (en) 2016-03-17
IL250980A0 (en) 2017-04-30
US20160067317A1 (en) 2016-03-10
EP3191090A2 (en) 2017-07-19
JP2017527618A (ja) 2017-09-21
BR112017004533A2 (pt) 2018-05-08
WO2016040169A3 (en) 2016-05-26
US9402884B2 (en) 2016-08-02
CN107249621A (zh) 2017-10-13
AU2015315455A1 (en) 2017-04-27
US20170368150A1 (en) 2017-12-28
MX2017002948A (es) 2017-08-15

Similar Documents

Publication Publication Date Title
US9402884B2 (en) Methods of treating pulmonary sarcoidosis
CN107847615B (zh) 用于治疗cln2疾病的tpp1调配物及方法
EP2275086A1 (en) Reduced volume formulation of glatiramer acetate and methods of administration
Urata et al. Treating to target matrix metalloproteinase 3 normalisation together with disease activity score below 2.6 yields better effects than each alone in rheumatoid arthritis patients: T-4 Study
AU2014249531B2 (en) Use of levocetirizine and montelukast in the treatment of traumatic injury
Reid Osteoporosis treatment: focus on safety
EA034864B1 (ru) Способ лечения эозинофильной астмы со степенью тяжести от умеренной до тяжёлой
JP6134722B2 (ja) アミノピリジンを使用する脳卒中関連性の感覚運動障害を処置する方法
JP2026048915A (ja) プレカリクレイン関連の状態を治療及び予防するための組成物及び方法
Greulich et al. Safety of biweekly alpha1 antitrypsin treatment in the RAPID program
CN121816187A (zh) 用非妥西兰治疗血友病a
JP3916563B2 (ja) P物質の投与を含む治療方法
WO2026040961A1 (zh) pUDK-HGF注射液的用途
Jaclyn Smith Gefapixant, a P2X3 receptor antagonist, for the treatment of chronic cough Jaclyn A. Smith, Ph. D. 1, Michael M. Kitt, MD 2, Alyn H. Morice, MD 3, Surinder S. Birring, MD 4, Lorcan P. McGarvey, MD 5, Mandel R. Sher, MD 6, Yu-Ping Li, Ph. D. 7, Wen-Chi Wu, Ph. D. 2, Zhi Jin Xu, Ph. D. 2, David R. Muccino, MD 2, Anthony P. Ford, Ph. D. 2 on behalf of the Protocol 012 Investigators
Sanchez et al. 4CPS-193 Descriptive real-world outcomes with aflibercept 8 mg/0.07 ml in wet age-related macular degeneration and diabetic macular oedema
JP2024535467A5 (OSRAM)
HK40100646A (en) Use of anti-pro/latent myostatin antibody for treating spinal muscular atrophy
HK40100646B (en) Use of anti-pro/latent myostatin antibody for treating spinal muscular atrophy
Progressiva et al. THE MEDICAL MANAGEMENT OF FIBRODYSPLASIA OSSIFICANS PROGRESSIVA: CURRENT TREATMENT CONSIDERATIONS
Morice et al. Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough
HK1152249B (en) Reduced volume formulation of glatiramer acetate and methods of administration

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20170407

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination