KR20160146220A - Meibomian photographing gland device using infrared ray and meibomian gland photographing method using the same - Google Patents

Meibomian photographing gland device using infrared ray and meibomian gland photographing method using the same Download PDF

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KR20160146220A
KR20160146220A KR1020150083182A KR20150083182A KR20160146220A KR 20160146220 A KR20160146220 A KR 20160146220A KR 1020150083182 A KR1020150083182 A KR 1020150083182A KR 20150083182 A KR20150083182 A KR 20150083182A KR 20160146220 A KR20160146220 A KR 20160146220A
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light source
image
spring
camera
photographing
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KR1020150083182A
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KR101742049B1 (en
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황호식
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한림대학교 산학협력단
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/13—Ophthalmic microscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14—Arrangements specially adapted for eye photography

Abstract

An embodiment of the present invention relates to an infrared myalobrax imaging device and a method of photographing a myaloscope, and a technical problem to be solved is to make it possible to take a photograph of a myalp spring so that there is no part that can not be seen by reflection.
To this end, an embodiment of the present invention includes a camera for photographing My spring spring; A first light source provided at one side of the camera and emitting infrared rays toward the My spring spring; A second light source provided on the other side opposite to the one side of the camera to emit infrared rays toward the My spring spring; A controller for setting time information for emitting infrared rays of the first light source and the second light source and operating the first light source and the second light source according to the time information after operating the camera; And an image processing unit for generating and outputting a mavograft image obtained by automatically synthesizing a first image by the first light source and a second image by the second light source.

Description

BACKGROUND OF THE INVENTION Field of the Invention [0001] The present invention relates to an apparatus for photographing an infra-red myeloma and a method for photographing a myeloma,

An embodiment of the present invention relates to an infrared megalospheres photographing apparatus and a method of photographing a myalobrax that can reduce a low-exposed area for a light source when photographing a myaloscope.

Meibomian gland is a kind of sebaceous gland in the eyelid that secretes fat component and forms an oil layer on the tear layer. In the presence of Meibomian gland dysfunction, the secretion of lipid components is reduced, resulting in excessive dryness of the tears and dry eye syndrome. To diagnose myalgia dysfunction, slit-lamp examination and myomaloscopy are necessary for eyelid and eye surface.

Previously, in order to activate the eyelid myalgia, a light source was placed on the skin side of the eyelid, the eyelid was turned over, and the image of the light passing through the skin and my spring was photographed (transillumination). However, specialists are needed for the examination, and since the light source touches the skin, there is a feeling of discomfort such as heat, glare, and the like.

1 is a view showing the structure of a slit lamp microscope for general ophthalmology.

1, the slit lamp microscope for ophthalmologic examination comprises a lens unit 10 arranged to face the subject 1 and allowing the visual observation of the conjunctiva or the image of the cornea 2 of the subject 1, A light source 30 for providing light to the subject 1, a magnification controller 40 for controlling the image magnification of the subject 1, a beam splitter 20 for distributing the image of the subject 1, .

The light source 30 of the slit lamp microscope is freely moved forward, backward, leftward and rightward in front of the cornea or conjunctiva 2 of the subject 1 so as to emit the eyeball in various directions, And the lens unit 10 is also rotated to the left and right so that the eye image can be brought to the center.

When the subject faces the forehead attaching portion 38 and the shoulder attaching portion 39 with the forehead and jaw respectively facing the forehead and the shoulder attaching portion 39, the examiner examines the light source 30 and the reflector 35 so that light is irradiated onto the cornea 2 of the eye 1 of the subject. And adjusts the position and magnification of the lens unit 10 such that the eye image of the subject is located at the center of the screen.

Further, a camera 50 for photographing an eyeball image distributed by the beam splitter 20 may be further provided above the beam splitter 20.

Since the configuration related to the lens unit 10, the beam splitter 20, the light source 30, the magnification adjuster 40, the camera 50 and the reflector 35 uses a configuration adopted in general slit-lamp microscopes for ophthalmology, A detailed description thereof will be omitted.

The apparatus for photographing the existing myo spring is mounted on a slit lamp microscope for ophthalmologic examination according to the related art as shown in FIG. 1, but in this case, severe reflection occurs depending on the position of the light source, There is a problem that a part that can not be seen easily occurs.

In addition, the apparatus for photographing the existing My spring spring has a problem in that, when one light source is used, one side of My spring spring is too bright to be seen and the other side is too dark to be seen.

Patent Registration No. 10-1259056 '3-D Myocardial Radiography Using Optical Coherence Tomography'

One embodiment of the present invention provides an apparatus for photographing my spring spots so that there is no part that can not be easily seen by reflection, and a method for photographing my spring spots.

According to an embodiment of the present invention, there is provided an apparatus for photographing an infra-red myeloma, A first light source provided at one side of the camera and emitting infrared rays toward the My spring spring; A second light source provided on the other side opposite to the one side of the camera to emit infrared rays toward the My spring spring; A controller for setting time information for emitting infrared rays of the first light source and the second light source and operating the first light source and the second light source according to the time information after operating the camera; And an image processor for generating and outputting a mie-view image in which a first image by the first light source and a second image by the second light source are automatically synthesized.

The camera may be an infrared-only camera equipped with an infrared pass filter.

The controller may be configured such that the second light source is not operated when the first light source is operated and the first light source is not operated when the second light source is operated.

And a moving unit moving the camera, the first light source, and the second light source back and forth, right and left, and up and down.

Wherein the image processing unit comprises: an image synthesizing unit for generating a myoglyphic image by automatically synthesizing a first image by the first light source and a second image by the second light source; An area calculation unit for calculating an area of the entire micro myocardium constituted by a plurality of myo-spring systems using the generated myographic images; A micronucleus number calculation unit for calculating the number of acinus in the myospasm using the generated myographic image; And a micronucleus size calculation unit for calculating an average and a standard deviation of the size of the micronucleus using the generated myographic image.

The image processing unit may further include an information output unit for outputting information about the generated myographic image, an area of the calculated my spring total, a number of the micronuclei of the calculated myonosphere and a size and a standard deviation of the micronucleus have.

According to another embodiment of the present invention, there is provided a method of photographing myauxmarma comprising the steps of: emitting a first infrared ray from a first light source toward a my spring region; A second step of photographing a first image with respect to the micro spring region using a camera; A third step of emitting a second infrared ray from a second light source which is located apart from the first light source toward the microsphere region; A fourth step of photographing a second image with respect to the micro spring region using the camera; And a fifth step of generating and outputting a mavograft image obtained by automatically synthesizing a first image by the first light source and a second image by the second light source.

A first step of setting time information for infrared emission of the first light source and the second light source before the first step; And a second process of photographing the my spring region using the camera.

A first step of generating a myographic image by automatically synthesizing a first image by the first light source and a second image by the second light source; A second step of calculating an area of the entire my spring spring constituted by a plurality of my spring springs using the generated myographic images; A third step of calculating the number of micinuclei (acinus) on the myospan using the generated myographic image; A fourth step of calculating an average and a standard deviation of the size of the micronucleus using the generated myographic image; And a fifth step of outputting information on the generated myographic image, the calculated area of the entire myelocampus, the calculated number of micronuclei of the myospasm, and the size and standard deviation of the micronucleus.

In the infrared myalobrax imaging device and the myo-spring imaging method according to an embodiment of the present invention, a face of a user is fixed to the device, a focus is applied to the my spring area, the camera is operated, and only the first light source is turned on MySpace photographing is performed, and after a predetermined time, only the second light source is turned on, and the MySpace photographing is performed to automatically synthesize the two images. By doing so, And can output a panoramic image.

1 is a view showing the structure of a slit lamp microscope for general ophthalmology.
FIG. 2 is a view showing an example of a prototype showing an infrared my myosin imaging apparatus according to an embodiment of the present invention.
FIG. 3 is a diagram illustrating the arrangement of cameras and light sources of an infrared myosseam photographing apparatus according to an embodiment of the present invention.
FIG. 4 is a schematic view of an apparatus for photographing an infrared myalobrax according to an embodiment of the present invention.
5 is a block diagram schematically showing the image processing unit of FIG.
FIG. 6 is a view showing a myographic image in which a first image and a second image are synthesized by the image processing unit of FIG. 4;
FIG. 7 is a flowchart illustrating an infrared myaloblastic imaging method according to another embodiment of the present invention.

The terms used in this specification will be briefly described and the present invention will be described in detail.

While the present invention has been described in connection with what is presently considered to be the most practical and preferred embodiment, it is to be understood that the invention is not limited to the disclosed embodiments. Also, in certain cases, there may be a term selected arbitrarily by the applicant, in which case the meaning thereof will be described in detail in the description of the corresponding invention. Therefore, the term used in the present invention should be defined based on the meaning of the term, not on the name of a simple term, but on the entire contents of the present invention.

When an element is referred to as "including" an element throughout the specification, it is to be understood that the element may include other elements as well, without departing from the spirit or scope of the present invention. Furthermore, the term "part" or the like described in the specification means a unit for processing at least one function or operation, which may be implemented by hardware or software, or a combination of hardware and software.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings so that those skilled in the art can easily carry out the present invention. The present invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. In order to clearly illustrate the present invention, parts not related to the description are omitted, and similar parts are denoted by like reference characters throughout the specification.

FIG. 2 is a view showing an example of a prototype of an infrared myaloscope apparatus according to an embodiment of the present invention. FIG. 3 is a schematic view showing an arrangement of cameras and light sources of an infrared 4 is a block diagram schematically showing the image processing unit of FIG. 4, and FIG. 6 is a block diagram of the image processing unit of FIG. 4 according to an embodiment of the present invention. FIG. 5 is a view showing a mvoghraphic image in which a first image and a second image are synthesized by an image processing unit. FIG.

Referring to FIGS. 2 to 4, the infrared myalysis apparatus 100 according to an exemplary embodiment of the present invention is an apparatus for photographing myalgia, which is a secretory gland located in an eyelid of a subject, 1 includes a light source 120, a second light source 130, a control unit 140, an image processing unit 150, and a moving unit 160.

The infrared myosseam photographing apparatus 100 is a stand alone apparatus which includes a main body 101 disposed to be opposed to an object to be inspected, an infrared-dedicated camera 100 having an infrared pass filter (blocking other visible light) A first light source 120 and a second light source 130 that emit infrared rays are provided on both sides of the infrared ray camera 110. The infrared ray camera 110 and the first light source 120 And a photographing button (not shown) for operating the second light source 130 are provided. In addition, the infrared myosseam photographing apparatus 100 includes fixing means (not shown) for fixing a face of a patient as in a conventional slit lamp microscope apparatus for ophthalmologic examination, (Not shown) that moves in the front-rear direction so as to focus the subject, and a focus adjusting unit (not shown) that adjusts the focus of the subject. However, since these configurations are essential to the inspection equipment for inspecting the inspection subject, detailed description thereof will be omitted.

The camera 110 is a camera device for photographing My spring spring, and may be an infrared-only camera equipped with an infrared ray pass filter (not shown). The infrared ray camera is equipped with an infrared ray filter for filtering the visible ray to radiate only the infrared rays emitted by the first light source 120 and the second light source 130 and reflected by the eyelids of the subject.

The first light source 120 is provided on one side of the camera 110 and emits infrared rays toward the My spring spring.

The second light source 130 is provided on the other side opposite to the one side of the camera 110, and emits infrared rays toward the My spring.

The first light source 120 and the second light source 130 may be spaced from each other by an interval of 30 to 150 mm in a state of being horizontally arranged with respect to the camera 110, .

The first light source 120 and the second light source 130 irradiate an infrared ray toward the My spring core so as to form a 30 ° to 60 ° angle with respect to the front surface of the camera 110.

The control unit 140 sets time information for emitting infrared rays of the first light source 120 and the second light source 130 and operates the camera 110 so that the first light source 120, Two light sources 130 are sequentially operated. When the first light source 120 is operated, the controller 140 does not operate the second light source 130, and when the second light source 130 operates, the controller 140 sets the first light source 120 to be inoperative .

The image processor 150 generates and outputs a mie-view image obtained by automatically synthesizing a first image by the first light source 120 and a second image by the second light source 130.

5, the image processor 150 includes an image synthesizer 151, an area calculator 152, a micronucleus calculator 153, a micronucleus size calculator 154, (155).

The image synthesizing unit 151 generates a myographic image in which a first image by the first light source 120 and a second image by the second light source 130 are automatically synthesized. That is, the image synthesizer 151 generates a mie-view image in which the first image and the second image are automatically synthesized based on the outline of the upper and lower eyelids.

The area calculation unit 152 calculates an area of the entire Myux spring including a plurality of my spring gasses using the myographic image generated by the image synthesis unit 151. [ The area calculation unit 152 may calculate an area of only the my spring M shown in FIG. 6 by using a predetermined area calculation algorithm and may calculate the area of the contour including the my spring M, M) can also be calculated.

More specifically, the area calculation unit 152 calculates the area and the area of the Myo spring using the ratio of the length to the actual length in the myographic image generated by the image synthesis unit 151 using the area calculation algorithm . Here, the actual length is information actually measured by the length measuring means in advance. Since the area where the micronucleus is present in the myosomes is bright compared with the area in which the micronucleus is absent, the area calculation unit 152 automatically sets the threshold value of the brightness through the area calculation algorithm, And can calculate the respective areas. The total area of the Myo spring can be calculated by adding the respective areas calculated in this manner.

The micronucleus number calculation unit 153 calculates the number of micronucleus (acinus) on the myo spring using the myographic image generated by the image synthesis unit 151. That is, the micronucleus number calculator 153 automatically calculates the number of micronuclei in one my spring in the myographic image.

The micronucleus size calculator 154 calculates an average and a standard deviation of micronucleus sizes using the myographic images generated by the image synthesizer 151.

The information output unit 155 outputs the mibo-graphic image generated by the image synthesis unit 151, the area of the entire micro-spring calculated by the area calculation unit 152, Outputs information about the number of micronuclei in myosomes and the size and standard deviation of micronuclei. The information output unit 155 may be any one of an LCD (Liquid Crystal Display), an LED (Liquid Emitting Diode), an OLED (Organic LED), and an AMOLED (Active Matrix OLED) Can be used.

First, when the examiner presses the photographing button provided on the main body 101, the controller 140 controls the infrared light source 100 to irradiate the infrared light from the first light source 120) is turned on, and the microsampler is photographed in a state in which only the second light source 120 is turned on for a very short time (for example, 0.1 second). Then, the two images are automatically synthesized through the image processing unit 150, and then a myographical image which is not visible due to excessive reflections or is too dark to be viewed is output. At this time, the image processing unit 150 can calculate the area of the entire my spring, the size of the micronucleus, and the size and standard deviation of the micronucleus using the myographic image.

The moving unit 160 has a function of moving the camera 110, the first light source 120, and the second light source 130 to move back and forth, left and right, and up and down to photograph My Spring, which is a secretion located in the eyelid of the subject, .

An infrared myalobrax imaging method for photographing my spring spots using the infrared mycolumbar apparatus 100 according to an embodiment of the present invention will be described with reference to FIG.

FIG. 7 is a flowchart illustrating an infrared myaloblastic imaging method according to another embodiment of the present invention.

Referring to FIG. 7, a method of infrared micro myomectomy according to another embodiment of the present invention includes a first step (S10) of emitting a first infrared ray from a first light source toward a micro-spring region, A third step S30 of emitting a second infrared ray from the second light source positioned away from the first light source toward the micro spring region, A fourth step S40 of photographing a second image with respect to the region, and a fifth step S40 of generating and outputting a mavograft image obtained by automatically synthesizing a first image by the first light source and a second image by the second light source, And steps S50 and S60.

In addition, the present infrared infra-red myosseous imaging method includes a time information setting process for setting time information for emitting infrared rays of the first light source and the second light source before the first step S10, An imaging process can be performed.

In addition, the fifth step S50 and S60 may include an image generation step of generating a myographic image in which a first image by the first light source and a second image by the second light source are automatically synthesized, An area calculation process for calculating the area of the entire my spring total consisting of a plurality of my spring gasses using the generated myvography image, a microvolume image generated during the image generation process, A micronucleus size calculation process for calculating the mean and standard deviation of the size of the micronucleus using the generated myographic images generated during the image generation process, , The area of the entire my spring total calculated in the area calculation process, the number of micronuclei in micronucleus calculated in the calculation process of micronucleus, and the size and standard deviation of micronuclei It may comprise the output information output process.

The fifth step (S50, S60) of generating and outputting a mibo-graphic image in which a first image by the first light source and a second image by the second light source are automatically synthesized, and the like It is possible to embody computer-readable code on a computer-readable recording medium. A computer-readable recording medium includes all recording apparatuses in which data read by a computer is stored. Examples of the computer-readable recording medium include a ROM, a RAM, a CD-ROM, a magnetic tape, an optical data storage device, and the like, and a carrier wave (for example, transmission via the Internet). The computer readable recording medium may also be distributed over a networked computer system so that computer readable code can be stored and executed in a distributed manner.

According to the infrared myalobrax imaging apparatus and the myaloscope imaging method configured as described above, the user's face is fixed to the equipment, the focus is focused on the my spring region, the camera is operated, MySpace photographing is performed in a state that only the light source is turned on, and MySpace photographing is performed in a state in which only the second light source is turned on after a predetermined time, so that the two images are automatically synthesized, It is possible to output a myographic image without an invisible area.

The present invention is not limited to the above-described embodiment, but may be applied to various other types of apparatuses such as the one disclosed in the following claims It will be understood by those of ordinary skill in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined in the appended claims.

100: infrared mycolumbar radiographing apparatus 101:
110: camera 120: first light source
130: second light source 140:
150: image processor 151:
152: area calculation unit 153: micronucleus number calculation unit
154: Micronucleus size calculation unit 155: Information output unit
160:

Claims (9)

A camera for photographing my spring spring;
A first light source provided at one side of the camera and emitting infrared rays toward the My spring spring;
A second light source provided on the other side opposite to the one side of the camera to emit infrared rays toward the My spring spring;
A controller for setting time information for emitting infrared rays of the first light source and the second light source and operating the first light source and the second light source according to the time information after operating the camera; And
And an image processor for generating and outputting a mie-graft image obtained by automatically synthesizing a first image by the first light source and a second image by the second light source.
The method according to claim 1,
Wherein the camera is an infrared-only camera equipped with an infrared pass filter.
The method according to claim 1,
Wherein the controller sets the second light source not to operate when the first light source is operated and prevents the first light source from operating when the second light source is operated.
The method according to claim 1,
Further comprising a moving unit for moving the camera, the first light source, and the second light source back and forth, right and left, and up and down.
The method according to claim 1,
The image processing unit
An image synthesizer for generating a myoglyphic image in which a first image by the first light source and a second image by the second light source are automatically synthesized;
An area calculation unit for calculating an area of the entire micro myocardium constituted by a plurality of myo-spring systems using the generated myographic images;
A micronucleus number calculation unit for calculating the number of acinus in the myospasm using the generated myographic image;
And a micronucleus size calculation unit for calculating an average and a standard deviation of the size of the micronucleus using the generated myographic image.
The method of claim 5,
The image processing unit may further include an information output unit for outputting information about the generated myographic image, an area of the calculated total myelocapsular region, information on the number of micronuclei of the calculated myonosphere and the size and standard deviation of the micronucleus Characterized in that the infrared megasseum photographing device comprises:
A first step of emitting a first infrared ray from the first light source toward the myo spring region;
A second step of photographing a first image with respect to the micro spring region using a camera;
A third step of emitting a second infrared ray from a second light source which is located apart from the first light source toward the microsphere region;
A fourth step of photographing a second image with respect to the micro spring region using the camera; And
And a fifth step of generating and outputting a mie-graft image obtained by automatically synthesizing a first image by the first light source and a second image by the second light source.
The method of claim 7,
Before the first step
A first step of setting time information for infrared emission of the first light source and the second light source; And
And a second process of photographing the my spring region using the camera is performed.
The method of claim 7,
The fifth step
A first step of generating a myographic image by automatically synthesizing a first image by the first light source and a second image by the second light source;
A second step of calculating an area of the entire my spring spring constituted by a plurality of my spring springs using the generated myographic images;
A third step of calculating the number of micinuclei (acinus) on the myospan using the generated myographic image;
A fourth step of calculating an average and a standard deviation of the size of the micronucleus using the generated myographic image; And
And a fifth step of outputting information on the generated myographical image, the calculated area of the entire myelospasm, the number of the micronuclei of the calculated myospasm and the size and standard deviation of the micronucleus. How to shoot my spring.
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