KR20160090284A - 이동 및 타이밍 제어를 위한 시스템 및 방법 - Google Patents

이동 및 타이밍 제어를 위한 시스템 및 방법 Download PDF

Info

Publication number
KR20160090284A
KR20160090284A KR1020167009683A KR20167009683A KR20160090284A KR 20160090284 A KR20160090284 A KR 20160090284A KR 1020167009683 A KR1020167009683 A KR 1020167009683A KR 20167009683 A KR20167009683 A KR 20167009683A KR 20160090284 A KR20160090284 A KR 20160090284A
Authority
KR
South Korea
Prior art keywords
substrate
reagent
chamber
unit
blocking unit
Prior art date
Application number
KR1020167009683A
Other languages
English (en)
Korean (ko)
Inventor
러스템 에프. 이즈마길로브
펭 쉔
리앙 리
데이비드 슬렉
조 바커
에스피르 카하트
크리스 다 코스타
Original Assignee
캘리포니아 인스티튜트 오브 테크놀로지
슬립칩 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 캘리포니아 인스티튜트 오브 테크놀로지, 슬립칩 코포레이션 filed Critical 캘리포니아 인스티튜트 오브 테크놀로지
Publication of KR20160090284A publication Critical patent/KR20160090284A/ko

Links

Images

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52Containers specially adapted for storing or dispensing a reagent
    • B01L3/527Containers specially adapted for storing or dispensing a reagent for a plurality of reagents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52Containers specially adapted for storing or dispensing a reagent
    • B01L3/523Containers specially adapted for storing or dispensing a reagent with means for closing or opening
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/4077Concentrating samples by other techniques involving separation of suspended solids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0605Metering of fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0642Filling fluids into wells by specific techniques
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0684Venting, avoiding backpressure, avoid gas bubbles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0689Sealing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16Reagents, handling or storing thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/042Caps; Plugs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/044Connecting closures to device or container pierceable, e.g. films, membranes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/045Connecting closures to device or container whereby the whole cover is slidable
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/046Function or devices integrated in the closure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/046Function or devices integrated in the closure
    • B01L2300/047Additional chamber, reservoir
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0672Integrated piercing tool
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/069Absorbents; Gels to retain a fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867Multiple inlets and one sample wells, e.g. mixing, dilution
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874Three dimensional network
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/12Specific details about materials
    • B01L2300/123Flexible; Elastomeric
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/161Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1855Means for temperature control using phase changes in a medium
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1877Means for temperature control using chemical reactions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0457Moving fluids with specific forces or mechanical means specific forces passive flow or gravitation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0493Specific techniques used
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/0644Valves, specific forms thereof with moving parts rotary valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0677Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0677Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
KR1020167009683A 2013-09-18 2014-09-18 이동 및 타이밍 제어를 위한 시스템 및 방법 KR20160090284A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201361879487P 2013-09-18 2013-09-18
US61/879,487 2013-09-18
US201361917300P 2013-12-17 2013-12-17
US61/917,300 2013-12-17
US201461936275P 2014-02-05 2014-02-05
US61/936,275 2014-02-05
US201462035857P 2014-08-11 2014-08-11
US62/035,857 2014-08-11
PCT/US2014/056401 WO2015084458A2 (en) 2013-09-18 2014-09-18 System and method for movement and timing control

Publications (1)

Publication Number Publication Date
KR20160090284A true KR20160090284A (ko) 2016-07-29

Family

ID=53274255

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020167009683A KR20160090284A (ko) 2013-09-18 2014-09-18 이동 및 타이밍 제어를 위한 시스템 및 방법

Country Status (12)

Country Link
US (1) US10207269B2 (ja)
EP (1) EP3046663A4 (ja)
JP (1) JP2016532075A (ja)
KR (1) KR20160090284A (ja)
CN (1) CN105939779A (ja)
AU (1) AU2014357716A1 (ja)
BR (1) BR112016006025A2 (ja)
CA (1) CA2924522A1 (ja)
HK (1) HK1226023A1 (ja)
IL (1) IL244678A0 (ja)
SG (1) SG11201602064SA (ja)
WO (1) WO2015084458A2 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111727011A (zh) * 2017-11-13 2020-09-29 印度科学院 临床样品存储盒
WO2024048834A1 (ko) * 2022-08-29 2024-03-07 옴니시스템 주식회사 분자 진단용 카트리지
WO2024048835A1 (ko) * 2022-08-29 2024-03-07 옴니시스템 주식회사 분자 진단용 카트리지

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201014805D0 (en) 2010-09-07 2010-10-20 Multi Sense Technologies Ltd Microfluidics based assay device
GB201403790D0 (en) * 2014-03-04 2014-04-16 Ge Healthcare Ltd Microfluidic devices and arrangements for introducing reagents and biological samples to such devices
KR20180040511A (ko) 2014-11-05 2018-04-20 캘리포니아 인스티튜트 오브 테크놀로지 유기체의 약물에 대한 반응의 미세유체 측정
WO2016074046A1 (en) 2014-11-14 2016-05-19 Axxin Pty Ltd Biological sample collection and storage assembly
US10064513B2 (en) * 2015-03-12 2018-09-04 BSH Hausgeräte GmbH Mixed beverage unit
DE102015007642A1 (de) * 2015-06-17 2016-12-22 Sarstedt Ag & Co. Verfahren und Vorrichtung zum Bereitstellen von eine getrocknete Flüssigkeitsmenge, insbesondere Blut, aufweisenden, saugfähigen Probenträgern
AU2016295422B2 (en) * 2015-07-17 2022-01-06 Axxin Pty Ltd Diagnostic test assembly, apparatus, method
JP6619577B2 (ja) * 2015-08-05 2019-12-11 アルプスアルパイン株式会社 流路構造体、測定ユニット、測定対象液体の測定方法、および測定対象液体の測定装置
CN105135051B (zh) * 2015-09-30 2019-06-18 博奥生物集团有限公司 一种微流控阀门和微流控芯片
JP6714986B2 (ja) * 2015-10-05 2020-07-01 株式会社タカゾノテクノロジー シリンジ駆動装置
JP6940890B2 (ja) * 2015-10-05 2021-09-29 株式会社タカゾノテクノロジー 微生物検出装置
JP6653547B2 (ja) * 2015-10-05 2020-02-26 株式会社タカゾノテクノロジー 流体観察装置
WO2017078630A1 (en) * 2015-11-04 2017-05-11 Nitto Denko Corporation Apparatus and system for biofluid sample dispensing and/or assay
EP3353523A4 (en) 2016-02-27 2019-07-03 Hewlett-Packard Development Company, L.P. SAMPLE PREPARATION SYSTEM
JP6765826B2 (ja) * 2016-03-10 2020-10-07 シスメックス株式会社 検体処理方法、検体処理チップおよび検体処理装置
GB201611442D0 (en) * 2016-06-30 2016-08-17 Lumiradx Tech Ltd Fluid control
US20190160466A1 (en) * 2016-08-03 2019-05-30 Kabushiki Kaisha Dnaform Analysis cell, analysis device, analysis apparatus, and analysis system
WO2018058078A1 (en) 2016-09-23 2018-03-29 California Institute Of Technology Digital quantification of dna replication and/or chromosome segregation based determination of antimicrobial susceptibility
US10707531B1 (en) 2016-09-27 2020-07-07 New Dominion Enterprises Inc. All-inorganic solvents for electrolytes
DE102016122056B4 (de) 2016-11-16 2021-02-18 Microfluidic Chipshop Gmbh Mikrofluidisches System zur Aufnahme, Abgabe und Bewegung von Fluiden
CA3045457A1 (en) * 2016-12-01 2018-06-07 Novel Microdevices, Llc Automated point-of-care devices for complex sample processing and methods of use thereof
US11148140B2 (en) * 2017-01-13 2021-10-19 Brandeis University Devices for simultaneous generation and storage of isolated droplets, and methods of making and using the same
EP3554991A4 (en) 2017-02-15 2019-11-27 Hewlett-Packard Development Company, L.P. MICROFLUIDIC NETWORK
DE102017111529A1 (de) * 2017-05-26 2018-11-29 HELLA GmbH & Co. KGaA Sensor für ein Kraftfahrzeug
WO2018221576A1 (ja) * 2017-05-30 2018-12-06 積水化学工業株式会社 マイクロ流体デバイス及びマイクロ流体デバイスシステム
US10572011B2 (en) * 2017-06-30 2020-02-25 Microsoft Technology Licensing, Llc Haptic feedback system
KR102651024B1 (ko) 2017-09-27 2024-03-26 액신 피티와이 엘티디 진단 테스트 시스템 및 방법
EP3692366B1 (en) 2017-10-06 2022-12-14 The Research Foundation for The State University of New York Selective optical aqueous and non-aqueous detection of free sulfites
EP3695009A4 (en) 2017-10-11 2021-08-11 California Institute of Technology ANTIBIOTIC SENSITIVITY OF MICROORGANISMS AND RELATED COMPOSITIONS, PROCEDURES AND SYSTEMS
EP3787792A1 (en) * 2018-05-01 2021-03-10 Precision Planting LLC Analytical cartridge for testing and related methods
DE102018111834A1 (de) * 2018-05-16 2019-11-21 Mildendo Gesellschaft für mikrofluidische Systeme mbH Mikrofluidische Vorrichtung und Verfahren zur Nutzung derselben zur Trennung, Aufreinigung und Konzentration von Komponenten von fluidischen Medien,
WO2020028559A1 (en) * 2018-07-31 2020-02-06 University Of Florida Research Foundation Apparatus and method for performing microorganism detection
US11863041B2 (en) * 2018-08-02 2024-01-02 University Of Massachusetts Devices and methods for clearing and molecular labeling of intact tissues
JP7066043B2 (ja) * 2018-09-11 2022-05-12 エフ.ホフマン-ラ ロシュ アーゲー 液体パックを備えたカートリッジ
US10345758B2 (en) * 2018-10-07 2019-07-09 Rising Star Pathway, a California Corporation Processor controlled energy harvester based on oscillating weight type energy collectors
EP3972655A4 (en) * 2019-05-22 2022-07-06 The Regents of University of California AUTOMATIC ULTRA-COMPACT MICRODROP RADIOSYNTHESIZER
CN110286015A (zh) * 2019-06-28 2019-09-27 江苏中利集团股份有限公司 一种耐热冲击试验制样仪
EP3808453A1 (en) 2019-10-18 2021-04-21 Biothink Technologies S.L. Lab-on-a-chip with electronically-controlled mechanical fluid driving system
WO2021124713A1 (ja) * 2019-12-18 2021-06-24 国立大学法人東北大学 粘度計及び粘度測定方法
EP4110524A4 (en) * 2020-02-27 2024-04-03 One Biomed Pte Ltd DEVICE, SYSTEM AND METHOD FOR ISOLATING A BIOLOGICAL MATERIAL
CN111205966B (zh) 2020-04-18 2020-07-21 博奥生物集团有限公司 样本提取芯片和生物反应装置
CN111218395B (zh) * 2020-04-18 2020-08-07 博奥生物集团有限公司 一种全流程生物检测装置
WO2021221659A1 (en) * 2020-04-30 2021-11-04 Hewlett-Packard Development Company, L.P. Fabrication of multi-layer microfluidic systems
CN111659444A (zh) * 2020-06-20 2020-09-15 珠海复旦创新研究院 一种碳基限域界面负载钯单原子催化剂及其制备方法
MX2023002147A (es) * 2020-08-26 2023-05-04 Sense Biodetection Ltd Dispositivos.
EP4214506A1 (en) * 2020-09-15 2023-07-26 3M Innovative Properties Company Nanopatterned films with patterned surface chemistry
JP7432295B2 (ja) * 2020-12-05 2024-02-16 アジアメディカルセンター,プライベート リミテッド 生体試料処理システム、押圧装置および押圧機構
WO2022125077A1 (en) * 2020-12-08 2022-06-16 Hp Health Solutions Inc. Sample preparation cartridge module
DE102020215981A1 (de) 2020-12-16 2022-06-23 Robert Bosch Gesellschaft mit beschränkter Haftung Prozessierungseinheit, Analysekartusche mit Prozessierungseinheit, Verfahren zum Herstellen einer Prozessierungseinheit und Verfahren zum Herstellen einer Analysekartusche
KR20230169935A (ko) * 2021-01-12 2023-12-18 데피니티브 바이오테크놀로지스 엘엘씨 생물학적 시료들에서 핵산을 검출하기 위한 디바이스및 방법
CN112547139B (zh) * 2021-02-24 2021-07-23 赛默飞世尔(上海)仪器有限公司 用于生物安全柜的反馈机构
CN214654977U (zh) * 2021-04-08 2021-11-09 埃妥生物科技(杭州)有限公司 一种样本反应结构
TWI785636B (zh) 2021-06-07 2022-12-01 新加坡商克雷多生醫有限公司 檢測卡匣
US11779518B2 (en) 2021-08-09 2023-10-10 Express Scripts Strategic Development, Inc. Blister pack device and method
US11857965B2 (en) 2021-08-25 2024-01-02 Hewlett-Packard Development Company, L.P. Microfluidic valves
CN117881479A (zh) * 2021-09-06 2024-04-12 贝克顿·迪金森公司 带有内部柱体和柱塞的诊断测试装置
KR20240052869A (ko) * 2021-09-10 2024-04-23 엘레파스 바이오사이언스 코퍼레이션 조직 절단 시스템 및 방법
GB202118921D0 (en) * 2021-12-23 2022-02-09 Osler Diagnostics Ltd Liquid handling device
CN114486639B (zh) * 2022-04-07 2022-06-14 中国科学院地质与地球物理研究所 基于多液珠接触角测量校正的岩石润湿性测定方法及系统
WO2023247569A1 (en) * 2022-06-20 2023-12-28 Testmate Health Sa Method for dna or rna amplification from urine, saliva and/or mouthwash samples
WO2024040428A1 (zh) * 2022-08-23 2024-02-29 北京京东方技术开发有限公司 检测装置和核酸提取方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4266681A (en) 1977-02-28 1981-05-12 Oceanography International Corporation Multiple breakpoint resealable ampoule
US5947167A (en) * 1992-05-11 1999-09-07 Cytologix Corporation Dispensing assembly with interchangeable cartridge pumps
US5804141A (en) * 1996-10-15 1998-09-08 Chianese; David Reagent strip slide treating apparatus
US6319476B1 (en) 1999-03-02 2001-11-20 Perseptive Biosystems, Inc. Microfluidic connector
JP3823053B2 (ja) * 1999-08-06 2006-09-20 サーモ エレクトロン コーポレイション−ポイント オブ ケア エンド ラピッド ダイアグノスティックス 完全サンプル処理能力を備える、医療現場用検出自動化装置
GB0110476D0 (en) * 2001-04-30 2001-06-20 Secr Defence Reagent delivery system
US7056475B2 (en) 2002-01-30 2006-06-06 Agilent Technologies, Inc. Fluidically isolated pumping and metered fluid delivery system and methods
FR2843048B1 (fr) 2002-08-01 2004-09-24 Commissariat Energie Atomique Dispositif d'injection et de melange de micro-gouttes liquides.
US7122153B2 (en) 2003-01-08 2006-10-17 Ho Winston Z Self-contained microfluidic biochip and apparatus
GB0420878D0 (en) * 2004-09-20 2004-10-20 Randox Lab Ltd Reagent holder and testing assembly incorporating a reagent holder
US7158159B2 (en) 2004-12-02 2007-01-02 Agilent Technologies, Inc. Micro-machined nozzles
WO2007011867A2 (en) * 2005-07-15 2007-01-25 Applera Corporation Fluid processing device and method
TW200714898A (en) * 2005-08-02 2007-04-16 3M Innovative Properties Co Apparatus and method for detecting an analyte
US7951109B2 (en) * 2006-09-22 2011-05-31 Andeboh Holdings, Flp Liquid chamber cap with compartment for use with injectables
EP2109666A4 (en) 2007-02-05 2011-09-14 Integenx Inc MICROFLUIDIC AND NANOFLUIDIC DEVICES, SYSTEMS, AND APPLICATIONS
WO2008112653A1 (en) 2007-03-09 2008-09-18 Dxtech, Llc Electrochemical detection system
US8182769B2 (en) 2008-04-04 2012-05-22 Biomet Biologics, Llc Clean transportation system
EP2280751B1 (en) 2008-05-14 2021-12-01 Biolyph, Llc Reagent mixture preparation and dispensing devices and methods for the same
EP2300164B1 (en) * 2008-06-19 2018-03-14 Boehringer Ingelheim Microparts GmbH Fluid metering container
US20120107811A1 (en) 2009-02-06 2012-05-03 Kelso David M Burstable liquid packaging and uses thereof
US9415392B2 (en) 2009-03-24 2016-08-16 The University Of Chicago Slip chip device and methods
US9260475B2 (en) 2009-06-26 2016-02-16 Claremont Biosolutions Llc Capture and elution of bio-analytes via beads that are used to disrupt specimens
US20110244466A1 (en) 2010-04-02 2011-10-06 Robert Juncosa Nucleic acid testing device and method
DE102011004125A1 (de) 2011-02-15 2012-08-16 Robert Bosch Gmbh Vorrichtung zur hermetisch abgeschlossenen Bevorratung von Flüssigkeiten für ein mikrofluidisches System
EP2633911B1 (en) 2012-02-28 2016-09-14 ARKRAY, Inc. Mixing apparatus
WO2013159116A1 (en) 2012-04-20 2013-10-24 University Of Chicago Fluidic devices for biospecimen preservation
CA2870999A1 (en) 2012-04-20 2013-10-24 SlipChip, LLC Fluidic devices and systems for sample preparation or autonomous analysis
US20130331298A1 (en) 2012-06-06 2013-12-12 Great Basin Scientific Analyzer and disposable cartridge for molecular in vitro diagnostics

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111727011A (zh) * 2017-11-13 2020-09-29 印度科学院 临床样品存储盒
WO2024048834A1 (ko) * 2022-08-29 2024-03-07 옴니시스템 주식회사 분자 진단용 카트리지
WO2024048835A1 (ko) * 2022-08-29 2024-03-07 옴니시스템 주식회사 분자 진단용 카트리지

Also Published As

Publication number Publication date
JP2016532075A (ja) 2016-10-13
WO2015084458A3 (en) 2015-09-03
CA2924522A1 (en) 2015-06-11
HK1226023A1 (zh) 2017-09-22
IL244678A0 (en) 2016-04-21
EP3046663A2 (en) 2016-07-27
SG11201602064SA (en) 2016-04-28
EP3046663A4 (en) 2017-05-31
BR112016006025A2 (pt) 2017-08-01
US10207269B2 (en) 2019-02-19
US20160263577A1 (en) 2016-09-15
CN105939779A (zh) 2016-09-14
WO2015084458A2 (en) 2015-06-11
AU2014357716A1 (en) 2016-04-07

Similar Documents

Publication Publication Date Title
US10207269B2 (en) System and method for movement and timing control
AU2016204953B2 (en) Fluidic devices and systems for sample preparation or autonomous analysis
US9808798B2 (en) Fluidic devices for biospecimen preservation
US9803237B2 (en) Slip-induced compartmentalization
Kong et al. Lab-on-a-CD: A fully integrated molecular diagnostic system
EP3102329B1 (en) Sample preparation module with stepwise pressurization mechanism
US8642293B2 (en) Disposable device for analyzing a liquid sample containing a nucleic acid with a nucleic acid amplification apparatus
CA2756463C (en) Slip chip device and methods
KR102027441B1 (ko) 샘플 투입 및 결과 발생 처리를 제공하기 위한 단일한 바이오칩 및 이의 제조 방법
US20190111423A1 (en) Devices and methods for autonomous measurements
US20120230887A1 (en) Devices and methods for interfacing microfluidic devices with macrofluidic devices
AU2017202597B2 (en) Slip chip device and methods
Laurell et al. Lab on a chip: Scandinavia

Legal Events

Date Code Title Description
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid