KR20160050126A - Toothpaste Composition for Whitening Tooth Using Scoria Powder - Google Patents

Abstract

Disclosed in the present invention is a toothpaste composition using a scoria powder. Specifically, disclosed is a toothpaste composition for teeth whitening, comprising a scoria powder having a teeth whitening effect as a polishing agent, thereby having a teeth whitening effect.

Description

{Toothpaste Composition for Whitening Tooth Using Scoria Powder}

The present invention relates to a dentifrice composition using a volcanic stone scoria powder.

In general, the coloring factors of teeth are classified into extrinsic and intrinsic staining. Exogenous staining occurs when food waste, tobacco, coffee, tea, sugar, etc. are deposited on the surface of the teeth. It is known that tetracyclines are caused by excessive use of antibiotics, aging, and the like.

The tooth whitening agent is divided into an abrasive that physically removes the foreign coloring, a coloring matter dissolving agent that chemically removes the foreign coloring material, and a peroxide that removes the endogenous coloring by releasing active oxygen.

The abrasive agent is physically used to polish the surface of a tooth to smooth the surface to show a whitening effect. Normally, calcium carbonate, precipitated silica, silica gel, zirconium silicate, calcium monohydrogenphosphate, aluminum silicate and the like are usually used. Limonene, citric acid, malic acid, malic acid, tartaric acid, glycolic acid, glutaric acid, and the like are commonly used to exhibit a whitening effect by corroding. However, the abrasive may cause tooth cervical abrasion and the coloring matter dissolving agent may cause irritable teeth.

Although peroxide can be expected to have a whitening effect of endogenous coloring, safety of the human body is controversial when it is used in an excessive amount, compatibility with general components of toothpaste is not good, peroxide itself is very unstable, There is a problem that it rapidly decreases.

Conventional toothpastes are mixed with each other because of the limited effects and disadvantages of these tooth whitening agents.

The present invention discloses a dentifrice composition capable of exhibiting a tooth whitening effect by using a volcanic stone clay as an abrasive.

It is an object of the present invention to provide a dentifrice composition using a volcanic stone clay.

Other and further objects of the present invention will be described below.

As shown in the following Examples and Experimental Examples, the inventors of the present invention found that when a dentifrice composition containing 10% by weight to 40% by weight of clove powder was prepared as an abrasive and the tooth whitening effect was confirmed through clinical evaluation, It was confirmed that the tooth whitening effect was improved in proportion.

When the antimicrobial activity of Prevotella intermedia , one of the causative microorganisms of gingivitis, was measured by the disk diffusion method, the present inventors measured the effects of the extracts of the beech mung bean moth, The extracts showed antimicrobial activity.

The dentifrice composition of the present invention is provided on the basis of the results of such experiments. The dentifrice composition of the present invention is a dentifrice composition containing a volcanic stone meal powder having a tooth whitening effect as an abrasive and having an antibacterial activity against preboter intermedia, Characterized in that it contains an extract.

As used herein, "scoria" refers to a porous basaltic rock mass having a pore volume and a solid volume similar to that of volcanic ash (less than 2 mm), volcanic gravel (volcanic ash, lapilli, 2 ~ 64mm), volcanic blocks (more than 64mm), and volcanic bombs. Pine mushroom can be found in the topography formed by the volcano. In Korea, it is easily found in the volcanic island of Jeju Island. Jeju pine mushroom has a variety of colors depending on its major constituents. The cluster with a high content of silicon oxide has a dark gray color, the cluster with high oxidized aluminum content has a yellowish brown or black color, and the cluster with a high content of titanium oxide and iron oxide has a reddish brown color. It is known that Jeju mushroom usually has a melting point of 1,120 ~ 1210 ℃, a water uptake of 17.7 ~ 32.5% and a wear rate of 47.25 ~ 67.22%. The cluster that can be used in the present invention is not particularly limited to the Jeju cluster, but it is preferable that the cluster is Jeju cluster which is known to have excellent functionality such as far infrared radiation, heavy metal adsorption effect, deodorization effect and antibacterial effect.

In the present specification, the term "extract" means an extract obtained by immersing the dumpling bead moth outpost or the mothodiforme moth outpost, which is the object to be extracted, in an aqueous ethanol solution (mixed solvent of ethanol and water). Any extraction method such as cold beating, refluxing, heating, ultrasonic irradiation, etc. can be applied to the extraction method as long as it is obtained by immersing the beeswax seeds outward or the outwardly drawn out wasteweed outflow into ethanol aqueous solution.

In the dentifrice composition of the present invention, the grain powder is contained as an abrasive, but a known abrasive may be further contained together with the grain powder. Examples of such abrasive include calcium carbonate, precipitated silica, silica gel, aluminum hydroxide, calcium monohydrogenphosphate, insoluble sodium metaphosphate, zirconium silicate, anhydrous calcium hydrogenphosphate, hydrated alumina, light calcium carbonate, heavy calcium carbonate, calcium pyrophosphate, Phosphate, aluminum silicate and the like. The powdery mulberry powder may be used alone or in admixture with one or more of these abrasives, in an amount of 1 to 60 wt%, preferably 10 to 50 wt%, based on the total weight (100 wt%) of the dentifrice composition of the present invention % Of the dentifrice composition of the present invention. More preferably 10 to 30% by weight so as to minimize the side effect of tooth wear while sufficiently exhibiting the effect as an abrasive, as confirmed in the following experimental examples.

The grain size suitable for use as the abrasive powder can be determined within a range of ordinary skill in the art, but it is preferably not more than 30 占 퐉, more preferably not more than 20 占 퐉 in order to make the sandy- . The gypsum powder can be obtained by any method known in the art such as a dry grinding method and a wet grinding method, and is preferably obtained by a dry grinding method. Since the powder produced by the dry pulverization method contains water generally below 1% (v / v), when the particles of the powder are not agglomerated and dispersed in the aqueous medium, the re-agglomeration phenomenon of the particles rarely occurs It is not.

The dentifrice composition of the present invention contains a coloring matter dissolving agent, a peroxide, a wetting agent, a foaming agent, a binder, a sweetener, a preservative, a medicinal ingredient, a fragrance, a brightener, a pigment, a solvent and the like commonly used for toothpaste .

The colorant solubilizer is a component for chemically dissolving and removing the hydrophobic coloring material adhered to the tooth surface, and may be a mixture of at least one selected from the group consisting of limonene, citric acid, malic acid, malic acid, glycolic acid tartaric acid and glutaric acid .

The coloring material dissolving agent may be contained in an amount of 0.1 to 1.0% by weight based on the total weight of the dentifrice composition of the present invention. If the content is less than 0.1% by weight, the solubility of the coloring material may be too low. If the content is more than 1.0% by weight, flavor peculiar to the dissolvent may be felt, which is undesirable. have.

The peroxide is used for whitening to endogenous tooth coloration, and may be hydrogen peroxide, hydrogen peroxide, sodium peroxide, calcium peroxide, or a mixture of two or more thereof. Such peroxides may be used in an amount of 0.5 to 10% by weight based on the total weight of the dentifrice composition. If it is used in an amount of less than 0.5% by weight, it is difficult to expect a tooth whitening effect. If it is used in an amount of more than 10% by weight, side effects may occur on the gums.

When hydrogen peroxide is used as a peroxide, hydrogen peroxide has a strong acidity in the range of pH 1.8 to 3.5. Therefore, hydrogen peroxide decomposes to water and hydrogen in the basic condition and is not stable. Therefore, ultrapure condensation phosphate, polyvinylpyrrolidone, polyacrylic acid, It is preferable to use a stabilizer such as an alkyl carboxylate salt or the like.

The wetting agent is intended to prevent the toothpaste from drying and solidifying when the toothpaste is exposed to air. The wetting agent imparts gloss to the surface of the toothpaste and may exhibit a sweetening effect depending on the type of toothpaste. Examples of the wetting agent include glycerin, sorbitol, xylitol, polyethylene glycols, propylene glycol, and mixtures of two or more thereof. The wetting agent may be used in an amount of 10 to 40% by weight based on the total weight of the dentifrice composition.

The foaming agent is a component used for the purpose of improving the feeling of use of the product, helping the cleaning action, accelerating the dispersion and penetration of other active ingredients, and reducing the interfacial tension so that the foreign substances in the mouth easily fall off. Examples of the foaming agent include nonionic surfactants such as polyoxyethylene sorbitan fatty acid esters, polyoxyethylene (hardened) castor oil, glycerin fatty acid esters, sorbitan fatty acid esters, sucrose fatty acid esters, alkylolamides and alkyl glucosides, And anionic surfactants such as sodium lauryl sulfate may be used, and it may be used in an amount of 0.5 to 5.0% by weight based on the total weight of the dentifrice composition.

The binder is used for the purpose of not separating the liquid component from the solid component of the powdered tooth powder. Any binder may be used as long as it is a water-soluble polymer. Examples of the binder include carboxymethyl cellulose sodium, hydroxyethyl cellulose, hydroxypropyl cellulose, carrageenan, xanthan gum, sodium alginate, and mixtures of two or more thereof. May be used in an amount of 0.1 to 5% by weight based on the total weight of the dentifrice composition.

The sweetener is used for the purpose of improving the sensation of use. Examples of the sweetener include saccharin sodium, aspartame, stevioside, xylitol, licorice acid, and mixtures of two or more thereof. The sweetener is used in an amount of 0.05 to 5% Can be used.

The active ingredient is used for the purpose of prevention of cavities and periodontitis, suppression of plaque and the like. Examples thereof include sodium fluoride, sodium fluoride, fluoride, tin fluoride, sodium fluoride, chlorhexidine, allantoin chlorohydroxy aluminate, amino Caproic acid, triclosan chloride, cetylpyridinium chloride, zinc chloride, pyridoxine hydrochloride, tocopherol acetate, sodium hydrogencarbonate, aminocaproic acid, allantoin, allantoin derivatives, vitamins and the like. Such active ingredient may be used in an amount of 0.1 to 5% by weight based on the total weight of the dentifrice composition.

As the preservative, p-hydroxybenzoic acid methyl ester, p-hydroxybenzoic acid propyl ester, sodium benzoate and the like can be used. As the flavor, peppermint oil, spearmint oil, menthol, anethole and the like can be used. These preservatives and fragrances may be added in an appropriate amount (0.01 to 2.0% by weight) to suit the purpose to which they are added.

In addition, titanium oxide or the like may be used as the brightening agent, an edible pigment as the coloring matter, and purified water or ethanol as the solvent.

Formulations of the dentifrice compositions of the present invention will normally be prepared in ointment (i.e., paste) and filled into tubes for use.

INDUSTRIAL APPLICABILITY As described above, according to the present invention, it is possible to provide a dentifrice composition for dentifrice whitening using a cluster powder as an abrasive.

In addition to the tooth whitening effect, the use of the pine needle powder as an abrasive agent can also exhibit the effects of inhibiting and preventing bad breath due to the antimicrobial effect and deodorizing effect of the pine clusters.

Hereinafter, the present invention will be described with reference to Examples and Experimental Examples. However, the scope of the present invention is not limited to these examples and experimental examples.

< Example  1> Preparation of dentifrice composition using pine needle powder

<1> Production of cluster powder

The clustered clusters of reddish brown patches were collected and collected into a clustered powder having an average particle size of 10 탆 by using a dry grinder, supercritical carbon dioxide was added to the clustered powder at a temperature of 100 캜 and a pressure of 600 bar, And microorganisms were removed.

&Lt; 2 > Preparation Example of dentifrice composition and comparative preparation example

The ingredients and the contents of [Table 1] below were stirred for 20 minutes in a vacuum to prepare a dentifrice composition.

Composition and content of dentifrice composition division Production Example 1 Production Example 2 Production Example 3 Production Example 4 glycerin 20 20 20 20 Carrageenan 1.5 1.5 1.5 1.5 Sodium lauryl sulfate 2.5 2.5 2.5 2.5 Sodium saccharin 0.2 0.2 0.2 0.2 Citric acid 0.1 0.1 0.1 0.1 Malian 0.1 0.1 0.1 0.1 Clay powder 10 20 30 40 antiseptic 0.05 0.05 0.05 0.05 Beauty 1.0 1.0 1.0 1.0 Purified water To 100 To 100 To 100 To 100

In Table 1, glycerin was used as the wetting agent, carrageenan was used as the binder, sodium lauryl sulfate was used as the base agent, and saccharin sodium was used as the sweetener. Citric acid and malic acid were used as the colorant dissolving agents. And preservatives and fragrances were used as trace amounts.

< Example  2> Dumpling beads  The preparation of the extract and Zanthoxine  Preparation of extract

Four times the weight of 70% ethanol was added to each of these dried powders for 24 hours at room temperature, followed by filtration through Wattman filter paper 2 and concentration under reduced pressure.

< Experimental Example  1> Teeth whitening effect experiment

A gel-like mixture obtained by uniformly mixing a cigarette, coffee, tea powder and sugar which may cause external coloring of the teeth is placed in a container equipped with a rotating plate, and then a tooth specimen obtained from a healthy person of 10 to 20 years After the rotation plate was fixed, the rotation plate was rotated for 72 hours to induce coloring of the tooth sample. Thereafter, the color-induced tooth specimens were dried on a shade for 2 days, and then applied to a toothbrush fixed on the axis of motion so that reciprocating motion can be performed 90 times per minute using the dentifrice compositions of the preparation examples and the comparative examples. The specimens were artificially ground for 20 minutes. The whiteness degree was measured using a colorimeter (SZ, Nippon Denshoku) before and after the artificial polishing, and the degree of increase (? L) of the whiteness before and after polishing was shown in Table 2.

The degree of increase (? L) division The degree of increase (? L) Production Example 1 28.7 Production Example 2 42.5 Production Example 3 54.3 Production Example 4 67.6

Referring to Table 2, it can be seen that whiteness is increased in proportion to the content of the volcanic stone powder.

< Experimental Example  2> Experimental evaluation of tooth polishing

40 participants from 30 to 40 were divided into 4 groups of 10 persons each. The dentifrice composition of Table 3 was used three times a day for 3 days, and the degree of abrasive force after use was measured by the following five point scale method .

5 points: Very strong.

4 points: It is strong.

3 points: It is normal.

2 points: weak

1 point: Very weak.

Sensory Evaluation Results on Grinding Force division Grinding force evaluation result Production Example 1 2.8 Production Example 2 3.2 Production Example 3 3.5 Production Example 4 4.6

Referring to the results of Table 3 above, it was found that the polishing force was increased in proportion to the amount of the clathrate powder used. In particular, when the clathrate powder was used in an amount of 40% by weight (Production Example 4) Was evaluated as falling. It is preferable to use 10% by weight to 30% by weight in the case where the germinated powder is included in the dentifrice composition as evaluated in the case of using the lowest 10% by weight of the germanium powder (Preparation Example 1) .

< Experimental Example  3> Gingivitis causing bacteria Prevotella Intermedia Antibacterial activity test

ATCC 25611 from ATCC (American Type Culture Collection, USA ) was used as a prebacterial strain, and Bactron IV Chamber (SHELLAB, USA), an anaerobic chamber maintained at 37 ° C, contained Tryptic Soy Agar TSA, Difco Laboratories, USA) under anaerobic conditions of 5% CO ₂ , 10% H ₂ , and 85% N ₂ .

The antimicrobial activity was measured using a disc diffusion assay. Specifically, each sample of the above example was prepared at a concentration of 1 mg / ml, slowly absorbed in a paper disc (Whatman No. 5, 8 mm) It was completely evaporated. Then, the paper disc was placed on a Tryptic Soy Agar plate medium coated with Prevotella intermedia and incubated at 37 ° C for 48 hours under anaerobic conditions to determine the size of the clear zone (mm) And the antibacterial activity was evaluated.

All experiments were carried out three times and the results are shown in Table 4 below as the mean value and the standard deviation.

Results of antibacterial activity division clear zone (mm) Dumpling bead moth extract 3.6 ± 0.2 Zanthoxylum cepa extract 3.1 ± 0.1

The results of the above Table 4 show that the antimicrobial activity against the preboter intermedia, which is a causative organism of gingivitis, is exhibited in both the mulberry mugwort mugwort extract and the mugwort mugwort mugwort extract. Especially, the antimicrobial activity of the mugwort mugwort mugwort extract is high.

Claims (4)

And a volcanic stone scoria powder having a tooth whitening effect as an abrasive,
A dentifrice composition comprising a dumpling bean moth extract or a mung bean moth moth extract having antimicrobial activity against Prebotella intermedia, a causative agent of gingivitis.
The method according to claim 1,
Wherein the dentifrice composition further comprises at least one selected from the group consisting of a coloring matter dissolving agent, a peroxide, a wetting agent, a foaming agent, a binder, a sweetener, a preservative, a medicinal ingredient, a fragrance, a brightener, a pigment and a solvent.
The method according to claim 1,
Wherein the volcanic stone powder has an average particle size of 30 탆 or less and is contained in an amount of 1 to 60% by weight based on the total weight of the dentifrice composition.
The method according to claim 1,
Wherein the extract is obtained by extracting with a mixed solvent of water and ethanol.