KR20160011625A - 새로운 α4β7 펩타이드 이량체 길항제들 - Google Patents
새로운 α4β7 펩타이드 이량체 길항제들 Download PDFInfo
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- KR20160011625A KR20160011625A KR1020157031177A KR20157031177A KR20160011625A KR 20160011625 A KR20160011625 A KR 20160011625A KR 1020157031177 A KR1020157031177 A KR 1020157031177A KR 20157031177 A KR20157031177 A KR 20157031177A KR 20160011625 A KR20160011625 A KR 20160011625A
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US201361807714P | 2013-04-02 | 2013-04-02 | |
| US61/807,714 | 2013-04-02 | ||
| US14/229,784 | 2014-03-28 | ||
| US14/229,784 US20140294901A1 (en) | 2013-04-02 | 2014-03-28 | Novel a4b7 peptide dimer antagonists |
| PCT/US2014/032391 WO2014165448A1 (en) | 2013-04-02 | 2014-03-31 | NOVEL α4β7 PEPTIDE DIMER ANTAGONISTS |
Publications (1)
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| KR20160011625A true KR20160011625A (ko) | 2016-02-01 |
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| EP (1) | EP2981544B1 (https=) |
| JP (1) | JP6499157B2 (https=) |
| KR (1) | KR20160011625A (https=) |
| CN (1) | CN105339383A (https=) |
| AU (2) | AU2014248321A1 (https=) |
| CA (1) | CA2908593A1 (https=) |
| HK (1) | HK1221233A1 (https=) |
| SG (2) | SG10201708103RA (https=) |
| WO (1) | WO2014165448A1 (https=) |
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| US9273093B2 (en) | 2012-10-11 | 2016-03-01 | Protagonist Therapeutics, Inc. | α4β7 peptide dimer antagonists |
| EP4091624A1 (en) | 2013-03-15 | 2022-11-23 | Protagonist Therapeutics, Inc. | Hepcidin analogues and uses thereof |
| HRP20211448T1 (hr) | 2014-05-16 | 2021-12-24 | Protagonist Therapeutics, Inc. | Alfa4beta7 integrin tioeter peptidni antagonisti |
| CN107206254B (zh) | 2014-07-17 | 2021-08-24 | 领导医疗有限公司 | 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途 |
| US10301371B2 (en) | 2014-10-01 | 2019-05-28 | Protagonist Therapeutics, Inc. | Cyclic monomer and dimer peptides having integrin antagonist activity |
| WO2016054411A1 (en) | 2014-10-01 | 2016-04-07 | Protagonist Therapeutics, Inc. | NOVEL α4β7 PEPTIDE MONOMER AND DIMER ANTAGONISTS |
| US10787490B2 (en) | 2015-07-15 | 2020-09-29 | Protaganist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| KR20180100302A (ko) * | 2015-10-23 | 2018-09-10 | 우니베르지태트 트벤테 | 인테그린 결합 펩티드 및 그의 용도 |
| US20190002503A1 (en) | 2015-12-30 | 2019-01-03 | Protagonist Therapeutics, Inc. | Analogues of hepcidin mimetics with improved in vivo half lives |
| CA3017926C (en) * | 2016-03-23 | 2023-10-10 | Protagonist Therapeutics, Inc. | Methods for synthesizing .alpha.4.beta.7 peptide antagonists |
| EP3681900A4 (en) | 2017-09-11 | 2021-09-08 | Protagonist Therapeutics, Inc. | OPIOID AGONIST PEPTIDES AND THEIR USES |
| CA3089868A1 (en) | 2018-02-08 | 2019-08-15 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
| WO2020014646A1 (en) | 2018-07-12 | 2020-01-16 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| JP7534382B2 (ja) | 2019-07-10 | 2024-08-14 | プロタゴニスト セラピューティクス， インコーポレイテッド | インターロイキン－２３受容体のペプチド阻害剤及び炎症性疾患を治療するためのその使用 |
| AU2021209086A1 (en) | 2020-01-15 | 2022-08-04 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| CA3167751A1 (en) | 2020-01-15 | 2021-07-22 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| JP7397239B2 (ja) | 2020-11-20 | 2023-12-12 | ヤンセン ファーマシューティカ エヌ．ベー． | インターロイキン－２３受容体のペプチド阻害剤の組成物 |
| EP4370146A4 (en) | 2021-07-14 | 2025-05-21 | Janssen Biotech, Inc. | Lipidated peptide inhibitors of the interleukin-23 receptor |
| CN114874107B (zh) * | 2022-07-12 | 2022-11-29 | 中山大学附属第七医院(深圳) | 一种氨基脂质及其制备方法和应用 |
Family Cites Families (11)
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| US6037324A (en) * | 1996-01-04 | 2000-03-14 | Leukosite, Inc. | Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor |
| GB9613112D0 (en) * | 1996-06-21 | 1996-08-28 | Zeneca Ltd | Chemical compounds |
| US6818617B1 (en) * | 1997-08-15 | 2004-11-16 | Temple University- Of The Commonwealth System Of Higher Education | EC-3, an inhibitor of α4β1 and α4β7 integrins |
| AU750175B2 (en) * | 1997-11-24 | 2002-07-11 | Merck & Co., Inc. | Cyclic amino acid derivatives as cell adhesion inhibitors |
| KR100983997B1 (ko) * | 2001-01-09 | 2010-09-28 | 메르크 파텐트 게엠베하 | 수용체 타이로신 키나아제 저해제 및 혈관형성 저해제를 사용하는 병용 요법 |
| GB0610395D0 (en) * | 2006-05-25 | 2006-07-05 | Ge Healthcare Ltd | Novel imaging agents |
| US9193790B2 (en) * | 2006-12-07 | 2015-11-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of antagonists of the interaction between HIV GP120 and A4B7 integrin |
| WO2009039185A1 (en) * | 2007-09-17 | 2009-03-26 | The Trustees Of Columbia University In The City Of New York | Uses of immunologically modified scaffold for tissue prevascularization and cell transplantation |
| JP2011231085A (ja) * | 2010-04-30 | 2011-11-17 | Osaka Prefecture Univ | 環状ペプチド |
| EP2444101A1 (en) * | 2010-10-21 | 2012-04-25 | Universitätsklinikum Freiburg | Selective targeting of the CD40L/Mac-1 interaction by small peptide inhibitors and its use for the treatment of inflammation and atherogenesis |
| US9273093B2 (en) * | 2012-10-11 | 2016-03-01 | Protagonist Therapeutics, Inc. | α4β7 peptide dimer antagonists |
-
2014
- 2014-03-28 US US14/229,784 patent/US20140294901A1/en not_active Abandoned
- 2014-03-31 WO PCT/US2014/032391 patent/WO2014165448A1/en not_active Ceased
- 2014-03-31 SG SG10201708103RA patent/SG10201708103RA/en unknown
- 2014-03-31 CN CN201480028920.2A patent/CN105339383A/zh active Pending
- 2014-03-31 HK HK16109329.5A patent/HK1221233A1/zh unknown
- 2014-03-31 EP EP14779463.0A patent/EP2981544B1/en active Active
- 2014-03-31 CA CA2908593A patent/CA2908593A1/en not_active Abandoned
- 2014-03-31 SG SG11201508178UA patent/SG11201508178UA/en unknown
- 2014-03-31 JP JP2016506352A patent/JP6499157B2/ja active Active
- 2014-03-31 KR KR1020157031177A patent/KR20160011625A/ko not_active Withdrawn
- 2014-03-31 AU AU2014248321A patent/AU2014248321A1/en not_active Abandoned
-
2017
- 2017-12-08 US US15/836,648 patent/US20190002500A1/en not_active Abandoned
-
2018
- 2018-08-27 AU AU2018220168A patent/AU2018220168A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20190002500A1 (en) | 2019-01-03 |
| CA2908593A1 (en) | 2014-10-09 |
| JP2016518351A (ja) | 2016-06-23 |
| AU2014248321A1 (en) | 2015-10-29 |
| EP2981544A4 (en) | 2016-12-07 |
| EP2981544B1 (en) | 2019-09-04 |
| SG10201708103RA (en) | 2017-11-29 |
| HK1221233A1 (zh) | 2017-05-26 |
| JP6499157B2 (ja) | 2019-04-10 |
| CN105339383A (zh) | 2016-02-17 |
| WO2014165448A1 (en) | 2014-10-09 |
| AU2018220168A1 (en) | 2018-09-13 |
| SG11201508178UA (en) | 2015-11-27 |
| EP2981544A1 (en) | 2016-02-10 |
| US20140294901A1 (en) | 2014-10-02 |
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