KR20140143361A - 다능성 배엽층 기원 항원 제시 암 백신 - Google Patents

다능성 배엽층 기원 항원 제시 암 백신 Download PDF

Info

Publication number
KR20140143361A
KR20140143361A KR1020147024678A KR20147024678A KR20140143361A KR 20140143361 A KR20140143361 A KR 20140143361A KR 1020147024678 A KR1020147024678 A KR 1020147024678A KR 20147024678 A KR20147024678 A KR 20147024678A KR 20140143361 A KR20140143361 A KR 20140143361A
Authority
KR
South Korea
Prior art keywords
cells
gamma
cancer
ifn
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020147024678A
Other languages
English (en)
Korean (ko)
Inventor
앤드류 콘포스
로버트 딜만
Original Assignee
캘리포니아 스템 셀, 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 캘리포니아 스템 셀, 인코포레이티드 filed Critical 캘리포니아 스템 셀, 인코포레이티드
Publication of KR20140143361A publication Critical patent/KR20140143361A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0639Dendritic cells, e.g. Langherhans cells in the epidermis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/19Dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/20Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24Antigen-presenting cells [APC]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4244Enzymes
    • A61K40/4245Tyrosinase or tyrosinase related proteinases [TRP-1 or TRP-2]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4267Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K40/4268MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4271Melanoma antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4271Melanoma antigens
    • A61K40/4272Melan-A/MART
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/876Skin, melanoma

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
KR1020147024678A 2012-02-02 2013-01-31 다능성 배엽층 기원 항원 제시 암 백신 Ceased KR20140143361A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261594304P 2012-02-02 2012-02-02
US61/594,304 2012-02-02
PCT/US2013/024123 WO2013116505A1 (en) 2012-02-02 2013-01-31 Pluripotent germ layer origin antigen presenting cancer vaccine

Publications (1)

Publication Number Publication Date
KR20140143361A true KR20140143361A (ko) 2014-12-16

Family

ID=48905824

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147024678A Ceased KR20140143361A (ko) 2012-02-02 2013-01-31 다능성 배엽층 기원 항원 제시 암 백신

Country Status (13)

Country Link
US (1) US20150064217A1 (https=)
EP (1) EP2809775B1 (https=)
JP (1) JP2015506698A (https=)
KR (1) KR20140143361A (https=)
CN (1) CN104540937A (https=)
AU (1) AU2013215116A1 (https=)
CA (1) CA2863653A1 (https=)
GB (1) GB2512558A (https=)
HK (2) HK1202432A1 (https=)
IL (1) IL233928A0 (https=)
NZ (1) NZ628292A (https=)
SG (1) SG11201404543UA (https=)
WO (2) WO2013116541A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103599528B (zh) * 2013-12-04 2015-08-05 深圳市合一康生物科技股份有限公司 人树突状细胞疫苗的制备方法
RU2684911C2 (ru) 2014-10-07 2019-04-16 Ситлимик Инк. Пептид, полученный из hsp70, фармацевтическая композиция для лечения или профилактики рака, содержащая такой пептид, индуктор иммунного ответа и способ получения антиген-презентирующей клетки
AU2017342189B2 (en) 2016-10-11 2023-09-21 Nec Corporation Medicine
JPWO2018131659A1 (ja) * 2017-01-11 2019-12-12 国立研究開発法人国立がん研究センター 免疫療法剤
AU2018222737B2 (en) * 2017-02-17 2021-03-25 Aivita Biomedical, Inc. Methods to enhance tumor immunogenicity and compositions for autologous cancer immunotherapeutic products using modified tumor cells and modified dendritic cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL140796A0 (en) * 2001-01-08 2002-02-10 Hadasit Med Res Service An autologous anti-cancer vaccine
CN1636229B (zh) * 2001-09-06 2012-12-19 西北生物治疗药物公司 引发单核树突细胞和t细胞th-1应答的组合物和方法
JP5623004B2 (ja) * 2004-10-25 2014-11-12 ベイラー リサーチ インスティテュートBaylor Research Institute 熱ショックをかけたメラノーマ細胞体が装填された樹状細胞
KR101374091B1 (ko) * 2005-07-29 2014-03-17 프로비던스 헬스 앤드 서비시즈, 오레곤 수포에 담긴 불완전 리보솜 생성물(DRibble) 및 면역 반응을 자극하기 위해 이를 이용하는 방법
WO2008039974A2 (en) * 2006-09-28 2008-04-03 Cedars-Sinai Medical Center Cancer vaccines and vaccination methods
US20090041792A1 (en) * 2007-07-19 2009-02-12 Istituto Superiore Di Sanita Dendritic cells, uses therefor, and vaccines and methods comprising the same

Also Published As

Publication number Publication date
HK1209455A1 (en) 2016-04-01
JP2015506698A (ja) 2015-03-05
IL233928A0 (en) 2014-09-30
EP2809775B1 (en) 2018-06-13
NZ628292A (en) 2016-09-30
HK1202432A1 (en) 2015-10-02
US20150064217A1 (en) 2015-03-05
EP2809775A4 (en) 2015-07-01
CN104540937A (zh) 2015-04-22
CA2863653A1 (en) 2013-08-08
SG11201404543UA (en) 2014-08-28
GB201414403D0 (en) 2014-10-01
GB2512558A (en) 2014-10-01
EP2809775A1 (en) 2014-12-10
AU2013215116A1 (en) 2014-08-21
WO2013116505A1 (en) 2013-08-08
WO2013116541A1 (en) 2013-08-08

Similar Documents

Publication Publication Date Title
US9555058B2 (en) Antigen presenting cancer vaccine
Hipp et al. Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses
Jacobs et al. An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma
AU2023208190B2 (en) Methods relating to activated dendritic cell compositions and immunotherapeutic treatments for subjects with advanced cancers
US20170173079A1 (en) Method of Ex Vivo Enhancement of Immune Cell Activity for Cancer Immunotherapy with a Small Molecule Ablative Compound
EP2809775B1 (en) Pluripotent germ layer origin antigen presenting cancer vaccine
Bot et al. Cancer vaccines
US20170274069A1 (en) Method for the cancer treatment and prevention of metastatic disease
Knudsen et al. Enhanced T‐cell activation by immature dendritic cells loaded with HSP70‐expressing heat‐killed melanoma cells
HK1230080A1 (en) Antigen presenting cancer vaccine with gamma interferon
NZ623917B2 (en) Antigen presenting cancer vaccine
Dahlfrancis In Vitro Effects of the Second-Generation Proteasome Inhibitor Carfilzomib on Human Monocyte-Derived Dendritic Cells
Kerr Development of an autologous dentritic cell vaccine for the treatment of malignant melanoma and high grade gliomas
Cantrell Adjuvant effect of chaperone-rich cell lysate: the effects of CRCL on the activation of immune cells
Biollaz et al. Site-specific anti-tumor immunity: differences in DC function, TGF-β production and numbers of intratumoral Foxp3+ regulatory T cells
Roomi et al. Regulation of MMP-2 and MMP-9 Expression in Childhood Osteosarcoma by Inducers and Inhibitors

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20140902

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
N231 Notification of change of applicant
PN2301 Change of applicant

Patent event date: 20161213

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20171218

Comment text: Request for Examination of Application

N231 Notification of change of applicant
PN2301 Change of applicant

Patent event date: 20180123

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20181220

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20190303

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20181220

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I