KR20140138956A - Ｅ-카드헤린의 세포외 도메인의 저해제를 포함하는 병용 치료법 - Google Patents
Ｅ-카드헤린의 세포외 도메인의 저해제를 포함하는 병용 치료법 Download PDFInfo
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- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261611390P | 2012-03-15 | 2012-03-15 | |
| US61/611,390 | 2012-03-15 | ||
| US201261736475P | 2012-12-12 | 2012-12-12 | |
| US61/736,475 | 2012-12-12 | ||
| PCT/US2013/032656 WO2013138790A1 (en) | 2012-03-15 | 2013-03-15 | Combination therapies including inhibitors of the extracellular domain of e-cadherin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20140138956A true KR20140138956A (ko) | 2014-12-04 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147028934A Withdrawn KR20140138956A (ko) | 2012-03-15 | 2013-03-15 | Ｅ-카드헤린의 세포외 도메인의 저해제를 포함하는 병용 치료법 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20150037354A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2844270A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2015514062A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20140138956A (cg-RX-API-DMAC7.html) |
| CN (1) | CN104519899A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2867456A1 (cg-RX-API-DMAC7.html) |
| RU (1) | RU2014141114A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013138790A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014043633A1 (en) * | 2012-09-17 | 2014-03-20 | Agios Pharmaceuticals, Inc. | Use of e-cadherin and vimentin for selection of treatment responsive patients |
| KR20150085078A (ko) | 2012-11-21 | 2015-07-22 | 아지오스 파마슈티컬스 아이엔씨. | 글루타마제 억제제 및 사용 방법 |
| US9029531B2 (en) | 2012-11-22 | 2015-05-12 | Agios Pharmaceuticals, Inc. | Compounds and their methods of use |
| WO2014079011A1 (en) | 2012-11-22 | 2014-05-30 | Agios Pharmaceuticals, Inc. | Heterocyclic compounds for inhibiting glutaminase and their methods of use |
| CA2943339A1 (en) | 2014-03-21 | 2015-09-24 | Agios Pharmaceuticals, Inc. | Compounds and their methods of use |
| DK3170005T3 (da) * | 2014-07-18 | 2019-07-08 | Sanofi Sa | Fremgangsmåde til forudsigelse af resultatet af en behandling med aflibercept hos en patient, der mistænkes for at lide af cancer |
| CN111208283B (zh) * | 2018-11-21 | 2023-09-26 | 中国科学院分子细胞科学卓越创新中心 | 增效的肿瘤抑制组合物及其应用 |
| CN115040695B (zh) * | 2021-03-09 | 2023-10-13 | 南开大学 | 一种基于VE-cad-Fc/N-cad-Fc的融合蛋白活性界面的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT414097B (de) * | 2004-06-25 | 2006-09-15 | Petzelbauer Peter Dr | Pharmazeutische zubereitung zur behandlung von schock |
| CA2760642A1 (en) * | 2009-05-01 | 2010-11-04 | The University Of Tokyo | Anti-cadherin antibody |
| CN103582494A (zh) * | 2010-10-27 | 2014-02-12 | 纽约州立大学研究基金会 | 靶向e-钙粘着蛋白的可溶性细胞外结构域的组合物和用于癌症治疗的有关方法 |
-
2013
- 2013-03-15 US US14/385,351 patent/US20150037354A1/en not_active Abandoned
- 2013-03-15 JP JP2015500673A patent/JP2015514062A/ja active Pending
- 2013-03-15 CA CA2867456A patent/CA2867456A1/en not_active Abandoned
- 2013-03-15 CN CN201380024208.0A patent/CN104519899A/zh active Pending
- 2013-03-15 RU RU2014141114A patent/RU2014141114A/ru not_active Application Discontinuation
- 2013-03-15 EP EP13760736.2A patent/EP2844270A4/en not_active Withdrawn
- 2013-03-15 KR KR1020147028934A patent/KR20140138956A/ko not_active Withdrawn
- 2013-03-15 WO PCT/US2013/032656 patent/WO2013138790A1/en not_active Ceased
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2018
- 2018-01-29 US US15/882,513 patent/US20190008957A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20150037354A1 (en) | 2015-02-05 |
| RU2014141114A (ru) | 2016-05-10 |
| EP2844270A4 (en) | 2016-01-27 |
| US20190008957A1 (en) | 2019-01-10 |
| CN104519899A (zh) | 2015-04-15 |
| JP2015514062A (ja) | 2015-05-18 |
| CA2867456A1 (en) | 2013-09-19 |
| EP2844270A1 (en) | 2015-03-11 |
| WO2013138790A1 (en) | 2013-09-19 |
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