KR20140132392A - 신규한 수크로스 수송체를 포함하는 재조합 박테리아 - Google Patents
신규한 수크로스 수송체를 포함하는 재조합 박테리아 Download PDFInfo
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- KR20140132392A KR20140132392A KR1020147027717A KR20147027717A KR20140132392A KR 20140132392 A KR20140132392 A KR 20140132392A KR 1020147027717 A KR1020147027717 A KR 1020147027717A KR 20147027717 A KR20147027717 A KR 20147027717A KR 20140132392 A KR20140132392 A KR 20140132392A
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
- C12P7/20—Glycerol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/335—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Lactobacillus (G)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
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- C12N9/2431—Beta-fructofuranosidase (3.2.1.26), i.e. invertase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01007—Sucrose phosphorylase (2.4.1.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/01001—Hexokinase (2.7.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/01003—Ketohexokinase (2.7.1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/01004—Fructokinase (2.7.1.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01026—Beta-fructofuranosidase (3.2.1.26), i.e. invertase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/412,193 | 2012-03-05 | ||
| US13/412,193 US9017961B2 (en) | 2012-03-05 | 2012-03-05 | Recombinant bacteria comprising novel sucrose transporters |
| PCT/US2013/028970 WO2013134174A2 (en) | 2012-03-05 | 2013-03-05 | Recombinant bacteria comprising novel sucrose transporters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20140132392A true KR20140132392A (ko) | 2014-11-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147027717A Withdrawn KR20140132392A (ko) | 2012-03-05 | 2013-03-05 | 신규한 수크로스 수송체를 포함하는 재조합 박테리아 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US9017961B2 (OSRAM) |
| EP (1) | EP2822960A2 (OSRAM) |
| JP (1) | JP2015509379A (OSRAM) |
| KR (1) | KR20140132392A (OSRAM) |
| CN (1) | CN104302661A (OSRAM) |
| AU (1) | AU2013230162A1 (OSRAM) |
| CA (1) | CA2865014A1 (OSRAM) |
| IN (1) | IN2014DN06652A (OSRAM) |
| SG (1) | SG11201405338YA (OSRAM) |
| WO (1) | WO2013134174A2 (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| NZ593598A (en) | 2008-11-18 | 2013-02-22 | Beth Israel Hospital | Optimized antiviral vaccines with improved cellular immunogenicity |
| US9688967B2 (en) | 2014-12-05 | 2017-06-27 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with hyperammonemia |
| WO2016183532A1 (en) * | 2015-05-13 | 2016-11-17 | Synlogic, Inc. | Bacteria engineered to treat a disease or disorder |
| EP3294760B1 (en) | 2015-05-13 | 2021-03-24 | Synlogic Operating Company, Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| US11883439B2 (en) | 2015-05-13 | 2024-01-30 | Synlogic Operating Company, Inc. | Bacteria engineered to treat a disease or disorder |
| WO2017087580A1 (en) | 2015-11-16 | 2017-05-26 | Synlogic, Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| CN107058205B (zh) * | 2017-06-05 | 2020-05-08 | 江南大学 | 一种产蔗糖磷酸化酶的重组枯草芽孢杆菌及其应用 |
| AU2018290278B2 (en) | 2017-06-21 | 2022-12-15 | Synlogic Operating Company, Inc. | Bacteria for the treatment of disorders |
| CN108070579A (zh) * | 2017-12-21 | 2018-05-25 | 中诺生物科技发展江苏有限公司 | 一种蔗糖转化酶工业化生产方法 |
| CN108504616B (zh) * | 2018-04-03 | 2020-05-29 | 广西科学院 | 一种高效发酵蔗糖的重组拜氏梭菌以及提高拜氏梭菌蔗糖发酵性能的方法 |
| KR102201720B1 (ko) * | 2018-05-24 | 2021-01-12 | 한화솔루션 주식회사 | 1,3-pdo 생성능을 가지고 3-hp 생성능이 저해된 재조합 코리네박테리움 및 이를 이용한 1,3-pdo의 제조방법 |
| JP2023518184A (ja) | 2020-03-20 | 2023-04-28 | シンロジック オペレーティング カンパニー インコーポレイテッド | 高フェニルアラニン血症を軽減するように遺伝子改変された微生物 |
| CN117947025B (zh) * | 2023-11-07 | 2025-06-10 | 华南农业大学 | 黄梁木蔗糖转运基因NcSUT1启动子及其应用 |
| CN118086444B (zh) * | 2024-04-28 | 2024-06-28 | 山东德普新材料科技有限公司 | 一种发酵联产1,3-丙二醇和3-羟基丙酸的方法 |
Family Cites Families (17)
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| US5686276A (en) | 1995-05-12 | 1997-11-11 | E. I. Du Pont De Nemours And Company | Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism |
| BR9712761B1 (pt) | 1996-11-13 | 2010-02-23 | mÉtodo para a produÇço de 1,3- propanodiol e microorganismo hospedeiro transformado. | |
| CN1202253C (zh) | 1997-12-02 | 2005-05-18 | 纳幕尔杜邦公司 | 用重组生物体生产甘油的方法 |
| EP1204755B1 (en) | 1999-08-18 | 2006-08-09 | E.I. Du Pont De Nemours And Company | Process for the biological production of 1,3-propanediol |
| RU2212447C2 (ru) | 2000-04-26 | 2003-09-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Штамм escherichia coli - продуцент аминокислоты (варианты) и способ получения аминокислот (варианты) |
| US8192959B2 (en) | 2002-04-22 | 2012-06-05 | Genencor International Inc | Promoter and plasmid system for genetic engineering |
| US7371558B2 (en) | 2002-10-04 | 2008-05-13 | E.I. Du Pont De Nemours And Company | Process for the biological production of 1,3-propanediol with high yield |
| US7524660B2 (en) | 2005-05-05 | 2009-04-28 | E.I. Du Pont De Nemours And Company | Utilization of fructose in microbial production strains |
| BRPI0819509A2 (pt) | 2007-12-18 | 2014-10-14 | Korea Advanced Inst Sci & Tech | MICROORGANISMO E VETOR RECOMBINANTE, SACAROSE FOSFOTRANSFERASE, GENE (ptsG), BETA-FRUTOFURANOSIDASE E MÉTODO PARA PRODUZIR METABÓLITOCOS, POLÍMEROS BIODEGRADÁVEIS OU PROTEÍNAS RECOMBINANTES |
| KR101395971B1 (ko) | 2008-11-07 | 2014-05-16 | 메타볼릭 익스플로러 | 1,2-프로판디올의 발효에 의한 생산을 위한 기질로서의 수크로스의 사용 |
| US20110144377A1 (en) | 2009-06-16 | 2011-06-16 | E. I. Du Pont Nemours And Company | Process for the biological production of 3-hydroxypropionic acid with high yield |
| US20110136190A1 (en) | 2009-12-04 | 2011-06-09 | E. I. Du Pont De Nemours And Company | Recombinant bacteria for producing glycerol and glycerol-derived products from sucrose |
| US8129170B1 (en) | 2010-12-06 | 2012-03-06 | E.I. Du Pont De Nemours And Company | Recombinant bacteria having the ability to metabolize sucrose |
| US8222000B2 (en) | 2010-12-06 | 2012-07-17 | E I Du Pont De Nemours And Company | Recombinant bacteria having the ability to metabolize sucrose |
| US8629243B2 (en) | 2011-08-16 | 2014-01-14 | E I Du Pont De Nemours And Company | Variant sucrose transporter polypeptides that enable faster sucrose utilization in bacteria |
| US8673602B2 (en) * | 2011-08-16 | 2014-03-18 | E I Du Pont De Nemours And Company | Recombinant bacteria having improved sucrose utilization |
| US8686114B2 (en) | 2012-03-05 | 2014-04-01 | E I Du Pont De Nemours And Company | Variant sucrose transporter polypeptides |
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2012
- 2012-03-05 US US13/412,193 patent/US9017961B2/en not_active Expired - Fee Related
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2013
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- 2013-03-05 CN CN201380012400.8A patent/CN104302661A/zh active Pending
- 2013-03-05 CA CA2865014A patent/CA2865014A1/en not_active Abandoned
- 2013-03-05 KR KR1020147027717A patent/KR20140132392A/ko not_active Withdrawn
- 2013-03-05 IN IN6652DEN2014 patent/IN2014DN06652A/en unknown
- 2013-03-05 SG SG11201405338YA patent/SG11201405338YA/en unknown
- 2013-03-05 JP JP2014561008A patent/JP2015509379A/ja active Pending
- 2013-03-05 AU AU2013230162A patent/AU2013230162A1/en not_active Abandoned
- 2013-03-05 US US14/382,343 patent/US20150064755A1/en not_active Abandoned
- 2013-03-05 EP EP13709706.9A patent/EP2822960A2/en not_active Withdrawn
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2015
- 2015-04-01 US US14/676,456 patent/US20150203876A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IN2014DN06652A (OSRAM) | 2015-05-22 |
| WO2013134174A3 (en) | 2013-12-27 |
| AU2013230162A1 (en) | 2014-08-28 |
| US20150203876A1 (en) | 2015-07-23 |
| CN104302661A (zh) | 2015-01-21 |
| JP2015509379A (ja) | 2015-03-30 |
| US9017961B2 (en) | 2015-04-28 |
| US20150064755A1 (en) | 2015-03-05 |
| SG11201405338YA (en) | 2014-09-26 |
| CA2865014A1 (en) | 2013-09-12 |
| US20130230893A1 (en) | 2013-09-05 |
| WO2013134174A2 (en) | 2013-09-12 |
| EP2822960A2 (en) | 2015-01-14 |
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