KR20140084211A - 효과가 없는 적혈구생성 치료를 위한 방법 및 조성물 - Google Patents

효과가 없는 적혈구생성 치료를 위한 방법 및 조성물 Download PDF

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Publication number
KR20140084211A
KR20140084211A KR1020147013325A KR20147013325A KR20140084211A KR 20140084211 A KR20140084211 A KR 20140084211A KR 1020147013325 A KR1020147013325 A KR 1020147013325A KR 20147013325 A KR20147013325 A KR 20147013325A KR 20140084211 A KR20140084211 A KR 20140084211A
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actriib
anemia
gdf trap
seq
amino acid
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Ceased
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KR1020147013325A
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English (en)
Korean (ko)
Inventor
자스비르 시헤라
로버트 스콧 피어설
라빈드라 쿠마르
나가 벤카타 사이 라자세하르 수라가니
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악셀레론 파마 인코포레이티드
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Publication of KR20140084211A publication Critical patent/KR20140084211A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11Protein-serine/threonine kinases (2.7.11)
    • C12Y207/1103Receptor protein serine/threonine kinase (2.7.11.30)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020147013325A 2011-10-17 2012-10-17 효과가 없는 적혈구생성 치료를 위한 방법 및 조성물 Ceased KR20140084211A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161547932P 2011-10-17 2011-10-17
US61/547,932 2011-10-17
PCT/US2012/060650 WO2013059347A1 (en) 2011-10-17 2012-10-17 Methods and compositions for treating ineffective erythropoiesis

Related Child Applications (1)

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KR1020197025484A Division KR102079482B1 (ko) 2011-10-17 2012-10-17 비효율적 적혈구생성 치료를 위한 방법 및 조성물

Publications (1)

Publication Number Publication Date
KR20140084211A true KR20140084211A (ko) 2014-07-04

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KR1020197025484A Active KR102079482B1 (ko) 2011-10-17 2012-10-17 비효율적 적혈구생성 치료를 위한 방법 및 조성물
KR1020227017193A Ceased KR20220075438A (ko) 2011-10-17 2012-10-17 비효율적 적혈구생성 치료를 위한 방법 및 조성물
KR1020147013325A Ceased KR20140084211A (ko) 2011-10-17 2012-10-17 효과가 없는 적혈구생성 치료를 위한 방법 및 조성물
KR1020207004201A Ceased KR20200019261A (ko) 2011-10-17 2012-10-17 비효율적 적혈구생성 치료를 위한 방법 및 조성물

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KR1020197025484A Active KR102079482B1 (ko) 2011-10-17 2012-10-17 비효율적 적혈구생성 치료를 위한 방법 및 조성물
KR1020227017193A Ceased KR20220075438A (ko) 2011-10-17 2012-10-17 비효율적 적혈구생성 치료를 위한 방법 및 조성물

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US (4) US20130243743A1 (enExample)
EP (3) EP2797620B1 (enExample)
JP (4) JP6092883B2 (enExample)
KR (4) KR102079482B1 (enExample)
CN (3) CN107837390A (enExample)
AU (4) AU2012326207B2 (enExample)
BR (3) BR112014009528B1 (enExample)
CA (1) CA2852683A1 (enExample)
DK (2) DK3875104T3 (enExample)
EA (2) EA034563B1 (enExample)
ES (3) ES3010483T3 (enExample)
HK (2) HK1250341A1 (enExample)
WO (1) WO2013059347A1 (enExample)

Cited By (1)

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KR20180006437A (ko) * 2015-05-13 2018-01-17 셀진 코포레이션 Actrii 리간드 트랩을 사용한 베타-탈라세미아의 치료

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JP6649895B2 (ja) * 2014-04-18 2020-02-19 アクセルロン ファーマ, インコーポレイテッド 赤血球レベルを増加させ、そして鎌状赤血球症を処置するための方法
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KR20180006437A (ko) * 2015-05-13 2018-01-17 셀진 코포레이션 Actrii 리간드 트랩을 사용한 베타-탈라세미아의 치료

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US20170137791A1 (en) 2017-05-18
US20170327800A1 (en) 2017-11-16
AU2017201580A1 (en) 2017-03-30
EP3520805B1 (en) 2021-03-10
CN107693776A (zh) 2018-02-16
EP2797620A4 (en) 2015-05-20
CN103987403B (zh) 2017-12-01
AU2017201580B2 (en) 2018-07-12
CN103987403A (zh) 2014-08-13
BR122019023166B1 (pt) 2021-02-23
US20130243743A1 (en) 2013-09-19
JP6796626B2 (ja) 2020-12-09
DK3520805T3 (da) 2021-04-19
AU2018247262B2 (en) 2020-12-24
CN107837390A (zh) 2018-03-27
EA202090053A2 (ru) 2020-04-30
EA202090053A3 (ru) 2020-06-30
BR112014009528B1 (pt) 2020-12-29
HK1203413A1 (en) 2015-10-30
KR20220075438A (ko) 2022-06-08
AU2012326207A1 (en) 2014-05-15
EA201490809A1 (ru) 2014-09-30
EP3520805A1 (en) 2019-08-07
EP2797620A1 (en) 2014-11-05
AU2020286229A1 (en) 2021-01-07
KR102079482B1 (ko) 2020-02-19
BR122019023174B1 (pt) 2021-02-23
KR20190105113A (ko) 2019-09-11
BR112014009528A8 (pt) 2019-12-10
EP2797620B1 (en) 2019-04-24
EA034563B1 (ru) 2020-02-20
WO2013059347A1 (en) 2013-04-25
JP2014530253A (ja) 2014-11-17
JP2020186277A (ja) 2020-11-19
ES3010483T3 (en) 2025-04-03
US20210207107A1 (en) 2021-07-08
AU2012326207B2 (en) 2016-12-15
JP6092883B2 (ja) 2017-03-08
EP3875104B1 (en) 2025-01-22
HK1252940A1 (zh) 2019-06-06
AU2018247262A1 (en) 2018-11-01
ES2869168T3 (es) 2021-10-25
DK3875104T3 (da) 2025-02-03
CA2852683A1 (en) 2013-04-25
KR20200019261A (ko) 2020-02-21
JP6383821B2 (ja) 2018-08-29
ES2741477T3 (es) 2020-02-11
JP2018165287A (ja) 2018-10-25
HK1250341A1 (zh) 2018-12-14
JP2017101060A (ja) 2017-06-08
EP3875104A1 (en) 2021-09-08
BR112014009528A2 (pt) 2017-05-09

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