KR20140036822A - Manufacturing method of a functional composition for preventing cancer containing chive extrect, a functional composition for preventing cancer containing chive extrect manufactured by the same and a functional food for preventing cancer containing therof - Google Patents
Manufacturing method of a functional composition for preventing cancer containing chive extrect, a functional composition for preventing cancer containing chive extrect manufactured by the same and a functional food for preventing cancer containing therof Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
- A23L2/04—Extraction of juices
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/70—Clarifying or fining of non-alcoholic beverages; Removing unwanted matter
- A23L2/72—Clarifying or fining of non-alcoholic beverages; Removing unwanted matter by filtration
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/308—Foods, ingredients or supplements having a functional effect on health having an effect on cancer prevention
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2300/00—Processes
- A23V2300/14—Extraction
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2300/00—Processes
- A23V2300/24—Heat, thermal treatment
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- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to anti-cancer functional food using three, the mixing step of grinding and mixing the three to 0.1 ~ 1cm (step 1); Dipping step of mixing the crushed three with purified water for 10 to 14 hours at 20 ~ 25 ℃ (step 2); Extraction step (step 3) for extracting the immersion in the immersion step for 2-6 hours at 90 ~ 100 ℃; And a filtration step (step 4) of filtering the extract extracted in the extraction step. It is characterized by including the technical features, and by mixing the three extracts with leek and buttercups, there is an effect to prevent constipation as well as cancer.
Description
The present invention relates to a method for producing an anticancer functional composition using three, an anticancer functional composition using three manufactured by the same, and an anticancer functional food using three, including the same. More specifically, by mixing leek and buttercup in three extracts By manufacturing, the present invention relates to a method for producing an anticancer functional composition using three, which is effective in preventing cancer as well as constipation, and an anticancer functional composition using the three produced thereby, and an anticancer functional food using three.
Cancer, unlike normal cells that can proliferate and inhibit regular and resected proliferation according to the needs of an individual, is composed of undifferentiated cells that unlimitedly proliferate in a tissue and form a mass or tumor. Refers to a group of diseases that can invade and destroy surrounding normal tissues or organs, and can transfer any organ of an individual from the primary path to create a new place of growth, thereby taking the individual's life away.
Cancers are classified into pathologically malignant tumors of epithelial cells and sarcomas of malignant tumors of non-epithelial cells, depending on the tissue cells from which the primary pathology originates. Cancers are squamous cell carcinoma, adenocarcinoma, and basal cell. It is subdivided into inclusions, melanoma, and the like, and sarcomas may be subdivided into fibromas, osteosarcomas, angiosarcomas, lymph node cancers, leukemias, and myomas.
The pathogenesis of cancer is divided into normal cell changes and immune system abnormalities. Normal cell changes become cancer cells when the normal cells are exposed to risk factors causing genetic mutations, and thus cancer occurs. Exposure of normal cells to smoking, carcinogenic foods, chemicals, and carcinogenic pathogens, which are known as risk factors, causes mutations in genes. About 10 to 20 $ of cancers are caused by abnormal genes inherited from parents. Are affected.
Among the components of the cell nucleus, there is a substance called DNA, and the structure of the DNA is changed to produce cancer cells, and the modified cells continue to have modified DNA even when they divide. These changes are not temporary, and cancer usually develops through the accumulation of several types of genetic mutations over 20-30 years.
The body's normal immune function is capable of destroying up to 10 million tumor cells produced in the body, but it usually contains at least 1 billion tumor cells when the cancer cells divide and proliferate to the extent that cancer is found clinically. Therefore, far beyond the level that can be destroyed by immune function, cancer cells are not removed and cancer occurs.
Major causes of cancer development include smoking, drinking, occupational exposure to various carcinogens, environmental pollution, exposure to ionizing radiation, ultraviolet radiation, various drugs, and viruses. In the case of colorectal cancer and breast cancer, genetic predisposition may have an important effect, and 80-90% of all cancers may be caused by lifestyle and environmental factors, thereby improving lifestyle and environmental factors. Cancer can be prevented through.
From the medical point of view, the World Health Organization is able to prevent one-third of primary cancers, one-third of the population can be cured by early diagnosis, and one-third of patients can be alleviated with proper treatment. Since cancer is usually not present in the early stages of the disease, it is often detected after considerable progression, so prevention is important. Gastric cancer, liver cancer, breast cancer, cervical cancer, and colon cancer, which are common in Korea, may be detected early. Because of the high rate of cure, these cancers require regular checkups, lung cancer can be prevented by quitting smoking, and liver cancer can be prevented by vaccination with hepatitis.
The main purpose of cancer treatment is to heal the patient by restoring the structural and functional damage caused by the cancer, and to prolong life and improve the quality of life by preventing further cancer progression and alleviating symptoms if it is not possible. There are three types of methods: surgery therapy, chemotherapy, and radiation therapy. In addition, there are local therapy, hormone therapy, photodynamic therapy, and laser therapy. Recently, immunotherapy and gene therapy are being developed. .
Surgical therapy can be divided into four types according to its purpose: diagnostic surgery, radical surgery, preventive surgery, palliative surgery. Through diagnostic surgery, tumor classification and type can be identified and confirmed. In addition, the commonly used radical surgery removes both lymph nodes and primary lesions surrounding the tumor, including radical mastectomy or radical hysterectomy, and precancerous lesions such as warts and polyps. It is prophylactic to prevent the development of cancer by leaving it untreated, i.e. to remove harmless precancerous lesions, and palliative surgery slows tumor growth by reducing the size of the tumor and thereby To alleviate the symptoms.
Chemotherapy is the destruction of all harmful cancer cells without excessive destruction of normal cells, which are used to inhibit cancer growth when treatment is no longer possible, and recently cancer cells that remain after surgery or radiotherapy Adjuvant therapy to completely eliminate the or preoperative surgery to reduce the size of the cancer is a trend that is widely used as a pre-treatment, easy to operate, can be largely divided into combination therapy, combined therapy, combination therapy, preoperative surgery.
However, since all anticancer drugs destroy not only cancer cells but also normal cells, patients receiving anticancer drugs may experience side effects due to anticancer drugs such as bone marrow dysfunction, gastrointestinal disorders, alopecia, reduced white blood cells, reduced platelets, anemia, vomiting, Digestive disorders such as loss of appetite, stomatitis and diarrhea, pulmonary disorders such as interstitial pneumonia and pulmonary fibrosis, skin changes, nervous system disorders, heart disorders, liver disorders, urinary disorders, and genital disorders.
Therapeutic radiation means high energy enough to destroy cancer cells, and the role of radiation therapy is divided into primary treatment, adjuvant treatment, and palliative treatment.In advanced cancer, pain, pathological fracture, cerebral spinal relative vein, etc. It is used to relieve symptoms such as obstruction of blood vessels in major organs.
Most cancers need to be treated for a long time, but the earlier the treatment, the better the therapeutic effect, despite the development of various medicines are not known to have a high cure rate, the current commercially available drugs have a weak effect.
In recent years, researches are being actively conducted to overcome the side effects of cancer treatment in Western medicine.
Korean Patent Publication No. 10-0456089 (2004.11.09.) Discloses a method for purifying wild ginseng extract tablets having anticancer activity and a composition containing the same, and Korean Patent Publication No. 10-0759579 (2007.09. 18.) discloses a soybean extract having an anticancer effect and a functional food containing the same, and Korean Patent Publication No. 10-0624100 (2006.09.18.) Includes an anticancer composition comprising an extract of mushrooms cultured in Injin mugwort Is disclosed.
The anticancer compositions disclosed in the patent have the advantage that there are no side effects because they use natural plants, but patents on anticancer functional foods using three are not disclosed.
Thus, the present inventors made an effort to develop an anticancer functional composition containing three extracts as an active ingredient, and as a result of mixing the three extracts with leek and buttercups, anticancer using three cancers effective in preventing as well as constipation. Functional compositions have been developed.
An object of the present invention is to prepare a mixture of leek and buttercups in three extracts, anti-cancer functional composition using the three effective to prevent cancer as well as constipation prevention, anti-cancer functional composition using the three produced thereby It is to provide anti-cancer functional food using three containing.
In order to achieve the above object, the present invention provides the following means.
The present invention is a mixing step (step 1) of grinding and mixing the three to 0.1 ~ 1cm; Dipping step of mixing the crushed three with purified water for 10 to 14 hours at 20 ~ 25 ℃ (step 2); Extraction step (step 3) for extracting the immersion in the immersion step for 2-6 hours at 90 ~ 100 ℃; And a filtration step (step 4) of filtering the extract extracted in the extraction step. It provides a method for producing an anticancer functional composition using three, characterized in that it comprises a.
In step 1, the leek 5 to 10 parts by weight and 1 to 5 parts by weight of parsley is characterized in that the addition of 100 parts by weight.
In another aspect, the present invention provides an anti-cancer functional composition using three, characterized in that the production method.
In another aspect, the present invention provides an anti-cancer functional food using the three, characterized in that it comprises the composition.
Anti-cancer functional food using the three according to the present invention is produced by mixing the leek and buttercups in three extracts, there is an effect to prevent constipation as well as cancer.
Hereinafter, the present invention will be described in detail.
First, a method for producing an anticancer functional composition using three vegetables according to the present invention will be described.
Method for producing an anticancer functional composition using the three of the present invention,
Mixing step (step 1) to grind and mix the three vegetables, leek and buttercup to 0.1 ~ 1cm respectively;
Dipping step (step 2) of mixing the purified water to the mixture for 10 to 14 hours immersion at 20 ~ 25 ℃;
Extraction step (step 3) for extracting the immersion in the immersion step for 2-6 hours at 90 ~ 100 ℃; And
A filtration step (step 4) of filtering the extract extracted in the extraction step;
.
It is preferable to mix 5 to 10 parts by weight of leek and 1 to 5 parts by weight of buttercup per 100 parts by weight of the three in step 1.
The three are scientific name Allium, and grows in super high altitudes above 1,400m above sea level, has a spicy taste, sweetness, bitter taste, and is rich in vitamin C, calcium, iron, etc. It contains six times more ingredients than garlic. The three is preferably used to dry the stem and root.
The Chinese leek (Chinese Chive) is a perennial herb belonging to the family Liliaceae, its properties are slightly warm, taste is sour and hot. Leek is a food rich in vitamins A and C and has a tonic effect, such as garlic.
The dropwort (Dropwort) is a perennial herb that is native to Korea and grows in wet places near fields, wetlands, and water. In oriental medicine, leaves and stems are used as a medicinal herb, which has a high fever, which makes the chest feel stuffy and thirsty, and diuretic, swelling, and tonic and detoxification effect.
Step 2 is an immersion step of immersing 10-30 times by weight of purified water of the total weight of the mixture in the mixture for 10 to 14 hours at 20 ~ 25 ℃. The immersion step is to be carried out in order to better elute the nutrients of three, leek and buttercup in the hot water extraction step.
Step 3 is an extraction step of extracting the immersion in the immersion step for 2-6 hours at 90 ~ 100 ℃.
Step 4 is a filtration step of filtering the extract extracted in the extraction step.
In addition, the present invention provides an anticancer functional composition which is effective in preventing cancer and preventing constipation prepared by the above method.
The anticancer functional composition according to the present invention is prepared by mixing three extracts, leek extract and buttercup extract, it is effective in preventing cancer as well as constipation.
In addition, the present invention provides an anticancer functional food comprising the anticancer functional composition.
The anticancer functional composition of the present invention can be prepared into a health functional food in the form of a preparation by further comprising a food additive which is acceptable as a food, and can be tablets, capsules, pills, liquids, and the like. .
Hereinafter, the constitution and effects of the present invention will be described in more detail through examples. These embodiments are only for illustrating the present invention, and the scope of the present invention is not limited by these embodiments.
Three slices, leeks and buttercups are cut and dried to a size of 0.5 ~ 1cm, and mixed with 100g three g Leek 8g and 3g root, 2 liters of distilled water was added and soaked for 12 hours at 23 ℃. The immersion was extracted with hot water at 90 ° C. for 3 hours, cooled, and filtered through a filter paper (whatman No. 2) to prepare an anticancer functional composition.
Comparative Example 1
Except for not including the leek and buttercup in Example 1 the rest of the same was prepared anti-cancer functional composition.
[Comparative Example 2]
Except for not including the leek in Example 1 was prepared in the same way as the rest of the anti-cancer functional composition.
[Comparative Example 3]
The anticancer functional composition was prepared in the same manner as in Example 1 except that the buttercup was not included.
[Experimental Example 1]
In order to confirm the efficacy of the anticancer functional composition of Example 1, Comparative Examples 1 to 3, the anticancer of Example 1, Comparative Examples 1 to 3 for 90 days for 40 male and female adults diagnosed with cancer early The functional composition was drunk 100 ml each morning and evening.
The average age of the experimenters was 65.2 years old, the average body weight was 64.4kg male, 51.2kg female, the average height was 167.2cm male and 156.4cm female.
Table 1 shows the results after investigating the anticancer effect in the experimenter.
Referring to Table 1, the composition of Example 1 containing three extracts, leek and buttercup extract, the composition of Comparative Example 1 containing only three extracts, the composition of Comparative Example 2 containing three extracts, buttercup extract, three, leek extract It can be seen that the anticancer effect is superior to that of the composition of Comparative Example 3 containing.
[Experimental Example 2]
In order to confirm the constipation improvement efficacy of Example 1, Comparative Examples 1 to 3, 40 adult men and women suffering from constipation, the functional composition of Example 1, Comparative Examples 1 to 3 for 30 days In the morning and evening, 100 ml each was drunk.
The average age of the test subjects was 54.1 years old, and the average weight was 75.3 kg for males, 62.6 kg for females, and the average height was 170.1 cm for males and 159.5 cm for females.
Table 2 shows the results after investigating the effect of toilet improvement on the experimenter.
Referring to Table 2, the composition of Example 1 containing three extracts, leek and buttercup extract, the composition of Comparative Example 1 containing only three extracts, the composition of Comparative Example 2 containing three extracts, buttercup extract, three, leek extract It can be seen that the constipation improvement effect is more excellent than the composition of Comparative Example 3 containing.
Claims (4)
Dipping step of mixing the crushed three with purified water for 10 to 14 hours at 20 ~ 25 ℃ (step 2);
Extraction step (step 3) for extracting the immersion in the immersion step for 2-6 hours at 90 ~ 100 ℃; And
A filtration step (step 4) of filtering the extract extracted in the extraction step;
Method for producing an anticancer functional composition using three, characterized in that it comprises a.
Method for producing an anticancer functional composition using three vegetables, characterized in that for adding 5 to 10 parts by weight of leek and 1 to 5 parts by weight of buttercup relative to 100 parts by weight of the three vegetables.
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| KR1020120103417A KR20140036822A (en) | 2012-09-18 | 2012-09-18 | Manufacturing method of a functional composition for preventing cancer containing chive extrect, a functional composition for preventing cancer containing chive extrect manufactured by the same and a functional food for preventing cancer containing therof |
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| KR1020120103417A KR20140036822A (en) | 2012-09-18 | 2012-09-18 | Manufacturing method of a functional composition for preventing cancer containing chive extrect, a functional composition for preventing cancer containing chive extrect manufactured by the same and a functional food for preventing cancer containing therof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150141294A (en) | 2014-06-10 | 2015-12-18 | 목포대학교산학협력단 | An antibacterial composition comprising an extract of allilum hookeri |
| KR20160025418A (en) | 2014-08-27 | 2016-03-08 | 목포대학교산학협력단 | Method of manufacturing vegetable juice with improved health functions using Allium Hookeri and vegetable juice manufactured by the method |
| WO2017082524A1 (en) * | 2015-11-10 | 2017-05-18 | 대한민국(농촌진흥청장) | Pharmaceutical composition for inhibiting tumors, containing allium hookeri extract as active ingredient |
| KR20190074600A (en) * | 2017-12-20 | 2019-06-28 | 주식회사 씨오푸드 | Method for Manufacturing Allium hookeri Sap |
-
2012
- 2012-09-18 KR KR1020120103417A patent/KR20140036822A/en not_active Application Discontinuation
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150141294A (en) | 2014-06-10 | 2015-12-18 | 목포대학교산학협력단 | An antibacterial composition comprising an extract of allilum hookeri |
| KR20160025418A (en) | 2014-08-27 | 2016-03-08 | 목포대학교산학협력단 | Method of manufacturing vegetable juice with improved health functions using Allium Hookeri and vegetable juice manufactured by the method |
| WO2017082524A1 (en) * | 2015-11-10 | 2017-05-18 | 대한민국(농촌진흥청장) | Pharmaceutical composition for inhibiting tumors, containing allium hookeri extract as active ingredient |
| KR20190074600A (en) * | 2017-12-20 | 2019-06-28 | 주식회사 씨오푸드 | Method for Manufacturing Allium hookeri Sap |
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