KR20130117754A - Pesticidal composition comprising a benzoylurea compound and chlorfenapyr and their uses - Google Patents

Abstract

(상기 식에서, R, R¹, R², R³, n, R⁴, R⁵는 명세서에 정의된 바와 같음)
<화학식 II>

본 발명은 또한 무척추동물 해충을 퇴치 방제, 퇴치하기 위한 조성물의 용도에 관한 것이다. 또한, 본 발명은 또한 이러한 조성물을 적용하는 방법에 관한 것이다.Insecticidal compositions comprising benzoylurea compounds and chlorfenapyr and uses thereof
The present invention relates to an insecticidal composition comprising a insecticidal benzoylurea compound of formula (I) and a compound of formula (II) in a synergistically effective amount. The compounds of the formulas (I) and (II) according to the invention are represented by the formula:-compounds of the formula (I); Defined by compounds of formula (II).
(I)

(Wherein R, R ¹ , R ² , R ³ , n, R ⁴ , R ⁵ are as defined in the specification)
<Formula II>

The invention also relates to the use of the composition for controlling and combating invertebrate pests. The invention also relates to a method of applying such a composition.

Description

Insecticidal compositions comprising a benzoylurea compound and chlorfenapyr and uses thereof {PESTICIDAL COMPOSITION COMPRISING A BENZOYLUREA COMPOUND AND CHLORFENAPYR AND THEIR USES}

The present invention relates to insecticidal compositions comprising insecticide benzoylurea compounds of formula (I) and compounds of formula (II) as defined below, and to the use of such compositions for controlling invertebrate pests.

Despite the commercial insecticides, acaricides and nematicides currently available, the damage caused by insects, arachnids and nematodes in both growing and harvested crops still occurs. Therefore, there is a continuing need for the development of new insecticides, acaricides and nematicides.

One typical problem arising in the field of pest control is the need to reduce the rate of application of the active ingredient to reduce or avoid adverse environmental or toxin effects while still enabling effective pest control.

Another problem encountered relates to the need to have available pest control agents that are very effective against a broad spectrum of pests.

There is also a need for pest control agents that combine rust-down activity with prolonged control, ie a combination of fast action and long lasting action.

Another problem associated with the use of pesticides is that repeated application and application of individual pesticidal compounds alone leads to the rapid selection of pests that express natural or adaptive resistance to the active compound in many cases. Thus there is a need for pest control agents that help prevent or overcome resistance.

It is therefore an object of the present invention to provide novel insecticides and novel methods for controlling insects, arachnids or nematodes and for protecting growing plants from attack or invasion by insects, arachnids or nematodes, and also novel methods for protecting seeds from insects. To provide.

It is therefore an object of the present invention to provide pesticides that address one or more of the issues discussed by reducing application rates and / or enhancing the spectrum of activity and / or combining knock-down activity with prolonged control and / or managing tolerance. It is.

The benzoylurea compounds of formula (I) as well as their pesticidal activity are known, for example, from US 5874615 or EP 0161019.

US 4698365 and US 4623658 disclose benzoylurea compounds having insecticidal activity, in particular insecticidal and acaricide properties.

EP 0347488 describes chlorfenapyr and derivative compounds and mentions their use in mixtures with other insecticides.

US 4666942 discloses the use of benzoylurea compounds as insecticidal compositions comprising benzoylurea in combination with other compounds having insecticidal properties, in particular organophosphates and pyrethroids.

CN 1364413 discloses a composition having insecticidal activity comprising chlorfenapyr and one or more selected insecticidal compounds.

JP 2006056810 discloses pesticidal compositions comprising benzoylurea compounds and also mentions pesticidal methods for harmful insects living in water.

In order to combat the harmful insects that can cause great damage to crops and other plants and to solve the problems mentioned above, efficient compositions with effective and high insecticidal activity are still needed.

We have found that these objects are achieved in part or in whole by the combination of active compounds as defined below. In addition, the inventors have found that simultaneous, ie joint or separate application of the active compounds of formula (I) and compounds of formula (II), or the continuous application of compounds (I) and (II) enables enhanced control of pests compared to the control rates possible with the individual compounds. I found that.

Surprisingly, it has now been found that by mixing the benzoylurea of formula (I) with the active compound of formula (II), the object of the invention can be at least achieved in certain aspects.

Thus, one aspect of the present invention is an active ingredient,

1) Benzoylurea compound of formula (I) or an agriculturally acceptable salt thereof; And

<Formula I>

(Wherein,

R is halogen, C ₁ -C ₄ alkyl, C ₁ -C ₄ alkoxy or C ₁ -C ₄ alkylthio;

R ¹ is hydrogen, halogen, C ₁ -C ₄ alkyl, C ₁ -C ₄ alkoxy or C ₁ -C ₄ alkylthio;

R ² is fluorine;

R ³ is hydrogen, halogen, nitro, cyano, C ₁ -C ₄ alkyl or C ₁ -C ₄ haloalkyl;

n is an integer of 0, 1, 2 or 3;

R ⁴ is halogen or OR ⁵ ;

R ⁵ is substituted with up to 3 groups independently selected from C ₁ -C ₄ haloalkyl, C ₃ -C ₇ halocycloalkyl, phenyl which is halogen, C ₁ -C ₄ haloalkyl group, cyano group or nitro group Or may be unsubstituted), 2-pyridyl (may or may not be substituted with up to 3 groups independently selected from halogen atoms, C ₁ -C ₄ haloalkyl groups, cyano groups or nitro groups) being)

2) a compound of formula (II) or an agriculturally acceptable salt thereof

&Lt;

It provides a pesticidal composition comprising a synergistically effective amount.

The generic name of the compound of formula II is chlorfenapyr, ie, 4-bromo-2- (4-chlorophenyl) -1- (ethoxymethyl) -5- (trifluoromethyl) -1H-pyrrole-3 Carbonitrile.

The inventors have therefore found that some objects can be achieved by a composition as defined herein, ie by combining one or more benzoylurea compounds of formula (I) with compounds of formula (II).

Moreover, the present invention provides a method for combating and / or controlling pests, in particular invertebrate pests, insects, arachnids or nematodes, by using a composition comprising a synergistically effective amount of a compound of formulas (I) and (II), and methods of making such compositions It is about.

The invention also relates to a method of treating and / or protecting a plant from attack or infestation of pests, comprising contacting the plant or the soil or water on which the plant is growing with the composition according to the invention.

Moreover, the present invention also relates to a method for protecting a plant propagation material and / or a plant growing therefrom comprising treating the plant propagation material with a composition according to the invention.

The invention also provides the use of a composition comprising a compound of formula (I) and a compound of formula (II) for the protection of seeds, and the protection of seeds comprising contacting the seeds with a composition of the invention before sowing and / or after germination. It's about the way.

The term "pest" as used herein is considered to include any harmful organism, including insects, ticks and nematodes.

As used herein, as well as in the context of terms such as C ₁ -C ₄ alkoxy, C ₁ -C ₄ haloalkyl or C ₁ -C ₄ haloalkoxy, the term “C ₁ -C ₄ alkyl” means It refers to straight or branched aliphatic alkyl groups having four carbon atoms, for example methyl, ethyl, propyl, isopropyl, n-butyl, sec-butyl and tert-butyl.

As used herein, as well as in the context of terms such as “haloalkyl” or “haloalkoxy”, the term “halogen” refers to fluorine (F), chlorine (Cl), iodine (I) and bromine ( Br), preferably fluorine and chlorine, more preferably fluorine.

As used herein, the term “C ₁ -C ₄ alkoxy” refers to a C ₁ -C ₄ alkyl group as defined above, connected via an oxygen atom, for example methoxy, ethoxy, propoxy, isopropoxy, n- Butoxy, sec-butoxy and tert-butoxy.

As used herein, the term “C ₁ -C ₄ haloalkyl” is as defined above additionally containing one or more, for example 2, 3, 4, 5 or 6 halogen atom (s) as defined above. Same C ₁ -C ₄ alkyl groups such as mono-, di- and trifluoromethyl, mono-, di- and trichloromethyl, 1-fluoroethyl, 1-chloroethyl, 2-fluoroethyl, 2-chloroethyl, 1,1-difluoroethyl, 1,1-dichloroethyl, 1,2-difluoroethyl, 1,2-dichloroethyl, 2,2-difluoroethyl, 2,2- Dichloroethyl, 2,2,2-trifluoroethyl and 2,2,2-trichloroethyl.

As used herein, the term “C ₁ -C ₄ haloalkoxy” is as defined above further containing one or more, eg 2, 3, 4, 5 or 6 halogen atom (s) as defined above. Same C ₁ -C ₄ alkoxy groups, for example mono-, di- and trifluoromethoxy, mono-, di- and trichloromethoxy, 1-fluoroethoxy, 1-chloroethoxy, 2-fluoro Ethoxy, 2-chloroethoxy, 1,1-difluoroethoxy, 1,1-dichloroethoxy, 1,2-difluoroethoxy, 1,2-dichloroethoxy, 2,2-di Fluoroethoxy, 2,2-dichloroethoxy, 2,2,2-trifluoroethoxy and 2,2,2-trichloroethoxy.

As used herein, the term “C ₁ -C ₄ -alkylthio” refers to a C ₁ -C ₄ -alkyl group as defined above attached through a sulfur atom.

The term "C ₃ -C ₆ -cycloalkyl" as used herein refers to a mono- or non- or polycyclic saturated hydrocarbon radical having 3 to 6 carbon atoms. Examples of monocyclic radicals having 3 to 6 carbon atoms include cyclopropyl, cyclobutyl, cyclopentyl and cyclohexyl.

As used herein, the term “C ₃ -C ₆ -halocycloalkyl”, also represented as “C ₃ -C ₆ -cycloalkyl, which may be substituted by halogen,” and halo in halocycloalkoxy, halocycloalkylcarbonyl, and the like. The cycloalkyl moiety is a mono- having 3 to 6 carbon ring members (as mentioned above), in which some or all of the hydrogen atoms are replaced by halogen atoms as mentioned above, in particular fluorine, chlorine and bromine. Or non- or polycyclic saturated hydrocarbon groups (“C ₃ -C ₆ -halocycloalkyl”).

In a preferred embodiment of the invention, the substituents R ¹ , R ² , R ³ and R ⁴ in the benzoylurea compound of formula I have the preferred meanings given below independently of one another, but in particular in combination:

R is F, Cl or OCH ₃ , preferably F;

R ¹ is H, F, Cl or CH ₃ , preferably F;

R ³ is H, F or Cl, preferably hydrogen (H);

R ⁴ is F, Cl or OR ⁵ , preferably OR ⁵ ;

R ⁵ is C ₁ -C ₄ haloalkyl, phenyl substituted with one to three halogen atoms or a CF ₃ group, preferably a 4- (trifluoromethyl) phenyl group which may be substituted by halogen.

In a preferred embodiment, the benzoylurea compound of formula (I) is flufenoxuron, ie R and R ¹ are F, R ³ is hydrogen, and R ⁴ is 2-Cl-4-CF ₃ -phenoxy (ie CF ₃ is Cl at the para position the composition of the insecticidal compound of formula (I) placed in the ortho position) of the phenoxy group is preferred. Flufenoxuron is 1- [4- (N-[[[4- [2-chloro-4- (trifluoromethyl) phenoxy] -2-fluorophenyl] amino] carbonyl] -2,6 A generic name for difluorobenzamide (IUPAC nomenclature is 1- [4- (2-chloro-α, α, α-trifluoro-p-tolyloxy) -2-fluorophenyl] -3- (2,6-difluorobenzoyl) ureaim) having the general formula (Ia)

<Formula Ia>

Flufenoxulon of formula la, its preparation and its pesticidal activity are known from the literature (see US 5874615 and US 4698365).

Chlorfenapyr of formula (II), its preparation and its pesticidal activity are likewise known from the literature (see EP-A 376 279 and EP-A 375 907).

More preferably, the composition of the present invention is a combination of a synergistically effective amount of a benzoylurea compound of formula (Ia) (flufenoxalone) and a compound of formula (II) (chlorfenapyr), which is referred to as "composition A".

The composition of the present invention comprises a benzoylurea compound of formula (I) as component (1) and a compound of formula (II) as component (2) in a synergistically effective amount.

In general, a "synergistically effective amount" means that component (1) and component (2) and optionally further active pesticidal components are usually combined with the insecticidal effect of the two or more components, with the individual insecticidal effect of each compound. It means to be applied in a weight ratio to be greater than the sum of. The synergistic ratio of component (1): component (2) according to the invention is from 1: 500 to 100: 1, preferably from 1:50 to 10: 1, in particular from 5: 1 to 1:20.

Depending on the nature of the compound used, the weight ratio of the compound of formula (I) to the compound of formula (II) may start from 100: 1 to 1: 100, preferably from 20: 1 to 1:20, especially from 10: 1 to 1:10. Can be.

The more preferred ratio of synergistically effective amount of component (1) to component (2) is 2: 5, 1: 2, 1: 1.

A very preferred ratio of synergistically effective amount of component (1) to component (2) is 2: 5.

In the preparation of the compositions according to the invention, preference is given to using pure benzoylurea compounds of the general formula (I) and chlorfenapyr, optionally optionally further pesticidal active compounds against harmful fungi, or else herbicidal or growth-modulating activity Compounds or fertilizers can be added.

The compositions comprising the compounds of the formulas (I) and (II) according to the invention, or the simultaneous or successive use of the compounds of the formulas (I) and (II), show excellent synergism against pests from

Insects of the following necks: Insipidus (Lepidoptera), for example Agrotis ypsilon, Agrotis segetum, Alabama argillacea, Anticarcia gummatalis (Anticarsia gemmatalis), Argyresthia conjugella, Ascia monuste orseis, Autographa gamma, Bupalus piniarius, Cacosia muliana Cacoecia murinana, Capua reticulana, Caitatobia brumata, Choristoneura fumiferana, Choristoneura occidentalis, Sirpis Cirphis unipuncta, Cydia pomonella, Dendrolimus pini, Diaphania nitidalis, Diatraea g Diatraea grandiosella, Dione juno juno, Earias insulana, Elasmopalpus lignosellus, Eupoecilia ambiguella, Evetria Evetria bouliana, Feltia subterranea, Galleria mellonella, Grapolita funebrana, Grapolita molesta, Heliotis Armi Heliothis armigera, Heliothis virescens, Heliothis zea, Hellula undalis, Hibernia defoliaria, Hyphantria kunea cunea), Hyponomeuta malinellus, Keiferia lycopersicella, Lambdina fiscellaria, Lapigma excigua (Laphygma exigua), Leucoptera coffeella, Leucoptera scitella, Lithocolletis blancardella, Lobesia botrana, Loxotege stickicicalis Loxostege sticticalis, Lymanthria dispar, Lymanthria monacha, Lyonetia clerkella, Malacosoma neustria, Mamestra brassicae , Orgyia pseudotsugata, Ostrinia nubilalis, Panolis flammea, Pectinophora gossypiella, Peridroma saucia ), Phalera bucephala, Phthorimaea operculella, Phyllocnistis citrella, Pieris brassicae (Pieris brassicae), Platypena scabra, Plutella xylostella, Pseudoplusia includens, Rhyacionia frustrana, Scrovipalapula absol Scrobipalpula absoluta, Sitotroga cerealella, Sparganothis pilleriana, Spodoptera frugiperda, Spodoptera littoralis , Spodoptera litura, Thaumatopoea pityocampa, Tortrix viridana, Trichoplusia ni, rachiplusia nu , Plusia species, plusia putnami, plusia festucae, plusia oricbalcea, plusia oricbalcea (plusia oric) halcea, tuta absoluta and Zeiraphera canadensis,

Beetles (Coleoptera), for example Agrilus sinuatus, Agriotes lineatus, Agriotes obscurus, Amphimalas Solsti Amphimallus solstitialis, Anisandrus dispar, Antonomus grandis, Antonomus pomorum, Afthona euphoridae, Athos haemomor Athous haemorrhoidalis, Atomaria linearis, Blastophagus piniperda, Blitophaga undata, Bruchus rufimanus, Brucus fisorum (Bruchus pisorum), Bruchus lentis, Victiscus betulae, Cassida nebulosa, Serotoma trifurcata, Setoni Aureta (Cetonia aurata), Cethorrhynchus assimilis, Cethorrhynchus napi, Chaetocnema tibialis, Conoderus vespertinus, Cryoceris asparagi, Ctenicera subspecies, Diabrotica longicornis, Diabrotica semipunctata, Diabrotica 12-Punktata punctata, Diabrotica speciosa, Diabrotica virgifera, Epilachna varivestis, Epitrix hirtipennis, Eutrinobirus Eutinobothrus brasiliensis, Hilobius abietis, Hypera brunneipennis, Hypera postica, Ipsty Ips typographus, Lema bilineata, Lema melanopus, Leptinotarsa decemlineata, Limonius californicus, Lisolop Lysorhoptrus oryzophilus, Melanotus communis, Meligethes aeneus, Melonta hippocastani, Melonta melolota, Oelolonta melolontha Olema oryzae, Otiorrhynchus sulcatus, Otiorrhynchus ovatus, Phaedon cochleariae, Phyllobius pyri, Philotreus Phyllotreta chrysocephala, Phyllophaga species, Phyllopertha horticola, Phyllotreta nemorum, and phyllotreta triolata (Phyllotreta chrysocephala) hyllotreta striolata, Popilia japonica, Sitona lineatus and Sitophilus granaria,

Flies, mosquitoes (Diptera), for example Aedes aegypti, Aedes albopictus, Aedes vexans, Anast Anastrepha ludens, Anopheles maculipennis, Anopheles crucians, Anopheles albimanus, Anopheles gambiae, Anopheles gambiae, Anophe Anofrio free Anopheles leucosphyrus, Anopheles minimus, Anopheles quadrimaculatus, Calliphora vicina, Ceratitis capitata, Chrysomimia Chrysomya bezziana, Chrysomya hominivorax, Chrysomya macellaria, Chrysops discalis, Cree Chrysops silacea, Chrysops atlanticus, Cochliomyia hominivorax, Contarinia sorghicola, Cordillera antropopagaga (Cordylobia anthropophaga), Culicoides furens, Culex pipiens, Culex nigripalpus, Culex quinquefaciatus, Culex quinquefaciatus Culis tarsalis, Culiseta inornata, Culiseta melanura, Dacus cucurbitae, Dacus oleae, Dacia oleae Brassicae (Dasineura brassicae), Delia antique, Delia coarctata, Delia platura, Delia radicum, Dematobia hominis , Pania Canicularis a canicularis, Geomyza Tripunctata, Gasosterophilus intestinalis, Glossina morsitans, Glossina palpalis, Glossina pushfes ( Glossina fuscipes, Glossina tachinoides, Haematobia irritans, Haplodiplosis equestris, Hippelates species, Hilemia platura Hylemyia platura, Hypoderma lineata, Leptoconops torrens, Liriomyza sativae, Liriomyza trifolii, Liriomyza triidoi, liriomyza huidobrensis, liriosis Lucilia caprina, Lucilia cuprina, Lucilia sericata, Lycoria pectoralis, Mansoni Mantisonia titillanus, Mayetiola destructor, Musca domestica, Muscina stabulans, Oestrus ovis, Opomiza florum Opomyza florum, Oscinella frit, Pegomia hysocyami, Phorbia antiqua, Phorbia brassicae, Phorbia coarctata , Phlebotomus argentipes, Psorophora columbiae, Psila rosae, Psorophora discolor, Prosimulum mixtum mixtum, Rhagoletis cerasi, Rhagoletis pomonella, Sarcophaga haemorrhoidalis, Sarcophaga species, Simulium vittum atum, Stomoxys calcitrans, Tabanus bovinus, Tabanus atratus, Tabanus lineola, and Tabanus similis ), Tipula oleracea, and Tipula paludosa,

Larvae (Thysanoptera), for example, Dichromothrips corbetti, Dichromothrips subspecies, Frankliniella fusca, Franklini Frankliniella occidentalis, Frankliniella tritici, Scirtothrips citri, Tripps oryzae, Tripps palmi and Tripps Statabis (Thrips tabaci),

Termites (Isoptera), for example Carlotermes flavicollis, Leucotermes flavipes, Heterotermes aureus, Reticulite termes Reticulitermes flavipes, Reticulitermes virginicus, Reticulitermes lucifugus, Termes natalensis and Coptotermes formosanus formosanus),

Wheels (Blattaria-Blattodea), for example Blatella germanica, Blatella asahinae, Periplaneta americana, Perry Peretaplaneta japonica, Periplaneta brunnea, Periplaneta fuligginosa, Periplaneta australasiae and Blata orientalis,

Hemiptera (Hemiptera), for example Acrosternum hilare, Blissus leucopterus, Cytopeltis notatus, Disdercus singh Dydercus cingulatus, Dysdercus intermedius, Eurygaster integriceps, Euschistus impictiventris, Leptoglossus phylpusyl phylus ), Lygus lineolaris, Lygus pratensis, Nezara viridula, Piesma quadrata, Solubea insularis , Thianta perditor, Acyrthosiphon onobrychis, Adelges laricis, Aphidula nasturtii, Apis fabae, Aphis Apis forbesi, Apis pomi, Apis gossypii, Apis grossulariae, Apis schneideri, Apis spiraecola , Apis sambuci, Acyrthosiphon pisum, Aulacorthum solani, Bemisia argentifolii, Bemisia tabaci, Brachycau Brachycaudus cardui, Brachycaudus helichrysi, Brachycaudus persicae, Brachycaudus prunicola, Brevicoryne brassicane brass , Capitophorus horni, Cerosipha gossypii, Chaetosiphon fragaefolii, Cryptomyzus ribis, de Dreyfusia nordmannianae, Dreyfusia piceae, Dysaphis radicola, Dysaulacorthum pseudosolani, Dysapisflagflass Tysaphis plantaginea, Dysaphis pyri, Empoasca fabae, Hyopteropterus pruni, Hyperomyzus lactucae, Macromoy ave Nasi (Macrosiphum avenae), Macrosis uphorbiae (Macrosiphum euphorbiae), Macrosiphon rosae, Megoura viciae, Melanaphis pyrarius, Metopopium pyromrius (Metopolophium dirhodum), Myzus persicae, Myzus ascalonicus, Myzus cerasi, Myzus varians, Nasonovia Libis-ni Gri (Nasonovia ribis-ni gri, Nilaparvata lugens, Pemphigus bursarius, Perkinsiella saccharicida, Phorodon humuli, Psylla mali ), Psylla piri, Rhopalomyzus ascalonicus, Rhopalosiphum maidis, Rhopalosiphum padi, Rhopalosiphum padi, Rhopalosiphum insertum ), Sappaphis mala, Sappaphis mali, Schizaphis graminum, Schizoneura lanuginosa, Sitobion avenae, Trialeurodes vaporariorum, Toxoptera aurantii, Viteus vitifolii, Cimex lectularius, Cimex hemipterus ), Redobie Enyl-less switch (Reduvius senilis), yttria Thomas (Triatoma) species, and aryl loose Cri tattoo's (Arilus critatus),

Ants, bees, wasps, leaf bees (Hymenoptera), for example Athalia rosae, Atta cephalotes, Atta capiguara, Atta Atta cephalotes, Atta laevigata, Atta robusta, Atta sexdens, Atta texana, Crematogaster species, Hoplocampa minuta, Hoplocampa testudinea, Monomorium pharaonis, Solenopsis geminata, Solenopsis invicta, Solenopsis richteri, Solenopsis xyloni, Pogonomyrmex barbatus, Pogonomyrmex californicus, Pedolome megacepala (Pheidole megacephala), Dashimutila oxy Talismutilla occidentalis, Bombus species, Vespula squamosa, Parabespura vulgaris, Paravespura pennsylvanica, Paravesula germana Paravespula germanica, Dolichovespula maculata, Vespa crabro, Polistes rubiginosa, Camponotus florinos and Lineepitema humilies Linepithema humile),

Crickets, vultures, locusts (Orthoptera), for example Acheta domestica, Gryllotalpa gryllotalpa, Locusta migratoria , Melanoplus bivittatus, Melanoplus femurrubrum, Melanoplus mexicanus, Melanoplus sanguinipes, Melanoflux Spreadus Melanoplus spretus, Nomadacris septemfasciata, Schistocerca americana, Schistocerca gregaria, Dociostaurus maroccanus, Tachycines asynamorus, Oedaleus senegalensis, Zonozerus variegatus, Hieroglyphus Hiraglyphus daganensis, Kraussaria angulifera, Calliptamus italicus, Cortoicetes terminifera and Locustana pardalina ,

Arachnids such as templates (Acarina), for example the following families: Argasidae, Ixodidae and Sarcoptidae, such as Ambliooma Americanum (Amblyomma americanum), Amblyomma variegatum, Ambryomma maculatum, Argas persicus, Bophylus annulatus, Buffulus deulatus Boophilus decoloratus, Boophilus microplus, Dermacentor silvarum, Dermacentor andersoni, Dermacentor variabilis, Hyaloma truncatum, Ixodes ricinus, Ixodes rubicundus, Ixodes scapularis, Ixodes holocyclus, Ixodes paro Cypicus (I xodes pacificus, Ornithodorus moubata, Ornithodorus hermsi, Ornithodorus turicata, Ornithonyussus bacoti, Orbius Megini megnini, Dermanyssus gallinae, Psoroptes ovis, Rhipicephalus sanguineus, Rhipicephalus appendiculatus, Rippicephalus Evert (Rhipicephalus evertsi), Sarcoptes scabiei, and Eriophyidae species, such as Aculus schlechtendali, Phyllocoptruta oleivora and Eriopidae (Eriophyes sheldoni); Tarsonemidae species such as Phytonemus pallidus and Polyphagotarsonemus latus; Tenuipalpidae species, such as, for example, Brevipalpus phoenicis; Tetranychidae species such as Tetranychus cinnabarinus, Tetranychus kanzawai, Tetranychus pacificus, Tetranychus telarius ) And Tetranychus urticae, Panonicus ulmi, Panonicus citri, and Oligonychus pratensis; Araneida, for example Latrodectus mactans and Loxosceles reclusa, mites (Ixodida), for example Pipicephalus sangineus (Phipicephalus sanguineus), or mites, such as Mesostigmata, for example Ornithonyssus bacoti and Deermanyssus gallinae, Prostigmata, for example Pimo Pymotes tritici, or Astigmata, for example Acarus siro, or additional mites, such as Polyphagotarsonemus latus, Philococcutta Phyllocoptruta oleivora, Eutetranychus banksi, Aculops lycopersici, Tenuipalpus hevea, Eriopies cuereroni (Eriophyes querreronis),

Fleas (Siphonaptera), for example, Ctenocephalides felis, Ctenocephalides canis, Xenopsylla cheopis, Fulex italans Pulex irritans, Tunga penetrans and Nosopsyllus fasciatus,

Worms, zebras (Thysanura), for example Lepisma saccharina and Thermobia domestica,

Centipedes (Chilopoda), for example Scutigera coleoptrata,

Polypods (Diplopoda), for example Narrceus species,

Insects (Dermaptera), for example Forficula auricularia,

Advection (Phthiraptera), for example, Pediculus humanus capitis, Pediculus humanus corporis, Pthirus pubis, Haemato Pinus uesterus (Haematopinus eurysternus), Haematopinus suis, Linognathus vituli, Bovicola bovis, Menopon gallinae, Menakan Menacanthus stramineus and Solenopotes capillatus,

Plant parasitic nematodes, such as root-knot nematodes, meloidogyne arenaria, meloidogyne chitwoodi, meloidogyne exigua, meloidogyne hapla, meloydogyne hapla Melidogyne incognita, Meloidogyne javanica and other Meloidogine species; Cyst nematodes, Globoderra rostochiensis, Globodera pallida, Globodera tabacum and other globodera species; Heterodera avenae, Heterodera glycines, Heterodera schachtii, Heterodera trifolii, and other heterodera species; Heterodera avenae, Heterodera glycines, Heterodera schachtii, Heterodera trifolii, and other heterodera species; Seed lump nematodes, anguina funesta, anguina tritici and other eye or species; Stem and leaf nematodes, Aphelenchoides besseyi, Aphelenchoides fragariae, Apelenchoides ritzemabosi, and other Apelenchoides species; Salivary nematodes, Belonolaimus longicaudatus and other Belonolimus species; Pine nematodes, Bursaphelenchus xylophilus and other Bursapelencus species; Ring nematodes, Criconema species, Criconemella species, Criconemoides species, and Mesocriconema species; Stem and bulb nematodes, Ditylenchus destructor, Ditylenchus dipsaci, Ditylenchus myceliophagus and other Ditylencus species; Awl nematodes, Dolichodorus species; Helix nematodes, Helicotylenechus dihystera, Helicotylenechus multicinctus, and other Helicotylenecus species; Rotilenchus Rotylenchus robustus and other Rotilenkus species; Foliar nematodes, Hemicycliophora species and Hemicriconemoides species; Hirshmanniella species; Harpoon nematodes, Hoplolaimus columbus, Hoplolaimus galeatus and other Hopolaimus species; False root-knot nematodes, Nacobbus aberrans and other Nacobus species; Needle nematodes, Longongorus elongatus and other long-airway rhusi; Salivary nematodes, Paratylenchus species; Root nematodes, Pratylenkus brachyurus, Pratylenkus coffeae, Pratylenkus curvitatus, Pratylenkus goey (Pratylenchus goodeyi) Prattylenchus neglectus, Pratylenkus penetrans, Pratylenkus scribneri, Pratylenkus vulnus, Pratylenkus zeae and Prattylenchus zeae Other pratylenkus species; Radinaphelenchus cocophilus and other Radina pelencus species; Perforated nematodes, Radopholus similis and other Radopolus species; Dragonfly nematodes, Rotylenchulus reniformis and other Rotylenculus species; Scutellonema species; Blunt root nematodes, Trichodorus primitivus and other Trichodorus species; Paratrichodorus minor and other Paratrichodorus species; Atrophic nematodes, Tylenchorhynchus claytoni, Tylenchorhynchus dubius and other Tylenchorhynchus species and Merlinius species; Nematodes, Tylenchulus semipenetrans and other Tylenculus species; Gum nematodes, Xiphinema americanum, Xiphinema index, Xiphinema diversicaudatum and other Xypinema species; And other plant parasitic nematode species.

In a very preferred embodiment, the insect is selected from leaf insect pests.

One embodiment of the present invention relates to a method for combating or controlling leaf insects selected from Repidoterra neck. Within this embodiment, insects from the chestnut moth, in particular insects selected from the group consisting of Alabama argillacea, anticarsia gummatalis, heliotis nonresense, Pseudoflusia influence and Spodoptera pruperferda, are preferred. Do. White butterfly (especially Asian Monuste orcese as a target), four-footed butterfly (especially Dion Juno Juno as a target), horned moth (especially Ptorimaeea opulculera and tuta Absoluta as a target) and zombie moth Further preferred are insects selected from the family consisting of (particularly flutella xyclestella as targets).

A further embodiment of the present invention relates to a method for combating or controlling insects, particularly leaf insects selected from blind stink bugs, aphids and flours.

A further embodiment of the present invention relates to a method of combating or controlling leaf insects selected from the hemiphterra neck.

A further embodiment of the present invention relates to a method for combating or controlling leaf insects selected from the extinct species (Delphacidae) and the cicada worm (Deltocephalidae). Among the extinct species, the larvae (Laodelphax striatellus), the rice plant (Nilaparvata Rugens) and the white larvae (Sogatella furcifera) are preferred target insects. Among the cicada larvae, cicada larvae (Nephotettix cincticeps, Nephotettix nigropictus and Nephotettix virescens) are preferred target insects.

A further embodiment of the invention combats or controls leaf insects selected from Diphthera heads, more preferably fruit flies (in particular Ceratitis capitata as a target) and oyster flies (in particular, Liriomiza fuidobransis as a target). It is about how to.

A further embodiment of the present invention relates to a method of combating or controlling leaf insects selected from beetles from Cleopatra throat. Within this embodiment, insects from the Lepidoptera are preferred, in particular Diabrotica Specciosa as targets.

A further embodiment of the present invention relates to a method of combating or controlling leaf insects selected from the moths from the tisanophthera neck. Within this embodiment preference is given to insects from the coleopteran family, in particular Tryps Tabashi as targets.

A further embodiment of the present invention relates to a method of combating or controlling leaf insects selected from seminude from Hemiftera neck. Within this embodiment, insects from the Gariaceae (especially Bemisia Tabashi as targets) and aphids (in particular Brevicorine brassicae as targets) are preferred.

A further embodiment of the present invention relates to a method for combating or controlling leaf insects selected from the tree Trombidiformes. Within this embodiment, insects from the mite, in particular Brevipalpus poenisis as targets, are preferred.

A further embodiment of the invention relates to a method for combating or controlling mites selected from the tromvidodiformes throat. Within these embodiments, leaf mites (particularly tetranicus urticae and panonicus woolen as targets), dust mites (particularly polypagotarsonemus ratus as targets) and gallaceae (particularly as targets) Malignant) is preferred.

The compositions according to the invention control the target pests and / or ground parts of agricultural plants, seeds, roots and / or arable land, food, plantations, greenhouses, orchards or vineyard crops, ornamental trees, planted trees or forests and / or interests. Used to protect plants, including any plant (s) present.

Certain embodiments of the present invention treat and / or treat a plant from attack or infestation by insects, mites or nematodes, comprising applying the composition according to the invention to a plant or soil or water in which the plant is growing. Or a method of protection. Preferably the composition is applied to agricultural plants.

The term “agricultural plant” means a portion or a portion thereof (e.g., a seed) or the whole is harvested or grown on a commercial scale, or feed, food, fiber (e.g., cotton, linen), chemical treatment (oil, sugar) Is understood to be a plant that serves as an important source of combustibles (eg wood, bioethanol, biodiesel, biomass) or other chemical compounds. Agricultural plants may also include horticultural plants, ie plants that grow in gardens (not arable land), such as certain fruits, vegetables, and flowers (eg, roses). Preferred agricultural plants are for example cereals such as wheat, rye, barley, rye, oats, sorghum or rice, beets, for example beets or feed beets; Fruits, such as fruit, nuclear or berry, such as apples, melons, watermelons, papayas, passion fruit, pears, plums, peaches, almonds, cherries, strawberries, raspberries, blackberries or gooseberries; Leguminous plants, such as drybean, lentils, peas, alfalfa or soybeans; Oil plants, such as rapeseeds, oilseed rape, canola, linseed, mustard, olives, sunflowers, coconuts, cocoa seeds, castor oil plants, oil palms, peanuts or soybeans; Cucurbits such as squash, cucumbers or melons; Textile plants such as cotton, flax, hemp or jute; Fruits such as oranges, lemons, grapefruit or mandarins; Vegetables such as spinach, lettuce, asparagus, cabbage, carrots, onions, tomatoes, potatoes, gourds or paprika; Camphor plants such as avocado, cinnamon or camphor; Energy and raw plants such as corn, soybeans, rape, canola (oilseed rape), sugarcane or oil palms, corn, tobacco, nuts, coffee, tea trees, bananas, vines such as raw grapes, grape vines for grape juice Or pepper, hops, grass, natural rubber plants or ornamental and forest plants such as flowers, shrubs, hardwoods or evergreens (eg conifers) and plant propagation materials such as seeds and crop materials of these plants.

In the context of the present invention, the term "plant" refers to an entire plant, part of a plant or plant propagation material such as seeds, seed pieces, transplants, seedlings or cuttings.

Particular embodiments relate to methods of treating and / or protecting agricultural plants selected from lost plants, potatoes, rice, cereals, soybeans, dry beans, cotton, vegetables, sugar cane, and horticultural plants. The lost plants of the present invention are the main types of fruits, such as berries, such as grapes, blueberries; Nuclear fruits such as peaches, cherries, olives, plums and walnuts; Fruits and vegetables such as blackberries and raspberries; Complex fruits such as pineapple, figs and mulberry; And stomach fruits, such as apples, pears and strawberries, and citrus fruits such as oranges, grapefruit, kumquats, lemons, limes, tangerines, temples, citranges, tangelos, pomelos and citrons.

Plants treated with the composition according to the invention are all genetically modified or transgenic plants, for example crops resistant to the action of herbicides or fungicides or insecticides due to breeding methods including genetic engineering methods, or examples For example, plants having modified properties compared to existing plants, which may be produced by conventional breeding methods and / or by the production of mutants or by recombinant methods.

Some of the compositions according to the invention have systemic action and thus can be used for the protection of plant shoots against leaf pests, as well as for the treatment of seeds and roots against soil pests. The term “seed treatment” includes all suitable seed treatment techniques known in the art, such as seed dressings, seed coatings, seed meal, seed soaking and seed pelleting.

In particular, the seeds are tuber and caliber vegetables, such as arachacha, aroroot, artichoke, canna, cassava, carrots, chayote roots, chupa, tarotoran, ginger, leren, onions, potatoes, radishes, tinners, turmeric, yam beans , E; Leafy vegetables such as amaranth, arugula, cardoon, celery, celtus, cheville, chrysanthemum, cres, dandelion, dock, endive, fennel, kale, leek, lettuce, oritz, parsley, perslin, radi Fuck, rubab, spinach, chard, color amaranth, zinnia and stem cabbage plants such as broccoli, brussels sprouts, cabbage, cauliflower, cabalo broccoli, curly kale, cola; Multileaf cabbage plants such as broccoli lav, cabbage, collard, kale, rice bran, mustard leaves, mustard spinach, rapeseed leaves; Fruit vegetables such as soybeans, chili, post-harvest, eggplant, cherry, pepino, peas, pepper, tomatillo, tomato. It is preferred that the seeds are broccoli, carrots, cabbage, in particular cabbage, red cabbage, savoy cabbage, white cabbage, celery, cauliflower, cola and radish seeds.

Preferred embodiments of the present invention are directed to a method of protecting or treating cotton from pest Alabama argillacea or tetranicus urticae, comprising applying composition A to cotton plants.

A preferred embodiment of the present invention is directed to a method of protecting or treating a citrus plant from pests Brevipalpus poenisis, phycocoptera oleivora and polypago tarsonemus latus, comprising applying composition A to citrus plants. It is about.

Preferred embodiments of the present invention are directed to a method of protecting or treating a coffee plant from pest Brevipalpus poenisis comprising applying composition A to a coffee plant.

Preferred embodiments of the present invention are directed to a method of protecting or treating an apple plant from pest panonicus wool, which comprises applying composition A to an apple plant.

Preferred embodiments of the present invention comprise soybean plants from pest anticarsia gemmatalis, pseudoflusia influenzae, tetranicus urticae and polypagotarsoneus latus, comprising applying composition A to soybean plants. It relates to a method of protecting or processing.

Preferred embodiments of the invention relate to a method of protecting or treating onion plants from pest tryptabasi, comprising applying composition A to onion plants.

Preferred embodiments of the present invention comprise potato plants from the pest Diabrotica specosa, Liriomiza fuidobrense, Ptorimaeea operculera and Tryps Tabashi, comprising applying Composition A to potato plants. It relates to a method of protecting or processing.

Preferred embodiments of the present invention are directed to a method of protecting cabbage plants from pests, such as Asia Monuste orces, Liriomiza fuidobrences, comprising applying Composition A to cabbage plants.

Preferred embodiments of the present invention are directed to methods of protecting or treating chrysanthemum plants from pest tryps tabasi and tetranicus urticae, comprising applying composition A to chrysanthemum plants.

Preferred embodiments of the present invention protect drybean plants from pest Diabrotica specosa, Tryps Tabashi, Tetranicus Urticae and Bemisia Tabashi, comprising applying Composition A to drybin plants. Or a method of treatment.

A preferred embodiment of the present invention relates to a method for protecting or treating papaya plants from pest polypago tarsonemus ratus, comprising applying composition A to papaya plants.

Preferred embodiments of the present invention are directed to a method of protecting or treating a Passionfruit plant from the pest Dion Juno Juno comprising applying Composition A to the Passionfruit plant.

Preferred embodiments of the present invention are directed to a method for protecting or treating a melon or watermelon plant from pest tryptabasi, comprising applying composition A to the melon or watermelon plant.

Preferred embodiments of the present invention are directed to a method of protecting or treating a corn plant from the pest Spodoptera pruperiferda, comprising applying composition A to the corn plant.

Preferred embodiments of the present invention are directed to a method of protecting or treating a pepper plant from pest Diabrotica specosa, comprising applying composition A to the pepper plant.

Preferred embodiments of the present invention are directed to a method of protecting or treating a rose plant from pest tetranicus urticae, comprising applying composition A to the rose plant.

Preferred embodiments of the present invention are directed to a method of protecting or treating tomato plants from pests Akulops lycopesesi, tetranikus urticae and tuta absoluta, comprising applying composition A to tomato plants.

For the use according to the invention, the compositions or combinations of the active compounds I and II can be converted into conventional preparations, for example solutions, emulsions, suspensions, dusts, powders, pastes and granules. The form of use depends on the specific purpose for which it is intended; In each case, a fine and uniform distribution of the compound according to the invention should be ensured.

A preferred embodiment is a method of foliar application of the composition according to the invention. As used herein, the term "foliar application" means applying the composition to plant leaves via a spray device. Foliar application is possible at all stages after plant sprouting.

The formulations are prepared in a known manner, for example by extending the active compound with solvents and / or carriers and, if desired, using emulsifiers and dispersants. Suitable solvents / adjuvant are essentially as follows:

Water, aromatic solvents (eg Solvesso products, xylenes), paraffins (eg mineral oil fractions), alcohols (eg methanol, butanol, pentanol, benzyl alcohol), ketones (eg For example, cyclohexanone, gamma-butyrolactone), pyrrolidone (NMP, NOP), acetate (glycol diacetate), glycols, fatty acid dimethylamides, fatty acids and fatty acid esters (in principle, solvent mixtures may also be used. has exist),

Carriers such as ground natural minerals (eg kaolin, clay, talc, chalk) and ground synthetic minerals (eg highly dispersed silica, silicates); Emulsifiers such as nonionic and anionic emulsifiers (eg, polyoxyethylene fatty alcohol ethers, alkylsulfonates and arylsulfonates) and dispersants such as lignosulphite waste liquors and methylcellulose.

Suitable surfactants include lignosulfonic acid, naphthalenesulfonic acid, phenolsulfonic acid, alkali metals of alkaline metals of dibutylnaphthalenesulfonic acid, alkaline earth metals and ammonium salts, alkylarylsulfonates, alkyl sulfates, alkylsulfonates, fatty alcohol sulfates, fatty acids and sulfated fats. Alcohol glycol ethers, also condensates of sulfonated naphthalene and naphthalene derivatives with formaldehyde, condensates of naphthalene or naphthalenesulfonic acid with phenols and formaldehyde, polyoxyethylene octylphenol ethers, ethoxylated isooctylphenols, octylphenols, nonylphenols, Alkylphenol polyglycol ethers, tributylphenyl polyglycol ethers, tristearylphenyl polyglycol ethers, alkylaryl polyether alcohols, alcohols and fatty alcohols ethylene oxide condensates, ethoxylated castor oils, polyoxyethylene alkyl ethers, ethoxylated Polyoxypropylene, Lauryl Alcohol Polygly Ether acetal, sorbitol esters, the league nosul sulfite waste liquid, and methylcellulose.

Medium to high boiling mineral oil fractions such as kerosene or diesel oils, in addition to coal tar oils and oils of vegetable or animal origin, aliphatic, cyclic and aromatics for the preparation of direct sprayable solutions, emulsions, pastes or oil dispersions Hydrocarbons such as toluene, xylene, paraffin, tetrahydronaphthalene, alkylated naphthalene or derivatives thereof, methanol, ethanol, propanol, butanol, cyclohexanol, cyclohexanone, isophorone, strong polar solvents such as dimethyl sulfoxide , N-methylpyrrolidone and water are suitable.

In addition, cryoprotectants such as glycerin, ethylene glycol, propylene glycol and bactericides may be added to the formulation.

Suitable antifoams are, for example, antifoams based on silicon stearate or magnesium stearate.

Suitable preservatives are, for example, dichlorophene and benzyl alcohol hemiformal.

Seed treatment formulations may further comprise binders and optionally colorants.

A binder can be added to improve the binding of the active material to the seed after treatment. Suitable binders are polyvinylalcohols, polyvinylpyrrolidones, polyacrylates, polymethacrylates, polybutenes, polyisobutylenes, polystyrenes, polyethyleneamines, polyethyleneamides, polyethyleneimines as well as block copolymer EO / PO surfactants. (Lupasol®, Polymin®), polyethers, polyurethanes, polyvinylacetates, tylos, and copolymers derived from these polymers.

Optionally, colorants may also be included in the formulation. Suitable colorants or dyes for seed treatment formulations include Rhodamin B, C.I. Pigment Red 112, C.I. Solvent Red 1, Pigment Blue 15: 4, Pigment Blue 15: 3, Pigment Blue 15: 2, Pigment Blue 15: 1, Pigment Blue 80, Pigment Yellow 1, Pigment Yellow 13, Pigment Red 112, Pigment Red 48: 2, Pigment Red 48: 1, Pigment Red 57: 1, Pigment Red 53: 1, Pigment Orange 43, Pigment Orange 34, Pigment Orange 5, Pigment Green 36, Pigment Green 7, Pigment White 6, Pigment Brown 25, Basic Violet 10, Basic Violet 49, Acid Red 51, Acid Red 52, Acid Red 14, Acid Blue 9, Acid Yellow 23, Basic Red 10, Basic Red 108.

An example of a gelling agent is carrageen (Satiagel ^® ).

Powders, sparger materials and powdered products can be prepared by mixing or entraining the active material with a solid carrier.

Granules such as coated granules, impregnated granules and homogeneous granules can be prepared by binding the active compound to a solid carrier. Examples of solid carriers are inorganic earths such as silica gel, silicates, talc, kaolin, atacclay, limestone, lime, chalk, church clay, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic Materials, fertilizers such as, for example, ammonium sulphate, ammonium phosphate, ammonium nitrate, urea, and products of vegetable origin such as flour, wood meal, wood meal and nut meal, cellulose powder and other solid carriers.

In general, the formulations comprise 0.01 to 95% by weight, preferably 0.1 to 90% by weight of active compound. The active compound is used in purity (according to the NMR spectrum) of 90% to 100%, preferably 95% to 100%.

For seed treatment purposes, each formulation may be diluted 2 to 10 times so that the concentration of active compound in the ready-to-use formulation may reach 0.01 to 60% by weight, preferably 0.1 to 40% by weight.

The following is an example of a formulation:

1.Product for Dilution with Water

For seed treatment purposes, these products can be applied to the seed with or without dilution.

A) Aqueous concentrates (SL, LS)

10 parts by weight of the active compound are dissolved in 90 parts by weight of water or an aqueous solvent. Alternatively, wetting agents or other auxiliaries are added. Dilution with water causes the active compound to dissolve. In this way, a formulation having an active compound content of 10% by weight is obtained.

B) Dispersible Concentrates (DC)

20 parts by weight of the active compound are dissolved in 70 parts by weight of cyclohexanone with addition of 10 parts by weight of dispersant, for example polyvinylpyrrolidone. Dilution with water gives a dispersion. The active compound content is 20% by weight.

C) emulsifiable concentrate (EC)

15 parts by weight of active compound are dissolved in 75 parts by weight of xylene with the addition of calcium dodecylbenzenesulfonate and castor oil ethoxylate (5 parts by weight in each case). Dilution with water gives an emulsion. The active compound content of the formulation is 15% by weight.

D) Emulsions (EW, EO, ES)

25 parts by weight of active compound are dissolved in 35 parts by weight of xylene with the addition of calcium dodecylbenzenesulfonate and castor oil ethoxylate (in each case 5 parts by weight). This mixture is added to 30 parts by weight of water and made into a homogeneous emulsion using an emulsifier (eg Ultraturrax). Dilution with water gives an emulsion. The active compound content of the formulation is 25% by weight.

E) Suspension (SC, OD, FS)

In a stirred ball mill, 20 parts by weight of the active compound are ground with the addition of 10 parts by weight of dispersant and wetting agent and 70 parts by weight of water or organic solvent to obtain a fine active compound suspension. Dilution with water gives a stable suspension of the active compound. The active compound content of the formulation is 20% by weight.

F) Water Dispersible Granules and Water Soluble Granules (WG, SG)

50 parts by weight of active compound are finely divided by addition of 50 parts by weight of dispersant and wetting agent and prepared into water dispersible or water soluble granules using technical equipment (eg extrusion, spray tower, fluidized bed). Dilution with water gives a stable dispersion or solution of the active compound. The active compound content of the formulation is 50% by weight.

G) Water-dispersible powders and water-soluble powders (WP, SP, SS, WS)

75 parts by weight of active compound are ground in a rotor-stator mill with addition of 25 parts by weight of dispersant and wetting agent as well as silica gel. Dilution with water gives a stable dispersion or solution of the active compound. The active compound content of the formulation is 75% by weight.

H) Gel Formulation (GF)

In a ball mill, 20 parts by weight of active compound, 10 parts by weight of dispersant, 1 part by weight of gelling agent and 70 parts by weight of water or organic solvent are ground to provide a fine suspension. Dilution with water gives a stable suspension with an active compound content of 20% by weight.

2. Products applied without dilution

I) Germinated powder (DP, DS)

5 parts by weight of the active compound are ground finely and mixed intimately with 95 parts by weight of finely divided kaolin. This gives a dustable product having an active compound content of 5% by weight.

J) granules (GR, FG, GG, MG)

0.5 parts by weight of active compound is ground and associated with 99.5 parts by weight of carrier. The process uses extrusion, spray-drying or fluidized beds. This gives granules to be applied undiluted with an active compound content of 0.5% by weight.

K) ULV solution (UL)

10 parts by weight of the active compound are dissolved in 90 parts by weight of an organic solvent, for example xylene. This gives a product which is applied without dilution with an active compound content of 10% by weight.

For seed treatment, water soluble concentrates (LS), suspensions (FS), powdered powders (DS), water dispersible and water soluble powders (WS, SS), emulsions (ES), emulsifiable concentrates (EC) and gel preparations (GF) is used. Such formulations may be applied to the seed in undiluted form, or preferably in diluted form. Application can be carried out before sowing.

In a preferred embodiment, the FS formulation is used for seed treatment. Typically, FS formulations contain 1 to 800 g / l active ingredient, 1 to 200 g / l surfactant, 0 to 200 g / l cryoprotectant, 0 to 400 g / l binder, 0 to 200 g / l l pigment and up to 1 liter of solvent, preferably water.

The active compounds are themselves, in the form of their preparations, or in the forms of use prepared therefrom, for example directly sprayable solutions, powders, suspensions or dispersions, emulsions, oil dispersions, pastes, powdery products, sparging substances or granules In the form, it can be used by spraying, spraying, powdering, spraying or injecting. The form of use depends entirely on the intended purpose; In each case it is intended to ensure the finest possible distribution of the active compounds according to the invention.

Aqueous use forms can be prepared from emulsion concentrates, pastes or wettable powders (sprayable powders, oil dispersions) by adding water. In order to prepare emulsions, pastes or oil dispersions, the material as such or a material dissolved in oil or solvent can be homogenized in water by wetting agents, tackifiers, dispersants or emulsifiers. Alternatively, concentrates consisting of the active substances, wetting agents, tackifiers, dispersants or emulsifiers and, where appropriate, solvents or oils can be prepared, which concentrate is suitable for dilution with water.

Active compound concentrations in ready-to-use formulations can vary within a relatively wide range. In general, they are 0.0001 to 10%, preferably 0.01 to 1%.

The active compounds can also be used successfully in ultra low volume processes (ULV), which makes it possible to apply formulations comprising more than 95% by weight of active compounds, or even to apply the active compounds without additives.

Various types of oils, wetting agents, adjuvants, herbicides, fungicides, other insecticides, or bactericides can be added to the active compound and, if appropriate, added just prior to use (tank mix). These agents may be mixed with the agents according to the invention in a weight ratio of 1: 100 to 100: 1, preferably 1:10 to 10: 1.

The compositions of the present invention may also contain other active ingredients, such as other insecticides (which may be insecticides, fungicides, herbicides), fertilizers such as ammonium nitrate, urea, kali, and superphosphates, phytotoxics and plant growth regulators , Emollients and nematicides. These additional ingredients may be used in combination or sequentially with the compositions described above and, where appropriate, added only immediately prior to use (tank mix). These agents can be mixed with the mixtures according to the invention in a weight ratio of 1:10 to 10: 1. For example, the plant (s) may be sprayed with a composition of the invention before or after treatment with other active ingredients.

The compositions and methods according to the invention are particularly useful for controlling pests. The compositions and methods according to the invention are particularly useful for combating animal pests.

Methods of controlling and / or combating animal pests include, but are not limited to, animal pests, their habitat, breeding grounds, food sources, cultivated plants, seeds, soil, areas, materials or environments in which animal pests are or may be grown, or from animal attack or invasion. Treating, ie, contacting a substance, plant seed, soil, surface or space to be protected with a pesticidal effective amount of a mixture of one or more active compounds of formula (I) and one or more active compounds of formula (II).

The pesticidal composition according to the invention is suitable for the efficient control of invertebrate pests, in particular insects, ticks and nematodes. They can be applied to any stage of development and all stages of development such as eggs, larvae, pupa and adults.

Pests can be controlled by contacting the pests themselves, their food sources, their habitats, their breeding grounds or their growing places with a pesticide effective amount of a mixture of the present invention or a composition comprising active compounds I and II.

"Dwelling place" means a plant, seed, soil, area, substance or environment in which a pest is growing or can be grown.

In general, an “insect effective amount” is a pattern necessary to achieve a discernible effect on growth, including the effect of necrosis, killing, delaying, preventing, and eliminating, destroying, or otherwise reducing the occurrence and activity of the target organism. By the amount of the composition comprising the active compound according to the invention. The pesticidal effective amount may vary depending on the various mixtures / compositions used in the present invention. The pesticidal effective amount of the mixture / composition will also vary according to the prevailing conditions such as the desired pesticidal effect and duration, climate, target species, native location, mode of application, and the like.

Whenever used in the context, the term pesticidal effective amount according to the invention always refers to a synergistically effective amount of compounds I and II.

From the above, it will be appreciated that compounds I and II may be applied simultaneously, ie jointly (eg in the same formulation) or separately (eg in different formulations, eg in the form of a kit), or sequentially. . It will also be appreciated that when applied sequentially, the compounds I and II that are applied sequentially should be applied within a period of time to allow the subject to achieve or optimize the above-mentioned beneficial synergistic effects on the subject (eg, pest, plant or animal). will be.

Compounds I and II are usually 20: 1 to 1:50, in particular 10: 1 to 1:10, especially 1: 5 to 1: 1, particularly preferably 1: 5 to 1: 3, and also preferably In a weight ratio of 1: 3 to 1: 2, mainly 1: 5, or 1: 4, or 1: 3, or 2: 5, or 1: 2, or 2: 4, or 3: 5, or 4: 5 Or in a weight ratio of 1: 1. Very particularly, the weight ratios of compounds I and II are each approximately 2: 5.

According to a preferred effect, the application rate of the mixture according to the invention is 1 to 2500 g / ha, preferably 5 to 2000 g / ha, more preferably 50 to 1500 g / ha, especially 50 to 750 g / ha, more More particularly 5 to 500 g / ha.

The composition according to the invention is also suitable for the protection of seed and seedling roots and shoots against soil pests.

Conventional seed treatment formulations include, for example, fluid concentrate FS, solution LS, dry treatment powder DS, water dispersible powder WS or granules for slurry treatment, water soluble powder SS and emulsion ES. Application to seeds is carried out before sowing, directly on the seeds or after pre-germination, at sowing or after sowing. FS formulations are preferred.

In the treatment of seeds, the application amount of the mixture of the invention is generally from 0.1 g to 10 kg per 100 kg of seeds, in particular from 1 g to 2 kg per 100 kg of seeds. Individual or co-application of compounds I and II, or application of mixtures of compounds I and II, is carried out by spraying or spraying seeds, seedlings, plants or soil before or after planting or before or after plant sprouting.

The invention also provides a composition as defined above, or a composition further comprising an additional active ingredient in a compound of formulas (I) and (II), or two or more compositions each providing one of the active ingredients of formulas (I) and (II). A propagation product, in particular a seed, of a plant comprising a mixture, ie coated with and / or containing it. Seeds comprise the mixture of the present invention in an amount of 0.1 g to 10 kg per 100 kg of seeds, preferably 1 g to 5 kg per 100 kg and most preferably 1 g to 2.5 kg per 100 kg.

The compositions of the present invention are effective through both contact (contact via soil, glass, wall, bed mosquito net, carpet, plant part or animal part) and ingestion (bait, or plant part), and nutrient exchange and delivery.

The composition according to the invention is preferably effective via leaf contact for the protection of the plant.

According to a further embodiment of the invention, the pesticidal composition is used through soil application. Soil applications are particularly preferred for use against ants, termites, flies, crickets, grubs, root weevils, root beetles or nematodes.

According to another embodiment of the invention, for use against non-crop pests such as ants, termites, wasps, flies, mosquitoes, crickets, grasshoppers or cockroaches, the compositions of the invention It is prepared as a bait formulation.

The bait may be a liquid, solid or semi-solid preparation (e. G., A gel). Bait used in the composition is a product that is sufficiently attractive to stimulate insects such as ants, termites, wasps, flies, mosquitoes, crickets, etc. or cockroaches to ingest it. The attractant may be selected from ingestion stimulants or para and / or sex pheromones. Suitable ingestion stimulants are, for example, from animal and / or plant proteins (meat, fish meal or blood meal, insect parts, cricket powder, egg yolk), fats and oils of animal and / or plant origin, or mono-, oligo- or poly Organosaccharides, in particular sucrose, lactose, fructose, dextrose, glucose, starch, pectin or even molasses or honey, or salts such as ammonium sulfate, ammonium carbonate or ammonium acetate. Fresh or decaying portions of fruits, crops, plants, animals, insects, or certain parts thereof may also act as uptake stimulants. Pheromones are known to be more insect specific. Specific pheromones are described in the literature and are known to those skilled in the art.

Formulations of pesticidal compositions according to the invention as aerosols (for example spray cans), oil sprays or pump sprays are inadequate for the control of pests such as flies, fleas, mites, mosquitoes, grasshoppers or cockroaches. It is also very suitable for users. Aerosol preparations are preferably active compounds I and II, solvents such as lower alcohols (eg methanol, ethanol, propanol, butanol), ketones (eg acetone, methyl ethyl ketone), paraffin hydrocarbons (eg , Kerosene) (boiling range is approximately 50-250 ° C.), dimethylformamide, N-methylpyrrolidone, dimethyl sulfoxide, aromatic hydrocarbons such as toluene, xylene, water, further auxiliaries such as emulsifiers such as sorbitol Monooleates, oleyl ethoxylates with 3 to 7 mol of ethylene oxide, fatty alcohol ethoxylates, parfum oils such as ethereal oils, esters of intermediate fatty acids and lower alcohols, aromatic carbonyl compounds, where appropriate Stabilizers such as sodium benzoate, amphoteric surfactants, lower epoxides, triethyl orthoformate, and if necessary propellants such as propane, butane, Cattle, is composed of a mixture of compressed air, dimethyl ether, carbon dioxide, nitrous oxide, or these gases.

Oil spray formulations differ from aerosol formulations in that no propulsion system is used.

The combinations of the compounds according to the invention, and their respective compositions comprising a carrier, can also be used in mosquito coils and fumigation coils, smoke cartridges, evaporator plates, long term evaporators or other heat-independent evaporator systems.

Methods of controlling infectious diseases transmitted by insects (eg malaria, dengue and yellow fever, lymphadenitis and rischmanemia) with the mixtures of the present invention and their respective compositions also include surface treatment of temporary houses and houses, Impregnation of curtains, tents, apparel articles, bed nets, tsetse traps and the like and air spraying. Insecticide compositions for application to fibers, fabrics, knits, nonwovens, reticular materials or foils and tarpaulins preferably comprise a mixture comprising an insecticide, optionally a repellent and at least one binder.

The compositions according to the invention can be prepared from ants and / or termites from wood, such as wood, fences, sleepers, etc., and buildings, such as houses, detachments, factories, as well as building materials, furniture, leather, textiles, vinyl articles, wires and It can be used to protect cables and the like, and also to control ants and termites from harming crops or humans (eg, when pests invade houses and public places). The composition according to the invention is applied to the surrounding soil surface or to the lower layer soils to protect the wood material, as well as logging products such as lower layer concrete, sperm columns, beams, plywood, furniture and the like, wooden articles such as particle boards, half boards and the like. And surfaces of vinyl articles such as coated wires, vinyl sheets, insulation, such as styrene foam, and the like. When applied to ants that are harmful to crops or humans, the ant control compositions of the present invention are applied either directly or through bait contact to the anthill or its surroundings.

Mixtures of compounds I and II or compositions according to the invention can also be applied prophylactically in places where the appearance of pests is expected.

In the case of soil treatment or in the application to pest dwellings or nests, the amount of the composition with the active compound ranges from 0.0001 to 500 g per 100 m ² , preferably from 0.001 to 20 g per 100 m ² .

Typical application rates for the protection of materials are, for example, from 0.01 g to 1000 g of the active compound per m ² treated material, preferably from 0.1 g to 50 g per m ² .

Insecticide compositions for use in the impregnation of materials typically contain from 0.001 to 95% by weight, preferably from 0.1 to 45% by weight, more preferably from 1 to 25% by weight of the composition with the active compound.

When used in bait compositions, typical contents of compositions with active compounds I and II are 0.0001% to 15% by weight, preferably 0.001% to 5% by weight of active compound. The composition used may also comprise other additives such as solvents, flavors, preservatives, dyes or bitters of the active substance. In addition, its attractiveness can be enhanced by a particular color, shape or texture.

When used in spray compositions, the content of the composition with active compounds I and II is from 0.001 to 80% by weight, preferably from 0.01 to 50% by weight and most preferably from 0.01 to 15% by weight.

When used in the treatment of agricultural plants, the application rate of the composition with active compounds I and II according to the invention is from 0.1 g to 4000 g per hectare, preferably from 25 g to 600 g per hectare, more preferably 50 g per hectare. To 500 g.

It is also an object of the present invention to provide a composition suitable for treating, controlling, preventing and protecting warm blooded animals, including humans, and fish against invasion and infection by pests. Problems that may be encountered in pest control on or in animals and / or humans are those described in the introduction, i.e. reduction in application rates and / or combination of enhanced spectrum of activity spectrum and / or knock-down activity with extended control and / or Or similar to the need for tolerance management.

The present invention also includes the administration or application of an insecticidal effective amount of a mixture according to the invention orally, topically or parenterally to warm blooded animals, including humans, and fish. Provided are methods for treating, controlling, preventing and protecting said animals against invasion or infection by pests of Terra, Ortopera, Acarina, Pitilapera and Diphthera.

The present invention also provides for the infestation or infection by pests of siponaftera, himenopterra, hemitera, ortoptera, acarina, ptyrabtera and diphthera, comprising pesticidal effective amounts of the mixtures according to the invention. A method of preparing a composition for treating, controlling, preventing or protecting a warm blooded animal or fish is provided.

The method is particularly useful for controlling and preventing invasion and infection in warm-blooded animals such as cattle, sheep, pigs, camels, deer, horses, poultry, goats, dogs and cats, as well as humans.

This includes, but is not limited to, invasion of warm-blooded animals and fish from vampires, mites, onion roots, cacti, vampire flies, muscoid flies, flies, miacic fly larvae, hair mites, horns, mosquitoes and fleas. It can be controlled, prevented or eliminated by the mixtures according to the invention.

For oral administration to warm blooded animals, the compositions according to the invention can be formulated as animal feed, animal feed premix, animal feed concentrates, pills, solutions, pastes, suspensions, trenches, gels, tablets, boluses and capsules. have. In addition, the mixtures according to the invention can be administered to the animals in drinking water. For oral administration, the chosen dosage form should provide the animal with a mixture of 0.01 mg / kg animal weight to 100 mg / kg animal weight per day.

Alternatively, the composition according to the invention may be administered to the animal parenterally, for example by intravenous, intramuscular, intravenous or subcutaneous injection. The mixtures according to the invention can be dispersed or dissolved in physiologically acceptable carriers for subcutaneous injection. Alternatively, the composition according to the invention may be formulated as an implant for subcutaneous administration. In addition, the compositions according to the invention can be administered to animals transdermally. For parenteral administration, the chosen dosage form should provide a composition of 0.01 mg / kg body weight to 100 mg / kg body weight per day.

The compositions according to the invention can also be applied topically to animals in the form of dips, dusts, powders, collars, medals, sprays, spot-on and pore-on preparations. For topical application, dips and sprays typically contain 0.5 ppm to 5,000 ppm, preferably 1 ppm to 3,000 ppm of the compound of the present invention. The compositions according to the invention can also be formulated as ear tags for animals, in particular quadrupeds such as cattle and sheep.

Thus, in a further aspect of the invention there is provided the use of a composition according to the invention in the manufacture of a veterinary medicine, in particular an antiparasitic medicine.

The following experiments are intended to explain the synergistic effect of the compositions according to the invention. The following tests demonstrate the efficacy of controlling against certain pests of the compositions of the present invention. However, the pest control protection provided by the compositions of the present invention is not limited to these species. In certain cases, it has been found that the compositions of the present invention have a synergistic effect against certain other important invertebrate pests.

Use Example

The purpose of the following examples is to illustrate the compositions according to the invention and their insecticidal activity, but is not intended to limit the invention to these examples.

Synergy can be described as an interaction where the combined effect of two or more compounds is greater than the sum of the individual effects of each compound. The presence of a synergistic effect between the two mixing partners, expressed in percent control rates, can be attributed to the Lymphel equation (Richer, 1987; Colby, 1967; Limpel et al., 1962, Calculating Synergistic), often referred to as the Colby equation. and Antagonistic Responses in Herbicide Combinations, Weeds, 15, 20-22].

E = X + Y-XY / 100

E = Expected Percent Mortality of Combination of Compounds I and II

X = percent mortality of compound X measured independently

Y = percent mortality of compound Y measured independently.

Synergy is demonstrated when the percentage mortality observed for the combination is greater than the expected percentage mortality calculated by the Rimpel equation. That is, when the observed combined control effect is greater than the expected combined control effect (E), the combined effect is synergistic.

Analysis of synergy or antagonism between the compositions according to the invention was determined using the Rimpel equation.

Farmland experiments and foliar application were performed using commercially active compounds. The composition according to the invention was used as tank-mix at a predetermined concentration and applied to arable land at a final application rate of 400 liters per hectare. The observed results are summarized as follows:

1. Activity against mite pest Brevipalpus poenisis on coffee plants

Experiments were performed on coffee plants and the percent mortality observed 10 days after application is indicated by the observed efficacy. The results are summarized below:

2. Activity against Mite Pest Anticarcia Gemmatalis on Soybean Plants

Experiments were carried out on soybean plants and the percent mortality observed 7 days after application is indicated by the observed efficacy. The results are summarized below:

3. Activity against Leaf Beetle Pseudoflusia influenzae in Soybean Plants

Experiments were carried out on soybean plants and the percent mortality observed 7 days after application is indicated by the observed efficacy. The results are summarized below:

Claims (12)

As the active ingredient,
1) Benzoylurea compound of formula (I) or an agriculturally acceptable salt thereof; And
(I)

(Wherein,
R is halogen, C ₁ -C ₄ alkyl, C ₁ -C ₄ alkoxy or C ₁ -C ₄ alkylthio;
R ¹ is hydrogen, halogen, C ₁ -C ₄ alkyl, C ₁ -C ₄ alkoxy or C ₁ -C ₄ alkylthio;
R ² is fluorine;
R ³ is hydrogen, halogen, nitro, cyano, C ₁ -C ₄ alkyl or C ₁ -C ₄ haloalkyl;
n is an integer of 0, 1, 2 or 3;
R ⁴ is halogen or OR ⁵ ;
R ⁵ is substituted with up to 3 groups independently selected from C ₁ -C ₄ haloalkyl, C ₃ -C ₇ halocycloalkyl, phenyl which is halogen, C ₁ -C ₄ haloalkyl group, cyano group or nitro group Or may be unsubstituted), 2-pyridyl (may or may not be substituted with up to 3 groups independently selected from halogen atoms, C ₁ -C ₄ haloalkyl groups, cyano groups or nitro groups) being)
2) a compound of formula (II) or an agriculturally acceptable salt thereof
<Formula II>

A pesticidal composition comprising a synergistically effective amount. A compound of formula I according to claim 1, wherein the compound of formula I is N-[[[4- [2-chloro-4- (trifluoromethyl) phenoxy] -2-fluorophenyl] amino] carbonyl] -2,6 Insecticidal composition which is difluorobenzamide. A pesticidal composition according to claim 1 or 2 comprising the compound of formula I and the compound of formula II in a weight ratio of 100: 1 to 1: 100. A process for the preparation of a pesticidal composition according to any one of claims 1 to 3 comprising mixing a compound of formula (I) with a compound of formula (II). Use of a pesticidal composition as defined in any of claims 1 to 4 for combating invertebrate pests. Invertebrate pests, their food sources, their habitat or their breeding grounds, or the plants, seeds, soil, zones, materials or environment in which the pests are growing or may grow, or materials, plants, seeds which are intended to be protected from pest attack or invasion A method of controlling invertebrate pests, comprising treating a soil, surface or space with a synergistically effective amount of a composition as defined in any one of claims 1 to 3. Treating and / or protecting the plant from attack or infestation of a pest, comprising contacting the plant, or the soil or water in which the plant is growing, with a composition as defined in any one of claims 1 to 3. Way. 8. The method of claim 7, wherein the plant is a crop plant selected from lost plants, potatoes, rice, cereals, soybeans, drybeans, cotton, vegetables, coffee, sugar cane and horticultural plants. The method according to claim 6, wherein the composition comprising the compounds of formulas (I) and (II) is applied in foliar application. A method of protecting a plant propagation material and / or a plant growing therefrom, comprising treating the plant propagation material with a composition as defined in claim 1. The method according to any one of claims 6 to 10, wherein the composition as defined in any one of claims 1 to 3 is applied in an amount of 5 to 500 g per hectare for each individual compound. . The method according to any one of claims 6 to 11, wherein the compounds I and II as defined in any one of claims 1 to 3 are applied simultaneously, ie jointly or separately, or continuously. .