KR20110128878A - 큐프레독신 유래 펩티드의 변형 및 이의 사용방법 - Google Patents

큐프레독신 유래 펩티드의 변형 및 이의 사용방법 Download PDF

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KR20110128878A
KR20110128878A KR1020117021741A KR20117021741A KR20110128878A KR 20110128878 A KR20110128878 A KR 20110128878A KR 1020117021741 A KR1020117021741 A KR 1020117021741A KR 20117021741 A KR20117021741 A KR 20117021741A KR 20110128878 A KR20110128878 A KR 20110128878A
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cupredoxin
amino acid
peptide
isolated peptide
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타파스 다스 굽타
크레익 비티
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씨디쥐 테라퓨틱스, 인크.
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Abstract

본 발명은 개선된 약물 동력학 성질을 갖는 약학적 활성을 갖는 변형된 큐프레독신 유래 펩타이드를 제공하고, 이를 이용하여 약학적 활성과 관련된 다양한 질환을 앓는 포유류를 치료하는 방법을 제공한다. 큐프레독신 유래 펩타이드의 변형은 펩타이드의 혈장 반감기를 증가시키며, 약학적 활성의 특이적인 활성을 증가시키고, 면역원성을 감소시키고, 펩타이드의 생체 내 변화를 감소시키는 아미노산 서열 변이체 및 구조적 유도체를 포함한다. 변형된 큐프레독신 유래 펩타이드는 암, 부적절한 혈관 생성과 관련된 질환, 바이러스 및 세균 감염, 구체적으로 HVV 및 말라리아, 에프린 신호전달과 관련된 질환을 앓는 포유류를 치료하는 방법에 사용될 수 있고, 진단 화합물을 포함하는 카르고 화합물을 암세포에 전달하는 방법에 사용될 수 있다.

Description

큐프레독신 유래 펩티드의 변형 및 이의 사용방법{MODIFICATIONS OF CUPREDOXIN DERIVED PEPTIDES AND METHODS OF USE THEREOF}
본원은 35 U.S.C §§ 119 및 120에 의거한 우선권을 주장하며, 우선권 주장의 대상이 되는 출원은, 2007년 12월 14일 출원된 미국특허 출원 번호 61/013,709에 대하여 우선권을 주장하는 2008년 12월 15일에 출원된 미국특허 출원 번호 12/314,703의 일부로서 출원계속 중인 2009년 2월 19일에 출원된 미국특허 출원 번호 12/389,120의 일부로서 출원계속 중이며; 2006년 9월 11일에 출원된 미국 가출원 번호 11/853,497에 대하여 우선권을 주장하는 2007년 9월 11일에 출원된 미국특허 출원 번호 11/853,497의 일부로서 출원계속 중이며; 2004년 10월 7일에 출원된 미국 가출원 번호 60/616,782, 2005년 5월 13일에 출원된 미국 가출원 번호 60/680,500 및 2005년 7월 19일에 출원된 미국 가출원 번호 60/700,297에 대하여 우선권을 주장하는 2005년 10월 6일에 출원된 미국특허 출원 번호 11/244,105의 일부로서 출원 계속 중이다. 상기 이러한 출원의 모든 내용은 본 명세서에 참고로 포함된다.
본 발명은 개선된 약물 동력학 성질을 가지는 약리학적 활성을 갖는 변형된 큐프레독신 유래 펩타이드에 관한 것이고, 약리학적 활성과 관련된 다양한 질환을 앓는 포유류를 치료하기 위해 이를 사용하는 방법에 관한 것이다. 큐프레독신 유래 펩타이드의 변형은 펩타이드의 혈장 반감기를 증가시키며, 약학적 활성의 구체적인 활성을 증가시키고, 면역원성을 감소시키며, 및/또는 펩타이드의 생체 내 변화를 감소시킬 수 있는 아미노산 서열 변이체 및 구조적 유도체를 포함한다. 변형된 큐프레독신 유래 펩타이드는 암, 부적절한 혈관생성, 바이러스 및 세균 감염과 관련된 질환, 구체적으로 HIV와 말라리아, 에프린 신호전달과 관련된 질환을 치료하는 방법에 사용될 수 있고, 진단 화합물을 포함하는 카르고 화합물을 암세포에 전달하는 데에 사용될 수 있다.
녹농균으로부터 유래된 큐프레독신 아주린은 유망한 신규한 치료 및 진단 분자이다. 녹농균에 의해 만들어진 두 개의 산화-환원성(redox) 분자인 큐프레독신 아주린 및 시토크롬 c551(Cyt c551) 둘 모두는 J774 세포에 진입하고, 정상 세포에 비해 인간 암 세포에서 현저한 세포독성 활성을 보여준다(Zaborina 등, Microbiology 146: 2521-2530 (2000)). 또한, 아주린은 인간 흑색종 UISO-Mel-2 또는 인간 유방암 MCF-7 세포에 진입할 수 있다(Yamada 등, PNAS 99:14098-14103 (2002); Punj 등, Oncogene 23:2367-2378 (2004); Yamada 등, Cell. Biol. 7:1418-1431 (2005)). 게다가, 녹농균으로부터 유래되는 아주린은 J774 쥣과의 망상세포성육종 세포에 우선적으로 진입하며, 함께 복합체를 형성하여 종양 억제 단백질 p53을 안정화시키고, p53의 세포 내 농도를 높이고, 세포사멸을 유도한다(Yamada 등, Infection and Immunity, 70:7054-7062 (2002)). 또한, 아주린은 비-암성 세포에 비해 인간 골육종에서 현저히 증가된 세포사멸을 초래했다(Ye 등, Ai Zheng 24:298- 304 (2003)). 또한, 티오바실러스 페로옥시단스(Thiobacillus ferrooxidans)로부터 유래된 박테리아루스티시아닌은 대식세포에 진입하여 세포사멸을 유도할 수 있다(Yamada 등, Cell Cycle 3:1182-1187 (2004); Yamada 등, Cell. Micro. 7:1418-1431 (2005)). 포르미디움 라미노섬(Phormidium laminosum)로부터 유래된 플라스토시아닌 및 아크로모박터 시클로클라스테스(Achromobacter cycloclastes)로부터 유래된 슈도아주린은 대식세포에 대하여 세포독성이다(2006년 2월 23일에 공개된, 미국특허 공개공보 제20060040269호). 아주린 분자의 다양한 도메인의 구체적인 연구는 아미노산 50번 내지 77번(p28)(서열번호:13)이 국재화(internalization)와 이후의 세포사멸 활성에 치명적인 추정상의 단백질 전달 도메인(PTD)을 보여준다고 시사했다. 비록 세포 진입의 가능한 경로가 발견되지 않았지만(Yamada 등, Cell. Microbial. 7:1418-1431 (2005)), 아주린은 다른 약학적 활성의 치료적 중요성을 갖는다고 현재 알려져 있다. 아주린은 인간 배꼽 혈관 내피 세포(HUVECs)의 혈관생성을 억제하는 것으로 알려져 있다(2006년 7월 19일에 출원된 미국특허 출원번호 11/488,693). 또한, 녹농균으로부터 유래된 아주린은 말초 혈액 단핵 세포에서 HIV-1 감염의 성장을 억제하는 능력 및 말라리아에 감염된 포유류의 적혈구의 기생출혈증을 억제하는 능력을 갖는 것으로 알려져 있다(Chaudhari 등, Cell Cycle. 5: 1642-1648 (2006)). 또한, 녹농균으로부터 유래된 아주린은 다양한 포유류 세포 및 조직에서 에프린 신호전달 시스템을 교란하는 것으로 알려져 있다(2006년 5월 19일에 출원된 미국특허 출원번호 11/436,592).
그러므로, 아주린, 구체적으로 아주린으로부터 유래된 두 개의 펩타이드인 18-mer 및 28-mer는 치료적으로 그리고 진단상에 유용하다고 알게 되었다. 반면에, 환자의 신체에서 치료제의 효능은 몇몇의 인자에 의존한다. 치료 약물 자체의 활성 이외에, 치료 약물의 약물 동력학 성질 및 약물이 투여된 이후에 어떻게 그 장소에서 다양한 과정과 관련되는지, 즉 흡수, 분배, 물질대사 및 배출이 있다. 약물의 이러한 약물 동력학 성질은 어떻게 그리고 어느 정도의 이러한 생물학적 과정이 투여된 약물의 효능에 영향을 주는지를 설명하고, 이러한 성질은 혈류 중의 약물 반감기, 간에서 약물의 최초 물질대사, 약물의 용적분포, 약물에 결합하는 알부민의 정도 등을 포함한다. 이러한 약물 동력학 성질 각각은 약물의 효능 상에 지대한 영향을 미칠 수 있다.
환자의 혈류 안으로 약물의 흡수 부위는 투여 경로에 의존한다. 예를 들어, 경구적으로 투여된 약물은 상기 약물의 화학적 그리고 물리적 성질 때문에 다른 부위보다 소화관의 한 부위에서 더 잘 흡수될 수 있다. 다른 한편으로. 비경구적 투여에 의한 흡수는 경구 투여보다 빠를 뿐만 아니라, 약물의 혈중 수준은 훨씬 더 예측 가능하다. 왜냐하면 훨씬 더 적은 약물이 소실되기 때문이며, 특히 정맥 내 투여의 경우 그러하다. 생물학적 이용 가능성은 체순환에 도달하는 투여된 약물의 분율이다.
혈류로부터 세포외액(간질조직) 및/또는 조직의 세포로 약물의 분배는 약물의 다양한 양태에 의해 변화될 수 있다. 신체에서 약물의 분배는 "약물의 용적분배"로 표현될 수 있으며, 이는 약물이 퍼뜨려지는 액체의 가상적인 용적이다. 약물의 구조는 소수성 약물이 대부분의 생체막을 더 손쉽게 가로질러서 조직의 세포 내에 분배될 수 있는 약물 분배에 영향을 미칠 수 있다. 또한, 약물은 혈액 단백질 및 주변 조직 안으로의 통로에 결합될 수 있으며, 이에 의하여 지연되었다. 예를 들어, 혈류에서, 나프록센은 혈장 단백질에 99 % 결합되며, 페니실린 G는 60 % 결합되며, 아목시실린은 단지 20 % 결합되고 미녹시딜(minoxidil)은 결합되지 않는다. Howard C. Ansel 등, Pharmaceutical Dosage Forms and Delivery Systems 129(Lippincott, Williams and Wilkins 1999). 결합된 약물은 신체의 약물 중독치료 과정에 노출되지 않거나, 사구체를 통해 여과함으로써 혈류로부터 제거되지 않는다. 결합된 약물은 결합되지 않은 부분이 활성 부분으로 고려되는 것과 다르게 비활성 부분을 나타낸다. 약물의 결합된 부분은 자유 약물이 더 이상 단백질 포화를 보장하기에 충분하지않는 경우에 결합되지 않은 활성 형태로 혈류 안으로 방출되는 약물의 저장소의 역할을 한다. 그러므로, 혈류에서 결합된 약물은 더 긴 시간 동안 신체에 남아 있을 것이고, 덜 빈번한 투여량이 요구될 것이다.
또한, 환자에게서 약물의 물질대사는 이의 효능에 영향을 미칠 것이다. 수많은 약물은 신체로부터 배출되기 이전에 생체 내 변화를 겪는다. 약물의 생체 내 변화는 보다 수용성이고, 광석 이온화되고, 혈장 및 조직 중의 단백질에 결합을 잘 못하고, 세포막에 침투를 잘 못하고, 약물이 더 적은 약학적으로 활성을 만드는 다른 양태인 약물의 형태를 야기할 수 있다. 그러므로, 생체 내 변화된 약물은 더 적은 독성을 제공할 수 있고, 더 손쉽게 배출될 수 있다. 약물이 생체 내 변화되는 4가지 주요한 방식이 있다: 산화, 환원, 가수분해 및 콘쥬게이션. 산화 반응은 간 세포 내에 소포체에 결합된 산화효소에 의해 최초 촉진된다. 환원 반응은 내장 및 간에서 최초 환원효소에 의해 촉진된다.
가수분해는 간에서 최초로 에스테라아제(esterases)에 의해 촉진된다. 약물의 가장 흔한 생체 내 변화 경로인 글루쿠로니드 콘쥬게이션은 약물과 글루쿠론산과의 조합에 의해 발생하며, 신체로부터 쉽게 제거되는 약물의 이온형태를 형성한다(Christensen 등, J. Pharm. Pharmacol. 37:91-95 (1985)). 제거를 증가시키는 다른 생체 내 변화는 메틸화 및 아실화를 포함한다.
신체로부터 약물의 배출은 다양한 경로에 의해 발생될 수 있다. 신장은 요소 중의 약물을 제거하는 지배적인 역할을 담당한다. 반면에, 약물은 간을 통해 혈장으로부터 제거될 수도 있다. 특히, 경구적으로 투여되는 약물의 경우, 간은 약물의 혈장 반감기를 결정하는데에 중요한 역할을 담당할 수 있다.
본 발명의 목적은 큐프레독신 유래 펩티드를 변형하고 이를 사용하는 방법을 제공하는 것이다.
본 발명의 일 양태는 큐프레독신 유래 펩타이드의 변이체, 절단 또는 유도체인 단리된 변형 큐프레독신 유래 펩타이드를 제공한다. 일부 실시예에서, 상기 변형은 고리화 반응을 포함한다. 고리화 반응의 일 실시예는 효소성 고리화 반응이 있다. 또 다른 실시예에서, 상기 고리화 반응은 티오에테르 고리를 만든다. 또 다른 실시예에서, 상기 티오에테르 고리는 시스테인 잔기를 디히드로알라닌 및 디히드로부트린 잔기에 첨가함으로써 형성된다. 또 다른 실시예에서, 상기 디히드로알라닌 및 디히드로부트린 잔기는 세린 및 트레오닌 각각의 탈수로부터 유래된다. 또 다른 실시예에서, NisB는 상기 세린 및 트레오닌을 탈수시킨다.
일 실시예에서, 상기 단리된 변형 큐프레독신 유래 펩타이드는 비-변형 큐프레독신 유래 펩타이드에 비해 약물 동력학 성질이 개선되었다. 상기 개선된 약물 동력학 성질은 (1) 환자의 생체 내 변화에 덜 영향 받는 성질, (2) 환자의 신체로부터 느린 속도로 외부로 방출되는 성질, (3) 이의 3차 구조의 안정성을 증가시키는 성질, 그리고 (4) 연장된 혈장 반감기를 갖는 하나 이상의 펩타이드일 수 있다. 게다가, 상기 단리된 펩타이드는 큐프레독신의 적어도 하나의 약물학적 활성을 가질 수 있다. 관심이 있는 구체적인 약물학적 활성은 (1) 포유류의 암세포에 진입하는 활성, (2) 비-암성 포유류 세포에는 진입하지 않는 활성, (3) 전암성 포유류 세포에 진입하는 활성, (4) 포유류의 암세포를 죽이는 활성, (5) 전암성 포유류 세포를 죽이는 활성, (6) 포유류의 암세포의 성장을 억제하는 활성, (7) HIV-1 감염을 억제하는 활성, (8) 말라리아에 감염된 적혈구의 기생충혈증을 억제하는 활성, (9) 에프린 신호전달계를 교란하는 활성, (10) 혈관생성을 억제하는 활성을 포함한다.
상기 변형된 큐프레독신 유래 펩타이드는 녹농균(Pseudomonas aeruginosa), 포르미디움 라미노섬(Phormidium laminosum ), 울바 페르투시스(Ulva pertussis), 티오바실러스 페로옥시단스(Thiobacillus ferrooxidans), 아크로모박터 시클로클라스테스(Achromobacter cycloclastes), 슈도모나스 시린게(Pseudomonas syringae), 수막구균(Neisseria meningitidis), 장염비브리오균(Vibrio parahaemolyticus), 보데텔라 브론키셉티카(Bordetella bronchiseptica), 보르데텔라 백일해균(Bordetella pertussis), 클로로플렉서스 오란티아쿠스(Chloroflexus aurantiacus) 및 임균(Neisseria gonorrhoeae)으로부터의 큐프레독신으로부터 유래될 수 있다. 상기 큐프레독신은 아주린, 플라스토시아닌, 루스티시아닌, 슈도아주린, 오라시아닌(auracyanin), 스텔라시아닌, 오이 기본 단백질 및 아주린-유사 단백질일 수 있다. 구체적인 실시예에서, 상기 큐프레독신은 서열번호:1 내지 서열번호:12 중 어느 하나일 수 있다. 상기 단리된 변형 큐프레독신 유래 펩타이드는 상기 큐프레독신의 절단일 수 있다. 구체적인 실시예에서, 상기 펩타이드는 서열번호:13 내지 서열번호:47 중 하나일 수 있다. 다른 구체적인 실시예에서, 서열번호:1 내지 서열번호:12는 상기 단리된 펩타이드에 적어도 90 % 일치한다. 일부 실시예에서, 상기 단리된 변형 큐프레독신 유래 펩타이드는 상응하는 비-변형된 큐프레독신보다 가수 분해에 대하여 덜 영향받을 수 있다. 특히, 상기 단리된 펩타이드는 다른 아미노산 잔기, 구체적으로 글루탐산 또는 트레오닌 잔기로 치환되는 큐프레독신 유래 펩타이드의 서열에 하나 이상의 아스파라긴 또는 세린 잔기를 가질 수 있다.
일부 실시예에서, 상기 단리된 변형 큐프레독신 유래 펩타이드는 탈아미노화 반응에 덜 영향 받는다. 구체적인 실시예에서, 상기 큐프레독신 유래 펩타이드 중 하나 이상의 글리신 잔기는 다른 아미노산 잔기, 구체적으로 트레오닌 또는 알라닌 잔기로 치환된다. 일부 실시예에서, 녹농균 아주린(서열번호:1)의 58번 또는 63번 잔기와 동일한 상기 큐프레독신 유래 펩타이드 중의 하나 이상의 글리신 잔기는 치환될 수 있다. 또 다른 구체적인 실시예에서, 상기 단리된 펩타이드는 서열번호:30을 포함할 수 있다.
일부 실시예에서, 상기 단리된 변형 큐프레독신 유래 펩타이드는 산화 반응에 덜 영향받는다. 특히, 상기 단리된 펩타이드는 다른 아미노산 잔기, 구체적으로 루신 또는 발린 잔기로 치환되는 큐프레독신 유래 펩타이드의 하나 이상의 메티오닌 또는 시스테인 잔기를 가질 수 있다. 구체적인 실시예에서, 녹농균 아주린(서열번호:1)의 56번 또는 64번 잔기와 동일한 상기 큐프레독신 유래 펩타이드 중 하나 이상의 메티오닌 잔기는 치환된다. 또 다른 구체적인 실시예에서, 상기 단리된 펩타이드는 서열번호:31 또는 서열번호:32를 포함할 수 있다. 일부 실시예에서, 상기 단리된 변형 큐프레독신 유래 펩타이드는 디케토피페라진 및 피로글루탐산 형성에 덜 영향받을 수 있다. 특히, 상기 단리된 펩타이드는 다른 아미노산 잔기로 치환되는 상기 큐프레독신 유래 펩타이드의 N-말단으로부터 1, 2 또는 3번 위치에 글리신 잔기를 가질 수 있다. 나아가, 상기 단리된 펩타이드는 다른 아미노산 잔기로 치환되는 큐프레독신 유래 펩타이드의 N-말단으로부터 3번째 위치에 프롤린 잔기를 가질 수 있다. 나아가, 상기 단리된 펩타이드는 다른 아미노산 잔기로 치환되는 큐프레독신 유래 펩타이드의 N-말단에 아스파라긴 잔기를 가질 수 있다.
일부 실시예에서, 상기 단리된 변형 큐프레독신 유래 펩타이드는 라세미화에 덜 영향받을 수 있다. 특히, 상기 단리된 펩타이드는 아미노산 잔기의 D-이성질체로 치환된 큐프레독신의 하나 이상의 아미노산 잔기를 가질 수 있다. 구체적인 일 실시예에서, 상기 큐프레독신 유래 펩타이드의 모든 아미노산 잔기는 아미노산 잔기의 D-이성질체로 치환된다. 또 다른 구체적인 실시예에서, 상기 단리된 펩타이드는 서열번호:45를 포함한다.
일부 실시예에서, 상기 단리된 변형 큐프레독신 유래 펩타이드는 분해(degradation)에 덜 영향받을 수 있다. 특히, 상기 큐프레독신 유래 펩타이드의 N-말단은 아세틸화 될 수 있다. 나아가, 상기 큐프레독신 유래 펩타이드의 C-말단은 아미드화될 수 있다. 구체적인 일 실시예에서, 상기 단리된 펩타이드는 서열번호:33이다. 일부 실시예에서, 상기 단리된 변형 큐프레독신 유래 펩타이드는 이의 3차원 구조의 안정성을 증가시키도록 변형된다. 특히, 상기 단리된 펩타이드는 적어도 하나의 α-나선의 안정성을 증가시키도록 변형될 수 있다. 일 실시예에서, 큐프레독신 유래 펩타이드 중 적어도 하나의 글리신, 프롤린, 세린, 아스파르트산, 알라닌, 트레오닌, 발린, 글루타민, 아스파라긴, 시스테인, 히스티딘, 리신 및 아르기닌 아미노산 잔기는 루신, 이소루신, 페닐알라닌, 글루탐산, 티로신, 트립토판 또는 메티오닌으로 치환된다. 구체적인 실시예에서, 상기 큐프레독신 유래 펩타이드 중 치환된 잔기는 녹농균 아주린의 53번 내지 56번, 58번 내지 64번 및 68번 내지 70번 잔기에 상응하는 잔기 내에 있을 수 있다. 다른 구체적인 실시예에서, 녹농균 아주린의 57번 잔기에 상응하는 잔기에서 상기 글루타민은 트립토판 잔기로 치환될 수 있으며, 녹농균 아주린의 52번 잔기에 상응하는 잔기에서 트레오닌은 트립토판 잔기로 치환될 수 있으며, 녹농균 아주린의 61번 잔기에 상응하는 잔기에서 트레오닌은 트립토판 잔기로 치환될 수 있으며, 및/또는 녹농균 아주린의 63번 잔기에 상응하는 잔기에서 글리신은 트립토판 잔기로 치환된다. 다른 구체적인 실시예에서, 상기 단리된 펩타이드는 서열번호:34 내지 서열번호:44 중 하나를 포함한다.
다른 실시예에서, 단리된 펩타이드는 ε-(3,5-디니트로벤조일)-리신 잔기가 i(i+4) 간격으로 치환된 큐프레독신 유래 펩타이드 중 두 개 이상의 리신 잔기를 가질 수 있다. 특히, 상기 큐프레독신 유래 펩타이드의 치환된 잔기는 녹농균 아주린의 53번 내지 56번, 58번 내지 64번 및 68번 내지 70번 잔기에 상응하는 잔기 내에 있을 수 있다.
다른 실시예에서, 단리된 펩타이드는 i(i+4) 간격으로 큐프레독신 유래 펩타이드에 치환된 히스티딘-시스테인 또는 히스티딘-히스티딘 잔기쌍을 가질 수 있고, 적어도 Cu, Zn, Cd 및 Ru 중 하나를 가질 수 있다. 구체적인 실시예에서, 상기 단리된 펩타이드는 녹농균 아주린의 53번 내지 56번, 58번 내지 64번 및 68번 내지 70번 잔기에 상응하는 잔기 내에 상기 큐프레독신 유래 펩타이드의 치환된 잔기를 가질 수 있다.
또 다른 실시예에서, 상기 단리된 펩타이드는 자생 아미노산에 일치하는 올레핀 함유 테더(tether)를 포함하는 α,α-이치환된 비-천연 아미노산으로 치환된 큐프레독신 유래 펩타이드의 하나 이상의 자생 아미노산 잔기쌍을 가질 수 있다. 상기 단리된 펩타이드는 녹농균 아주린의 53번 내지 56번, 58번 내지 64번 및 68번 내지 70번 잔기에 상응하는 잔기 내에 큐프레독신 유래 펩타이드의 치환된 잔기를 가질 수 있다.
일부 실시예에서, 단리된 변형 큐프레독신 유래 펩타이드는 상기 큐프레독신 유래 펩타이드에 공유결합되는 하나 이상의 PEG(폴리에틸렌 글리콜) 분자를 가질 수 있다. 특히, 상기 단리된 펩타이드는 상기 큐프레독신 유래 펩타이드 중 하나 이상의 시스테인 잔기에 공유결합되는 하나 이상의 PEG 분자를 가질 수 있다. 구체적인 실시예에서, 상기 단리된 펩타이드는 녹농균 아주린(서열번호:1)의 3, 6 및 112번 잔기 중 하나 이상에 상응하는 하나 이상의 시스테인 잔기에 공유결합되는 하나 이상의 PEG 분자를 가질 수 있다. 다른 실시예에서, 시스테인 잔기는 큐프레독신 유래 펩타이드로 치환될 수 있고 PEG 분자에 공유결합될 수 있다.
또 다른 실시예에서, 상기 단리된 펩타이드는 큐프레독신 유래 펩타이드의 리신, 시스테인, 히스티딘, 아르기닌, 아스파르트산, 글루탐산, 세린, 트레오닌, 티로신, N-말단 아미노기, 또는 C-말단 카복실산에서 공유결합된 하나 이상의 PEG 분자를 가질 수 있다. 구체적인 실시예에서, 상기 단리된 펩타이드는 PEG 분자에 공유결합된 하나 이상의 리신 잔기 또는 C-말단 카복실산을 갖는다. 또 다른 실시예에서, 하나 이상의 리신, 시스테인, 히스티딘, 아르기닌, 아스파르트산, 글루탐산, 세린, 트레오닌 및 티로신 잔기는 큐프레독신 유래 펩타이드로 치환될 수 있고 PEG 분자에 공유결합될 수 있다.
다른 실시예에서, 하나 이상의 PEG 분자는 큐프레독신 유래 펩타이드 중 하나 이상의 아미노기에 공유결합될 수 있거나, 큐프레독신 유래 펩타이드에 무작위로 공유결합될 수 있다.
큐프레독신 유래 펩타이드 당 PEG 분자의 평균 분자량은 약 200 Da 내지 약 100,000 Da일 수 있다. 상기 큐프레독신 유래 펩타이드는 하나 이상의 분지된 PEG 분자에 공유결합될 수 있으며, 구체적으로 상기 분지된 PEG 분자는 약 50 kDa이다. 큐프레독신 유래 펩타이드는 하나 이상의 선형 PEG 분자에 공유결합될 수 있으며, 구체적으로 상기 선형 PEG 분자는 약 5 kDa이다. 본 발명의 또 다른 양태는 변형된 큐프레독신 유래 펩타이드 및 약학적으로 허용가능한 담체를 포함할 수 있는 약학 조성물이다.
본 발명의 또 다른 양태는 질환을 앓는 포유류에게 변형된 큐프레독신 유래 펩타이드의 치료적 유효량을 투여하는 단계를 포함할 수 있는, 질환을 앓고 있는 포유류를 치료하는 방법이다. 구체적 실시예에서, 상기 포유류는 인간이다.
본 발명의 또 다른 양태는 아미노산 서열 X1SX2AADX3X4X5VVX6DX7X8ASGLDKDYLKPDX9(서열번호:48)을 포함하거나, 그렇지 않으면 상기 서열로 구성되는 단리된 펩타이드이며; 상기 X1은 L 및 아세틸화된-L로 구성되는 군으로부터 선택되며; X2는 T 및 W로 구성되는 군으로부터 선택되며; X3는 M, L 및 V로 구성되는 군으로부터 선택되며; X4는 Q 및 W로 구성되는 군으로부터 선택되며; X5는 G 및 A로 구성되는 군으로부터 선택되며; X6은 T 및 W로 구성되는 군으로부터 선택되며; X7은 G, T 및 W로 구성되는 군으로부터 선택되며; X8은 M, L 및 V로 구성되는 군으로부터 선택되며; 그리고 X9는 D 및 아미드화된-D로 구성되는 군으로부터 선택된다.
본 발명의 또 다른 양태는 아미노산 서열 X1DPKLYDKDLGSAX2X3DX4VVX5X6X7DAAX8SX9(서열번호:49)을 포함하거나, 그렇지 않으면 상기 서열로 구성되는 단리된 펩타이드이며; 상기 X1은 D 및 아세틸화된-D로 구성되는 군으로부터 선택되며; X2는 M, L 및 V로 구성되는 군으로부터 선택되며; X3는 G, T 및 W로 구성되는 군으로부터 선택되며; X4는 T 및 W로 구성되는 군으로부터 선택되며; X5는 G 및 A로 구성되는 군으로부터 선택되며; X6은 Q 및 W로 구성되는 군으로부터 선택되며; X7은 M, L 및 V로 구성되는 군으로부터 선택되며; X8은 T 및 W로 구성되는 군으로부터 선택되며; 그리고 X9는 L 및 아미드화된-L로 구성되는 군으로부터 선택된다.
본 발명의 또 다른 양태는 서열번호:50 내지 서열번호:3504의 서열을 포함하거나, 그렇지 않으면 상기 서열로 구성되는 단리된 펩타이드이며, 상기 단리된 펩타이드는 본 명세서에 개시된 하나 이상의 기술 및 방법을 사용하여 변형된 큐프레독신 유래 펩타이드이다.
서열의 간단한 설명
서열번호:1은 녹농균으로부터 유래된 wt-아주린의 아미노산 서열이다.
서열번호:2는 포르미디움 라미노섬으로부터 유래된 플라스토시아닌의 아미노산 서열이다.
서열번호:3은 티오바실러스 페로옥시단스로부터 유래된 루스티시아닌의 아미노산 서열이다.
서열번호:4는 아크로모박터 시클로클라스테스로부터 유래된 슈도아주린의 아미노산 서열이다.
서열번호:5는 슈도모나스 시린게로부터 유래된 아주린의 아미노산 서열이다.
서열번호:6은 임균(Neisseria gonorrhoeae)으로부터 유래된 Laz의 아미노산 서열이다.
서열번호:7은 수막구균으로부터 유래된 Laz의 아미노산 서열이다.
서열번호:8은 장염비브리오균으로부터 유래된 아주린의 아미노산 서열이다.
서열번호:9는 보데텔라 브론키셉티카로부터 유래된 아주린의 아미노산 서열이다.
서열번호:10은 클로로플렉서스 오란티아쿠스로부터 유래된 오라시아닌 A의 아미노산 서열이다.
서열번호:11은 클로로플렉서스 오란티아쿠스로부터 유래된 오라시아닌 B의 아미노산 서열이다.
서열번호:12는 보르데텔라 백일해균으로부터 유래된 아주린의 아미노산 서열이다.
서열번호:13은 녹농균으로부터 유래된 wt-아주린(p28)의 50번 내지 77번 아미노산 절편의 아미노산 서열이다.
서열번호:14는 녹농균으로부터 유래된 wt-아주린(p28)의 50번 내지 67번 아미노산 절편의 아미노산 서열이다.
서열번호:15는 녹농균으로부터 유래된 wt-아주린의 36번 내지 128번 아미노산 절편의 아미노산 서열이다.
서열번호:16은 녹농균으로부터 유래된 wt-아주린의 36번 내지 89번 아미노산 절편의 아미노산 서열이다.
서열번호:17은 녹농균으로부터 유래된 wt-아주린의 36번 내지 77번 아미노산 절편의 아미노산 서열이다.
서열번호:18은 녹농균으로부터 유래된 wt-아주린의 36번 내지 50번 아미노산 절편의 아미노산 서열이다.
서열번호:19는 녹농균으로부터 유래된 wt-아주린의 50번 내지 66번 아미노산 절편의 아미노산 서열이다.
서열번호:20은 녹농균으로부터 유래된 wt-아주린의 67번 내지 77번 아미노산 절편의 아미노산 서열이다.
서열번호:21은 클로로플렉서스 오란티아쿠스의 오라시아닌 B 중 57번 내지 89번 아미노산 절편의 아미노산 서열이다.
서열번호:22는 보르텔라 백일해균으로부터 유래된 아주린의 50번 내지 77번 아미노산 절편의 아미노산 서열이다.
서열번호:23은 수막구균으로부터 유래된 Laz 단백질의 89번 내지 115번 아미노산 절편의 아미노산 서열이다.
서열번호:24는 녹농균으로부터 유래된 아주린의 53번 내지 70번 아미노산 절편의 아미노산 서열이다.
서열번호:25는 녹농균으로부터 유래된 아주린의 53번 내지 64번 아미노산 절편의 아미노산 서열이다.
서열번호:26은 녹농균으로부터 유래된 아주린으로부터의 51번 내지 77번 아미노산 절편 아미노산 서열이다.
서열번호:27은 슈도모나스 시린게로부터 유래된 아주린으로부터의 51번 내지 77번 아미노산 절편의 아미노산 서열이다.
서열번호:28은 장염비브리오균으로부터 유래된 아주린으로부터의 52번 내지 78번 아미노산 절편의 아미노산 서열이다.
서열번호:29는 보르텔라 브론키셉티가로부터 유래된 아주린으로부터의 51번 내지 77번 아미노산 절편의 아미노산 서열이다.
서열번호:30은 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:31은 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:32는 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:33은 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:34는 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:35는 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:36은 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:37은 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:38은 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:39는 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:40은 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:41은 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:42는 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:43은 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:44는 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:45는 녹농균 아주린의 50번 내지 77번 아미노산 영역이 변이된 형태의 인위적 서열이다.
서열번호:46은 D가 아스파르트산, G가 글리신, Y가 티로신, K가 리신 그리고 X가 임의의 아미노산인 아주린으로부터 보존된 아미노산 서열이다.
서열번호:47은 D가 아스파르트산, G가 글리신, Y가 티로신, K가 리신 그리고 X가 임의의 아미노산인 아주린으로부터 보존된 아미노산 서열이다.
서열번호:48은 농녹균의 아주린 50번 내지 77번에 대하여 변형을 갖는 인위적 서열이다.
서열번호:49는 농녹균의 아주린 50번 내지 77번의 D-이성질체에 대하여 변형을 갖는 인위적 서열이다.
서열번호:50 내지 서열번호:3504는 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3505는 Pep42의 아미노산 서열이며, 고리형 13-mer 올리고펩타이드이다.
서열번호:3506은 녹농균으로부터 유래된 wt-아주린의 66번 내지 77번 아미노산 절편(p12)의 아미노산 서열이다.
서열번호:3507은 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3508은 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3509는 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3510은 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3511은 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3512는 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3513은 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3514는 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3515는 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3516은 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3517은 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3518은 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3519는 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3520은 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3521은 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3522는 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3523은 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3524는 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3525는 녹농균 아주린의 50번 내지 77번 아미노산 영역의 변이체 형태에 대한 서열이다.
서열번호:3526은 녹농균 아주린으로부터 유래된 wt-아주린의 60번 내지 77번 아미노산 절편(p18b)의 아미노산 서열이다.
서열번호:3527은 Arg-8의 아미노산 서열이다.
도 1은 표지된 p18(서열번호:14)를 주입시킨 마우스의 전신 스캔 이미지를 묘사한다. IRDye®표지된 p18(서열번호:14)(125 μg)을 정맥내로 주입하였고, 흉선이 제거된 마우스를 표시된 시간에 암과 장기에 표지된 염료를 검출하기 위해 Odyssey® Infrared Imaging System을 사용하여 검사했다.
도 2는 표지된 p18(서열번호:14)를 주입시킨 마우스의 전신 스캔 이미지를 묘사한다. 주입 후 125 μg의 IRDye®표지된 p18(서열번호:14)을 정맥내로 120시간(죽이기 직전까지) 주입함. 절개한 장기를 검사했고, 이는 우측에 도시된다. p18(서열번호:14) 신호는 신장 및 Mel-2 종양으로부터 보여졌다.
도 3은 Mel-2 세포를 주입한 후 3 주째에 125 μg의 IRDye®표지된 p18(서열번호:14)를 Mel-2 피하 종양에 정맥내로 투여했으며, 48시간 후에 Odyssey® Infrared 검사를 수행했다. 800 nm 채널로 기록된 이미지는 IRDye®로부터의 특정 p18(서열번호:14)의 신호를 나타내고, 700 nm 채널로 기록된 이미지는 바탕을 나타낸다. p18(서열번호:14) 신호는 신장 및 Mel-2 종양으로부터 보여졌다.
도 4는 α-나선 구조를 갖는 아주린 절단 및 70 ns 시뮬레이션의 결과를 도시한다.
도 5는 시뮬레이션한 구조에서 Cα 원자간의 거리에 기초하여 p28(서열번호:13) 중 티오에테르 브릿지 위치를 측정한 것이다.
도 6 (a), (b) 및 (c)는 다양한 조직 발생 및 이들의 정상적인 반대쌍(counterpart)의 암세포주에 아주린 유래 펩타이드, p18(서열번호:14) 및 p28(서열번호:13)의 침투를 보여주는 사진을 묘사한다. (a) 37 ℃에서 2시간 후에 Alexafluor 568 표지된 p28(서열번호:13) 또는 p18(서열번호:14)의 침투를 보여주는 사진이다. 양이온 Arg-8(서열번호:3527)이 대조군으로 사용됐다. (b) 37 ℃에서 2시간 후에 동일한 세포주에 Alexafluor 568 표지된 p28(서열번호:13) 또는 p18(서열번호:14)의 침투에 대한 유세포 분석을 묘사하는 그래프이다. (c) 정상 세포로부터의 형광을 넘어서는 배수 증가를 묘사하는 그래프이다. 4개의 흑색종 세포주 안으로 들어가는 p28(서열번호:13) 또는 p18(서열번호:14)의 유사한 관찰은 정상 세포로부터의 형광을 넘어서는 수배의 증가를 보여준다.
도 7 (a) 및 (b)는 아주린 60번 내지 77번(p18b)(서열번호:3526) 및 아주린 66번 내지 77번(p12)(서열번호:3506)이 암세포 및 정상세포에 들어가는 것을 보여주는 사진을 묘사한다. 37 ℃에서 2시간 동안 (a) 세포를 Alexafluor 568 표지된 p18b(서열번호:3526)과 함께 또는 (b) p12(서열번호:3506)와 함께 배양했고, 공초점 현미경을 사용하여 이미지를 기록했다.
도 8은 아주린과 이의 펩타이드의 세포막 독성을 묘사하는 그래프이다. (a) 37 ℃에서 10분 동안 상이한 농도의 p28(서열번호:13), p18(서열번호:14) 및 아주린에 노출되는 UISOMel-2 세포의 LDH 누출 분석이다. 표준 세포 용해 완충제(독성-시약)를 양성 대조군으로서 포함했다. 노출 이후에 형광의 변화를 k,x 560 nm 및 kem 590 nm에서 측정했다. 세포 용해 완충제를 100 % LDH 방출로 정의했다. 데이터는 대조군의 양성 형광의 %를 나타낸다. 데이터는 평균±SEM으로서 보여진다. (b) p28(서열번호:13), p18(서열번호:14) 및 아주린과 함게 배양된 인간 적혈구로부터 헤모글로빈 누출. 인간 적혈구를 37 ℃에서 30분 동안 펩타이드와 함께 배양했고, 540 nm의 흡광도로 측정했다. 0.1 % Triton X-100 이후에 헤모글로빈 방출을 100 % 헤모글로빈 방출로 정의했다. 데이터는 세 번 반복된 측정의 평균±SEM을 나타낸다.
도 9 (a), (b), (c) 및 (d)는 온도 의존성 및 UISO Mel-2 세포 안으로 p28(서열번호:13) 및 p18(서열번호:14)의 경쟁적 내재화(internalization)를 보여주는 사진을 묘사한다. 다른 온도에서 2011M에서 공초점 현미경으로 (a) Alexafluor 568 표지된 p28(서열번호:13)의 침투 또는 (b) p18(서열번호:14)의 침투를 평가했다. (c) 및 (d) 미표지된 펩타이드의 존재/부존재 하에서 30분 동안 37 ℃에서 UISO-Mel-2 세포 안으로 p18을 5 μM로(200 배 초과) (c) Alexafluor 568 표지된 p28(서열번호:13)의 진입에 대한 공초점 분석 (d) 또는 p18(서열번호:14)의 진입에 대한 공초점 분석.
도 10 (a), (b), (c) 및 (d). (a) 헤파린 설페이트(100 μg/ml)의 존재/부존재하에 37 ℃에서 1시간 후에 UISO-Mel-2 세포에 진입한 p28, p18(서열번호:14)(20 μM) 및 Arg-8(서열번호:3527)(10 μM)의 공초점 분석을 보여주는 사진을 묘사한 것이다. (b) 억제제의 존재하에서 진입하는 p28(서열번호:13) 또는 p18(서열번호:14)의 유세포 분석을 보여주는 그래프이다. 억제제의 부존재 하에서(대조군) 세포 형광 강도를 100 %로 가정했다. (c) 억제제의 존재하에서 섬유아세포 안으로 진입하는 p28(서열번호:13) 및 p18(서열번호:14)의 FRCS 분석을 묘사하는 그래프이다. (d) 카베올린 I(패널 1)을 포함한 p18(서열번호:14) 및 p28(서열번호:13)을 동일위치에서 보여주는 사진을 묘사한 것이다. UISO-Mel-2 세포를 37 ℃에서 2시간 동안 Alexafluor 568 표지된 p18(서열번호:14) 또는 p28(서열번호:13)(20 μM)와 함께 배양하거나, 배지에서 배양했다. 세포를 고정했고, 항-카베올린 1 항체염색을 위해 처리했다. 37 ℃에서 2시간 후에 UISO-Mel-2 세포 안으로 Alexafluor 568 표지된 p18(서열번호:14) 또는 p28(서열번호:13)(20 μM)의 진입한 이후에 안티골긴(antigolgin) 97 항체(패널 2)의 공초점 분석이다. UISO-Mel-2 세포에서 미토트랙커(mitotracker)(녹색)(패널 3) 및 리소트랙커(Lysotracker)(녹색)(패널 4) 염료를 포함한 Alexafluor 568 표지된 아주린, p28(서열번호:13) 및 p18(서열번호:14)을 동일위치에서 보여준다. 세포를 20 μM 아주린, p28(서열번호:13), p18(서열번호:14)과 함께 또는 배지만으로 37 ℃에서 배양했다. 90분 배양 후, 미토트랙커/리소트랙커 프로브(probe)를 첨가했고 30분 동안 세포를 배양했다. 세포를 DAPI(청색)으로 대비염색(counterstain)했다. 동일한 위치의 아주린, p28(서열번호:13) 또는 p18(서열번호:14)는 황색 형광으로 나타난다.
도 11 (a) 및 (b). 37 ℃에서 72시간 동안 아주린, p28(서열번호:13) 또는 p18(서열번호:14)의 농도를 증가시키면서 배양한 UISO-Mel-2 세포를 묘사하는 그래프이다. (a) MTT; (b) 직접 세포 수. 대조군 웰에서 세포 생존 능력(MTT) 또는 세포 수를 100 %로 가정했다. 데이터는 평균±SEM을 나타낸다.
도 12, (a) 내지 (h). 단백질 및/또는 완충제로 세포를 처리한 후에, 공초점 현미경을 이용하여 세포에 의한 화합물의 흡수를 보여주는 사진을 찍은 것을 묘사한 것이다. (a) 인간 뇌종양 LN-229 세포를 20 μM의 미표지된 단백질 또는 PBS 완충제로 2시간 동안 선처리했고, 이후에 PBS 완충제로 세 번 세척했다. 모든 완충제를 버린 이후에 20 μM의 Alex568-Paz를 30분 동안 37 ℃에서 첨가했다. (b) 이후에, LN-229 세포를 20 μM의 미표지된 단백질 또는 PBS 완충제 및 20 μM의 Alex568-paz로 30분 동안 37 ℃에서 처리했다. (c) 인간 뇌종양 LN-229 세포의 다른 군을 10 μM의 미표지된 단백질 또는 PBS 완충제로 2시간 동안 선처리했고, 이후에 PBS 완충제로 세 번 세척했다. 모든 완충제를 버린 이후에 10 μM의 Alex568-Paz를 30분 동안 37 ℃에서 첨가했다. (d) 이후에, LN-229 세포를 10 μM의 미표지된 단백질 또는 PBS 완충제 및 10 μM의 Alex568-paz로 30분 동안 37 ℃에서 처리했다. (e) 인간 뇌종양 LN-229 세포를 20 μM의 미표지된 단백질 또는 PBS 완충제 및 20 μM의 Alex568-Paz로 30분 동안 37 ℃에서 처리했다. (f) 인간 뇌종양 LN-229 세포를 20 μM의 Alex568-H.8로 30분 동안 37 ℃에서 처리했다. (g) 인간 뇌종양 LN-229 세포를 20 μM의 Alex568-단백질로 30분 동안 37 ℃에서 처리했다. (h) 인간 유방선암 MCF-7 세포를 20 μM의 Alex568-단백질로 30분 동안 37 ℃에서 처리했다.
도 13, (a) 내지 (c). 펩타이드 결합과 세포 내로 진입하는 것을 묘사하는 그래프 및 도표이다. (a) UISO-Mel-2 또는 섬유아세포(3 x 105 세포)를 페놀레드 없이 MEME 배지 중에 현탁시켰다. Alexafluor 568이 결합된 p28(서열번호:13)을 10, 50, 100, 150, 250, 300 및 400 μM로 30, 60, 90 및 120초 동안 얼음 상에서 첨가함으로써 반응이 시작됐다. 세포를 유세포 분석기로 분석했다. (b) 펩타이드 농도(μM) 대 속도(MFI/초)로 그래프를 그려서 Km 및 Vmax를 계산했다. (c) 펩타이드 결합 및 주입은 모든 Mel2 세포(50,000 세포/ml)를 사용하여 결정되며, 1000 배 과잉의 미표지된 p28의 존재/부존재 하에서 방사선 동위원소로 표지된 아주린의 농도를 높여가며(0-175 mM) 또는 아주린의 농도를 높여가며 30 분 동안 37 ℃에서 배양되었고, 세포 펠렛내에 남아있는 방사능은 감마카운터를 사용하여 세어졌다. I125 아주린만 포함하여 배양된 세포 중의 방사능을 총 결합으로 가정했으며; 미표지된 아주린 또는 p28(서열번호:13)의 존재하에서 방사능을 비특이적 결합으로 가정했다. 총 결합에서 비특이적 결합을 뺌으로써 특이적 결합을 확인했고, 스캐차드조사구(scatchard plot)를 생성했다.
도 14, (a) 내지 (c). 흑색종 MEL-23 종양을 가지는 마우스에 p28(서열번호:13) 염료 복합물을 250 μL 중 60 μ몰랄 농도로 주입한 이후에, 그리고 (a) 대조군 PBS를 주입한지 24 시간 이후에 찍은 측면 및 등면 사진을 묘사한 것이고, (b) 대조군 PBS를 주입한 지 48 시간 이후에 찍은 측면 및 등면 사진을 묘사한 것이다. (c) 흑색종 MEL-23 종양을 가지는 마우스에 p28(서열번호:13)을 200 μM로 주입한 지 24 시간 및 48 시간 후에 찍은 측면 및 등면 사진을 묘사한 것이다.
도 15, (a) 내지 (c). 흑색종 MEL-23 종양을 가지는 마우스에 p18(서열번호:14)을 60 μM로 주입한 지 (a) 17 시간, (b) 24 시간, 및 (c) 46 시간 후에 찍은 측면 및 등면 사진을 묘사한 것이다. 또한, (c)는 p18(서열번호:14)을 주입한 지 46 시간 후에 심장, 폐, 간, 신장, 췌장, 및 뇌를 포함하는 마우스의 장기를 찍은 사진을 묘사한 것이다.
도 16, (a) 및 (b). (a) p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)를 60 μM로 주입한 지 12 시간 후에 찍은 마우스의 측면 및 등면 사진을 묘사한 것이다. (b) p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)를 주입한 지 12 시간 후에 찍은 마우스의 뇌를 포함하는 마우스의 장기의 측면 및 등면 사진을 묘사한 것이다.
도 17, (a) 및 (b). (a) 흑색종 MEL-6 종양을 가지는 마우스에 600 μM의 p18(서열번호:14) 및 arg-8(서열번호:3527)을 미정맥(tail vein)에 주입한 지 40 시간 후에 찍은 마우스의 측면 및 등면 사진을 묘사한 것이다. p18(서열번호:14)로 처리된 동물들은 50 만개의 세포를 수용했고, arg-8(서열번호:3527)로 처리된 동물들에서는 100 만개의 세포를 수용했다. (b) 600 μM의 p18(서열번호:14) 및 arg-8(서열번호:3527)을 주입한 지 40 시간 후에 마우스의 장기의 사진을 묘사한 것이다.
도 18, (a) 및 (b). (a) 흑색종 MEL-23 종양을 가지는 마우스에 60 μM의 p28(서열번호:13), p18(서열번호:14) 및 arg-8(서열번호:3527)을 주입한 지 16 시간 후에 찍은 마우스의 측면 및 등면 사진을 묘사한 것이다. (b) 흑색종 MEL-23 종양을 가지는 마우스에 60 μM의 p28(서열번호:13), p18(서열번호:14) 및 arg-8(서열번호:3527)을 주입한 지 24 시간 후에 찍은 마우스의 측면 및 등면 사진을 묘사한 것이다.
도 19. 흑색종 MEL-23을 가지는 마우스 안으로 60 μM의 p28(서열번호:13) 및 p18(서열번호:14) 염료를 주입한 지 48 시간 후에 찍은 마우스의 장기의 사진을 묘사한 것이다.
도 20. MEL-23 종양 및 장기를 가지는 마우스 안으로 60 μM의 p28(서열번호:13)을 주입한 지 24 시간 후에 찍은 마우스의 장기의 사진을 묘사한 것이다.
도 21. 60 μM의 p28(서열번호:13) 및 arg-8(서열번호:3527)을 주입한 지 16 시간 후에 찍은 흑색종 MEL-23을 가지는 마우스의 측면 및 등면 사진을 묘사한 것이다.
도 22. 60 μM의 p18(서열번호:14)을 주입한 지 16 시간 후에 찍은 흑색종 MEL-23을 가지는 마우스의 측면 및 등면 사진을 묘사한 것이다.
도 23. 240 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)로 고 투여량 처리한지 10 시간 및 24 시간 후에 찍은 종양을 가지는 마우스의 측면 사진을 묘사한 것이다.
도 24. 240 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)로 고 투여량 처리한지 28 시간 후에 찍은 MCF-7 종양을 가지는 마우스 및 장기들의 측면 및 등면 사진을 묘사한 것이다. 또한, 240 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)로 고 투여량 처리한지 28 시간 후에 찍은 MCF-7을 가지는 마우스의 사진을 묘사한 것이다.
도 25. 240 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)로 고 투여량 처리한지 50 시간 후에 찍은 종양을 가지는 마우스의 측면 및 등면 사진을 묘사한 것이다.
도 26. 120 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)을 HCT-116 종양 및 장기를 가지는 마우스의 미정맥 안으로 주입한지 24 시간 후에 찍은 마우스의 장기의 사진을 묘사한 것이다.
도 27, (a) 및 (b). (a) 120 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)을 HCT-116 종양 및 장기를 가지는 마우스의 미정맥 안으로 주입한지 24 시간 후에 찍은 마우스의 장기의 사진을 묘사한 것이다. (b) 120 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)을 미정맥 안으로 주입한지 21 시간 후에 HCT-116 종양을 가지는 마우스의 측면 사진을 묘사한 것이다.
도 28, (a) 및 (b). (a) 120 μM의 p28(서열번호:13)을 주입한지 24 시간 후에 HCT-116을 갖는 마우스의 측면 및 등면 사진을 묘사하며, 100 만개의 세포를 미정맥에 주입한지 47일 후에 HCT-116을 갖는 마우스의 측면 및 등면 사진을 묘사한 것이다. (b) 120 μM의 p28(서열번호:13)을 주입한지 4 시간 후에 HCT-116을 갖는 마우스로부터 찍은 마우스의 장기 사진을 묘사하며, 100 만개의 세포를 미정맥에 주입한지 47일 후에 HCT-116을 갖는 마우스의 장기 사진을 묘사한 것이다.
도 29. 120 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)로 처리한지 24 시간 후에 찍은 MEL-6 마우스의 장기의 사진을 묘사한 것이다.
도 30, (a) 및 (b). (a) 120 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527) 및 60 μM의 arg-8(서열번호:3527)을 주입한지 22 시간 후에 찍은 MEL-6 마우스의 측면 및 등면 사진을 묘사한 것이다. (b) 120 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527) 및 60 μM의 arg-8(서열번호:3527)로 처리한 후 MEL-6 마우스의 사진을 묘사한 것이다.
도 31, (a) 및 (b). (a) 60 및 120 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)로 처리한지 22 시간 후에 찍은 HT-1080 마우스의 장기의 사진을 묘사한 것이다. (b) 60 및 120 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)로 처리한지 22 시간 후에 찍은 HT-1080 마우스의 뇌 사진을 나란히 묘사한 것이며, 이는 뇌 안으로 p18(서열번호:14) 및 p28(서열번호:13)의 흡수 간의 차이점을 보여준다.
도 32. 60 및 120 μM의 18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)로 처리한지 16 시간 후에 가진 독소루비신(Doxorubicin) vs p28 연구 과정의 HT-1080 마우스의 측면 및 등면 사진을 묘사할 것이다.
도 33, (a) 및 (b). (a) 60 및 120 μM의 p28(서열번호:13) 및 arg-8(서열번호:3527)로 처리한 지 22 시간 후에 찍은 HT-1080 마우스의 장기의 사진을 묘사한 것이다. (b) 60 및 120 μM의 p28(서열번호:13) 및 arg-8(서열번호:3527)로 처리한 지 22 시간 후에 찍은 HT-1080 마우스의 뇌 사진을 나란히 묘사한 것이다.
도 34, (a) 및 (b). (a) 60 및 120 μM의 p18(서열번호:14) 및 arg-8(서열번호:3527)로 처리한 지 22 시간 후에 찍은 HT-1080 마우스의 장기의 사진을 묘사한 것이다. (b) 60 및 120 μM의 p18(서열번호:14) 및 arg-8(서열번호:3527)로 처리한 지 22 시간 후에 찍은 HT-1080 마우스의 뇌 사진을 나란히 묘사한 것이다.
도 35, (a) 내지 (e). 미정맥을 통해 처리된 폐 전이를 가지는 HT-1080의 사진을 묘사하는 것으로, (a) 복강 내에 3 mg/kg 독소루비신 3 회 처리; (b) 복강 내에 5 mg/kg p28 매일 주입; (c) PBS 대조군, 복강내에 매일 PBS 주입; (d) 복강 내에 10 mg/kg p28 매일 주입; (e) 복강 내에 매일 20 mg/kg 주입했다.
도 36, (a) 및 (b). (a) 1 x 106 세포가 미정맥 안으로 주입되고(43 일 동안), 모든 처리된 마우스는 폐 전이를 가지는 동물 연구에서, 60 μM의 p28(서열번호:13)을 미정맥 안으로 주입한 지 24 및 26 시간 후에 찍은 HT-1080 마우스의 장기의 사진을 묘사한 것이다. (b) 1 x 106 세포가 미정맥 안으로 주입되는(43 일 동안) 동물 연구에서, 60 μM의 p28(서열번호:13)을 미정맥 안으로 주입한 지 22 시간 후에 찍은 HT-1080 마우스의 측면 및 등면 사진을 묘사한 것이다. 동물 6982는 사진을 찍을 때 죽었었다.
도 37. 1 x 106 세포가 미정맥 안으로 주입되는(43 일 동안) 동물 연구에서, 60 μM의 p28(서열번호:13)을 미정맥 안으로 주입한 지 26 시간 후에 찍은 HT-1080 마우스의 측면 및 등면 사진을 묘사한 것이다.
도 38, (a) 및 (b). 60 및 120 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)로 처리된 지 12 시간 후에 찍은 (a) 마우스의 장기의 사진, (b) Balb-C 펩타이드 연구에서 마우스의 등면의 사진을 묘사한 것이다.
도 39, (a) 및 (b). 60 및 120 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)로 처리된 지 24 시간 후에 찍은 (a) 마우스의 장기의 사진, (b) Blab-C 펩타이드 연구에서 마우스의 측면 사진을 묘사한 것이다.
도 40. 미정맥 안으로 60 μM의 p18(서열번호:14) 및 arg-8(서열번호:3527)을 주입한 지 16 시간 후에 MEL-6 마우스(미정맥 안으로 50 만개의 세포가 주입됨)의 측면 및 등면 사진을 묘사한 것이다.
도 41, (a) 내지 (d). p18(서열번호:14) 및 p28(서열번호:13)로 처리된 후 마우스의 장기, 구체적으로 마우스의 뇌의 사진을 묘사한 것이다.
도 42. p28(서열번호:13), p18(서열번호:14) 및 arg-8(서열번호:3527)로 처리된 지 24 시간 후에 찍은 MEL-6의 장기의 사진을 묘사한 것이다.
도 43, (a) 내지 (c). (a) 60 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)로 처리된 지 3 시간 후에 MEL-6 마우스의 측면 및 등면 사진을 묘사한 것이다. (b) 60 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)로 처리된 지 22 시간 후에 MEL-6 마우스의 측면 및 등면 사진을 묘사한 것이다. (c) 60 μM의 p18(서열번호:14), p28(서열번호:13) 및 arg-8(서열번호:3527)로 처리된 지 24 시간 후에 MEL-6 마우스의 장기 사진을 묘사한 것이다.
도 44, (a) 및 (b). p18(서열번호:14) 및 p28(서열번호:13)을 (a) 마우스의 뇌 및 (b) 마우스의 장기에 흡수한 것을 묘사한 것이다.
도 45. 50 만개의 세포가 정맥 내 주입으로 미정맥에 주입하는 연구에서, 24 μM의 p18(서열번호:14) 및 arg-8(서열번호:3527)을 미정맥 안으로 주입한 지 120 시간 후에 찍은 MEL-6 마우스의 측면 및 등면 사진을 묘사한 것이다.
도 46. p18(서열번호:14)로 처리한 지 168 시간 후에 찍은 MEL-6 마우스의 장기의 사진을 묘사한 것이다,
도 47. arg-8(서열번호:3527) 및 p18(서열번호:14)을 주입한 지 72 시간 이후에 찍은 MEL-6 마우스의 측면 및 등면 사진을 묘사하고, 세포를 주입한 지 41 일 후에 찍은 MEL-6 마우스의 측면 및 등면 사진을 묘사한 것이다.
도 48. arg-8(서열번호:3527) 및 p18(서열번호:14)을 주입한 이후에 찍은 마우스의 등면 사진을 묘사한 것이다.
도 49. arg-8(서열번호:3527) 및 p18(서열번호:14)을 주입한 지 3, 24 및 48 시간 후에 찍은 마우스의 측면 및 정면 사진을 묘사한 것이다.
본 명세서에서 사용되는, 용어 "세포"는 본 명세서에서 특별히 "단일 세포"라고 하지 않는 한, 상기 용어의 단수 또는 복수 모두를 포함한다.
본 명세서에서, “폴리펩타이드”, “펩타이드”, 그리고 “단백질”이라는 용어는 아미노산 잔기의 중합체를 표기하기 위해 상호 교환적으로 사용되었다. 상기 용어는 하나 이상의 아미노산 잔기가 자연적으로 존재하는 아미노산에 대응되는 인공적인 화학적 유사체인 아미노산 중합체에 적용된다. 또한, 상기 용어는 자연적으로 존재하는 아미노산 중합체에도 적용된다. 또한, “폴리펩타이드”, “펩타이드”, 그리고 “단백질”이라는 용어는 글리코실화 반응, 지질 부착, 황산화, 글루탐산 잔기의 감마 카복실화, 수산화, 그리고 ADP-리보스화를 포함하지만 이에 제한되지 않는 변화를 의미한다. 폴리펩타이드가 항상 완전한 선형 구조로 존재하는 것은 아니라는 것이 인식될 것이다. 예를 들어, 폴리펩타이드는 유비퀴틴 표지의 결과로 분지 될 수 있으며, 자연적으로 발생하지 않는 인간에 의한 조작이 불러온 사건들과 자연적으로 발생하는 사건을 포함하는 단백질 번역 후 사건들의 결과로서 구형(가지를 포함하거나 포함하지 않는)을 띨 수 있다. 구형의, 가지를 띤, 그리고 가지를 띤 구형의 폴리펩타이드는 비-번역 자연적 과정에 의해 합성될 수 있으며, 완전히 인공적인 방법으로도 합성될 수 있다. 합성 펩타이드는 세포 성분의 도움없이 제조된 것이다. 펩타이드를 제조하기 위한 합성 방법은 당해 분야에 잘 알려지고, 상업적으로 사용가능하다. 나아가, 본 발명은 메티오닌을 함유하는 및 메티오닌을 함유하지 않는 본 발명의 단백질의 아미노 말단 변이체의 사용을 고려한다.
본 명세서에서 사용되는, 용어 "질환"은 살아있는 동물의 정상 상태의 장애를 구성하거나, 신체 기능의 수행을 교란하거나 변형하는 정상으로부터의 해부학적 및 생리학적 일탈을 포함한다.
본 명세서에서 사용되는, 용어 "세포 성장을 억제"는 세포 분열 및/또는 세포팽창을 늦추거나 중단시키는 것을 의미한다. 또한, 이 용어는 세포 발생의 억제 또는 세포 죽음을 증가시키는 것을 포함한다.
본 명세서에서 사용되는, 용어 "~고통받고 있는"은 질환의 증상을 현재 나타내는 것과, 관찰 가능한 증상 없이 질환을 가지는 것과, 질환으로부터 회복하는 것, 그리고 질환으로부터 회복한 것을 포함한다.
본 명세서에서 사용되는, 용어 "치료"라는 용어는 치료되고 있는 질환과 연관된 질환 또는 증상의 진행 또는 심각성을 막는 것, 낮추는 것, 멈추는 것, 또는 반전시키는 것을 포함한다. 그러한 맥락에서, "치료"라는 용어는 필요한 의료적, 치료적 및/또는 예방적 투여를 포함한다.
"치료적 유효량"은 치료받고 있는 피험자의 특정 질환의 나타나는 증상을 방지하거나, 낮추거나, 멈추게하거나 발달을 후퇴시키기 위한 유효량 또는 상기 특정 질환을 부분적으로 또는 완전히 완화시키기 위한 유효량이다. 치료적 유효량의 결정은 당해 분야의 기술자의 능력에 의한다.
본 명세서에서 사용되는, 용어 "약학적 활성"은 생물학적 시스템에 대한 약물 또는 다른 화학물질의 효과를 의미한다. 상기 화학물질의 효과는 이로울 수 있거나(치료적) 또는 해로울 수 있다(독성). 순수한 화학물질 또는 혼합물은 천연 유래 성분(식물, 동물 또는 미네랄)일 수 있거나, 합성 화합물일 수 있다.
본 명세서에서 사용되는, 용어 "전암성"는 전암증세를 의미하거나, 비정상세포가 통제되지 않고 분할되기 이전을 의미한다.
본 명세서에서 사용되는, 용어 "약물 동력학 성질"은 유기체 또는 숙주에서 활성제 또는 약물의 기질을 설명하는 파라미터(parameter)를 나타낸다. 대표적인 약물 동력학 성질은 혈장 반감기, 간의 제1단계 물질대사, 분포 용적, 알부민과 같은 혈청 단백질의 정도, 결합 등을 포함한다.
본 명세서에서 사용되는, 용어 "혈장 반감기"는 생물학적 과정, 예를 들어 생물학적 물질대사, 배출 등을 통해 환자의 혈장으로부터 투여된 약물이 반으로 제거되는 시간을 나타낸다.
본 명세서에서 사용되는, 용어 "분포 용적"은 유기체, 예를 들어 세포 내 및 세포 외 공간, 조직 및 장기 등의 다양한 구획 전반에 걸친 약물의 분포 및 지속 정도를 나타낸다. 이 인자는 약물이 신체 안에 분포되는 추정 부피인 "표면상의 분포 용적" 또는 Vd로서 나타내진다. 큰 값의 Vd는 상기 약물이 신체 전반에 걸쳐 더 넓게 분포 된다는 것을 시사하고, 더 적은 양의 약물이 혈장에 있으므로 제거 지점, 신장 및 간으로 전달될 것이기 때문에 이는 더 긴 반감기와 관련될 수 있다는 것을 시사한다.
본 명세서에서 사용되는, 용어 "혈청 결합의 정도"는 알부민과 같은 혈청 단백질에 의해 결합되는 약물의 경향을 나타낸다.
본 명세서에서 사용되는, 용어 "효능"은 특정 활성제의 의도된 목적에 대한 상기 활성제의 효과를 나타내며, 즉 주어진 활성제가 이의 약학적 효과를 유발하는 능력을 나타낸다.
본 명세서에서 사용되는, 용어 "특이적 활성"은 주어진 조건, 주어진 시간 동안 효소의 밀리그램 당 효소에 의해 형성된 산물의 양을 나타낸다. 특이적 활성은 반응 속도와 반응 부피를 곱하고, 이를 효소의 질량으로 나눈 것이다. 운반 펩타이드(transport peptide)의 경우에, 상기 특이적 활성은 주어진 조건, 주어진 시간 동안 운반 펩타이드 또는 운반 펩타이드-카르고 복합체의 밀리그램 당 세포 안으로 내재화된 수송 펩타이드 또는 수송 펩타이드-카르고 복합체의 양일 것이다.
본 발명의 단백질 또는 다른 세포 산물을 한정하기 위해 사용되는 경우에, 본 명세서에서 사용되는 용어 "실질적으로 순수한"은 예를 들어, 다른 단백질 및/또는 활성 억제 화합물이 실질적으로 없는 형태 또는 다른 것이 섞이지 않은 형태로 성장 배지 또는 세포의 함유물로부터 단리된 단백질을 나타낸다. 상기 용어 "실질적으로 순수한"은 단리된 분획의 적어도 약 75 %(건조중량) 또는 적어도 "75 % 실질적으로 순수함"을 나타낸다. 더 구체적으로, 용어 "실질적으로 순수한"은 적어도 약 85 %(건조중량)의 활성 화합물을 갖는 화합물을 나타내거나, "85 % 실질적으로 순수함"을 나타낸다. 매우 구체적으로, 용어 "실질적으로 순수한"은 적어도 약 95 %(건조중량)의 활성 화합물을 갖는 화합물을 나타내거나, 적어도 "95 % 실질적으로 순수함"을 나타낸다. 또한, 상기 용어 "실질적으로 순수한"은 합성 제조된 단백질 또는 화합물을 제한하기 위해 사용될 수 있으며, 예를 들어, 상기 합성 단백질은 합성반응의 시약 및 부산물로부터 단리된다.
본 발명의 펩타이드 또는 화합물을 나타내는 경우에, 본 명세서에서 사용되는 용어 "약학적 등급(pharmaceutical grade)"은 합성 시약 및 부산물을 포함하는 천연 상태로 발견되는 물질을 일반적으로 동반하는 구성 성분으로부터 실질적으로 또는 필수적으로 단리되는 펩타이드 또는 화합물, 그리고 약학적으로 이의 사용을 악화시키는 구성 성분으로부터 실질적으로 또는 필수적으로 단리되는 펩타이드 또는 화합물이다. 예를 들어, "약학적 등급" 펩타이드는 임의의 발암 물질로부터 단리되어 떨어져 있을 수 있다. 일부 예에서, 환자에게 정맥 내 투여가 부적합한 조성물이 되도록 하는 임의의 물질로부터 실질적으로 또는 필수적으로 단리되는 펩타이드 또는 화합물을 명시하기 위하여, "정맥 내 약학적 등급"과 같은 "약학적 등급"은 투여의 의도된 방법에 의해 수정될 수 있다. 예를 들어, "정맥 내 약학적 등급" 펩타이드는 SDS와 같은 용제 및 아자이드(azide)와 같은 항균제로부터 단리될 수 있다.
관용구 "단리된", "정제된" 또는 "생물학적 순수한"은 천연 상태로 발견되는 물질을 보통 동반하는 구성 성분을 실질적으로 또는 필수적으로 포함하지 않는 물질을 나타낸다. 따라서, 본 발명에 따른 단리된 펩타이드는 보통 당소(in situ) 환경에서 펩타이드와 연관된 물질을 함유하지 않는 것이 바람직하다. "단리된" 영역은 유래된 상기 영역으로부터 폴리펩타이드의 전체 서열을 포함하지 않는 영역을 나타낸다. "단리된" 핵산, 단백질 또는 이의 각각의 절편은 생체조건 환경에서 실질적으로 제거되어서, 숙련된 기술자에 의해 뉴클레오티드 서열분석, 제한효소절단, 부위 특이적 돌연변이, 및 핵산 절편에 대한 발현 벡터 안으로 서브클로닝(subcloning) 하는 것뿐만 아니라 실질적으로 순수한 양으로 단백질 또는 단백질 절편을 얻도록 다루어 질 수 있다.
본 명세서에서 사용되는 용어 "야생형"은 자연적으로 발생되는 펩타이드와 동일한 서열을 갖는 펩타이드를 나타낸다.
펩타이드에 관하여 본 명세서에서 사용되는 용어 "변이체"는 야생형 폴리펩타이드에 비해 치환되거나, 결손되거나, 삽입된 아미노산을 가질 수 있는 아미노산 서열 변이체를 나타낸다. 변이체는 야생형 펩타이드의 절단일 수 있다. "결손"은 야생형 단백질 내로부터의 하나 이상의 아미노산을 제거하는 것이며, 반면에 "절단"은 야생형 단백질의 하나 이상의 말단으로부터 하나 이상의 아미노산을 제거하는 것이다. 따라서, 변이체 펩타이드는 폴리펩타이드를 복사하는 유전자의 처리에 의해 제조될 수 있다. 변이체는 폴리펩타이드의 기본 조성물 또는 특징을 바꿈으로써 제조될 수 있지만, 적어도 폴리펩타이드의 기본적인 약학적 활성의 일부를 바꾸지 않는다. 예를 들어, 녹농균 운반 펩타이드의 "변이체"는 암세포에 진입하는 능력을 보유하는 돌연변이된 녹농균 운반 펩타이드일 수 있다. 일부 경우에서, 변이체 펩타이드는 ε-(3,5-디니트로벤조일)-Lys 잔기와 같은 비-천연 아미노산으로 합성된다(Ghadiri & Fernholz, J. Am. Chem. Soc., 112:9633-9635 (1990)). 일부 실시예에서, 상기 변이체는 야생형 펩타이드 또는 이의 일부분에 비해, 치환되거나, 결손되거나, 삽입된 아미노산이 20개, 19개, 18개, 17개 또는 16개를 넘지 않는다. 일부 실시예에서, 상기 변이체는 야생형 펩타이드 또는 이의 일부분에 비해, 치환되거나, 결손되거나, 삽입된 아미노산이 15개, 14개, 13개, 12개 또는 11개를 넘지 않는다. 일부 실시예에서, 상기 변이체는 야생형 펩타이드 또는 이의 일부분에 비해, 치환되거나, 결손되거나, 삽입된 아미노산이 10개, 9개, 8개 또는 7개를 넘지 않는다. 일부 실시예에서, 상기 변이체는 야생형 펩타이드 또는 이의 일부분에 비해, 치환되거나, 결손되거나, 삽입된 아미노산이 6개를 넘지 않는다. 일부 실시예에서, 상기 변이체는 야생형 펩타이드 또는 이의 일부분에 비해, 치환되거나, 결손되거나, 삽입된 아미노산이 5개 또는 4개를 넘지 않는다. 일부 실시예에서, 상기 변이체는 야생형 펩타이드 또는 이의 일부분에 비해, 치환되거나, 결손되거나, 삽입된 아미노산이 3개, 2개 또는 1개를 넘지 않는다.
본 명세서에서 사용된 용어 "아미노산"은 임의의 자연적으로 발생 또는 비-자연적으로 발생된 아미노산 잔기 또는 합성된 아미노산 잔기, 즉 적어도 하나의 카복실기 및 1개, 2개, 3개 이상의 탄소 원자, 보통 하나의(α) 탄소 원자에 결합된 적어도 하나의 아미노 잔기를 포함하는 부분을 포함하는 아미노산 부분을 의미한다. 아미노산은 아미노산의 L-이성질체 또는 D-이성질체일 수 있다.
본 명세서에서 사용된 용어 "변형된 잔기"는 본 명세서에 개시되는 하나 이상의 방법 및 기술을 포함할 수 있지만 이에 제한되지 않는 방법 또는 기술을 사용하여 변형되는 아미노산을 나타낸다.
펩타이드와 관련하여 본 명세서에 사용된 용어 "유도체"는 연구 대상 펩타이드로부터 유래된 펩타이드를 나타낸다. 유도체는 펩타이드가 이의 기본적인 약학적 활성의 일부를 여전히 보유하는 펩타이드의 화학적 변형을 포함한다. 예를 들어, 녹농균 운반 펩타이드의 "유도체"는 암세포에 진입하는 능력을 보유하는 화학적으로 변형된 녹농균 운반 펩타이드이다. 관심이 있는 화학적 변형은 펩타이드의 아미드화, 아세틸화, 황산화, 폴리에틸렌 글리콜(PEG) 변형, 인산화 또는 글리코실화를 포함하지만 이에 제한되지 않는다. 게다가, 유도체 펩타이드는 화합물에 폴리펩타이드가 융합된 것일 수 있으며, 상기 화합물의 예는 다른 펩타이드, 약물 분자 물질, 다른 치료적 물질, 약학적 물질 또는 검출가능한 프로브(probe)가 있지만 이에 제한되지 않는다.
용어 "퍼센트(%) 아미노산 서열 동일성"은 두 개의 아미노산 서열을 나란히 놓는 경우에, 후보 서열(candidate sequence)의 아미노산 잔기와 동일한 폴리펩타이드의 아미노산 잔기의 퍼센트로서 정의된다. % 아미노산 동일성을 결정하기 위하여, 서열을 나란히 놓고, 만일 필요하다면, 최대 %의 서열 동일성을 얻기 위해 간격을 두며; 보존적 치환은 서열 동일성의 일부로서 고려되지 않는다. 퍼센트 동일성을 결정하기 위해 아미노산 서열을 나란히 놓는 과정은 당해 분야의 기술자에게 잘 알려져 있다. 종종 공개적으로 사용가능한 컴퓨터 소프트웨어 예를 들어, BLAST, BLAST2, ALIGN2 또는 Megalign(DNASTAR) 소프트웨어가 펩타이드 서열을 나란히 놓기 위해 사용된다. 구체적인 실시예에서, 긴 복잡한 필터, 예상(expect) 10, 글자크기 3, 존재(existence) 11 및 연장(extension) 1의 디폴트 파라메터를 사용하는 Blastp(Bethesda MD의 National Centor for Biothechnology Information에서 공급함)가 사용된다.
아미노산 서열이 나란히 놓이면, 주어진 아미노산 서열 B에, B와 함께 또는 B에 대하여 주어진 아미노산 서열 A의 % 아미노산 서열 동일성(주어진 아미노산 서열 B에, B와 함께 또는 B에 대하여 특정 % 아미노산 서열 동일성을 갖는 주어진 아미노산 서열 A로 또한 표현될 수 있음)은:
% 아미노산 서열 동일성 = X/Y * 100
으로 계산될 수 있으며,
상기 X는 서열 얼라인먼트(alignment) 프로그램 또는 A와 B의 알고리즘 얼라인먼트에 의한 동일한 매치(match)로서 점수 매겨졌고, Y는 B의 아미노산 잔기의 총 수이다.
만일 아미노산 서열 A의 길이가 아미노산 서열 B의 길이와 동일하지 않으면, B에 대한 A의 % 아미노산 서열 동일성은 A에 대한 B의 % 아미노산 서열 동일성과 같지 않을 것이다. 만일 더 긴 서열을 더 짧은 서열에 비교하면, 더 짧은 서열은 "B" 서열일 것이다. 예를 들어, 만일 절단된 펩타이드를 상응하는 야생형 폴리펩타이드에 비교하면, 상기 절단된 펩타이드는 "B" 서열일 것이다.
일반
본 발명은 큐프레독신의 하나 이상의 약학적 활성을 유지하는 큐프레독신 유래 펩타이드와 관련이 있고, 상기 큐프레독신 유래 펩타이드는 약물 동력학 성질 중 안정성, 특이적 활성, 혈류 중의 반감기를 개선했으며, 및/또는 면역원성을 감소시키는 것과 같이 약물 동력학 성질을 개선했다. 게다가, 본 발명은 변형된 큐프레독신 유래 펩타이드로부터 유래된 화합물에 관한 것이며, 상기 화합물은 큐프레독신의 하나 이상의 약학적 활성을 유지하고 약물 동력학을 개선했다. 마지막으로, 본 발명은 다양한 질환을 앓는 포유류 환자를 치료 및/또는 진단하기 위해서, 그리고 다양한 질환을 앓는 포유류 환자를 조사하기 위해서 변형된 큐프레독신 유래 펩타이드 및 이로부터 제조된 화합물을 사용하는 방법에 관한 것이다. 본 명세서에 함께 제출되는 서열 목록은 전체가 본 명세서에 참조로 포함된다.
조성물
본 발명은 큐프레독신 유래 펩타이드의 변형물인 펩타이드에 관한 것이다. 일부 실시예에서 상기 변형된 펩타이드는 약물 동력학 성질을 개선했다. 일부 실시예에서, 이러한 변형된 큐프레독신 유래 펩타이드는 큐프레독신의 적어도 하나의 약학적 활성을 보유한다. 일부 실시예에서, 상기 변형된 큐프레독신 유래 펩타이드는 단리되거나, 실질적으로 순수하거나, 약학적 등급으로 분류된다. 구체적 실시예에서, 상기 변형된 큐프레독신 유래 펩타이드는 정맥 내 약학적 등급이다.
큐프레독신, 구체적으로 녹농균으로부터 유래된 아주린은 포유류 환자를 치료 및/또는 진단하기에 유용하고, 질환을 앓는 포유류 환자에 대한 조사를 하기에 유용한 몇몇 유용한 약학적 활성을 가진다고 알려져 있다. 예를 들어, 녹농균 아주린과 같은 수많은 큐프레독신 단백질은 특이적으로 진입하여 많은 종류의 포유류 암세포를 죽이는 능력을 가진다. 문헌[Yamada 등, Cell. Biol. 7:1418-1431 (2005)]; 문헌[Hiraoka 등, PNAS 101 :6427-6432 (2004)]; 문헌[Hiraoka 등, Biochem. Biophys. Res. Comm. 338:1284-1290 (2005)]; 2005년 10월 6일에 출원된 미국특허 출원번호 11/244,105; 2003년 11월 24일에 출원된 미국특허 출원번호 10/720,603; 2002년 1월 15일에 출원된 미국특허 출원번호 10/047,710; 2006년 7월 13일에 출원된 미국특허 출원번호 11/485,252, 모든 문헌은 전체가 참조로 본 명세서에 포함된다. 또한, 녹농균으로부터 유래된 아주린은 바이러스 또는 세균 감염, 더 구체적으로 말초혈액 단핵 세포 중의 HIV-1 감염의 증가를 억제하는 것으로 알려져 있고, 말라리아에 감염된 포유류 적혈구의 기생충혈증도 억제한다고 알려져 있다. 문헌[Chaudhari 등, Cell Cycle. 5:1642-1648 (2006)]; 2006년 5월 19일에 출원된 미국특허 출원번호 11/436,591; 2006년 5월 19일에 출원된 미국특허 출원번호 11/436,590, 이들 문헌 모두 전체가 참조로 본 명세서에 포함된다. 또한, 녹농균으로부터 유래된 아주린은 다양한 포유류 세포 및 조직에서 에프린 신호전달계를 교란하는 것으로 알려져 있다. 2006년 5월 19일에 출원된 미국특허 출원번호 11/,436,592, 이 문헌은 전체가 참조로 본 명세서에 포함된다. 나아가, 녹농균 아주린으로부터 유래된 펩타이드는 포유류 세포의 혈관 생성, 구체적으로 인간 제대 맥관 표피 세포(HUVECs)를 억제하는 것으로 알려져 있다. 2006년 7월 19일에 출원된 미국특허 출원번호 11/488,693, 이 문헌은 전체가 본 명세서에 참조로 포함된다. 일부 실시예에서, 본 발명의 변형된 큐프레독신 유래 펩타이드는 그들이 유래된 것으로부터 큐프레독신의 적어도 하나의 약학적 활성을 보유한다. 큐프레독신의 약학적 활성은 큐프레독신의 어떤 유용한 활성일 수 있다. 특히 관심이 있는 약학적 활성은 포유류 암세포에 특이적으로 진입하는 능력, 비-암성 포유류 세포에 진입하지 않는 능력, 전암성 포유류 세포에 진입하는 능력, 포유류 암세포를 죽이는 능력, 전압성 포유류 세포를 죽이는 능력, 바이러스 또는 세균 감염의 증가를 억제하는 능력, 말초 혈관 단핵 세포 중의 HIV-1 감염을 억제하는 능력, 말라리아에 감염된 적혈구에서 말라리아에 의한 기생충혈증을 억제하는 능력, 구체적으로 HUVECs를 포함하지만 이에 제한되지 않는다. 펩타이드의 약학적 활성의 양을 측정하는 방법은 상기 참조된 출원서 및 공개서에서 제공된다.
녹농균으로부터 유래된 큐프레독신인 아주린은 단백질 전달 물질(PTD)을 인간 암세포에 선택적으로 진입시키기 위해 활용한다. 이러한 큐프레독신에 의해 사용되는 최소의 모티프(motif) PTD는 이전에 확인되지 않았었다. 아주린, p18(서열번호:14) 및 p28(서열번호:13)에 의한 진입 메커니즘은 여기에 구체적으로 설명되고 하기에서 실시예로 제공된다. 일반적으로, PTDs는 이들의 구조적 특성에 기초하여 두개의 군으로 모이며, 이러한 두 개의 군은 양이온 잔기 또는 양친매성 α-나선이지만, 여러 개의 PTD가 두 개의 군에 모두 포함될 수 있다. 일반적으로, 양이온 펩타이드는 처음에 당단백질의 음이온으로 하전된 표면에 결합함으로써 원핵생물 종 및 진핵생물 종의 세포막과 상호 작용하여, 정상 및 악성 세포주의 넓은 범위 내로 효과적인 진입을 가능하게 한다(Kondejewski, L. H., 등, J Biol Chem 277:67-74 (2002); Fuchs, S.M. 및 Raines, R.T., Biochemistry, 43:2438-2444 (2004)). HS에 양이온 펩타이드가 결합하는 것은 HS에 대한 이들의 높은 친화성(Kd -109 nM)과 일치하며, 아주린, p18(서열번호:14) 및 p28(서열번호:13)에 대해 보고된 값을 훨씬 넘는다(Tran, D. 등, Proc Natl Acad Sci USA 84: 7957-7961 (1987)).
반면에, 합성한, 양이온의, 양친매성의 α-나선 부분입체이성질성 펩타이드에 의해 미치는 세포독성 효과는 암세포에 일반적으로 특이적이지 않다. 암세포를 세포 융해하는 양친매성 세포 침투성 펩타이드(CPPs)는 암세포막을 교란하여 미토콘드리아의 투과성을 바꾸거나, 특정 수용체 매개 메커니즘을 통해 작용한다(Leuschner, C. 및 Hansel, W., Curr Pharm Des, 10: 2299-2310 (2004)). Lys, Ala 및 Leu 잔기만으로 구성되는 것을 포함하는 펩타이드의 합성 메가이닌(megainin), 선형의, 나선의, 채널 형성 또는 이온 투과 담체 부류는 정상 세포에 대한 세포독성보다 낮은 투여량에서 조혈 목표 세포 및 견고한 종양 목표 세포를 신속하게 그리고 비가역적으로 용해한다(Javapour, M. M., 등, J Med Chem, 39:3107-3113 (1996); Cruciani, R.A., 등, Proc Natl Acad Sci USA 88:3792-3796 (1991); Papo, N. 및 Shai, Y., Biochemistry, 42:9346-9354 (2003)). 또한, 림프의 그리고 종양의 혈관에 대해 상당히 특이적이지만, 파지-디스플레이 기술을 통해 생성된 펩타이드는 암세포의 직접 침투에 의해 세포 독성을 유도하지 않는다.
이와 대조적으로, 아주린 및 p28(서열번호:13)과 p18(서열번호:14)로부터 유래된 두 개의 펩타이드는 우선적으로 암세포에 침투하여 세포 증식 억제 및 세포독성 메커니즘을 통해 이들의 확산을 억제하는 특별한 성질을 보유한다. 이는 p18(서열번호:14)이 인간 암세포 안으로 아주린의 우선적 진입에 대한 원인이 되는 최소 모티프라는 것을 공초점 현미경 및 FACS에 의해 보여졌다.
암세포에 진입하는 것 외에, p18(서열번호:14) 및 p28(서열번호:13)은 실시예 9에서 개시된 방법을 사용하여 얻은 도 14 내지 도 49에서 보여지는 종양 및 포유류의 장기에 진입할 수 있다. 또한, 놀랍게도, p18(서열번호:14) 및 p28(서열번호:13)은 도 16a, 16b, 17b, 19, 20, 24, 26, 27a, 28b, 29, 30b, 31a-b, 33a-c, 34a-c, 36a, 38a, 39a, 41a-d, 42, 43b, 44a-b 및 46에서 예로 증명되는 것처럼, 혈액 뇌 관문을 침투하고 포유류의 뇌에 진입할 수 있다. 아주린과 같은 산화환원 단백질은 일반적으로 CPPs 또는 항증식제로 분류되지 않는다. 양친매성, 아주린 절편 p18(서열먼호:14) 및 p28(서열번호:13)은 아주린의 54번 내지 67번 아미노산 α-나선 구조를 함유할 뿐만 아니라 부분적인 β-시트 구조를 함유하고, 암세포 진입 및 순환 억제 활성 각각에 대한 최소 서열을 말해준다. 아주린, p28(서열번호:13) 및 p18(서열번호:14)의 진입은 양이온 CPPs의 진입과 구별된다. 인테그린과 카데린을 포함하는 몇몇의 세포 표면 수용체 상에서 잘못된 N-글리코실화는 암의 다양한 조직발생의 진행과 전이의 변화와 연관이 있으며, 이는 아주린, p18(서열번호:14) 및 p28(서열번호:13) 침투의 최초 단계에서 아직 알려지지 않은 N-글리코실화 세포 표면 단백질의 역할을 시사한다(Partridge, E.A., 등, Science 306: 120-124 (2004); Seales, E.C., 등, Cancer Res 65:4645-4652 (2005)).
세포 침투를 위한 엔도시토시스 성분을 지원하는 양이온 CPPs의 온도 의존성 진입은 아주린 및 아미노산 절편 50번 내지 77번(p28, 서열번호:13)의 진입을 나타낸다(Yamada, T., 등, Cell Microbiol 7: 1418-1431 (2005)). 정상 및 악성 세포 안으로 아주린의 아미노산 50번 내지 67번(p18, 서열번호:14)의 진입은 p28(서열번호:13)에 비하여 가속화된 것을 보인다. p18(서열번호:14)의 더 낮은 Km 및 더 높은 Vmax는 아주린의 실제 PTD를 더 근접하게 보여주는 인지질막과 관련되는 경우에 아미노산 50번 내지 67번이 양친매성 구조를 분명히 나타낸다는 것을 시사한다. 반면에, 에너지 의존성 엔도시토시스 또는 기공과 관련된 과정은 이러한 펩타이드에 사용가능한 유일한 진입 메커니즘으로 보여지지 않는다. 예를 들어, 물질 대사와 막 전위 억제 나트륨 아자이드 및 양이온 펩타이드의 진입을 억제하는 와베인(ouabain)(Na+ K+ ATPase inhibitor)은 UISO-Mel-2 세포 또는 섬유아세포(도 10 b,c) 안으로 p18(서열번호:14) 또는 p28(서열번호:13) 중 어느 하나의 진입을 악화시켰으며, 이는 상기 펩타이드 중 어느 하나가 세포막에 직접적으로 침투할 수 있다는 것을 시사한다.
p18(서열번호:14), p28(서열번호:13) 및 아주린은 원형질 막을 침투하여 디나민에 독립적이고 클라트리닌에 의존적인 담체 매개 수단으로 생각되는 포낭과 연관된 후기 엔도솜, 리소솜 및 골지에 도달한다(Kirkham, M. 및 Parton, R.G., Biochem Biophys Acta 1746:349-363 (2005)). 포낭 운반 및 포낭 매개 엔도시토시스를 교란하는 노코다졸(nocodazole)은 50 내지 65 %로 침투를 억제했다. 노코다졸에 의한 침투의 현저한 억제 및 액틴 필라멘트를 교란하는 시토칼라신-D에 의한 상대적으로 부족한 억제는 포낭이 매개된 진입을 지지한다. 특히, 스타우로스포린의 부족한 효과는 디아민이 펩타이드의 침투에서 큰 역할을 하지 않는다는 것을 증명한다. Id. 이런 진입 경로는 내제성 세포 표면 성분 및 외관상으로 이질적인 분자, 즉 덱스트란에 대해 설명하고, 또한 전형적인 엔도시토시스 경로를 건너뛰기 위해 포낭을 활용하는 광범위한 병원균 또는 이들의 산물에 대해 설명한다. 지질 라프트(raft)를 교란하기 위한 β-메틸실로덱스트란, 필리핀(filipin) 또는 니스타틴(nystatin)을 갖는 원형질 막으로부터 콜레스테롤을 감소시킴으로써, 분리막 성분과 구획 막(compartmentalize membrane)에 유체 플랫폼(platform)을 제공하는 원형질 막은 UISO-Mel-2 세포와 섬유아세포(각각 35 % 및 42 %) 안으로 p18(서열번호:14)(50 %) 및 p28(서열번호:13)(~60 %)의 침투를 현저히 억제했으며, p18(서열번호:14) 및 p28(서열번호:13)의 현저한 퍼센트(~60 %)가 포낭을 통해 원형질 막을 침투한다는 것을 증명한다. 포낭은 신호 전달의 조절기로서 기능하는 카베올린 특이 단백질(카베올린-1, -2 또는 -3)의 존재에 의해 정의된 원형질 막의 지질 라프트 함입의 일부가 50 내지 100 nm인 오메가 형상을 가진다. 브레펠딘 A는 골지체를 교란하고 p18(서열번호:14)의 축적을 억제해서, 이런 경로가 p18(서열번호:14) 및 p28(서열번호:13) 진입에도 활용되고 세포 내 수송에도 활용된다는 결론을 가져온다. 포낭을 통한 p18(서열번호:14) 및 p28(서열번호:13)의 세포 침투는 N-글리코실화의 억제제가 UISO-Mel-2 세포에서 세포 진입을 ~60 %로 감소시키고, 섬유아세포에서 각각 25 %와 35 %로 감소시킨다는 증거와 잘 맞는다. p18(서열번호:14) 및 p28(서열번호:13) 진입 사이의 퍼센트 차이는 암 세포 대 정상 세포의 N-글리코실화 막 구조의 수, 그리고 이 메커니즘을 통해 p28(서열번호:13) 및 p18(서열번호:14)의 상대적 진입 경로와 관련이 있다.
아주린, p28(서열번호:13) 및 p18(서열번호:14) 모두는 수많은 다른 가능한 항암 펩타이드에 비해 높은 친화성 및 높은 용량으로 암세포에 결합한다. 결합 후에, 이 단백질/수용체 복합체는 포낭에 배치되고 국재화되며, 최후에는 골지, ER 및 핵으로 (카베오좀을 통해) 이동한다. 또한, 포낭-매개 진입 이외에, 운동 역학적 분석은 p28(서열번호:13) 및 p18(서열번호:14)이 비-클라트린 포낭 매개 과정을 통해 원형질 막을 침투한다는 것을 증명한다. 클라트린- 및 카베올린-독립 경로는 인터루킨 2 수용체 및 특정 글리코실-포스파티딜이노시톨(GPI)-닻형(anchored) 단백질에 대하여 구성요소의 내재화 메커니즘으로 존재할 수 있다(Lamaze, C, 등, Mol Cell 7:661-671 (2001); Sabharanjak, S., 등, Dev Cell, 2:411-423 (2002)). 또한, 클라트린- 및 카베올린-독립 엔도시토시스는 쥣과 폴리오마 바이러스에는 배타적으로 세포에 침투하거나 인플루엔자 바이러스의 경우에는 통상의 경로의 조합으로 세포에 침입하기 위한 병원균에 의해 사용된다(Ewers, H., 등, Proc Natl Acad Sci USA 102:15110-15115 (2005); Sieczkarski, S.B. 및 Whittaker, G.R., J Virol, 76:10455-10464 (2002)). 암세포에서 정상세포를 넘어서는 카베올린-1 발현의 증가가 암세포 안으로 아주린, p28(서열번호:13) 및 p18(서열번호:14)의 우선적인 진입에 대한 단 하나의 이유일 리가 만무하다. 또한, 섬유아세포 및 다수의 다른 정상세포는 이들의 표면상에 현저한 수의 포낭을 가진다.
p18(아주린의 아미노산 50번 내지 67번, 서열번호:14) 및 p28(아주린의 아미노산 50번 내지 77번, 서열번호:13)은 세포막 글리코스아미노글리칸에 의해 결합되지 않고, 엔도시토시스, 카베오좀 유도 경로 및 카베오좀 독립 경로를 통해 암세포를 우선적으로 침투한다. 상기 p18(서열번호:14) 및 p28(서열번호:13)의 세포 침투는 암세포에 대한 선호에 있어서 모든 현재의 CPPs에 관하여 특별하다. 놀랍게도, p28(서열번호:13)의 C-말단으로부터 10번 내지 12번 아미노산은 세포 순환 억제 및 세포사멸 활성/세포독성에 원인이 되는 도메인을 포함한다는 것을 보여준다. 나아가, 상기 도메인은 세포막 상의 특정 잔기에 접촉할 수 있어서, 진입을 허용하며; 특히 아주린의 69번, 70번, 75번, 76번 및 85번 아미노산은 세포막에 대한 접촉을 제공한다. 일단 내재화되면, p28(서열번호:13)은 세포분열 메커니즘을 통해 최초로 암세포 증식을 억제한다. 따라서, p18(서열번호:14) 및 p28(서열번호:13)이 인간 암세포 안으로 아주린의 우선적 진입 및 인간 암세포에 대한 아주린의 항-증식 활성의 상당한 양을 각각 설명한다고 현재 알려져 있다.
큐프레독신 유래 펩타이드는 임의의 큐프레독신, 또는 큐프레독신의 변이체, 유도체 또는 구조적 등가물, 또는 이의 절단일 수 있다. 일부 실시예에서, 상기 큐프레독신 유래 펩타이드는 상기 큐프레독신의 적어도 하나의 약학적 활성을 보유한다. 일부 실시예에서, 상기 큐프레독신은 아주린, 플라스토시아닌, 루스티시아닌, 슈도아주린, 오라시아닌 또는 아주린 유사 단백질일 수 있지만, 이에 제한되지 않는다. 상기 큐프레독신 유래 펩타이드는 녹농균, 포르미디움 라미노섬, 티오바실러스 페로옥시단스, 아크로모박터 시클로클라스테스, 슈도모나스 시린게, 수막구균, 장염비브리오균, 보데텔라 브론키셉티카, 보르데텔라 백일해균, 클로로플렉서스 오란티아쿠스 및 임균을 포함하는 임의의 유기체로부터 유래된 것일 수 있지만 이에 제한되지 않는다. 일부 실시예에서, 상기 큐프레독신은 아주린일 수 있으며, 구체적으로 녹농균, 슈도모나스 시린게, 임균, 장염 비브리오균 또는 보르데텔라 브론키셉티카를 포함하는 유기체로부터 유래되는 아주린일 수 있지만, 이에 제한되지 않는다.
큐프레독신 유래 펩타이드는 큐프레독신의 임의의 변이체, 유도체 또는 구조적 등가물일 수 있다. 일부 실시예에서, 상기 큐프레독신 유래 펩타이드는 큐프레독신의 절단일 수 있다. 또한, 상기 큐프레독신 유래 펩타이드는 당해 분야에 알려지고/알려지거나 선행하는 출원서에서 설명되는 임의의 큐프레독신 펩타이드 일수 있으며, 선행하는 출원서는 2005년 10월 6일에 출원된 미국특허 출원번호 11/244,105; 2003년 11월 24일에 출원된 미국특허 출원번호 10/720,603; 2002년 1월 15일에 출원된 미국특허 출원번호 10/047,710 그리고 현재는 등록된 미국특허 제7,084,105호; 2006년 7월 13일에 출원된 미국특허 출원번호 11/485,252; 2006년 5월 19일에 출원된 미국특허 출원번호 11/436,591; 2006년 5월 19일에 출원된 미국특허 출원번호 11/436,590; 2006년 5월 19일에 출원된 미국특허 출원번호 11/436,592; 및 2006년 7월 19일에 출원된 미국특허 출원번호 11/488,693이 있다. 상기 모든 출원서는 전체가 참조로 본 명세서에 포함된다. 일부 실시예에서, 상기 펩타이드는 단리된다. 일부 실시예에서, 상기 펩타이드는 실질적으로 순수하거나 약학적 등급이다. 다른 실시예에서, 상기 펩타이드는 펩타이드를 포함하거나, 펩타이드를 필수적 구성요소로 포함하는 조성물의 형태이다. 또 다른 구체적인 실시예에서, 상기 펩타이드는 포유류, 더 구체적으로 인간의 면역 반응을 발생시키지 않는다.
큐프레독신 유래 펩타이드는 야생형 큐프레독신에 비해 치환되거나, 결손되거나 삽입된 아미노산을 갖는 아미노산 서열 변이체일 수 있다. 이러한 변이체는 야생형 큐프레독신의 절단일 수 있다. 일부 실시예에서, 아미노산은 비-천연 또는 변형된 아미노산으로 치환될 수 있다. 비-천연 아미노산은 20개의 보통의 아미노산과 다른 것이다. 상기 큐프레독신 유래 펩타이드는 전체 길이의 야생형 폴리펩타이드보다 짧은 큐프레독신의 도메인을 포함한다. 일부 실시예에서, 상기 큐프레독신 유래 펩타이드는 약 10개의 잔기, 약 15개의 잔기 또는 약 20개의 잔기 보다 많은 잔기를 갖는 절단된 큐프레독신을 포함한다. 일부 실시예에서, 상기 큐프레독신 유래 펩타이드는 약 100개의 잔기, 약 50개의 잔기, 약 40개의 잔기, 약 30개의 잔기 또는 약 20개의 잔기 이하의 잔기를 갖는 절단된 큐프레독신을 포함한다. 일부 실시예에서, 큐프레독신은 상기 큐프레독신 유래 펩타이드를 가지며, 더 구체적으로 서열번호:1 내지 서열번호:12에 적어도 약 70 % 아미노산 서열 동일성, 적어도 약 80 % 아미노산 서열 동일성, 적어도 약 90 % 아미노산 서열 동일성, 적어도 약 95 % 아미노산 서열 동일성 또는 적어도 약 99 % 아미노산 서열 동일성을 가진다.
구체적인 실시예에서, 상기 큐프레독신 유래 펩타이드는 녹농균 아주린 잔기 50번 내지 77번(서열번호:13), 아주린 잔기 50번 내지 67번(서열번호:14) 또는 아주린 잔기 36번 내지 89번(서열번호:16)을 포함한다. 다른 실시예에서, 큐프레독신의 변이체는 녹농균 아주린 잔기 50번 내지 77번(서열번호:13), 아주린 잔기 50번 내지 67번(서열번호:14) 또는 아주린 잔기 36번 내지 89번(서열번호:16)으로 구성된다. 다른 구체적인 실시예에서, 상기 변이체는 아주린 외에 큐프레독신의 동등한 잔기로 구성된다. 또 다른 큐프레독신의 동등한 잔기를 확인하기 위하여, 연구 대상 큐프레독신 아미노산 서열은 BLAST, BLAST2, ALIGN2 또는 Megalign(DNASTAR)를사용하여 녹농균 아주린 서열에 나란히 놓여지며, 관련 있는 잔기는 녹농균 아주린 아미노산 서열상에 두었고, 동등한 잔기는 연구 대상 큐프레독신 서열상에서 찾았고, 이런 방식으로 동등한 펩타이드를 설계했다. 본 발명의 일 실시예에서, 큐프레독신 유래 펩타이드는 클로로플렉서스 오란티아쿠스(서열번호:21)의 오라시아닌 B 중 적어도 57번 내지 89번 아미노산을 포함한다. 본 발명의 또 다른 실시예에서, 큐프레독신 유래 펩타이드는 슈도모나스 시린게 아주린(서열번호:27) 중 적어도 51번 내지 77번 아미노산을 포함한다. 본 발명의 또 다른 실시예에서, 큐프레독신 유래 펩타이드는 수막구균 Laz(서열번호:23) 중 적어도 89번 내지 115번 아미노산을 포함한다. 본 발명의 또 다른 실시예에서, 큐프레독신 유래 펩타이드는 장염비브리오균(서열번호:28) 중 적어도 52번 내지 78번 아미노산을 포함한다. 본 발명의 또 다른 실시예에서, 큐프레독신 유래 펩타이드는 보르텔라 브론키셉티카(서열번호:29) 중 적어도 51번 내지 77번 아미노산을 포함한다. 또한, 상기 큐프레독신 유래 펩타이드는 자연적으로 발생하지 않는 합성 아미노산으로 구성되는 펩타이드를 포함한다. 예를 들어, 비-천연적으로 발생하는 아미노산은 혈류 중의 조성물의 반감기를 연장하거나 최적화하기 위하여 변이체 펩타이드 안으로 통합될 수 있다. 이러한 변이체는 D,L-펩타이드(부분입체이성질체), (예를 들어, Futaki 등, J. Biol. Chem. 276(8):5836-40 (2001); Papo 등, Cancer Res. 64(16):5779-86 (2004); Miller 등, Biochem. Pharmacol. 36(1):169-76, (1987) 참조); 흔치 않은 아미노산을 함유하는 펩타이드(예를 들어, Lee 등, J. Pept. Res. 63(2):69-84 (2004) 참조), 올레핀을 함유하는 비-천연 아미노산 이후에 탄화수소 봉합(예를 들어, Schafmeister 등, J. Am. Chem. Soc. 122:5891-5892 (2000); Walenski 등, Science 305:1466-1470 (2004) 참조), 및 ε-(3,5-디니트로벤조일)-Lys 잔기를 포함하는 펩타이드를 포함하지만, 이에 제한되지 않는다.
다른 실시예에서, 큐프레독신 유래 펩타이드는 큐프레독신의 유도체이다. 상기 큐프레독신의 유도체는 펩타이드의 화학적 변형물이어서, 상기 펩타이드는 이의 기본적인 약학적 활성 중 일부를 여전히 보유한다. 예를 들어, 아주린의 "유도체"는 포유류의 암세포의 성장을 억제하는 능력을 보유하는 화학적으로 변형된 아주린일 수 있다. 관심이 있는 화학적 변형은 펩타이드의 탄화수소 안정화, 아미드화, 아세틸화, 황산화, 폴리에틸렌 글리콜(PEG) 변형, 인산화 및 글리코실화를 포함하지만, 이에 제한되지 않는다. 게다가, 펩타이드의 유도체는 큐프레독신과 화합물의 융합이거나, 큐프레독신의 변이체, 유도체 또는 구조적 등가물과 화합물의 융합일 수 있으며, 상기 화합물은 또 다른 펩타이드, 약물 분자 물질, 다른 치료제, 다른 약제 또는 검출가능한 프로브일 수 있으며, 이에 제한되지 않는다. 관심있는 유도체는 혈류 중의 본 발명의 펩타이드 및 조성물의 반감기가 당해 분야에서 잘 알려진 몇몇의 방법에 의해 연장되거나 최적화될 수 있는 화학적 변형을 포함하며, 상기 당해 분야에 잘 알려진 방법은 원형화된 펩타이드(예를 들어, Monk 등, BioDrugs 19(4):261-78, (2005); DeFreest 등, J. Pept. Res. 63(5):409-19 (2004) 참조), N- 및 C- 말단 변형(예를 들어, Labrie 등, Clin. Invest. Med. 13(5):275-8, (1990) 참조), 및 올레핀을 함유하는 비-천연 아미노산 이후에 탄화수소 봉합(예를 들어, Schafmeister 등, J. Am. Chem. Soc. 122:5891-5892 (2000); Walenski 등, Science 305:1466-1470 (2004) 참조)을 포함하지만, 이에 제한되지 않는다.
또 다른 실시예에서, 상기 펩타이드는 큐프레독신의 구조적 등가물 또는 큐프레독신의 절단이다. 큐프레독신 과 다른 단백질 간의 상당한 구조적 상동을 확인하는 연구의 예는 문헌[Toth 등, Development Cell 1:82-92 (2001)]을 포함한다. 구체적으로, 큐프레독신과 구조적 등가물 간의 상당한 구조적 상동은 VAST 알고리즘을 사용하여 확인된다(Gibrat 등, Curr Opin Struct Biol 6:377-385 (1996); Madej 등, Proteins 23:356-3690 (1995)). 구체적 실시예에서, 구조적 등가물에 대한 큐프레독신의 구조적 비교로부터 얻은 VAST p 값은 약 10-3 미만, 약 10-5 미만 또는 약 10-7 미만이다. 다른 실시예에서, 큐프레독신과 구조적 등가물 간의 상당한 구조적 상동은 DALI 알고리즘을 사용함으로써 확인된다(Holm & Sander, J. Mol. Biol. 233:123-138 (1993)). 구체적 실시예에서, 쌍별 구조적 비교에 대한 상기 DALI Z 점수는 적어도 약 3.5, 적어도 약 7.0 또는 적어도 약 10.0이다.
관심이 있는 하나의 특정 큐프레독신 유래 펩타이드는 큐프레독신의 진입 도메인과 카르고 화합물의 융합물이다. 일부 실시예에서, 큐프레독신 유래 펩타이드는 포유류의 암세포안으로 특이적으로 진입할 수 있고, 따라서 카르고 화합물을 세포 안, 구체적으로 암세포 안으로 전달하기 위해 사용될 수 있다. 큐프레독신 운반 펩타이드는 큐프레독신 진입 도메인을 포함한다. 상기 용어 "큐프레독신 진입 도메인"은 포유류의 암세포 안으로 큐프레독신의 진입에 필요한 아미노산 서열을 포함하는 큐프레독신의 절편을 나타낸다. 구체적 실시예에서, 상기 큐프레독신 운반 펩타이드는 서열번호:13 내지 서열번호:17이거나, 또 다른 큐프레독신으로부터 유래된 동등한 잔기이다. 본 발명은 약물 동력학 성질을 개선하도록 변형된 카르고 화합물과 함께 복합체를 형성하는 큐프레독신 운반 펩타이드를 아우른다. 상기 카르고 화합물뿐만 아니라 큐프레독신 운반 펩타이드는 약물 동력학 성질을 개선하기 위해서 본 명세서에 설명된 방법에 의해 변형될 수 있다. 이후에, 이러한 복합체는 암을 앓는 환자를 치료하기 위해 포유류의 암세포 안으로 카르고 화합물을 전달하는 본 발명의 방법에 사용될 수 있다. 물질에 의해 전달되는 카르고 화합물 및 본 발명의 방법은 단백질, 지질단백질, 폴리펩타이드, 펩타이드, 다당류, 안티센스 핵산을 포함하는 핵산, 염료, 형광 및 방사능 태그(tag), 극미립자 또는 나노미립자, 독소, 무기 및 유기 분자, 금속, 소분자 및 약물을 포함하지만, 이에 제한되지 않는다. 일부 실시예에서, 상기 약물 및 독소는 종양 세포를 죽인다. 이러한 큐프레독신 운반 펩타이드 및 이로 구성된 복합체는 2005년 10월 6일에 출원된 미국특허 출원번호 11/244,105에서 제공되고, 이는 전체가 참조로 본 명세서에 포함된다.
일부 실시예에서, 카르고 화합물 및 큐프레독신 유래 펩타이드 간의 융합은 세포 안으로 융합된 펩타이드가 진입한 후에 선택적으로 쪼개지는 연결에 의할 수 있다. 일부 실시예에서, 이러한 연결은 큐프레독신 운반 펩타이드-카르고 화합물 복합체의 약물 동력학 성질을 개선한다. 일부 실시예에서, 혈장 중의 큐프레독신 운반 펩타이드-카르고 화합물 복합체의 안정성은 향상된다. 일부 실시예에서, 상기 연결은 포유류 세포의 리소좀에서 선택적으로 쪼개진 것일 수 있다. 다른 실시예에서, 상기 연결은 카텝신 B에 의해 쪼개진 것일 수 있으며, 시스테인 단백질 분해효소는 리소좀 또는 암성 부위나 관절염 부위에 근접하여 세포 밖으로 위치했다. 일부 이러한 실시예에서, 상기 연결은 Val-Cit 연결이다.
또 다른 실시예에서, 펩타이드는 큐프레독신, 또는 큐프레독신의 변이체, 구조적 등가물, 또는 글루코오스-조절 단백질 78(GRP78)에 특이적으로 결합하여 암세포 안으로 내재화되는 Pep 42, 고리형 13-mer 올리고펩타이드, CTVALPGGYRVRVC(서열번호:3505)의 결합체인 큐프레독신의 유도체이다. 상기 큐프레독신 또는 변이체, 구조적 등가물, 또는 큐프레독신의 유도체는 문헌[Yoneda 등, "A cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy" Bioorganic & Medicinal Chemistry Letters 18: 1632-1636 (2008)]에서 개시되는 합성 방법에 따라서 Pep42(서열번호:3505)와 결합될 수 있으며, 상기 공개 문헌은 본 명세서에 전체로 포함된다.
일부 실시예에서, 상기 큐프레독신 유래 펩타이드는 Pep42(서열번호:3505)에 부착될 수 있다. 일부 실시예에서, Pep42(서열번호:3505)는 약물과 더 융합될 수 있다. Pep42(서열번호:3505)는 글루코오스 조절 단백질 78(GRP78)에 특이적으로 결합한다고 알려져 있으며, 상기 GRP78은 암세포에서 과다 발현되고, 암세포 표면상에 특히 존재한다(Yoneda, 등, Bioorganic & Medicinal Chemistry Letters 18 1632-1636 (2008)). Pep42(서열번호:3505)는 GRP78 수용체를 통해 효과적으로 국재화된다. 따라서, 일부 실시예에서 큐프레독신 유래 펩타이드-Pep42 융합 펩타이드는 암세포에 대하여 향상된 특수성을 가질 수 있다. 일부 이러한 실시예에서, Peo42(서열번호:3505) 및 큐프레독신 유래 단백질 간의 융합은 Val-Cit 연결, 카텝신 B를 통해 이루어질 수 있다. 일부 실시예에서, 상기 Pep42-약물 결합체는 Val-Cit 연결을 통해 이루어질 수 있다. 카텝신 B-쪼개질 수 있는 링커를 함유하는 Pep42-약물 결합체는 혈장에서 안정하고, 목표된 조직에 특이적으로 이들의 약물을 선택적으로 방출하는 경항이 있다. 본 발명의 일부 실시예에서, Pep42(서열번호:3505)는 아미드 결합을 통해 p-아미노벤질알콜에 연결되며, 이후에 카보네이트 또는 카바메이트 작용기를 통해 약물 또는 큐프레독신 유래 펩타이드에 부착된다. 이러한 실시예에서, 암세포 내에서 효소에 의한 쪼개짐은 변형되지 않은 큐프레독신 유래 단백질 또는 약물을 세포 안으로 전달한다.
일부 실시예에서, 상기 큐프레독신 유래 펩타이드는 치료적 응용, 진단 및 영상화에 사용할 수 있는 혼성 시스템(hybrid system)을 만들기 위해 나노입자, 예를 들어 금 또는 백금과 같은 귀금속과 결합된다.
일부 실시예에서, 소정의 약학적 활성을 갖는 큐프레독신들 중에서 보존되는 큐프레독신 유래 펩타이드의 아미노산 잔기는 개선된 약물 동력학 성질을 갖는 변형된 큐프레독신 유래 펩타이드로 보존된다. 예를 들어, 녹농균 아주린의 큐프레독신 진입 도메인 내에서, 몇몇의 잔기는 녹농균, 슈도모나스 시린게, 임균, 장염비브리오균 및 보데텔라 브론키셉티가와 같은 몇몇 종으로부터 유래된 아주린 및 아주린 유사 단백질 중에서 보존된다고 알려져 있다(Yamada 등, Cell. Microbiol. 7:1418- 1431 (2005)). 일부 실시예에서, 상기 큐프레독신 유래 펩타이드는 녹농균 아주린(서열번호:1)의 62번, 63번, 69번, 72번, 74번 및 77번 잔기에 대응되는 하나 이상의 아미노산 잔기를 보유한다. 또 다른 실시예에서, 큐프레독신 펩타이드는 보존된 아미노산 서열 DGXXXXXDXXYXKXXD(서열번호:46) 또는 DGXXXXDXXYXKXXD(서열번호:47)을 포함하며, 상기 D는 아스파르트산, G는 글리신, Y는 티로신, K는 리신 및 X는 임의의 아미노산이다.
변형
본 발명은 변이체 또는 유도체 또는 절단인 큐프레독신 유래 펩타이드의 변형물과 관련이 있고, 구체적 실시예로, 하나 이상의 약학적 활성을 유지하고/유지하거나 펩타이드의 약물 동력학 성질을 개선하는 큐프레독신 유래 펩타이드의 변형물에 관한 것이다. 이러한 변형은 펩타이드의 안정성, 특이적 활성, 혈장 반감기를 증가시킬 수 있고/있거나 큐프레독신 유래 펩타이드의 면역원성을 감소시킬 수 있는 반면에, 포유류 암세포에 진입하는 큐프레독신의 능력 및/또는 포유류 암세포의 성장을 억제하는 능력을 보유하는 펩타이드의 변이체 및 유도체를 포함하지만, 이제 제한되지 않는다. 이러한 변이체는 펩타이드의 가수분해를 감소시키며, 펩타이드의 탈아미드화를 감소시키며, 산화를 감소시키며, 면역원성을 감소시키고/감소시키거나 펩타이드의 구조적 안정성을 증가시키는 것을 포함하지만, 이에 제한되지 않는다. 본 명세서에서 설명되는 두 개 이상의 변형물은 하나의 변형된 큐프레독신 유래 펩타이드로 결합될 수 있을 뿐만 아니라, 약물 동력학 성질을 개선하기 위해서 본 명세서에서 설명된 하나 이상의 변형물들이 다른 변형물과 조합될 수 있고, 이러한 사실은 통상의 기술자에게 잘 알려져 있다. 이러한 변이체 및 유도체를 설계하기 위한 많은 방법은 당해 분야에 잘 알려져 있다.
큐프레독신 또는 시토크롬 c551, 또는 이들의 변이체, 유도체, 절단 또는 구조적 등가물을 화학적으로 변형하는 하나의 방법은 개선된 약학적 성질을 갖는 항-HIV 소 단백질, CCL-5(RANTES)를 설계하기 위해 이용하는 단계를 따를 수 있으며, 상기 개선된 약학적 성질은 예를 들어, 소수성 N-말단 변형, 총 단백질-폴리머 결합체 화학물질 합성, 암호화 및 비암호화된 아미노산 돌연변이, 펩타이드 골격 가공 및 위치-특이적 폴리머 부착에 의해 얻어진다. 항-HIV 단백질은 천연 및 비-천연 아미노산 잔기를 다양한 부착 위치에서 폴리머 치환기를 드러내는 CCL-5 유사체 안에 포함시킴으로써 설계될 수 있다. 시험관 안에서 폴리머-변형된 CCL-5 유도체의 항-HIV 활성은 CCR-5 신호와 연관성을 보여서, 펩타이드로의 변화는 CCR-5 활성을 교란하지 않을 것이다(Miranda, 등, J. Am. Chem. Soc. 129: 13153-13159 (2007) 참조). 상기 문헌은 전체가 본 명세서에 포함된다.
생체 내 변화
펩타이드의 약물 동력학 성질을 개선하기 위한 하나의 접근법은 생체 내 변화에 덜 영향받는 큐프레독신 유래 펩타이드의 변이체 및 유도체를 만드는 것이다. 생체 내 변화는 펩타이드의 약학적 활성을 감소시킬 뿐만 아니라 이것이 환자의 신체로부터 제거되는 속도를 증가시킨다. 이를 달성하기 위한 하나의 방법은 가장 생체 내 변화될 거 같은 아미노산 및/또는 아미노산 서열을 결정하고, 이러한 아미노산을 특정 생체 내 변화 과정에 덜 영향받는 아미노산으로 치환하여 확인하는 것이다.
일부 실시예에서, 상기 큐프레독신 유래 펩타이드는 비-천연 아미노산 또는 변형된 아미노산을 포함할 수 있다. 일부 실시예에서, 어떤 비-천연 아미노산의 도입은 큐프레독신 유래 펩타이드의 약물 동력학 성질을 향상시킨다. 이러한 도입은 위치 특이적일 수 있으며, 생체 내에서 어떤 생화학적 변형을 방지하기 위해 실행될 수 있다. 예시적인 비-천연 아미노산은 β-아미노산(예, b3 및 b2), 호모아미노산, 고리형 아미노산, 방향족 아미노산, Pro 및 Pyr 유도체, 3-치환된 알라닌 유도체, 글리신 유도체, 고리가 치환된 Phe 및 Tyr 유도체, α,α 이치환된 아미노산, 선형 중심 아미노산(Linear Core Amino Acid) 및 디아미노산(Diamino Acids)을 포함한다. 이러한 비-천연 아미노산은 부위 특이적 변형, 리보솜의 번역에 의해 펩타이드 안으로 포함될 수 있거나, 펩타이드의 화학적 합성에 의해 포함될 수 있다. 각각의 이러한 방법은 큐프레독신 유래 펩타이드 합성에 적용될 수 있다.
예를 들어, 변형된 큐프레독신 유래 펩타이드는 비-천연 큐프레독신 생산을 위한 비-천연 아미노산과 함께 야생형 아미노아실-tRNA 합성효소(AARSs)를 사용함으로써 합성될 수 있다(Hartman, 등, PLoS One, 2(10): e972 (2007); Miranda, 등, J. Am. Chem. Soc. 129: 13153-13159 (2007) 참조). 리보솜의 번역 장치의 특이성은 리보솜의 번역을 이용하여 펩타이드 안으로 포함될 수 있는 비-천연 아미노산의 다양성을 제한한다. AARS 기질인 90개가 넘는 비-천연 빌딩블록(building block)은 측쇄 및 골격 유사체를 포함하여 다루어지지 않는다(Hartman, 등, PLoS One, 2(10): e972 (2007)). 50개를 넘는 비-천연 아미노산은 모든 효소 번역 시스템을 사용하여 고 효율을 갖도록 펩타이드 안에 포함될 수 있으며, 상기 펩타이드는 최대 13개의 상이한 비-천연 아미노산을 함유한다(Hartman, 등, PLoS One, 2(10): e972 (2007)). 비-천연 아미노산은 4-플루오로-글루타메이트, 4-메틸 유사체, L-트레오-β 아스파르트산, S-2-아미노데틸 시스테인, trans-디히드로 리신, aza-루신, L-카나바닌, L-NG-메틸 아르기닌, NG히드록시 아르기닌, 비닐-L-NIO, DL-β-히드록시 노르발린, L-Glu y-메틸에스테르, L-Asp β-메틸에스테르,L-글루탐산 y-히드라자이드, L-알비진(albizziine), L-테아닌, β-2-티아졸일-알라닌, β-(1,2,4-트리아졸-3-일-알라닌), 3-플루오로티로신, 3-플루오로발린, 3-니트로티로신, 2-플루오로 Phe, 2-티에닐 Ala, β-메틸 Phe, β-티에닐 Ser, p-니트로페닐알라닌, 3-(티아나프텐-3-일)-L-알라닌, L-퀴스퀄산(quisqualic acid), 이보텐산, DL-α-(2-티에닐)글리신, L-페닐글리신, 2-아미노 헥스-5-이노산, 크로틸글리신, L-노르루신, L-노르발린, L-에티오닌, L-β-아지도호모알라닌(azidohomoalanine), 6,6,6-트리플루오로노르루신, 2-아미노-4,4,4-트리플루오로부티르산, L-C-프로파길글리신, L-알릴글리신, β-시클로프로필알라닌, 포토-Met, 3-플루오로-발린, ㅅ-부틸-글리신, O-메틸-L-트레오닌, (2S,3S)-2아미노-3-메톡시부탄산, 4-티아-이소루신, L-시클로헥실글리신, 5',5',5'-트리풀루오로루신, β-t-부틸-알라닌, β-시클로펜틸알라닌, 포토-Leu, 티아졸리딘-2-카복실산, 티아졸리딘-4-카복실산, 3,4,-디히드로프롤린, L-아제티딘-2-카복실산, 1-아미노시클로펜탄산, 1-아미노시클로헥산산, β-히드록시산, N-메틸 His, N-메틸 Asp, α-히드록시산, 및 α-히드록시메티오닌을 포함하지만, 이에 제한되지 않는다. Hartmann과 Miranda의 참조문헌 및 이러한 참조 문헌에서 설명되고 개시되는 모든 비-천연 빌딩블록 및 아미노산은 본 명세서에 전체가 참조로서 포함된다. 일부 실시예에서, 이러한 아미노산은 큐프레독신 유래 펩타이드에 포함될 수 있다. 다른 변형은 광학적으로 활성인 α-아미노산의 사용을 포함할 수 있다. 광학적으로 활성인 α-아미노산 및 이의 유도체의 사용은 약,농약 및 카이랄(chiral) 리간드로서 이들을 사용하기 위해 확장된다. 특히, 카이랄 글리신 및 알라닌 등가물은 중요한 역할을 계획한다. α-아미노산을 고안하기 위한 적어도 하나의 입체선택적 계획이 제안되었으며, 이는 기결정된 입체 화학에서 순수한 거울쌍 이성질체 α-아미노산을 갖게 한다(Lu, 등, "Asymmetric Synthesis of α-amino acids: Preparation and alkylation of monocyclic iminolactones derived from α-Methyl trans-cinnamaldehyde" 2008년 9월 11일에 인터넷에 개재됨 (J. Org. Chem.에 게재됨)). 변형된 큐프레독신 유래 펩타이드는 광학이성질체적으로 강화된 반복을 초래하도록 광학적으로 활성인 α-아미노산을 사용하여 합성될 수 있다.
가수분해는 아스파르테이트(aspartate)를 함유하는 펩타이드의 일반적인 문제점이다. 아스파르테이트는 고리형 이미드 중간체를 형성하기 위한 탈수반응에 영향을 받아, 아스파르테이트를 잠재적으로 비활성인 이소-아스파르테이트 유사체로의 전환을 유발하고, 궁극적으로 펩타이드 쇄를 쪼갠다. 예를 들어, 펩타이드 서열 중의 아스파트르산-프롤린의 존재하에서, 고리형 이미드 중간체의 산 촉매화된 형태는 펩타이드 쇄의 쪼개짐을 야기할 수 있다. 이와 유사하게, 펩타이드 서열 중의 아스파르트산-글리신의 존재하에서, 고리형 중간체는 초기의 아스파르테이트 형태(해롭지 않음)로 가수 분해되거나 이소-아스파르테이트 유사체로 가수분해 될 수 있다. 결국, 모든 아스파르테이트 형태는 이소-아스파르테이트 유사체로 완전히 전화될 수 있다. 또한, 세린을 갖는 유사한 서열은 펩타이드 쇄로 쪼개질 수 있는 고리형 이미드 유사체를 형성하기 위해 탈수될 수 있다. 펩타이드의 쪼개짐은 혈장 반감기의 감소를 야기할 뿐만 아니라 펩타이드의 특이적 약학적 활성의 감소를 야기할 수 있다. 큐프레독신 유래 펩타이드의 서열 중 아스파라긴 및/또는 세린에 대하여 다른 아미노산으로 치환하는 것은 더 길어진 혈장 반감기 및 펩타이드의 약학적 활성의 증가된 특이적 활성과 같은 개선된 약물 동력학 성질을 갖는 펩타이드를 야기할 수 있다고 생각된다. 예상되는 하나의 변이체에서, 큐프레독신 유래 펩타이드 중의 하나 이상의 아스파라긴 잔기는 다른 아미노산 잔기, 구체적으로 글루탐산 잔기로 치환될 수 있다. 다른 예상되는 변이체에서, 큐프레독신 유래 펩타이드 중 하나 이상의 세린 잔기는 또 다른 아미노산 잔기, 구체적으로 트레오닌 잔기로 치환될 수 있다. 큐프레독신 유래 펩타이드의 일부 변이체에서, 하나 이상의 아스파라긴 잔기 및 하나 이상의 세린 잔기는 치환된다. 일부 실시예에서, 보존적 치환이 이루어진다. 다른 실시예에서, 비보존적 치환이 이루어진다.
아미노산 잔기의 탈아미노화는 생체 내 변화에서 특히 문제점을 가진다. 염기 촉매화 반응은 아스파라긴-글리신 또는 글루타민-글리신을 함유하는 서열에서 종종 발생하고, 상기 아스파르트산-글리신 서열과 유사한 메커니즘이 진행된다. 아스파라긴--글리신 서열의 탈아미노화는 아스파르테이트 또는 아스파라긴의 이소-아스파르테이트 유사체를 형성하기 위해 차후에 탈수되는 고리형 이미드 중간체를 형성한다. 게다가, 상기 고리형 이미드 중간체는 D-아스파르트산 또는 아스파라진의 D-이소-아스파르트산 유사체로의 라세미화를 야기할 수 있으며, 이들 모두는 펩타이드의 비활성 형태를 강력히 야기할 수 있다.
큐프레독신 펩타이드의 탈아미노화는 글리신, 아스파라긴 및/또는 큐프레독신의 아스파라긴-글리신 또는 글루타민-글리신 잔기의 글루타민을 또 다른 아미노산으로 치환함으로써 보호할 수 있고, 더 길어진 혈장 반감기 및 펩타이드의 약학적 활성의 증가된 특이적 활성과 같은 개선된 약물 동력학 성질을 갖는 펩타이드를 야기할 수 있다. 일부 실시예에서, 큐프레독신 유래 펩타이드 중 하나 이상의 글리신 잔기는 또 다른 아미노산 잔기에 의해 치환된다. 구체적 실시예에서, 상기 큐프레독신 유래 펩타이드 중 하나 이상의 글리신은 트레오닌 또는 알라닌 잔기에 의해 치환된다. 일부 실시예에서, 상기 큐프레독신 유래 펩타이드 중 하나 이상의 아스파라긴 또는 글루타민은 또 다른 아미노산 잔기에 의해 치환된다. 구체적 실시예에서, 상기 큐프레독신 유래 펩타이드 중 하나 이상의 아스파라긴 또는 글루타민은 알라닌 잔기에 의해 치환된다. 다른 구체적인 실시예에서, 녹농균 아주린(서열번호:1)의 58번 및/또는 63번 잔기에 있는 글리신 또는 다른 큐프레독신 중 동등한 글리신은 알라닌 또는 트레오닌으로 치환된다. 다른 구체적인 실시예에서, 녹농균 아주린(서열번호:1)의 59번 잔기에 있는 메티오닌 또는 또 다른 큐프레독신 유래 펩타이드 중 동등한 메티오닌 잔기는 알라닌 잔기에 의해 치환된다. 다른 구체적인 실시예에서, 녹농균 아주린(서열번호:1)의 63번 잔기에 있는 글리신 또는 또 다른 큐프레독신 유래 펩타이드 중 동등한 글리신 잔기는 트레오닌 잔기에 의해 치환된다. 일부 실시예에서, 보존적 치환이 이루어졌다. 다른 실시예에서, 비보존적 치환이 이루어졌다. 구체적인 실시예에서, 본 발명의 변형된 큐프레독신 유래 펩타이드는 다음의 서열을 포함하며, 이 때 밑줄그은 아미노산은 야생형 녹농균 아주린 서열로 치환된다:
LSTAADMQAVVTDTMASGLDKDYLKPDD(서열번호:30).
아미노산의 가역적 및 비가역적 산화는 약학적 활성 및/또는 큐프레독신 유래 펩타이드의 혈장 반감기를 감소시킬 수 있는 문제점을 제기할 수도 있는 다른 생체 내 변화 과정이다. 시스테인 및 메티오닌 잔기는 가역적 산화를 겪는 유력한 잔기이다. 시스테인의 산화는 높은 pH에서 가속화되며, 이러한 높은 pH에서 티올은 더 쉽게 탈양성자화 되어 손쉽게 쇄내(intra-chain) 또는 쇄내 이황화 결합을 형성한다. 이러한 이황화 결합은 디티오트레이톨(DTT) 또는 tris(2-카복시에틸포스핀)히드로클로라이드(TCEP)로 처리하여 시험관 안에서 손쉽게 역(reversed)될 수 있다. 메티오닌은 메티오닌 설폭시화물(sulfoxide)을 형성하고 나아가 메티오닌 설폰을 형성하기 위해 화학적 및 광화학적 경로 모두를 통해 산화되며, 메티오닌 설폭시화물 및 메티오닌 설폰 모두 역되는 것이 거의 불가능하다. 큐프레독신 유래 펩타이드의 산화는 메티오닌 및/또는 시스테인 잔기를 다른 잔기로 치환함으로써 보호할 수 있다고 생각된다. 일부 실시예에서, 큐프레독신 유래 펩타이드의 하나 이상의 메티오닌 및/또는 시스테인 잔기는 또 다른 아미노산 잔기에 의해 치환된다. 구체적인 실시예에서, 상기 메티오닌 잔기는 루신 또는 발린 잔기로 치환된다. 다른 구체적인 실시예에서, 녹농균 아주린(서열번호:1)의 56번 및 64번 잔기에 있는 하나 이상의 메티오닌, 또는 다른 큐프레독신 유래 펩타이드의 동등한 메티오닌 잔기는 루신 또는 발린으로 치환된다. 일부 실시예에서, 보존적 치환이 이루어진다. 다른 실시예에서, 비-보존적 치환이 이루어진다. 구체적인 실시예에서, 본 발명의 큐프레독신 펩타이드는 하나 이상의 다음 서열을 포함하며, 이 때 밑줄그은 아미노산은 야생형 녹농균 아주린 서열로 치환된다:
LSTAADLQGVVTDGLASGLDKDYLKPDD(서열번호:31) 또는
LSTAADVQGVVTDGVASGLDKDYLKPDD(서열번호:32).
큐프레독신 유래 펩타이드의 약학적 활성, 혈장 반감기 및/또는 면역원성에 영향을 미치는 또 다른 생체 내 변화 과정은 디케토피페라진 및 피로글루탐산 형성이다. 디케토피페라진 형성은 글리신이 N-말단으로부터 3번째 위치에 있는 경우에 보통 발생하고, 더 특히 만일 프롤린 또는 글리신이 1번 또는 2번 위치에 있는 경우에 발생한다. 상기 반응은 2번 및 3번 아미노산 사이의 아미드 카보닐 상의 N-말단 질소가 친핵체 공격을 받는 것을 수반하며, 이는 디케토피페라진의 형태에서 최초 두 개의 아미노산의 쪼개짐을 야기한다. 반면에, 피로글루탐산 형성은 안약 글루타민이 N-말단에 있으면 거의 필연적일 수 있다. 이는 N-말단 질소가 글루타민의 측쇄 카보닐 탄소를 공격하여 탈아미노화된 피로글루타마일(pyroglutamayl) 펩타이드 유사체를 형성하는 것과 유사한 반응이다. 또한, 이런 개조는 N-말단에 아스파라진을 함유하는 펩타이드에서 발생하지만, 발생 정도는 매우 적은 정도이다.
펩타이드의 N-말단으로부터 1, 2 또는 3번째 위치에 있는 글리신, N-말단으로부터 3번째 위치에 있는 프롤린 또는 N-말단에 있는 아스파라긴을 또 다른 아미노산 잔기로 치환함으로써, 디케토피페라진 및 피로글루탐산 형성은 큐프레독신 유래 펩타이드에서 줄어들 수 있다. 일부 실시예에서, 큐프레독신 유래 펩타이드의 N-말단으로부터 1, 2 또는 3번째 위치에 있는 글리신은 또 다른 아미노산 잔기로 치환될 수 있다. 구체적 실시예에서, 상기 글리신 잔기는 트레오닌 또는 알라닌 잔기에 의해 치환된다. 또 다른 실시예에서, 큐프레독신 유래 펩타이드의 N-말단으로부터 3번 위치에 있는 프롤린은 또 다른 아미노산 잔기로 치환된다. 구체적인 실시예에서, 상기 프롤린은 알라닌 잔기에 의해 치환된다. 또 다른 실시예에서, N-말단에 있는 아스파라긴은 또 다른 아미노산 잔기로 치환된다. 구체적인 실시예에서, 상기 아스파라긴 잔기는 글루타민 잔기에 의해 치환된다. 일부 실시예에서, 보존적 치환이 이루어진다. 다른 실시예에서, 비-보존적 치환이 이루어진다.
큐프레독신 유래 펩타이드의 약학적 활성, 혈장 반감기 및/또는 면역원성에 영향을 미치는 또 다른 생체 내 변화 과정은 라세미화이다. 이 용어는 아미노산 또는 펩타이드의 완전한 카이랄 상태를 전체적으로 잃는 것을 막연하게 나타내는데 사용된다. 라세미화는 아미노산 중 하나의 거울쌍 이성질체(보통 L-형)를 염기-촉매화를 통해 1:1의 L- 및 D-거울쌍 이성질체 혼합물로 전환하는 것을 수반한다. 보통, 펩타이드의 안정성을 개선하기 위한 하나의 방법은 역순 광학(retro inverso)(D-이성질체) 펩타이드를 만드는 것이다. 펩타이드 구조의 이중 반전은 종종 측쇄의 표면 위상 기하학을 온전하게 두며, 생물학적으로 활성인 펩타이드를 안정화시키기 위해 널리 사용되어 왔다(Snyder 등, PLoS Biol. 2:0186-0193 (2004)). Tat 치환된 D-아미노산은 세포 안으로 내재화될 뿐만 아니라 L-아미노산 또한 세포 안으로 내재화된다(Futaki 등, J. Biol. Chem. 276:5836-5840 (2001); Huq 등, Biochemistry 38:5172-5177 (1999)). 일부 실시예에서, 큐프레독신 유래 펩타이드 중 하나 이상의 아미노산 잔기는 아미노산 잔기의 D-이성질체에 의해 치환된다. 다른 실시예에서, 큐프레독신 유래 펩타이드 중 모든 아미노산 잔기는 이러한 잔기의 D-이성질체로 치환된다. 일 실시예에서, 변형된 큐프레독신 유래 펩타이드는 상기 큐프레독신 유래 펩타이드의 역순 광학(D-이성질체) 형태이다. 구체적 실시예에서, 상기 변형된 큐프레독신 유래 펩타이드는
DDPKLYDKDLGSAMGDTVVGQMDAATSL(서열번호:45)이다.
다른 구체적인 실시예에서, 상기 변형된 큐프레독신 유래 펩타이드는 서열번호:1777 내지 서열번호:3504를 포함하는 큐프레독신 유래 펩타이드의 역순 광학 형태이다.
생체 내 변화 저하로부터 큐프레독신 유래 펩타이드를 보호하는 다른 방법은 N-아세틸화 및 C-아미드화이다. 이러한 유도체는 저하로부터 펩타이드를 보호할 수 있고, 상기 큐프레독신 유래 펩타이드가 자생 단백질의 알파 아미노기 및 카복실기의 전하 상태를 더 면밀히 의태(mimic)하도록 만들 수 있다. N-아세틸화 및/또는 C-아미드화된 펩타이드는 상업적 공급자에 의해 제공될 수 있다. 본 발명의 일 실시예에서, 상기 큐프레독신 유래 펩타이드의 N-말단은 아세틸화될 수 있다. 본 발명의 또 다른 실시예에서, 큐프레독신 유래 펩타이드의 C-말단은 아미드화될 수 있다. 구체적인 일 실시예에서, 상기 변형된 큐프레독신 펩타이드는 아세틸화-LSTAADMQGVVTDGMASGLDKDYLKPDD-아미드화(서열번호:33)이다.
고리화는 본 명세서에서 설명되는 큐프레독신을 포함하는 치료용 펩타이드에 이로울 수 있는 생체 내 변화의 부가적인 방식이다. 고리화는 치료용 펩타이드를 안정화 시킬 수 있어서, 더 오래 저장될 수 있도록 하며, 낮은 투여량으로 투여되고 적은 빈도수로 투여될 수 있도록 한다. 고리화는 펩타이드 분해 효소 및 단백질 분해효소에 의한 저하에 대하여 펩타이드를 보호한다고 밝혀졌다. 고리화는 화학적으로 또는 효소에 의해 이루어질 수 있다. 효소에 의한 고리화는 일반적으로 화학적 고리화보다 적은 문제가 있으며, 화학적 고리화는 위치선택성 및 입체선택성이 부족할 수 있기 때문에, 고리화 대신에 다중화를 야기할 수 있고 복잡한 다단계 과정이 요구될 수 있다. 사실, 티오에테르 고리화가 단백질 가수분해 효소에 대하여 이황화 결합보다 더 보호하고 안정화한다고 밝혀졌다.
효소에 의한 고리화는 란티바이오틱(lantibiotic)-(메틸)란티오닌-함유 세균성 펩타이드에서 밝혀졌다. 예를 들어, 문헌[R. Rink, 등, "Lantibiotic Structures as Guidelines for the Design of Peptides That Can Be Modified by Lantibioitic Enzymes" 44 Biochem., 8873-82 (2005)]; 문헌[R. Rink, 등, "Production of Dehydroamino Acid-Containing Peptides by Lactococcus lactis" 73:6 Applied and Environmental Microbiology, 1792-96 (2007)]; 문헌[R. Rink, 등, "NisC, the Cylcase of the Lantibiotic Nisin, Can Catalyze Cyclization of Designed Nonlantibiotic Peptides" 46 Biochem., 13179-89 (2007)]이 있다(문헌 각각은 전체가 참조로 포함된다). 란티바이오틱은 그람양성균에 의해 생산될 수 있고, 그람 양성균의 성장을 억제한다. 란티바이오틱에서, 디히드로알라닌 및 디히드로부티린은 세린과 트레오닌 잔기의 효소 매개 탈수화에 의해 만들어진다. 이후에, 시스테인은 탈수된 세린 및 트레오닌 잔기에 효소에 의해 결합되어 티오에테르 고리화물을 형성한다. 자연적으로 발생하는 란티바이오틱은 최대 19개의 잔기 만큼 떨어져 있는 잔기들 사이에서 티오에테르 결합을 통해 결합하는 것을 보여준다. 티오에테르 고리 형성은 선도 펩타이드에 의해 결정된다. 고리화의 위치는 고리화 효소 매개된 위치선택적 및 입체선택적 고리 닫힘 및 탈수가능한 세린과 트레오닌 잔기의 위치에 의해 결정된다.
란티바이오틱의 가장 큰 특징은 락토코쿠스 락티스(Lactococcus lactis)에 의해 생산되는 오각고리 펩타이드 항생제인 니신(nisin)이다. 니신은 4개의 메틸란티오닌, 하나의 란티오닌, 두 개의 디히드로알라닌, 하나의 디히드로부티린 및 26개의 변형되지 않은 아미노산으로 구성된다. 니신의 5개의 티오에테르 가교는 시스테인 잔기를 세린 및 트레오닌으로부터 유래되는 디히드로알라닌 및 디히드로부티린 잔기에 첨가함으로써 형성된다. 니신은 번역후에 막-연관 효소 복합체에 의해 도입되는 티오에테르-함유 아미노산을 함유한다. 이 효소 복합체는 운반체 NisT, 세린 및 트레오닌 탈수 효소 NisB 및 고리화 효소 NisC를 포함한다. NisB는 세린 및 트레오닌 잔기를 탈수하여, 이들을 디히드로알라닌 및 디히드로부티린으로 각각 전환시킨다. 이어서 NisC는 형성된 탈수 잔기에 대한 시스테인의 거울상 선택적 결합을 촉진시겼다. NisT는 변형된 프레니신의 전파를 가능하게 한다. 또 다른 효소, NisP는 프레니신으로부터 니신 선도펩타이드를 쪼갠다.
고리화 효소 NisC는 잘 특징지어졌다. 문헌[Li 등, "Structure and Mechanism of the Lantibiotic Cylclase Involved in Nisin Biosynthesis" 311 Science, 1464-67 (2006)], 전체가 참조로 본 명세서에 포함된다.
란티바이오틱에서 고리화의 분석은 아미노산 서열 및 고리화를 가능케 하는 펩타이드의 특징을 식별하게 했다. NisB 효소는 어떤 아미노산이 세린 및 트레오닌 잔기의 측면을 우회하는 곳에서 더 자주 탈수를 시킨다고 밝혀졌다. 고리화는 소수성, 비방향성 잔기가 세린 및 트레오닌 잔기에 근접하는 란티바이오틱 프로펩타이드(propeptide)에서 더 자주 발생한다고 밝혀졌다. 변형된 시스테인의 측면 잔기는 변형된 트레오닌과 세린의 측면 잔기보다 보통 덜 소수성이다. 예외를 발견했으며, 상기 예외는 헥사펩타이드 VSPPAR(서열번호:3528), YTPPAL(서열번호:3529) 및 FSFFAF(서열번호:3530)을 포함한다. 상기 헥사펩타이드는 3번 또는 4번 위치에 프롤린이 존재하거나 양쪽 측면에 페닐알라닌을 갖는 것이 탈수를 금지시킬 수 있다는 것을 시사한다. 고리는 탈수된 잔기를 C-말단에 위치된 시스테인에 결합시킴으로써 일반적으로 형성된다. 반면에, 고리는 탈수된 잔기를 N-말단에 위치된 시스테인에 결합시킴으로써 형성될 수 있다.
또한, 니신 탈수 및 운반 효소는 니신에 특이적이지 않고, 비-니신 펩타이드(및 비-란티바이오틱 펩타이드)를 변형하기 위해 사용될 수 있다. NisB는 이런 펩타이드가 N-말단에서 란티바이오틱 선도 펩타이드에 융합되는 경우에 인간 펩타이드와 같은 펩타이드 중의 세린 및 트레오닌 잔기를 탈수시키는 것으로 밝혀졌다. 비-란티바이오틱 펩타이드에 관하여, 유사한 고리 형성 형질을 적용하며; 즉, 탈수의 정도는 탈수가능한 세린 및 트레오닌 잔기의 측면 영역의 아미노산 전후 관계에 의해 조절될 수 있다. 세린 및 트레오닌 주변으로 소수성 측면 잔기(예, 알라닌 및 발린)의 존재는 완전한 탈수를 가능하게 하여서 티오에테르 고리 형성을 향상시켰다. N-말단 아스파르테이트 및 C-말단 측면에 배치된 아르기닌의 존재는 탈수를 막았다. 또한, 프롤린 잔기 및 페닐알라닌 잔기의 존재는 탈수에 부적합하다는 것을 보여줬다. 일반적으로, 친수성 측면 잔기의 존재는 세린 및 트레오닌 잔기의 탈수를 막았다. 소수성 측면 잔기는 탈수에 유리하며; 친수성 측면 잔기는 탈수에 불리하다.
연구는 탈수가 일어나는 곳에서 세린 및 트레오닌의 측면 잔기의 평균 소수성은 N-말단 상에서 0.40 그리고 C-말단 상에서 0.13이다. 또한, 탈수되지 않은 세린 및 트레오닌의 측면 잔기의 평균 소수성은 N-말단 상에서 -0.36 그리고 C-말단 상에서 -1.03이다. 탈수는 일련의 측면 트레오닌의 존재에 의해 제한되지 않고, 니신 선도 펩타이드와 탈수될 잔기 간의 거리에 의해 제한되지 않는다.
NisC는 자연적으로 발생되는 란티바이오틱에 관련되지 않는 펩타이드 중의 티오에테르 고리의 위치선택적 형성을 촉진한다고 밝혀졌다. 일반적으로, 이러한 펩타이드는 니신 선도 펩타이드에 융합되어야 한다. 일부 경우에서, 티오에테르 고리는 예를 들어, 디히드로알라닌이 시스테인으로부터 2개의 아미노산만큼 떨어져 있는 곳에서 자발적으로 형성될 수 있다. 자발적 고리화와 다르게, NisC 촉진된 고리화는 탈수된 프리-니신(pre-nisin)에 대하여 입체 특이적이다. 따라서, 니신 중의 메틸란티오닌 및 란티오닌은 DL 배열이다. 비-란티바이오틱 펩타이드에서 고리화도 입체 특이적일 것이라고 생각된다. 이러한 원리는 큐프레독신 및 이들의 변이체와 절단을 포함하는 본 명세서에서 설명된 화합물에 적용될 수 있다.
티오에테르 브릿지
사실상, 란티바이오틱-효소-유도 티오에테르 브릿지는 브릿지 안에 최대 19개의 아미노산으로 발생된다. 브릿지안에 2 내지 4개의 아미노산을 갖는 티오에테르 브릿지는 풍부하다. 일부 실시예에서, 큐프레독신은 티오에테르 브릿지를 구조에 도입함으로써 변형될 수 있다. 예를 들어, 아주린 절단 p28(서열번호:13)은 이 방법을 사용하여 변형될 수 있다. 소프트웨어 패키지 GROMAC(www.gromacs.org)를 사용하는 연장된 분자 동력학 시뮬레이션(70 ns)은 37 ℃에서 p28(서열번호:13) 알파 나선 6번 위치부터 16번 위치까지의 영역이 불안정하고 펩타이드가 베타 병풍구조 를 취하려고 한다는 것을 시사한다(도 4 참조). p53과 상호작용의 원인으로 추정되는 분자의 일부분이 용매에 노출된 상태로 남아 있다는 사실과 함께, p28(서열번호:13) 펩타이드의 영역에 티오에테르 브릿지의 도입은 이의 기능성에 영향을 주지 않을 수 있다는 것을 시사한다.
p28의 아미노산 서열은 서열번호:13(LSTAADMQGVVTDGMASGLDKDYLKPDD)이다. p18로 알려진 아미노산 서열은 서열번호:14(LSTAADMQGVVTDGMASG)이다. p28(서열번호:13) 내에서, 서열 SGLDKD( 서열번호:3531 )은 p53과 상호작용할 수 있다. 티오에테르 브릿지는 N-측 상의 Ser/Thr와 C-측 상의 Cys 간에 형성될 수 있다. 상기 세린/트레오닌은 탈수될 수 있고, 이후에 시스테인에 결합된다. 트레오닌이 세린보다 더 쉽게 탈수될 수 있기 때문에 트레오닌이 선호된다. 일반적으로, 트레오닌에 대한 소수성 측면 잔기(적어도 하나)가 탈수의 정도를 향상시키기 때문에 선호된다. 측면 잔기인 음전하로 하전된 아미노산, 글루타메이트 및 아스파르테이트는 탈수에 대하여 강한 악영향을 끼친다. 일반적으로, 친수성 측면 잔기, 특히 글리신은 탈수에 유리하지 않다. Cys에 앞서서 하전된 친수성 잔기, 특히 글루타메이트/아스파르테이트를 약간 선호한다. 티오에테르 고리의 크기, 고리 물질에 관련되는 아미노산의 큰 크기에 의존한다.
일 실시예에서, 절단된 아주린 서열은 서열번호:3507, LSTAADMQGVVTDGMASGLDKDYLTPGC이다. 티오에테르 브릿지는 25번 위치와 28번 위치 사이에서 형성되고, 카복시에티아아제(carboxyetidase)에 대하여 완전히 보호될 것이다. 2번, 3번 및 25번 위치는 탈수될 것이지만, 중요한 서열뿐만 아니라 p53과의 상호작용과 관련 있다고 생각되는 서열은 티오 에테르 고리를 도입함으로써 변형된다. 따라서, 펩타이드 활성은 바뀌지 않을 것이다. 트레오닌은 두 개의 소수성 아미노산 사이에 있어서, 구체적인 가이드라인에 따라 탈수 효소 NisB에 의해 완전히 탈수될 것으로 예상된다(Rink 등, Biochemistry 2005 참조). 또한, 동일한 가이드라인은 고리화 효소 NisC에 의하여 25번 위치와 28번 위치에서 수반되는 고리화를 예측하며, 특히 시스테인 이전에 위치된 아스파르테이트 때문에 그러하다.
또 다른 실시예에서, 절단된 아주린 서열은 LSTAADCQGVVTDGMASGLDKDYLKPDD, (서열번호:3508)이고 티오에테르 브릿지는 3번 위치와 7번 위치 사이에서 형성된다. 3번 위치와 7번 위치 간의 고리는 니신의 고리 A 처럼 보이고, 2번 위치에 존재하는 트레오닌을 이용한다. 6번 위치의 아스파르테이트는 고리화에 유리하다.
또 다른 실시예에서, 절단된 아주린 서열은 LSTAACMQGVVTDGMASGLDKDYLKPDD, (서열번호:3509)이고 2번 위치의 트레오닌은 티오에테르 브릿지를 형성하기 위해 활용된다.
또 다른 실시예에서, 상기 문단에서 설면되는 절단된 아주린 중의 두개 이상의 티오에테르 고리는 하나의 펩타이드로 결합된다.
또 다른 실시예에서, 많은 절단된 아주린 서열이 만들어질 수 있고, 황 브릿지 안에 하나의 란티오닌 및 두 개 내지 세 개의 추가 아미노산의 고리를 갖는 펩타이드를 분석함으로써 트레오닌 고리를 확인할 수 있다. 예를 들면, 이는 볼드체로된 돌연변이가 완전한 변형을 가능하게 하는 하기 서열 중 하나 이상의 조합을 포함할 수도 있다.
LSTACDMQGVVTDGMASGLDKDYLKPDD (서열번호:3510)
LSTAATMQCVVTDGMASGLDKDYLKPDD (서열번호:3511)
LSTAATMQGCVTDGMASGLDKDYLKPDD (서열번호:3512)
LSTAANTQGCVTDGMASGLDKDYLKPDD (서열번호:3513)
LSTAANTQGVCTDGMASGLDKDYLKPDD (서열번호:3514)
LSTAADMTAVCTDGMASGLDKDYLKPDD (서열번호:3515)
LSTAADMTAVVCDGMASGLDKDYLKPDD (서열번호:3516)
LSTAADMQTVVCDGMASGLDKDYLKPDD (서열번호:3517)
LSTAADMQTVVTCGMASGLDKDYLKPDD (서열번호:3518)
LSTAADMQATVTCGMASGLDKDYLKPDD (서열번호:3519)
LSTAADMQATVTDCMASGLDKDYLKPDD (서열번호:3520)
LSTAADMQGVTADCMASGLDKDYLKPDD (서열번호:3521)
LSTAADMQGVTADGCASGLDKDYLKPDD (서열번호:3522)
LSTAADMQGVVTNGCASGLDKDYLKPDD (서열번호:3523)
실현 가능한 접근법은 유전적으로 수많은 이러한 서열들을 만들고 변형의 정도 및 생산 수준에 기초하여 정제를 위한 군을 선택하는 것이다. 또 다른 실시예에서, 티오에테르 브릿지는 p28 중의 12번 위치에서 트레오닌과 펩타이드의 C-말단 사이에 형성된다. 13번 위치의 Cα와 28번 위치의 아스파르테이트 간의 거리는 17.52 옹스트롬(Å)이며, 1.5 nm를 초과할 수 있으며, 이는 펩타이드 구조의 현저한 변화를 의미한다(도 5 참조).
또 다른 실시예에서, 상기 펩타이드 서열은 4.38 Å 떨어져 있는 14번 위치와 2번 위치 사이에 티오에테르 브릿지를 갖는 LSTAADMQGVVTATMGSGLCKDYLKPDD, (서열번호:3524)이다. 13번 위치에서 있는 아스파르테이트가 알라닌으로 돌연변이 한 것은 14번 위치에 있는 트레오닌의 탈수에 유리하다. 16번 위치에 있는 알라닌이 글리신으로 돌연변이 한 것은 17번 위치에 있는 세린의 탈수를 완전히 막고 고리화를 향상시킨다.
또 다른 실시예에서, 펩타이스 서열은 5.38 Å 떨어져 있는 15번 위치와 20번 위치 사이에 티오에테르 브릿지를 갖는 LSTAADMQGVVTDLTASGLCKDYLKPDD, (서열번호:3525)이다. 이 경우에, 14번 위치에 있는 글리신이 루신으로 돌연변이 한 것은 15번 위치에 있는 트레오닌의 탈수에 유리하다.
3차 구조 안정화
큐프레독신 유래 펩타이드의 3차 구조의 안정화는 약학적 활성, 혈장 반감기 및/또는 면역원성을 포함하여, 약물 동력학의 모든 양태에 영향을 줄 것이다(Kanovsky 등, Cancer Chemother. Pharmacol. 52:202-208 (2003); Kanovsky 등, PNAS 23:12438-12443 (2001) 참조). 펩타이드 나선은 종종 불규칙 나사선으로 허물어져서, 단백질 분해 효소의 공격에 더 영향을 받게 되고, 세포막에 잘 침투할 수 없게 된다(Schafmeister 등, J. Am. Chem. Soc. 122:5891-5892 (2000)). 그러므로, 펩타이드의 전체 구조를 안정화하기 위한 한가지 방법은 펩타이드 α-나선 구조를 안정화 하는 것이다. 나선형과 연관된 분자 내 수소 결합은 극성 아미드 골격의 노출을 감소시킴으로써, 운반 펩타이드에서 막 침투에 대한 장벽을 감소시키고, 따라서 관련된 약학적 활성을 증가시키고 단백질 분해효소에 의한 펩타이드의 쪼개짐에 대한 저항성을 증가시킨다. Id. 녹농균 아주린(서열번호:1)은 53번 내지 56번, 58번 내지 64번 및 68번 내지 70번 잔기에서 α-나선을 가진다. α-나선을 안정화하기 위한 하나의 방법은 α-나선에서 글리신, 프롤린, 세린 및 아스파르트산과 같은 파괴 아미노산, 또는 알라닌, 트레오닌, 발린, 글루타민, 아스파라긴, 시스테인, 히스티딘, 리신 또는 아르기닌과 같은 나선 중성 아미노산을 루신, 이소루신, 페닐알라닌, 글루탐산, 티로신, 트립토판 및 메티오신과 같은 나선 형성 잔기, 또는 나선에 유리한 아미노산 잔기 치환, 예를 들어 α-아미노-이소부티르산(Aib)로 치환하는 것이다(Miranda 등, J. Med. Chem., 51, 2758- 2765 (2008) 참조). 큐프레독신 유래 펩타이드의 α-나선은 하나 이상의 글리신, 프롤린, 세린 및/또는 아스파르트산 잔기를 다른 아미노산으로 치환함으로써 안정화될 수 있다고 생각된다. 구체적인 실시예에서, 글리신, 프롤린, 세린, 아스파르트산, 알라닌, 트레오닌, 발린, 글루타민, 아스파라긴, 시스테인, 히스티딘, 리신 및/또는 아르기닌 잔기는 루신, 이소루신, 페닐알라닌, 글루탐산, 티로신, 트립토판, Aib 및/또는 메티오닌 잔기에 의해 치환된다(Lee 등, Cancer Cell Intl. 11 :21 (2005) 참조). 다른 구체적인 실시예에서, 큐프레독신 유래 펩타이드의 α-나선에서 하나 이상의 세린 또는 글루타민 잔기는 치환될 수 있다. 더 구체적인 실시예에서, 녹농균 아주린(서열번호:1)의 53번 내지 56번, 58번 내지 64번 및 68번 내지 70번 잔기에서 세린 및/또는 글루타민 잔기, 또는 다른 큐프레독신 유래 펩타이드의 동등한 잔기는 치환될 수 있다. 또 다른 구체적인 실시예에서, 녹농균 아주린(서열번호:1)의 57번 아미노산 잔기에 있는 글루타민 잔기, 또는 또 다른 큐프레독신 유래 펩타이드의 동등한 잔기는 치환될 수 있고, 더 구체적으로 트립토판으로 치환될 수 있다. 또 다른 구체적인 실시예에서, 녹농균 아주린(서열번호:1)의 52번 아미노산 잔기에 있는 트레오닌 잔기, 또는 또 다른 큐프레독신 유래 펩타이드의 동등한 잔기는 치환될 수 있고, 더 구체적으로 트립토판으로 치환될 수 있다. 또 다른 구체적인 실시예에서, 녹농균 아주린(서열번호:1)의 61번 아미노산 잔기에 있는 트레오닌 잔기, 또는 또 다른 큐프레독신 유래 펩타이드의 동등한 잔기는 치환될 수 있고, 더 구체적으로 트립토판으로 치환될 수 있다. 또 다른 구체적인 실시예에서, 녹농균 아주린(서열번호:1)의 63번 아미노산 잔기에 있는 글리신 잔기, 또는 또 다른 큐프레독신 유래 펩타이드의 동등한 잔기는 치환될 수 있고, 더 구체적으로 트립토판으로 치환될 수 있다. 또 다른 구체적인 실시예에서, 녹농균 아주린(서열번호:1)의 52번, 57번, 61번 또는 63번 아미노산 잔기에 있는 하나 이상의 트레오닌 잔기, 글루타민 또는 글리신 잔기, 또는 또 다른 큐프레독신 유래 펩타이드의 동등한 잔기는 치환될 수 있고, 더 구체적으로 트립토판으로 치환될 수 있다. 구체적인 실시예에서, 상기 큐프레독신 펩타이드는 다음 서열 중 하나를 포함하며, 이 때 밑줄그은 아미노산은 야생형 녹농균 아주린 서열로 치환된다:
LSWAADMQGVVTDGMASGLDKDYLKPDD (서열번호:34);
LSTAADMWGVVTDGMASGLDKDYLKPDD (서열번호:35);
LSTAADMQGVVWDGMASGLDKDYLKPDD (서열번호:36);
LSTAADMQGVVTDWMASGLDKDYLKPDD (서열번호:37);
LSWAADMWGVVTDGMASGLDKDYLKPDD (서열번호:38);
LSWAADMQGVVWDGMASGLDKDYLKPDD (서열번호:39);
LSWAADMQGVVTDWMASGLDKDYLKPDD (서열번호:40);
LSTAADMWGVVWDGMASGLDKDYLKPDD (서열번호:41);
LSTAADMWGVVTDWMASGLDKDYLKPDD (서열번호:42);
LSTAADMQGVVWDWMASGLDKDYLKPDD (서열번호:43); 또는
LSWAADMWGVVWDWMASGLDKDYLKPDD (서열번호:44).
다른 실시예에서, 다른 큐프레독신 유래 펩타이드에 동등한 아미노산은 트립토판으로 치환된다.
α-나선 3차 구조를 안정화하기 위한 또 다른 방법은 π-스택킹(stacking)을 가능하게 하는 비-천연 아미노산 잔기의 사용을 수반한다. 예를 들어, Andrews 및 Tabor(Tetrahedron 55:11711-11743 (1999))의 문헌에서, ε-(3,5-디니트로벤조일)-Lys 잔기의 쌍은 다른 간격으로 펩타이드의 α-나선 영역에 치환되었다. 전체적인 결과는 i(i+4) 간격이 가장 효과적인 안정화 배열이라는 것을 밝혔다. 물의 비율을 최대 90 %까지 증가시키는 것은 펩타이드의 나선 함량을 높였다. 동일한 i(i+4) 간격의 ε-아실-Lys 잔기의 쌍은 안정화 효과를 갖지 않으며, 이는 안정화의 대부분이 π-π 상호작용으로부터 발생한다는 것을 나타낸다. 일부 실시예에서, 큐프레독신 유래 펩타이드는 리신 잔기가 ε-(3,5-디니트로벤조일)-Lys 잔기에 의해 치환되도록 변형될 수 있다. 구체적 실시예에서, 상기 리신 잔기는 i(i+4) 간격으로 ε-(3,5-디니트로벤조일)-Lys 잔기에 의해 치환될 수 있다.
α-나선 3차 구조를 안정화하기 위한 또 다른 방법은 α-나선 중의 측쇄 간의 정전기적 상호작용을 사용한다. His-Cys 또는 His-His 잔기 쌍이 i(i+4) 배열로 펩타이드 안에 치환되었다면, 상기 펩타이드는 Cu, Zn 또는 Cd 이온의 첨가에 대하여 약 50 % 나선형으로부터 약 90 % 나선형으로 변했다. 루테늄(Ru) 염이 His-His 펩타이드에 첨가되면, 교환-비활성 복합체는 대환식(macrocyclic) cis[Ru-(NH3)4L2]3+ 복합체를 형성했으며, 상기 L2는 나선 안정성을 개선하는 두 개의 히스티딘의 측쇄이다(Ghadiri 및 Fernholz, J. Am. Chem. Soc. 112, 9633-9635 (1990)). 일부 실시예에서, 큐프레독신 유래 펩타이드는 대환식(macrocyclic) cis[Ru-(NH3)4L2]3+ 복합체를 포함할 수 있으며, 상기 L2는 두 개의 히스티딘이다. 일부 실시예에서, 하나 이상의 히스티딘-시스테인 또는 히스티딘-히스티딘 잔기 쌍은 i,(i+4) 배열을 큐프레독신 유래 펩타이드의 α-나선으로 치환할 수 있다. 다른 실시예에서, 하나 이상의 히스티딘-시스테인 또는 또는 히스티딘-히스티딘 잔기 쌍은 i,(i+4) 배열을 녹농균 아주린(서열번호:1)의 53번 내지 56번, 58번 내지 64번 및 68번 내지 70번 잔기로 치환될 수 있다. 일부 실시예에서, 상기 큐프레독신유래 펩타이드는 Cu, Zn, Cd 및/또는 Ru 이온을 더 포함할 수 있다.
α-나선 3차 구조를 안정화시키기 위한 또 다른 방법은 α-나선의 측쇄 사이에서 이황화 결합 형성을 수반한다. 또한, 펩타이드 서열로 분리된 잔기 간에 공유 결합을 이용하여 나선 구조를 안정화시킬 수 있다. 보통 채용되는 자연적인 방법은 이황화 결합을 사용하는 것이다(Pierret 등, Intl. J. Pept. Prot. Res., 46:471-479 (1995)). 일부 실시예에서, 하나 이상의 시스테인 잔기 쌍은 큐프레독신 유래 펩타이드의 α-나선 안으로 치환된다. 다른 실시예에서, 하나 이상의 시스테인 잔기 쌍은 녹농균 아주린(서열번호:1)의 53번 내지 56번, 58번 내지 64번 및 68번 내지 70번 잔기에서 치환되거나, 다른 큐프레독신 유래 펩타이드의 동등한 잔기에서 치환된다. α-나선 차 구조를 안정화하기 위한 또 다른 방법은 측쇄 락탐 브릿지의 사용을 수반한다. 락탐은 아미노산의 고리화로부터 형성될 수 있는 고리형 아미드이다. 측쇄에서 측쇄 브릿지로의 형성은 다양한 펩타이드, 및 양친매성 또는 모델 α-나선 펩타이드, 옥시토신 길항제, 멜라노트로핀 유사체, 글루카곤 및 SDF-1 펩타이드 유사체와 같은 펩타이드 유사체에서 제약하는 것으로서 성공적으로 사용되었다. 예를 들어, 글루카곤 유사 펩타이드-1(GLP-1)은 특정 나선에 유리한 조건하에서 나선 구조를 서서히 띠고, 락탐 브리징을 사용하여 안정화될 수 있다(Miranda 등, J. Med. Chem., 51, 2758-2765 (2008)). 이러한 락탐 브릿지는 크기, 안정성에 영향을 미치는 정도 및 결합 친화도가 다를 수 있다. Id. 이러한 변형은 혈장 중의 화합물의 안정성을 개선했다. Id. 고리화 위치와 잔기의 선택 사이에 간격에 따라서, 락탐 브릿지는 회전 또는 나선 구조를 유도하고 안정화하기 위해 사용될 수 있다. 일부 실시예에서, 하나 이상의 큐프레독신 또는 변이 유사체는 인접한 아미노산 사이에 락탐 브릿지을 갖도록 제조된다(예를 들어, i 내지 i+4 글루탐산-리신 제약). 일부 실시예에서, 상기 큐프레독신 유래 펩타이드는 α-나선 함량을 향상시키도록 이러한 변형을 포함할 수 있다.
α-나선 3차 구조를 안정화하기 위한 또 다른 방법은 모든 탄소가 가교결합하는 방법이다. 모든 탄소가 가교결합하는 방법은 나선 구조의 안정성, 단백질 분해 효소에 대한 저항성 및 세포 침투성을 증가시키는 것으로 증면되었다(Walensky 등, Science, 305, 1466-1470 (2004)). 올레핀-함유 테더를 함유하는 α,α-이치환된 비-천연 아미노산은 펩타이드 안에 포함된다. 루테늄으로 촉진된 올레핀 상호교환반응은 나선을 가교하기 위하여 모든 탄화수소 "스테이플(staple)"을 생성한다(Schafmeister 등, J. Am. Chem. Soc, 122, 5891-5892 (2000); Walensky 등, id..). 올레핀-함유 테더를 함유하는 비-천연 아미노산은 Schafmeister 등. (id.), 및 Williams 및 Im (J. Am. Chem. Soc, 113:9276-9286 (1991))에서 제공되는 방법론에 따라서 합성될 수 있다. 일부 실시예에서, 상기 큐프레독신 유래 펩타이드는 모든 탄화수소 스테이플에 의해 안정화된다. 구체적인 실시예에서, 천연 아미노산에 대응되는 올레핀-함유 테더를 함유하는 α,α-이치환된 비-천연 아미노산 중 하나 이상의 쌍은 큐프레독신 유래 펩타이드의 α-나선 안으로 치환된다. 다른 실시예에서, 천연 아미노산에 대응되는 올레핀-함유 테더를 함유하는 α,α-이치환된 비-천연 아미노산 중 하나 이상의 쌍은 녹농균 아주린(서열번호:1)의 53번 내지 56번, 58번 내지 64번 및 68번 내지 70번 잔기로 치환되거나, 다른 큐프레독신 유래 펩타이드의 동등한 잔기로 치환된다. 일부 실시예에서, 변형된 큐프레독신 유래 펩타이드는 X1SX2AADX3X4X5VVX6DX7X8ASGLDKDYLKPDX9(서열번호:48)을 포함할 수 있으며, 상기 X1은 L 또는 아세틸화된-L이며, X2는 T 또는 W이며, X3는 M, L 또는 V이며, X4는 Q 또는 W이며, X5는 G 또는 A이며, X6은 T 또는 W이며, X7은 G, T 또는 W이며, X8은 M, L 또는 V이고, X9는 D 또는 아미드화된-D이다. 다른 실시예에서, 변형된 큐프레독신 유래 펩타이드는 X1SX2AADX3X4X5VVX6DX7X8ASGLDKDYLKPDX9(서열번호:48)로 구성될 수 있으며, 상기 X1은 L 또는 아세틸화된-L이며, X2는 T 또는 W이며, X3는 M, L 또는 V이며, X4는 Q 또는 W이며, X5는 G 또는 A이며, X6은 T 또는 W이며, X7은 G, T 또는 W이며, X8은 M, L 또는 V이고, X9는 D 또는 아미드화된-D이다. 다른 실시예에서, 변형된 큐프레독신 유래 펩타이드는 X1DPKLYDKDLGSAX2X3DX4VVX5X6X7DAAX8SX9(서열번호:49)을 포함할 수 있으며, 상기 X1은 D 또는 아세틸화된-D이며, X2는 M, L 또는 V이며, X3는 G, T 또는 W이며, X4는 T 또는 W이며, X5는 G 또는 A이며, X6은 Q 또는 W이며, X7은 M, L 또는 V이며, X8은 T 또는 W이고, X9는 L 또는 아미드화된-L이다. 다른 실시예에서, 변형된 큐프레독신 유래 펩타이드는 X1DPKLYDKDLGSAX2X3DX4VVX5X6X7DAAX8SX9(서열번호:49)로 구성될 수 있으며, 상기 X1은 D 또는 아세틸화된-D이며, X2는 M, L 또는 V이며, X3는 G, T 또는 W이며, X4는 T 또는 W이며, X5는 G 또는 A이며, X6은 Q 또는 W이며, X7은 M, L 또는 V이며, X8은 T 또는 W이고, X9는 L 또는 아미드화된-L이다. 관심있는 구체적인 펩타이드는 표 3에 나열된다.
표 3. 변형된 큐프레독신 유래 펩타이드
*는 아세틸화를 나타낸다.
＄는 아미드화를 나타낸다.
*LSTAADMQGVVTDGMASGLDKDYLKPDD (서열번호:50)
LSWAADMQGVVTDGMASGLDKDYLKPDD (서열번호:51)
*LSWAADMQGVVTDGMASGLDKDYLKPDD (서열번호:52)
LSTAADLQGVVTDGMASGLDKDYLKPDD (서열번호:53)
*LSTAADLQGVVTDGMASGLDKDYLKPDD (서열번호:54)
LSWAADLQGVVTDGMASGLDKDYLKPDD (서열번호:55)
*LSWAADLQGVVTDGMASGLDKDYLKPDD (서열번호:56)
LSTAADVQGVVTDGMASGLDKDYLKPDD (서열번호:57)
*LSTAADVQGVVTDGMASGLDKDYLKPDD (서열번호:58)
LSWAADVQGVVTDGMASGLDKDYLKPDD (서열번호:59)
*LSWAADVQGVVTDGMASGLDKDYLKPDD (서열번호:60)
LSTAADMWGVVTDGMASGLDKDYLKPDD (서열번호:61)
*LSTAADMWGVVTDGMASGLDKDYLKPDD (서열번호:62)
LSWAADMWGVVTDGMASGLDKDYLKPDD (서열번호:63)
*LSWAADMWGVVTDGMASGLDKDYLKPDD (서열번호:64)
LSTAADLWGVVTDGMASGLDKDYLKPDD (서열번호:65)
*LSTAADLWGVVTDGMASGLDKDYLKPDD (서열번호:66)
LSWAADLWGVVTDGMASGLDKDYLKPDD (서열번호:67)
*LSWAADLWGVVTDGMASGLDKDYLKPDD (서열번호:68)
LSTAADVWGVVTDGMASGLDKDYLKPDD (서열번호:69)
*LSTAADVWGVVTDGMASGLDKDYLKPDD (서열번호:70)
LSWAADVWGVVTDGMASGLDKDYLKPDD (서열번호:71)
*LSWAADVWGVVTDGMASGLDKDYLKPDD (서열번호:72)
LSTAADMQAVVTDGMASGLDKDYLKPDD (서열번호:73)
*LSTAADMQAVVTDGMASGLDKDYLKPDD (서열번호:74)
LSWAADMQAVVTDGMASGLDKDYLKPDD (서열번호:75)
*LSWAADMQAVVTDGMASGLDKDYLKPDD (서열번호:76)
LSTAADLQAVVTDGMASGLDKDYLKPDD (서열번호:77)
*LSTAADLQAVVTDGMASGLDKDYLKPDD (서열번호:78)
LSWAADLQAVVTDGMASGLDKDYLKPDD (서열번호:79)
*LSWAADLQAVVTDGMASGLDKDYLKPDD (서열번호:80)
LSTAADVQAVVTDGMASGLDKDYLKPDD (서열번호:81)
*LSTAADVQAVVTDGMASGLDKDYLKPDD (서열번호:82)
LSWAADVQAVVTDGMASGLDKDYLKPDD (서열번호:83)
*LSWAADVQAVVTDGMASGLDKDYLKPDD (서열번호:84)
LSTAADMWAVVTDGMASGLDKDYLKPDD (서열번호:85)
*LSTAADMWAVVTDGMASGLDKDYLKPDD (서열번호:86)
LSWAADMWAVVTDGMASGLDKDYLKPDD (서열번호:87)
*LSWAADMWAVVTDGMASGLDKDYLKPDD (서열번호:88)
LSTAADLWAVVTDGMASGLDKDYLKPDD (서열번호:89)
*LSTAADLWAVVTDGMASGLDKDYLKPDD (서열번호:90)
LSWAADLWAVVTDGMASGLDKDYLKPDD (서열번호:91)
*LSWAADLWAVVTDGMASGLDKDYLKPDD (서열번호:92)
LSTAADVWAVVTDGMASGLDKDYLKPDD (서열번호:93)
*LSTAADVWAVVTDGMASGLDKDYLKPDD (서열번호:94)
LSWAADVWAVVTDGMASGLDKDYLKPDD (서열번호:95)
*LSWAADVWAVVTDGMASGLDKDYLKPDD (서열번호:96)
LSTAADMQGVVWDGMASGLDKDYLKPDD (서열번호:97)
*LSTAADMQGVVWDGMASGLDKDYLKPDD (서열번호:98)
LSWAADMQGVVWDGMASGLDKDYLKPDD (서열번호:99)
*LSWAADMQGVVWDGMASGLDKDYLKPDD (서열번호:100)
LSTAADLQGVVWDGMASGLDKDYLKPDD (서열번호:101)
*LSTAADLQGVVWDGMASGLDKDYLKPDD (서열번호:102)
LSWAADLQGVVWDGMASGLDKDYLKPDD (서열번호:103)
*LSWAADLQGVVWDGMASGLDKDYLKPDD (서열번호:104)
LSTAADVQGVVWDGMASGLDKDYLKPDD (서열번호:105)
*LSTAADVQGVVWDGMASGLDKDYLKPDD (서열번호:106)
LSWAADVQGVVWDGMASGLDKDYLKPDD (서열번호:107)
*LSWAADVQGVVWDGMASGLDKDYLKPDD (서열번호:108)
LSTAADMWGVVWDGMASGLDKDYLKPDD (서열번호:109)
*LSTAADMWGVVWDGMASGLDKDYLKPDD (서열번호:110)
LSWAADMWGVVWDGMASGLDKDYLKPDD (서열번호:111)
*LSWAADMWGVVWDGMASGLDKDYLKPDD (서열번호:112)
LSTAADLWGVVWDGMASGLDKDYLKPDD (서열번호:113)
*LSTAADLWGVVWDGMASGLDKDYLKPDD (서열번호:114)
LSWAADLWGVVWDGMASGLDKDYLKPDD (서열번호:115)
*LSWAADLWGVVWDGMASGLDKDYLKPDD (서열번호:116)
LSTAADVWGVVWDGMASGLDKDYLKPDD (서열번호:117)
*LSTAADVWGVVWDGMASGLDKDYLKPDD (서열번호:118)
LSWAADVWGVVWDGMASGLDKDYLKPDD (서열번호:119)
*LSWAADVWGVVWDGMASGLDKDYLKPDD (서열번호:120)
LSTAADMQAVVWDGMASGLDKDYLKPDD (서열번호:121)
*LSTAADMQAVVWDGMASGLDKDYLKPDD (서열번호:122)
LSWAADMQAVVWDGMASGLDKDYLKPDD (서열번호:123)
*LSWAADMQAVVWDGMASGLDKDYLKPDD (서열번호:124)
LSTAADLQAVVWDGMASGLDKDYLKPDD (서열번호:125)
*LSTAADLQAVVWDGMASGLDKDYLKPDD (서열번호:126)
LSWAADLQAVVWDGMASGLDKDYLKPDD (서열번호:127)
*LSWAADLQAVVWDGMASGLDKDYLKPDD (서열번호:128)
LSTAADVQAVVWDGMASGLDKDYLKPDD (서열번호:129)
*LSTAADVQAVVWDGMASGLDKDYLKPDD (서열번호:130)
LSWAADVQAVVWDGMASGLDKDYLKPDD (서열번호:131)
*LSWAADVQAVVWDGMASGLDKDYLKPDD (서열번호:132)
LSTAADMWAVVWDGMASGLDKDYLKPDD (서열번호:133)
*LSTAADMWAVVWDGMASGLDKDYLKPDD (서열번호:134)
LSWAADMWAVVWDGMASGLDKDYLKPDD (서열번호:135)
*LSWAADMWAVVWDGMASGLDKDYLKPDD (서열번호:136)
LSTAADLWAVVWDGMASGLDKDYLKPDD (서열번호:137)
*LSTAADLWAVVWDGMASGLDKDYLKPDD (서열번호:138)
LSWAADLWAVVWDGMASGLDKDYLKPDD (서열번호:139)
*LSWAADLWAVVWDGMASGLDKDYLKPDD (서열번호:140)
LSTAADVWAVVWDGMASGLDKDYLKPDD (서열번호:141)
*LSTAADVWAVVWDGMASGLDKDYLKPDD (서열번호:142)
LSWAADVWAVVWDGMASGLDKDYLKPDD (서열번호:143)
*LSWAADVWAVVWDGMASGLDKDYLKPDD (서열번호:144)
LSTAADMQGVVTDTMASGLDKDYLKPDD (서열번호:145)
*LSTAADMQGVVTDTMASGLDKDYLKPDD (서열번호:146)
LSWAADMQGVVTDTMASGLDKDYLKPDD (서열번호:147)
*LSWAADMQGVVTDTMASGLDKDYLKPDD (서열번호:148)
LSTAADLQGVVTDTMASGLDKDYLKPDD (서열번호:149)
*LSTAADLQGVVTDTMASGLDKDYLKPDD (서열번호:150)
LSWAADLQGVVTDTMASGLDKDYLKPDD (서열번호:151)
*LSWAADLQGVVTDTMASGLDKDYLKPDD (서열번호:152)
LSTAADVQGVVTDTMASGLDKDYLKPDD (서열번호:153)
*LSTAADVQGVVTDTMASGLDKDYLKPDD (서열번호:154)
LSWAADVQGVVTDTMASGLDKDYLKPDD (서열번호:155)
*LSWAADVQGVVTDTMASGLDKDYLKPDD (서열번호:156)
LSTAADMWGVVTDTMASGLDKDYLKPDD (서열번호:157)
*LSTAADMWGVVTDTMASGLDKDYLKPDD (서열번호:158)
LSWAADMWGVVTDTMASGLDKDYLKPDD (서열번호:159)
*LSWAADMWGVVTDTMASGLDKDYLKPDD (서열번호:160)
LSTAADLWGVVTDTMASGLDKDYLKPDD (서열번호:161)
*LSTAADLWGVVTDTMASGLDKDYLKPDD (서열번호:162)
LSWAADLWGVVTDTMASGLDKDYLKPDD (서열번호:163)
*LSWAADLWGVVTDTMASGLDKDYLKPDD (서열번호:164)
LSTAADVWGVVTDTMASGLDKDYLKPDD (서열번호:165)
*LSTAADVWGVVTDTMASGLDKDYLKPDD (서열번호:166)
LSWAADVWGVVTDTMASGLDKDYLKPDD (서열번호:167)
*LSWAADVWGVVTDTMASGLDKDYLKPDD (서열번호:168)
LSTAADMQAVVTDTMASGLDKDYLKPDD (서열번호:169)
*LSTAADMQAVVTDTMASGLDKDYLKPDD (서열번호:170)
LSWAADMQAVVTDTMASGLDKDYLKPDD (서열번호:171)
*LSWAADMQAVVTDTMASGLDKDYLKPDD (서열번호:172)
LSTAADLQAVVTDTMASGLDKDYLKPDD (서열번호:173)
*LSTAADLQAVVTDTMASGLDKDYLKPDD (서열번호:174)
LSWAADLQAVVTDTMASGLDKDYLKPDD (서열번호:175)
*LSWAADLQAVVTDTMASGLDKDYLKPDD (서열번호:176)
LSTAADVQAVVTDTMASGLDKDYLKPDD (서열번호:177)
*LSTAADVQAVVTDTMASGLDKDYLKPDD (서열번호:178)
LSWAADVQAVVTDTMASGLDKDYLKPDD (서열번호:179)
*LSWAADVQAVVTDTMASGLDKDYLKPDD (서열번호:180)
LSTAADMWAVVTDTMASGLDKDYLKPDD (서열번호:181)
*LSTAADMWAVVTDTMASGLDKDYLKPDD (서열번호:182)
LSWAADMWAVVTDTMASGLDKDYLKPDD (서열번호:183)
*LSWAADMWAVVTDTMASGLDKDYLKPDD (서열번호:184)
LSTAADLWAVVTDTMASGLDKDYLKPDD (서열번호:185)
*LSTAADLWAVVTDTMASGLDKDYLKPDD (서열번호:186)
LSWAADLWAVVTDTMASGLDKDYLKPDD (서열번호:187)
*LSWAADLWAVVTDTMASGLDKDYLKPDD (서열번호:188)
LSTAADVWAVVTDTMASGLDKDYLKPDD (서열번호:189)
*LSTAADVWAVVTDTMASGLDKDYLKPDD (서열번호:190)
LSWAADVWAVVTDTMASGLDKDYLKPDD (서열번호:191)
*LSWAADVWAVVTDTMASGLDKDYLKPDD (서열번호:192)
LSTAADMQGVVWDTMASGLDKDYLKPDD (서열번호:193)
*LSTAADMQGVVWDTMASGLDKDYLKPDD (서열번호:194)
LSWAADMQGVVWDTMASGLDKDYLKPDD (서열번호:195)
*LSWAADMQGVVWDTMASGLDKDYLKPDD (서열번호:196)
LSTAADLQGVVWDTMASGLDKDYLKPDD (서열번호:197)
*LSTAADLQGVVWDTMASGLDKDYLKPDD (서열번호:198)
LSWAADLQGVVWDTMASGLDKDYLKPDD (서열번호:199)
*LSWAADLQGVVWDTMASGLDKDYLKPDD (서열번호:200)
LSTAADVQGVVWDTMASGLDKDYLKPDD (서열번호:201)
*LSTAADVQGVVWDTMASGLDKDYLKPDD (서열번호:202)
LSWAADVQGVVWDTMASGLDKDYLKPDD (서열번호:203)
*LSWAADVQGVVWDTMASGLDKDYLKPDD (서열번호:204)
LSTAADMWGVVWDTMASGLDKDYLKPDD (서열번호:205)
*LSTAADMWGVVWDTMASGLDKDYLKPDD (서열번호:206)
LSWAADMWGVVWDTMASGLDKDYLKPDD (서열번호:207)
*LSWAADMWGVVWDTMASGLDKDYLKPDD (서열번호:208)
LSTAADLWGVVWDTMASGLDKDYLKPDD (서열번호:209)
*LSTAADLWGVVWDTMASGLDKDYLKPDD (서열번호:210)
LSWAADLWGVVWDTMASGLDKDYLKPDD (서열번호:211)
*LSWAADLWGVVWDTMASGLDKDYLKPDD (서열번호:212)
LSTAADVWGVVWDTMASGLDKDYLKPDD (서열번호:213)
*LSTAADVWGVVWDTMASGLDKDYLKPDD (서열번호:214)
LSWAADVWGVVWDTMASGLDKDYLKPDD (서열번호:215)
*LSWAADVWGVVWDTMASGLDKDYLKPDD (서열번호:216)
LSTAADMQAVVWDTMASGLDKDYLKPDD (서열번호:217)
*LSTAADMQAVVWDTMASGLDKDYLKPDD (서열번호:218)
LSWAADMQAVVWDTMASGLDKDYLKPDD (서열번호:219)
*LSWAADMQAVVWDTMASGLDKDYLKPDD (서열번호:220)
LSTAADLQAVVWDTMASGLDKDYLKPDD (서열번호:221)
*LSTAADLQAVVWDTMASGLDKDYLKPDD (서열번호:222)
LSWAADLQAVVWDTMASGLDKDYLKPDD (서열번호:223)
*LSWAADLQAVVWDTMASGLDKDYLKPDD (서열번호:224)
LSTAADVQAVVWDTMASGLDKDYLKPDD (서열번호:225)
*LSTAADVQAVVWDTMASGLDKDYLKPDD (서열번호:226)
LSWAADVQAVVWDTMASGLDKDYLKPDD (서열번호:227)
*LSWAADVQAVVWDTMASGLDKDYLKPDD (서열번호:228)
LSTAADMWAVVWDTMASGLDKDYLKPDD (서열번호:229)
*LSTAADMWAVVWDTMASGLDKDYLKPDD (서열번호:230)
LSWAADMWAVVWDTMASGLDKDYLKPDD (서열번호:231)
*LSWAADMWAVVWDTMASGLDKDYLKPDD (서열번호:232)
LSTAADLWAVVWDTMASGLDKDYLKPDD (서열번호:233)
*LSTAADLWAVVWDTMASGLDKDYLKPDD (서열번호:234)
LSWAADLWAVVWDTMASGLDKDYLKPDD (서열번호:235)
*LSWAADLWAVVWDTMASGLDKDYLKPDD (서열번호:236)
LSTAADVWAVVWDTMASGLDKDYLKPDD (서열번호:237)
*LSTAADVWAVVWDTMASGLDKDYLKPDD (서열번호:238)
LSWAADVWAVVWDTMASGLDKDYLKPDD (서열번호:239)
*LSWAADVWAVVWDTMASGLDKDYLKPDD (서열번호:240)
LSTAADMQGVVTDWMASGLDKDYLKPDD (서열번호:241)
*LSTAADMQGVVTDWMASGLDKDYLKPDD (서열번호:242)
LSWAADMQGVVTDWMASGLDKDYLKPDD (서열번호:243)
*LSWAADMQGVVTDWMASGLDKDYLKPDD (서열번호:244)
LSTAADLQGVVTDWMASGLDKDYLKPDD (서열번호:245)
*LSTAADLQGVVTDWMASGLDKDYLKPDD (서열번호:246)
LSWAADLQGVVTDWMASGLDKDYLKPDD (서열번호:247)
*LSWAADLQGVVTDWMASGLDKDYLKPDD (서열번호:248)
LSTAADVQGVVTDWMASGLDKDYLKPDD (서열번호:249)
*LSTAADVQGVVTDWMASGLDKDYLKPDD (서열번호:250)
LSWAADVQGVVTDWMASGLDKDYLKPDD (서열번호:251)
*LSWAADVQGVVTDWMASGLDKDYLKPDD (서열번호:252)
LSTAADMWGVVTDWMASGLDKDYLKPDD (서열번호:253)
*LSTAADMWGVVTDWMASGLDKDYLKPDD (서열번호:254)
LSWAADMWGVVTDWMASGLDKDYLKPDD (서열번호:255)
*LSWAADMWGVVTDWMASGLDKDYLKPDD (서열번호:256)
LSTAADLWGVVTDWMASGLDKDYLKPDD (서열번호:257)
*LSTAADLWGVVTDWMASGLDKDYLKPDD (서열번호:258)
LSWAADLWGVVTDWMASGLDKDYLKPDD (서열번호:259)
*LSWAADLWGVVTDWMASGLDKDYLKPDD (서열번호:260)
LSTAADVWGVVTDWMASGLDKDYLKPDD (서열번호:261)
*LSTAADVWGVVTDWMASGLDKDYLKPDD (서열번호:262)
LSWAADVWGVVTDWMASGLDKDYLKPDD (서열번호:263)
*LSWAADVWGVVTDWMASGLDKDYLKPDD (서열번호:264)
LSTAADMQAVVTDWMASGLDKDYLKPDD (서열번호:265)
*LSTAADMQAVVTDWMASGLDKDYLKPDD (서열번호:266)
LSWAADMQAVVTDWMASGLDKDYLKPDD (서열번호:267)
*LSWAADMQAVVTDWMASGLDKDYLKPDD (서열번호:268)
LSTAADLQAVVTDWMASGLDKDYLKPDD (서열번호:269)
*LSTAADLQAVVTDWMASGLDKDYLKPDD (서열번호:270)
LSWAADLQAVVTDWMASGLDKDYLKPDD (서열번호:271)
*LSWAADLQAVVTDWMASGLDKDYLKPDD (서열번호:272)
LSTAADVQAVVTDWMASGLDKDYLKPDD (서열번호:273)
*LSTAADVQAVVTDWMASGLDKDYLKPDD (서열번호:274)
LSWAADVQAVVTDWMASGLDKDYLKPDD (서열번호:275)
*LSWAADVQAVVTDWMASGLDKDYLKPDD (서열번호:276)
LSTAADMWAVVTDWMASGLDKDYLKPDD (서열번호:277)
*LSTAADMWAVVTDWMASGLDKDYLKPDD (서열번호:278)
LSWAADMWAVVTDWMASGLDKDYLKPDD (서열번호:279)
*LSWAADMWAVVTDWMASGLDKDYLKPDD (서열번호:280)
LSTAADLWAVVTDWMASGLDKDYLKPDD (서열번호:281)
*LSTAADLWAVVTDWMASGLDKDYLKPDD (서열번호:282)
LSWAADLWAVVTDWMASGLDKDYLKPDD (서열번호:283)
*LSWAADLWAVVTDWMASGLDKDYLKPDD (서열번호:284)
LSTAADVWAVVTDWMASGLDKDYLKPDD (서열번호:285)
*LSTAADVWAVVTDWMASGLDKDYLKPDD (서열번호:286)
LSWAADVWAVVTDWMASGLDKDYLKPDD (서열번호:287)
*LSWAADVWAVVTDWMASGLDKDYLKPDD (서열번호:288)
LSTAADMQGVVWDWMASGLDKDYLKPDD (서열번호:289)
*LSTAADMQGVVWDWMASGLDKDYLKPDD (서열번호:290)
LSWAADMQGVVWDWMASGLDKDYLKPDD (서열번호:291)
*LSWAADMQGVVWDWMASGLDKDYLKPDD (서열번호:292)
LSTAADLQGVVWDWMASGLDKDYLKPDD (서열번호:293)
*LSTAADLQGVVWDWMASGLDKDYLKPDD (서열번호:294)
LSWAADLQGVVWDWMASGLDKDYLKPDD (서열번호:295)
*LSWAADLQGVVWDWMASGLDKDYLKPDD (서열번호:296)
LSTAADVQGVVWDWMASGLDKDYLKPDD (서열번호:297)
*LSTAADVQGVVWDWMASGLDKDYLKPDD (서열번호:298)
LSWAADVQGVVWDWMASGLDKDYLKPDD (서열번호:299)
*LSWAADVQGVVWDWMASGLDKDYLKPDD (서열번호:300)
LSTAADMWGVVWDWMASGLDKDYLKPDD (서열번호:301)
*LSTAADMWGVVWDWMASGLDKDYLKPDD (서열번호:302)
LSWAADMWGVVWDWMASGLDKDYLKPDD (서열번호:303)
*LSWAADMWGVVWDWMASGLDKDYLKPDD (서열번호:304)
LSTAADLWGVVWDWMASGLDKDYLKPDD (서열번호:305)
*LSTAADLWGVVWDWMASGLDKDYLKPDD (서열번호:306)
LSWAADLWGVVWDWMASGLDKDYLKPDD (서열번호:307)
*LSWAADLWGVVWDWMASGLDKDYLKPDD (서열번호:308)
LSTAADVWGVVWDWMASGLDKDYLKPDD (서열번호:309)
*LSTAADVWGVVWDWMASGLDKDYLKPDD (서열번호:310)
LSWAADVWGVVWDWMASGLDKDYLKPDD (서열번호:311)
*LSWAADVWGVVWDWMASGLDKDYLKPDD (서열번호:312)
LSTAADMQAVVWDWMASGLDKDYLKPDD (서열번호:313)
*LSTAADMQAVVWDWMASGLDKDYLKPDD (서열번호:314)
LSWAADMQAVVWDWMASGLDKDYLKPDD (서열번호:315)
*LSWAADMQAVVWDWMASGLDKDYLKPDD (서열번호:316)
LSTAADLQAVVWDWMASGLDKDYLKPDD (서열번호:317)
*LSTAADLQAVVWDWMASGLDKDYLKPDD (서열번호:318)
LSWAADLQAVVWDWMASGLDKDYLKPDD (서열번호:319)
*LSWAADLQAVVWDWMASGLDKDYLKPDD (서열번호:320)
LSTAADVQAVVWDWMASGLDKDYLKPDD (서열번호:321)
*LSTAADVQAVVWDWMASGLDKDYLKPDD (서열번호:322)
LSWAADVQAVVWDWMASGLDKDYLKPDD (서열번호:323)
*LSWAADVQAVVWDWMASGLDKDYLKPDD (서열번호:324)
LSTAADMWAVVWDWMASGLDKDYLKPDD (서열번호:325)
*LSTAADMWAVVWDWMASGLDKDYLKPDD (서열번호:326)
LSWAADMWAVVWDWMASGLDKDYLKPDD (서열번호:327)
*LSWAADMWAVVWDWMASGLDKDYLKPDD (서열번호:328)
LSTAADLWAVVWDWMASGLDKDYLKPDD (서열번호:329)
*LSTAADLWAVVWDWMASGLDKDYLKPDD (서열번호:330)
LSWAADLWAVVWDWMASGLDKDYLKPDD (서열번호:331)
*LSWAADLWAVVWDWMASGLDKDYLKPDD (서열번호:332)
LSTAADVWAVVWDWMASGLDKDYLKPDD (서열번호:333)
*LSTAADVWAVVWDWMASGLDKDYLKPDD (서열번호:334)
LSWAADVWAVVWDWMASGLDKDYLKPDD (서열번호:335)
*LSWAADVWAVVWDWMASGLDKDYLKPDD (서열번호:336)
LSTAADMQGVVTDGLASGLDKDYLKPDD (서열번호:337)
*LSTAADMQGVVTDGLASGLDKDYLKPDD (서열번호:338)
LSWAADMQGVVTDGLASGLDKDYLKPDD (서열번호:339)
*LSWAADMQGVVTDGLASGLDKDYLKPDD (서열번호:340)
LSTAADLQGVVTDGLASGLDKDYLKPDD (서열번호:341)
*LSTAADLQGVVTDGLASGLDKDYLKPDD (서열번호:342)
LSWAADLQGVVTDGLASGLDKDYLKPDD (서열번호:343)
*LSWAADLQGVVTDGLASGLDKDYLKPDD (서열번호:344)
LSTAADVQGVVTDGLASGLDKDYLKPDD (서열번호:345)
*LSTAADVQGVVTDGLASGLDKDYLKPDD (서열번호:346)
LSWAADVQGVVTDGLASGLDKDYLKPDD (서열번호:347)
*LSWAADVQGVVTDGLASGLDKDYLKPDD (서열번호:348)
LSTAADMWGVVTDGLASGLDKDYLKPDD (서열번호:349)
*LSTAADMWGVVTDGLASGLDKDYLKPDD (서열번호:350)
LSWAADMWGVVTDGLASGLDKDYLKPDD (서열번호:351)
*LSWAADMWGVVTDGLASGLDKDYLKPDD (서열번호:352)
LSTAADLWGVVTDGLASGLDKDYLKPDD (서열번호:353)
*LSTAADLWGVVTDGLASGLDKDYLKPDD (서열번호:354)
LSWAADLWGVVTDGLASGLDKDYLKPDD (서열번호:355)
*LSWAADLWGVVTDGLASGLDKDYLKPDD (서열번호:356)
LSTAADVWGVVTDGLASGLDKDYLKPDD (서열번호:357)
*LSTAADVWGVVTDGLASGLDKDYLKPDD (서열번호:358)
LSWAADVWGVVTDGLASGLDKDYLKPDD (서열번호:359)
*LSWAADVWGVVTDGLASGLDKDYLKPDD (서열번호:360)
LSTAADMQAVVTDGLASGLDKDYLKPDD (서열번호:361)
*LSTAADMQAVVTDGLASGLDKDYLKPDD (서열번호:362)
LSWAADMQAVVTDGLASGLDKDYLKPDD (서열번호:363)
*LSWAADMQAVVTDGLASGLDKDYLKPDD (서열번호:364)
LSTAADLQAVVTDGLASGLDKDYLKPDD (서열번호:365)
*LSTAADLQAVVTDGLASGLDKDYLKPDD (서열번호:366)
LSWAADLQAVVTDGLASGLDKDYLKPDD (서열번호:367)
*LSWAADLQAVVTDGLASGLDKDYLKPDD (서열번호:368)
LSTAADVQAVVTDGLASGLDKDYLKPDD (서열번호:369)
*LSTAADVQAVVTDGLASGLDKDYLKPDD (서열번호:370)
LSWAADVQAVVTDGLASGLDKDYLKPDD (서열번호:371)
*LSWAADVQAVVTDGLASGLDKDYLKPDD (서열번호:372)
LSTAADMWAVVTDGLASGLDKDYLKPDD (서열번호:373)
*LSTAADMWAVVTDGLASGLDKDYLKPDD (서열번호:374)
LSWAADMWAVVTDGLASGLDKDYLKPDD (서열번호:375)
*LSWAADMWAVVTDGLASGLDKDYLKPDD (서열번호:376)
LSTAADLWAVVTDGLASGLDKDYLKPDD (서열번호:377)
*LSTAADLWAVVTDGLASGLDKDYLKPDD (서열번호:378)
LSWAADLWAVVTDGLASGLDKDYLKPDD (서열번호:379)
*LSWAADLWAVVTDGLASGLDKDYLKPDD (서열번호:380)
LSTAADVWAVVTDGLASGLDKDYLKPDD (서열번호:381)
*LSTAADVWAVVTDGLASGLDKDYLKPDD (서열번호:382)
LSWAADVWAVVTDGLASGLDKDYLKPDD (서열번호:383)
*LSWAADVWAVVTDGLASGLDKDYLKPDD (서열번호:384)
LSTAADMQGVVWDGLASGLDKDYLKPDD (서열번호:385)
*LSTAADMQGVVWDGLASGLDKDYLKPDD (서열번호:386)
LSWAADMQGVVWDGLASGLDKDYLKPDD (서열번호:387)
*LSWAADMQGVVWDGLASGLDKDYLKPDD (서열번호:388)
LSTAADLQGVVWDGLASGLDKDYLKPDD (서열번호:389)
*LSTAADLQGVVWDGLASGLDKDYLKPDD (서열번호:390)
LSWAADLQGVVWDGLASGLDKDYLKPDD (서열번호:391)
*LSWAADLQGVVWDGLASGLDKDYLKPDD (서열번호:392)
LSTAADVQGVVWDGLASGLDKDYLKPDD (서열번호:393)
*LSTAADVQGVVWDGLASGLDKDYLKPDD (서열번호:394)
LSWAADVQGVVWDGLASGLDKDYLKPDD (서열번호:395)
*LSWAADVQGVVWDGLASGLDKDYLKPDD (서열번호:396)
LSTAADMWGVVWDGLASGLDKDYLKPDD (서열번호:397)
*LSTAADMWGVVWDGLASGLDKDYLKPDD (서열번호:398)
LSWAADMWGVVWDGLASGLDKDYLKPDD (서열번호:399)
*LSWAADMWGVVWDGLASGLDKDYLKPDD (서열번호:400)
LSTAADLWGVVWDGLASGLDKDYLKPDD (서열번호:401)
*LSTAADLWGVVWDGLASGLDKDYLKPDD (서열번호:402)
LSWAADLWGVVWDGLASGLDKDYLKPDD (서열번호:403)
*LSWAADLWGVVWDGLASGLDKDYLKPDD (서열번호:404)
LSTAADVWGVVWDGLASGLDKDYLKPDD (서열번호:405)
*LSTAADVWGVVWDGLASGLDKDYLKPDD (서열번호:406)
LSWAADVWGVVWDGLASGLDKDYLKPDD (서열번호:407)
*LSWAADVWGVVWDGLASGLDKDYLKPDD (서열번호:408)
LSTAADMQAVVWDGLASGLDKDYLKPDD (서열번호:409)
*LSTAADMQAVVWDGLASGLDKDYLKPDD (서열번호:410)
LSWAADMQAVVWDGLASGLDKDYLKPDD (서열번호:411)
*LSWAADMQAVVWDGLASGLDKDYLKPDD (서열번호:412)
LSTAADLQAVVWDGLASGLDKDYLKPDD (서열번호:413)
*LSTAADLQAVVWDGLASGLDKDYLKPDD (서열번호:414)
LSWAADLQAVVWDGLASGLDKDYLKPDD (서열번호:415)
*LSWAADLQAVVWDGLASGLDKDYLKPDD (서열번호:416)
LSTAADVQAVVWDGLASGLDKDYLKPDD (서열번호:417)
*LSTAADVQAVVWDGLASGLDKDYLKPDD (서열번호:418)
LSWAADVQAVVWDGLASGLDKDYLKPDD (서열번호:419)
*LSWAADVQAVVWDGLASGLDKDYLKPDD (서열번호:420)
LSTAADMWAVVWDGLASGLDKDYLKPDD (서열번호:421)
*LSTAADMWAVVWDGLASGLDKDYLKPDD (서열번호:422)
LSWAADMWAVVWDGLASGLDKDYLKPDD (서열번호:423)
*LSWAADMWAVVWDGLASGLDKDYLKPDD (서열번호:424)
LSTAADLWAVVWDGLASGLDKDYLKPDD (서열번호:425)
*LSTAADLWAVVWDGLASGLDKDYLKPDD (서열번호:426)
LSWAADLWAVVWDGLASGLDKDYLKPDD (서열번호:427)
*LSWAADLWAVVWDGLASGLDKDYLKPDD (서열번호:428)
LSTAADVWAVVWDGLASGLDKDYLKPDD (서열번호:429)
*LSTAADVWAVVWDGLASGLDKDYLKPDD (서열번호:430)
LSWAADVWAVVWDGLASGLDKDYLKPDD (서열번호:431)
*LSWAADVWAVVWDGLASGLDKDYLKPDD (서열번호:432)
LSTAADMQGVVTDTLASGLDKDYLKPDD (서열번호:433)
*LSTAADMQGVVTDTLASGLDKDYLKPDD (서열번호:434)
LSWAADMQGVVTDTLASGLDKDYLKPDD (서열번호:435)
*LSWAADMQGVVTDTLASGLDKDYLKPDD (서열번호:436)
LSTAADLQGVVTDTLASGLDKDYLKPDD (서열번호:437)
*LSTAADLQGVVTDTLASGLDKDYLKPDD (서열번호:438)
LSWAADLQGVVTDTLASGLDKDYLKPDD (서열번호:439)
*LSWAADLQGVVTDTLASGLDKDYLKPDD (서열번호:440)
LSTAADVQGVVTDTLASGLDKDYLKPDD (서열번호:441)
*LSTAADVQGVVTDTLASGLDKDYLKPDD (서열번호:442)
LSWAADVQGVVTDTLASGLDKDYLKPDD (서열번호:443)
*LSWAADVQGVVTDTLASGLDKDYLKPDD (서열번호:444)
LSTAADMWGVVTDTLASGLDKDYLKPDD (서열번호:445)
*LSTAADMWGVVTDTLASGLDKDYLKPDD (서열번호:446)
LSWAADMWGVVTDTLASGLDKDYLKPDD (서열번호:447)
*LSWAADMWGVVTDTLASGLDKDYLKPDD (서열번호:448)
LSTAADLWGVVTDTLASGLDKDYLKPDD (서열번호:449)
*LSTAADLWGVVTDTLASGLDKDYLKPDD (서열번호:450)
LSWAADLWGVVTDTLASGLDKDYLKPDD (서열번호:451)
*LSWAADLWGVVTDTLASGLDKDYLKPDD (서열번호:452)
LSTAADVWGVVTDTLASGLDKDYLKPDD (서열번호:453)
*LSTAADVWGVVTDTLASGLDKDYLKPDD (서열번호:454)
LSWAADVWGVVTDTLASGLDKDYLKPDD (서열번호:455)
*LSWAADVWGVVTDTLASGLDKDYLKPDD (서열번호:456)
LSTAADMQAVVTDTLASGLDKDYLKPDD (서열번호:457)
*LSTAADMQAVVTDTLASGLDKDYLKPDD (서열번호:458)
LSWAADMQAVVTDTLASGLDKDYLKPDD (서열번호:459)
*LSWAADMQAVVTDTLASGLDKDYLKPDD (서열번호:460)
LSTAADLQAVVTDTLASGLDKDYLKPDD (서열번호:461)
*LSTAADLQAVVTDTLASGLDKDYLKPDD (서열번호:462)
LSWAADLQAVVTDTLASGLDKDYLKPDD (서열번호:463)
*LSWAADLQAVVTDTLASGLDKDYLKPDD (서열번호:464)
LSTAADVQAVVTDTLASGLDKDYLKPDD (서열번호:465)
*LSTAADVQAVVTDTLASGLDKDYLKPDD (서열번호:466)
LSWAADVQAVVTDTLASGLDKDYLKPDD (서열번호:467)
*LSWAADVQAVVTDTLASGLDKDYLKPDD (서열번호:468)
LSTAADMWAVVTDTLASGLDKDYLKPDD (서열번호:469)
*LSTAADMWAVVTDTLASGLDKDYLKPDD (서열번호:470)
LSWAADMWAVVTDTLASGLDKDYLKPDD (서열번호:471)
*LSWAADMWAVVTDTLASGLDKDYLKPDD (서열번호:472)
LSTAADLWAVVTDTLASGLDKDYLKPDD (서열번호:473)
*LSTAADLWAVVTDTLASGLDKDYLKPDD (서열번호:474)
LSWAADLWAVVTDTLASGLDKDYLKPDD (서열번호:475)
*LSWAADLWAVVTDTLASGLDKDYLKPDD (서열번호:476)
LSTAADVWAVVTDTLASGLDKDYLKPDD (서열번호:477)
*LSTAADVWAVVTDTLASGLDKDYLKPDD (서열번호:478)
LSWAADVWAVVTDTLASGLDKDYLKPDD (서열번호:479)
*LSWAADVWAVVTDTLASGLDKDYLKPDD (서열번호:480)
LSTAADMQGVVWDTLASGLDKDYLKPDD (서열번호:481)
*LSTAADMQGVVWDTLASGLDKDYLKPDD (서열번호:482)
LSWAADMQGVVWDTLASGLDKDYLKPDD (서열번호:483)
*LSWAADMQGVVWDTLASGLDKDYLKPDD (서열번호:484)
LSTAADLQGVVWDTLASGLDKDYLKPDD (서열번호:485)
*LSTAADLQGVVWDTLASGLDKDYLKPDD (서열번호:486)
LSWAADLQGVVWDTLASGLDKDYLKPDD (서열번호:487)
*LSWAADLQGVVWDTLASGLDKDYLKPDD (서열번호:488)
LSTAADVQGVVWDTLASGLDKDYLKPDD (서열번호:489)
*LSTAADVQGVVWDTLASGLDKDYLKPDD (서열번호:490)
LSWAADVQGVVWDTLASGLDKDYLKPDD (서열번호:491)
*LSWAADVQGVVWDTLASGLDKDYLKPDD (서열번호:492)
LSTAADMWGVVWDTLASGLDKDYLKPDD (서열번호:493)
*LSTAADMWGVVWDTLASGLDKDYLKPDD (서열번호:494)
LSWAADMWGVVWDTLASGLDKDYLKPDD (서열번호:495)
*LSWAADMWGVVWDTLASGLDKDYLKPDD (서열번호:496)
LSTAADLWGVVWDTLASGLDKDYLKPDD (서열번호:497)
*LSTAADLWGVVWDTLASGLDKDYLKPDD (서열번호:498)
LSWAADLWGVVWDTLASGLDKDYLKPDD (서열번호:499)
*LSWAADLWGVVWDTLASGLDKDYLKPDD (서열번호:500)
LSTAADVWGVVWDTLASGLDKDYLKPDD (서열번호:501)
*LSTAADVWGVVWDTLASGLDKDYLKPDD (서열번호:502)
LSWAADVWGVVWDTLASGLDKDYLKPDD (서열번호:503)
*LSWAADVWGVVWDTLASGLDKDYLKPDD (서열번호:504)
LSTAADMQAVVWDTLASGLDKDYLKPDD (서열번호:505)
*LSTAADMQAVVWDTLASGLDKDYLKPDD (서열번호:506)
LSWAADMQAVVWDTLASGLDKDYLKPDD (서열번호:507)
*LSWAADMQAVVWDTLASGLDKDYLKPDD (서열번호:508)
LSTAADLQAVVWDTLASGLDKDYLKPDD (서열번호:509)
*LSTAADLQAVVWDTLASGLDKDYLKPDD (서열번호:510)
LSWAADLQAVVWDTLASGLDKDYLKPDD (서열번호:511)
*LSWAADLQAVVWDTLASGLDKDYLKPDD (서열번호:512)
LSTAADVQAVVWDTLASGLDKDYLKPDD (서열번호:513)
*LSTAADVQAVVWDTLASGLDKDYLKPDD (서열번호:514)
LSWAADVQAVVWDTLASGLDKDYLKPDD (서열번호:515)
*LSWAADVQAVVWDTLASGLDKDYLKPDD (서열번호:516)
LSTAADMWAVVWDTLASGLDKDYLKPDD (서열번호:517)
*LSTAADMWAVVWDTLASGLDKDYLKPDD (서열번호:518)
LSWAADMWAVVWDTLASGLDKDYLKPDD (서열번호:519)
*LSWAADMWAVVWDTLASGLDKDYLKPDD (서열번호:520)
LSTAADLWAVVWDTLASGLDKDYLKPDD (서열번호:521)
*LSTAADLWAVVWDTLASGLDKDYLKPDD (서열번호:522)
LSWAADLWAVVWDTLASGLDKDYLKPDD (서열번호:523)
*LSWAADLWAVVWDTLASGLDKDYLKPDD (서열번호:524)
LSTAADVWAVVWDTLASGLDKDYLKPDD (서열번호:525)
*LSTAADVWAVVWDTLASGLDKDYLKPDD (서열번호:526)
LSWAADVWAVVWDTLASGLDKDYLKPDD (서열번호:527)
*LSWAADVWAVVWDTLASGLDKDYLKPDD (서열번호:528)
LSTAADMQGVVTDWLASGLDKDYLKPDD (서열번호:529)
*LSTAADMQGVVTDWLASGLDKDYLKPDD (서열번호:530)
LSWAADMQGVVTDWLASGLDKDYLKPDD (서열번호:531)
*LSWAADMQGVVTDWLASGLDKDYLKPDD (서열번호:532)
LSTAADLQGVVTDWLASGLDKDYLKPDD (서열번호:533)
*LSTAADLQGVVTDWLASGLDKDYLKPDD (서열번호:534)
LSWAADLQGVVTDWLASGLDKDYLKPDD (서열번호:535)
*LSWAADLQGVVTDWLASGLDKDYLKPDD (서열번호:536)
LSTAADVQGVVTDWLASGLDKDYLKPDD (서열번호:537)
*LSTAADVQGVVTDWLASGLDKDYLKPDD (서열번호:538)
LSWAADVQGVVTDWLASGLDKDYLKPDD (서열번호:539)
*LSWAADVQGVVTDWLASGLDKDYLKPDD (서열번호:540)
LSTAADMWGVVTDWLASGLDKDYLKPDD (서열번호:541)
*LSTAADMWGVVTDWLASGLDKDYLKPDD (서열번호:542)
LSWAADMWGVVTDWLASGLDKDYLKPDD (서열번호:543)
*LSWAADMWGVVTDWLASGLDKDYLKPDD (서열번호:544)
LSTAADLWGVVTDWLASGLDKDYLKPDD (서열번호:545)
*LSTAADLWGVVTDWLASGLDKDYLKPDD (서열번호:546)
LSWAADLWGVVTDWLASGLDKDYLKPDD (서열번호:547)
*LSWAADLWGVVTDWLASGLDKDYLKPDD (서열번호:548)
LSTAADVWGVVTDWLASGLDKDYLKPDD (서열번호:549)
*LSTAADVWGVVTDWLASGLDKDYLKPDD (서열번호:550)
LSWAADVWGVVTDWLASGLDKDYLKPDD (서열번호:551)
*LSWAADVWGVVTDWLASGLDKDYLKPDD (서열번호:552)
LSTAADMQAVVTDWLASGLDKDYLKPDD (서열번호:553)
*LSTAADMQAVVTDWLASGLDKDYLKPDD (서열번호:554)
LSWAADMQAVVTDWLASGLDKDYLKPDD (서열번호:555)
*LSWAADMQAVVTDWLASGLDKDYLKPDD (서열번호:556)
LSTAADLQAVVTDWLASGLDKDYLKPDD (서열번호:557)
*LSTAADLQAVVTDWLASGLDKDYLKPDD (서열번호:558)
LSWAADLQAVVTDWLASGLDKDYLKPDD (서열번호:559)
*LSWAADLQAVVTDWLASGLDKDYLKPDD (서열번호:560)
LSTAADVQAVVTDWLASGLDKDYLKPDD (서열번호:561)
*LSTAADVQAVVTDWLASGLDKDYLKPDD (서열번호:562)
LSWAADVQAVVTDWLASGLDKDYLKPDD (서열번호:563)
*LSWAADVQAVVTDWLASGLDKDYLKPDD (서열번호:564)
LSTAADMWAVVTDWLASGLDKDYLKPDD (서열번호:565)
*LSTAADMWAVVTDWLASGLDKDYLKPDD (서열번호:566)
LSWAADMWAVVTDWLASGLDKDYLKPDD (서열번호:567)
*LSWAADMWAVVTDWLASGLDKDYLKPDD (서열번호:568)
LSTAADLWAVVTDWLASGLDKDYLKPDD (서열번호:569)
*LSTAADLWAVVTDWLASGLDKDYLKPDD (서열번호:570)
LSWAADLWAVVTDWLASGLDKDYLKPDD (서열번호:571)
*LSWAADLWAVVTDWLASGLDKDYLKPDD (서열번호:572)
LSTAADVWAVVTDWLASGLDKDYLKPDD (서열번호:573)
*LSTAADVWAVVTDWLASGLDKDYLKPDD (서열번호:574)
LSWAADVWAVVTDWLASGLDKDYLKPDD (서열번호:575)
*LSWAADVWAVVTDWLASGLDKDYLKPDD (서열번호:576)
LSTAADMQGVVWDWLASGLDKDYLKPDD (서열번호:577)
*LSTAADMQGVVWDWLASGLDKDYLKPDD (서열번호:578)
LSWAADMQGVVWDWLASGLDKDYLKPDD (서열번호:579)
*LSWAADMQGVVWDWLASGLDKDYLKPDD (서열번호:580)
LSTAADLQGVVWDWLASGLDKDYLKPDD (서열번호:581)
*LSTAADLQGVVWDWLASGLDKDYLKPDD (서열번호:582)
LSWAADLQGVVWDWLASGLDKDYLKPDD (서열번호:583)
*LSWAADLQGVVWDWLASGLDKDYLKPDD (서열번호:584)
LSTAADVQGVVWDWLASGLDKDYLKPDD (서열번호:585)
*LSTAADVQGVVWDWLASGLDKDYLKPDD (서열번호:586)
LSWAADVQGVVWDWLASGLDKDYLKPDD (서열번호:587)
*LSWAADVQGVVWDWLASGLDKDYLKPDD (서열번호:588)
LSTAADMWGVVWDWLASGLDKDYLKPDD (서열번호:589)
*LSTAADMWGVVWDWLASGLDKDYLKPDD (서열번호:590)
LSWAADMWGVVWDWLASGLDKDYLKPDD (서열번호:591)
*LSWAADMWGVVWDWLASGLDKDYLKPDD (서열번호:592)
LSTAADLWGVVWDWLASGLDKDYLKPDD (서열번호:593)
*LSTAADLWGVVWDWLASGLDKDYLKPDD (서열번호:594)
LSWAADLWGVVWDWLASGLDKDYLKPDD (서열번호:595)
*LSWAADLWGVVWDWLASGLDKDYLKPDD (서열번호:596)
LSTAADVWGVVWDWLASGLDKDYLKPDD (서열번호:597)
*LSTAADVWGVVWDWLASGLDKDYLKPDD (서열번호:598)
LSWAADVWGVVWDWLASGLDKDYLKPDD (서열번호:599)
*LSWAADVWGVVWDWLASGLDKDYLKPDD (서열번호:600)
LSTAADMQAVVWDWLASGLDKDYLKPDD (서열번호:601)
*LSTAADMQAVVWDWLASGLDKDYLKPDD (서열번호:602)
LSWAADMQAVVWDWLASGLDKDYLKPDD (서열번호:603)
*LSWAADMQAVVWDWLASGLDKDYLKPDD (서열번호:604)
LSTAADLQAVVWDWLASGLDKDYLKPDD (서열번호:605)
*LSTAADLQAVVWDWLASGLDKDYLKPDD (서열번호:606)
LSWAADLQAVVWDWLASGLDKDYLKPDD (서열번호:607)
*LSWAADLQAVVWDWLASGLDKDYLKPDD (서열번호:608)
LSTAADVQAVVWDWLASGLDKDYLKPDD (서열번호:609)
*LSTAADVQAVVWDWLASGLDKDYLKPDD (서열번호:610)
LSWAADVQAVVWDWLASGLDKDYLKPDD (서열번호:611)
*LSWAADVQAVVWDWLASGLDKDYLKPDD (서열번호:612)
LSTAADMWAVVWDWLASGLDKDYLKPDD (서열번호:613)
*LSTAADMWAVVWDWLASGLDKDYLKPDD (서열번호:614)
LSWAADMWAVVWDWLASGLDKDYLKPDD (서열번호:615)
*LSWAADMWAVVWDWLASGLDKDYLKPDD (서열번호:616)
LSTAADLWAVVWDWLASGLDKDYLKPDD (서열번호:617)
*LSTAADLWAVVWDWLASGLDKDYLKPDD (서열번호:618)
LSWAADLWAVVWDWLASGLDKDYLKPDD (서열번호:619)
*LSWAADLWAVVWDWLASGLDKDYLKPDD (서열번호:620)
LSTAADVWAVVWDWLASGLDKDYLKPDD (서열번호:621)
*LSTAADVWAVVWDWLASGLDKDYLKPDD (서열번호:622)
LSWAADVWAVVWDWLASGLDKDYLKPDD (서열번호:623)
*LSWAADVWAVVWDWLASGLDKDYLKPDD (서열번호:624)
LSTAADMQGVVTDGVASGLDKDYLKPDD (서열번호:625)
*LSTAADMQGVVTDGVASGLDKDYLKPDD (서열번호:626)
LSWAADMQGVVTDGVASGLDKDYLKPDD (서열번호:627)
*LSWAADMQGVVTDGVASGLDKDYLKPDD (서열번호:628)
LSTAADLQGVVTDGVASGLDKDYLKPDD (서열번호:629)
*LSTAADLQGVVTDGVASGLDKDYLKPDD (서열번호:630)
LSWAADLQGVVTDGVASGLDKDYLKPDD (서열번호:631)
*LSWAADLQGVVTDGVASGLDKDYLKPDD (서열번호:632)
LSTAADVQGVVTDGVASGLDKDYLKPDD (서열번호:633)
*LSTAADVQGVVTDGVASGLDKDYLKPDD (서열번호:634)
LSWAADVQGVVTDGVASGLDKDYLKPDD (서열번호:635)
*LSWAADVQGVVTDGVASGLDKDYLKPDD (서열번호:636)
LSTAADMWGVVTDGVASGLDKDYLKPDD (서열번호:637)
*LSTAADMWGVVTDGVASGLDKDYLKPDD (서열번호:638)
LSWAADMWGVVTDGVASGLDKDYLKPDD (서열번호:639)
*LSWAADMWGVVTDGVASGLDKDYLKPDD (서열번호:640)
LSTAADLWGVVTDGVASGLDKDYLKPDD (서열번호:641)
*LSTAADLWGVVTDGVASGLDKDYLKPDD (서열번호:642)
LSWAADLWGVVTDGVASGLDKDYLKPDD (서열번호:643)
*LSWAADLWGVVTDGVASGLDKDYLKPDD (서열번호:644)
LSTAADVWGVVTDGVASGLDKDYLKPDD (서열번호:645)
*LSTAADVWGVVTDGVASGLDKDYLKPDD (서열번호:646)
LSWAADVWGVVTDGVASGLDKDYLKPDD (서열번호:647)
*LSWAADVWGVVTDGVASGLDKDYLKPDD (서열번호:648)
LSTAADMQAVVTDGVASGLDKDYLKPDD (서열번호:649)
*LSTAADMQAVVTDGVASGLDKDYLKPDD (서열번호:650)
LSWAADMQAVVTDGVASGLDKDYLKPDD (서열번호:651)
*LSWAADMQAVVTDGVASGLDKDYLKPDD (서열번호:652)
LSTAADLQAVVTDGVASGLDKDYLKPDD (서열번호:653)
*LSTAADLQAVVTDGVASGLDKDYLKPDD (서열번호:654)
LSWAADLQAVVTDGVASGLDKDYLKPDD (서열번호:655)
*LSWAADLQAVVTDGVASGLDKDYLKPDD (서열번호:656)
LSTAADVQAVVTDGVASGLDKDYLKPDD (서열번호:657)
*LSTAADVQAVVTDGVASGLDKDYLKPDD (서열번호:658)
LSWAADVQAVVTDGVASGLDKDYLKPDD (서열번호:659)
*LSWAADVQAVVTDGVASGLDKDYLKPDD (서열번호:660)
LSTAADMWAVVTDGVASGLDKDYLKPDD (서열번호:661)
*LSTAADMWAVVTDGVASGLDKDYLKPDD (서열번호:662)
LSWAADMWAVVTDGVASGLDKDYLKPDD (서열번호:663)
*LSWAADMWAVVTDGVASGLDKDYLKPDD (서열번호:664)
LSTAADLWAVVTDGVASGLDKDYLKPDD (서열번호:665)
*LSTAADLWAVVTDGVASGLDKDYLKPDD (서열번호:666)
LSWAADLWAVVTDGVASGLDKDYLKPDD (서열번호:667)
*LSWAADLWAVVTDGVASGLDKDYLKPDD (서열번호:668)
LSTAADVWAVVTDGVASGLDKDYLKPDD (서열번호:669)
*LSTAADVWAVVTDGVASGLDKDYLKPDD (서열번호:670)
LSWAADVWAVVTDGVASGLDKDYLKPDD (서열번호:671)
*LSWAADVWAVVTDGVASGLDKDYLKPDD (서열번호:672)
LSTAADMQGVVWDGVASGLDKDYLKPDD (서열번호:673)
*LSTAADMQGVVWDGVASGLDKDYLKPDD (서열번호:674)
LSWAADMQGVVWDGVASGLDKDYLKPDD (서열번호:675)
*LSWAADMQGVVWDGVASGLDKDYLKPDD (서열번호:676)
LSTAADLQGVVWDGVASGLDKDYLKPDD (서열번호:677)
*LSTAADLQGVVWDGVASGLDKDYLKPDD (서열번호:678)
LSWAADLQGVVWDGVASGLDKDYLKPDD (서열번호:679)
*LSWAADLQGVVWDGVASGLDKDYLKPDD (서열번호:680)
LSTAADVQGVVWDGVASGLDKDYLKPDD (서열번호:681)
*LSTAADVQGVVWDGVASGLDKDYLKPDD (서열번호:682)
LSWAADVQGVVWDGVASGLDKDYLKPDD (서열번호:683)
*LSWAADVQGVVWDGVASGLDKDYLKPDD (서열번호:684)
LSTAADMWGVVWDGVASGLDKDYLKPDD (서열번호:685)
*LSTAADMWGVVWDGVASGLDKDYLKPDD (서열번호:686)
LSWAADMWGVVWDGVASGLDKDYLKPDD (서열번호:687)
*LSWAADMWGVVWDGVASGLDKDYLKPDD (서열번호:688)
LSTAADLWGVVWDGVASGLDKDYLKPDD (서열번호:689)
*LSTAADLWGVVWDGVASGLDKDYLKPDD (서열번호:690)
LSWAADLWGVVWDGVASGLDKDYLKPDD (서열번호:691)
*LSWAADLWGVVWDGVASGLDKDYLKPDD (서열번호:692)
LSTAADVWGVVWDGVASGLDKDYLKPDD (서열번호:693)
*LSTAADVWGVVWDGVASGLDKDYLKPDD (서열번호:694)
LSWAADVWGVVWDGVASGLDKDYLKPDD (서열번호:695)
*LSWAADVWGVVWDGVASGLDKDYLKPDD (서열번호:696)
LSTAADMQAVVWDGVASGLDKDYLKPDD (서열번호:697)
*LSTAADMQAVVWDGVASGLDKDYLKPDD (서열번호:698)
LSWAADMQAVVWDGVASGLDKDYLKPDD (서열번호:699)
*LSWAADMQAVVWDGVASGLDKDYLKPDD (서열번호:700)
LSTAADLQAVVWDGVASGLDKDYLKPDD (서열번호:701)
*LSTAADLQAVVWDGVASGLDKDYLKPDD (서열번호:702)
LSWAADLQAVVWDGVASGLDKDYLKPDD (서열번호:703)
*LSWAADLQAVVWDGVASGLDKDYLKPDD (서열번호:704)
LSTAADVQAVVWDGVASGLDKDYLKPDD (서열번호:705)
*LSTAADVQAVVWDGVASGLDKDYLKPDD (서열번호:706)
LSWAADVQAVVWDGVASGLDKDYLKPDD (서열번호:707)
*LSWAADVQAVVWDGVASGLDKDYLKPDD (서열번호:708)
LSTAADMWAVVWDGVASGLDKDYLKPDD (서열번호:709)
*LSTAADMWAVVWDGVASGLDKDYLKPDD (서열번호:710)
LSWAADMWAVVWDGVASGLDKDYLKPDD (서열번호:711)
*LSWAADMWAVVWDGVASGLDKDYLKPDD (서열번호:712)
LSTAADLWAVVWDGVASGLDKDYLKPDD (서열번호:713)
*LSTAADLWAVVWDGVASGLDKDYLKPDD (서열번호:714)
LSWAADLWAVVWDGVASGLDKDYLKPDD (서열번호:715)
*LSWAADLWAVVWDGVASGLDKDYLKPDD (서열번호:716)
LSTAADVWAVVWDGVASGLDKDYLKPDD (서열번호:717)
*LSTAADVWAVVWDGVASGLDKDYLKPDD (서열번호:718)
LSWAADVWAVVWDGVASGLDKDYLKPDD (서열번호:719)
*LSWAADVWAVVWDGVASGLDKDYLKPDD (서열번호:720)
LSTAADMQGVVTDTVASGLDKDYLKPDD (서열번호:721)
*LSTAADMQGVVTDTVASGLDKDYLKPDD (서열번호:722)
LSWAADMQGVVTDTVASGLDKDYLKPDD (서열번호:723)
*LSWAADMQGVVTDTVASGLDKDYLKPDD (서열번호:724)
LSTAADLQGVVTDTVASGLDKDYLKPDD (서열번호:725)
*LSTAADLQGVVTDTVASGLDKDYLKPDD (서열번호:726)
LSWAADLQGVVTDTVASGLDKDYLKPDD (서열번호:727)
*LSWAADLQGVVTDTVASGLDKDYLKPDD (서열번호:728)
LSTAADVQGVVTDTVASGLDKDYLKPDD (서열번호:729)
*LSTAADVQGVVTDTVASGLDKDYLKPDD (서열번호:730)
LSWAADVQGVVTDTVASGLDKDYLKPDD (서열번호:731)
*LSWAADVQGVVTDTVASGLDKDYLKPDD (서열번호:732)
LSTAADMWGVVTDTVASGLDKDYLKPDD (서열번호:733)
*LSTAADMWGVVTDTVASGLDKDYLKPDD (서열번호:734)
LSWAADMWGVVTDTVASGLDKDYLKPDD (서열번호:735)
*LSWAADMWGVVTDTVASGLDKDYLKPDD (서열번호:736)
LSTAADLWGVVTDTVASGLDKDYLKPDD (서열번호:737)
*LSTAADLWGVVTDTVASGLDKDYLKPDD (서열번호:738)
LSWAADLWGVVTDTVASGLDKDYLKPDD (서열번호:739)
*LSWAADLWGVVTDTVASGLDKDYLKPDD (서열번호:740)
LSTAADVWGVVTDTVASGLDKDYLKPDD (서열번호:741)
*LSTAADVWGVVTDTVASGLDKDYLKPDD (서열번호:742)
LSWAADVWGVVTDTVASGLDKDYLKPDD (서열번호:743)
*LSWAADVWGVVTDTVASGLDKDYLKPDD (서열번호:744)
LSTAADMQAVVTDTVASGLDKDYLKPDD (서열번호:745)
*LSTAADMQAVVTDTVASGLDKDYLKPDD (서열번호:746)
LSWAADMQAVVTDTVASGLDKDYLKPDD (서열번호:747)
*LSWAADMQAVVTDTVASGLDKDYLKPDD (서열번호:748)
LSTAADLQAVVTDTVASGLDKDYLKPDD (서열번호:749)
*LSTAADLQAVVTDTVASGLDKDYLKPDD (서열번호:750)
LSWAADLQAVVTDTVASGLDKDYLKPDD (서열번호:751)
*LSWAADLQAVVTDTVASGLDKDYLKPDD (서열번호:752)
LSTAADVQAVVTDTVASGLDKDYLKPDD (서열번호:753)
*LSTAADVQAVVTDTVASGLDKDYLKPDD (서열번호:754)
LSWAADVQAVVTDTVASGLDKDYLKPDD (서열번호:755)
*LSWAADVQAVVTDTVASGLDKDYLKPDD (서열번호:756)
LSTAADMWAVVTDTVASGLDKDYLKPDD (서열번호:757)
*LSTAADMWAVVTDTVASGLDKDYLKPDD (서열번호:758)
LSWAADMWAVVTDTVASGLDKDYLKPDD (서열번호:759)
*LSWAADMWAVVTDTVASGLDKDYLKPDD (서열번호:760)
LSTAADLWAVVTDTVASGLDKDYLKPDD (서열번호:761)
*LSTAADLWAVVTDTVASGLDKDYLKPDD (서열번호:762)
LSWAADLWAVVTDTVASGLDKDYLKPDD (서열번호:763)
*LSWAADLWAVVTDTVASGLDKDYLKPDD (서열번호:764)
LSTAADVWAVVTDTVASGLDKDYLKPDD (서열번호:765)
*LSTAADVWAVVTDTVASGLDKDYLKPDD (서열번호:766)
LSWAADVWAVVTDTVASGLDKDYLKPDD (서열번호:767)
*LSWAADVWAVVTDTVASGLDKDYLKPDD (서열번호:768)
LSTAADMQGVVWDTVASGLDKDYLKPDD (서열번호:769)
*LSTAADMQGVVWDTVASGLDKDYLKPDD (서열번호:770)
LSWAADMQGVVWDTVASGLDKDYLKPDD (서열번호:771)
*LSWAADMQGVVWDTVASGLDKDYLKPDD (서열번호:772)
LSTAADLQGVVWDTVASGLDKDYLKPDD (서열번호:773)
*LSTAADLQGVVWDTVASGLDKDYLKPDD (서열번호:774)
LSWAADLQGVVWDTVASGLDKDYLKPDD (서열번호:775)
*LSWAADLQGVVWDTVASGLDKDYLKPDD (서열번호:776)
LSTAADVQGVVWDTVASGLDKDYLKPDD (서열번호:777)
*LSTAADVQGVVWDTVASGLDKDYLKPDD (서열번호:778)
LSWAADVQGVVWDTVASGLDKDYLKPDD (서열번호:779)
*LSWAADVQGVVWDTVASGLDKDYLKPDD (서열번호:780)
LSTAADMWGVVWDTVASGLDKDYLKPDD (서열번호:781)
*LSTAADMWGVVWDTVASGLDKDYLKPDD (서열번호:782)
LSWAADMWGVVWDTVASGLDKDYLKPDD (서열번호:783)
*LSWAADMWGVVWDTVASGLDKDYLKPDD (서열번호:784)
LSTAADLWGVVWDTVASGLDKDYLKPDD (서열번호:785)
*LSTAADLWGVVWDTVASGLDKDYLKPDD (서열번호:786)
LSWAADLWGVVWDTVASGLDKDYLKPDD (서열번호:787)
*LSWAADLWGVVWDTVASGLDKDYLKPDD (서열번호:788)
LSTAADVWGVVWDTVASGLDKDYLKPDD (서열번호:789)
*LSTAADVWGVVWDTVASGLDKDYLKPDD (서열번호:790)
LSWAADVWGVVWDTVASGLDKDYLKPDD (서열번호:791)
*LSWAADVWGVVWDTVASGLDKDYLKPDD (서열번호:792)
LSTAADMQAVVWDTVASGLDKDYLKPDD (서열번호:793)
*LSTAADMQAVVWDTVASGLDKDYLKPDD (서열번호:794)
LSWAADMQAVVWDTVASGLDKDYLKPDD (서열번호:795)
*LSWAADMQAVVWDTVASGLDKDYLKPDD (서열번호:796)
LSTAADLQAVVWDTVASGLDKDYLKPDD (서열번호:797)
*LSTAADLQAVVWDTVASGLDKDYLKPDD (서열번호:798)
LSWAADLQAVVWDTVASGLDKDYLKPDD (서열번호:799)
*LSWAADLQAVVWDTVASGLDKDYLKPDD (서열번호:800)
LSTAADVQAVVWDTVASGLDKDYLKPDD (서열번호:801)
*LSTAADVQAVVWDTVASGLDKDYLKPDD (서열번호:802)
LSWAADVQAVVWDTVASGLDKDYLKPDD (서열번호:803)
*LSWAADVQAVVWDTVASGLDKDYLKPDD (서열번호:804)
LSTAADMWAVVWDTVASGLDKDYLKPDD (서열번호:805)
*LSTAADMWAVVWDTVASGLDKDYLKPDD (서열번호:806)
LSWAADMWAVVWDTVASGLDKDYLKPDD (서열번호:807)
*LSWAADMWAVVWDTVASGLDKDYLKPDD (서열번호:808)
LSTAADLWAVVWDTVASGLDKDYLKPDD (서열번호:809)
*LSTAADLWAVVWDTVASGLDKDYLKPDD (서열번호:810)
LSWAADLWAVVWDTVASGLDKDYLKPDD (서열번호:811)
*LSWAADLWAVVWDTVASGLDKDYLKPDD (서열번호:812)
LSTAADVWAVVWDTVASGLDKDYLKPDD (서열번호:813)
*LSTAADVWAVVWDTVASGLDKDYLKPDD (서열번호:814)
LSWAADVWAVVWDTVASGLDKDYLKPDD (서열번호:815)
*LSWAADVWAVVWDTVASGLDKDYLKPDD (서열번호:816)
LSTAADMQGVVTDWVASGLDKDYLKPDD (서열번호:817)
*LSTAADMQGVVTDWVASGLDKDYLKPDD (서열번호:818)
LSWAADMQGVVTDWVASGLDKDYLKPDD (서열번호:819)
*LSWAADMQGVVTDWVASGLDKDYLKPDD (서열번호:820)
LSTAADLQGVVTDWVASGLDKDYLKPDD (서열번호:821)
*LSTAADLQGVVTDWVASGLDKDYLKPDD (서열번호:822)
LSWAADLQGVVTDWVASGLDKDYLKPDD (서열번호:823)
*LSWAADLQGVVTDWVASGLDKDYLKPDD (서열번호:824)
LSTAADVQGVVTDWVASGLDKDYLKPDD (서열번호:825)
*LSTAADVQGVVTDWVASGLDKDYLKPDD (서열번호:826)
LSWAADVQGVVTDWVASGLDKDYLKPDD (서열번호:827)
*LSWAADVQGVVTDWVASGLDKDYLKPDD (서열번호:828)
LSTAADMWGVVTDWVASGLDKDYLKPDD (서열번호:829)
*LSTAADMWGVVTDWVASGLDKDYLKPDD (서열번호:830)
LSWAADMWGVVTDWVASGLDKDYLKPDD (서열번호:831)
*LSWAADMWGVVTDWVASGLDKDYLKPDD (서열번호:832)
LSTAADLWGVVTDWVASGLDKDYLKPDD (서열번호:833)
*LSTAADLWGVVTDWVASGLDKDYLKPDD (서열번호:834)
LSWAADLWGVVTDWVASGLDKDYLKPDD (서열번호:835)
*LSWAADLWGVVTDWVASGLDKDYLKPDD (서열번호:836)
LSTAADVWGVVTDWVASGLDKDYLKPDD (서열번호:837)
*LSTAADVWGVVTDWVASGLDKDYLKPDD (서열번호:838)
LSWAADVWGVVTDWVASGLDKDYLKPDD (서열번호:839)
*LSWAADVWGVVTDWVASGLDKDYLKPDD (서열번호:840)
LSTAADMQAVVTDWVASGLDKDYLKPDD (서열번호:841)
*LSTAADMQAVVTDWVASGLDKDYLKPDD (서열번호:842)
LSWAADMQAVVTDWVASGLDKDYLKPDD (서열번호:843)
*LSWAADMQAVVTDWVASGLDKDYLKPDD (서열번호:844)
LSTAADLQAVVTDWVASGLDKDYLKPDD (서열번호:845)
*LSTAADLQAVVTDWVASGLDKDYLKPDD (서열번호:846)
LSWAADLQAVVTDWVASGLDKDYLKPDD (서열번호:847)
*LSWAADLQAVVTDWVASGLDKDYLKPDD (서열번호:848)
LSTAADVQAVVTDWVASGLDKDYLKPDD (서열번호:849)
*LSTAADVQAVVTDWVASGLDKDYLKPDD (서열번호:850)
LSWAADVQAVVTDWVASGLDKDYLKPDD (서열번호:851)
*LSWAADVQAVVTDWVASGLDKDYLKPDD (서열번호:852)
LSTAADMWAVVTDWVASGLDKDYLKPDD (서열번호:853)
*LSTAADMWAVVTDWVASGLDKDYLKPDD (서열번호:854)
LSWAADMWAVVTDWVASGLDKDYLKPDD (서열번호:855)
*LSWAADMWAVVTDWVASGLDKDYLKPDD (서열번호:856)
LSTAADLWAVVTDWVASGLDKDYLKPDD (서열번호:857)
*LSTAADLWAVVTDWVASGLDKDYLKPDD (서열번호:858)
LSWAADLWAVVTDWVASGLDKDYLKPDD (서열번호:859)
*LSWAADLWAVVTDWVASGLDKDYLKPDD (서열번호:860)
LSTAADVWAVVTDWVASGLDKDYLKPDD (서열번호:861)
*LSTAADVWAVVTDWVASGLDKDYLKPDD (서열번호:862)
LSWAADVWAVVTDWVASGLDKDYLKPDD (서열번호:863)
*LSWAADVWAVVTDWVASGLDKDYLKPDD (서열번호:864)
LSTAADMQGVVWDWVASGLDKDYLKPDD (서열번호:865)
*LSTAADMQGVVWDWVASGLDKDYLKPDD (서열번호:866)
LSWAADMQGVVWDWVASGLDKDYLKPDD (서열번호:867)
*LSWAADMQGVVWDWVASGLDKDYLKPDD (서열번호:868)
LSTAADLQGVVWDWVASGLDKDYLKPDD (서열번호:869)
*LSTAADLQGVVWDWVASGLDKDYLKPDD (서열번호:870)
LSWAADLQGVVWDWVASGLDKDYLKPDD (서열번호:871)
*LSWAADLQGVVWDWVASGLDKDYLKPDD (서열번호:872)
LSTAADVQGVVWDWVASGLDKDYLKPDD (서열번호:873)
*LSTAADVQGVVWDWVASGLDKDYLKPDD (서열번호:874)
LSWAADVQGVVWDWVASGLDKDYLKPDD (서열번호:875)
*LSWAADVQGVVWDWVASGLDKDYLKPDD (서열번호:876)
LSTAADMWGVVWDWVASGLDKDYLKPDD (서열번호:877)
*LSTAADMWGVVWDWVASGLDKDYLKPDD (서열번호:878)
LSWAADMWGVVWDWVASGLDKDYLKPDD (서열번호:879)
*LSWAADMWGVVWDWVASGLDKDYLKPDD (서열번호:880)
LSTAADLWGVVWDWVASGLDKDYLKPDD (서열번호:881)
*LSTAADLWGVVWDWVASGLDKDYLKPDD (서열번호:882)
LSWAADLWGVVWDWVASGLDKDYLKPDD (서열번호:883)
*LSWAADLWGVVWDWVASGLDKDYLKPDD (서열번호:884)
LSTAADVWGVVWDWVASGLDKDYLKPDD (서열번호:885)
*LSTAADVWGVVWDWVASGLDKDYLKPDD (서열번호:886)
LSWAADVWGVVWDWVASGLDKDYLKPDD (서열번호:887)
*LSWAADVWGVVWDWVASGLDKDYLKPDD (서열번호:888)
LSTAADMQAVVWDWVASGLDKDYLKPDD (서열번호:889)
*LSTAADMQAVVWDWVASGLDKDYLKPDD (서열번호:890)
LSWAADMQAVVWDWVASGLDKDYLKPDD (서열번호:891)
*LSWAADMQAVVWDWVASGLDKDYLKPDD (서열번호:892)
LSTAADLQAVVWDWVASGLDKDYLKPDD (서열번호:893)
*LSTAADLQAVVWDWVASGLDKDYLKPDD (서열번호:894)
LSWAADLQAVVWDWVASGLDKDYLKPDD (서열번호:895)
*LSWAADLQAVVWDWVASGLDKDYLKPDD (서열번호:896)
LSTAADVQAVVWDWVASGLDKDYLKPDD (서열번호:897)
*LSTAADVQAVVWDWVASGLDKDYLKPDD (서열번호:898)
LSWAADVQAVVWDWVASGLDKDYLKPDD (서열번호:899)
*LSWAADVQAVVWDWVASGLDKDYLKPDD (서열번호:900)
LSTAADMWAVVWDWVASGLDKDYLKPDD (서열번호:901)
*LSTAADMWAVVWDWVASGLDKDYLKPDD (서열번호:902)
LSWAADMWAVVWDWVASGLDKDYLKPDD (서열번호:903)
*LSWAADMWAVVWDWVASGLDKDYLKPDD (서열번호:904)
LSTAADLWAVVWDWVASGLDKDYLKPDD (서열번호:905)
*LSTAADLWAVVWDWVASGLDKDYLKPDD (서열번호:906)
LSWAADLWAVVWDWVASGLDKDYLKPDD (서열번호:907)
*LSWAADLWAVVWDWVASGLDKDYLKPDD (서열번호:908)
LSTAADVWAVVWDWVASGLDKDYLKPDD (서열번호:909)
*LSTAADVWAVVWDWVASGLDKDYLKPDD (서열번호:910)
LSWAADVWAVVWDWVASGLDKDYLKPDD (서열번호:911)
*LSWAADVWAVVWDWVASGLDKDYLKPDD (서열번호:912)
LSTAADMQGVVTDGMASGLDKDYLKPDD$ (서열번호:913)
*LSTAADMQGVVTDGMASGLDKDYLKPDD$ (서열번호:914)
LSWAADMQGVVTDGMASGLDKDYLKPDD$ (서열번호:915)
*LSWAADMQGVVTDGMASGLDKDYLKPDD$ (서열번호:916)
LSTAADLQGVVTDGMASGLDKDYLKPDD$ (서열번호:917)
*LSTAADLQGVVTDGMASGLDKDYLKPDD$ (서열번호:918)
LSWAADLQGVVTDGMASGLDKDYLKPDD$ (서열번호:919)
*LSWAADLQGVVTDGMASGLDKDYLKPDD$ (서열번호:920)
LSTAADVQGVVTDGMASGLDKDYLKPDD$ (서열번호:921)
*LSTAADVQGVVTDGMASGLDKDYLKPDD$ (서열번호:922)
LSWAADVQGVVTDGMASGLDKDYLKPDD$ (서열번호:923)
*LSWAADVQGVVTDGMASGLDKDYLKPDD$ (서열번호:924)
LSTAADMWGVVTDGMASGLDKDYLKPDD$ (서열번호:925)
*LSTAADMWGVVTDGMASGLDKDYLKPDD$ (서열번호:926)
LSWAADMWGVVTDGMASGLDKDYLKPDD$ (서열번호:927)
*LSWAADMWGVVTDGMASGLDKDYLKPDD$ (서열번호:928)
LSTAADLWGVVTDGMASGLDKDYLKPDD$ (서열번호:929)
*LSTAADLWGVVTDGMASGLDKDYLKPDD$ (서열번호:930)
LSWAADLWGVVTDGMASGLDKDYLKPDD$ (서열번호:931)
*LSWAADLWGVVTDGMASGLDKDYLKPDD$ (서열번호:932)
LSTAADVWGVVTDGMASGLDKDYLKPDD$ (서열번호:933)
*LSTAADVWGVVTDGMASGLDKDYLKPDD$ (서열번호:934)
LSWAADVWGVVTDGMASGLDKDYLKPDD$ (서열번호:935)
*LSWAADVWGVVTDGMASGLDKDYLKPDD$ (서열번호:936)
LSTAADMQAVVTDGMASGLDKDYLKPDD$ (서열번호:937)
*LSTAADMQAVVTDGMASGLDKDYLKPDD$ (서열번호:938)
LSWAADMQAVVTDGMASGLDKDYLKPDD$ (서열번호:939)
*LSWAADMQAVVTDGMASGLDKDYLKPDD$ (서열번호:940)
LSTAADLQAVVTDGMASGLDKDYLKPDD$ (서열번호:941)
*LSTAADLQAVVTDGMASGLDKDYLKPDD$ (서열번호:942)
LSWAADLQAVVTDGMASGLDKDYLKPDD$ (서열번호:943)
*LSWAADLQAVVTDGMASGLDKDYLKPDD$ (서열번호:944)
LSTAADVQAVVTDGMASGLDKDYLKPDD$ (서열번호:945)
*LSTAADVQAVVTDGMASGLDKDYLKPDD$ (서열번호:946)
LSWAADVQAVVTDGMASGLDKDYLKPDD$ (서열번호:947)
*LSWAADVQAVVTDGMASGLDKDYLKPDD$ (서열번호:948)
LSTAADMWAVVTDGMASGLDKDYLKPDD$ (서열번호:949)
*LSTAADMWAVVTDGMASGLDKDYLKPDD$ (서열번호:950)
LSWAADMWAVVTDGMASGLDKDYLKPDD$ (서열번호:951)
*LSWAADMWAVVTDGMASGLDKDYLKPDD$ (서열번호:952)
LSTAADLWAVVTDGMASGLDKDYLKPDD$ (서열번호:953)
*LSTAADLWAVVTDGMASGLDKDYLKPDD$ (서열번호:954)
LSWAADLWAVVTDGMASGLDKDYLKPDD$ (서열번호:955)
*LSWAADLWAVVTDGMASGLDKDYLKPDD$ (서열번호:956)
LSTAADVWAVVTDGMASGLDKDYLKPDD$ (서열번호:957)
*LSTAADVWAVVTDGMASGLDKDYLKPDD$ (서열번호:958)
LSWAADVWAVVTDGMASGLDKDYLKPDD$ (서열번호:959)
*LSWAADVWAVVTDGMASGLDKDYLKPDD$ (서열번호:960)
LSTAADMQGVVWDGMASGLDKDYLKPDD$ (서열번호:961)
*LSTAADMQGVVWDGMASGLDKDYLKPDD$ (서열번호:962)
LSWAADMQGVVWDGMASGLDKDYLKPDD$ (서열번호:963)
*LSWAADMQGVVWDGMASGLDKDYLKPDD$ (서열번호:964)
LSTAADLQGVVWDGMASGLDKDYLKPDD$ (서열번호:965)
*LSTAADLQGVVWDGMASGLDKDYLKPDD$ (서열번호:966)
LSWAADLQGVVWDGMASGLDKDYLKPDD$ (서열번호:967)
*LSWAADLQGVVWDGMASGLDKDYLKPDD$ (서열번호:968)
LSTAADVQGVVWDGMASGLDKDYLKPDD$ (서열번호:969)
*LSTAADVQGVVWDGMASGLDKDYLKPDD$ (서열번호:970)
LSWAADVQGVVWDGMASGLDKDYLKPDD$ (서열번호:971)
*LSWAADVQGVVWDGMASGLDKDYLKPDD$ (서열번호:972)
LSTAADMWGVVWDGMASGLDKDYLKPDD$ (서열번호:973)
*LSTAADMWGVVWDGMASGLDKDYLKPDD$ (서열번호:974)
LSWAADMWGVVWDGMASGLDKDYLKPDD$ (서열번호:975)
*LSWAADMWGVVWDGMASGLDKDYLKPDD$ (서열번호:976)
LSTAADLWGVVWDGMASGLDKDYLKPDD$ (서열번호:977)
*LSTAADLWGVVWDGMASGLDKDYLKPDD$ (서열번호:978)
LSWAADLWGVVWDGMASGLDKDYLKPDD$ (서열번호:979)
*LSWAADLWGVVWDGMASGLDKDYLKPDD$ (서열번호:980)
LSTAADVWGVVWDGMASGLDKDYLKPDD$ (서열번호:981)
*LSTAADVWGVVWDGMASGLDKDYLKPDD$ (서열번호:982)
LSWAADVWGVVWDGMASGLDKDYLKPDD$ (서열번호:983)
*LSWAADVWGVVWDGMASGLDKDYLKPDD$ (서열번호:984)
LSTAADMQAVVWDGMASGLDKDYLKPDD$ (서열번호:985)
*LSTAADMQAVVWDGMASGLDKDYLKPDD$ (서열번호:986)
LSWAADMQAVVWDGMASGLDKDYLKPDD$ (서열번호:987)
*LSWAADMQAVVWDGMASGLDKDYLKPDD$ (서열번호:988)
LSTAADLQAVVWDGMASGLDKDYLKPDD$ (서열번호:989)
*LSTAADLQAVVWDGMASGLDKDYLKPDD$ (서열번호:990)
LSWAADLQAVVWDGMASGLDKDYLKPDD$ (서열번호:991)
*LSWAADLQAVVWDGMASGLDKDYLKPDD$ (서열번호:992)
LSTAADVQAVVWDGMASGLDKDYLKPDD$ (서열번호:993)
*LSTAADVQAVVWDGMASGLDKDYLKPDD$ (서열번호:994)
LSWAADVQAVVWDGMASGLDKDYLKPDD$ (서열번호:995)
*LSWAADVQAVVWDGMASGLDKDYLKPDD$ (서열번호:996)
LSTAADMWAVVWDGMASGLDKDYLKPDD$ (서열번호:997)
*LSTAADMWAVVWDGMASGLDKDYLKPDD$ (서열번호:998)
LSWAADMWAVVWDGMASGLDKDYLKPDD$ (서열번호:999)
*LSWAADMWAVVWDGMASGLDKDYLKPDD$ (서열번호:1000)
LSTAADLWAVVWDGMASGLDKDYLKPDD$ (서열번호:1001)
*LSTAADLWAVVWDGMASGLDKDYLKPDD$ (서열번호:1002)
LSWAADLWAVVWDGMASGLDKDYLKPDD$ (서열번호:1003)
*LSWAADLWAVVWDGMASGLDKDYLKPDD$ (서열번호:1004)
LSTAADVWAVVWDGMASGLDKDYLKPDD$ (서열번호:1005)
*LSTAADVWAVVWDGMASGLDKDYLKPDD$ (서열번호:1006)
LSWAADVWAVVWDGMASGLDKDYLKPDD$ (서열번호:1007)
*LSWAADVWAVVWDGMASGLDKDYLKPDD$ (서열번호:1008)
LSTAADMQGVVTDTMASGLDKDYLKPDD$ (서열번호:1009)
*LSTAADMQGVVTDTMASGLDKDYLKPDD$ (서열번호:1010)
LSWAADMQGVVTDTMASGLDKDYLKPDD$ (서열번호:1011)
*LSWAADMQGVVTDTMASGLDKDYLKPDD$ (서열번호:1012)
LSTAADLQGVVTDTMASGLDKDYLKPDD$ (서열번호:1013)
*LSTAADLQGVVTDTMASGLDKDYLKPDD$ (서열번호:1014)
LSWAADLQGVVTDTMASGLDKDYLKPDD$ (서열번호:1015)
*LSWAADLQGVVTDTMASGLDKDYLKPDD$ (서열번호:1016)
LSTAADVQGVVTDTMASGLDKDYLKPDD$ (서열번호:1017)
*LSTAADVQGVVTDTMASGLDKDYLKPDD$ (서열번호:1018)
LSWAADVQGVVTDTMASGLDKDYLKPDD$ (서열번호:1019)
*LSWAADVQGVVTDTMASGLDKDYLKPDD$ (서열번호:1020)
LSTAADMWGVVTDTMASGLDKDYLKPDD$ (서열번호:1021)
*LSTAADMWGVVTDTMASGLDKDYLKPDD$ (서열번호:1022)
LSWAADMWGVVTDTMASGLDKDYLKPDD$ (서열번호:1023)
*LSWAADMWGVVTDTMASGLDKDYLKPDD$ (서열번호:1024)
LSTAADLWGVVTDTMASGLDKDYLKPDD$ (서열번호:1025)
*LSTAADLWGVVTDTMASGLDKDYLKPDD$ (서열번호:1026)
LSWAADLWGVVTDTMASGLDKDYLKPDD$ (서열번호:1027)
*LSWAADLWGVVTDTMASGLDKDYLKPDD$ (서열번호:1028)
LSTAADVWGVVTDTMASGLDKDYLKPDD$ (서열번호:1029)
*LSTAADVWGVVTDTMASGLDKDYLKPDD$ (서열번호:1030)
LSWAADVWGVVTDTMASGLDKDYLKPDD$ (서열번호:1031)
*LSWAADVWGVVTDTMASGLDKDYLKPDD$ (서열번호:1032)
LSTAADMQAVVTDTMASGLDKDYLKPDD$ (서열번호:1033)
*LSTAADMQAVVTDTMASGLDKDYLKPDD$ (서열번호:1034)
LSWAADMQAVVTDTMASGLDKDYLKPDD$ (서열번호:1035)
*LSWAADMQAVVTDTMASGLDKDYLKPDD$ (서열번호:1036)
LSTAADLQAVVTDTMASGLDKDYLKPDD$ (서열번호:1037)
*LSTAADLQAVVTDTMASGLDKDYLKPDD$ (서열번호:1038)
LSWAADLQAVVTDTMASGLDKDYLKPDD$ (서열번호:1039)
*LSWAADLQAVVTDTMASGLDKDYLKPDD$ (서열번호:1040)
LSTAADVQAVVTDTMASGLDKDYLKPDD$ (서열번호:1041)
*LSTAADVQAVVTDTMASGLDKDYLKPDD$ (서열번호:1042)
LSWAADVQAVVTDTMASGLDKDYLKPDD$ (서열번호:1043)
*LSWAADVQAVVTDTMASGLDKDYLKPDD$ (서열번호:1044)
LSTAADMWAVVTDTMASGLDKDYLKPDD$ (서열번호:1045)
*LSTAADMWAVVTDTMASGLDKDYLKPDD$ (서열번호:1046)
LSWAADMWAVVTDTMASGLDKDYLKPDD$ (서열번호:1047)
*LSWAADMWAVVTDTMASGLDKDYLKPDD$ (서열번호:1048)
LSTAADLWAVVTDTMASGLDKDYLKPDD$ (서열번호:1049)
*LSTAADLWAVVTDTMASGLDKDYLKPDD$ (서열번호:1050)
LSWAADLWAVVTDTMASGLDKDYLKPDD$ (서열번호:1051)
*LSWAADLWAVVTDTMASGLDKDYLKPDD$ (서열번호:1052)
LSTAADVWAVVTDTMASGLDKDYLKPDD$ (서열번호:1053)
*LSTAADVWAVVTDTMASGLDKDYLKPDD$ (서열번호:1054)
LSWAADVWAVVTDTMASGLDKDYLKPDD$ (서열번호:1055)
*LSWAADVWAVVTDTMASGLDKDYLKPDD$ (서열번호:1056)
LSTAADMQGVVWDTMASGLDKDYLKPDD$ (서열번호:1057)
*LSTAADMQGVVWDTMASGLDKDYLKPDD$ (서열번호:1058)
LSWAADMQGVVWDTMASGLDKDYLKPDD$ (서열번호:1059)
*LSWAADMQGVVWDTMASGLDKDYLKPDD$ (서열번호:1060)
LSTAADLQGVVWDTMASGLDKDYLKPDD$ (서열번호:1061)
*LSTAADLQGVVWDTMASGLDKDYLKPDD$ (서열번호:1062)
LSWAADLQGVVWDTMASGLDKDYLKPDD$ (서열번호:1063)
*LSWAADLQGVVWDTMASGLDKDYLKPDD$ (서열번호:1064)
LSTAADVQGVVWDTMASGLDKDYLKPDD$ (서열번호:1065)
*LSTAADVQGVVWDTMASGLDKDYLKPDD$ (서열번호:1066)
LSWAADVQGVVWDTMASGLDKDYLKPDD$ (서열번호:1067)
*LSWAADVQGVVWDTMASGLDKDYLKPDD$ (서열번호:1068)
LSTAADMWGVVWDTMASGLDKDYLKPDD$ (서열번호:1069)
*LSTAADMWGVVWDTMASGLDKDYLKPDD$ (서열번호:1070)
LSWAADMWGVVWDTMASGLDKDYLKPDD$ (서열번호:1071)
*LSWAADMWGVVWDTMASGLDKDYLKPDD$ (서열번호:1072)
LSTAADLWGVVWDTMASGLDKDYLKPDD$ (서열번호:1073)
*LSTAADLWGVVWDTMASGLDKDYLKPDD$ (서열번호:1074)
LSWAADLWGVVWDTMASGLDKDYLKPDD$ (서열번호:1075)
*LSWAADLWGVVWDTMASGLDKDYLKPDD$ (서열번호:1076)
LSTAADVWGVVWDTMASGLDKDYLKPDD$ (서열번호:1077)
*LSTAADVWGVVWDTMASGLDKDYLKPDD$ (서열번호:1078)
LSWAADVWGVVWDTMASGLDKDYLKPDD$ (서열번호:1079)
*LSWAADVWGVVWDTMASGLDKDYLKPDD$ (서열번호:1080)
LSTAADMQAVVWDTMASGLDKDYLKPDD$ (서열번호:1081)
*LSTAADMQAVVWDTMASGLDKDYLKPDD$ (서열번호:1082)
LSWAADMQAVVWDTMASGLDKDYLKPDD$ (서열번호:1083)
*LSWAADMQAVVWDTMASGLDKDYLKPDD$ (서열번호:1084)
LSTAADLQAVVWDTMASGLDKDYLKPDD$ (서열번호:1085)
*LSTAADLQAVVWDTMASGLDKDYLKPDD$ (서열번호:1086)
LSWAADLQAVVWDTMASGLDKDYLKPDD$ (서열번호:1087)
*LSWAADLQAVVWDTMASGLDKDYLKPDD$ (서열번호:1088)
LSTAADVQAVVWDTMASGLDKDYLKPDD$ (서열번호:1089)
*LSTAADVQAVVWDTMASGLDKDYLKPDD$ (서열번호:1090)
LSWAADVQAVVWDTMASGLDKDYLKPDD$ (서열번호:1091)
*LSWAADVQAVVWDTMASGLDKDYLKPDD$ (서열번호:1092)
LSTAADMWAVVWDTMASGLDKDYLKPDD$ (서열번호:1093)
*LSTAADMWAVVWDTMASGLDKDYLKPDD$ (서열번호:1094)
LSWAADMWAVVWDTMASGLDKDYLKPDD$ (서열번호:1095)
*LSWAADMWAVVWDTMASGLDKDYLKPDD$ (서열번호:1096)
LSTAADLWAVVWDTMASGLDKDYLKPDD$ (서열번호:1097)
*LSTAADLWAVVWDTMASGLDKDYLKPDD$ (서열번호:1098)
LSWAADLWAVVWDTMASGLDKDYLKPDD$ (서열번호:1099)
*LSWAADLWAVVWDTMASGLDKDYLKPDD$ (서열번호:1100)
LSTAADVWAVVWDTMASGLDKDYLKPDD$ (서열번호:1101)
*LSTAADVWAVVWDTMASGLDKDYLKPDD$ (서열번호:1102)
LSWAADVWAVVWDTMASGLDKDYLKPDD$ (서열번호:1103)
*LSWAADVWAVVWDTMASGLDKDYLKPDD$ (서열번호:1104)
LSTAADMQGVVTDWMASGLDKDYLKPDD$ (서열번호:1105)
*LSTAADMQGVVTDWMASGLDKDYLKPDD$ (서열번호:1106)
LSWAADMQGVVTDWMASGLDKDYLKPDD$ (서열번호:1107)
*LSWAADMQGVVTDWMASGLDKDYLKPDD$ (서열번호:1108)
LSTAADLQGVVTDWMASGLDKDYLKPDD$ (서열번호:1109)
*LSTAADLQGVVTDWMASGLDKDYLKPDD$ (서열번호:1110)
LSWAADLQGVVTDWMASGLDKDYLKPDD$ (서열번호:1111)
*LSWAADLQGVVTDWMASGLDKDYLKPDD$ (서열번호:1112)
LSTAADVQGVVTDWMASGLDKDYLKPDD$ (서열번호:1113)
*LSTAADVQGVVTDWMASGLDKDYLKPDD$ (서열번호:1114)
LSWAADVQGVVTDWMASGLDKDYLKPDD$ (서열번호:1115)
*LSWAADVQGVVTDWMASGLDKDYLKPDD$ (서열번호:1116)
LSTAADMWGVVTDWMASGLDKDYLKPDD$ (서열번호:1117)
*LSTAADMWGVVTDWMASGLDKDYLKPDD$ (서열번호:1118)
LSWAADMWGVVTDWMASGLDKDYLKPDD$ (서열번호:1119)
*LSWAADMWGVVTDWMASGLDKDYLKPDD$ (서열번호:1120)
LSTAADLWGVVTDWMASGLDKDYLKPDD$ (서열번호:1121)
*LSTAADLWGVVTDWMASGLDKDYLKPDD$ (서열번호:1122)
LSWAADLWGVVTDWMASGLDKDYLKPDD$ (서열번호:1123)
*LSWAADLWGVVTDWMASGLDKDYLKPDD$ (서열번호:1124)
LSTAADVWGVVTDWMASGLDKDYLKPDD$ (서열번호:1125)
*LSTAADVWGVVTDWMASGLDKDYLKPDD$ (서열번호:1126)
LSWAADVWGVVTDWMASGLDKDYLKPDD$ (서열번호:1127)
*LSWAADVWGVVTDWMASGLDKDYLKPDD$ (서열번호:1128)
LSTAADMQAVVTDWMASGLDKDYLKPDD$ (서열번호:1129)
*LSTAADMQAVVTDWMASGLDKDYLKPDD$ (서열번호:1130)
LSWAADMQAVVTDWMASGLDKDYLKPDD$ (서열번호:1131)
*LSWAADMQAVVTDWMASGLDKDYLKPDD$ (서열번호:1132)
LSTAADLQAVVTDWMASGLDKDYLKPDD$ (서열번호:1133)
*LSTAADLQAVVTDWMASGLDKDYLKPDD$ (서열번호:1134)
LSWAADLQAVVTDWMASGLDKDYLKPDD$ (서열번호:1135)
*LSWAADLQAVVTDWMASGLDKDYLKPDD$ (서열번호:1136)
LSTAADVQAVVTDWMASGLDKDYLKPDD$ (서열번호:1137)
*LSTAADVQAVVTDWMASGLDKDYLKPDD$ (서열번호:1138)
LSWAADVQAVVTDWMASGLDKDYLKPDD$ (서열번호:1139)
*LSWAADVQAVVTDWMASGLDKDYLKPDD$ (서열번호:1140)
LSTAADMWAVVTDWMASGLDKDYLKPDD$ (서열번호:1141)
*LSTAADMWAVVTDWMASGLDKDYLKPDD$ (서열번호:1142)
LSWAADMWAVVTDWMASGLDKDYLKPDD$ (서열번호:1143)
*LSWAADMWAVVTDWMASGLDKDYLKPDD$ (서열번호:1144)
LSTAADLWAVVTDWMASGLDKDYLKPDD$ (서열번호:1145)
*LSTAADLWAVVTDWMASGLDKDYLKPDD$ (서열번호:1146)
LSWAADLWAVVTDWMASGLDKDYLKPDD$ (서열번호:1147)
*LSWAADLWAVVTDWMASGLDKDYLKPDD$ (서열번호:1148)
LSTAADVWAVVTDWMASGLDKDYLKPDD$ (서열번호:1149)
*LSTAADVWAVVTDWMASGLDKDYLKPDD$ (서열번호:1150)
LSWAADVWAVVTDWMASGLDKDYLKPDD$ (서열번호:1151)
*LSWAADVWAVVTDWMASGLDKDYLKPDD$ (서열번호:1152)
LSTAADMQGVVWDWMASGLDKDYLKPDD$ (서열번호:1153)
*LSTAADMQGVVWDWMASGLDKDYLKPDD$ (서열번호:1154)
LSWAADMQGVVWDWMASGLDKDYLKPDD$ (서열번호:1155)
*LSWAADMQGVVWDWMASGLDKDYLKPDD$ (서열번호:1156)
LSTAADLQGVVWDWMASGLDKDYLKPDD$ (서열번호:1157)
*LSTAADLQGVVWDWMASGLDKDYLKPDD$ (서열번호:1158)
LSWAADLQGVVWDWMASGLDKDYLKPDD$ (서열번호:1159)
*LSWAADLQGVVWDWMASGLDKDYLKPDD$ (서열번호:1160)
LSTAADVQGVVWDWMASGLDKDYLKPDD$ (서열번호:1161)
*LSTAADVQGVVWDWMASGLDKDYLKPDD$ (서열번호:1162)
LSWAADVQGVVWDWMASGLDKDYLKPDD$ (서열번호:1163)
*LSWAADVQGVVWDWMASGLDKDYLKPDD$ (서열번호:1164)
LSTAADMWGVVWDWMASGLDKDYLKPDD$ (서열번호:1165)
*LSTAADMWGVVWDWMASGLDKDYLKPDD$ (서열번호:1166)
LSWAADMWGVVWDWMASGLDKDYLKPDD$ (서열번호:1167)
*LSWAADMWGVVWDWMASGLDKDYLKPDD$ (서열번호:1168)
LSTAADLWGVVWDWMASGLDKDYLKPDD$ (서열번호:1169)
*LSTAADLWGVVWDWMASGLDKDYLKPDD$ (서열번호:1170)
LSWAADLWGVVWDWMASGLDKDYLKPDD$ (서열번호:1171)
*LSWAADLWGVVWDWMASGLDKDYLKPDD$ (서열번호:1172)
LSTAADVWGVVWDWMASGLDKDYLKPDD$ (서열번호:1173)
*LSTAADVWGVVWDWMASGLDKDYLKPDD$ (서열번호:1174)
LSWAADVWGVVWDWMASGLDKDYLKPDD$ (서열번호:1175)
*LSWAADVWGVVWDWMASGLDKDYLKPDD$ (서열번호:1176)
LSTAADMQAVVWDWMASGLDKDYLKPDD$ (서열번호:1177)
*LSTAADMQAVVWDWMASGLDKDYLKPDD$ (서열번호:1178)
LSWAADMQAVVWDWMASGLDKDYLKPDD$ (서열번호:1179)
*LSWAADMQAVVWDWMASGLDKDYLKPDD$ (서열번호:1180)
LSTAADLQAVVWDWMASGLDKDYLKPDD$ (서열번호:1181)
*LSTAADLQAVVWDWMASGLDKDYLKPDD$ (서열번호:1182)
LSWAADLQAVVWDWMASGLDKDYLKPDD$ (서열번호:1183)
*LSWAADLQAVVWDWMASGLDKDYLKPDD$ (서열번호:1184)
LSTAADVQAVVWDWMASGLDKDYLKPDD$ (서열번호:1185)
*LSTAADVQAVVWDWMASGLDKDYLKPDD$ (서열번호:1186)
LSWAADVQAVVWDWMASGLDKDYLKPDD$ (서열번호:1187)
*LSWAADVQAVVWDWMASGLDKDYLKPDD$ (서열번호:1188)
LSTAADMWAVVWDWMASGLDKDYLKPDD$ (서열번호:1189)
*LSTAADMWAVVWDWMASGLDKDYLKPDD$ (서열번호:1190)
LSWAADMWAVVWDWMASGLDKDYLKPDD$ (서열번호:1191)
*LSWAADMWAVVWDWMASGLDKDYLKPDD$ (서열번호:1192)
LSTAADLWAVVWDWMASGLDKDYLKPDD$ (서열번호:1193)
*LSTAADLWAVVWDWMASGLDKDYLKPDD$ (서열번호:1194)
LSWAADLWAVVWDWMASGLDKDYLKPDD$ (서열번호:1195)
*LSWAADLWAVVWDWMASGLDKDYLKPDD$ (서열번호:1196)
LSTAADVWAVVWDWMASGLDKDYLKPDD$ (서열번호:1197)
*LSTAADVWAVVWDWMASGLDKDYLKPDD$ (서열번호:1198)
LSWAADVWAVVWDWMASGLDKDYLKPDD$ (서열번호:1199)
*LSWAADVWAVVWDWMASGLDKDYLKPDD$ (서열번호:1200)
LSTAADMQGVVTDGLASGLDKDYLKPDD$ (서열번호:1201)
*LSTAADMQGVVTDGLASGLDKDYLKPDD$ (서열번호:1202)
LSWAADMQGVVTDGLASGLDKDYLKPDD$ (서열번호:1203)
*LSWAADMQGVVTDGLASGLDKDYLKPDD$ (서열번호:1204)
LSTAADLQGVVTDGLASGLDKDYLKPDD$ (서열번호:1205)
*LSTAADLQGVVTDGLASGLDKDYLKPDD$ (서열번호:1206)
LSWAADLQGVVTDGLASGLDKDYLKPDD$ (서열번호:1207)
*LSWAADLQGVVTDGLASGLDKDYLKPDD$ (서열번호:1208)
LSTAADVQGVVTDGLASGLDKDYLKPDD$ (서열번호:1209)
*LSTAADVQGVVTDGLASGLDKDYLKPDD$ (서열번호:1210)
LSWAADVQGVVTDGLASGLDKDYLKPDD$ (서열번호:1211)
*LSWAADVQGVVTDGLASGLDKDYLKPDD$ (서열번호:1212)
LSTAADMWGVVTDGLASGLDKDYLKPDD$ (서열번호:1213)
*LSTAADMWGVVTDGLASGLDKDYLKPDD$ (서열번호:1214)
LSWAADMWGVVTDGLASGLDKDYLKPDD$ (서열번호:1215)
*LSWAADMWGVVTDGLASGLDKDYLKPDD$ (서열번호:1216)
LSTAADLWGVVTDGLASGLDKDYLKPDD$ (서열번호:1217)
*LSTAADLWGVVTDGLASGLDKDYLKPDD$ (서열번호:1218)
LSWAADLWGVVTDGLASGLDKDYLKPDD$ (서열번호:1219)
*LSWAADLWGVVTDGLASGLDKDYLKPDD$ (서열번호:1220)
LSTAADVWGVVTDGLASGLDKDYLKPDD$ (서열번호:1221)
*LSTAADVWGVVTDGLASGLDKDYLKPDD$ (서열번호:1222)
LSWAADVWGVVTDGLASGLDKDYLKPDD$ (서열번호:1223)
*LSWAADVWGVVTDGLASGLDKDYLKPDD$ (서열번호:1224)
LSTAADMQAVVTDGLASGLDKDYLKPDD$ (서열번호:1225)
*LSTAADMQAVVTDGLASGLDKDYLKPDD$ (서열번호:1226)
LSWAADMQAVVTDGLASGLDKDYLKPDD$ (서열번호:1227)
*LSWAADMQAVVTDGLASGLDKDYLKPDD$ (서열번호:1228)
LSTAADLQAVVTDGLASGLDKDYLKPDD$ (서열번호:1229)
*LSTAADLQAVVTDGLASGLDKDYLKPDD$ (서열번호:1230)
LSWAADLQAVVTDGLASGLDKDYLKPDD$ (서열번호:1231)
*LSWAADLQAVVTDGLASGLDKDYLKPDD$ (서열번호:1232)
LSTAADVQAVVTDGLASGLDKDYLKPDD$ (서열번호:1233)
*LSTAADVQAVVTDGLASGLDKDYLKPDD$ (서열번호:1234)
LSWAADVQAVVTDGLASGLDKDYLKPDD$ (서열번호:1235)
*LSWAADVQAVVTDGLASGLDKDYLKPDD$ (서열번호:1236)
LSTAADMWAVVTDGLASGLDKDYLKPDD$ (서열번호:1237)
*LSTAADMWAVVTDGLASGLDKDYLKPDD$ (서열번호:1238)
LSWAADMWAVVTDGLASGLDKDYLKPDD$ (서열번호:1239)
*LSWAADMWAVVTDGLASGLDKDYLKPDD$ (서열번호:1240)
LSTAADLWAVVTDGLASGLDKDYLKPDD$ (서열번호:1241)
*LSTAADLWAVVTDGLASGLDKDYLKPDD$ (서열번호:1242)
LSWAADLWAVVTDGLASGLDKDYLKPDD$ (서열번호:1243)
*LSWAADLWAVVTDGLASGLDKDYLKPDD$ (서열번호:1244)
LSTAADVWAVVTDGLASGLDKDYLKPDD$ (서열번호:1245)
*LSTAADVWAVVTDGLASGLDKDYLKPDD$ (서열번호:1246)
LSWAADVWAVVTDGLASGLDKDYLKPDD$ (서열번호:1247)
*LSWAADVWAVVTDGLASGLDKDYLKPDD$ (서열번호:1248)
LSTAADMQGVVWDGLASGLDKDYLKPDD$ (서열번호:1249)
*LSTAADMQGVVWDGLASGLDKDYLKPDD$ (서열번호:1250)
LSWAADMQGVVWDGLASGLDKDYLKPDD$ (서열번호:1251)
*LSWAADMQGVVWDGLASGLDKDYLKPDD$ (서열번호:1252)
LSTAADLQGVVWDGLASGLDKDYLKPDD$ (서열번호:1253)
*LSTAADLQGVVWDGLASGLDKDYLKPDD$ (서열번호:1254)
LSWAADLQGVVWDGLASGLDKDYLKPDD$ (서열번호:1255)
*LSWAADLQGVVWDGLASGLDKDYLKPDD$ (서열번호:1256)
LSTAADVQGVVWDGLASGLDKDYLKPDD$ (서열번호:1257)
*LSTAADVQGVVWDGLASGLDKDYLKPDD$ (서열번호:1258)
LSWAADVQGVVWDGLASGLDKDYLKPDD$ (서열번호:1259)
*LSWAADVQGVVWDGLASGLDKDYLKPDD$ (서열번호:1260)
LSTAADMWGVVWDGLASGLDKDYLKPDD$ (서열번호:1261)
*LSTAADMWGVVWDGLASGLDKDYLKPDD$ (서열번호:1262)
LSWAADMWGVVWDGLASGLDKDYLKPDD$ (서열번호:1263)
*LSWAADMWGVVWDGLASGLDKDYLKPDD$ (서열번호:1264)
LSTAADLWGVVWDGLASGLDKDYLKPDD$ (서열번호:1265)
*LSTAADLWGVVWDGLASGLDKDYLKPDD$ (서열번호:1266)
LSWAADLWGVVWDGLASGLDKDYLKPDD$ (서열번호:1267)
*LSWAADLWGVVWDGLASGLDKDYLKPDD$ (서열번호:1268)
LSTAADVWGVVWDGLASGLDKDYLKPDD$ (서열번호:1269)
*LSTAADVWGVVWDGLASGLDKDYLKPDD$ (서열번호:1270)
LSWAADVWGVVWDGLASGLDKDYLKPDD$ (서열번호:1271)
*LSWAADVWGVVWDGLASGLDKDYLKPDD$ (서열번호:1272)
LSTAADMQAVVWDGLASGLDKDYLKPDD$ (서열번호:1273)
*LSTAADMQAVVWDGLASGLDKDYLKPDD$ (서열번호:1274)
LSWAADMQAVVWDGLASGLDKDYLKPDD$ (서열번호:1275)
*LSWAADMQAVVWDGLASGLDKDYLKPDD$ (서열번호:1276)
LSTAADLQAVVWDGLASGLDKDYLKPDD$ (서열번호:1277)
*LSTAADLQAVVWDGLASGLDKDYLKPDD$ (서열번호:1278)
LSWAADLQAVVWDGLASGLDKDYLKPDD$ (서열번호:1279)
*LSWAADLQAVVWDGLASGLDKDYLKPDD$ (서열번호:1280)
LSTAADVQAVVWDGLASGLDKDYLKPDD$ (서열번호:1281)
*LSTAADVQAVVWDGLASGLDKDYLKPDD$ (서열번호:1282)
LSWAADVQAVVWDGLASGLDKDYLKPDD$ (서열번호:1283)
*LSWAADVQAVVWDGLASGLDKDYLKPDD$ (서열번호:1284)
LSTAADMWAVVWDGLASGLDKDYLKPDD$ (서열번호:1285)
*LSTAADMWAVVWDGLASGLDKDYLKPDD$ (서열번호:1286)
LSWAADMWAVVWDGLASGLDKDYLKPDD$ (서열번호:1287)
*LSWAADMWAVVWDGLASGLDKDYLKPDD$ (서열번호:1288)
LSTAADLWAVVWDGLASGLDKDYLKPDD$ (서열번호:1289)
*LSTAADLWAVVWDGLASGLDKDYLKPDD$ (서열번호:1290)
LSWAADLWAVVWDGLASGLDKDYLKPDD$ (서열번호:1291)
*LSWAADLWAVVWDGLASGLDKDYLKPDD$ (서열번호:1292)
LSTAADVWAVVWDGLASGLDKDYLKPDD$ (서열번호:1293)
*LSTAADVWAVVWDGLASGLDKDYLKPDD$ (서열번호:1294)
LSWAADVWAVVWDGLASGLDKDYLKPDD$ (서열번호:1295)
*LSWAADVWAVVWDGLASGLDKDYLKPDD$ (서열번호:1296)
LSTAADMQGVVTDTLASGLDKDYLKPDD$ (서열번호:1297)
*LSTAADMQGVVTDTLASGLDKDYLKPDD$ (서열번호:1298)
LSWAADMQGVVTDTLASGLDKDYLKPDD$ (서열번호:1299)
*LSWAADMQGVVTDTLASGLDKDYLKPDD$ (서열번호:1300)
LSTAADLQGVVTDTLASGLDKDYLKPDD$ (서열번호:1301)
*LSTAADLQGVVTDTLASGLDKDYLKPDD$ (서열번호:1302)
LSWAADLQGVVTDTLASGLDKDYLKPDD$ (서열번호:1303)
*LSWAADLQGVVTDTLASGLDKDYLKPDD$ (서열번호:1304)
LSTAADVQGVVTDTLASGLDKDYLKPDD$ (서열번호:1305)
*LSTAADVQGVVTDTLASGLDKDYLKPDD$ (서열번호:1306)
LSWAADVQGVVTDTLASGLDKDYLKPDD$ (서열번호:1307)
*LSWAADVQGVVTDTLASGLDKDYLKPDD$ (서열번호:1308)
LSTAADMWGVVTDTLASGLDKDYLKPDD$ (서열번호:1309)
*LSTAADMWGVVTDTLASGLDKDYLKPDD$ (서열번호:1310)
LSWAADMWGVVTDTLASGLDKDYLKPDD$ (서열번호:1311)
*LSWAADMWGVVTDTLASGLDKDYLKPDD$ (서열번호:1312)
LSTAADLWGVVTDTLASGLDKDYLKPDD$ (서열번호:1313)
*LSTAADLWGVVTDTLASGLDKDYLKPDD$ (서열번호:1314)
LSWAADLWGVVTDTLASGLDKDYLKPDD$ (서열번호:1315)
*LSWAADLWGVVTDTLASGLDKDYLKPDD$ (서열번호:1316)
LSTAADVWGVVTDTLASGLDKDYLKPDD$ (서열번호:1317)
*LSTAADVWGVVTDTLASGLDKDYLKPDD$ (서열번호:1318)
LSWAADVWGVVTDTLASGLDKDYLKPDD$ (서열번호:1319)
*LSWAADVWGVVTDTLASGLDKDYLKPDD$ (서열번호:1320)
LSTAADMQAVVTDTLASGLDKDYLKPDD$ (서열번호:1321)
*LSTAADMQAVVTDTLASGLDKDYLKPDD$ (서열번호:1322)
LSWAADMQAVVTDTLASGLDKDYLKPDD$ (서열번호:1323)
*LSWAADMQAVVTDTLASGLDKDYLKPDD$ (서열번호:1324)
LSTAADLQAVVTDTLASGLDKDYLKPDD$ (서열번호:1325)
*LSTAADLQAVVTDTLASGLDKDYLKPDD$ (서열번호:1326)
LSWAADLQAVVTDTLASGLDKDYLKPDD$ (서열번호:1327)
*LSWAADLQAVVTDTLASGLDKDYLKPDD$ (서열번호:1328)
LSTAADVQAVVTDTLASGLDKDYLKPDD$ (서열번호:1329)
*LSTAADVQAVVTDTLASGLDKDYLKPDD$ (서열번호:1330)
LSWAADVQAVVTDTLASGLDKDYLKPDD$ (서열번호:1331)
*LSWAADVQAVVTDTLASGLDKDYLKPDD$ (서열번호:1332)
LSTAADMWAVVTDTLASGLDKDYLKPDD$ (서열번호:1333)
*LSTAADMWAVVTDTLASGLDKDYLKPDD$ (서열번호:1334)
LSWAADMWAVVTDTLASGLDKDYLKPDD$ (서열번호:1335)
*LSWAADMWAVVTDTLASGLDKDYLKPDD$ (서열번호:1336)
LSTAADLWAVVTDTLASGLDKDYLKPDD$ (서열번호:1337)
*LSTAADLWAVVTDTLASGLDKDYLKPDD$ (서열번호:1338)
LSWAADLWAVVTDTLASGLDKDYLKPDD$ (서열번호:1339)
*LSWAADLWAVVTDTLASGLDKDYLKPDD$ (서열번호:1340)
LSTAADVWAVVTDTLASGLDKDYLKPDD$ (서열번호:1341)
*LSTAADVWAVVTDTLASGLDKDYLKPDD$ (서열번호:1342)
LSWAADVWAVVTDTLASGLDKDYLKPDD$ (서열번호:1343)
*LSWAADVWAVVTDTLASGLDKDYLKPDD$ (서열번호:1344)
LSTAADMQGVVWDTLASGLDKDYLKPDD$ (서열번호:1345)
*LSTAADMQGVVWDTLASGLDKDYLKPDD$ (서열번호:1346)
LSWAADMQGVVWDTLASGLDKDYLKPDD$ (서열번호:1347)
*LSWAADMQGVVWDTLASGLDKDYLKPDD$ (서열번호:1348)
LSTAADLQGVVWDTLASGLDKDYLKPDD$ (서열번호:1349)
*LSTAADLQGVVWDTLASGLDKDYLKPDD$ (서열번호:1350)
LSWAADLQGVVWDTLASGLDKDYLKPDD$ (서열번호:1351)
*LSWAADLQGVVWDTLASGLDKDYLKPDD$ (서열번호:1352)
LSTAADVQGVVWDTLASGLDKDYLKPDD$ (서열번호:1353)
*LSTAADVQGVVWDTLASGLDKDYLKPDD$ (서열번호:1354)
LSWAADVQGVVWDTLASGLDKDYLKPDD$ (서열번호:1355)
*LSWAADVQGVVWDTLASGLDKDYLKPDD$ (서열번호:1356)
LSTAADMWGVVWDTLASGLDKDYLKPDD$ (서열번호:1357)
*LSTAADMWGVVWDTLASGLDKDYLKPDD$ (서열번호:1358)
LSWAADMWGVVWDTLASGLDKDYLKPDD$ (서열번호:1359)
*LSWAADMWGVVWDTLASGLDKDYLKPDD$ (서열번호:1360)
LSTAADLWGVVWDTLASGLDKDYLKPDD$ (서열번호:1361)
*LSTAADLWGVVWDTLASGLDKDYLKPDD$ (서열번호:1362)
LSWAADLWGVVWDTLASGLDKDYLKPDD$ (서열번호:1363)
*LSWAADLWGVVWDTLASGLDKDYLKPDD$ (서열번호:1364)
LSTAADVWGVVWDTLASGLDKDYLKPDD$ (서열번호:1365)
*LSTAADVWGVVWDTLASGLDKDYLKPDD$ (서열번호:1366)
LSWAADVWGVVWDTLASGLDKDYLKPDD$ (서열번호:1367)
*LSWAADVWGVVWDTLASGLDKDYLKPDD$ (서열번호:1368)
LSTAADMQAVVWDTLASGLDKDYLKPDD$ (서열번호:1369)
*LSTAADMQAVVWDTLASGLDKDYLKPDD$ (서열번호:1370)
LSWAADMQAVVWDTLASGLDKDYLKPDD$ (서열번호:1371)
*LSWAADMQAVVWDTLASGLDKDYLKPDD$ (서열번호:1372)
LSTAADLQAVVWDTLASGLDKDYLKPDD$ (서열번호:1373)
*LSTAADLQAVVWDTLASGLDKDYLKPDD$ (서열번호:1374)
LSWAADLQAVVWDTLASGLDKDYLKPDD$ (서열번호:1375)
*LSWAADLQAVVWDTLASGLDKDYLKPDD$ (서열번호:1376)
LSTAADVQAVVWDTLASGLDKDYLKPDD$ (서열번호:1377)
*LSTAADVQAVVWDTLASGLDKDYLKPDD$ (서열번호:1378)
LSWAADVQAVVWDTLASGLDKDYLKPDD$ (서열번호:1379)
*LSWAADVQAVVWDTLASGLDKDYLKPDD$ (서열번호:1380)
LSTAADMWAVVWDTLASGLDKDYLKPDD$ (서열번호:1381)
*LSTAADMWAVVWDTLASGLDKDYLKPDD$ (서열번호:1382)
LSWAADMWAVVWDTLASGLDKDYLKPDD$ (서열번호:1383)
*LSWAADMWAVVWDTLASGLDKDYLKPDD$ (서열번호:1384)
LSTAADLWAVVWDTLASGLDKDYLKPDD$ (서열번호:1385)
*LSTAADLWAVVWDTLASGLDKDYLKPDD$ (서열번호:1386)
LSWAADLWAVVWDTLASGLDKDYLKPDD$ (서열번호:1387)
*LSWAADLWAVVWDTLASGLDKDYLKPDD$ (서열번호:1388)
LSTAADVWAVVWDTLASGLDKDYLKPDD$ (서열번호:1389)
*LSTAADVWAVVWDTLASGLDKDYLKPDD$ (서열번호:1390)
LSWAADVWAVVWDTLASGLDKDYLKPDD$ (서열번호:1391)
*LSWAADVWAVVWDTLASGLDKDYLKPDD$ (서열번호:1392)
LSTAADMQGVVTDWLASGLDKDYLKPDD$ (서열번호:1393)
*LSTAADMQGVVTDWLASGLDKDYLKPDD$ (서열번호:1394)
LSWAADMQGVVTDWLASGLDKDYLKPDD$ (서열번호:1395)
*LSWAADMQGVVTDWLASGLDKDYLKPDD$ (서열번호:1396)
LSTAADLQGVVTDWLASGLDKDYLKPDD$ (서열번호:1397)
*LSTAADLQGVVTDWLASGLDKDYLKPDD$ (서열번호:1398)
LSWAADLQGVVTDWLASGLDKDYLKPDD$ (서열번호:1399)
*LSWAADLQGVVTDWLASGLDKDYLKPDD$ (서열번호:1400)
LSTAADVQGVVTDWLASGLDKDYLKPDD$ (서열번호:1401)
*LSTAADVQGVVTDWLASGLDKDYLKPDD$ (서열번호:1402)
LSWAADVQGVVTDWLASGLDKDYLKPDD$ (서열번호:1403)
*LSWAADVQGVVTDWLASGLDKDYLKPDD$ (서열번호:1404)
LSTAADMWGVVTDWLASGLDKDYLKPDD$ (서열번호:1405)
*LSTAADMWGVVTDWLASGLDKDYLKPDD$ (서열번호:1406)
LSWAADMWGVVTDWLASGLDKDYLKPDD$ (서열번호:1407)
*LSWAADMWGVVTDWLASGLDKDYLKPDD$ (서열번호:1408)
LSTAADLWGVVTDWLASGLDKDYLKPDD$ (서열번호:1409)
*LSTAADLWGVVTDWLASGLDKDYLKPDD$ (서열번호:1410)
LSWAADLWGVVTDWLASGLDKDYLKPDD$ (서열번호:1411)
*LSWAADLWGVVTDWLASGLDKDYLKPDD$ (서열번호:1412)
LSTAADVWGVVTDWLASGLDKDYLKPDD$ (서열번호:1413)
*LSTAADVWGVVTDWLASGLDKDYLKPDD$ (서열번호:1414)
LSWAADVWGVVTDWLASGLDKDYLKPDD$ (서열번호:1415)
*LSWAADVWGVVTDWLASGLDKDYLKPDD$ (서열번호:1416)
LSTAADMQAVVTDWLASGLDKDYLKPDD$ (서열번호:1417)
*LSTAADMQAVVTDWLASGLDKDYLKPDD$ (서열번호:1418)
LSWAADMQAVVTDWLASGLDKDYLKPDD$ (서열번호:1419)
*LSWAADMQAVVTDWLASGLDKDYLKPDD$ (서열번호:1420)
LSTAADLQAVVTDWLASGLDKDYLKPDD$ (서열번호:1421)
*LSTAADLQAVVTDWLASGLDKDYLKPDD$ (서열번호:1422)
LSWAADLQAVVTDWLASGLDKDYLKPDD$ (서열번호:1423)
*LSWAADLQAVVTDWLASGLDKDYLKPDD$ (서열번호:1424)
LSTAADVQAVVTDWLASGLDKDYLKPDD$ (서열번호:1425)
*LSTAADVQAVVTDWLASGLDKDYLKPDD$ (서열번호:1426)
LSWAADVQAVVTDWLASGLDKDYLKPDD$ (서열번호:1427)
*LSWAADVQAVVTDWLASGLDKDYLKPDD$ (서열번호:1428)
LSTAADMWAVVTDWLASGLDKDYLKPDD$ (서열번호:1429)
*LSTAADMWAVVTDWLASGLDKDYLKPDD$ (서열번호:1430)
LSWAADMWAVVTDWLASGLDKDYLKPDD$ (서열번호:1431)
*LSWAADMWAVVTDWLASGLDKDYLKPDD$ (서열번호:1432)
LSTAADLWAVVTDWLASGLDKDYLKPDD$ (서열번호:1433)
*LSTAADLWAVVTDWLASGLDKDYLKPDD$ (서열번호:1434)
LSWAADLWAVVTDWLASGLDKDYLKPDD$ (서열번호:1435)
*LSWAADLWAVVTDWLASGLDKDYLKPDD$ (서열번호:1436)
LSTAADVWAVVTDWLASGLDKDYLKPDD$ (서열번호:1437)
*LSTAADVWAVVTDWLASGLDKDYLKPDD$ (서열번호:1438)
LSWAADVWAVVTDWLASGLDKDYLKPDD$ (서열번호:1439)
*LSWAADVWAVVTDWLASGLDKDYLKPDD$ (서열번호:1440)
LSTAADMQGVVWDWLASGLDKDYLKPDD$ (서열번호:1441)
*LSTAADMQGVVWDWLASGLDKDYLKPDD$ (서열번호:1442)
LSWAADMQGVVWDWLASGLDKDYLKPDD$ (서열번호:1443)
*LSWAADMQGVVWDWLASGLDKDYLKPDD$ (서열번호:1444)
LSTAADLQGVVWDWLASGLDKDYLKPDD$ (서열번호:1445)
*LSTAADLQGVVWDWLASGLDKDYLKPDD$ (서열번호:1446)
LSWAADLQGVVWDWLASGLDKDYLKPDD$ (서열번호:1447)
*LSWAADLQGVVWDWLASGLDKDYLKPDD$ (서열번호:1448)
LSTAADVQGVVWDWLASGLDKDYLKPDD$ (서열번호:1449)
*LSTAADVQGVVWDWLASGLDKDYLKPDD$ (서열번호:1450)
LSWAADVQGVVWDWLASGLDKDYLKPDD$ (서열번호:1451)
*LSWAADVQGVVWDWLASGLDKDYLKPDD$ (서열번호:1452)
LSTAADMWGVVWDWLASGLDKDYLKPDD$ (서열번호:1453)
*LSTAADMWGVVWDWLASGLDKDYLKPDD$ (서열번호:1454)
LSWAADMWGVVWDWLASGLDKDYLKPDD$ (서열번호:1455)
*LSWAADMWGVVWDWLASGLDKDYLKPDD$ (서열번호:1456)
LSTAADLWGVVWDWLASGLDKDYLKPDD$ (서열번호:1457)
*LSTAADLWGVVWDWLASGLDKDYLKPDD$ (서열번호:1458)
LSWAADLWGVVWDWLASGLDKDYLKPDD$ (서열번호:1459)
*LSWAADLWGVVWDWLASGLDKDYLKPDD$ (서열번호:1460)
LSTAADVWGVVWDWLASGLDKDYLKPDD$ (서열번호:1461)
*LSTAADVWGVVWDWLASGLDKDYLKPDD$ (서열번호:1462)
LSWAADVWGVVWDWLASGLDKDYLKPDD$ (서열번호:1463)
*LSWAADVWGVVWDWLASGLDKDYLKPDD$ (서열번호:1464)
LSTAADMQAVVWDWLASGLDKDYLKPDD$ (서열번호:1465)
*LSTAADMQAVVWDWLASGLDKDYLKPDD$ (서열번호:1466)
LSWAADMQAVVWDWLASGLDKDYLKPDD$ (서열번호:1467)
*LSWAADMQAVVWDWLASGLDKDYLKPDD$ (서열번호:1468)
LSTAADLQAVVWDWLASGLDKDYLKPDD$ (서열번호:1469)
*LSTAADLQAVVWDWLASGLDKDYLKPDD$ (서열번호:1470)
LSWAADLQAVVWDWLASGLDKDYLKPDD$ (서열번호:1471)
*LSWAADLQAVVWDWLASGLDKDYLKPDD$ (서열번호:1472)
LSTAADVQAVVWDWLASGLDKDYLKPDD$ (서열번호:1473)
*LSTAADVQAVVWDWLASGLDKDYLKPDD$ (서열번호:1474)
LSWAADVQAVVWDWLASGLDKDYLKPDD$ (서열번호:1475)
*LSWAADVQAVVWDWLASGLDKDYLKPDD$ (서열번호:1476)
LSTAADMWAVVWDWLASGLDKDYLKPDD$ (서열번호:1477)
*LSTAADMWAVVWDWLASGLDKDYLKPDD$ (서열번호:1478)
LSWAADMWAVVWDWLASGLDKDYLKPDD$ (서열번호:1479)
*LSWAADMWAVVWDWLASGLDKDYLKPDD$ (서열번호:1480)
LSTAADLWAVVWDWLASGLDKDYLKPDD$ (서열번호:1481)
*LSTAADLWAVVWDWLASGLDKDYLKPDD$ (서열번호:1482)
LSWAADLWAVVWDWLASGLDKDYLKPDD$ (서열번호:1483)
*LSWAADLWAVVWDWLASGLDKDYLKPDD$ (서열번호:1484)
LSTAADVWAVVWDWLASGLDKDYLKPDD$ (서열번호:1485)
*LSTAADVWAVVWDWLASGLDKDYLKPDD$ (서열번호:I486)
LSWAADVWAVVWDWLASGLDKDYLKPDD$ (서열번호:1487)
*LSWAADVWAVVWDWLASGLDKDYLKPDD$ (서열번호:1488)
LSTAADMQGVVTDGVASGLDKDYLKPDD$ (서열번호:1489)
*LSTAADMQGVVTDGVASGLDKDYLKPDD$ (서열번호:1490)
LSWAADMQGVVTDGVASGLDKDYLKPDD$ (서열번호:1491)
*LSWAADMQGVVTDGVASGLDKDYLKPDD$ (서열번호:1492)
LSTAADLQGVVTDGVASGLDKDYLKPDD$ (서열번호:1493)
*LSTAADLQGVVTDGVASGLDKDYLKPDD$ (서열번호:1494)
LSWAADLQGVVTDGVASGLDKDYLKPDD$ (서열번호:1495)
*LSWAADLQGVVTDGVASGLDKDYLKPDD$ (서열번호:1496)
LSTAADVQGVVTDGVASGLDKDYLKPDD$ (서열번호:1497)
*LSTAADVQGVVTDGVASGLDKDYLKPDD$ (서열번호:1498)
LSWAADVQGVVTDGVASGLDKDYLKPDD$ (서열번호:1499)
*LSWAADVQGVVTDGVASGLDKDYLKPDD$ (서열번호:1500)
LSTAADMWGVVTDGVASGLDKDYLKPDD$ (서열번호:1501)
*LSTAADMWGVVTDGVASGLDKDYLKPDD$ (서열번호:1502)
LSWAADMWGVVTDGVASGLDKDYLKPDD$ (서열번호:1503)
*LSWAADMWGVVTDGVASGLDKDYLKPDD$ (서열번호:1504)
LSTAADLWGVVTDGVASGLDKDYLKPDD$ (서열번호:1505)
*LSTAADLWGVVTDGVASGLDKDYLKPDD$ (서열번호:1506)
LSWAADLWGVVTDGVASGLDKDYLKPDD$ (서열번호:1507)
*LSWAADLWGVVTDGVASGLDKDYLKPDD$ (서열번호:1508)
LSTAADVWGVVTDGVASGLDKDYLKPDD$ (서열번호:1509)
*LSTAADVWGVVTDGVASGLDKDYLKPDD$ (서열번호:1510)
LSWAADVWGVVTDGVASGLDKDYLKPDD$ (서열번호:1511)
*LSWAADVWGVVTDGVASGLDKDYLKPDD$ (서열번호:1512)
LSTAADMQAVVTDGVASGLDKDYLKPDD$ (서열번호:1513)
*LSTAADMQAVVTDGVASGLDKDYLKPDD$ (서열번호:1514)
LSWAADMQAVVTDGVASGLDKDYLKPDD$ (서열번호:1515)
*LSWAADMQAVVTDGVASGLDKDYLKPDD$ (서열번호:1516)
LSTAADLQAVVTDGVASGLDKDYLKPDD$ (서열번호:1517)
*LSTAADLQAVVTDGVASGLDKDYLKPDD$ (서열번호:1518)
LSWAADLQAVVTDGVASGLDKDYLKPDD$ (서열번호:1519)
*LSWAADLQAVVTDGVASGLDKDYLKPDD$ (서열번호:1520)
LSTAADVQAVVTDGVASGLDKDYLKPDD$ (서열번호:1521)
*LSTAADVQAVVTDGVASGLDKDYLKPDD$ (서열번호:1522)
LSWAADVQAVVTDGVASGLDKDYLKPDD$ (서열번호:1523)
*LSWAADVQAVVTDGVASGLDKDYLKPDD$ (서열번호:1524)
LSTAADMWAVVTDGVASGLDKDYLKPDD$ (서열번호:1525)
*LSTAADMWAVVTDGVASGLDKDYLKPDD$ (서열번호:1526)
LSWAADMWAVVTDGVASGLDKDYLKPDD$ (서열번호:1527)
*LSWAADMWAVVTDGVASGLDKDYLKPDD$ (서열번호:1528)
LSTAADLWAVVTDGVASGLDKDYLKPDD$ (서열번호:1529)
*LSTAADLWAVVTDGVASGLDKDYLKPDD$ (서열번호:1530)
LSWAADLWAVVTDGVASGLDKDYLKPDD$ (서열번호:1531)
*LSWAADLWAVVTDGVASGLDKDYLKPDD$ (서열번호:1532)
LSTAADVWAVVTDGVASGLDKDYLKPDD$ (서열번호:1533)
*LSTAADVWAVVTDGVASGLDKDYLKPDD$ (서열번호:1534)
LSWAADVWAVVTDGVASGLDKDYLKPDD$ (서열번호:1535)
*LSWAADVWAVVTDGVASGLDKDYLKPDD$ (서열번호:1536)
LSTAADMQGVVWDGVASGLDKDYLKPDD$ (서열번호:1537)
*LSTAADMQGVVWDGVASGLDKDYLKPDD$ (서열번호:1538)
LSWAADMQGVVWDGVASGLDKDYLKPDD$ (서열번호:1539)
*LSWAADMQGVVWDGVASGLDKDYLKPDD$ (서열번호:1540)
LSTAADLQGVVWDGVASGLDKDYLKPDD$ (서열번호:1541)
*LSTAADLQGVVWDGVASGLDKDYLKPDD$ (서열번호:1542)
LSWAADLQGVVWDGVASGLDKDYLKPDD$ (서열번호:1543)
*LSWAADLQGVVWDGVASGLDKDYLKPDD$ (서열번호:1544)
LSTAADVQGVVWDGVASGLDKDYLKPDD$ (서열번호:1545)
*LSTAADVQGVVWDGVASGLDKDYLKPDD$ (서열번호:1546)
LSWAADVQGVVWDGVASGLDKDYLKPDD$ (서열번호:1547)
*LSWAADVQGVVWDGVASGLDKDYLKPDD$ (서열번호:1548)
LSTAADMWGVVWDGVASGLDKDYLKPDD$ (서열번호:1549)
*LSTAADMWGVVWDGVASGLDKDYLKPDD$ (서열번호:1550)
LSWAADMWGVVWDGVASGLDKDYLKPDD$ (서열번호:1551)
*LSWAADMWGVVWDGVASGLDKDYLKPDD$ (서열번호:1552)
LSTAADLWGVVWDGVASGLDKDYLKPDD$ (서열번호:1553)
*LSTAADLWGVVWDGVASGLDKDYLKPDD$ (서열번호:1554)
LSWAADLWGVVWDGVASGLDKDYLKPDD$ (서열번호:1555)
*LSWAADLWGVVWDGVASGLDKDYLKPDD$ (서열번호:1556)
LSTAADVWGVVWDGVASGLDKDYLKPDD$ (서열번호:1557)
*LSTAADVWGVVWDGVASGLDKDYLKPDD$ (서열번호:1558)
LSWAADVWGVVWDGVASGLDKDYLKPDD$ (서열번호:1559)
^LSWAADVWGVVWDGVASGLDKDYLKPDD$ (서열번호:1560)
LSTAADMQAVVWDGVASGLDKDYLKPDD$ (서열번호:1561)
*LSTAADMQAVVWDGVASGLDKDYLKPDD$ (서열번호:1562)
LSWAADMQAVVWDGVASGLDKDYLKPDD$ (서열번호:1563)
*LSWAADMQAVVWDGVASGLDKDYLKPDD$ (서열번호:1564)
LSTAADLQAVVWDGVASGLDKDYLKPDD$ (서열번호:1565)
*LSTAADLQAVVWDGVASGLDKDYLKPDD$ (서열번호:1566)
LSWAADLQAVVWDGVASGLDKDYLKPDD$ (서열번호:1567)
*LSWAADLQAVVWDGVASGLDKDYLKPDD$ (서열번호:1568)
LSTAADVQAVVWDGVASGLDKDYLKPDD$ (서열번호:1569)
*LSTAADVQAVVWDGVASGLDKDYLKPDD$ (서열번호:1570)
LSWAADVQAVVWDGVASGLDKDYLKPDD$ (서열번호:1571)
*LSWAADVQAVVWDGVASGLDKDYLKPDD$ (서열번호:1572)
LSTAADMWAVVWDGVASGLDKDYLKPDD$ (서열번호:1573)
*LSTAADMWAVVWDGVASGLDKDYLKPDD$ (서열번호:1574)
LSWAADMWAVVWDGVASGLDKDYLKPDD$ (서열번호:1575)
*LSWAADMWAVVWDGVASGLDKDYLKPDD$ (서열번호:1576)
LSTAADLWAVVWDGVASGLDKDYLKPDD$ (서열번호:1577)
*LSTAADLWAVVWDGVASGLDKDYLKPDD$ (서열번호:1578)
LSWAADLWAVVWDGVASGLDKDYLKPDD$ (서열번호:1579)
*LSWAADLWAVVWDGVASGLDKDYLKPDD$ (서열번호:1580)
LSTAADVWAVVWDGVASGLDKDYLKPDD$ (서열번호:1581)
*LSTAADVWAVVWDGVASGLDKDYLKPDD$ (서열번호:1582)
LSWAADVWAVVWDGVASGLDKDYLKPDD$ (서열번호:1583)
*LSWAADVWAVVWDGVASGLDKDYLKPDD$ (서열번호:1584)
LSTAADMQGVVTDTVASGLDKDYLKPDD$ (서열번호:1585)
*LSTAADMQGVVTDTVASGLDKDYLKPDD$ (서열번호:1586)
LSWAADMQGVVTDTVASGLDKDYLKPDD$ (서열번호:1587)
*LSWAADMQGVVTDTVASGLDKDYLKPDD$ (서열번호:1588)
LSTAADLQGVVTDTVASGLDKDYLKPDD$ (서열번호:1589)
*LSTAADLQGVVTDTVASGLDKDYLKPDD$ (서열번호:1590)
LSWAADLQGVVTDTVASGLDKDYLKPDD$ (서열번호:1591)
*LSWAADLQGVVTDTVASGLDKDYLKPDD$ (서열번호:1592)
LSTAADVQGVVTDTVASGLDKDYLKPDD$ (서열번호:1593)
*LSTAADVQGVVTDTVASGLDKDYLKPDD$ (서열번호:1594)
LSWAADVQGVVTDTVASGLDKDYLKPDD$ (서열번호:1595)
*LSWAADVQGVVTDTVASGLDKDYLKPDD$ (서열번호:1596)
LSTAADMWGVVTDTVASGLDKDYLKPDD$ (서열번호:1597)
*LSTAADMWGVVTDTVASGLDKDYLKPDD$ (서열번호:1598)
LSWAADMWGVVTDTVASGLDKDYLKPDD$ (서열번호:1599)
*LSWAADMWGVVTDTVASGLDKDYLKPDD$ (서열번호:1600)
LSTAADLWGVVTDTVASGLDKDYLKPDD$ (서열번호:1601)
*LSTAADLWGVVTDTVASGLDKDYLKPDD$ (서열번호:1602)
LSWAADLWGVVTDTVASGLDKDYLKPDD$ (서열번호:1603)
*LSWAADLWGVVTDTVASGLDKDYLKPDD$ (서열번호:1604)
LSTAADVWGVVTDTVASGLDKDYLKPDD$ (서열번호:1605)
*LSTAADVWGVVTDTVASGLDKDYLKPDD$ (서열번호:1606)
LSWAADVWGVVTDTVASGLDKDYLKPDD$ (서열번호:1607)
*LSWAADVWGVVTDTVASGLDKDYLKPDD$ (서열번호:1608)
LSTAADMQAVVTDTVASGLDKDYLKPDD$ (서열번호:1609)
*LSTAADMQAVVTDTVASGLDKDYLKPDD$ (서열번호:1610)
LSWAADMQAVVTDTVASGLDKDYLKPDD$ (서열번호:1611)
*LSWAADMQAVVTDTVASGLDKDYLKPDD$ (서열번호:1612)
LSTAADLQAVVTDTVASGLDKDYLKPDD$ (서열번호:1613)
*LSTAADLQAVVTDTVASGLDKDYLKPDD$ (서열번호:1614)
LSWAADLQAVVTDTVASGLDKDYLKPDD$ (서열번호:1615)
*LSWAADLQAVVTDTVASGLDKDYLKPDD$ (서열번호:1616)
LSTAADVQAVVTDTVASGLDKDYLKPDD$ (서열번호:1617)
*LSTAADVQAVVTDTVASGLDKDYLKPDD$ (서열번호:1618)
LSWAADVQAVVTDTVASGLDKDYLKPDD$ (서열번호:1619)
*LSWAADVQAVVTDTVASGLDKDYLKPDD$ (서열번호:1620)
LSTAADMWAVVTDTVASGLDKDYLKPDD$ (서열번호:1621)
*LSTAADMWAVVTDTVASGLDKDYLKPDD$ (서열번호:1622)
LSWAADMWAVVTDTVASGLDKDYLKPDD$ (서열번호:1623)
*LSWAADMWAVVTDTVASGLDKDYLKPDD$ (서열번호:1624)
LSTAADLWAVVTDTVASGLDKDYLKPDD$ (서열번호:1625)
*LSTAADLWAVVTDTVASGLDKDYLKPDD$ (서열번호:1626)
LSWAADLWAVVTDTVASGLDKDYLKPDD$ (서열번호:1627)
*LSWAADLWAVVTDTVASGLDKDYLKPDD$ (서열번호:1628)
LSTAADVWAVVTDTVASGLDKDYLKPDD$ (서열번호:1629)
*LSTAADVWAVVTDTVASGLDKDYLKPDD$ (서열번호:1630)
LSWAADVWAVVTDTVASGLDKDYLKPDD$ (서열번호:1631)
*LSWAADVWAVVTDTVASGLDKDYLKPDD$ (서열번호:1632)
LSTAADMQGVVWDTVASGLDKDYLKPDD$ (서열번호:1633)
*LSTAADMQGVVWDTVASGLDKDYLKPDD$ (서열번호:1634)
LSWAADMQGVVWDTVASGLDKDYLKPDD$ (서열번호:1635)
*LSWAADMQGVVWDTVASGLDKDYLKPDD$ (서열번호:1636)
LSTAADLQGVVWDTVASGLDKDYLKPDD$ (서열번호:1637)
*LSTAADLQGVVWDTVASGLDKDYLKPDD$ (서열번호:1638)
LSWAADLQGVVWDTVASGLDKDYLKPDD$ (서열번호:1639)
*LSWAADLQGVVWDTVASGLDKDYLKPDD$ (서열번호:1640)
LSTAADVQGVVWDTVASGLDKDYLKPDD$ (서열번호:1641)
*LSTAADVQGVVWDTVASGLDKDYLKPDD$ (서열번호:1642)
LSWAADVQGVVWDTVASGLDKDYLKPDD$ (서열번호:1643)
*LSWAADVQGVVWDTVASGLDKDYLKPDD$ (서열번호:1644)
LSTAADMWGVVWDTVASGLDKDYLKPDD$ (서열번호:1645)
*LSTAADMWGVVWDTVASGLDKDYLKPDD$ (서열번호:1646)
LSWAADMWGVVWDTVASGLDKDYLKPDD$ (서열번호:1647)
*LSWAADMWGVVWDTVASGLDKDYLKPDD$ (서열번호:1648)
LSTAADLWGVVWDTVASGLDKDYLKPDD$ (서열번호:1649)
*LSTAADLWGVVWDTVASGLDKDYLKPDD$ (서열번호:1650)
LSWAADLWGVVWDTVASGLDKDYLKPDD$ (서열번호:1651)
*LSWAADLWGVVWDTVASGLDKDYLKPDD$ (서열번호:1652)
LSTAADVWGVVWDTVASGLDKDYLKPDD$ (서열번호:1653)
*LSTAADVWGVVWDTVASGLDKDYLKPDD$ (서열번호:1654)
LSWAADVWGVVWDTVASGLDKDYLKPDD$ (서열번호:1655)
*LSWAADVWGVVWDTVASGLDKDYLKPDD$ (서열번호:1656)
LSTAADMQAVVWDTVASGLDKDYLKPDD$ (서열번호:1657)
*LSTAADMQAVVWDTVASGLDKDYLKPDD$ (서열번호:1658)
LSWAADMQAVVWDTVASGLDKDYLKPDD$ (서열번호:1659)
*LSWAADMQAVVWDTVASGLDKDYLKPDD$ (서열번호:1660)
LSTAADLQAVVWDTVASGLDKDYLKPDD$ (서열번호:1661)
*LSTAADLQAVVWDTVASGLDKDYLKPDD$ (서열번호:1662)
LSWAADLQAVVWDTVASGLDKDYLKPDD$ (서열번호:1663)
*LSWAADLQAVVWDTVASGLDKDYLKPDD$ (서열번호:1664)
LSTAADVQAVVWDTVASGLDKDYLKPDD$ (서열번호:1665)
*LSTAADVQAVVWDTVASGLDKDYLKPDD$ (서열번호:1666)
LSWAADVQAVVWDTVASGLDKDYLKPDD$ (서열번호:1667)
*LSWAADVQAVVWDTVASGLDKDYLKPDD$ (서열번호:1668)
LSTAADMWAVVWDTVASGLDKDYLKPDD$ (서열번호:1669)
*LSTAADMWAVVWDTVASGLDKDYLKPDD$ (서열번호:1670)
LSWAADMWAVVWDTVASGLDKDYLKPDD$ (서열번호:1671)
*LSWAADMWAVVWDTVASGLDKDYLKPDD$ (서열번호:1672)
LSTAADLWAVVWDTVASGLDKDYLKPDD$ (서열번호:1673)
*LSTAADLWAVVWDTVASGLDKDYLKPDD$ (서열번호:1674)
LSWAADLWAVVWDTVASGLDKDYLKPDD$ (서열번호:1675)
*LSWAADLWAVVWDTVASGLDKDYLKPDD$ (서열번호:1676)
LSTAADVWAVVWDTVASGLDKDYLKPDD$ (서열번호:1677)
*LSTAADVWAVVWDTVASGLDKDYLKPDD$ (서열번호:1678)
LSWAADVWAVVWDTVASGLDKDYLKPDD$ (서열번호:1679)
*LSWAADVWAVVWDTVASGLDKDYLKPDD$ (서열번호:1680)
LSTAADMQGVVTDWVASGLDKDYLKPDD$ (서열번호:1681)
*LSTAADMQGVVTDWVASGLDKDYLKPDD$ (서열번호:1682)
LSWAADMQGVVTDWVASGLDKDYLKPDD$ (서열번호:1683)
*LSWAADMQGVVTDWVASGLDKDYLKPDD$ (서열번호:1684)
LSTAADLQGVVTDWVASGLDKDYLKPDD$ (서열번호:1685)
*LSTAADLQGVVTDWVASGLDKDYLKPDD$ (서열번호:1686)
LSWAADLQGVVTDWVASGLDKDYLKPDD$ (서열번호:1687)
*LSWAADLQGVVTDWVASGLDKDYLKPDD$ (서열번호:1688)
LSTAADVQGVVTDWVASGLDKDYLKPDD$ (서열번호:1689)
*LSTAADVQGVVTDWVASGLDKDYLKPDD$ (서열번호:1690)
LSWAADVQGVVTDWVASGLDKDYLKPDD$ (서열번호:1691)
*LSWAADVQGVVTDWVASGLDKDYLKPDD$ (서열번호:1692)
LSTAADMWGVVTDWVASGLDKDYLKPDD$ (서열번호:1693)
*LSTAADMWGVVTDWVASGLDKDYLKPDD$ (서열번호:1694)
LSWAADMWGVVTDWVASGLDKDYLKPDD$ (서열번호:1695)
*LSWAADMWGVVTDWVASGLDKDYLKPDD$ (서열번호:1696)
LSTAADLWGVVTDWVASGLDKDYLKPDD$ (서열번호:1697)
*LSTAADLWGVVTDWVASGLDKDYLKPDD$ (서열번호:1698)
LSWAADLWGVVTDWVASGLDKDYLKPDD$ (서열번호:1699)
*LSWAADLWGVVTDWVASGLDKDYLKPDD$ (서열번호:1700)
LSTAADVWGVVTDWVASGLDKDYLKPDD$ (서열번호:1701)
*LSTAADVWGVVTDWVASGLDKDYLKPDD$ (서열번호:1702)
LSWAADVWGVVTDWVASGLDKDYLKPDD$ (서열번호:1703)
*LSWAADVWGVVTDWVASGLDKDYLKPDD$ (서열번호:1704)
LSTAADMQAVVTDWVASGLDKDYLKPDD$ (서열번호:1705)
*LSTAADMQAVVTDWVASGLDKDYLKPDD$ (서열번호:1706)
LSWAADMQAVVTDWVASGLDKDYLKPDD$ (서열번호:1707)
*LSWAADMQAVVTDWVASGLDKDYLKPDD$ (서열번호:1708)
LSTAADLQAVVTDWVASGLDKDYLKPDD$ (서열번호:1709)
*LSTAADLQAVVTDWVASGLDKDYLKPDD$ (서열번호:1710)
LSWAADLQAVVTDWVASGLDKDYLKPDD$ (서열번호:1711)
*LSWAADLQAVVTDWVASGLDKDYLKPDD$ (서열번호:1712)
LSTAADVQAVVTDWVASGLDKDYLKPDD$ (서열번호:1713)
*LSTAADVQAVVTDWVASGLDKDYLKPDD$ (서열번호:1714)
LSWAADVQAVVTDWVASGLDKDYLKPDD$ (서열번호:1715)
*LSWAADVQAVVTDWVASGLDKDYLKPDD$ (서열번호:1716)
LSTAADMWAVVTDWVASGLDKDYLKPDD$ (서열번호:1717)
*LSTAADMWAVVTDWVASGLDKDYLKPDD$ (서열번호:1718)
LSWAADMWAVVTDWVASGLDKDYLKPDD$ (서열번호:1719)
*LSWAADMWAVVTDWVASGLDKDYLKPDD$ (서열번호:1720)
LSTAADLWAVVTDWVASGLDKDYLKPDD$ (서열번호:1721)
*LSTAADLWAVVTDWVASGLDKDYLKPDD$ (서열번호:1722)
LSWAADLWAVVTDWVASGLDKDYLKPDD$ (서열번호:1723)
*LSWAADLWAVVTDWVASGLDKDYLKPDD$ (서열번호:1724)
LSTAADVWAVVTDWVASGLDKDYLKPDD$ (서열번호:1725)
*LSTAADVWAVVTDWVASGLDKDYLKPDD$ (서열번호:1726)
LSWAADVWAVVTDWVASGLDKDYLKPDD$ (서열번호:1727)
*LSWAADVWAVVTDWVASGLDKDYLKPDD$ (서열번호:1728)
LSTAADMQGVVWDWVASGLDKDYLKPDD$ (서열번호:1729)
*LSTAADMQGVVWDWVASGLDKDYLKPDD$ (서열번호:1730)
LSWAADMQGVVWDWVASGLDKDYLKPDD$ (서열번호:1731)
*LSWAADMQGVVWDWVASGLDKDYLKPDD$ (서열번호:1732)
LSTAADLQGVVWDWVASGLDKDYLKPDD$ (서열번호:1733)
*LSTAADLQGVVWDWVASGLDKDYLKPDD$ (서열번호:1734)
LSWAADLQGVVWDWVASGLDKDYLKPDD$ (서열번호:1735)
*LSWAADLQGVVWDWVASGLDKDYLKPDD$ (서열번호:1736)
LSTAADVQGVVWDWVASGLDKDYLKPDD$ (서열번호:1737)
*LSTAADVQGVVWDWVASGLDKDYLKPDD$ (서열번호:1738)
LSWAADVQGVVWDWVASGLDKDYLKPDD$ (서열번호:1739)
*LSWAADVQGVVWDWVASGLDKDYLKPDD$ (서열번호:1740)
LSTAADMWGVVWDWVASGLDKDYLKPDD$ (서열번호:1741)
*LSTAADMWGVVWDWVASGLDKDYLKPDD$ (서열번호:1742)
LSWAADMWGVVWDWVASGLDKDYLKPDD$ (서열번호:1743)
*LSWAADMWGVVWDWVASGLDKDYLKPDD$ (서열번호:1744)
LSTAADLWGVVWDWVASGLDKDYLKPDD$ (서열번호:1745)
*LSTAADLWGVVWDWVASGLDKDYLKPDD$ (서열번호:1746)
LSWAADLWGVVWDWVASGLDKDYLKPDD$ (서열번호:1747)
*LSWAADLWGVVWDWVASGLDKDYLKPDD$ (서열번호:1748)
LSTAADVWGVVWDWVASGLDKDYLKPDD$ (서열번호:1749)
^LSTAADVWGVVWDWVASGLDKDYLKPDD$ (서열번호:1750)
LSWAADVWGVVWDWVASGLDKDYLKPDD$ (서열번호:1751)
*LSWAADVWGVVWDWVASGLDKDYLKPDD$ (서열번호:1752)
LSTAADMQAVVWDWVASGLDKDYLKPDD$ (서열번호:1753)
*LSTAADMQAVVWDWVASGLDKDYLKPDD$ (서열번호:1754)
LSWAADMQAVVWDWVASGLDKDYLKPDD$ (서열번호:1755)
*LSWAADMQAVVWDWVASGLDKDYLKPDD$ (서열번호:1756)
LSTAADLQAVVWDWVASGLDKDYLKPDD$ (서열번호:1757)
*LSTAADLQAVVWDWVASGLDKDYLKPDD$ (서열번호:1758)
LSWAADLQAVVWDWVASGLDKDYLKPDD$ (서열번호:1759)
*LSWAADLQAVVWDWVASGLDKDYLKPDD$ (서열번호:1760)
LSTAADVQAVVWDWVASGLDKDYLKPDD$ (서열번호:1761)
*LSTAADVQAVVWDWVASGLDKDYLKPDD$ (서열번호:1762)
LSWAADVQAVVWDWVASGLDKDYLKPDD$ (서열번호:1763)
*LSWAADVQAVVWDWVASGLDKDYLKPDD$ (서열번호:1764)
LSTAADMWAVVWDWVASGLDKDYLKPDD$ (서열번호:1765)
*LSTAADMWAVVWDWVASGLDKDYLKPDD$ (서열번호:1766)
LSWAADMWAVVWDWVASGLDKDYLKPDD$ (서열번호:1767)
*LSWAADMWAVVWDWVASGLDKDYLKPDD$ (서열번호:1768)
LSTAADLWAVVWDWVASGLDKDYLKPDD$ (서열번호:1769)
*LSTAADLWAVVWDWVASGLDKDYLKPDD$ (서열번호:1770)
LSWAADLWAVVWDWVASGLDKDYLKPDD$ (서열번호:1771)
*LSWAADLWAVVWDWVASGLDKDYLKPDD$ (서열번호:1772)
LSTAADVWAVVWDWVASGLDKDYLKPDD$ (서열번호:1773)
*LSTAADVWAVVWDWVASGLDKDYLKPDD$ (서열번호:1774)
LSWAADVWAVVWDWVASGLDKDYLKPDD$ (서열번호:1775)
*LSWAADVWAVVWDWVASGLDKDYLKPDD$ (서열번호:1776)
*DDPKLYDKDLGSAVWDWVVAWVDAAWSL$ (서열번호:1777)
*DDPKLYDKDLGSAVWDWVVAWVDAAWSL (서열번호:1778)
*DDPKLYDKDLGSAVWDWVVAWVDAATSL$ (서열번호:1779)
*DDPKLYDKDLGSAVWDWVVAWVDAATSL (서열번호:1780)
*DDPKLYDKDLGSAVWDWVVAWLDAAWSL$ (서열번호:1781)
*DDPKLYDKDLGSAVWDWVVAWLDAAWSL (서열번호:1782)
*DDPKLYDKDLGSAVWDWVVAWLDAATSL$ (서열번호:1783)
*DDPKLYDKDLGSAVWDWVVAWLDAATSL (서열번호:1784)
*DDPKLYDKDLGSAVWDWVVAWMDAAWSL$ (서열번호:1785)
*DDPKLYDKDLGSAVWDWVVAWMDAAWSL (서열번호:1786)
*DDPKLYDKDLGSAVWDWVVAWMDAATSL$ (서열번호:1787)
*DDPKLYDKDLGSAVWDWVVAWMDAATSL (서열번호:1788)
*DDPKLYDKDLGSAVWDWVVAQVDAAWSL$ (서열번호:1789)
*DDPKLYDKDLGSAVWDWVVAQVDAAWSL (서열번호:1790)
*DDPKLYDKDLGSAVWDWVVAQVDAATSL$ (서열번호:1791)
*DDPKLYDKDLGSAVWDWVVAQVDAATSL (서열번호:1792)
*DDPKLYDKDLGSAVWDWVVAQLDAAWSL$ (서열번호:1793)
*DDPKLYDKDLGSAVWDWVVAQLDAAWSL (서열번호:1794)
*DDPKLYDKDLGSAVWDWVVAQLDAATSL$ (서열번호:1795)
*DDPKLYDKDLGSAVWDWVVAQLDAATSL (서열번호:1796)
*DDPKLYDKDLGSAVWDWVVAQMDAAWSL$ (서열번호:1797)
*DDPKLYDKDLGSAVWDWVVAQMDAAWSL (서열번호:1798)
*DDPKLYDKDLGSAVWDWVVAQMDAATSL$ (서열번호:1799)
*DDPKLYDKDLGSAVWDWVVAQMDAATSL (서열번호:1800)
*DDPKLYDKDLGSAVWDWVVGWVDAAWSL$ (서열번호:1801)
*DDPKLYDKDLGSAVWDWVVGWVDAAWSL (서열번호:1802)
*DDPKLYDKDLGSAVWDWVVGWVDAATSL$ (서열번호:1803)
*DDPKLYDKDLGSAVWDWVVGWVDAATSL (서열번호:1804)
*DDPKLYDKDLGSAVWDWVVGWLDAAWSL$ (서열번호:1805)
*DDPKLYDKDLGSAVWDWVVGWLDAAWSL (서열번호:1806)
*DDPKLYDKDLGSAVWDWVVGWLDAATSL$ (서열번호:1807)
*DDPKLYDKDLGSAVWDWVVGWLDAATSL (서열번호:1808)
*DDPKLYDKDLGSAVWDWVVGWMDAAWSL$ (서열번호:1809)
*DDPKLYDKDLGSAVWDWVVGWMDAAWSL (서열번호:1810)
*DDPKLYDKDLGSAVWDWVVGWMDAATSL$ (서열번호:1811)
*DDPKLYDKDLGSAVWDWVVGWMDAATSL (서열번호:1812)
*DDPKLYDKDLGSAVWDWVVGQVDAAWSL$ (서열번호:1813)
*DDPKLYDKDLGSAVWDWVVGQVDAAWSL (서열번호:1814)
*DDPKLYDKDLGSAVWDWVVGQVDAATSL$ (서열번호:1815)
*DDPKLYDKDLGSAVWDWVVGQVDAATSL (서열번호:1816)
*DDPKLYDKDLGSAVWDWVVGQLDAAWSL$ (서열번호:1817)
*DDPKLYDKDLGSAVWDWVVGQLDAAWSL (서열번호:1818)
*DDPKLYDKDLGSAVWDWVVGQLDAATSL$ (서열번호:1819)
*DDPKLYDKDLGSAVWDWVVGQLDAATSL (서열번호:1820)
*DDPKLYDKDLGSAVWDWVVGQMDAAWSL$ (서열번호:1821)
*DDPKLYDKDLGSAVWDWVVGQMDAAWSL (서열번호:1822)
*DDPKLYDKDLGSAVWDWVVGQMDAATSL$ (서열번호:1823)
*DDPKLYDKDLGSAVWDWVVGQMDAATSL (서열번호:1824)
*DDPKLYDKDLGSAVWDTVVAWVDAAWSL$ (서열번호:1825)
*DDPKLYDKDLGSAVWDTVVAWVDAAWSL (서열번호:1826)
*DDPKLYDKDLGSAVWDTVVAWVDAATSL$ (서열번호:1827)
*DDPKLYDKDLGSAVWDTVVAWVDAATSL (서열번호:1828)
*DDPKLYDKDLGSAVWDTVVAWLDAAWSL$ (서열번호:1829)
*DDPKLYDKDLGSAVWDTVVAWLDAAWSL (서열번호:1830)
*DDPKLYDKDLGSAVWDTVVAWLDAATSL$ (서열번호:1831)
*DDPKLYDKDLGSAVWDTVVAWLDAATSL (서열번호:1832)
*DDPKLYDKDLGSAVWDTVVAWMDAAWSL$ (서열번호:1833)
*DDPKLYDKDLGSAVWDTVVAWMDAAWSL (서열번호:1834)
*DDPKLYDKDLGSAVWDTVVAWMDAATSL$ (서열번호:1835)
*DDPKLYDKDLGSAVWDTVVAWMDAATSL (서열번호:1836)
*DDPKLYDKDLGSAVWDTVVAQVDAAWSL$ (서열번호:1837)
*DDPKLYDKDLGSAVWDTVVAQVDAAWSL (서열번호:1838)
*DDPKLYDKDLGSAVWDTVVAQVDAATSL$ (서열번호:1839)
*DDPKLYDKDLGSAVWDTVVAQVDAATSL (서열번호:1840)
*DDPKLYDKDLGSAVWDTVVAQLDAAWSL$ (서열번호:1841)
*DDPKLYDKDLGSAVWDTVVAQLDAAWSL (서열번호:1842)
*DDPKLYDKDLGSAVWDTVVAQLDAATSL$ (서열번호:1843)
*DDPKLYDKDLGSAVWDTVVAQLDAATSL (서열번호:1844)
*DDPKLYDKDLGSAVWDTVVAQMDAAWSL$ (서열번호:1845)
*DDPKLYDKDLGSAVWDTVVAQMDAAWSL (서열번호:1846)
*DDPKLYDKDLGSAVWDTVVAQMDAATSL$ (서열번호:1847)
*DDPKLYDKDLGSAVWDTVVAQMDAATSL (서열번호:1848)
*DDPKLYDKDLGSAVWDTVVGWVDAAWSL$ (서열번호:1849)
*DDPKLYDKDLGSAVWDTVVGWVDAAWSL (서열번호:1850)
*DDPKLYDKDLGSAVWDTVVGWVDAATSL$ (서열번호:1851)
*DDPKLYDKDLGSAVWDTVVGWVDAATSL (서열번호:1852)
*DDPKLYDKDLGSAVWDTVVGWLDAAWSL$ (서열번호:1853)
*DDPKLYDKDLGSAVWDTVVGWLDAAWSL (서열번호:1854)
*DDPKLYDKDLGSAVWDTVVGWLDAATSL$ (서열번호:1855)
*DDPKLYDKDLGSAVWDTVVGWLDAATSL (서열번호:1856)
*DDPKLYDKDLGSAVWDTVVGWMDAAWSL$ (서열번호:1857)
*DDPKLYDKDLGSAVWDTVVGWMDAAWSL (서열번호:1858)
*DDPKLYDKDLGSAVWDTVVGWMDAATSL$ (서열번호:1859)
*DDPKLYDKDLGSAVWDTVVGWMDAATSL (서열번호:1860)
*DDPKLYDKDLGSAVWDTVVGQVDAAWSL$ (서열번호:1861)
*DDPKLYDKDLGSAVWDTVVGQVDAAWSL (서열번호:1862)
*DDPKLYDKDLGSAVWDTVVGQVDAATSL$ (서열번호:1863)
*DDPKLYDKDLGSAVWDTVVGQVDAATSL (서열번호:1864)
*DDPKLYDKDLGSAVWDTVVGQLDAAWSL$ (서열번호:1865)
*DDPKLYDKDLGSAVWDTVVGQLDAAWSL (서열번호:1866)
*DDPKLYDKDLGSAVWDTVVGQLDAATSL$ (서열번호:1867)
*DDPKLYDKDLGSAVWDTVVGQLDAATSL (서열번호:1868)
*DDPKLYDKDLGSAVWDTVVGQMDAAWSL$ (서열번호:1869)
*DDPKLYDKDLGSAVWDTVVGQMDAAWSL (서열번호:1870)
*DDPKLYDKDLGSAVWDTVVGQMDAATSL$ (서열번호:1871)
*DDPKLYDKDLGSAVWDTVVGQMDAATSL (서열번호:1872)
*DDPKLYDKDLGSAVTDWVVAWVDAAWSL$ (서열번호:1873)
*DDPKLYDKDLGSAVTDWVVAWVDAAWSL (서열번호:1874)
*DDPKLYDKDLGSAVTDWVVAWVDAATSL$ (서열번호:1875)
*DDPKLYDKDLGSAVTDWVVAWVDAATSL (서열번호:1876)
*DDPKLYDKDLGSAVTDWVVAWLDAAWSL$ (서열번호:1877)
*DDPKLYDKDLGSAVTDWVVAWLDAAWSL (서열번호:1878)
*DDPKLYDKDLGSAVTDWVVAWLDAATSL$ (서열번호:1879)
*DDPKLYDKDLGSAVTDWVVAWLDAATSL (서열번호:1880)
*DDPKLYDKDLGSAVTDWVVAWMDAAWSL$ (서열번호:1881)
*DDPKLYDKDLGSAVTDWVVAWMDAAWSL (서열번호:1882)
*DDPKLYDKDLGSAVTDWVVAWMDAATSL$ (서열번호:1883)
*DDPKLYDKDLGSAVTDWVVAWMDAATSL (서열번호:1884)
*DDPKLYDKDLGSAVTDWVVAQVDAAWSL$ (서열번호:1885)
*DDPKLYDKDLGSAVTDWVVAQVDAAWSL (서열번호:1886)
*DDPKLYDKDLGSAVTDWVVAQVDAATSL$ (서열번호:1887)
*DDPKLYDKDLGSAVTDWVVAQVDAATSL (서열번호:1888)
*DDPKLYDKDLGSAVTDWVVAQLDAAWSL$ (서열번호:1889)
*DDPKLYDKDLGSAVTDWVVAQLDAAWSL (서열번호:1890)
*DDPKLYDKDLGSAVTDWVVAQLDAATSL$ (서열번호:1891)
*DDPKLYDKDLGSAVTDWVVAQLDAATSL (서열번호:1892)
*DDPKLYDKDLGSAVTDWVVAQMDAAWSL$ (서열번호:1893)
*DDPKLYDKDLGSAVTDWVVAQMDAAWSL (서열번호:1894)
*DDPKLYDKDLGSAVTDWVVAQMDAATSL$ (서열번호:1895)
*DDPKLYDKDLGSAVTDWVVAQMDAATSL (서열번호:1896)
*DDPKLYDKDLGSAVTDWVVGWVDAAWSL$ (서열번호:1897)
*DDPKLYDKDLGSAVTDWVVGWVDAAWSL (서열번호:1898)
*DDPKLYDKDLGSAVTDWVVGWVDAATSL$ (서열번호:1899)
*DDPKLYDKDLGSAVTDWVVGWVDAATSL (서열번호:1900)
*DDPKLYDKDLGSAVTDWVVGWLDAAWSL$ (서열번호:1901)
*DDPKLYDKDLGSAVTDWVVGWLDAAWSL (서열번호:1902)
*DDPKLYDKDLGSAVTDWVVGWLDAATSL$ (서열번호:1903)
*DDPKLYDKDLGSAVTDWVVGWLDAATSL (서열번호:1904)
*DDPKLYDKDLGSAVTDWVVGWMDAAWSL$ (서열번호:1905)
*DDPKLYDKDLGSAVTDWVVGWMDAAWSL (서열번호:1906)
*DDPKLYDKDLGSAVTDWVVGWMDAATSL$ (서열번호:1907)
*DDPKLYDKDLGSAVTDWVVGWMDAATSL (서열번호:1908)
*DDPKLYDKDLGSAVTDWVVGQVDAAWSL$ (서열번호:1909)
*DDPKLYDKDLGSAVTDWVVGQVDAAWSL (서열번호:1910)
*DDPKLYDKDLGSAVTDWVVGQVDAATSL$ (서열번호:1911)
*DDPKLYDKDLGSAVTDWVVGQVDAATSL (서열번호:1912)
*DDPKLYDKDLGSAVTDWVVGQLDAAWSL$ (서열번호:1913)
*DDPKLYDKDLGSAVTDWVVGQLDAAWSL (서열번호:1914)
*DDPKLYDKDLGSAVTDWVVGQLDAATSL$ (서열번호:1915)
*DDPKLYDKDLGSAVTDWVVGQLDAATSL (서열번호:1916)
*DDPKLYDKDLGSAVTDWVVGQMDAAWSL$ (서열번호:1917)
*DDPKLYDKDLGSAVTDWVVGQMDAAWSL (서열번호:1918)
*DDPKLYDKDLGSAVTDWVVGQMDAATSL$ (서열번호:1919)
*DDPKLYDKDLGSAVTDWVVGQMDAATSL (서열번호:1920)
*DDPKLYDKDLGSAVTDTVVAWVDAAWSL$ (서열번호:1921)
*DDPKLYDKDLGSAVTDTVVAWVDAAWSL (서열번호:1922)
*DDPKLYDKDLGSAVTDTVVAWVDAATSL$ (서열번호:1923)
*DDPKLYDKDLGSAVTDTVVAWVDAATSL (서열번호:1924)
*DDPKLYDKDLGSAVTDTVVAWLDAAWSL$ (서열번호:1925)
*DDPKLYDKDLGSAVTDTVVAWLDAAWSL (서열번호:1926)
*DDPKLYDKDLGSAVTDTVVAWLDAATSL$ (서열번호:1927)
*DDPKLYDKDLGSAVTDTVVAWLDAATSL (서열번호:1928)
*DDPKLYDKDLGSAVTDTVVAWMDAAWSL$ (서열번호:1929)
*DDPKLYDKDLGSAVTDTVVAWMDAAWSL (서열번호:1930)
*DDPKLYDKDLGSAVTDTVVAWMDAATSL$ (서열번호:1931)
*DDPKLYDKDLGSAVTDTVVAWMDAATSL (서열번호:1932)
*DDPKLYDKDLGSAVTDTVVAQVDAAWSL$ (서열번호:1933)
*DDPKLYDKDLGSAVTDTVVAQVDAAWSL (서열번호:1934)
*DDPKLYDKDLGSAVTDTVVAQVDAATSL$ (서열번호:1935)
*DDPKLYDKDLGSAVTDTVVAQVDAATSL (서열번호:1936)
*DDPKLYDKDLGSAVTDTVVAQLDAAWSL$ (서열번호:1937)
*DDPKLYDKDLGSAVTDTVVAQLDAAWSL (서열번호:1938)
*DDPKLYDKDLGSAVTDTVVAQLDAATSL$ (서열번호:1939)
*DDPKLYDKDLGSAVTDTVVAQLDAATSL (서열번호:1940)
*DDPKLYDKDLGSAVTDTVVAQMDAAWSL$ (서열번호:1941)
*DDPKLYDKDLGSAVTDTVVAQMDAAWSL (서열번호:1942)
*DDPKLYDKDLGSAVTDTVVAQMDAATSL$ (서열번호:1943)
*DDPKLYDKDLGSAVTDTVVAQMDAATSL (서열번호:1944)
*DDPKLYDKDLGSAVTDTVVGWVDAAWSL$ (서열번호:1945)
*DDPKLYDKDLGSAVTDTVVGWVDAAWSL (서열번호:1946)
*DDPKLYDKDLGSAVTDTVVGWVDAATSL$ (서열번호:1947)
*DDPKLYDKDLGSAVTDTVVGWVDAATSL (서열번호:1948)
*DDPKLYDKDLGSAVTDTVVGWLDAAWSL$ (서열번호:1949)
*DDPKLYDKDLGSAVTDTVVGWLDAAWSL (서열번호:1950)
*DDPKLYDKDLGSAVTDTVVGWLDAATSL$ (서열번호:1951)
*DDPKLYDKDLGSAVTDTVVGWLDAATSL (서열번호:1952)
*DDPKLYDKDLGSAVTDTVVGWMDAAWSL$ (서열번호:1953)
*DDPKLYDKDLGSAVTDTVVGWMDAAWSL (서열번호:1954)
*DDPKLYDKDLGSAVTDTVVGWMDAATSL$ (서열번호:1955)
*DDPKLYDKDLGSAVTDTVVGWMDAATSL (서열번호:1956)
*DDPKLYDKDLGSAVTDTVVGQVDAAWSL$ (서열번호:1957)
*DDPKLYDKDLGSAVTDTVVGQVDAAWSL (서열번호:1958)
*DDPKLYDKDLGSAVTDTVVGQVDAATSL$ (서열번호:1959)
*DDPKLYDKDLGSAVTDTVVGQVDAATSL (서열번호:I960)
*DDPKLYDKDLGSAVTDTVVGQLDAAWSL$ (서열번호:1961)
*DDPKLYDKDLGSAVTDTVVGQLDAAWSL (서열번호:1962)
*DDPKLYDKDLGSAVTDTVVGQLDAATSL$ (서열번호:1963)
*DDPKLYDKDLGSAVTDTVVGQLDAATSL (서열번호:1964)
*DDPKLYDKDLGSAVTDTVVGQMDAAWSL$ (서열번호:1965)
*DDPKLYDKDLGSAVTDTVVGQMDAAWSL (서열번호:1966)
*DDPKLYDKDLGSAVTDTVVGQMDAATSL$ (서열번호:1967)
*DDPKLYDKDLGSAVTDTVVGQMDAATSL (서열번호:1968)
*DDPKLYDKDLGSAVGDWVVAWVDAAWSL$ (서열번호:1969)
*DDPKLYDKDLGSAVGDWVVAWVDAAWSL (서열번호:1970)
*DDPKLYDKDLGSAVGDWVVAWVDAATSL$ (서열번호:1971)
*DDPKLYDKDLGSAVGDWVVAWVDAATSL (서열번호:1972)
*DDPKLYDKDLGSAVGDWVVAWLDAAWSL$ (서열번호:1973)
*DDPKLYDKDLGSAVGDWVVAWLDAAWSL (서열번호:1974)
*DDPKLYDKDLGSAVGDWVVAWLDAATSL$ (서열번호:1975)
*DDPKLYDKDLGSAVGDWVVAWLDAATSL (서열번호:1976)
*DDPKLYDKDLGSAVGDWVVAWMDAAWSL$ (서열번호:1977)
*DDPKLYDKDLGSAVGDWVVAWMDAAWSL (서열번호:1978)
*DDPKLYDKDLGSAVGDWVVAWMDAATSL$ (서열번호:1979)
*DDPKLYDKDLGSAVGDWVVAWMDAATSL (서열번호:1980)
*DDPKLYDKDLGSAVGDWVVAQVDAAWSL$ (서열번호:1981)
*DDPKLYDKDLGSAVGDWVVAQVDAAWSL (서열번호:1982)
*DDPKLYDKDLGSAVGDWVVAQVDAATSL$ (서열번호:1983)
*DDPKLYDKDLGSAVGDWVVAQVDAATSL (서열번호:1984)
*DDPKLYDKDLGSAVGDWVVAQLDAAWSL$ (서열번호:1985)
*DDPKLYDKDLGSAVGDWVVAQLDAAWSL (서열번호:1986)
*DDPKLYDKDLGSAVGDWVVAQLDAATSL$ (서열번호:1987)
*DDPKLYDKDLGSAVGDWVVAQLDAATSL (서열번호:1988)
*DDPKLYDKDLGSAVGDWVVAQMDAAWSL$ (서열번호:1989)
*DDPKLYDKDLGSAVGDWVVAQMDAAWSL (서열번호:1990)
*DDPKLYDKDLGSAVGDWVVAQMDAATSL$ (서열번호:1991)
*DDPKLYDKDLGSAVGDWVVAQMDAATSL (서열번호:1992)
*DDPKLYDKDLGSAVGDWVVGWVDAAWSL$ (서열번호:1993)
*DDPKLYDKDLGSAVGDWVVGWVDAAWSL (서열번호:1994)
*DDPKLYDKDLGSAVGDWVVGWVDAATSL$ (서열번호:1995)
*DDPKLYDKDLGSAVGDWVVGWVDAATSL (서열번호:1996)
*DDPKLYDKDLGSAVGDWVVGWLDAAWSL$ (서열번호:1997)
*DDPKLYDKDLGSAVGDWVVGWLDAAWSL (서열번호:1998)
*DDPKLYDKDLGSAVGDWVVGWLDAATSL$ (서열번호:1999)
*DDPKLYDKDLGSAVGDWVVGWLDAATSL (서열번호:2000)
*DDPKLYDKDLGSAVGDWVVGWMDAAWSL$ (서열번호:2001)
*DDPKLYDKDLGSAVGDWVVGWMDAAWSL (서열번호:2002)
*DDPKLYDKDLGSAVGDWVVGWMDAATSL$ (서열번호:2003)
*DDPKLYDKDLGSAVGDWVVGWMDAATSL (서열번호:2004)
*DDPKLYDKDLGSAVGDWVVGQVDAAWSL$ (서열번호:2005)
*DDPKLYDKDLGSAVGDWVVGQVDAAWSL (서열번호:2006)
*DDPKLYDKDLGSAVGDWVVGQVDAATSL$ (서열번호:2007)
*DDPKLYDKDLGSAVGDWVVGQVDAATSL (서열번호:2008)
*DDPKLYDKDLGSAVGDWVVGQLDAAWSL$ (서열번호:2009)
*DDPKLYDKDLGSAVGDWVVGQLDAAWSL (서열번호:2010)
*DDPKLYDKDLGSAVGDWVVGQLDAATSL$ (서열번호:2011)
*DDPKLYDKDLGSAVGDWVVGQLDAATSL (서열번호:2012)
*DDPKLYDKDLGSAVGDWVVGQMDAAWSL$ (서열번호:2013)
*DDPKLYDKDLGSAVGDWVVGQMDAAWSL (서열번호:2014)
*DDPKLYDKDLGSAVGDWVVGQMDAATSL$ (서열번호:2015)
*DDPKLYDKDLGSAVGDWVVGQMDAATSL (서열번호:2016)
*DDPKLYDKDLGSAVGDTVVAWVDAAWSL$ (서열번호:2017)
*DDPKLYDKDLGSAVGDTVVAWVDAAWSL (서열번호:2018)
*DDPKLYDKDLGSAVGDTVVAWVDAATSL$ (서열번호:2019)
*DDPKLYDKDLGSAVGDTVVAWVDAATSL (서열번호:2020)
*DDPKLYDKDLGSAVGDTVVAWLDAAWSL$ (서열번호:2021)
*DDPKLYDKDLGSAVGDTVVAWLDAAWSL (서열번호:2022)
*DDPKLYDKDLGSAVGDTVVAWLDAATSL$ (서열번호:2023)
*DDPKLYDKDLGSAVGDTVVAWLDAATSL (서열번호:2024)
*DDPKLYDKDLGSAVGDTVVAWMDAAWSL$ (서열번호:2025)
*DDPKLYDKDLGSAVGDTVVAWMDAAWSL (서열번호:2026)
*DDPKLYDKDLGSAVGDTVVAWMDAATSL$ (서열번호:2027)
*DDPKLYDKDLGSAVGDTVVAWMDAATSL (서열번호:2028)
*DDPKLYDKDLGSAVGDTVVAQVDAAWSL$ (서열번호:2029)
*DDPKLYDKDLGSAVGDTVVAQVDAAWSL (서열번호:2030)
*DDPKLYDKDLGSAVGDTVVAQVDAATSL$ (서열번호:2031)
*DDPKLYDKDLGSAVGDTVVAQVDAATSL (서열번호:2032)
*DDPKLYDKDLGSAVGDTVVAQLDAAWSL$ (서열번호:2033)
*DDPKLYDKDLGSAVGDTVVAQLDAAWSL (서열번호:2034)
*DDPKLYDKDLGSAVGDTVVAQLDAATSL$ (서열번호:2035)
*DDPKLYDKDLGSAVGDTVVAQLDAATSL (서열번호:2036)
*DDPKLYDKDLGSAVGDTVVAQMDAAWSL$ (서열번호:2037)
*DDPKLYDKDLGSAVGDTVVAQMDAAWSL (서열번호:2038)
*DDPKLYDKDLGSAVGDTVVAQMDAATSL$ (서열번호:2039)
*DDPKLYDKDLGSAVGDTVVAQMDAATSL (서열번호:2040)
*DDPKLYDKDLGSAVGDTVVGWVDAAWSL$ (서열번호:2041)
*DDPKLYDKDLGSAVGDTVVGWVDAAWSL (서열번호:2042)
*DDPKLYDKDLGSAVGDTVVGWVDAATSL$ (서열번호:2043)
*DDPKLYDKDLGSAVGDTVVGWVDAATSL (서열번호:2044)
*DDPKLYDKDLGSAVGDTVVGWLDAAWSL$ (서열번호:2045)
*DDPKLYDKDLGSAVGDTVVGWLDAAWSL (서열번호:2046)
*DDPKLYDKDLGSAVGDTVVGWLDAATSL$ (서열번호:2047)
*DDPKLYDKDLGSAVGDTVVGWLDAATSL (서열번호:2048)
*DDPKLYDKDLGSAVGDTVVGWMDAAWSL$ (서열번호:2049)
*DDPKLYDKDLGSAVGDTVVGWMDAAWSL (서열번호:2050)
*DDPKLYDKDLGSAVGDTVVGWMDAATSL$ (서열번호:2051)
*DDPKLYDKDLGSAVGDTVVGWMDAATSL (서열번호:2052)
*DDPKLYDKDLGSAVGDTVVGQVDAAWSL$ (서열번호:2053)
*DDPKLYDKDLGSAVGDTVVGQVDAAWSL (서열번호:2054)
*DDPKLYDKDLGSAVGDTVVGQVDAATSL$ (서열번호:2055)
*DDPKLYDKDLGSAVGDTVVGQVDAATSL (서열번호:2056)
*DDPKLYDKDLGSAVGDTVVGQLDAAWSL$ (서열번호:2057)
*DDPKLYDKDLGSAVGDTVVGQLDAAWSL (서열번호:2058)
*DDPKLYDKDLGSAVGDTVVGQLDAATSL$ (서열번호:2059)
*DDPKLYDKDLGSAVGDTVVGQLDAATSL (서열번호:2060)
*DDPKLYDKDLGSAVGDTVVGQMDAAWSL$ (서열번호:2061)
*DDPKLYDKDLGSAVGDTVVGQMDAAWSL (서열번호:2062)
*DDPKLYDKDLGSAVGDTVVGQMDAATSL$ (서열번호:2063)
*DDPKLYDKDLGSAVGDTVVGQMDAATSL (서열번호:2064)
*DDPKLYDKDLGSALWDWVVAWVDAAWSL$ (서열번호:2065)
*DDPKLYDKDLGSALWDWVVAWVDAAWSL (서열번호:2066)
*DDPKLYDKDLGSALWDWVVAWVDAATSL$ (서열번호:2067)
*DDPKLYDKDLGSALWDWVVAWVDAATSL (서열번호:2068)
*DDPKLYDKDLGSALWDWVVAWLDAAWSL$ (서열번호:2069)
*DDPKLYDKDLGSALWDWVVAWLDAAWSL (서열번호:2070)
*DDPKLYDKDLGSALWDWVVAWLDAATSL$ (서열번호:2071)
*DDPKLYDKDLGSALWDWVVAWLDAATSL (서열번호:2072)
*DDPKLYDKDLGSALWDWVVAWMDAAWSL$ (서열번호:2073)
*DDPKLYDKDLGSALWDWVVAWMDAAWSL (서열번호:2074)
*DDPKLYDKDLGSALWDWVVAWMDAATSL$ (서열번호:2075)
*DDPKLYDKDLGSALWDWVVAWMDAATSL (서열번호:2076)
*DDPKLYDKDLGSALWDWVVAQVDAAWSL$ (서열번호:2077)
*DDPKLYDKDLGSALWDWVVAQVDAAWSL (서열번호:2078)
*DDPKLYDKDLGSALWDWVVAQVDAATSL$ (서열번호:2079)
*DDPKLYDKDLGSALWDWVVAQVDAATSL (서열번호:2080)
*DDPKLYDKDLGSALWDWVVAQLDAAWSL$ (서열번호:2081)
*DDPKLYDKDLGSALWDWVVAQLDAAWSL (서열번호:2082)
*DDPKLYDKDLGSALWDWVVAQLDAATSL$ (서열번호:2083)
*DDPKLYDKDLGSALWDWVVAQLDAATSL (서열번호:2084)
*DDPKLYDKDLGSALWDWVVAQMDAAWSL$ (서열번호:2085)
*DDPKLYDKDLGSALWDWVVAQMDAAWSL (서열번호:2086)
*DDPKLYDKDLGSALWDWVVAQMDAATSL$ (서열번호:2087)
*DDPKLYDKDLGSALWDWVVAQMDAATSL (서열번호:2088)
*DDPKLYDKDLGSALWDWVVGWVDAAWSL$ (서열번호:2089)
*DDPKLYDKDLGSALWDWVVGWVDAAWSL (서열번호:2090)
*DDPKLYDKDLGSALWDWVVGWVDAATSL$ (서열번호:2091)
*DDPKLYDKDLGSALWDWVVGWVDAATSL (서열번호:2092)
*DDPKLYDKDLGSALWDWVVGWLDAAWSL$ (서열번호:2093)
*DDPKLYDKDLGSALWDWVVGWLDAAWSL (서열번호:2094)
*DDPKLYDKDLGSALWDWVVGWLDAATSL$ (서열번호:2095)
*DDPKLYDKDLGSALWDWVVGWLDAATSL (서열번호:2096)
*DDPKLYDKDLGSALWDWVVGWMDAAWSL$ (서열번호:2097)
*DDPKLYDKDLGSALWDWVVGWMDAAWSL (서열번호:2098)
*DDPKLYDKDLGSALWDWVVGWMDAATSL$ (서열번호:2099)
*DDPKLYDKDLGSALWDWVVGWMDAATSL (서열번호:2100)
*DDPKLYDKDLGSALWDWVVGQVDAAWSL$ (서열번호:2101)
*DDPKLYDKDLGSALWDWVVGQVDAAWSL (서열번호:2102)
*DDPKLYDKDLGSALWDWVVGQVDAATSL$ (서열번호:2103)
*DDPKLYDKDLGSALWDWVVGQVDAATSL (서열번호:2104)
*DDPKLYDKDLGSALWDWVVGQLDAAWSL$ (서열번호:2105)
*DDPKLYDKDLGSALWDWVVGQLDAAWSL (서열번호:2106)
*DDPKLYDKDLGSALWDWVVGQLDAATSL$ (서열번호:2107)
*DDPKLYDKDLGSALWDWVVGQLDAATSL (서열번호:2108)
*DDPKLYDKDLGSALWDWVVGQMDAAWSL$ (서열번호:2109)
*DDPKLYDKDLGSALWDWVVGQMDAAWSL (서열번호:2110)
*DDPKLYDKDLGSALWDWVVGQMDAATSL$ (서열번호:2111)
*DDPKLYDKDLGSALWDWVVGQMDAATSL (서열번호:2112)
*DDPKLYDKDLGSALWDTVVAWVDAAWSL$ (서열번호:2113)
*DDPKLYDKDLGSALWDTVVAWVDAAWSL (서열번호:2114)
*DDPKLYDKDLGSALWDTVVAWVDAATSL$ (서열번호:2115)
*DDPKLYDKDLGSALWDTVVAWVDAATSL (서열번호:2116)
*DDPKLYDKDLGSALWDTVVAWLDAAWSL$ (서열번호:2117)
*DDPKLYDKDLGSALWDTVVAWLDAAWSL (서열번호:2118)
*DDPKLYDKDLGSALWDTVVAWLDAATSL$ (서열번호:2119)
*DDPKLYDKDLGSALWDTVVAWLDAATSL (서열번호:2120)
*DDPKLYDKDLGSALWDTVVAWMDAAWSL$ (서열번호:2121)
*DDPKLYDKDLGSALWDTVVAWMDAAWSL (서열번호:2122)
*DDPKLYDKDLGSALWDTVVAWMDAATSL$ (서열번호:2123)
*DDPKLYDKDLGSALWDTVVAWMDAATSL (서열번호:2124)
*DDPKLYDKDLGSALWDTVVAQVDAAWSL$ (서열번호:2125)
*DDPKLYDKDLGSALWDTVVAQVDAAWSL (서열번호:2126)
*DDPKLYDKDLGSALWDTVVAQVDAATSL$ (서열번호:2127)
*DDPKLYDKDLGSALWDTVVAQVDAATSL (서열번호:2128)
*DDPKLYDKDLGSALWDTVVAQLDAAWSL$ (서열번호:2129)
*DDPKLYDKDLGSALWDTVVAQLDAAWSL (서열번호:2130)
*DDPKLYDKDLGSALWDTVVAQLDAATSL$ (서열번호:2131)
*DDPKLYDKDLGSALWDTVVAQLDAATSL (서열번호:2132)
*DDPKLYDKDLGSALWDTVVAQMDAAWSL$ (서열번호:2133)
*DDPKLYDKDLGSALWDTVVAQMDAAWSL (서열번호:2134)
*DDPKLYDKDLGSALWDTVVAQMDAATSL$ (서열번호:2135)
*DDPKLYDKDLGSALWDTVVAQMDAATSL (서열번호:2136)
*DDPKLYDKDLGSALWDTVVGWVDAAWSL$ (서열번호:2137)
*DDPKLYDKDLGSALWDTVVGWVDAAWSL (서열번호:2138)
*DDPKLYDKDLGSALWDTVVGWVDAATSL$ (서열번호:2139)
*DDPKLYDKDLGSALWDTVVGWVDAATSL (서열번호:2140)
*DDPKLYDKDLGSALWDTVVGWLDAAWSL$ (서열번호:2141)
*DDPKLYDKDLGSALWDTVVGWLDAAWSL (서열번호:2142)
*DDPKLYDKDLGSALWDTVVGWLDAATSL$ (서열번호:2143)
*DDPKLYDKDLGSALWDTVVGWLDAATSL (서열번호:2144)
*DDPKLYDKDLGSALWDTVVGWMDAAWSL$ (서열번호:2145)
*DDPKLYDKDLGSALWDTVVGWMDAAWSL (서열번호:2146)
*DDPKLYDKDLGSALWDTVVGWMDAATSL$ (서열번호:2147)
*DDPKLYDKDLGSALWDTVVGWMDAATSL (서열번호:2148)
*DDPKLYDKDLGSALWDTVVGQVDAAWSL$ (서열번호:2149)
*DDPKLYDKDLGSALWDTVVGQVDAAWSL (서열번호:2150)
*DDPKLYDKDLGSALWDTVVGQVDAATSL$ (서열번호:2151)
*DDPKLYDKDLGSALWDTVVGQVDAATSL (서열번호:2152)
*DDPKLYDKDLGSALWDTVVGQLDAAWSL$ (서열번호:2153)
*DDPKLYDKDLGSALWDTVVGQLDAAWSL (서열번호:2154)
*DDPKLYDKDLGSALWDTVVGQLDAATSL$ (서열번호:2155)
*DDPKLYDKDLGSALWDTVVGQLDAATSL (서열번호:2156)
*DDPKLYDKDLGSALWDTVVGQMDAAWSL$ (서열번호:2157)
*DDPKLYDKDLGSALWDTVVGQMDAAWSL (서열번호:2158)
*DDPKLYDKDLGSALWDTVVGQMDAATSL$ (서열번호:2159)
*DDPKLYDKDLGSALWDTVVGQMDAATSL (서열번호:2160)
*DDPKLYDKDLGSALTDWVVAWVDAAWSL$ (서열번호:2161)
*DDPKLYDKDLGSALTDWVVAWVDAAWSL (서열번호:2162)
*DDPKLYDKDLGSALTDWVVAWVDAATSL$ (서열번호:2163)
*DDPKLYDKDLGSALTDWVVAWVDAATSL (서열번호:2164)
*DDPKLYDKDLGSALTDWVVAWLDAAWSL$ (서열번호:2165)
*DDPKLYDKDLGSALTDWVVAWLDAAWSL (서열번호:2166)
*DDPKLYDKDLGSALTDWVVAWLDAATSL$ (서열번호:2167)
*DDPKLYDKDLGSALTDWVVAWLDAATSL (서열번호:2168)
*DDPKLYDKDLGSALTDWVVAWMDAAWSL$ (서열번호:2169)
*DDPKLYDKDLGSALTDWVVAWMDAAWSL (서열번호:2170)
*DDPKLYDKDLGSALTDWVVAWMDAATSL$ (서열번호:2171)
*DDPKLYDKDLGSALTDWVVAWMDAATSL (서열번호:2172)
*DDPKLYDKDLGSALTDWVVAQVDAAWSL$ (서열번호:2173)
*DDPKLYDKDLGSALTDWVVAQVDAAWSL (서열번호:2174)
*DDPKLYDKDLGSALTDWVVAQVDAATSL$ (서열번호:2175)
*DDPKLYDKDLGSALTDWVVAQVDAATSL (서열번호:2176)
*DDPKLYDKDLGSALTDWVVAQLDAAWSL$ (서열번호:2177)
*DDPKLYDKDLGSALTDWVVAQLDAAWSL (서열번호:2178)
*DDPKLYDKDLGSALTDWVVAQLDAATSL$ (서열번호:2179)
*DDPKLYDKDLGSALTDWVVAQLDAATSL (서열번호:2180)
*DDPKLYDKDLGSALTDWVVAQMDAAWSL$ (서열번호:2181)
*DDPKLYDKDLGSALTDWVVAQMDAAWSL (서열번호:2182)
*DDPKLYDKDLGSALTDWVVAQMDAATSL$ (서열번호:2183)
*DDPKLYDKDLGSALTDWVVAQMDAATSL (서열번호:2184)
*DDPKLYDKDLGSALTDWVVGWVDAAWSL$ (서열번호:2185)
*DDPKLYDKDLGSALTDWVVGWVDAAWSL (서열번호:2186)
*DDPKLYDKDLGSALTDWVVGWVDAATSL$ (서열번호:2187)
*DDPKLYDKDLGSALTDWVVGWVDAATSL (서열번호:2188)
*DDPKLYDKDLGSALTDWVVGWLDAAWSL$ (서열번호:2189)
*DDPKLYDKDLGSALTDWVVGWLDAAWSL (서열번호:2190)
*DDPKLYDKDLGSALTDWVVGWLDAATSL$ (서열번호:2191)
*DDPKLYDKDLGSALTDWVVGWLDAATSL (서열번호:2192)
*DDPKLYDKDLGSALTDWVVGWMDAAWSL$ (서열번호:2193)
*DDPKLYDKDLGSALTDWVVGWMDAAWSL (서열번호:2194)
*DDPKLYDKDLGSALTDWVVGWMDAATSL$ (서열번호:2195)
*DDPKLYDKDLGSALTDWVVGWMDAATSL (서열번호:2196)
*DDPKLYDKDLGSALTDWVVGQVDAAWSL$ (서열번호:2197)
*DDPKLYDKDLGSALTDWVVGQVDAAWSL (서열번호:2198)
*DDPKLYDKDLGSALTDWVVGQVDAATSL$ (서열번호:2199)
*DDPKLYDKDLGSALTDWVVGQVDAATSL (서열번호:2200)
*DDPKLYDKDLGSALTDWVVGQLDAAWSL$ (서열번호:2201)
*DDPKLYDKDLGSALTDWVVGQLDAAWSL (서열번호:2202)
*DDPKLYDKDLGSALTDWVVGQLDAATSL$ (서열번호:2203)
*DDPKLYDKDLGSALTDWVVGQLDAATSL (서열번호:2204)
*DDPKLYDKDLGSALTDWVVGQMDAAWSL$ (서열번호:2205)
*DDPKLYDKDLGSALTDWVVGQMDAAWSL (서열번호:2206)
*DDPKLYDKDLGSALTDWVVGQMDAATSL$ (서열번호:2207)
*DDPKLYDKDLGSALTDWVVGQMDAATSL (서열번호:2208)
*DDPKLYDKDLGSALTDTVVAWVDAAWSL$ (서열번호:2209)
*DDPKLYDKDLGSALTDTVVAWVDAAWSL (서열번호:2210)
*DDPKLYDKDLGSALTDTVVAWVDAATSL$ (서열번호:2211)
*DDPKLYDKDLGSALTDTVVAWVDAATSL (서열번호:2212)
*DDPKLYDKDLGSALTDTVVAWLDAAWSL$ (서열번호:2213)
*DDPKLYDKDLGSALTDTVVAWLDAAWSL (서열번호:2214)
*DDPKLYDKDLGSALTDTVVAWLDAATSL$ (서열번호:2215)
*DDPKLYDKDLGSALTDTVVAWLDAATSL (서열번호:2216)
*DDPKLYDKDLGSALTDTVVAWMDAAWSL$ (서열번호:2217)
*DDPKLYDKDLGSALTDTVVAWMDAAWSL (서열번호:2218)
*DDPKLYDKDLGSALTDTVVAWMDAATSL$ (서열번호:2219)
*DDPKLYDKDLGSALTDTVVAWMDAATSL (서열번호:2220)
*DDPKLYDKDLGSALTDTVVAQVDAAWSL$ (서열번호:2221)
*DDPKLYDKDLGSALTDTVVAQVDAAWSL (서열번호:2222)
*DDPKLYDKDLGSALTDTVVAQVDAATSL$ (서열번호:2223)
*DDPKLYDKDLGSALTDTVVAQVDAATSL (서열번호:2224)
*DDPKLYDKDLGSALTDTVVAQLDAAWSL$ (서열번호:2225)
*DDPKLYDKDLGSALTDTVVAQLDAAWSL (서열번호:2226)
*DDPKLYDKDLGSALTDTVVAQLDAATSL$ (서열번호:2227)
*DDPKLYDKDLGSALTDTVVAQLDAATSL (서열번호:2228)
*DDPKLYDKDLGSALTDTVVAQMDAAWSL$ (서열번호:2229)
*DDPKLYDKDLGSALTDTVVAQMDAAWSL (서열번호:2230)
*DDPKLYDKDLGSALTDTVVAQMDAATSL$ (서열번호:2231)
*DDPKLYDKDLGSALTDTVVAQMDAATSL (서열번호:2232)
*DDPKLYDKDLGSALTDTVVGWVDAAWSL$ (서열번호:2233)
*DDPKLYDKDLGSALTDTVVGWVDAAWSL (서열번호:2234)
*DDPKLYDKDLGSALTDTVVGWVDAATSL$ (서열번호:2235)
*DDPKLYDKDLGSALTDTVVGWVDAATSL (서열번호:2236)
*DDPKLYDKDLGSALTDTVVGWLDAAWSL$ (서열번호:2237)
*DDPKLYDKDLGSALTDTVVGWLDAAWSL (서열번호:2238)
*DDPKLYDKDLGSALTDTVVGWLDAATSL$ (서열번호:2239)
*DDPKLYDKDLGSALTDTVVGWLDAATSL (서열번호:2240)
*DDPKLYDKDLGSALTDTVVGWMDAAWSL$ (서열번호:2241)
*DDPKLYDKDLGSALTDTVVGWMDAAWSL (서열번호:2242)
*DDPKLYDKDLGSALTDTVVGWMDAATSL$ (서열번호:2243)
*DDPKLYDKDLGSALTDTVVGWMDAATSL (서열번호:2244)
*DDPKLYDKDLGSALTDTVVGQVDAAWSL$ (서열번호:2245)
*DDPKLYDKDLGSALTDTVVGQVDAAWSL (서열번호:2246)
*DDPKLYDKDLGSALTDTVVGQVDAATSL$ (서열번호:2247)
*DDPKLYDKDLGSALTDTVVGQVDAATSL (서열번호:2248)
*DDPKLYDKDLGSALTDTVVGQLDAAWSL$ (서열번호:2249)
*DDPKLYDKDLGSALTDTVVGQLDAAWSL (서열번호:2250)
*DDPKLYDKDLGSALTDTVVGQLDAATSL$ (서열번호:2251)
*DDPKLYDKDLGSALTDTVVGQLDAATSL (서열번호:2252)
*DDPKLYDKDLGSALTDTVVGQMDAAWSL$ (서열번호:2253)
*DDPKLYDKDLGSALTDTVVGQMDAAWSL (서열번호:2254)
*DDPKLYDKDLGSALTDTVVGQMDAATSL$ (서열번호:2255)
*DDPKLYDKDLGSALTDTVVGQMDAATSL (서열번호:2256)
*DDPKLYDKDLGSALGDWVVAWVDAAWSL$ (서열번호:2257)
*DDPKLYDKDLGSALGDWVVAWVDAAWSL (서열번호:2258)
*DDPKLYDKDLGSALGDWVVAWVDAATSL$ (서열번호:2259)
*DDPKLYDKDLGSALGDWVVAWVDAATSL (서열번호:2260)
*DDPKLYDKDLGSALGDWVVAWLDAAWSL$ (서열번호:2261)
*DDPKLYDKDLGSALGDWVVAWLDAAWSL (서열번호:2262)
*DDPKLYDKDLGSALGDWVVAWLDAATSL$ (서열번호:2263)
*DDPKLYDKDLGSALGDWVVAWLDAATSL (서열번호:2264)
*DDPKLYDKDLGSALGDWVVAWMDAAWSL$ (서열번호:2265)
*DDPKLYDKDLGSALGDWVVAWMDAAWSL (서열번호:2266)
*DDPKLYDKDLGSALGDWVVAWMDAATSL$ (서열번호:2267)
*DDPKLYDKDLGSALGDWVVAWMDAATSL (서열번호:2268)
*DDPKLYDKDLGSALGDWVVAQVDAAWSL$ (서열번호:2269)
*DDPKLYDKDLGSALGDWVVAQVDAAWSL (서열번호:2270)
*DDPKLYDKDLGSALGDWVVAQVDAATSL$ (서열번호:2271)
*DDPKLYDKDLGSALGDWVVAQVDAATSL (서열번호:2272)
*DDPKLYDKDLGSALGDWVVAQLDAAWSL$ (서열번호:2273)
*DDPKLYDKDLGSALGDWVVAQLDAAWSL (서열번호:2274)
*DDPKLYDKDLGSALGDWVVAQLDAATSL$ (서열번호:2275)
*DDPKLYDKDLGSALGDWVVAQLDAATSL (서열번호:2276)
*DDPKLYDKDLGSALGDWVVAQMDAAWSL$ (서열번호:2277)
*DDPKLYDKDLGSALGDWVVAQMDAAWSL (서열번호:2278)
*DDPKLYDKDLGSALGDWVVAQMDAATSL$ (서열번호:2279)
*DDPKLYDKDLGSALGDWVVAQMDAATSL (서열번호:2280)
*DDPKLYDKDLGSALGDWVVGWVDAAWSL$ (서열번호:2281)
*DDPKLYDKDLGSALGDWVVGWVDAAWSL (서열번호:2282)
*DDPKLYDKDLGSALGDWVVGWVDAATSL$ (서열번호:2283)
*DDPKLYDKDLGSALGDWVVGWVDAATSL (서열번호:2284)
*DDPKLYDKDLGSALGDWVVGWLDAAWSL$ (서열번호:2285)
*DDPKLYDKDLGSALGDWVVGWLDAAWSL (서열번호:2286)
*DDPKLYDKDLGSALGDWVVGWLDAATSL$ (서열번호:2287)
*DDPKLYDKDLGSALGDWVVGWLDAATSL (서열번호:2288)
*DDPKLYDKDLGSALGDWVVGWMDAAWSL$ (서열번호:2289)
*DDPKLYDKDLGSALGDWVVGWMDAAWSL (서열번호:2290)
*DDPKLYDKDLGSALGDWVVGWMDAATSL$ (서열번호:2291)
*DDPKLYDKDLGSALGDWVVGWMDAATSL (서열번호:2292)
*DDPKLYDKDLGSALGDWVVGQVDAAWSL$ (서열번호:2293)
*DDPKLYDKDLGSALGDWVVGQVDAAWSL (서열번호:2294)
*DDPKLYDKDLGSALGDWVVGQVDAATSL$ (서열번호:2295)
*DDPKLYDKDLGSALGDWVVGQVDAATSL (서열번호:2296)
*DDPKLYDKDLGSALGDWVVGQLDAAWSL$ (서열번호:2297)
*DDPKLYDKDLGSALGDWVVGQLDAAWSL (서열번호:2298)
*DDPKLYDKDLGSALGDWVVGQLDAATSL$ (서열번호:2299)
*DDPKLYDKDLGSALGDWVVGQLDAATSL (서열번호:2300)
*DDPKLYDKDLGSALGDWVVGQMDAAWSL$ (서열번호:2301)
*DDPKLYDKDLGSALGDWVVGQMDAAWSL (서열번호:2302)
*DDPKLYDKDLGSALGDWVVGQMDAATSL$ (서열번호:2303)
*DDPKLYDKDLGSALGDWVVGQMDAATSL (서열번호:2304)
*DDPKLYDKDLGSALGDTVVAWVDAAWSL$ (서열번호:2305)
*DDPKLYDKDLGSALGDTVVAWVDAAWSL (서열번호:2306)
*DDPKLYDKDLGSALGDTVVAWVDAATSL$ (서열번호:2307)
*DDPKLYDKDLGSALGDTVVAWVDAATSL (서열번호:2308)
*DDPKLYDKDLGSALGDTVVAWLDAAWSL$ (서열번호:2309)
*DDPKLYDKDLGSALGDTVVAWLDAAWSL (서열번호:2310)
*DDPKLYDKDLGSALGDTVVAWLDAATSL$ (서열번호:2311)
*DDPKLYDKDLGSALGDTVVAWLDAATSL (서열번호:2312)
*DDPKLYDKDLGSALGDTVVAWMDAAWSL$ (서열번호:2313)
*DDPKLYDKDLGSALGDTVVAWMDAAWSL (서열번호:2314)
*DDPKLYDKDLGSALGDTVVAWMDAATSL$ (서열번호:2315)
*DDPKLYDKDLGSALGDTVVAWMDAATSL (서열번호:2316)
*DDPKLYDKDLGSALGDTVVAQVDAAWSL$ (서열번호:2317)
*DDPKLYDKDLGSALGDTVVAQVDAAWSL (서열번호:2318)
*DDPKLYDKDLGSALGDTVVAQVDAATSL$ (서열번호:2319)
*DDPKLYDKDLGSALGDTVVAQVDAATSL (서열번호:2320)
*DDPKLYDKDLGSALGDTVVAQLDAAWSL$ (서열번호:2321)
*DDPKLYDKDLGSALGDTVVAQLDAAWSL (서열번호:2322)
*DDPKLYDKDLGSALGDTVVAQLDAATSL$ (서열번호:2323)
*DDPKLYDKDLGSALGDTVVAQLDAATSL (서열번호:2324)
*DDPKLYDKDLGSALGDTVVAQMDAAWSL$ (서열번호:2325)
*DDPKLYDKDLGSALGDTVVAQMDAAWSL (서열번호:2326)
*DDPKLYDKDLGSALGDTVVAQMDAATSL$ (서열번호:2327)
*DDPKLYDKDLGSALGDTVVAQMDAATSL (서열번호:2328)
*DDPKLYDKDLGSALGDTVVGWVDAAWSL$ (서열번호:2329)
*DDPKLYDKDLGSALGDTVVGWVDAAWSL (서열번호:2330)
*DDPKLYDKDLGSALGDTVVGWVDAATSL$ (서열번호:2331)
*DDPKLYDKDLGSALGDTVVGWVDAATSL (서열번호:2332)
*DDPKLYDKDLGSALGDTVVGWLDAAWSL$ (서열번호:2333)
*DDPKLYDKDLGSALGDTVVGWLDAAWSL (서열번호:2334)
*DDPKLYDKDLGSALGDTVVGWLDAATSL$ (서열번호:2335)
*DDPKLYDKDLGSALGDTVVGWLDAATSL (서열번호:2336)
*DDPKLYDKDLGSALGDTVVGWMDAAWSL$ (서열번호:2337)
*DDPKLYDKDLGSALGDTVVGWMDAAWSL (서열번호:2338)
*DDPKLYDKDLGSALGDTVVGWMDAATSL$ (서열번호:2339)
*DDPKLYDKDLGSALGDTVVGWMDAATSL (서열번호:2340)
*DDPKLYDKDLGSALGDTVVGQVDAAWSL$ (서열번호:2341)
*DDPKLYDKDLGSALGDTVVGQVDAAWSL (서열번호:2342)
*DDPKLYDKDLGSALGDTVVGQVDAATSL$ (서열번호:2343)
*DDPKLYDKDLGSALGDTVVGQVDAATSL (서열번호:2344)
*DDPKLYDKDLGSALGDTVVGQLDAAWSL$ (서열번호:2345)
*DDPKLYDKDLGSALGDTVVGQLDAAWSL (서열번호:2346)
*DDPKLYDKDLGSALGDTVVGQLDAATSL$ (서열번호:2347)
*DDPKLYDKDLGSALGDTVVGQLDAATSL (서열번호:2348)
*DDPKLYDKDLGSALGDTVVGQMDAAWSL$ (서열번호:2349)
*DDPKLYDKDLGSALGDTVVGQMDAAWSL (서열번호:2350)
*DDPKLYDKDLGSALGDTVVGQMDAATSL$ (서열번호:2351)
*DDPKLYDKDLGSALGDTVVGQMDAATSL (서열번호:2352)
*DDPKLYDKDLGSAMWDWVVAWVDAAWSL$ (서열번호:2353)
*DDPKLYDKDLGSAMWDWVVAWVDAAWSL (서열번호:2354)
*DDPKLYDKDLGSAMWDWVVAWVDAATSL$ (서열번호:2355)
*DDPKLYDKDLGSAMWDWVVAWVDAATSL (서열번호:2356)
*DDPKLYDKDLGSAMWDWVVAWLDAAWSL$ (서열번호:2357)
*DDPKLYDKDLGSAMWDWVVAWLDAAWSL (서열번호:2358)
*DDPKLYDKDLGSAMWDWVVAWLDAATSL$ (서열번호:2359)
*DDPKLYDKDLGSAMWDWVVAWLDAATSL (서열번호:2360)
*DDPKLYDKDLGSAMWDWVVAWMDAAWSL$ (서열번호:2361)
*DDPKLYDKDLGSAMWDWVVAWMDAAWSL (서열번호:2362)
*DDPKLYDKDLGSAMWDWVVAWMDAATSL$ (서열번호:2363)
*DDPKLYDKDLGSAMWDWVVAWMDAATSL (서열번호:2364)
*DDPKLYDKDLGSAMWDWVVAQVDAAWSL$ (서열번호:2365)
*DDPKLYDKDLGSAMWDWVVAQVDAAWSL (서열번호:2366)
*DDPKLYDKDLGSAMWDWVVAQVDAATSL$ (서열번호:2367)
*DDPKLYDKDLGSAMWDWVVAQVDAATSL (서열번호:2368)
*DDPKLYDKDLGSAMWDWVVAQLDAAWSL$ (서열번호:2369)
*DDPKLYDKDLGSAMWDWVVAQLDAAWSL (서열번호:2370)
*DDPKLYDKDLGSAMWDWVVAQLDAATSL$ (서열번호:2371)
*DDPKLYDKDLGSAMWDWVVAQLDAATSL (서열번호:2372)
*DDPKLYDKDLGSAMWDWVVAQMDAAWSL$ (서열번호:2373)
*DDPKLYDKDLGSAMWDWVVAQMDAAWSL (서열번호:2374)
*DDPKLYDKDLGSAMWDWVVAQMDAATSL$ (서열번호:2375)
*DDPKLYDKDLGSAMWDWVVAQMDAATSL (서열번호:2376)
*DDPKLYDKDLGSAMWDWVVGWVDAAWSL$ (서열번호:2377)
*DDPKLYDKDLGSAMWDWVVGWVDAAWSL (서열번호:2378)
*DDPKLYDKDLGSAMWDWVVGWVDAATSL$ (서열번호:2379)
*DDPKLYDKDLGSAMWDWVVGWVDAATSL (서열번호:2380)
*DDPKLYDKDLGSAMWDWVVGWLDAAWSL$ (서열번호:2381)
*DDPKLYDKDLGSAMWDWVGGWLDAAWSL (서열번호:2382)
*DDPKLYDKDLGSAMWDWVVGWLDAATSL$ (서열번호:2383)
*DDPKLYDKDLGSAMWDWVVGWLDAATSL (서열번호:2384)
*DDPKLYDKDLGSAMWDWVVGWMDAAWSL$ (서열번호:2385)
*DDPKLYDKDLGSAMWDWVVGWMDAAWSL (서열번호:2386)
*DDPKLYDKDLGSAMWDWVVGWMDAATSL$ (서열번호:2387)
*DDPKLYDKDLGSAMWDWVVGWMDAATSL (서열번호:2388)
*DDPKLYDKDLGSAMWDWVVGQVDAAWSL$ (서열번호:2389)
*DDPKLYDKDLGSAMWDWVVGQVDAAWSL (서열번호:2390)
*DDPKLYDKDLGSAMWDWVVGQVDAATSL$ (서열번호:2391)
*DDPKLYDKDLGSAMWDWVVGQVDAATSL (서열번호:2392)
*DDPKLYDKDLGSAMWDWVVGQLDAAWSL$ (서열번호:2393)
*DDPKLYDKDLGSAMWDWVVGQLDAAWSL (서열번호:2394)
*DDPKLYDKDLGSAMWDWVVGQLDAATSL$ (서열번호:2395)
*DDPKLYDKDLGSAMWDWVVGQLDAATSL (서열번호:2396)
*DDPKLYDKDLGSAMWDWVVGQMDAAWSL$ (서열번호:2397)
*DDPKLYDKDLGSAMWDWVVGQMDAAWSL (서열번호:2398)
*DDPKLYDKDLGSAMWDWVVGQMDAATSL$ (서열번호:2399)
*DDPKLYDKDLGSAMWDWVVGQMDAATSL (서열번호:2400)
*DDPKLYDKDLGSAMWDTVVAWVDAAWSL$ (서열번호:2401)
*DDPKLYDKDLGSAMWDTVVAWVDAAWSL (서열번호:2402)
*DDPKLYDKDLGSAMWDTVVAWVDAATSL$ (서열번호:2403)
*DDPKLYDKDLGSAMWDTVVAWVDAATSL (서열번호:2404)
*DDPKLYDKDLGSAMWDTVVAWLDAAWSL$ (서열번호:2405)
*DDPKLYDKDLGSAMWDTVVAWLDAAWSL (서열번호:2406)
*DDPKLYDKDLGSAMWDTVVAWLDAATSL$ (서열번호:2407)
*DDPKLYDKDLGSAMWDTVVAWLDAATSL (서열번호:2408)
*DDPKLYDKDLGSAMWDTVVAWMDAAWSL$ (서열번호:2409)
*DDPKLYDKDLGSAMWDTVVAWMDAAWSL (서열번호:2410)
*DDPKLYDKDLGSAMWDTVVAWMDAATSL$ (서열번호:2411)
*DDPKLYDKDLGSAMWDTVVAWMDAATSL (서열번호:2412)
*DDPKLYDKDLGSAMWDTVVAQVDAAWSL$ (서열번호:2413)
*DDPKLYDKDLGSAMWDTVVAQVDAAWSL (서열번호:2414)
*DDPKLYDKDLGSAMWDTVVAQVDAATSL$ (서열번호:2415)
*DDPKLYDKDLGSAMWDTVVAQVDAATSL (서열번호:2416)
*DDPKLYDKDLGSAMWDTVVAQLDAAWSL$ (서열번호:2417)
*DDPKLYDKDLGSAMWDTVVAQLDAAWSL (서열번호:2418)
*DDPKLYDKDLGSAMWDTVVAQLDAATSL$ (서열번호:2419)
*DDPKLYDKDLGSAMWDTVVAQLDAATSL (서열번호:2420)
*DDPKLYDKDLGSAMWDTVVAQMDAAWSL$ (서열번호:2421)
*DDPKLYDKDLGSAMWDTVVAQMDAAWSL (서열번호:2422)
*DDPKLYDKDLGSAMWDTVVAQMDAATSL$ (서열번호:2423)
*DDPKLYDKDLGSAMWDTVVAQMDAATSL (서열번호:2424)
*DDPKLYDKDLGSAMWDTVVGWVDAAWSL$ (서열번호:2425)
*DDPKLYDKDLGSAMWDTVVGWVDAAWSL (서열번호:2426)
*DDPKLYDKDLGSAMWDTVVGWVDAATSL$ (서열번호:2427)
*DDPKLYDKDLGSAMWDTVVGWVDAATSL (서열번호:2428)
*DDPKLYDKDLGSAMWDTVVGWLDAAWSL$ (서열번호:2429)
*DDPKLYDKDLGSAMWDTVVGWLDAAWSL (서열번호:2430)
*DDPKLYDKDLGSAMWDTVVGWLDAATSL$ (서열번호:2431)
*DDPKLYDKDLGSAMWDTVVGWLDAATSL (서열번호:2432)
*DDPKLYDKDLGSAMWDTVVGWMDAAWSL$ (서열번호:2433)
*DDPKLYDKDLGSAMWDTVVGWMDAAWSL (서열번호:2434)
*DDPKLYDKDLGSAMWDTVVGWMDAATSL$ (서열번호:2435)
*DDPKLYDKDLGSAMWDTVVGWMDAATSL (서열번호:2436)
*DDPKLYDKDLGSAMWDTVVGQVDAAWSL$ (서열번호:2437)
*DDPKLYDKDLGSAMWDTVVGQVDAAWSL (서열번호:2438)
*DDPKLYDKDLGSAMWDTVVGQVDAATSL$ (서열번호:2439)
*DDPKLYDKDLGSAMWDTVVGQVDAATSL (서열번호:2440)
*DDPKLYDKDLGSAMWDTVVGQLDAAWSL$ (서열번호:2441)
*DDPKLYDKDLGSAMWDTVVGQLDAAWSL (서열번호:2442)
*DDPKLYDKDLGSAMWDTVVGQLDAATSL$ (서열번호:2443)
*DDPKLYDKDLGSAMWDTVVGQLDAATSL (서열번호:2444)
*DDPKLYDKDLGSAMWDTVVGQMDAAWSL$ (서열번호:2445)
*DDPKLYDKDLGSAMWDTVVGQMDAAWSL (서열번호:2446)
*DDPKLYDKDLGSAMWDTVVGQMDAATSL$ (서열번호:2447)
*DDPKLYDKDLGSAMWDTVVGQMDAATSL (서열번호:2448)
*DDPKLYDKDLGSAMTDWVVAWVDAAWSL$ (서열번호:2449)
*DDPKLYDKDLGSAMTDWVVAWVDAAWSL (서열번호:2450)
*DDPKLYDKDLGSAMTDWVVAWVDAATSL$ (서열번호:2451)
*DDPKLYDKDLGSAMTDWVVAWVDAATSL (서열번호:2452)
*DDPKLYDKDLGSAMTDWVVAWLDAAWSL$ (서열번호:2453)
*DDPKLYDKDLGSAMTDWVVAWLDAAWSL (서열번호:2454)
*DDPKLYDKDLGSAMTDWVVAWLDAATSL$ (서열번호:2455)
*DDPKLYDKDLGSAMTDWVVAWLDAATSL (서열번호:2456)
*DDPKLYDKDLGSAMTDWVVAWMDAAWSL$ (서열번호:2457)
*DDPKLYDKDLGSAMTDWVVAWMDAAWSL (서열번호:2458)
*DDPKLYDKDLGSAMTDWVVAWMDAATSL$ (서열번호:2459)
*DDPKLYDKDLGSAMTDWVVAWMDAATSL (서열번호:2460)
*DDPKLYDKDLGSAMTDWVVAQVDAAWSL$ (서열번호:2461)
*DDPKLYDKDLGSAMTDWVVAQVDAAWSL (서열번호:2462)
*DDPKLYDKDLGSAMTDWVVAQVDAATSL$ (서열번호:2463)
*DDPKLYDKDLGSAMTDWVVAQVDAATSL (서열번호:2464)
*DDPKLYDKDLGSAMTDWVVAQLDAAWSL$ (서열번호:2465)
*DDPKLYDKDLGSAMTDWVVAQLDAAWSL (서열번호:2466)
*DDPKLYDKDLGSAMTDWVVAQLDAATSL$ (서열번호:2467)
*DDPKLYDKDLGSAMTDWVVAQLDAATSL (서열번호:2468)
*DDPKLYDKDLGSAMTDWVVAQMDAAWSL$ (서열번호:2469)
*DDPKLYDKDLGSAMTDWVVAQMDAAWSL (서열번호:2470)
*DDPKLYDKDLGSAMTDWVVAQMDAATSL$ (서열번호:2471)
*DDPKLYDKDLGSAMTDWVVAQMDAATSL (서열번호:2472)
*DDPKLYDKDLGSAMTDWVVGWVDAAWSL$ (서열번호:2473)
*DDPKLYDKDLGSAMTDWVVGWVDAAWSL (서열번호:2474)
*DDPKLYDKDLGSAMTDWVVGWVDAATSL$ (서열번호:2475)
*DDPKLYDKDLGSAMTDWVVGWVDAATSL (서열번호:2476)
*DDPKLYDKDLGSAMTDWVVGWLDAAWSL$ (서열번호:2477)
*DDPKLYDKDLGSAMTDWVVGWLDAAWSL (서열번호:2478)
*DDPKLYDKDLGSAMTDWVVGWLDAATSL$ (서열번호:2479)
*DDPKLYDKDLGSAMTDWVVGWLDAATSL (서열번호:2480)
*DDPKLYDKDLGSAMTDWVVGWMDAAWSL$ (서열번호:2481)
*DDPKLYDKDLGSAMTDWVVGWMDAAWSL (서열번호:2482)
*DDPKLYDKDLGSAMTDWVVGWMDAATSL$ (서열번호:2483)
*DDPKLYDKDLGSAMTDWVVGWMDAATSL (서열번호:2484)
*DDPKLYDKDLGSAMTDWVVGQVDAAWSL$ (서열번호:2485)
*DDPKLYDKDLGSAMTDWVVGQVDAAWSL (서열번호:2486)
*DDPKLYDKDLGSAMTDWVVGQVDAATSL$ (서열번호:2487)
*DDPKLYDKDLGSAMTDWVVGQVDAATSL (서열번호:2488)
*DDPKLYDKDLGSAMTDWVVGQLDAAWSL$ (서열번호:2489)
*DDPKLYDKDLGSAMTDWVVGQLDAAWSL (서열번호:2490)
*DDPKLYDKDLGSAMTDWVVGQLDAATSL$ (서열번호:2491)
*DDPKLYDKDLGSAMTDWVVGQLDAATSL (서열번호:2492)
*DDPKLYDKDLGSAMTDWVVGQMDAAWSL$ (서열번호:2493)
*DDPKLYDKDLGSAMTDWVVGQMDAAWSL (서열번호:2494)
*DDPKLYDKDLGSAMTDWVVGQMDAATSL$ (서열번호:2495)
*DDPKLYDKDLGSAMTDWVVGQMDAATSL (서열번호:2496)
*DDPKLYDKDLGSAMTDTVVAWVDAAWSL$ (서열번호:2497)
*DDPKLYDKDLGSAMTDTVVAWVDAAWSL (서열번호:2498)
*DDPKLYDKDLGSAMTDTVVAWVDAATSL$ (서열번호:2499)
*DDPKLYDKDLGSAMTDTVVAWVDAATSL (서열번호:2500)
*DDPKLYDKDLGSAMTDTVVAWLDAAWSL$ (서열번호:2501)
*DDPKLYDKDLGSAMTDTVVAWLDAAWSL (서열번호:2502)
*DDPKLYDKDLGSAMTDTVVAWLDAATSL$ (서열번호:2503)
*DDPKLYDKDLGSAMTDTVVAWLDAATSL (서열번호:2504)
*DDPKLYDKDLGSAMTDTVVAWMDAAWSL$ (서열번호:2505)
*DDPKLYDKDLGSAMTDTVVAWMDAAWSL (서열번호:2506)
*DDPKLYDKDLGSAMTDTVVAWMDAATSL$ (서열번호:2507)
*DDPKLYDKDLGSAMTDTVVAWMDAATSL (서열번호:2508)
*DDPKLYDKDLGSAMTDTVVAQVDAAWSL$ (서열번호:2509)
*DDPKLYDKDLGSAMTDTVVAQVDAAWSL (서열번호:2510)
*DDPKLYDKDLGSAMTDTVVAQVDAATSL$ (서열번호:2511)
*DDPKLYDKDLGSAMTDTVVAQVDAATSL (서열번호:2512)
*DDPKLYDKDLGSAMTDTVVAQLDAAWSL$ (서열번호:2513)
*DDPKLYDKDLGSAMTDTVVAQLDAAWSL (서열번호:2514)
*DDPKLYDKDLGSAMTDTVVAQLDAATSL$ (서열번호:2515)
*DDPKLYDKDLGSAMTDTVVAQLDAATSL (서열번호:2516)
*DDPKLYDKDLGSAMTDTVVAQMDAAWSL$ (서열번호:2517)
*DDPKLYDKDLGSAMTDTVVAQMDAAWSL (서열번호:2518)
*DDPKLYDKDLGSAMTDTVVAQMDAATSL$ (서열번호:2519)
*DDPKLYDKDLGSAMTDTVVAQMDAATSL (서열번호:2520)
*DDPKLYDKDLGSAMTDTVVGWVDAAWSL$ (서열번호:2521)
*DDPKLYDKDLGSAMTDTVVGWVDAAWSL (서열번호:2522)
*DDPKLYDKDLGSAMTDTVVGWVDAATSL$ (서열번호:2523)
*DDPKLYDKDLGSAMTDTVVGWVDAATSL (서열번호:2524)
*DDPKLYDKDLGSAMTDTVVGWLDAAWSL$ (서열번호:2525)
*DDPKLYDKDLGSAMTDTVVGWLDAAWSL (서열번호:2526)
*DDPKLYDKDLGSAMTDTVVGWLDAATSL$ (서열번호:2527)
*DDPKLYDKDLGSAMTDTVVGWLDAATSL (서열번호:2528)
*DDPKLYDKDLGSAMTDTVVGWMDAAWSL$ (서열번호:2529)
*DDPKLYDKDLGSAMTDTVVGWMDAAWSL (서열번호:2530)
*DDPKLYDKDLGSAMTDTVVGWMDAATSL$ (서열번호:2531)
*DDPKLYDKDLGSAMTDTVVGWMDAATSL (서열번호:2532)
*DDPKLYDKDLGSAMTDTVVGQVDAAWSL$ (서열번호:2533)
*DDPKLYDKDLGSAMTDTVVGQVDAAWSL (서열번호:2534)
*DDPKLYDKDLGSAMTDTVVGQVDAATSL$ (서열번호:2535)
*DDPKLYDKDLGSAMTDTVVGQVDAATSL (서열번호:2536)
*DDPKLYDKDLGSAMTDTVVGQLDAAWSL$ (서열번호:2537)
*DDPKLYDKDLGSAMTDTVVGQLDAAWSL (서열번호:2538)
*DDPKLYDKDLGSAMTDTVVGQLDAATSL$ (서열번호:2539)
*DDPKLYDKDLGSAMTDTVVGQLDAATSL (서열번호:2540)
*DDPKLYDKDLGSAMTDTVVGQMDAAWSL$ (서열번호:2541)
*DDPKLYDKDLGSAMTDTVVGQMDAAWSL (서열번호:2542)
*DDPKLYDKDLGSAMTDTVVGQMDAATSL$ (서열번호:2543)
*DDPKLYDKDLGSAMTDTVVGQMDAATSL (서열번호:2544)
*DDPKLYDKDLGSAMGDWVVAWVDAAWSL$ (서열번호:2545)
*DDPKLYDKDLGSAMGDWVVAWVDAAWSL (서열번호:2546)
*DDPKLYDKDLGSAMGDWVVAWVDAATSL$ (서열번호:2547)
*DDPKLYDKDLGSAMGDWVVAWVDAATSL (서열번호:2548)
*DDPKLYDKDLGSAMGDWVVAWLDAAWSL$ (서열번호:2549)
*DDPKLYDKDLGSAMGDWVVAWLDAAWSL (서열번호:2550)
*DDPKLYDKDLGSAMGDWVVAWLDAATSL$ (서열번호:2551)
*DDPKLYDKDLGSAMGDWVVAWLDAATSL (서열번호:2552)
*DDPKLYDKDLGSAMGDWVVAWMDAAWSL$ (서열번호:2553)
*DDPKLYDKDLGSAMGDWVVAWMDAAWSL (서열번호:2554)
*DDPKLYDKDLGSAMGDWVVAWMDAATSL$ (서열번호:2555)
*DDPKLYDKDLGSAMGDWVVAWMDAATSL (서열번호:2556)
*DDPKLYDKDLGSAMGDWVVAQVDAAWSL$ (서열번호:2557)
*DDPKLYDKDLGSAMGDWVVAQVDAAWSL (서열번호:2558)
*DDPKLYDKDLGSAMGDWVVAQVDAATSL$ (서열번호:2559)
*DDPKLYDKDLGSAMGDWVVAQVDAATSL (서열번호:2560)
*DDPKLYDKDLGSAMGDWVVAQLDAAWSL$ (서열번호:2561)
*DDPKLYDKDLGSAMGDWVVAQLDAAWSL (서열번호:2562)
*DDPKLYDKDLGSAMGDWVVAQLDAATSL$ (서열번호:2563)
*DDPKLYDKDLGSAMGDWVVAQLDAATSL (서열번호:2564)
*DDPKLYDKDLGSAMGDWVVAQMDAAWSL$ (서열번호:2565)
*DDPKLYDKDLGSAMGDWVVAQMDAAWSL (서열번호:2566)
*DDPKLYDKDLGSAMGDWVVAQMDAATSL$ (서열번호:2567)
*DDPKLYDKDLGSAMGDWVVAQMDAATSL (서열번호:2568)
*DDPKLYDKDLGSAMGDWVVGWVDAAWSL$ (서열번호:2569)
*DDPKLYDKDLGSAMGDWVVGWVDAAWSL (서열번호:2570)
*DDPKLYDKDLGSAMGDWVVGWVDAATSL$ (서열번호:2571)
*DDPKLYDKDLGSAMGDWVVGWVDAATSL (서열번호:2572)
*DDPKLYDKDLGSAMGDWVVGWLDAAWSL$ (서열번호:2573)
*DDPKLYDKDLGSAMGDWVVGWLDAAWSL (서열번호:2574)
*DDPKLYDKDLGSAMGDWVVGWLDAATSL$ (서열번호:2575)
*DDPKLYDKDLGSAMGDWVVGWLDAATSL (서열번호:2576)
*DDPKLYDKDLGSAMGDWVVGWMDAAWSL$ (서열번호:2577)
*DDPKLYDKDLGSAMGDWVVGWMDAAWSL (서열번호:2578)
*DDPKLYDKDLGSAMGDWVVGWMDAATSL$ (서열번호:2579)
*DDPKLYDKDLGSAMGDWVVGWMDAATSL (서열번호:2580)
*DDPKLYDKDLGSAMGDWVVGQVDAAWSL$ (서열번호:2581)
*DDPKLYDKDLGSAMGDWVVGQVDAAWSL (서열번호:2582)
*DDPKLYDKDLGSAMGDWVVGQVDAATSL$ (서열번호:2583)
*DDPKLYDKDLGSAMGDWVVGQVDAATSL (서열번호:2584)
*DDPKLYDKDLGSAMGDWVVGQLDAAWSL$ (서열번호:2585)
*DDPKLYDKDLGSAMGDWVVGQLDAAWSL (서열번호:2586)
*DDPKLYDKDLGSAMGDWVVGQLDAATSL$ (서열번호:2587)
*DDPKLYDKDLGSAMGDWVVGQLDAATSL (서열번호:2588)
*DDPKLYDKDLGSAMGDWVVGQMDAAWSL$ (서열번호:2589)
*DDPKLYDKDLGSAMGDWVVGQMDAAWSL (서열번호:2590)
*DDPKLYDKDLGSAMGDWVVGQMDAATSL$ (서열번호:2591)
*DDPKLYDKDLGSAMGDWVVGQMDAATSL (서열번호:2592)
*DDPKLYDKDLGSAMGDTVVAWVDAAWSL$ (서열번호:2593)
*DDPKLYDKDLGSAMGDTVVAWVDAAWSL (서열번호:2594)
*DDPKLYDKDLGSAMGDTVVAWVDAATSL$ (서열번호:2595)
*DDPKLYDKDLGSAMGDTVVAWVDAATSL (서열번호:2596)
*DDPKLYDKDLGSAMGDTVVAWLDAAWSL$ (서열번호:2597)
*DDPKLYDKDLGSAMGDTVVAWLDAAWSL (서열번호:2598)
*DDPKLYDKDLGSAMGDTVVAWLDAATSL$ (서열번호:2599)
*DDPKLYDKDLGSAMGDTVVAWLDAATSL (서열번호:2600)
*DDPKLYDKDLGSAMGDTVVAWMDAAWSL$ (서열번호:2601)
*DDPKLYDKDLGSAMGDTVVAWMDAAWSL (서열번호:2602)
*DDPKLYDKDLGSAMGDTVVAWMDAATSL$ (서열번호:2603)
*DDPKLYDKDLGSAMGDTVVAWMDAATSL (서열번호:2604)
*DDPKLYDKDLGSAMGDTVVAQVDAAWSL$ (서열번호:2605)
*DDPKLYDKDLGSAMGDTVVAQVDAAWSL (서열번호:2606)
*DDPKLYDKDLGSAMGDTVVAQVDAATSL$ (서열번호:2607)
*DDPKLYDKDLGSAMGDTVVAQVDAATSL (서열번호:2608)
*DDPKLYDKDLGSAMGDTVVAQLDAAWSL$ (서열번호:2609)
*DDPKLYDKDLGSAMGDTVVAQLDAAWSL (서열번호:2610)
*DDPKLYDKDLGSAMGDTVVAQLDAATSL$ (서열번호:2611)
*DDPKLYDKDLGSAMGDTVVAQLDAATSL (서열번호:2612)
*DDPKLYDKDLGSAMGDTVVAQMDAAWSL$ (서열번호:2613)
*DDPKLYDKDLGSAMGDTVVAQMDAAWSL (서열번호:2614)
*DDPKLYDKDLGSAMGDTVVAQMDAATSL$ (서열번호:2615)
*DDPKLYDKDLGSAMGDTVVAQMDAATSL (서열번호:2616)
*DDPKLYDKDLGSAMGDTVVGWVDAAWSL$ (서열번호:2617)
*DDPKLYDKDLGSAMGDTVVGWVDAAWSL (서열번호:2618)
*DDPKLYDKDLGSAMGDTVVGWVDAATSL$ (서열번호:2619)
*DDPKLYDKDLGSAMGDTVVGWVDAATSL (서열번호:2620)
*DDPKLYDKDLGSAMGDTVVGWLDAAWSL$ (서열번호:2621)
*DDPKLYDKDLGSAMGDTVVGWLDAAWSL (서열번호:2622)
*DDPKLYDKDLGSAMGDTVVGWLDAATSL$ (서열번호:2623)
*DDPKLYDKDLGSAMGDTVVGWLDAATSL (서열번호:2624)
*DDPKLYDKDLGSAMGDTVVGWMDAAWSL$ (서열번호:2625)
*DDPKLYDKDLGSAMGDTVVGWMDAAWSL (서열번호:2626)
*DDPKLYDKDLGSAMGDTVVGWMDAATSL$ (서열번호:2627)
*DDPKLYDKDLGSAMGDTVVGWMDAATSL (서열번호:2628)
*DDPKLYDKDLGSAMGDTVVGQVDAAWSL$ (서열번호:2629)
*DDPKLYDKDLGSAMGDTVVGQVDAAWSL (서열번호:2630)
*DDPKLYDKDLGSAMGDTVVGQVDAATSL$ (서열번호:2631)
*DDPKLYDKDLGSAMGDTVVGQVDAATSL (서열번호:2632)
*DDPKLYDKDLGSAMGDTVVGQLDAAWSL$ (서열번호:2633)
*DDPKLYDKDLGSAMGDTVVGQLDAAWSL (서열번호:2634)
*DDPKLYDKDLGSAMGDTVVGQLDAATSL$ (서열번호:2635)
*DDPKLYDKDLGSAMGDTVVGQLDAATSL (서열번호:2636)
*DDPKLYDKDLGSAMGDTVVGQMDAAWSL$ (서열번호:2637)
*DDPKLYDKDLGSAMGDTVVGQMDAAWSL (서열번호:2638)
*DDPKLYDKDLGSAMGDTVVGQMDAATSL$ (서열번호:2639)
*DDPKLLLSSAMGDVVVGQMDATTSL (서열번호:2640)
DDPKLYDKDLGSAVWDWVVAWVDAAWSL$ (서열번호:2641)
DDPKLYDKDLGSAVWDWVVAWVDAAWSL (서열번호:2642)
DDPKLYDKDLGSAVWDWVVAWVDAATSL$ (서열번호:2643)
DDPKLYDKDLGSAVWDWVVAWVDAATSL (서열번호:2644)
DDPKLYDKDLGSAVWDWVVAWLDAAWSL$ (서열번호:2645)
DDPKLYDKDLGSAVWDWVVAWLDAAWSL (서열번호:2646)
DDPKLYDKDLGSAVWDWVVAWLDAATSL$ (서열번호:2647)
DDPKLYDKDLGSAVWDWVVAWLDAATSL (서열번호:2648)
DDPKLYDKDLGSAVWDWVVAWMDAAWSL$ (서열번호:2649)
DDPKLYDKDLGSAVWDWVVAWMDAAWSL (서열번호:2650)
DDPKLYDKDLGSAVWDWVVAWMDAATSL$ (서열번호:2651)
DDPKLYDKDLGSAVWDWVVAWMDAATSL (서열번호:2652)
DDPKLYDKDLGSAVWDWVVAQVDAAWSL$ (서열번호:2653)
DDPKLYDKDLGSAVWDWVVAQVDAAWSL (서열번호:2654)
DDPKLYDKDLGSAVWDWVVAQVDAATSL$ (서열번호:2655)
DDPKLYDKDLGSAVWDWVVAQVDAATSL (서열번호:2656)
DDPKLYDKDLGSAVWDWVVAQLDAAWSL$ (서열번호:2657)
DDPKLYDKDLGSAVWDWVVAQLDAAWSL (서열번호:2658)
DDPKLYDKDLGSAVWDWVVAQLDAATSL$ (서열번호:2659)
DDPKLYDKDLGSAVWDWVVAQLDAATSL (서열번호:2660)
DDPKLYDKDLGSAVWDWVVAQMDAAWSL$ (서열번호:2661)
DDPKLYDKDLGSAVWDWVVAQMDAAWSL (서열번호:2662)
DDPKLYDKDLGSAVWDWVVAQMDAATSL$ (서열번호:2663)
DDPKLYDKDLGSAVWDWVVAQMDAATSL (서열번호:2664)
DDPKLYDKDLGSAVWDWVVGWVDAAWSL$ (서열번호:2665)
DDPKLYDKDLGSAVWDWVVGWVDAAWSL (서열번호:2666)
DDPKLYDKDLGSAVWDWVVGWVDAATSL$ (서열번호:2667)
DDPKLYDKDLGSAVWDWVVGWVDAATSL (서열번호:2668)
DDPKLYDKDLGSAVWDWVVGWLDAAWSL$ (서열번호:2669)
DDPKLYDKDLGSAVWDWVVGWLDAAWSL (서열번호:2670)
DDPKLYDKDLGSAVWDWVVGWLDAATSL$ (서열번호:2671)
DDPKLYDKDLGSAVWDWVVGWLDAATSL (서열번호:2672)
DDPKLYDKDLGSAVWDWVVGWMDAAWSL$ (서열번호:2673)
DDPKLYDKDLGSAVWDWVVGWMDAAWSL (서열번호:2674)
DDPKLYDKDLGSAVWDWVVGWMDAATSL$ (서열번호:2675)
DDPKLYDKDLGSAVWDWVVGWMDAATSL (서열번호:2676)
DDPKLYDKDLGSAVWDWVVGQVDAAWSL$ (서열번호:2677)
DDPKLYDKDLGSAVWDWVVGQVDAAWSL (서열번호:2678)
DDPKLYDKDLGSAVWDWVVGQVDAATSL$ (서열번호:2679)
DDPKLYDKDLGSAVWDWVVGQVDAATSL (서열번호:2680)
DDPKLYDKDLGSAVWDWVVGQLDAAWSL$ (서열번호:2681)
DDPKLYDKDLGSAVWDWVVGQLDAAWSL (서열번호:2682)
DDPKLYDKDLGSAVWDWVVGQLDAATSL$ (서열번호:2683)
DDPKLYDKDLGSAVWDWVVGQLDAATSL (서열번호:2684)
DDPKLYDKDLGSAVWDWVVGQMDAAWSL$ (서열번호:2685)
DDPKLYDKDLGSAVWDWVVGQMDAAWSL (서열번호:2686)
DDPKLYDKDLGSAVWDWVVGQMDAATSL$ (서열번호:2687)
DDPKLYDKDLGSAVWDWVVGQMDAATSL (서열번호:2688)
DDPKLYDKDLGSAVWDTVVAWVDAAWSL$ (서열번호:2689)
DDPKLYDKDLGSAVWDTVVAWVDAAWSL (서열번호:2690)
DDPKLYDKDLGSAVWDTVVAWVDAATSL$ (서열번호:2691)
DDPKLYDKDLGSAVWDTVVAWVDAATSL (서열번호:2692)
DDPKLYDKDLGSAVWDTVVAWLDAAWSL$ (서열번호:2693)
DDPKLYDKDLGSAVWDTVVAWLDAAWSL (서열번호:2694)
DDPKLYDKDLGSAVWDTVVAWLDAATSL$ (서열번호:2695)
DDPKLYDKDLGSAVWDTVVAWLDAATSL (서열번호:2696)
DDPKLYDKDLGSAVWDTVVAWMDAAWSL$ (서열번호:2697)
DDPKLYDKDLGSAVWDTVVAWMDAAWSL (서열번호:2698)
DDPKLYDKDLGSAVWDTVVAWMDAATSL$ (서열번호:2699)
DDPKLYDKDLGSAVWDTVVAWMDAATSL (서열번호:2700)
DDPKLYDKDLGSAVWDTVVAQVDAAWSL$ (서열번호:2701)
DDPKLYDKDLGSAVWDTVVAQVDAAWSL (서열번호:2702)
DDPKLYDKDLGSAVWDTVVAQVDAATSL$ (서열번호:2703)
DDPKLYDKDLGSAVWDTVVAQVDAATSL (서열번호:2704)
DDPKLYDKDLGSAVWDTVVAQLDAAWSL$ (서열번호:2705)
DDPKLYDKDLGSAVWDTVVAQLDAAWSL (서열번호:2706)
DDPKLYDKDLGSAVWDTVVAQLDAATSL$ (서열번호:2707)
DDPKLYDKDLGSAVWDTVVAQLDAATSL (서열번호:2708)
DDPKLYDKDLGSAVWDTVVAQMDAAWSL$ (서열번호:2709)
DDPKLYDKDLGSAVWDTVVAQMDAAWSL (서열번호:2710)
DDPKLYDKDLGSAVWDTVVAQMDAATSL$ (서열번호:2711)
DDPKLYDKDLGSAVWDTVVAQMDAATSL (서열번호:2712)
DDPKLYDKDLGSAVWDTVVGWVDAAWSL$ (서열번호:2713)
DDPKLYDKDLGSAVWDTVVGWVDAAWSL (서열번호:2714)
DDPKLYDKDLGSAVWDTVVGWVDAATSL$ (서열번호:2715)
DDPKLYDKDLGSAVWDTVVGWVDAATSL (서열번호:2716)
DDPKLYDKDLGSAVWDTVVGWLDAAWSL$ (서열번호:2717)
DDPKLYDKDLGSAVWDTVVGWLDAAWSL (서열번호:2718)
DDPKLYDKDLGSAVWDTVVGWLDAATSL$ (서열번호:2719)
DDPKLYDKDLGSAVWDTVVGWLDAATSL (서열번호:2720)
DDPKLYDKDLGSAVWDTVVGWMDAAWSL$ (서열번호:2721)
DDPKLYDKDLGSAVWDTVVGWMDAAWSL (서열번호:2722)
DDPKLYDKDLGSAVWDTVVGWMDAATSL$ (서열번호:2723)
DDPKLYDKDLGSAVWDTVVGWMDAATSL (서열번호:2724)
DDPKLYDKDLGSAVWDTVVGQVDAAWSL$ (서열번호:2725)
DDPKLYDKDLGSAVWDTVVGQVDAAWSL (서열번호:2726)
DDPKLYDKDLGSAVWDTVVGQVDAATSL$ (서열번호:2727)
DDPKLYDKDLGSAVWDTVVGQVDAATSL (서열번호:2728)
DDPKLYDKDLGSAVWDTVVGQLDAAWSL$ (서열번호:2729)
DDPKLYDKDLGSAVWDTVVGQLDAAWSL (서열번호:2730)
DDPKLYDKDLGSAVWDTVVGQLDAATSL$ (서열번호:2731)
DDPKLYDKDLGSAVWDTVVGQLDAATSL (서열번호:2732)
DDPKLYDKDLGSAVWDTVVGQMDAAWSL$ (서열번호:2733)
DDPKLYDKDLGSAVWDTVVGQMDAAWSL (서열번호:2734)
DDPKLYDKDLGSAVWDTVVGQMDAATSL$ (서열번호:2735)
DDPKLYDKDLGSAVWDTVVGQMDAATSL (서열번호:2736)
DDPKLYDKDLGSAVTDWVVAWVDAAWSL$ (서열번호:2737)
DDPKLYDKDLGSAVTDWVVAWVDAAWSL (서열번호:2738)
DDPKLYDKDLGSAVTDWVVAWVDAATSL$ (서열번호:2739)
DDPKLYDKDLGSAVTDWVVAWVDAATSL (서열번호:2740)
DDPKLYDKDLGSAVTDWVVAWLDAAWSL$ (서열번호:2741)
DDPKLYDKDLGSAVTDWVVAWLDAAWSL (서열번호:2742)
DDPKLYDKDLGSAVTDWVVAWLDAATSL$ (서열번호:2743)
DDPKLYDKDLGSAVTDWVVAWLDAATSL (서열번호:2744)
DDPKLYDKDLGSAVTDWVVAWMDAAWSL$ (서열번호:2745)
DDPKLYDKDLGSAVTDWVVAWMDAAWSL (서열번호:2746)
DDPKLYDKDLGSAVTDWVVAWMDAATSL$ (서열번호:2747)
DDPKLYDKDLGSAVTDWVVAWMDAATSL (서열번호:2748)
DDPKLYDKDLGSAVTDWVVAQVDAAWSL$ (서열번호:2749)
DDPKLYDKDLGSAVTDWVVAQVDAAWSL (서열번호:2750)
DDPKLYDKDLGSAVTDWVVAQVDAATSL$ (서열번호:2751)
DDPKLYDKDLGSAVTDWVVAQVDAATSL (서열번호:2752)
DDPKLYDKDLGSAVTDWVVAQLDAAWSL$ (서열번호:2753)
DDPKLYDKDLGSAVTDWVVAQLDAAWSL (서열번호:2754)
DDPKLYDKDLGSAVTDWVVAQLDAATSL$ (서열번호:2755)
DDPKLYDKDLGSAVTDWVVAQLDAATSL (서열번호:2756)
DDPKLYDKDLGSAVTDWVVAQMDAAWSL$ (서열번호:2757)
DDPKLYDKDLGSAVTDWVVAQMDAAWSL (서열번호:2758)
DDPKLYDKDLGSAVTDWVVAQMDAATSL$ (서열번호:2759)
DDPKLYDKDLGSAVTDWVVAQMDAATSL (서열번호:2760)
DDPKLYDKDLGSAVTDWVVGWVDAAWSL$ (서열번호:2761)
DDPKLYDKDLGSAVTDWVVGWVDAAWSL (서열번호:2762)
DDPKLYDKDLGSAVTDWVVGWVDAATSL$ (서열번호:2763)
DDPKLYDKDLGSAVTDWVVGWVDAATSL (서열번호:2764)
DDPKLYDKDLGSAVTDWVVGWLDAAWSL$ (서열번호:2765)
DDPKLYDKDLGSAVTDWVVGWLDAAWSL (서열번호:2766)
DDPKLYDKDLGSAVTDWVVGWLDAATSL$ (서열번호:2767)
DDPKLYDKDLGSAVTDWVVGWLDAATSL (서열번호:2768)
DDPKLYDKDLGSAVTDWVVGWMDAAWSL$ (서열번호:2769)
DDPKLYDKDLGSAVTDWVVGWMDAAWSL (서열번호:2770)
DDPKLYDKDLGSAVTDWVVGWMDAATSL$ (서열번호:2771)
DDPKLYDKDLGSAVTDWVVGWMDAATSL (서열번호:2772)
DDPKLYDKDLGSAVTDWVVGQVDAAWSL$ (서열번호:2773)
DDPKLYDKDLGSAVTDWVVGQVDAAWSL (서열번호:2774)
DDPKLYDKDLGSAVTDWVVGQVDAATSL$ (서열번호:2775)
DDPKLYDKDLGSAVTDWVVGQVDAATSL (서열번호:2776)
DDPKLYDKDLGSAVTDWVVGQLDAAWSL$ (서열번호:2777)
DDPKLYDKDLGSAVTDWVVGQLDAAWSL (서열번호:2778)
DDPKLYDKDLGSAVTDWVVGQLDAATSL$ (서열번호:2779)
DDPKLYDKDLGSAVTDWVVGQLDAATSL (서열번호:2780)
DDPKLYDKDLGSAVTDWVVGQMDAAWSL$ (서열번호:2781)
DDPKLYDKDLGSAVTDWVVGQMDAAWSL (서열번호:2782)
DDPKLYDKDLGSAVTDWVVGQMDAATSL$ (서열번호:2783)
DDPKLYDKDLGSAVTDWVVGQMDAATSL (서열번호:2784)
DDPKLYDKDLGSAVTDTVVAWVDAAWSL$ (서열번호:2785)
DDPKLYDKDLGSAVTDTVVAWVDAAWSL (서열번호:2786)
DDPKLYDKDLGSAVTDTVVAWVDAATSL$ (서열번호:2787)
DDPKLYDKDLGSAVTDTVVAWVDAATSL (서열번호:2788)
DDPKLYDKDLGSAVTDTVVAWLDAAWSL$ (서열번호:2789)
DDPKLYDKDLGSAVTDTVVAWLDAAWSL (서열번호:2790)
DDPKLYDKDLGSAVTDTVVAWLDAATSL$ (서열번호:2791)
DDPKLYDKDLGSAVTDTVVAWLDAATSL (서열번호:2792)
DDPKLYDKDLGSAVTDTVVAWMDAAWSL$ (서열번호:2793)
DDPKLYDKDLGSAVTDTVVAWMDAAWSL (서열번호:2794)
DDPKLYDKDLGSAVTDTVVAWMDAATSL$ (서열번호:2795)
DDPKLYDKDLGSAVTDTVVAWMDAATSL (서열번호:2796)
DDPKLYDKDLGSAVTDTVVAQVDAAWSL$ (서열번호:2797)
DDPKLYDKDLGSAVTDTVVAQVDAAWSL (서열번호:2798)
DDPKLYDKDLGSAVTDTVVAQVDAATSL$ (서열번호:2799)
DDPKLYDKDLGSAVTDTVVAQVDAATSL (서열번호:2800)
DDPKLYDKDLGSAVTDTVVAQLDAAWSL$ (서열번호:2801)
DDPKLYDKDLGSAVTDTVVAQLDAAWSL (서열번호:2802)
DDPKLYDKDLGSAVTDTVVAQLDAATSL$ (서열번호:2803)
DDPKLYDKDLGSAVTDTVVAQLDAATSL (서열번호:2804)
DDPKLYDKDLGSAVTDTVVAQMDAAWSL$ (서열번호:2805)
DDPKLYDKDLGSAVTDTVVAQMDAAWSL (서열번호:2806)
DDPKLYDKDLGSAVTDTVVAQMDAATSL$ (서열번호:2807)
DDPKLYDKDLGSAVTDTVVAQMDAATSL (서열번호:2808)
DDPKLYDKDLGSAVTDTVVGWVDAAWSL$ (서열번호:2809)
DDPKLYDKDLGSAVTDTVVGWVDAAWSL (서열번호:2810)
DDPKLYDKDLGSAVTDTVVGWVDAATSL$ (서열번호:2811)
DDPKLYDKDLGSAVTDTVVGWVDAATSL (서열번호:2812)
DDPKLYDKDLGSAVTDTVVGWLDAAWSL$ (서열번호:2813)
DDPKLYDKDLGSAVTDTVVGWLDAAWSL (서열번호:2814)
DDPKLYDKDLGSAVTDTVVGWLDAATSL$ (서열번호:2815)
DDPKLYDKDLGSAVTDTVVGWLDAATSL (서열번호:2816)
DDPKLYDKDLGSAVTDTVVGWMDAAWSL$ (서열번호:2817)
DDPKLYDKDLGSAVTDTVVGWMDAAWSL (서열번호:2818)
DDPKLYDKDLGSAVTDTVVGWMDAATSL$ (서열번호:2819)
DDPKLYDKDLGSAVTDTVVGWMDAATSL (서열번호:2820)
DDPKLYDKDLGSAVTDTVVGQVDAAWSL$ (서열번호:2821)
DDPKLYDKDLGSAVTDTVVGQVDAAWSL (서열번호:2822)
DDPKLYDKDLGSAVTDTVVGQVDAATSL$ (서열번호:2823)
DDPKLYDKDLGSAVTDTVVGQVDAATSL (서열번호:2824)
DDPKLYDKDLGSAVTDTVVGQLDAAWSL$ (서열번호:2825)
DDPKLYDKDLGSAVTDTVVGQLDAAWSL (서열번호:2826)
DDPKLYDKDLGSAVTDTVVGQLDAATSL$ (서열번호:2827)
DDPKLYDKDLGSAVTDTVVGQLDAATSL (서열번호:2828)
DDPKLYDKDLGSAVTDTVVGQMDAAWSL$ (서열번호:2829)
DDPKLYDKDLGSAVTDTVVGQMDAAWSL (서열번호:2830)
DDPKLYDKDLGSAVTDTVVGQMDAATSL$ (서열번호:2831)
DDPKLYDKDLGSAVTDTVVGQMDAATSL (서열번호:2832)
DDPKLYDKDLGSAVGDWVVAWVDAAWSL$ (서열번호:2833)
DDPKLYDKDLGSAVGDWVVAWVDAAWSL (서열번호:2834)
DDPKLYDKDLGSAVGDWVVAWVDAATSL$ (서열번호:2835)
DDPKLYDKDLGSAVGDWVVAWVDAATSL (서열번호:2836)
DDPKLYDKDLGSAVGDWVVAWLDAAWSL$ (서열번호:2837)
DDPKLYDKDLGSAVGDWVVAWLDAAWSL (서열번호:2838)
DDPKLYDKDLGSAVGDWVVAWLDAATSL$ (서열번호:2839)
DDPKLYDKDLGSAVGDWVVAWLDAATSL (서열번호:2840)
DDPKLYDKDLGSAVGDWVVAWMDAAWSL$ (서열번호:2841)
DDPKLYDKDLGSAVGDWVVAWMDAAWSL (서열번호:2842)
DDPKLYDKDLGSAVGDWVVAWMDAATSL$ (서열번호:2843)
DDPKLYDKDLGSAVGDWVVAWMDAATSL (서열번호:2844)
DDPKLYDKDLGSAVGDWVVAQVDAAWSL$ (서열번호:2845)
DDPKLYDKDLGSAVGDWVVAQVDAAWSL (서열번호:2846)
DDPKLYDKDLGSAVGDWVVAQVDAATSL$ (서열번호:2847)
DDPKLYDKDLGSAVGDWVVAQVDAATSL (서열번호:2848)
DDPKLYDKDLGSAVGDWVVAQLDAAWSL$ (서열번호:2849)
DDPKLYDKDLGSAVGDWVVAQLDAAWSL (서열번호:2850)
DDPKLYDKDLGSAVGDWVVAQLDAATSL$ (서열번호:2851)
DDPKLYDKDLGSAVGDWVVAQLDAATSL (서열번호:2852)
DDPKLYDKDLGSAVGDWVVAQMDAAWSL$ (서열번호:2853)
DDPKLYDKDLGSAVGDWVVAQMDAAWSL (서열번호:2854)
DDPKLYDKDLGSAVGDWVVAQMDAATSL$ (서열번호:2855)
DDPKLYDKDLGSAVGDWVVAQMDAATSL (서열번호:2856)
DDPKLYDKDLGSAVGDWVVGWVDAAWSL$ (서열번호:2857)
DDPKLYDKDLGSAVGDWVVGWVDAAWSL (서열번호:2858)
DDPKLYDKDLGSAVGDWVVGWVDAATSL$ (서열번호:2859)
DDPKLYDKDLGSAVGDWVVGWVDAATSL (서열번호:2860)
DDPKLYDKDLGSAVGDWVVGWLDAAWSL$ (서열번호:2861)
DDPKLYDKDLGSAVGDWVVGWLDAAWSL (서열번호:2862)
DDPKLYDKDLGSAVGDWVVGWLDAATSL$ (서열번호:2863)
DDPKLYDKDLGSAVGDWVVGWLDAATSL (서열번호:2864)
DDPKLYDKDLGSAVGDWVVGWMDAAWSL$ (서열번호:2865)
DDPKLYDKDLGSAVGDWVVGWMDAAWSL (서열번호:2866)
DDPKLYDKDLGSAVGDWVVGWMDAATSL$ (서열번호:2867)
DDPKLYDKDLGSAVGDWVVGWMDAATSL (서열번호:2868)
DDPKLYDKDLGSAVGDWVVGQVDAAWSL$ (서열번호:2869)
DDPKLYDKDLGSAVGDWVVGQVDAAWSL (서열번호:2870)
DDPKLYDKDLGSAVGDWVVGQVDAATSL$ (서열번호:2871)
DDPKLYDKDLGSAVGDWVVGQVDAATSL (서열번호:2872)
DDPKLYDKDLGSAVGDWVVGQLDAAWSL$ (서열번호:2873)
DDPKLYDKDLGSAVGDWVVGQLDAAWSL (서열번호:2874)
DDPKLYDKDLGSAVGDWVVGQLDAATSL$ (서열번호:2875)
DDPKLYDKDLGSAVGDWVVGQLDAATSL (서열번호:2876)
DDPKLYDKDLGSAVGDWVVGQMDAAWSL$ (서열번호:2877)
DDPKLYDKDLGSAVGDWVVGQMDAAWSL (서열번호:2878)
DDPKLYDKDLGSAVGDWVVGQMDAATSL$ (서열번호:2879)
DDPKLYDKDLGSAVGDWVVGQMDAATSL (서열번호:2880)
DDPKLYDKDLGSAVGDTVVAWVDAAWSL$ (서열번호:2881)
DDPKLYDKDLGSAVGDTVVAWVDAAWSL (서열번호:2882)
DDPKLYDKDLGSAVGDTVVAWVDAATSL$ (서열번호:2883)
DDPKLYDKDLGSAVGDTVVAWVDAATSL (서열번호:2884)
DDPKLYDKDLGSAVGDTVVAWLDAAWSL$ (서열번호:2885)
DDPKLYDKDLGSAVGDTVVAWLDAAWSL (서열번호:2886)
DDPKLYDKDLGSAVGDTVVAWLDAATSL$ (서열번호:2887)
DDPKLYDKDLGSAVGDTVVAWLDAATSL (서열번호:2888)
DDPKLYDKDLGSAVGDTVVAWMDAAWSL$ (서열번호:2889)
DDPKLYDKDLGSAVGDTVVAWMDAAWSL (서열번호:2890)
DDPKLYDKDLGSAVGDTVVAWMDAATSL$ (서열번호:2891)
DDPKLYDKDLGSAVGDTVVAWMDAATSL (서열번호:2892)
DDPKLYDKDLGSAVGDTVVAQVDAAWSL$ (서열번호:2893)
DDPKLYDKDLGSAVGDTVVAQVDAAWSL (서열번호:2894)
DDPKLYDKDLGSAVGDTVVAQVDAATSL$ (서열번호:2895)
DDPKLYDKDLGSAVGDTVVAQVDAATSL (서열번호:2896)
DDPKLYDKDLGSAVGDTVVAQLDAAWSL$ (서열번호:2897)
DDPKLYDKDLGSAVGDTVVAQLDAAWSL (서열번호:2898)
DDPKLYDKDLGSAVGDTVVAQLDAATSL$ (서열번호:2899)
DDPKLYDKDLGSAVGDTVVAQLDAATSL (서열번호:2900)
DDPKLYDKDLGSAVGDTVVAQMDAAWSL$ (서열번호:2901)
DDPKLYDKDLGSAVGDTVVAQMDAAWSL (서열번호:2902)
DDPKLYDKDLGSAVGDTVVAQMDAATSL$ (서열번호:2903)
DDPKLYDKDLGSAVGDTVVAQMDAATSL (서열번호:2904)
DDPKLYDKDLGSAVGDTVVGWVDAAWSL$ (서열번호:2905)
DDPKLYDKDLGSAVGDTVVGWVDAAWSL (서열번호:2906)
DDPKLYDKDLGSAVGDTVVGWVDAATSL$ (서열번호:2907)
DDPKLYDKDLGSAVGDTVVGWVDAATSL (서열번호:2908)
DDPKLYDKDLGSAVGDTVVGWLDAAWSL$ (서열번호:2909)
DDPKLYDKDLGSAVGDTVVGWLDAAWSL (서열번호:2910)
DDPKLYDKDLGSAVGDTVVGWLDAATSL$ (서열번호:2911)
DDPKLYDKDLGSAVGDTVVGWLDAATSL (서열번호:2912)
DDPKLYDKDLGSAVGDTVVGWMDAAWSL$ (서열번호:2913)
DDPKLYDKDLGSAVGDTVVGWMDAAWSL (서열번호:2914)
DDPKLYDKDLGSAVGDTVVGWMDAATSL$ (서열번호:2915)
DDPKLYDKDLGSAVGDTVVGWMDAATSL (서열번호:2916)
DDPKLYDKDLGSAVGDTVVGQVDAAWSL$ (서열번호:2917)
DDPKLYDKDLGSAVGDTVVGQVDAAWSL (서열번호:2918)
DDPKLYDKDLGSAVGDTVVGQVDAATSL$ (서열번호:2919)
DDPKLYDKDLGSAVGDTVVGQVDAATSL (서열번호:2920)
DDPKLYDKDLGSAVGDTVVGQLDAAWSL$ (서열번호:2921)
DDPKLYDKDLGSAVGDTVVGQLDAAWSL (서열번호:2922)
DDPKLYDKDLGSAVGDTVVGQLDAATSL$ (서열번호:2923)
DDPKLYDKDLGSAVGDTVVGQLDAATSL (서열번호:2924)
DDPKLYDKDLGSAVGDTVVGQMDAAWSL$ (서열번호:2925)
DDPKLYDKDLGSAVGDTVVGQMDAAWSL (서열번호:2926)
DDPKLYDKDLGSAVGDTVVGQMDAATSL$ (서열번호:2927)
DDPKLYDKDLGSAVGDTVVGQMDAATSL (서열번호:2928)
DDPKLYDKDLGSALWDWVVAWVDAAWSL$ (서열번호:2929)
DDPKLYDKDLGSALWDWVVAWVDAAWSL (서열번호:2930)
DDPKLYDKDLGSALWDWVVAWVDAATSL$ (서열번호:2931)
DDPKLYDKDLGSALWDWVVAWVDAATSL (서열번호:2932)
DDPKLYDKDLGSALWDWVVAWLDAAWSL$ (서열번호:2933)
DDPKLYDKDLGSALWDWVVAWLDAAWSL (서열번호:2934)
DDPKLYDKDLGSALWDWVVAWLDAATSL$ (서열번호:2935)
DDPKLYDKDLGSALWDWVVAWLDAATSL (서열번호:2936)
DDPKLYDKDLGSALWDWVVAWMDAAWSL$ (서열번호:2937)
DDPKLYDKDLGSALWDWVVAWMDAAWSL (서열번호:2938)
DDPKLYDKDLGSALWDWVVAWMDAATSL$ (서열번호:2939)
DDPKLYDKDLGSALWDWVVAWMDAATSL (서열번호:2940)
DDPKLYDKDLGSALWDWVVAQVDAAWSL$ (서열번호:2941)
DDPKLYDKDLGSALWDWVVAQVDAAWSL (서열번호:2942)
DDPKLYDKDLGSALWDWVVAQVDAATSL$ (서열번호:2943)
DDPKLYDKDLGSALWDWVVAQVDAATSL (서열번호:2944)
DDPKLYDKDLGSALWDWVVAQLDAAWSL$ (서열번호:2945)
DDPKLYDKDLGSALWDWVVAQLDAAWSL (서열번호:2946)
DDPKLYDKDLGSALWDWVVAQLDAATSL$ (서열번호:2947)
DDPKLYDKDLGSALWDWVVAQLDAATSL (서열번호:2948)
DDPKLYDKDLGSALWDWVVAQMDAAWSL$ (서열번호:2949)
DDPKLYDKDLGSALWDWVVAQMDAAWSL (서열번호:2950)
DDPKLYDKDLGSALWDWVVAQMDAATSL$ (서열번호:2951)
DDPKLYDKDLGSALWDWVVAQMDAATSL (서열번호:2952)
DDPKLYDKDLGSALWDWVVGWVDAAWSL$ (서열번호:2953)
DDPKLYDKDLGSALWDWVVGWVDAAWSL (서열번호:2954)
DDPKLYDKDLGSALWDWVVGWVDAATSL$ (서열번호:2955)
DDPKLYDKDLGSALWDWVVGWVDAATSL (서열번호:2956)
DDPKLYDKDLGSALWDWVVGWLDAAWSL$ (서열번호:2957)
DDPKLYDKDLGSALWDWVVGWLDAAWSL (서열번호:2958)
DDPKLYDKDLGSALWDWVVGWLDAATSL$ (서열번호:2959)
DDPKLYDKDLGSALWDWVVGWLDAATSL (서열번호:2960)
DDPKLYDKDLGSALWDWVVGWMDAAWSL$ (서열번호:2961)
DDPKLYDKDLGSALWDWVVGWMDAAWSL (서열번호:2962)
DDPKLYDKDLGSALWDWVVGWMDAATSL$ (서열번호:2963)
DDPKLYDKDLGSALWDWVVGWMDAATSL (서열번호:2964)
DDPKLYDKDLGSALWDWVVGQVDAAWSL$ (서열번호:2965)
DDPKLYDKDLGSALWDWVVGQVDAAWSL (서열번호:2966)
DDPKLYDKDLGSALWDWVVGQVDAATSL$ (서열번호:2967)
DDPKLYDKDLGSALWDWVVGQVDAATSL (서열번호:2968)
DDPKLYDKDLGSALWDWVVGQLDAAWSL$ (서열번호:2969)
DDPKLYDKDLGSALWDWVVGQLDAAWSL (서열번호:2970)
DDPKLYDKDLGSALWDWVVGQLDAATSL$ (서열번호:2971)
DDPKLYDKDLGSALWDWVVGQLDAATSL (서열번호:2972)
DDPKLYDKDLGSALWDWVVGQMDAAWSL$ (서열번호:2973)
DDPKLYDKDLGSALWDWVVGQMDAAWSL (서열번호:2974)
DDPKLYDKDLGSALWDWVVGQMDAATSL$ (서열번호:2975)
DDPKLYDKDLGSALWDWVVGQMDAATSL (서열번호:2976)
DDPKLYDKDLGSALWDTVVAWVDAAWSL$ (서열번호:2977)
DDPKLYDKDLGSALWDTVVAWVDAAWSL (서열번호:2978)
DDPKLYDKDLGSALWDTVVAWVDAATSL$ (서열번호:2979)
DDPKLYDKDLGSALWDTVVAWVDAATSL (서열번호:2980)
DDPKLYDKDLGSALWDTVVAWLDAAWSL$ (서열번호:2981)
DDPKLYDKDLGSALWDTVVAWLDAAWSL (서열번호:2982)
DDPKLYDKDLGSALWDTVVAWLDAATSL$ (서열번호:2983)
DDPKLYDKDLGSALWDTVVAWLDAATSL (서열번호:2984)
DDPKLYDKDLGSALWDTVVAWMDAAWSL$ (서열번호:2985)
DDPKLYDKDLGSALWDTVVAWMDAAWSL (서열번호:2986)
DDPKLYDKDLGSALWDTVVAWMDAATSL$ (서열번호:2987)
DDPKLYDKDLGSALWDTVVAWMDAATSL (서열번호:2988)
DDPKLYDKDLGSALWDTVVAQVDAAWSL$ (서열번호:2989)
DDPKLYDKDLGSALWDTVVAQVDAAWSL (서열번호:2990)
DDPKLYDKDLGSALWDTVVAQVDAATSL$ (서열번호:2991)
DDPKLYDKDLGSALWDTVVAQVDAATSL (서열번호:2992)
DDPKLYDKDLGSALWDTVVAQLDAAWSL$ (서열번호:2993)
DDPKLYDKDLGSALWDTVVAQLDAAWSL (서열번호:2994)
DDPKLYDKDLGSALWDTVVAQLDAATSL$ (서열번호:2995)
DDPKLYDKDLGSALWDTVVAQLDAATSL (서열번호:2996)
DDPKLYDKDLGSALWDTVVAQMDAAWSL$ (서열번호:2997)
DDPKLYDKDLGSALWDTVVAQMDAAWSL (서열번호:2998)
DDPKLYDKDLGSALWDTVVAQMDAATSL$ (서열번호:2999)
DDPKLYDKDLGSALWDTVVAQMDAATSL (서열번호:3000)
DDPKLYDKDLGSALWDTVVGWVDAAWSL$ (서열번호:3001)
DDPKLYDKDLGSALWDTVVGWVDAAWSL (서열번호:3002)
DDPKLYDKDLGSALWDTVVGWVDAATSL$ (서열번호:3003)
DDPKLYDKDLGSALWDTVVGWVDAATSL (서열번호:3004)
DDPKLYDKDLGSALWDTVVGWLDAAWSL$ (서열번호:3005)
DDPKLYDKDLGSALWDTVVGWLDAAWSL (서열번호:3006)
DDPKLYDKDLGSALWDTVVGWLDAATSL$ (서열번호:3007)
DDPKLYDKDLGSALWDTVVGWLDAATSL (서열번호:3008)
DDPKLYDKDLGSALWDTVVGWMDAAWSL$ (서열번호:3009)
DDPKLYDKDLGSALWDTVVGWMDAAWSL (서열번호:3010)
DDPKLYDKDLGSALWDTVVGWMDAATSL$ (서열번호:3011)
DDPKLYDKDLGSALWDTVVGWMDAATSL (서열번호:3012)
DDPKLYDKDLGSALWDTVVGQVDAAWSL$ (서열번호:3013)
DDPKLYDKDLGSALWDTVVGQVDAAWSL (서열번호:3014)
DDPKLYDKDLGSALWDTVVGQVDAATSL$ (서열번호:3015)
DDPKLYDKDLGSALWDTVVGQVDAATSL (서열번호:3016)
DDPKLYDKDLGSALWDTVVGQLDAAWSL$ (서열번호:3017)
DDPKLYDKDLGSALWDTVVGQLDAAWSL (서열번호:3018)
DDPKLYDKDLGSALWDTVVGQLDAATSL$ (서열번호:3019)
DDPKLYDKDLGSALWDTVVGQLDAATSL (서열번호:3020)
DDPKLYDKDLGSALWDTVVGQMDAAWSL$ (서열번호:3021)
DDPKLYDKDLGSALWDTVVGQMDAAWSL (서열번호:3022)
DDPKLYDKDLGSALWDTVVGQMDAATSL$ (서열번호:3023)
DDPKLYDKDLGSALWDTVVGQMDAATSL (서열번호:3024)
DDPKLYDKDLGSALTDWVVAWVDAAWSL$ (서열번호:3025)
DDPKLYDKDLGSALTDWVVAWVDAAWSL (서열번호:3026)
DDPKLYDKDLGSALTDWVVAWVDAATSL$ (서열번호:3027)
DDPKLYDKDLGSALTDWVVAWVDAATSL (서열번호:3028)
DDPKLYDKDLGSALTDWVVAWLDAAWSL$ (서열번호:3029)
DDPKLYDKDLGSALTDWVVAWLDAAWSL (서열번호:3030)
DDPKLYDKDLGSALTDWVVAWLDAATSL$ (서열번호:3031)
DDPKLYDKDLGSALTDWVVAWLDAATSL (서열번호:3032)
DDPKLYDKDLGSALTDWVVAWMDAAWSL$ (서열번호:3033)
DDPKLYDKDLGSALTDWVVAWMDAAWSL (서열번호:3034)
DDPKLYDKDLGSALTDWVVAWMDAATSL$ (서열번호:3035)
DDPKLYDKDLGSALTDWVVAWMDAATSL (서열번호:3036)
DDPKLYDKDLGSALTDWVVAQVDAAWSL$ (서열번호:3037)
DDPKLYDKDLGSALTDWVVAQVDAAWSL (서열번호:3038)
DDPKLYDKDLGSALTDWVVAQVDAATSL$ (서열번호:3039)
DDPKLYDKDLGSALTDWVVAQVDAATSL (서열번호:3040)
DDPKLYDKDLGSALTDWVVAQLDAAWSL$ (서열번호:3041)
DDPKLYDKDLGSALTDWVVAQLDAAWSL (서열번호:3042)
DDPKLYDKDLGSALTDWVVAQLDAATSL$ (서열번호:3043)
DDPKLYDKDLGSALTDWVVAQLDAATSL (서열번호:3044)
DDPKLYDKDLGSALTDWVVAQMDAAWSL$ (서열번호:3045)
DDPKLYDKDLGSALTDWVVAQMDAAWSL (서열번호:3046)
DDPKLYDKDLGSALTDWVVAQMDAATSL$ (서열번호:3047)
DDPKLYDKDLGSALTDWVVAQMDAATSL (서열번호:3048)
DDPKLYDKDLGSALTDWVVGWVDAAWSL$ (서열번호:3049)
DDPKLYDKDLGSALTDWVVGWVDAAWSL (서열번호:3050)
DDPKLYDKDLGSALTDWVVGWVDAATSL$ (서열번호:3051)
DDPKLYDKDLGSALTDWVVGWVDAATSL (서열번호:3052)
DDPKLYDKDLGSALTDWVVGWLDAAWSL$ (서열번호:3053)
DDPKLYDKDLGSALTDWVVGWLDAAWSL (서열번호:3054)
DDPKLYDKDLGSALTDWVVGWLDAATSL$ (서열번호:3055)
DDPKLYDKDLGSALTDWVVGWLDAATSL (서열번호:3056)
DDPKLYDKDLGSALTDWVVGWMDAAWSL$ (서열번호:3057)
DDPKLYDKDLGSALTDWVVGWMDAAWSL (서열번호:3058)
DDPKLYDKDLGSALTDWVVGWMDAATSL$ (서열번호:3059)
DDPKLYDKDLGSALTDWVVGWMDAATSL (서열번호:3060)
DDPKLYDKDLGSALTDWVVGQVDAAWSL$ (서열번호:3061)
DDPKLYDKDLGSALTDWVVGQVDAAWSL (서열번호:3062)
DDPKLYDKDLGSALTDWVVGQVDAATSL$ (서열번호:3063)
DDPKLYDKDLGSALTDWVVGQVDAATSL (서열번호:3064)
DDPKLYDKDLGSALTDWVVGQLDAAWSL$ (서열번호:3065)
DDPKLYDKDLGSALTDWVVGQLDAAWSL (서열번호:3066)
DDPKLYDKDLGSALTDWVVGQLDAATSL$ (서열번호:3067)
DDPKLYDKDLGSALTDWVVGQLDAATSL (서열번호:3068)
DDPKLYDKDLGSALTDWVVGQMDAAWSL$ (서열번호:3069)
DDPKLYDKDLGSALTDWVVGQMDAAWSL (서열번호:3070)
DDPKLYDKDLGSALTDWVVGQMDAATSL$ (서열번호:3071)
DDPKLYDKDLGSALTDWVVGQMDAATSL (서열번호:3072)
DDPKLYDKDLGSALTDTVVAWVDAAWSL$ (서열번호:3073)
DDPKLYDKDLGSALTDTVVAWVDAAWSL (서열번호:3074)
DDPKLYDKDLGSALTDTVVAWVDAATSL$ (서열번호:3075)
DDPKLYDKDLGSALTDTVVAWVDAATSL (서열번호:3076)
DDPKLYDKDLGSALTDTVVAWLDAAWSL$ (서열번호:3077)
DDPKLYDKDLGSALTDTVVAWLDAAWSL (서열번호:3078)
DDPKLYDKDLGSALTDTVVAWLDAATSL$ (서열번호:3079)
DDPKLYDKDLGSALTDTVVAWLDAATSL (서열번호:3080)
DDPKLYDKDLGSALTDTVVAWMDAAWSL$ (서열번호:3081)
DDPKLYDKDLGSALTDTVVAWMDAAWSL (서열번호:3082)
DDPKLYDKDLGSALTDTVVAWMDAATSL$ (서열번호:3083)
DDPKLYDKDLGSALTDTVVAWMDAATSL (서열번호:3084)
DDPKLYDKDLGSALTDTVVAQVDAAWSL$ (서열번호:3085)
DDPKLYDKDLGSALTDTVVAQVDAAWSL (서열번호:3086)
DDPKLYDKDLGSALTDTVVAQVDAATSL$ (서열번호:3087)
DDPKLYDKDLGSALTDTVVAQVDAATSL (서열번호:3088)
DDPKLYDKDLGSALTDTVVAQLDAAWSL$ (서열번호:3089)
DDPKLYDKDLGSALTDTVVAQLDAAWSL (서열번호:3090)
DDPKLYDKDLGSALTDTVVAQLDAATSL$ (서열번호:3091)
DDPKLYDKDLGSALTDTVVAQLDAATSL (서열번호:3092)
DDPKLYDKDLGSALTDTVVAQMDAAWSL$ (서열번호:3093)
DDPKLYDKDLGSALTDTVVAQMDAAWSL (서열번호:3094)
DDPKLYDKDLGSALTDTVVAQMDAATSL$ (서열번호:3095)
DDPKLYDKDLGSALTDTVVAQMDAATSL (서열번호:3096)
DDPKLYDKDLGSALTDTVVGWVDAAWSL$ (서열번호:3097)
DDPKLYDKDLGSALTDTVVGWVDAAWSL (서열번호:3098)
DDPKLYDKDLGSALTDTVVGWVDAATSL$ (서열번호:3099)
DDPKLYDKDLGSALTDTVVGWVDAATSL (서열번호:3100)
DDPKLYDKDLGSALTDTVVGWLDAAWSL$ (서열번호:3101)
DDPKLYDKDLGSALTDTVVGWLDAAWSL (서열번호:3102)
DDPKLYDKDLGSALTDTVVGWLDAATSL$ (서열번호:3103)
DDPKLYDKDLGSALTDTVVGWLDAATSL (서열번호:3104)
DDPKLYDKDLGSALTDTVVGWMDAAWSL$ (서열번호:3105)
DDPKLYDKDLGSALTDTVVGWMDAAWSL (서열번호:3106)
DDPKLYDKDLGSALTDTVVGWMDAATSL$ (서열번호:3107)
DDPKLYDKDLGSALTDTVVGWMDAATSL (서열번호:3108)
DDPKLYDKDLGSALTDTVVGQVDAAWSL$ (서열번호:3109)
DDPKLYDKDLGSALTDTVVGQVDAAWSL (서열번호:3110)
DDPKLYDKDLGSALTDTVVGQVDAATSL$ (서열번호:3111)
DDPKLYDKDLGSALTDTVVGQVDAATSL (서열번호:3112)
DDPKLYDKDLGSALTDTVVGQLDAAWSL$ (서열번호:3113)
DDPKLYDKDLGSALTDTVVGQLDAAWSL (서열번호:3114)
DDPKLYDKDLGSALTDTVVGQLDAATSL$ (서열번호:3115)
DDPKLYDKDLGSALTDTVVGQLDAATSL (서열번호:3116)
DDPKLYDKDLGSALTDTVVGQMDAAWSL$ (서열번호:3117)
DDPKLYDKDLGSALTDTVVGQMDAAWSL (서열번호:3118)
DDPKLYDKDLGSALTDTVVGQMDAATSL$ (서열번호:3119)
DDPKLYDKDLGSALTDTVVGQMDAATSL (서열번호:3120)
DDPKLYDKDLGSALGDWVVAWVDAAWSL$ (서열번호:3121)
DDPKLYDKDLGSALGDWVVAWVDAAWSL (서열번호:3122)
DDPKLYDKDLGSALGDWVVAWVDAATSL$ (서열번호:3123)
DDPKLYDKDLGSALGDWVVAWVDAATSL (서열번호:3124)
DDPKLYDKDLGSALGDWVVAWLDAAWSL$ (서열번호:3125)
DDPKLYDKDLGSALGDWVVAWLDAAWSL (서열번호:3126)
DDPKLYDKDLGSALGDWVVAWLDAATSL$ (서열번호:3127)
DDPKLYDKDLGSALGDWVVAWLDAATSL (서열번호:3128)
DDPKLYDKDLGSALGDWVVAWMDAAWSL$ (서열번호:3129)
DDPKLYDKDLGSALGDWVVAWMDAAWSL (서열번호:3130)
DDPKLYDKDLGSALGDWVVAWMDAATSL$ (서열번호:3131)
DDPKLYDKDLGSALGDWVVAWMDAATSL (서열번호:3132)
DDPKLYDKDLGSALGDWVVAQVDAAWSL$ (서열번호:3133)
DDPKLYDKDLGSALGDWVVAQVDAAWSL (서열번호:3134)
DDPKLYDKDLGSALGDWVVAQVDAATSL$ (서열번호:3135)
DDPKLYDKDLGSALGDWVVAQVDAATSL (서열번호:3136)
DDPKLYDKDLGSALGDWVVAQLDAAWSL$ (서열번호:3137)
DDPKLYDKDLGSALGDWVVAQLDAAWSL (서열번호:3138)
DDPKLYDKDLGSALGDWVVAQLDAATSL$ (서열번호:3139)
DDPKLYDKDLGSALGDWVVAQLDAATSL (서열번호:3140)
DDPKLYDKDLGSALGDWVVAQMDAAWSL$ (서열번호:3141)
DDPKLYDKDLGSALGDWVVAQMDAAWSL (서열번호:3142)
DDPKLYDKDLGSALGDWVVAQMDAATSL$ (서열번호:3143)
DDPKLYDKDLGSALGDWVVAQMDAATSL (서열번호:3144)
DDPKLYDKDLGSALGDWVVGWVDAAWSL$ (서열번호:3145)
DDPKLYDKDLGSALGDWVVGWVDAAWSL (서열번호:3146)
DDPKLYDKDLGSALGDWVVGWVDAATSL$ (서열번호:3147)
DDPKLYDKDLGSALGDWVVGWVDAATSL (서열번호:3148)
DDPKLYDKDLGSALGDWVVGWLDAAWSL$ (서열번호:3149)
DDPKLYDKDLGSALGDWVVGWLDAAWSL (서열번호:3150)
DDPKLYDKDLGSALGDWVVGWLDAATSL$ (서열번호:3151)
DDPKLYDKDLGSALGDWVVGWLDAATSL (서열번호:3152)
DDPKLYDKDLGSALGDWVVGWMDAAWSL$ (서열번호:3153)
DDPKLYDKDLGSALGDWVVGWMDAAWSL (서열번호:3154)
DDPKLYDKDLGSALGDWVVGWMDAATSL$ (서열번호:3155)
DDPKLYDKDLGSALGDWVVGWMDAATSL (서열번호:3156)
DDPKLYDKDLGSALGDWVVGQVDAAWSL$ (서열번호:3157)
DDPKLYDKDLGSALGDWVVGQVDAAWSL (서열번호:3158)
DDPKLYDKDLGSALGDWVVGQVDAATSL$ (서열번호:3159)
DDPKLYDKDLGSALGDWVVGQVDAATSL (서열번호:3160)
DDPKLYDKDLGSALGDWVVGQLDAAWSL$ (서열번호:3161)
DDPKLYDKDLGSALGDWVVGQLDAAWSL (서열번호:3162)
DDPKLYDKDLGSALGDWVVGQLDAATSL$ (서열번호:3163)
DDPKLYDKDLGSALGDWVVGQLDAATSL (서열번호:3164)
DDPKLYDKDLGSALGDWVVGQMDAAWSL$ (서열번호:3165)
DDPKLYDKDLGSALGDWVVGQMDAAWSL (서열번호:3166)
DDPKLYDKDLGSALGDWVVGQMDAATSL$ (서열번호:3167)
DDPKLYDKDLGSALGDWVVGQMDAATSL (서열번호:3168)
DDPKLYDKDLGSALGDTVVAWVDAAWSL$ (서열번호:3169)
DDPKLYDKDLGSALGDTVVAWVDAAWSL (서열번호:3170)
DDPKLYDKDLGSALGDTVVAWVDAATSL$ (서열번호:3171)
DDPKLYDKDLGSALGDTVVAWVDAATSL (서열번호:3172)
DDPKLYDKDLGSALGDTVVAWLDAAWSL$ (서열번호:3173)
DDPKLYDKDLGSALGDTVVAWLDAAWSL (서열번호:3174)
DDPKLYDKDLGSALGDTVVAWLDAATSL$ (서열번호:3175)
DDPKLYDKDLGSALGDTVVAWLDAATSL (서열번호:3176)
DDPKLYDKDLGSALGDTVVAWMDAAWSL$ (서열번호:3177)
DDPKLYDKDLGSALGDTVVAWMDAAWSL (서열번호:3178)
DDPKLYDKDLGSALGDTVVAWMDAATSL$ (서열번호:3179)
DDPKLYDKDLGSALGDTVVAWMDAATSL (서열번호:3180)
DDPKLYDKDLGSALGDTVVAQVDAAWSL$ (서열번호:3181)
DDPKLYDKDLGSALGDTVVAQVDAAWSL (서열번호:3182)
DDPKLYDKDLGSALGDTVVAQVDAATSL$ (서열번호:3183)
DDPKLYDKDLGSALGDTVVAQVDAATSL (서열번호:3184)
DDPKLYDKDLGSALGDTVVAQLDAAWSL$ (서열번호:3185)
DDPKLYDKDLGSALGDTVVAQLDAAWSL (서열번호:3186)
DDPKLYDKDLGSALGDTVVAQLDAATSL$ (서열번호:3187)
DDPKLYDKDLGSALGDTVVAQLDAATSL (서열번호:3188)
DDPKLYDKDLGSALGDTVVAQMDAAWSL$ (서열번호:3189)
DDPKLYDKDLGSALGDTVVAQMDAAWSL (서열번호:3190)
DDPKLYDKDLGSALGDTVVAQMDAATSL$ (서열번호:3191)
DDPKLYDKDLGSALGDTVVAQMDAATSL (서열번호:3192)
DDPKLYDKDLGSALGDTVVGWVDAAWSL$ (서열번호:3193)
DDPKLYDKDLGSALGDTVVGWVDAAWSL (서열번호:3194)
DDPKLYDKDLGSALGDTVVGWVDAATSL$ (서열번호:3195)
DDPKLYDKDLGSALGDTVVGWVDAATSL (서열번호:3196)
DDPKLYDKDLGSALGDTVVGWLDAAWSL$ (서열번호:3197)
DDPKLYDKDLGSALGDTVVGWLDAAWSL (서열번호:3198)
DDPKLYDKDLGSALGDTVVGWLDAATSL$ (서열번호:3199)
DDPKLYDKDLGSALGDTVVGWLDAATSL (서열번호:3200)
DDPKLYDKDLGSALGDTVVGWMDAAWSL$ (서열번호:3201)
DDPKLYDKDLGSALGDTVVGWMDAAWSL (서열번호:3202)
DDPKLYDKDLGSALGDTVVGWMDAATSL$ (서열번호:3203)
DDPKLYDKDLGSALGDTVVGWMDAATSL (서열번호:3204)
DDPKLYDKDLGSALGDTVVGQVDAAWSL$ (서열번호:3205)
DDPKLYDKDLGSALGDTVVGQVDAAWSL (서열번호:3206)
DDPKLYDKDLGSALGDTVVGQVDAATSL$ (서열번호:3207)
DDPKLYDKDLGSALGDTVVGQVDAATSL (서열번호:3208)
DDPKLYDKDLGSALGDTVVGQLDAAWSL$ (서열번호:3209)
DDPKLYDKDLGSALGDTVVGQLDAAWSL (서열번호:3210)
DDPKLYDKDLGSALGDTVVGQLDAATSL$ (서열번호:3211)
DDPKLYDKDLGSALGDTVVGQLDAATSL (서열번호:3212)
DDPKLYDKDLGSALGDTVVGQMDAAWSL$ (서열번호:3213)
DDPKLYDKDLGSALGDTVVGQMDAAWSL (서열번호:3214)
DDPKLYDKDLGSALGDTVVGQMDAATSL$ (서열번호:3215)
DDPKLYDKDLGSALGDTVVGQMDAATSL (서열번호:3216)
DDPKLYDKDLGSAMWDWVVAWVDAAWSL$ (서열번호:3217)
DDPKLYDKDLGSAMWDWVVAWVDAAWSL (서열번호:3218)
DDPKLYDKDLGSAMWDWVVAWVDAATSL$ (서열번호:3219)
DDPKLYDKDLGSAMWDWVVAWVDAATSL (서열번호:3220)
DDPKLYDKDLGSAMWDWVVAWLDAAWSL$ (서열번호:3221)
DDPKLYDKDLGSAMWDWVVAWLDAAWSL (서열번호:3222)
DDPKLYDKDLGSAMWDWVVAWLDAATSL$ (서열번호:3223)
DDPKLYDKDLGSAMWDWVVAWLDAATSL (서열번호:3224)
DDPKLYDKDLGSAMWDWVVAWMDAAWSL$ (서열번호:3225)
DDPKLYDKDLGSAMWDWVVAWMDAAWSL (서열번호:3226)
DDPKLYDKDLGSAMWDWVVAWMDAATSL$ (서열번호:3227)
DDPKLYDKDLGSAMWDWVVAWMDAATSL (서열번호:3228)
DDPKLYDKDLGSAMWDWVVAQVDAAWSL$ (서열번호:3229)
DDPKLYDKDLGSAMWDWVVAQVDAAWSL (서열번호:3230)
DDPKLYDKDLGSAMWDWVVAQVDAATSL$ (서열번호:3231)
DDPKLYDKDLGSAMWDWVVAQVDAATSL (서열번호:3232)
DDPKLYDKDLGSAMWDWVVAQLDAAWSL$ (서열번호:3233)
DDPKLYDKDLGSAMWDWVVAQLDAAWSL (서열번호:3234)
DDPKLYDKDLGSAMWDWVVAQLDAATSL$ (서열번호:3235)
DDPKLYDKDLGSAMWDWVVAQLDAATSL (서열번호:3236)
DDPKLYDKDLGSAMWDWVVAQMDAAWSL$ (서열번호:3237)
DDPKLYDKDLGSAMWDWVVAQMDAAWSL (서열번호:3238)
DDPKLYDKDLGSAMWDWVVAQMDAATSL$ (서열번호:3239)
DDPKLYDKDLGSAMWDWVVAQMDAATSL (서열번호:3240)
DDPKLYDKDLGSAMWDWVVGWVDAAWSL$ (서열번호:3241)
DDPKLYDKDLGSAMWDWVVGWVDAAWSL (서열번호:3242)
DDPKLYDKDLGSAMWDWVVGWVDAATSL$ (서열번호:3243)
DDPKLYDKDLGSAMWDWVVGWVDAATSL (서열번호:3244)
DDPKLYDKDLGSAMWDWVVGWLDAAWSL$ (서열번호:3245)
DDPKLYDKDLGSAMWDWVVGWLDAAWSL (서열번호:3246)
DDPKLYDKDLGSAMWDWVVGWLDAATSL$ (서열번호:3247)
DDPKLYDKDLGSAMWDWVVGWLDAATSL (서열번호:3248)
DDPKLYDKDLGSAMWDWVVGWMDAAWSL$ (서열번호:3249)
DDPKLYDKDLGSAMWDWVVGWMDAAWSL (서열번호:3250)
DDPKLYDKDLGSAMWDWVVGWMDAATSL$ (서열번호:3251)
DDPKLYDKDLGSAMWDWVVGWMDAATSL (서열번호:3252)
DDPKLYDKDLGSAMWDWVVGQVDAAWSL$ (서열번호:3253)
DDPKLYDKDLGSAMWDWVVGQVDAAWSL (서열번호:3254)
DDPKLYDKDLGSAMWDWVVGQVDAATSL$ (서열번호:3255)
DDPKLYDKDLGSAMWDWVVGQVDAATSL (서열번호:3256)
DDPKLYDKDLGSAMWDWVVGQLDAAWSL$ (서열번호:3257)
DDPKLYDKDLGSAMWDWVVGQLDAAWSL (서열번호:3258)
DDPKLYDKDLGSAMWDWVVGQLDAATSL$ (서열번호:3259)
DDPKLYDKDLGSAMWDWVVGQLDAATSL (서열번호:3260)
DDPKLYDKDLGSAMWDWVVGQMDAAWSL$ (서열번호:3261)
DDPKLYDKDLGSAMWDWVVGQMDAAWSL (서열번호:3262)
DDPKLYDKDLGSAMWDWVVGQMDAATSL$ (서열번호:3263)
DDPKLYDKDLGSAMWDWVVGQMDAATSL (서열번호:3264)
DDPKLYDKDLGSAMWDTVVAWVDAAWSL$ (서열번호:3265)
DDPKLYDKDLGSAMWDTVVAWVDAAWSL (서열번호:3266)
DDPKLYDKDLGSAMWDTVVAWVDAATSL$ (서열번호:3267)
DDPKLYDKDLGSAMWDTVVAWVDAATSL (서열번호:3268)
DDPKLYDKDLGSAMWDTVVAWLDAAWSL$ (서열번호:3269)
DDPKLYDKDLGSAMWDTVVAWLDAAWSL (서열번호:3270)
DDPKLYDKDLGSAMWDTVVAWLDAATSL$ (서열번호:3271)
DDPKLYDKDLGSAMWDTVVAWLDAATSL (서열번호:3272)
DDPKLYDKDLGSAMWDTVVAWMDAAWSL$ (서열번호:3273)
DDPKLYDKDLGSAMWDTVVAWMDAAWSL (서열번호:3274)
DDPKLYDKDLGSAMWDTVVAWMDAATSL$ (서열번호:3275)
DDPKLYDKDLGSAMWDTVVAWMDAATSL (서열번호:3276)
DDPKLYDKDLGSAMWDTVVAQVDAAWSL$ (서열번호:3277)
DDPKLYDKDLGSAMWDTVVAQVDAAWSL (서열번호:3278)
DDPKLYDKDLGSAMWDTVVAQVDAATSL$ (서열번호:3279)
DDPKLYDKDLGSAMWDTVVAQVDAATSL (서열번호:3280)
DDPKLYDKDLGSAMWDTVVAQLDAAWSL$ (서열번호:3281)
DDPKLYDKDLGSAMWDTVVAQLDAAWSL (서열번호:3282)
DDPKLYDKDLGSAMWDTVVAQLDAATSL$ (서열번호:3283)
DDPKLYDKDLGSAMWDTVVAQLDAATSL (서열번호:3284)
DDPKLYDKDLGSAMWDTVVAQMDAAWSL$ (서열번호:3285)
DDPKLYDKDLGSAMWDTVVAQMDAAWSL (서열번호:3286)
DDPKLYDKDLGSAMWDTVVAQMDAATSL$ (서열번호:3287)
DDPKLYDKDLGSAMWDTVVAQMDAATSL (서열번호:3288)
DDPKLYDKDLGSAMWDTVVGWVDAAWSL$ (서열번호:3289)
DDPKLYDKDLGSAMWDTVVGWVDAAWSL (서열번호:3290)
DDPKLYDKDLGSAMWDTVVGWVDAATSL$ (서열번호:3291)
DDPKLYDKDLGSAMWDTVVGWVDAATSL (서열번호:3292)
DDPKLYDKDLGSAMWDTVVGWLDAAWSL$ (서열번호:3293)
DDPKLYDKDLGSAMWDTVVGWLDAAWSL (서열번호:3294)
DDPKLYDKDLGSAMWDTVVGWLDAATSL$ (서열번호:3295)
DDPKLYDKDLGSAMWDTVVGWLDAATSL (서열번호:3296)
DDPKLYDKDLGSAMWDTVVGWMDAAWSL$ (서열번호:3297)
DDPKLYDKDLGSAMWDTVVGWMDAAWSL (서열번호:3298)
DDPKLYDKDLGSAMWDTVVGWMDAATSL$ (서열번호:3299)
DDPKLYDKDLGSAMWDTVVGWMDAATSL (서열번호:3300)
DDPKLYDKDLGSAMWDTVVGQVDAAWSL$ (서열번호:3301)
DDPKLYDKDLGSAMWDTVVGQVDAAWSL (서열번호:3302)
DDPKLYDKDLGSAMWDTVVGQVDAATSL$ (서열번호:3303)
DDPKLYDKDLGSAMWDTVVGQVDAATSL (서열번호:3304)
DDPKLYDKDLGSAMWDTVVGQLDAAWSL$ (서열번호:3305)
DDPKLYDKDLGSAMWDTVVGQLDAAWSL (서열번호:3306)
DDPKLYDKDLGSAMWDTVVGQLDAATSL$ (서열번호:3307)
DDPKLYDKDLGSAMWDTVVGQLDAATSL (서열번호:3308)
DDPKLYDKDLGSAMWDTVVGQMDAAWSL$ (서열번호:3309)
DDPKLYDKDLGSAMWDTVVGQMDAAWSL (서열번호:3310)
DDPKLYDKDLGSAMWDTVVGQMDAATSL$ (서열번호:3311)
DDPKLYDKDLGSAMWDTVVGQMDAATSL (서열번호:3312)
DDPKLYDKDLGSAMTDWVVAWVDAAWSL$ (서열번호:3313)
DDPKLYDKDLGSAMTDWVVAWVDAAWSL (서열번호:3314)
DDPKLYDKDLGSAMTDWVVAWVDAATSL$ (서열번호:3315)
DDPKLYDKDLGSAMTDWVVAWVDAATSL (서열번호:3316)
DDPKLYDKDLGSAMTDWVVAWLDAAWSL$ (서열번호:3317)
DDPKLYDKDLGSAMTDWVVAWLDAAWSL (서열번호:3318)
DDPKLYDKDLGSAMTDWVVAWLDAATSL$ (서열번호:3319)
DDPKLYDKDLGSAMTDWVVAWLDAATSL (서열번호:3320)
DDPKLYDKDLGSAMTDWVVAWMDAAWSL$ (서열번호:3321)
DDPKLYDKDLGSAMTDWVVAWMDAAWSL (서열번호:3322)
DDPKLYDKDLGSAMTDWVVAWMDAATSL$ (서열번호:3323)
DDPKLYDKDLGSAMTDWVVAWMDAATSL (서열번호:3324)
DDPKLYDKDLGSAMTDWVVAQVDAAWSL$ (서열번호:3325)
DDPKLYDKDLGSAMTDWVVAQVDAAWSL (서열번호:3326)
DDPKLYDKDLGSAMTDWVVAQVDAATSL$ (서열번호:3327)
DDPKLYDKDLGSAMTDWVVAQVDAATSL (서열번호:3328)
DDPKLYDKDLGSAMTDWVVAQLDAAWSL$ (서열번호:3329)
DDPKLYDKDLGSAMTDWVVAQLDAAWSL (서열번호:3330)
DDPKLYDKDLGSAMTDWVVAQLDAATSL$ (서열번호:3331)
DDPKLYDKDLGSAMTDWVVAQLDAATSL (서열번호:3332)
DDPKLYDKDLGSAMTDWVVAQMDAAWSL$ (서열번호:3333)
DDPKLYDKDLGSAMTDWVVAQMDAAWSL (서열번호:3334)
DDPKLYDKDLGSAMTDWVVAQMDAATSL$ (서열번호:3335)
DDPKLYDKDLGSAMTDWVVAQMDAATSL (서열번호:3336)
DDPKLYDKDLGSAMTDWVVGWVDAAWSL$ (서열번호:3337)
DDPKLYDKDLGSAMTDWVVGWVDAAWSL (서열번호:3338)
DDPKLYDKDLGSAMTDWVVGWVDAATSL$ (서열번호:3339)
DDPKLYDKDLGSAMTDWVVGWVDAATSL (서열번호:3340)
DDPKLYDKDLGSAMTDWVVGWLDAAWSL$ (서열번호:3341)
DDPKLYDKDLGSAMTDWVVGWLDAAWSL (서열번호:3342)
DDPKLYDKDLGSAMTDWVVGWLDAATSL$ (서열번호:3343)
DDPKLYDKDLGSAMTDWVVGWLDAATSL (서열번호:3344)
DDPKLYDKDLGSAMTDWVVGWMDAAWSL$ (서열번호:3345)
DDPKLYDKDLGSAMTDWVVGWMDAAWSL (서열번호:3346)
DDPKLYDKDLGSAMTDWVVGWMDAATSL$ (서열번호:3347)
DDPKLYDKDLGSAMTDWVVGWMDAATSL (서열번호:3348)
DDPKLYDKDLGSAMTDWVVGQVDAAWSL$ (서열번호:3349)
DDPKLYDKDLGSAMTDWVVGQVDAAWSL (서열번호:3350)
DDPKLYDKDLGSAMTDWVVGQVDAATSL$ (서열번호:3351)
DDPKLYDKDLGSAMTDWVVGQVDAATSL (서열번호:3352)
DDPKLYDKDLGSAMTDWVVGQLDAAWSL$ (서열번호:3353)
DDPKLYDKDLGSAMTDWVVGQLDAAWSL (서열번호:3354)
DDPKLYDKDLGSAMTDWVVGQLDAATSL$ (서열번호:3355)
DDPKLYDKDLGSAMTDWVVGQLDAATSL (서열번호:3356)
DDPKLYDKDLGSAMTDWVVGQMDAAWSL$ (서열번호:3357)
DDPKLYDKDLGSAMTDWVVGQMDAAWSL (서열번호:3358)
DDPKLYDKDLGSAMTDWVVGQMDAATSL$ (서열번호:3359)
DDPKLYDKDLGSAMTDWVVGQMDAATSL (서열번호:3360)
DDPKLYDKDLGSAMTDTVVAWVDAAWSL$ (서열번호:3361)
DDPKLYDKDLGSAMTDTVVAWVDAAWSL (서열번호:3362)
DDPKLYDKDLGSAMTDTVVAWVDAATSL$ (서열번호:3363)
DDPKLYDKDLGSAMTDTVVAWVDAATSL (서열번호:3364)
DDPKLYDKDLGSAMTDTVVAWLDAAWSL$ (서열번호:3365)
DDPKLYDKDLGSAMTDTVVAWLDAAWSL (서열번호:3366)
DDPKLYDKDLGSAMTDTVVAWLDAATSL$ (서열번호:3367)
DDPKLYDKDLGSAMTDTVVAWLDAATSL (서열번호:3368)
DDPKLYDKDLGSAMTDTVVAWMDAAWSL$ (서열번호:3369)
DDPKLYDKDLGSAMTDTVVAWMDAAWSL (서열번호:3370)
DDPKLYDKDLGSAMTDTVVAWMDAATSL$ (서열번호:3371)
DDPKLYDKDLGSAMTDTVVAWMDAATSL (서열번호:3372)
DDPKLYDKDLGSAMTDTVVAQVDAAWSL$ (서열번호:3373)
DDPKLYDKDLGSAMTDTVVAQVDAAWSL (서열번호:3374)
DDPKLYDKDLGSAMTDTVVAQVDAATSL$ (서열번호:3375)
DDPKLYDKDLGSAMTDTVVAQVDAATSL (서열번호:3376)
DDPKLYDKDLGSAMTDTVVAQLDAAWSL$ (서열번호:3377)
DDPKLYDKDLGSAMTDTVVAQLDAAWSL (서열번호:3378)
DDPKLYDKDLGSAMTDTVVAQLDAATSL$ (서열번호:3379)
DDPKLYDKDLGSAMTDTVVAQLDAATSL (서열번호:3380)
DDPKLYDKDLGSAMTDTVVAQMDAAWSL$ (서열번호:3381)
DDPKLYDKDLGSAMTDTVVAQMDAAWSL (서열번호:3382)
DDPKLYDKDLGSAMTDTVVAQMDAATSL$ (서열번호:3383)
DDPKLYDKDLGSAMTDTVVAQMDAATSL (서열번호:3384)
DDPKLYDKDLGSAMTDTVVGWVDAAWSL$ (서열번호:3385)
DDPKLYDKDLGSAMTDTVVGWVDAAWSL (서열번호:3386)
DDPKLYDKDLGSAMTDTVVGWVDAATSL$ (서열번호:3387)
DDPKLYDKDLGSAMTDTVVGWVDAATSL (서열번호:3388)
DDPKLYDKDLGSAMTDTVVGWLDAAWSL$ (서열번호:3389)
DDPKLYDKDLGSAMTDTVVGWLDAAWSL (서열번호:3390)
DDPKLYDKDLGSAMTDTVVGWLDAATSL$ (서열번호:3391)
DDPKLYDKDLGSAMTDTVVGWLDAATSL (서열번호:3392)
DDPKLYDKDLGSAMTDTVVGWMDAAWSL$ (서열번호:3393)
DDPKLYDKDLGSAMTDTVVGWMDAAWSL (서열번호:3394)
DDPKLYDKDLGSAMTDTVVGWMDAATSL$ (서열번호:3395)
DDPKLYDKDLGSAMTDTVVGWMDAATSL (서열번호:3396)
DDPKLYDKDLGSAMTDTVVGQVDAAWSL$ (서열번호:3397)
DDPKLYDKDLGSAMTDTVVGQVDAAWSL (서열번호:3398)
DDPKLYDKDLGSAMTDTVVGQVDAATSL$ (서열번호:3399)
DDPKLYDKDLGSAMTDTVVGQVDAATSL (서열번호:3400)
DDPKLYDKDLGSAMTDTVVGQLDAAWSL$ (서열번호:3401)
DDPKLYDKDLGSAMTDTVVGQLDAAWSL (서열번호:3402)
DDPKLYDKDLGSAMTDTVVGQLDAATSL$ (서열번호:3403)
DDPKLYDKDLGSAMTDTVVGQLDAATSL (서열번호:3404)
DDPKLYDKDLGSAMTDTVVGQMDAAWSL$ (서열번호:3405)
DDPKLYDKDLGSAMTDTVVGQMDAAWSL (서열번호:3406)
DDPKLYDKDLGSAMTDTVVGQMDAATSL$ (서열번호:3407)
DDPKLYDKDLGSAMTDTVVGQMDAATSL (서열번호:3408)
DDPKLYDKDLGSAMGDWVVAWVDAAWSL$ (서열번호:3409)
DDPKLYDKDLGSAMGDWVVAWVDAAWSL (서열번호:3410)
DDPKLYDKDLGSAMGDWVVAWVDAATSL$ (서열번호:3411)
DDPKLYDKDLGSAMGDWVVAWVDAATSL (서열번호:3412)
DDPKLYDKDLGSAMGDWVVAWLDAAWSL$ (서열번호:3413)
DDPKLYDKDLGSAMGDWVVAWLDAAWSL (서열번호:3414)
DDPKLYDKDLGSAMGDWVVAWLDAATSL$ (서열번호:3415)
DDPKLYDKDLGSAMGDWVVAWLDAATSL (서열번호:3416)
DDPKLYDKDLGSAMGDWVVAWMDAAWSL$ (서열번호:3417)
DDPKLYDKDLGSAMGDWVVAWMDAAWSL (서열번호:3418)
DDPKLYDKDLGSAMGDWVVAWMDAATSL$ (서열번호:3419)
DDPKLYDKDLGSAMGDWVVAWMDAATSL (서열번호:3420)
DDPKLYDKDLGSAMGDWVVAQVDAAWSL$ (서열번호:3421)
DDPKLYDKDLGSAMGDWVVAQVDAAWSL (서열번호:3422)
DDPKLYDKDLGSAMGDWVVAQVDAATSL$ (서열번호:3423)
DDPKLYDKDLGSAMGDWVVAQVDAATSL (서열번호:3424)
DDPKLYDKDLGSAMGDWVVAQLDAAWSL$ (서열번호:3425)
DDPKLYDKDLGSAMGDWVVAQLDAAWSL (서열번호:3426)
DDPKLYDKDLGSAMGDWVVAQLDAATSL$ (서열번호:3427)
DDPKLYDKDLGSAMGDWVVAQLDAATSL (서열번호:3428)
DDPKLYDKDLGSAMGDWVVAQMDAAWSL$ (서열번호:3429)
DDPKLYDKDLGSAMGDWVVAQMDAAWSL (서열번호:3430)
DDPKLYDKDLGSAMGDWVVAQMDAATSL$ (서열번호:3431)
DDPKLYDKDLGSAMGDWVVAQMDAATSL (서열번호:3432)
DDPKLYDKDLGSAMGDWVVGWVDAAWSL$ (서열번호:3433)
DDPKLYDKDLGSAMGDWVVGWVDAAWSL (서열번호:3434)
DDPKLYDKDLGSAMGDWVVGWVDAATSL$ (서열번호:3435)
DDPKLYDKDLGSAMGDWVVGWVDAATSL (서열번호:3436)
DDPKLYDKDLGSAMGDWVVGWLDAAWSL$ (서열번호:3437)
DDPKLYDKDLGSAMGDWVVGWLDAAWSL (서열번호:3438)
DDPKLYDKDLGSAMGDWVVGWLDAATSL$ (서열번호:3439)
DDPKLYDKDLGSAMGDWVVGWLDAATSL (서열번호:3440)
DDPKLYDKDLGSAMGDWVVGWMDAAWSL$ (서열번호:3441)
DDPKLYDKDLGSAMGDWVVGWMDAAWSL (서열번호:3442)
DDPKLYDKDLGSAMGDWVVGWMDAATSL$ (서열번호:3443)
DDPKLYDKDLGSAMGDWVVGWMDAATSL (서열번호:3444)
DDPKLYDKDLGSAMGDWVVGQVDAAWSL$ (서열번호:3445)
DDPKLYDKDLGSAMGDWVVGQVDAAWSL (서열번호:3446)
DDPKLYDKDLGSAMGDWVVGQVDAATSL$ (서열번호:3447)
DDPKLYDKDLGSAMGDWVVGQVDAATSL (서열번호:3448)
DDPKLYDKDLGSAMGDWVVGQLDAAWSL$ (서열번호:3449)
DDPKLYDKDLGSAMGDWVVGQLDAAWSL (서열번호:3450)
DDPKLYDKDLGSAMGDWVVGQLDAATSL$ (서열번호:3451)
DDPKLYDKDLGSAMGDWVVGQLDAATSL (서열번호:3452)
DDPKLYDKDLGSAMGDWVVGQMDAAWSL$ (서열번호:3453)
DDPKLYDKDLGSAMGDWVVGQMDAAWSL (서열번호:3454)
DDPKLYDKDLGSAMGDWVVGQMDAATSL$ (서열번호:3455)
DDPKLYDKDLGSAMGDWVVGQMDAATSL (서열번호:3456)
DDPKLYDKDLGSAMGDTVVAWVDAAWSL$ (서열번호:3457)
DDPKLYDKDLGSAMGDTVVAWVDAAWSL (서열번호:3458)
DDPKLYDKDLGSAMGDTVVAWVDAATSL$ (서열번호:3459)
DDPKLYDKDLGSAMGDTVVAWVDAATSL (서열번호:3460)
DDPKLYDKDLGSAMGDTVVAWLDAAWSL$ (서열번호:3461)
DDPKLYDKDLGSAMGDTVVAWLDAAWSL (서열번호:3462)
DDPKLYDKDLGSAMGDTVVAWLDAATSL$ (서열번호:3463)
DDPKLYDKDLGSAMGDTVVAWLDAATSL (서열번호:3464)
DDPKLYDKDLGSAMGDTVVAWMDAAWSL$ (서열번호:3465)
DDPKLYDKDLGSAMGDTVVAWMDAAWSL (서열번호:3466)
DDPKLYDKDLGSAMGDTVVAWMDAATSL$ (서열번호:3467)
DDPKLYDKDLGSAMGDTVVAWMDAATSL (서열번호:3468)
DDPKLYDKDLGSAMGDTVVAQVDAAWSL$ (서열번호:3469)
DDPKLYDKDLGSAMGDTVVAQVDAAWSL (서열번호:3470)
DDPKLYDKDLGSAMGDTVVAQVDAATSL$ (서열번호:3471)
DDPKLYDKDLGSAMGDTVVAQVDAATSL (서열번호:3472)
DDPKLYDKDLGSAMGDTVVAQLDAAWSL$ (서열번호:3473)
DDPKLYDKDLGSAMGDTVVAQLDAAWSL (서열번호:3474)
DDPKLYDKDLGSAMGDTVVAQLDAATSL$ (서열번호:3475)
DDPKLYDKDLGSAMGDTVVAQLDAATSL (서열번호:3476)
DDPKLYDKDLGSAMGDTVVAQMDAAWSL$ (서열번호:3477)
DDPKLYDKDLGSAMGDTVVAQMDAAWSL (서열번호:3478)
DDPKLYDKDLGSAMGDTVVAQMDAATSL$ (서열번호:3479)
DDPKLYDKDLGSAMGDTVVAQMDAATSL (서열번호:3480)
DDPKLYDKDLGSAMGDTVVGWVDAAWSL$ (서열번호:3481)
DDPKLYDKDLGSAMGDTVVGWVDAAWSL (서열번호:3482)
DDPKLYDKDLGSAMGDTVVGWVDAATSL$ (서열번호:3483)
DDPKLYDKDLGSAMGDTVVGWVDAATSL (서열번호:3484)
DDPKLYDKDLGSAMGDTVVGWLDAAWSL$ (서열번호:3485)
DDPKLYDKDLGSAMGDTVVGWLDAAWSL (서열번호:3486)
DDPKLYDKDLGSAMGDTVVGWLDAATSL$ (서열번호:3487)
DDPKLYDKDLGSAMGDTVVGWLDAATSL (서열번호:3488)
DDPKLYDKDLGSAMGDTVVGWMDAAWSL$ (서열번호:3489)
DDPKLYDKDLGSAMGDTVVGWMDAAWSL (서열번호:3490)
DDPKLYDKDLGSAMGDTVVGWMDAATSL$ (서열번호:3491)
DDPKLYDKDLGSAMGDTVVGWMDAATSL (서열번호:3492)
DDPKLYDKDLGSAMGDTVVGQVDAAWSL$ (서열번호:3493)
DDPKLYDKDLGSAMGDTVVGQVDAAWSL (서열번호:3494)
DDPKLYDKDLGSAMGDTVVGQVDAATSL$ (서열번호:3495)
DDPKLYDKDLGSAMGDTVVGQVDAATSL (서열번호:3496)
DDPKLYDKDLGSAMGDTVVGQLDAAWSL$ (서열번호:3497)
DDPKLYDKDLGSAMGDTVVGQLDAAWSL (서열번호:3498)
DDPKLYDKDLGSAMGDTVVGQLDAATSL$ (서열번호:3499)
DDPKLYDKDLGSAMGDTVVGQLDAATSL (서열번호:3500)
DDPKLYDKDLGSAMGDTVVGQMDAAWSL$ (서열번호:3501)
DDPKLYDKDLGSAMGDTVVGQMDAAWSL (서열번호:3502)
DDPKLYDKDLGSAMGDTVVGQMDAATSL$ (서열번호:3503)
DDPKLYDKDLGSAMGDTVVGQMDAATSL (서열번호:3504)
페길화( PEGylation )
치료 및 진단에 중요한 약물에 PEG를 공유 결합시키는 것은 생체 내에서 약물의 혈장 반감기를 연장시키고/연장시키거나 이들의 면역원성 및 항원성을 감소시킨다(Harris 및 Chess, Nature Revuews Drug Discovery 2:214-221 (2003)). 예를 들어, PGG 결합은 수많은 치료용 단백질 중에 인터루킨(Kaufman 등, J. Biol. Chem. 263:15064 (1988); Tsutsumi 등, J. Controlled Release 33:447 (1995)), 인터페론(Kita 등, Drug Des. Delivery 6:157 (1990)), 카탈라아제(Abuchowski 등, J. Biol. Chem. 252:3582 (1977)), 과산소디스뮤타아제(superoxide dismutase)(Beauchamp 등, Anal. Biochem. 131 :25 (1983)), 및 아데노신 아미노기 이탈 효소(Chen 등, Biochem. Biophys. Acta 660:293 (1981))를 포함하는 치료용 단백질의 약물 동력학 성질을 개선했다. FDA는 PEG를 주사 가능한 제형, 국부 제형, 직장 제형 그리고 비강 제형을 포함하는 음식, 화장품 및 약제의 담체 또는 기본 재료로서 사용을 승인했다. PEG는 약간의 독성을 보이고, 신장(PEGs < 30 kDa) 또는 배설물(PEGs > 20 kDa) 중 어느 하나에 의해 온전하게 신체로부터 제거된다. PEG는 물에 매우 잘 용해된다.
치료용 펩타이드의 페길화는 신장의 한외 여과를 줄여서 신체로부터 약물의 배출을 줄임으로써 환자의 혈류 중의 펩타이드 반감기를 증가시키는데에 사용될 수 있다. 전하 차폐(charge masking)는 신장의 삼투에 영향을 줄 수 있다. 전하 차폐는 단백질의 이온 가능한 작용기, 즉 아민 또는 카복실기의 파라화학적(parachemical) 변형의 결과일 수 있다. 특히, 단백질-PGG 유도체를 생산하기 위한 가장 일반적인 절차는 단백질 아미노기를 양전하의 간접손실을 갖는 아미드로 전환하는 것을 수반하고, 이는 단백질 한외여과를 변화시킬 수 있다. 음이온성 고분자(macromolecule)는 중성 또는 양이온 고분자보다 더 느리게 신장의 한외 여과에 의해 제거되는 것으로 밝혀졌기 때문에, 아미노기에 결합하는 PEG는 혈류 중의 페길화된 펩타이드의 영구성을 연장시킬 것으로 예상될 수 있다.
또한, 분자 크기 및 구형의 한외 여과는 치료용 펩타이드의 신장의 한외 여과에 영향을 미칠 수 있다. 자생의 구형 단백질의 신장 배출을 위한 분자량 차단(cut off)은 약 70 kDa으로 고려되며, 이런 분자량은 혈청 알부민의 분자량과 비슷하다. 따라서, 70 kDa을 초과하는 분자량을 갖는 단백질은 신장의 한외 여과보다 간에서 흡수, 단백질 가수 분해에 의한 소화 및 면역계에 의한 제거와 같은 경로에 의하여 신체로부터 주로 배출된다. 그러므로, 페길화에 의한 치료용 펩타이드의 크기를 증가시키는 것은 펩타이드가 환자의 혈류를 형성하도록 신장의 한외 여과를 감소시킬 수 있다.
게다가, 치료용 펩타이드의 페길화는 펩타이드의 면역원성을 감소시킬 뿐만 아니라 단백질 분해 효소, 식작용 세포 및 치료용 펩타이드에 직접 접촉을 요구하는 다른 인자로부터의 펩타이드를 보호할 수 있다. 특히, 분지된 PEG의 우산모양의 구조는 접근하는 단백질 분해 효소, 항체, 식세포 등에 대하여 선형 PGG 보다 더 나은 보호를 제공한다고 밝혀졌다(Caliceti 및 Veronese, Adv. Drug. Deliv. Rev. 55:1261-12778 (2003)).
일부 실시예에서, 큐프레독신 유래 펩타이드는 시스테인 분자에 공유결합되는 하나 이상의 PGG 분자를 갖도록 변형된다. 공유결합은 PGG 분자로부터 큐프레독신 유래 펩타이드로 직접적인 공유결합을 반드시 필요로 하는 것은 아니지만, 하나 이상의 링커 분자에 공유결합되게 하여, 서로 간에 및/또는 큐프레독신 유래 펩타이드에 공유결합된다. 일부 실시예에서, 큐프레독신 유래 펩타이드는 위치 특이적 페길화를 갖는다. 구체적인 실시예에서, PGG 분자는 녹농균 아주린(서열번호:1)의 3번, 26번 및/또는 112번의 시스테인 잔기에 공유결합될 수 있다. 다른 실시예에서, 하나 이상의 시스테인 잔기는 큐프레독신 유래 펩타이드로 치환될 수 있고, 페길화된다. 일부 실시예에서, 큐프레독신 유래 펩타이드를 페길화하는 방법은 그 중에서도 NHS, 환원적 아미노화, 말리미드(malimid) 또는 에폭시화일 수 있다. 다른 실시예에서, 큐프레독신 유래 펩타이드는 하나 이상의 리신, 시스테인, 히스티딘, 아르기닌, 아스파르트산, 글루탐산, 세린, 트레오닌 또는 티로신 상에 페길화될 수 있거나, N-말단 아미노기 또는 C-말단 카복실산 상에 페길화될 수 있다. 더 구체적인 실시예에서, 큐프레독신 유래 펩타이드는 하나 이상의 리신 또는 N-말단 아미노기 상에서 페길화될 수 있다. 다른 실시예에서, 하나 이상의 리신, 시스테인, 히스티딘, 아르기닌, 아스파르트산, 글루탐산, 세린, 트레오닌 또는 티로신 잔기는 큐프레독신 유래 펩타이드로 치환되고 페길화된다. 다른 실시예에서, 큐프레독신 유래 펩타이드는 하나 이상의 아미노기 상에서 페길화될 수 있다. 다른 실시예에서, 큐프레독신 유래 펩타이드는 무작위, 비-위치 특이적 방식으로 페길화될 수 있다. 일부 실시예에서, 큐프레독신 유래 펩타이드는 약 200 Da 내지 약 100,000 Da, 약 2,000 Da 내지 약 20,000 Da, 또는 약 2,000 Da 내지 약 5,000 Da의 PEG-기반 폴리머 평균 분자량을 가질 수 있다. 다른 실시예에서, 큐프레독신 유래 펩타이드는 분지된 하나 이상의 PEG, 구체적으로 약 50 kDa인 분지된 PGG 분자로 구성될 수 있다. 다른 실시예에서, 큐프레독신 유래 펩타이드는 하나 이상의 선형 PEG 분자, 구체적으로 약 5 kDa인 선형 PEG 분자를 포함할 수 있다.
큐프레독신
"큐프레독신"은 예를 들어, 박테리아의 산화 환원 반응 또는 광합성에 참여하는 전자 전달 성질(10-20 kDa)을 갖는 단백질을 함유하는 작은 청색 구리이다. 구리 이온은 오직 단백질 기질에 의해 결합된다. 구리 주변에 있는 두 개의 히스티딘 및 하나의 시스테인 리간드에 대해 특별히 비틀어진 삼각형 배열은 금속 부위 및 강렬한 청색의 매우 독특한 전기적 성질의 증가를 가져온다. 다수의 큐프레독신은 중간 내지 고 해상도로 결정학적으로 특징되었다. 큐프레독신은 아주린, 플라스토시아닌, 루스티시아닌, 슈도아주린, 오라시아닌 및 아주린 유사 단백질을 포함한다. 본 명세서에서 사용된 용어 "큐프레독신"은 구리 원자가 없는 단백질 형태를 포함할 뿐만 아니라 단백질을 함유하는 구리를 포함한다.
아주린
아주린은 식물과 어떤 박테리아에서 전자 전달에 수반되는 큐프레독신과에 속하는 128개의 아미노산 잔기의 단백질을 함유하는 구리이다. 상기 아주린은 녹농균(서열번호:1)("wt-아주린"), 알칼리제네스 자일로속시던스(A. xylosoxidans) 및 알칼리제네스 데니트리피칸스(A. denitrificans)로부터 유래된 것을 포함한다(Murphy 등, J. MoI. Biol. 315:859-871 (2002)). 아주린들 간의 서열 상동성이 60 내지 90 %로 각기 다름에도 불구하고, 분자들 간의 구조적 상동성은 높다. 모든 아주린은 그릭 키 모티프(Greek key motif)를 갖는 β-샌드위치 특징을 갖고, 하나의 구리 원자는 항상 단백질의 동일한 영역에 배치된다. 게다가, 아주린은 구리 영역을 둘러싸는 본질적으로 중성인 소수성 패치를 지닌다. Id.
플라스토시아닌
플라스토시아닌은 진핵 실물 및 시아노박테리아군에서 발견되는 큐프레독신이다. 이들은 분자당 한 분자의 구리를 함유하고, 산화된 형태에서 청색이다. 그들은 엽록체에서 발생하며, 전자 담체로 기능한다. 1978년 포플러 플라스토시아닌의 구조의 확인으로 인하여, 해조류의 구조() 및 식물() 플라스토시아닌은 결정학적으로 또는 NMR 방법으로 확인되었고, 포플러 구조는 1.33 Å 해상도로 개량되었다. 서열번호:2는 시아노박테리아 포르미디움 라미노섬으로부터 유래된 플라스토시아닌의 아미노산 서열을 보여준다.
해조류와 관다발 식물의 플라스토시아닌들 중의 서열 차이에도 불구하고(예, 클라미도모나스 및 포플러 단백질 간의 62 % 서열 동일성), 3차원 구조는 보존된다(예, 클라미도모나스 및 포플러 단백질 간의 C-알파 위치에서 0.76 Å rms 편차). 구조적 특징은 여덟 가닥으로 역평행한 β 통형의 한쪽 말단, 확연한 음성 패치 및 평평한 소수성 표면에서 비틀어진 사면체 구리 결합 부위를 포함한다. 구리 부위는 전자 전달 기능을 위해 최적화되고, 음성 소수성 패치는 생리학적 반응 파트너의 인식에 수반되도록 제안된다. 화학적 변형, 가교결합 및 부위 특이적 돌연변이 생성 실험은 시토크롬 f와 결합 상호작용에 음성 소수성 패치의 중요성을 확인했고, 플라스토시아닌에서 두 개의 기능상 중요한 전자 전달 경로의 모델을 입증했다. 추정되는 전자 전달 경로는 비교적 짧고(약 4 Å) 소수성 패치에서 용매에 노출된 구리 리간드 His-87을 포함하는 반면에, 다른 전자 전달 경로는 더 길고(약 12 내지 15 Å) 음성 패치에서 거의 보존된 잔기 Tyr-83을 포함한다(Redinbo 등, J. Bioenerg. Biomembr. 26(l):49-66 (1994)).
루스티시아닌
루스티시아닌은 티오바실러스로부터 얻은 단일쇄 폴리펩타이드를 함유하는 청색 구리이다. 티오바실러스 페로옥시단스(서열번호:3)로부터 유래된 매우 안정하고 고도로 산화되는 큐프레독신 루스티시아닌의 산화된 형태의 X-선 결정 구조는 다파장 변칙 회절(multiwavelength anomalous diffraction)에 의해 확인 되었고, 1.9 Å 해상도로 개량되었다. 루스티시아닌은 6개 가닥의 β-시트 및 7개 가닥의 β-시트로 구성되는 중심 β-샌드위치 접힘으로 구성된다. 다른 큐프레독신과 같이, 구리 이온은 비틀어진 사면체로 배열된 네 개의 보존된 잔기 무리(His85, Cys138, His143, Met148)에 의해 배위된다(Walter 등, J. MoI. Biol. 263:730-51 (1996)).
오라시아닌
오라시아닌 A, 오라시아닌 B-1, 및 오라시아닌 B-2로 표시된 세 개의 청색 구리 단백질은 호열성 녹색 글라이딩 광합성 세균인 클로로플렉서스 오란티아쿠스로부터 단리되었다. 두 개의 B 형은 서로 거의 동일한 성질을 갖지만, A형과는 다르다. 도데실황산나트륨-폴리아크릴아미드 겔 전기이동은 14(A), 18(B-2) 및 22(B-1) kDa으로 명백한 단량체 분자량을 보여준다.
오라시아닌 A의 아미노산 서열은 확인되었고 139개의 잔기의 폴리펩타이드라고 밝혀졌다(Van Dreissche 등, Protein Science 8:947-957 (1999)). 만일 His58, Cys123, His128 및 Met132가 알려진 작은 구리 단백질 플라스토시아닌 및 아주린의 경우에서와 같이 점진적인 보존 금속 리간드인 경우에, 상기 His58, Cys123, His128 및 Met132는 예상된 방식으로 간격을 둔다. 또한, 2차 구조 예측은 오라시아닌이 녹농균으로부터 유래된 아주린 및 포플러 잎으로부터 유래된 플라스토시아닌과 유사한 일반적인 β-통형 구조를 가지는 것을 나타낸다. 반면에, 오라시아닌은 작은 구리 단백질 서열 부류들 모두의 서열 특징을 가지는 것으로 나타난다. 아주린의 공통 서열과의 전체적인 동일성은 플라스토시아닌의 공통 서열과 거의 동일하며, 즉 30.5 %의 전체적인 동일성을 가진다. 오라시아닌의 N-말단 서열 영역 1번 내지 18번은 글리신과 히드록시 아미노산이 매우 풍부하다. Id. 클로로플렉서스 오란티아쿠스로(NCBI Protein Data Bank Accession No. AAM12874)부터 유래된 오라시아닌의 쇄 A에 대한 예시적인 아미노산 서열 서열번호:10을 참조하라.
오라시아닌 B 분자는 표준 큐프레독신 접힘을 갖는다. 클로로플렉서스 오란티아쿠스로부터 유래된 오라시아닌 B의 결정 구조가 연구되었다(Bond 등, J. Mol. Biol. 306:47-67 (2001)). 부가적인 N-말단 가닥은 제외로 하고, 분자는 세균의 큐프레독신, 아주린의 분자와 매우 유사하다. 다른 큐프레독신의 경우와 같이, Cu 리간드 중 하나는 폴리펩타이드의 4번째 가닥에 놓이고, 다른 세 개는 7번 가닥 및 8번 가닥 사이의 커다란 루프(loop)를 따라 놓인다. Cu 부위 기하학적 구조는 후자의 세 개의 리간드들 간의 아미노산 간격에 관하여 논의된다. 결정학적으로 특징지어진 오라시아닌 B의 Cu-결합 도메인은 아마도 몇몇의 막-연관 전자-전달 단백질에서 알려진 테더와 현저한 서열 동일성을 보이는 N-말단 말미(tail)에 의해 세포질 막의 주변 세포질 측에 테더 될 것이다. B 형의 아미노산 서열은 McManus 등의 문헌에서 제시된다(J Biol Chem. 267:6531-6540 (1992)). 클로로플렉서스 오란티아쿠스로(NCBI Protein Data Bank Accession No. 1QHQA)부터 유래된 오라시아닌의 쇄 B의 쇄 A에 대한 예시적인 아미노산 서열 서열번호:11을 참조하라.
슈도아주린
슈도아주린은 단일-쇄 폴리펩타이드를 함유하는 청색-구리과이다. 아크로모박터 시클로클라스테스로부터 얻은 슈도아주린의 아미노산 서열은 서열번호:4로 보여진다. 슈도아주린의 X-선 구조 분석은 이러한 단백질 간에 낮은 서열 상동성을 가짐에도 불구하고 아주린에 대하여 유사한 구조를 가지는 것으로 보인다. 두 가지 주요한 차이점은 슈도아주린 및 아주린의 전체적인 구조 사이에 존재한다. 두 개의 α-나선으로 구성되는 아주린에 비하여, 슈도아주린에는 카복시 말단 연장이 있다. 중간-펩타이드 영역에서 아주린은 연장된 루프를 함유하며, 짧은 α-나선을 함유하는 플랩(flap)을 형성하는 슈도아주린을 짧게 했다. 구리 원자에서 매우 중요한 차이점은 MTT 측쇄의 배열 및 아주린보다 슈도아주린에서 현저히 짧은 Met-S 구리 결합 길이이다. 변형된 큐프레독신 유래 펩타이드는 일반적인 기술에 의해 합성될 수 있다. 변이체는 직접적으로 또는 변형 또는 부분적 치환에 의해서 자생 화합물로부터 형성되는 아미노산이다. 변화는 큐프레독신의 약학적 활성이 효력 없게 하는 큐프레독신 유래 펩타이드의 아미노산 서열의 변화를 초래하는 큐프레독신 유래 펩타이드 안에 도입될 수 있다. "비-필수" 아미노산 잔기는 약학적 활의 효력을 잃지 않고 큐프레독신 유래 펩타이드 서열로부터 변화될 수 있는 잔기인 반면에, "필수" 아미노산 잔기는 이러한 약학적 활성을 위해 요구된다.
만들어질 수 있는 "보존" 치환기에 대한 아미노산은 당해 분야에 잘 알려져 있다. 유용한 보존 치환기는 표 1 "선호되는 치환기"에 제시된다. 한 부류의 아미노산인 보존 치환기는 상기 치환기가 큐프레독신 유래 펩타이드의 소정의 약학적 활성을 효력 없게 만들지 않는 한 본 발명의 범위 내에 속하는 동일한 부류의 또 다른 아미노산과 치환된다. 큐프레독신 유래 약학적 활성의 변화를 초래하는 이러한 교환은 이러한 약학적 활성이 상당하는 한 본 발명의 일부로 고려된다. 일부 실시예에서, 큐프레독신 유래 펩타이드의 약학적 활성은 야생형 큐프레독신으로부터 유래되는 특이적 활성보다 약 5 % 적고, 약 10 % 적고, 약 25 % 적고, 약 50 % 적다. 큐프레독신 유래 펩타이드의 다른 개선된 특성, 예를 들어 길어진 혈장 반감기 또는 감소된 면역원성에 의해 상쇄된다면 큐프레독신 유래 펩타이드의 특이적 활성의 약간의 손실은 용인될 수 있을 것으로 인정될 것이다.
선호되는 치환기
기존 치환기 예시적인 치환기 선호되는 치환기
Ala(A) Val, Leu, Ile Val
Arg(R) Lys, Gln, Asn Lys
Asn(N) Gln, His, Lys, Arg Gln
Asp(D) Glu Glu
Cys(C) Ser Ser
Gln(Q) Asn Asn
Glu(E) Asp Asp
Gly(G) Pro, Ala Ala
His(H) Asn, Gln, Lys, Arg Arg
Ile(I) Leu, Val, Met, Ala, Phe, Norleucine Leu
Leu(L) 노르루신, Ile, Val, Met, Ala, Phe Ile
Lys(K) Arg, Gln, Asn Arg
Mey(M) Leu, Phe, Ile Leu
Phe(F) Leu, Val, Ile, Ala, Tyr Leu
Pro(P) Ala Ala
Ser(S) Thr Thr
Thr(T) Ser Ser
Trp(W) Tyr, Phe Tyr
Tyr(Y) Trp, Phe, Thr, Ser Phe
Val(V) Ile, Leu, Met, Phe, Ala, 노르루신 Leu
(1) β-시트 또는 α-나선 배열과 같은 폴리펩타이드 골경의 구조, (2) 전하, (3) 소수성, 또는 (4) 측쇄의 큰 규모에 영향을 미치는 "비-보존적" 치환기는 큐프레독신 유래 펩타이드의 약학적 활성을 변형할 수 있다. 표 2에서 나타내듯이, 잔기는 공통의 측쇄 성질에 기초하여 군으로 나뉘어진다. 비-보존적 치환기는 이러한 부류 중 하나의 구성원을 또 다른 부류로 교환하는 것을 수반한다.
한 부류의 아미노산인 비-보존적 치환기는 상기 치환기가 큐프레독신 유래 펩타이드의 소정의 약학적 활성을 효력 없게 만들지 않는 한 본 발명의 범위 내에 속하는 동일한 부류의 또 다른 아미노산과 치환된다. 큐프레독신 유래 약학적 활성의 변화를 초래하는 이러한 교환은 이러한 약학적 활성이 상당하는 한 본 발명의 일부로 고려된다.
아미노산 부류
부류 아미노산
소수성 노르루신, Met, Ala, Val, Leu, Ile
중성 친수성 Cys, Ser, Thr
산성 Asp, Glu
염기성 Asn, Gln, His, Lys, Arg
쇄 형태 교란성 Gly, Pro
방향족성 Trp, Tyr, Phe
큐프레독신 유래 펩타이드에 대한 변형은 올리고뉴클레오티드-매개(부위 특이적) 돌연변이, 알라닌 스캐닝 및 PCR 돌연변이와 같은 당해 분야에 알려진 방법을 사용하여 이루어질 수 있다. 부위 특이적 돌연변이(), 카세트 돌연변이(cassette mutagenesis), 재한 선택 돌연변이() 또는 다른 알려진 기술은 변종 핵산을 암호화하는 큐프레독신 유래 펩타이드를 생산하기 위해 복제된 DNA상에서 수행될 수 있다. 게다가, 큐프레독신의 구조적 등가물인 큐프레독신 유래 펩타이드를 암호화하는 뉴클레오티드는 당해 분야에서 잘 알려진 방법에 의해 합성될 수 있다. 나아가, 변형된 큐프레독신 유래 펩타이드인 단백질 분자는 당해 분야에서 잘 알려진 방법에 의해 합성될 수 있다.
큐프레독신 진입 도메인을 위한 핵산의 암호화 및 카르고 화합물에 연결된 큐프레독신 진입 도메인의 복합체
다른 양태에서, 본 발명은 본 발명의 변형된 큐프레독신 유래 펩타이드를 암호화하는 핵산 분자를 제공한다. 이런 핵산 분자는 당해 분야의 알려진 기술의 조합에 의해 제조될 수 있다. 예를 들어, 변형된 큐프레독신 유래 펩타이드에 대한 핵산 서열은 화학적 합성 또는 복제에 의해 개별적으로 제조될 수 있다.
큐프레독신 , 변형된 큐프레독신 또는 변형된 큐프레독신 -유래 펩타이드와 나노입자를 포함하는 혼성 시스템
또 다른 양태에서, 본 발명은 녹농균 아주린(서열번호:1)과 같은 큐프레독신 및/또는 본 명세서에 개시된 하나 이상의 방법 또는 기술을 사용하여 변형될 수 있는 큐프레독신 유래 펩타이드인 생물학적 분자를 제공하며, 이러한 생물학적 분자는 금 또는 백금과 같은 귀금속일 수 있는 나노입자와 콘주게이션된다. 생물학적 분자는 전기적 상호작용 또는 다른 방식을 통해 나노입자에 콘주게이션 될 수 있다. 특히, 콘주게이션은 전자 전달을 통해 이루어질 수 있다. 문헌[Delfino, I 및 Cannistraro, S., "Optical investigation of the electron transfer protein azurin-gold nanoparticle system," Biophysical Chemistry 139 (2009) 1-7 (available online 30 Sept. 2008)]을 참조하며, 상기 공개문헌은 본 명세서에 전체가 참조로 포함된다. 일부 실시예에서, 변형된 큐프레독신 유래 펩타이드 및 나노입자를 포함하는 혼성 시스템은 이미징, 진단 및/또는 암 치료의 목적을 위해 사용될 수 있다.
변형된 큐프레독신 유래 펩타이드를 함유하는 약학 조성물
변형된 큐프레독신 유래 펩타이드를 함유하는 약학 조성물은 임의의 종래 수단, 예를 들어 종래의 혼합, 용해, 과립화, 캡슐화, 포집화 또는 동결건조 공정에 의해 제조될 수 있다. 변형된 큐프레독신 유래 펩타이드는 당해 분애에서 알려진 약학적으로 허용가능한 담체와 손쉽게 혼합될 수 있다. 이러한 담체는 정제, 환약, 당제(dragee), 캡슐, 액형, 겔, 시럽, 슬러리(slurry), 현탁액 등으로 제형화되도록 제조될 수 있다. 또한, 예를 들어, 적합한 부형제는 필러 및 셀룰로오스 제제를 포함할 수 있다. 다른 부형제는 예를 들어, 방향제, 착색제, 탈점착제(detackifiers), 증점제, 및 다른 허용가능한 첨가제, 보조제 또는 바인더(binders)를 포함할 수 있다. 이러한 조성물은 예를 들어, 암의 치료 또는 진단, 부적합한 혈관생성의 치료, HVV 및/또는 말라리아에 의한 감염, 및 에프린-신호전달에 관련된 질환의 치료에 사용될 수 있다. 상기 조성물은 환자가 앓고 있는 질환을 예방하거나 치료하기에 충분한 양으로 투여될 수 있다. 일반적으로, 상기 환자 생물체는 인간 또는 동물과 같은 포유류이다.
큐프레독신 진입 도메인을 함유하는 조성물의 투여
변형된 큐프레독신 유래 펩타이드를 함유하는 조성물은 임의의 적절한 경로, 예를 들어 경구, 구강, 흡입, 설하(sublingual), 직장, 질, 경요도, 비강, 국부, 경피를 통해, 즉 경피적으로 또는 비경구적으로(정맥 내 투여, 근육 내 투여, 피하 투여 및 관동맥내 투여를 포함함) 투여될 수 있다. 조성물 및 이의 약학 조성물은 이들의 의도된 목적을 달성하기 위해 효과적인 양으로 투여될 수 있다. 질환을 앓는 환자를 치료하기 위해 투여되는 경우에, 상기 조성물은 치료적 유효량으로 투여된다. "치료적 유효량"은 치료를 받는 환자의 발달을 막기 위해 효과적인 양이거나, 치료를 받는 환자의 기존의 증상을 완화하기 위해 효과적인 양이다. 치료적 유효량의 결정은 당해 분야의 통상의 기술자의 능력 내에 있다.
다양한 실시예에서, 상기 조성물은 담체 및 부형제(완충액, 탄수화물, 만니톨, 단백질, 폴리펩타이드 또는 아미노산, 예를 들어 글리신, 항산화제, 세균 발육 저지제, 킬레이트제, 서스펜션화제, 증점제 및/또는 방부제를 포함하지만, 이에제한되지 않음), 물, 오일, 식염수, 수성 덱스트로오스 및 글리세롤 용액, 대략의 약학적 조건에 요구되는 다른 약학적으로 허용가능한 보조 물질, 예를 들어 완충제, 등장화제(tonicity adjusting agent), 습윤제 등을 포함한다. 당해 분야의 통상의 기술자에게 알려진 임의의 적합한 개리어는 본 발명의 조성물을 투여하기 위해 이용될 수 있는 반면에, 담체의 유형은 투여의 방식에 따라 각기 달라질 것이라고 인식될 것이다. 또한, 화합물은 잘 알려진 기술을 사용하여 리포솜 내에 캡슐화될 수 있다. 또한, 생분해성의 마이크로스피어(microsphere)는 본 발명의 조성물에 대한 담체로서 이용될 수 있다. 적합한 생분해성의 마이크로스피어는 예를 들어, 미국특허 제4,897,268호, 제5,075,109호, 제5,928,647호, 제5,811,128호, 제5,820,883호, 제5,853,763호, 제5,814,344호 및 제5,942,252호에서 보여진다.
본 명세서에서 사용되는 "화합물"은 본 발명의 펩타이드, 아미노산 서열, 카르고 화합물 및 복합체를 포함한다.
본 발명의 조성물은 종래의 잘 알려진 살균 기술에 의해 살균될 수 있거나, 살균 여과될 수 있다. 결과로 초래된 수성 용액은 사용을 위해 포장되거나 동결 건조되며, 동결 건조된 제제는 투여하기 전에 살균 용액과 혼합된다.
본 발명의 조성물은 다양한 방식으로 투여될 수 있으며, 상기 방식은 주사(예, 피내, 피하, 근육 내, 복강 내 등), 흡입, 국부 투여, 좌약, 경피 패치 사용 또는 입에 의한 방식을 포함한다. 투여가 주사에 의한 경우에, 조성물은 수성 용액으로 제형화 될 수 있으며, 바람직하게는 행크 용액(Hanks solution), 링거 용액 또는 생리학적 식염 완충제와 같은 생리학적으로 양립될 수 있는 완충제에서 제형화 될 수 있다. 용액은 서스펜션화제, 안정화제 및/또는 분산제와 같은 제형화제 (formulatory agents)를 함유할 수 있다. 대안적으로, 상기 조성물은 사용하기 전에 적합한 담체, 예를 들어 멸균 주사용 증류수(sterile pyrogen-free water)를 갖는 구조를 위해 파우더형일 수 있다. 투여가 흡입에 의하는 경우, 상기 조성물은 가압된 팩으로부터 연무질 분무(aerosol spray)의 형태 또는 적합한 분사제, 예를 들어 디클로로디플루오로메탄, 트리클로로플루오로메탄, 이산화탄소 또는 다른 적합한 기체의 사용과 함께 분무기로 전달될 수 있다. 가압된 연무질의 경우에, 투여량 단위는 계량된 양을 전달하기 위한 밸브를 제공함으로써 결정할 수 있다. 예를 들어, 흡입기 또는 취분기에서 사용하기 위한 젤라틴의 캡슐 및 카트리지는 단백질의 파우더 믹스 및 락토오스와 녹말과 같은 적합한 파우더 기제(base)를 함유하여 제형화될 수 있다.
투여가 국부 투여에 의하는 경우에, 상기 조성물은 당해 분야에서 잘 알려진 용액, 겔, 연고, 크림, 현탁액 등으로 제형화될 수 있다. 일부 실시예에서, 투여는 경피 패치의 방식에 의한다. 투여가 좌약에 의하는 경우에(예, 직장 또는 질), 조성물은 종래의 좌제 기제(suppository base)를 함유하는 조성물로 제형화될 수도 있다.
투여가 경구적인 경우에, 상기 조성물은 당해 분야에 잘 알려진 약학적으로 허용가능한 담체와 함께 손쉽게 제형화될 수 있다. 만니톨, 락토오스, 마그네슘 스테아레이트 등과 같은 고형 담체는 이용될 수 있으며; 이러한 담체는 치료되는 환자가 경구적 섭취를 하기 위해 케모탁신을 정제, 환약, 당제, 캡슐, 용액, 겔, 시럽, 슬러리, 현탁액 등으로 제형화할 수 있게 한다. 예를 들어, 파우더, 캡슐 및 정제와 같은 경구 고형 제형을 얻기 위해, 적합한 부형제는 당, 셀룰로오스 제제, 과립제 및 결합제와 같은 필러를 포함한다.
또한, 당해 분야에 잘 알려진 다른 편리한 담체는 세균성 캡슐형 다당류(bacterial capsular polysaccharide), 덱스트란 또는 유전자변형벡터와 같은 다가의 담체를 포함한다. 게다가, 상기 조성물을 포함하는 서방형 제형은 오랜 기간동안 조성물의 방출을 가능하게 하여, 서방형 제형이 아닌 경우에, 치료적 효과를 야기거나 향상시키기 전에 조성물이 피험자의 시스템으로부터 제거되고/제거되거나 예를 들어, 단백질 분해 효소 및 간단한 가수 분해에 의해 분해될 것이다.
정확한 제형, 투여경로 및 투여량은 환자의 질환을 고려하여 담당의사에 의해 일반적으로 결정된다. 투여량 및 투여 간격은 치료적 효과를 유지하기에 충분한 복합체의 혈장 수준을 제공하기 위해 개별적으로 조절될 수 있다. 일반적으로, 소정의 조성물은 투여의 의도된 경로 및 표준 의약에 대하여 선택된 약학적 담체와 혼합되어 투여된다.
적절한 투여량은 예를 들어, 이용되는 큐프레독신 진입 도메인을 함유하는 화합물, 수용자(the host), 투여의 방식 및 치료되거나 진단되는 질환의 종류와 극심함에 따라서 각기 다를 것이다. 반면에, 본 발명의 방법 중 일 실시예에서, 인간에서 충분한 치료 결과는 체중에 대하여 변형된 큐프레독신 유래 펩타이드를 함유하는 화합물을 약 0.001 내지 약 20 mg/kg의 투여량으로 매일 얻는 것으로 보여진다. 일 실시예에서, 인간의 치료를 위해 표시된 일일 투여량은 예를 들어, 일일 투여량, 주간 투여량, 월간 투여량 및/또는 지속적 투여량으로 편리하게 투여되는 변형된 큐프레독신 유래 펩타이드를 함유하는 화합물의 약 0.7 mg 내지 약 1400 mg의 범위일 수 있다. 일일 투여량은 하루에 1 내지 12번으로 나누어진 별개의 투여량일 수 있다. 대안적으로, 투여랑은 격일마다, 3일마다, 4일마다, 5일마다, 6일마다, 매주, 및 유사하게 1일부터 31일까지 증가시키며 투여될 수 있다. 투여량은 정제, 패치, 즉 투여 등을 포함하는 임의의 적용되는 투약 형태를 사용하여 지속적, 간헐적 또는 단일 투여량일 수 있다. 더 구체적으로, 상기 조성물은 치료적 유효량으로 투여된다. 구체적 실시예에서, 상기 치료적 유효량은 체중에 대해 약 0.01 내지 20 mg/kg이다. 구체적 실시예에서, 투여량 수준은 약 10 mg/kg/day, 약 15 mg/kg/day, 약 20 mg/kg/day, 약 25 mg/kg/day, 약 30 mg/kg/day, 약 35 mg/kg/day, 약 40 mg/kg/day, 약 45 mg/kg/day 또는 약 50 mg/kg/day이다.
변형된 큐프레독신 유래 펩타이드를 함유하는 화합물을 환자에게 도입하는 방법은, 일부 실시예에서, 질환을 치료하기 위해 알려진 다른 약물과 함께 공동 투여된다. 이러한 방법은 당해 분야에 잘 알려져 있다. 구체적 실시예에서, 변형된 큐프레독신 유래 펩타이드를 함유하는 화합물은 암, HIV, 말라리아, 부적절한 혈관 형성 및 에프린 신호와 관련된 질환을 치료하기 위한 다른 약물과 함께 또는 이를 함유하는 공동 투여량 또는 혼합제의 일부분이다. 많은 다른 이러한 화합물은 당해 분야의 통상의 기술자에게 알려져 있고, 명시적으로 참조로 포함되는 특허 출원서에 의해 제공된다.
큐프레독신 유래 펩타이드를 암호화하는 핵산 분자 또는 큐프레독신 유래 펩타이드와 카르고 화합물을 결합시키는 융합 단백질은 벡터 안으로 삽입될 수 있고, 유전자 피료 벡터로 사용된다. 유전자 치료 벡터는 예를 들어, 정맥 내 주사, 국부 투여(Nabel 등, 미국특허 제5,328,470호), 또는 정위 주사(stereotactic injection)(Chen 등, Proc Natl Acad Sci USA 91 :3054-3057 (1994))에 의해 피험자에게 전달될 수 있다. 유전자 치료 벡터의 약학 제제는 허용가능한 희석제를 포함할 수 있거나 유전자 전달 담체가 박혀있는 지효성 기질을 포함할 수 있다.
대안적으로, 완전한 유전자 전달 벡터는 재조합 세포, 예를 들어 레트로바이러스 벡터로부터 그대로 제공될 수 있는 곳에서, 약학 제제는 유전자 전달 시스템을 만들어 내는 하나 이상의 세포를 포함할 수 있다.
일 양태에서, 상기 조성물은 복합체가 당소에서 생성되도록 DNA로서 전달된다. 일 실시예에서, DNA는 예를 들어, 문헌[Ulmer 등, Science 259:1745-1749(1993)]에서 설명되고, 문헌[Cohen, Science 259:1691-1692 (1993)]에서 검토된 것처럼 "네이키드(naked)"형이다. 네이키드 DNA의 흡수는 담체, 예를 들어 생분해성 비드 위로 DNA를 코팅함으로써 증가될 수 있으며, 이는 세포 안으로 효과적으로 운반된다. 이러한 방법에서, DNA는 당해 분야의 통상의 기술자에게 알려진 다양한 전달 시스템 중 임의의 시스템 내에 존재할 수 있으며, 상기 시스템은 핵산 발현 시스템, 세균 및 바이러스 발현 시스템을 포함한다.
이러한 발현 시스템 안에 DNA를 포함시키기 위한 기술은 당해 분야의 통상의 기술자에게 잘 알려져 있다(예를 들어, WO90/11092, WO93/24640, WO 93/17706, 및 미국특허 제5,736,524호 참조).
유기체에서 유기체로 유전 물질을 실어 나르기 위해 사용되는 벡터는 두 개의 일반적인 부류로 나뉘어질 수 있다: 복제 벡터는 적절한 숙주세포에서 증식하기 위해 필수적이지 않은 영역을 갖는 플라스미드 또는 파지(phage)를 복제하고, 외래 DNA 안으로 삽입될 수 있으며; 상기 외래 DNA는 마치 벡터의 구성성분인 것처럼 복제되고 증식된다. 발현 벡터(예를 들어, 플라스미드, 효모, 또는 동물 바이러스 게놈)는 조성물의 DNA와 같은 외래 DNA를 전사하고 번역하기 위해 숙주세포 또는 조직 안으로 외래 유전 물질을 도입하기 위해 사용된다. 발현 벡터에서, 도입된 DNA는 삽입된 DNA를 전사하기 위해 숙주세포에 신호를 보내는 프로모터와 같은 요소에 작동하도록 연결된다. 특정 인자에 반응하여 유전자 전사를 통제하는 유도성 프로모터와 같은 일부 프로모터는 특히 유용하다. 유도성 프로모터에 작동하도록 연결되는 조성물 폴리뉴클레오티드는 본 발명의 변형된 큐프레독신 유래 펩타이드의 발현을 통제할 수 있다. 전형적인 유도성 프로모터의 예는 α-인터페론, 열충격, 중금속 이온, 및 글로코코르티코이드(Kaufman, Methods Enzymol. 185:487-511 (1990))와 테트라시클리과 같은 스테로이드에 즉각 반응하는 것들을 포함한다. 다른 소정의 유도성 프로모터는 구성체가 도입되는 세포에 내생하지 않지만, 반면에 유도 물질이 외인성으로 공급되는 경우에 이러한 세포에서 즉각 반응하는 것을 포함한다. 일반적으로, 유용한 발현 벡터는 종종 플라스미드이다. 반면에, 바이러스 매개체(예, 복제 결함 레트로바이러스, 아데노바이러스 및 아데노 연관 바이러스)와 같은 발현 벡터의 다른 형태가 고려된다. 벡터 선택은 사용되는 유기체 또는 세포 및 벡터의 소정의 거동(fate)에 의해 좌우된다. 일반적으로, 벡터는 신호 서열, 복제 지점, 표지 유전자, 인핸서(enhancer) 요소, 프로모터 및 전사 종결 서열을 포함한다.
변형된 큐프레독신 유래 펩타이드를 포함하는 키트
또 다른 양태에서, 본 발명은 상자 또는 컨테이너에 다음 중 하나 이상을 함유하는 키트를 제공한다: (1) 변형된 큐프레독신 유래 펩타이드를 포함하는 시약; (2) 약학적으로 허용가능한 보조제 또는 부형제를 함유하는 시약; (3) 시린지와 같은, 투여를 위한 담체; 및 (4) 투여를 위한 설명서. (1) 내지 (4) 구성성분 중 두개 이상이 동일한 컨테이너에서 발견되는 예도 고려된다.
키트가 공급되는 경우에, 조성물의 다른 구성성분은 분리된 컨테이너에 포장되고 사용 직전에 혼합된다. 구성성분의 이러한 포장은 활성 성분의 기능을 잃지 않고 오랜 기간 동안 별도로 저장을 가능하게 할 수 있다. 키트에 포함된 시약은 상이한 구성성분의 수명이 보존되고 컨테이너의 물질에 의해 흡수되거나 변화되지 않도록 임의의 종류의 컨테이너에 공급될 수 있다. 예를 들어, 밀봉된 유리 앰플은 동결 건조된 폴리펩타이드 또는 폴리뉴클레오티드, 또는 질소와 같은 중성 비활성 기체 하에서 포장되었던 완충액을 함유할 수 있다. 앰플은 유리, 폴리카보네이트, 폴리스티렌 등과 같은 유기 폴리머, 세라믹, 금속 또는 유사한 시약을 보유하기 위해 일반적으로 이용되는 임의의 다른 물질과 같은 임의의 적합한 물질로 구성될 수 있다. 적합한 컨테이너의 다른 예는 앰플과 유사한 물질, 및 알루미늄 또는 합금과 같은 호일이 깔린 내부를 포함할 수 있는 봉투(envelopes)로 만들어질 수 있는 단순한 병을 포함한다. 다른 컨테이너는 시험관, 유리병, 플라스크, 병, 주사기 등을 포함한다. 컨테이너는 피하 주사 바늘에 의해 뚫릴 수 있는 스토퍼(stopper)를 갖는 병과 같은 멸균 접근 포트를 가질 수 있다. 다른 컨테이너는 제거시에 구성성분이 혼합될 수 있도록 하는 손쉽게 제거가능한 막에 의해 분리되는 두 개의 칸을 가질 수 있다. 제거가능한 막은 유리, 플라스틱, 고무 등일 수 있다.
또한, 키트는 교육용 자료와 함께 공급될 수 있다. 설명서는 종이 또는 다른 기판상에 인쇄될 수 있고/있거나 플로피 디스크, CD-ROM, DVD-ROM, Zip 디스크, 비디오테이프, 오디오테이프, 플래시 메모리 장치 등과 같은 전자 장비로 읽을 수 있는 매체로서 제공될 수 있다. 구체적인 설명서는 키트와 물리적으로 관련되지 않을 수 있으며; 대신에, 사용자는 키트의 제조자 또는 배급자에 의해 명시되는 인터넷 웹 사이트로 보내질 수 있거나, 또는 전자 메일로 공급된다.
본 발명의 더 완벽한 이해는 이어지는 구체적인 실시예를 참조하여 얻어질 수 있다. 실시예는 예시의 목적으로만 설명되고, 본 발명의 범위를 제한하기 위한 의도가 아니다. 형태의 변화 및 등가물의 치환은 방편을 제안하거나 제시할 수 있는 상황으로 고려된다. 구체적인 용어가 본 명세서에서 이용됐음에도 불구하고, 이러한 용어는 기술적인 의미로 생각되고 제한하기 위한 목적은 아니다. 상기 기술된 본 발명의 변형 및 변이는 본 발명의 사상 및 범위로부터 벗어나지 않고 이루어질 수 있고, 그러므로 첨부된 실시예에 의해 보여지듯이 이러한 제한만 받아들여져야 할 것이다.
실시예
암을 앓는 환자를 변형된 큐프레독신 유래 펩타이드로 치료
티오에테르 고리화된 p28(서열번호:13) 융합(연구 약물)의 상 I/II 임상 실험은 암을 앓는 환자에게서 수행될 것이다. 구체적으로, 녹농균으로부터 유래된 p28(서열번호:13)은 티오에테르 고리화에 의해 변형될 것이다.
임상경과 및 방사선 사진의 경과 또는 현재 사용가능한 FDA-승인된 화학요법용 약물에 의해 충분한 치료를 한 후에 재발을 보여주는 조직학적으로 확인된 유방암, 대장암 및 흑색종암을 앓는 49명의 성인 환자는 연구 약물을 투여하는 개방표지(open label) 전향적 연구에 등록될 것이다. 연구에 등록되기에 적합하기 위해서, 모든 환자는 승인된 코스의 화학요법 처방을 종료한 후에 측정가능한 증가된 종양의 부피를 보여준다. 끊임없는 전이의 축적 및/또는 크기나 부피의 지속적인 증가의 근거는 조직학적으로 규명되어야만 한다. 이런 조직학적인 증명은 미세바늘 흡임(FNA) 생체 조직 검사에 의해 얻을 수 있다.
치료 프로그램은 시카고, 일리노이대학의 기관감사위원회 및 FDA에 따른 모든 환자로부터 고지에 입각한 동의를 얻은 후에 시작했다. 환자는 제안된 치료의 효과에 대한 적절한 평가를 방해할 수 있는 다른 악성종양, 이전의 악성종양 병력, 혈액질환, 인슐린 의존성 당뇨병 또는 다른 심각한 심혈관계 질병과 같은 병발성의 질환을 갖지 않는다. 간 기능 연구(LFT)를 포함하는 기준선 혈액 검사(완전 혈구 측정[CBC] 및 혈청 화학)는 치료의 개시 이전에 수행될 것이다. 모든 적합한 환자는 임상시험기간 동안에 임의의 암 화학치료를 동시에 받으면 안된다.
연구 약물은 12주 동안 약학적으로 허용가능한 제제의 연구 약물을 매일 정맥 내로 주사함으로써 투여될 것이고, 피험자는 독성을 제한하는 임의의 투여량에 대해서 관찰될 것이다. 투여량 수준은 10 mg/kg/day로 시작하여 5 mg/kg/day씩 증가시켜서 최대 50 mg/kg/day의 투여량까지 7 종류의 투여량 수준이 있다. 각각의 투여량 수준의 효능은 후기의 측정가능한 암(유방, 결장 및 흑색종)을 앓는 7명의 환자에게서 기록될 것이다.
반응은 측정가능한 종양을 2차원(a 및 b)으로 측정함으로써 추정할 것이다. 1) 목표 전이성 종양의 총 소멸은 완전 반응(complete response, CR)으로서 고려될 것이며; 2) 75 % 감소는 훌륭한 부분적 반응(partial response, PR)으로 고려될 것이고; 3) 좋은 반응(good response, PR)은 치료 후에 50 %로 크기가 감소될 것이다. 4) 크기의 25 % 감소는 안정한 질병(stable disease, SD)으로 고려될 것이고, 5) 크기의 25 % 미만의 감소는 반응이 없는 것(no response, NR)으로 고려될 것이다. 질병의 경과를 보여주는 환자는 그들의 치료가 중단될 것이지만, 추가로 12주 동안 이어질 것이다.
총 소멸 및 목표 전이성 종양의 크기의 임의의 감소는 아주린 치료가 암을 치료하는데에 효과적이라는 것을 보여준다. 티오에테르 고리화된 p28(서열번호:13) 치료가 효과적이라는 다른 암시는 새로운 전이성 종양의 출현에 대한 감소된 비율 및 종양과 관련된 혈관생성의 감소이다. 본 발명에서 설명되는 실시예 및 시스템의 다양한 변형 및 변이는 본 발명의 범위 및 사상으로부터 벗어나지 않고 당해 분야의 기술자에게 자명하다. 본 발명이 구체적인 실시예와 함께 설명되지만, 청구되는 발명은 이러한 구체적 실시예로 지나치게 제한되지 않는 것으로 이해되어야 한다. 분명히, 관련 분야의 기술자에게 자명한 본 발명을 수행하기 위해 설명된 방식의 다양한 변형은, 이어지는 실시예의 범위 내에 있다고 생각된다.
실시예 18 - 인간 세포주 안으로 p18 (서열번호:14) 및 p28 (서열번호:13)의 진입
세포 배양 및 세포주 : 인간 암 및 비-암(불멸 및 비-불멸) 세포주를 ATCC[폐암(A549 및 NCI-H23 선암), 정상 폐(CCD-13Lu), 전립선암(DU145 및 LN-CAP), 정상 전립선(CRL11611), 유방암(MCF-7), 정상 유방(MCF-10A), 대장암(HCT116), 정상 결장(CCD33Co), 섬유육종(HT1080), 및 난소암(SK-OV3 선암)]로부터 얻었다. 피부로부터 단리된 정상 섬유아세포를 규명했다. Dr. S. W. Tsao(홍콩대학교)에 의해 정상 난소 세포(HOSE6-3)을 기증받았다. 흑색종 주(UISO-Mel-2,23,29)를 규명했고 특정했다. UISO-Mel-2이외의 모든 세포를 10 % 열-비활성 소태아혈청(Atlanta Biological Inc., Lawernceville, GA), 100 units/mld의 페니실린 및 100 μg/ml의 스트렙토마이신이 보충된 MEM-E(Invitrogen, Carlsbad, CA)에서 37 ℃, 5 %의 CO2 또는 공기 조건에서 배양했다.
증식도 측정/세포 성장 : 흑색종 세포를 12 x 103 세포/웰의 밀도로 평편한 바닥의 24 웰 플레이트(Becton Dickinson, Franklin Lakes, NJ)에 심었다(네 개의 모사체). 24시간 후에 배지를 교환했고, 신선한 p18, p28(서열번호:13), 아주린 또는 펩타이드(여덟 개의 모사체)가 없는 유사한 부피의 배지를 72시간 동안 매일 첨가했다. 그 다음에, 세포를 Beckman Coulter(Z 1 Coulter particle counter)로 세었다. 값들은 네 개의 모사체의 평균±SD를 보여준다.
MTT 측정 : 흑색종 세포를 2000 세포/웰의 밀도로 평편한 바닥의 96 웰 플레이트(Becton Dickinson, Franklin Lakes, NJ)에 심었고, 24시간 동안 부착되도록 방치하였다. 그 다음에,신선하게 제조된 펩타이드(10 μl) 또는 배양 배지를 각각의 웰에 첨가했다. 24시간 후에, 배지를 교환했고, p18(서열번호:14), p28(서열번호:13) 또는 아주린을 매일 첨가했다. 72시간 동안 배양 후에, 10 μl의 MTT 시약(Trevigen, Gaithersburg, MD)을 각각의 웰에 첨가했으며, 표본을 3시간 동안 배양했으며, RT/sig 100 μl의 세제를 각각의 웰에 첨가했고, 상기 표본을 37 ℃에서 추가적인 3시간 동안 배양했다. SpectraMax 340 플레이트 리더(Molecular Devices Corporation, Sunnyvale, CA)를 이용하여 흡광도를 측정했고, 흡광도 570 nm에서 비처리된 대조군에 관하여 처리된 세포의 퍼센트 변화를 확인했다. 값들은 평균±SD를 보여준다. 대조군과 처리된 군 간의 상당성은 Student's t-test에 의해 확인했다.
펩타이드 합성 : C S Bio, Inc.(Melo, Park, CA)는 p18, Leu50-Gly67 LSTAADMQGVVTDGMASG(서열번호:14), p28 Leu50-Asp77 LSTAADMQGVVTDGMASGLDKDYLKPDD(서열번호:13), p18b Val60-Asp77 VTDGMASGLDKDYLKPDD(서열번호:3526), MAP, 마스토파란-7, 및 폴리아르기닌(Arg-8, RRRRRRRR, 서열번호:3527)을 합성했다. 동결건조된 파우더 부분 표본으로 펩타이드를 받았고, 밀폐된 데시케이터(desiccators)에서 -20 ℃로 저장했다. 차후에 질량 분석기 및 95 %를 초과하는 순도와 물질균형을 갖는 역상 HPLC로 모든 펩타이드를 분석했다.
아주린 펩타이드에 대한 예측 모델링 : 아주린 유해 펩타이드에 대한 롭슨(Robson) 구조 모델을 생성하기 위해 GENETYX 소프트웨어(ver. 6.1)를 사용했다(Gamier, J., Osguthorpe, D. J., 및 Robson, B., J Mol Biol, 120: 97-120 (1978)). 강한 막 접촉을 위한 주어진 단백질 구조를 예측하고 이러한 접촉을 가장 형성할 거 같은 단백질 표면의 영역을 정의하기 위해 MAPAS 소프트웨어를 사용했다(Sharikov, Y. 등, Nat Methods, 5: 119 (2008)). 만일, 단백질, 즉 아주린이 3 보다 큰 막 친화성 잔기 점수(MRS), 60 % 보다 큰 막 친화성 면적 점수(MAS), 2.5 보다 큰 막 친화성 비대칭도 계수(Kmpha)를 가진다면, 단백질이 진정한 막-접촉 영역을 가질 높은 개연성을 갖는다.
펩타이드 /단백질 표지 : 1 ml PBS와 Alexafluor 568 염료(Molecular Probes, Eugene, OR)를 1:2의 비율로 혼합된 것에 펩타이드를 용해시켰고, 100 μl의 이탄산나트륨을 첨가했고, 지속적으로 교반하며 4 ℃에서 상기 혼합물을 밤새도록 배양했다. p12(서열번호:3506)에 대하여 Slide-A-Lyzerg Dialysis Cassettes 1000 MWCO를 사용하고 이외의 것에 대하여 2000 MWCO를(Pierce Biotechnology, Rockford, IL) 사용하여 차가운-PBS에 대하여 투석함으로써 자유 염료(free dye)로부터 표지된 펩타이드를 분리했다.
세포 침투 공초점 분석 : 세포를 유리 커버글라스상에 심었고, 부착되도록 37 ℃, 5 % CO2 하에서 밤새도록 방치하였다. 세포를 신선한 배지로 씻어냈고, Alexafluor 568 표지된 아주린 펩타이드(20 μM) 또는 Arg-8(서열번호:3527)(5 μM)을 함유하는 미리 데워진 배지에서 37 ℃로 2시간 동안 배양하거나, 배지에서만 배양했다. 배양 후에, 커버글라스를 PBS로 3회 씻어냈고, 세포를 2.5 % 포르말린에서 5분간 고정했고, PBS로 2회, 증류수로 1회 세척했고, 커버글라스는 핵 카운터 염색(nuclear counter staining)(VECTASHIELD® Vector Laboratories, Burlingame CA)을 위해 1.5 μg/ml를 함유하는 배지에 놓았다. 세포의 흡수 및 분포를 역 공초점 레이저 현미경 하에서 사진을 찍었다(Model LC510, Carl Zeiss Inc., Gottingen, Germany).
2시간 동안 37 ℃에서 Alexafluor 568 표지된 아주린 또는 펩타이드를 갖는 유리 커버글라스 상에서 자라나는 배양 세포는 리소좀 또는 미토콘드리아와 함께 국부화된 펩타이드를 확인했다. 미트로트랙커(MitroTracker® Green FM Invitrogen Corporation, Carlsbad, CA) 또는 리소트랙커(LysoTracker® Green DND-26 Invitrogen Corporation, Carlsbad, CA)를 배양 중 마지막 30분 동안 첨가했다(최종 농도 1 μM). 세포를 PBS로 3회 씽서냈고, 세포를 2.5 % 포르말린에서 5분간 고정했고, PBS로 2회 세척했고, 15분 동안 PBS 중의 0.1 % Triton-X100에서 배양했다. 그 다음에, 1 % BSA를 갖는 PBS에서 1 μg/ml의 집토끼 항-인간 골긴(rabbit anti-human golgin) 또는 항 인간 카베올린 I(Abcam, Cambridge, MA)와 함께 세포를 배양했다. 4 ℃에서 1시간 배양 후에, 커버글라스를 PBS로 한번 세척했고, Alexafluor 468이 컨쥬게이션된 염소 항-집토끼 항체를 함유하는 PBS에서 10분간 배양했고, PBS로 2회 그리고 증류수로 1회 세척했다. 그 다음에, 커버글라스를 핵 카운터 염색을 위해 1.5 μg/ml를 함유하는 배지에 놓았다. Alexafluor 568(적색) 및 Alexafluor 468(녹색)의 공동 국부화(황색)를 분석했고, 사진찍었다.
커버글라스 상의 UISO-Mel-2 세포를 100 μg/ml의 헤파린 황산염(Sigma-Aldrich, St. Louis, MO)를 함유하는 MEM-E에서 30분 동안 선배양했고, p18(서열번호:14), p28(서열번호:13) 또는 Arg-8(서열번호:3527)를 최종 농도가 20 μM이 되도록 첨가했다. 1시간 후에, 커버글라스를 상술된 바와 같이 세척했고, 고정했고, 분석했다.
FFACS 에 의한 세포 침투 : 세포(1.0 x 106/500 μl PBS)를 Alexafluor 568 표지된 pl8(서열번호:14) 또는 p28(서열번호:13)(20 μM), Arg-8(서열번호:3527)(5 μM)과 함께 37 ℃에서 2시간 동안 배양하거나 배지만 있는 조건에서 배양했고, PBS로 3회 세척했고, 2.5 % 포르말린에서 5분간 고정했고, PBS로 2회 세척했고, 200 μl PBS에서 재현탁시켰고, 단일 세포 현탁액을 얻기 위하여 스크린을 통과시켰다. 시료를 MoFlo Cell Sorter(Dako, Glostrup, Denmark) λex 568 nm 와 λem 603 nmfh 분석했고, 바탕 수준에 대하여 평균 형광 강도의 배수 증가를 계산했다. 결과는 세 개의 분리된 실험의 평균 형광을 보여준다.
진입 억제제 : 클로로프로마진(Chloropromazine)(클라트린-매개 엔도시토시스의 억제제, 10 μg/ml, 60 분); 아밀로라이드(대음세포작용 억제제, 50 μM, 30 분); 니스타틴(50 μg/ml, 30 분); 메틸-β-시클로덱스트린(MβCD, 5 mM, 60 분); 필리핀(Filipin)(카베올레-매개 엔도시토시스의 억제제, 3 μg/ml, 60 분); 탁솔(미세소관 안정화제, 20 μM, 30 분); 스타우로스포린(세포 순환 억제제, 250 nM, 10 분); 아지드화나트륨(대사억제제, 1 mM, 60 분); 오아우바인(Oauabain)(ATPase-의존성 Na+/K+ 펌프 억제제, 50 mM, 60 분); 브레펠딘 A(BFA; 골지체 교란물질, 100 μM, 60 분); 보르트만닌(Wortmannin)(초기 엔도솜 억제제, 100 nM, 30 분); 모넨신(후기 엔도솜/리소좀을 억제함, 10 μM, 60 분); 노코다졸(카베오좀 형성을 억제함, 10 μM, 60 분); 시토칼라신 D(액틴필라멘트 및 미세소관 교란물질, 5 μM, 30 분); 벤질 2-아세트아미도-2-디옥시-α-D-칼락토피라노시드(BnGalNac; 0-결합된 글리코실화 억제제, 3 mM, 48 시간); 튜니카마이신(N-결합된 글리코실화 억제제, 20 μg/ml, 48 시간); 및 뉴라민가수분해효소(단백질로부터 유래된 시알산 잔기를 쪼갬, IU/ml, 30 분)를 포함하는 억제제로 370 ℃ 조건에서 페놀레드와 혈청이 없는 MEM-E에서 유지되는 UISO-Mel-2 세포(300 μl당 3 x lO5)를 선처리했다. 최종 농도를 개개의 억제제의 투여량 반응 곡선으로부터 얻었다. 그 다음에, Alexafluor 568 표지된 pl8(서열번호:14) 또는 p28(서열번호:13)(20 μM)를 첨가했고, 1시간 동안 배양했고, 유세포분석을 위해 상술한 것처럼 세포를 세척했고, 고정했고, 준비했다.
세포막 독성 측정/ LDH 누출 측정 : lOO μl의 UISO-Mel-2 세포(5 x 103)를 사용하여 제조자의 설명(CytoTox-One, Promega, WI)에 따라서 LDH 누출 측정을 수행했다. 음성 대조군으로서 펩타이드/단백질이 없는 세포를 사용했다. 3번 반복하여 실험을 수행했다(데이터는 평균±SEM을 나타냄).
용혈 측정 : 인간 전혈 시료(2 내지 3 ml)를 1000xg로 10분 동안 원심분리했고, 펠렛을 PBS로 한번 HKR 완충액 pH 7.4( 18)로 한번 세척했다. 그 다음에, 세포 펠렛을 HKR 완충액에 재현탁시켜 4 % 적혈구가 되며, 50 μl는 950 μl의 펩타이드, 아주린(5, 50 및 100 μM) 또는 HRK 완충액 중의 0.1 % Triton X-100을 갖는 1.5 ml 튜브로 옮겨서 완전히 RBC 막을 교란했다. MAP 및 마스토파란7(Bachem California, Inc., Torrance, CA)를 양성 대조군으로 사용했다. 회전하며 37 ℃에서 30분 동안 배양한 후에, 튜브는 1000xg로 2분 동안 원심분리했고, 300 μl의 상청액을 96-웰 플레이트로 옮겼고, 540 nm에서 흡광도를 기록했다.
진입의 동역학 : 1.5 ml 튜브에서 UISO-Mel-2 세포(5 x 105 세포)를 페놀레드가 없는 MEME 배지에 현탁했다. Alexafluor 568-콘주게이션된 p18을 0, 10, 20, 50, 100, 150 및 200 μM로 5, 10, 15 및 20초 동안 첨가하거나, Alexafluor 568-콘주게이션된 p28(서열번호:13)을 1, 10, 25, 50, 100, 150 및 200 μM로 30, 60, 90 및 120초 동안 얼음에서 첨가함으로써 반응을 시작했다. 배양 후에, 1 ml의 차가운 PBS를 250 μl의 반응 혼합물에 첨가했다. 세포를 600xg로 2분 동안 4 ℃에서 2회 원심분리했다. 각각의 반응과 각각의 바탕에서 유동세포분석기는 적어도 10,000 고정된 세포를 분석했고, 상대적인 형광성을 계산했다.
아주린의 I 125 표지 및 경쟁자 측정 : 펩타이드 결합 및 진입을 UISO-Mel-2-세포를 갖는 전혈 측정을 이용하여 HEPES 용액(50,000 세포/ml)에서 확인했으며, 1000배 과잉의 미표지된 p18(서열번호:14), p28(서열번호:13) 또는 아주린의 존재/부존재에서 방사성 동위 원소로 식별된 아주린의 농도를 증가시키며(0 내지 175 nM) 37 ℃에서 30분 동안 배양했고, 이후에 얼음처럼 차가운 PBS로 3회 세척했고, 감마 카운터를 이용하여 세포 펠렛 중의 남아있는 방사성을 세었다. I125 아주린 만으로 배양된 세포 중의 방사성을 총 결합으로 간주했으며; 미표지된 아주린, p18(서열번호:14) 또는 p28(서열번호:13)의 존재하에서 방사성을 비특이적 결합으로 간주했다. 총 결합에서 비특이적 결합을 뺌으로써 특이적 결합을 결정했고, 스캐차드조사구를 만들었다.
암세포 안으로 우선적인 진입의 원인이 되는 p28 (서열번호:13)의 N-말단 도메인
펩타이드-GST 구조물로부터의 최초 데이터는 세포 침투를 위해 추정되는 PTD로서 아주린의 아미노산 50번 내지 77번을 정의했으며, 이는 아주린 분자를 안정화시키는 아주린의 54번 내지 67번 잔기를 아우르는 α-나선 영역에 대한 구조적 증거와 잘 들어맞는다. 공초점 분석은, p28/아주린의(도 6a) p28(서열번호:13) 및 p18(서열번호:14)이 비교적 비슷한 효율로 인간 흑색종, 전립선, 폐, 유방 및 난소암 세포를 침투했지만 조직학적으로 똑같은 정상 세포주를 동일한 정도로 침투하지 않는다(도 6a)는 것을 시사했다. 두드러진 예외는 폐 섬유아세포로부터 유래된 세포주인 CCD13-Lu이였다. 양이온 Arg-8(서열번호:3527)은 신속하고 효과적으로 섬유아세포 안으로 흡수되었고(도 6a) 모든 다른 정상세포주도 시험했다(데이터 미도시).
이러한 관찰은 폐암을 제외하고, 대응되는 정상 세포주보다 p28 형광이 약 0.5 내지 6배 더 높았고 p18(서열번호:14)이 약 0.5 내지 3배 높은 더 민감한 FAC 분석(도 6b)에 의해 근본적으로 확인됐다. p18(서열번호:14)의 상대적 강도가 p28(서열번호:13)에서 관찰된 것의 약 50 %였던 병리조직학적 아류형, 흑색종 내에서 세포 내의 형광 강도에 유사한 패턴을 관찰했다(도 6c). 또한, 바탕에 대한 형광 강도는 p28(서열번호:13)에 노출된 것보다 p18에 노출된 정상 및 암세포 쌍에서 일관적으로 더 낮았으며(데이터 미도시), 또 개개의 세포에 p18이 더 적게 진입한다는 것을 시사한다. 모든 경우에서, 암세포 또는 정상세포 중 어느 하나 안으로 p18(서열번호:14) 및 p28(서열번호:13)의 진입은 진입을 선호하지 않는 것으로 관찰된 Arg-8(서열번호:3527)에서 관찰된 것보다 현저히 적었다(도 6a). p18(서열번호:14)의 예상된 롭슨 구조(데이터 미도시)는 C-말단 아미노산이 부분적 β-시트를 형성한다는 것을 시사한다. p28의 친수성 C-말단으로부터 10개의 아미노산(아미노산 68번 내지 77번)이 없는 이러한 및 더 짧은 길이의 p18(서열번호:14)은 아주린에 대하여 추정되는 PTD인 p18(서열번호:14)이 비-엔도시토시스를 통해 엔도시토시스 또는 막 수용체 매개 과정을 지나 암세포와 정상세포 안으로 더 신속하게 진입할 수 있다. MAPAS 데이터(MRS 3.74, MAS 87.1, Kmpha 2.37)는 아주린의 아미노산 69번, 70번, 75번, 76번, 85번이 막접촉에 대해 가장 좋은 기회를 제공할 것으로 예측하며, p18(서열번호:14)상에 존재하지 않는(아미노산 50번 내지 67번) p28(서열번호:13)의 C-말단 영역은 세포의 상태에 개의치 않고 세포막 상에 특이적인 잔기에 접촉할 것 같다는 것을 시사한다.
p18(서열번호:14) 및 p28(서열번호:13)의 우선적인 침투는 동일한 세포주를 아주린 60번 내지 77번(p 18b)에 노출시키거나, p28의 아미노산 66번 내지 77번(p 12), p28(서열번호:13)의 C-말단으로부터 12개의 아미노산에 노출시킴으로써 확인되었다(도 7a,7b). 여기서, p18(서열번호:14)와 p28(서열번호:13)로 관찰되는 우선적인 침투는 완전히 멈추었다. p18b(서열번호:3526)(이론상 pI 4.13)은 짧은 α-나선 및 부분적인 β-시트를 갖고 있고, 이들은 함께 우선적인 진입을 효력이 없게 만들 수 있는 극친수성이다. p12(서열번호:3506)(이론상 pI 4.33)는 2차 α-나선 구조가 없지만, 이 또한 친수성이어서 전체적인 친수성은 세포 침투 선택성의 감소에 주요하게 기여할 수 있다고 시사한다.
세포침투는 막 교란의 결과가 아니다
아주린, p28(서열번호:13) 및 p18(서열번호:14)에 의한 세포침투는 막 교란으로부터의 결과가 아니다. 5 내지 100 μM p28(서열번호:13), p18(서열번호:14) 또는 아주린(도 8a)의 존재하에서 UISO-MEL-2 세포를 사용한 LDH 누출 측정은 펩타이드 뿐만 아니라 아주린도 원형질막 보전(18)을 변화시킴으로써 세포에 진입하지 않는다는 것을 시사한다. 막 교란의 결여는 세포막을 양친매성 α-나선으로 바꾸어 놓고 헤테로트리머릭(heterotimeric) G 단백질을 활성화하는 수용체 의태 MAP 및 비만세포 탈과립 펩타이드 마스토파란 7(mast cell degranulating peptide mastoparan7)에 대하여 인간 적혈구 상의 아주린, p28(서열번허:13) 및 p18(서열번호:14)의 용혈 활성을 밝힘으로써 확인되었다. 마스토파란 7은 25 μM에서 완전 세포 용해를 유발했지만, 아주린, p28(서열번호:13) 및 p18(서열번호:14)은 대조군(펩타이드 없음)에 비해 용혈 효과를 갖지 않았다(도 8b).
p18 / p28 침투는 에너지 의존성 및 포화성이다
UISO-Mel-2 세포 안으로 p28(서열번호:13)의 침투(도 9a) 및 p18(서열번호:14)의 침투(도 9b)는 온도에 의존적이다. 세포 침투 및 세포 내 수송은 4 ℃에서 3시간 넘게 비교적 천천히 발생하는 반면에, p18(서열번호:14) 및 p28(서열번호:13)이 노출 후 2시간 내에 UISO-Mel-2 세포의 핵에 존재하였기 때문에 다양한 구획을 통한 진입 및 세포 내 수송은 22 ℃와 37 ℃에서 신속하다. 200배 과잉의 미표지된 펩타이드의 존재하에서 30 분 후에 UISO-Mel-2 세포 안으로 5 μM의 p28(서열번호:13)의 침투(도 9c) 또는 5 μM의 p18(서열번호:14)의 침투(도 9d)는 대폭 단축되었으며, 이는 진입이 포화성 과정이었고, 특이적 수용체 또는 세포표면 단맥질 또는 특이적 잔기는 적어도 일부에서 최초 진입의 원인이 되었다는 것을 시사한다.
p28 (서열번호:13) 및 p18 (서열번호:14)의 동력학
세포가 고정되고, 평균 형광 강도(MFI)를 알아낸 경우에, 인간 섬유아세포와 관련된 UISO-Mel-2 세포 안으로 p28(서열번호:13) 및 p18(서열번호:14) 진입의 동력학을 배양 후에 계산했다. 각각의 펩타이드의 Km 및 Vmax를 펩타이드 농도(μM) vs. 속도(MFI/sec)로 그래프를 그려서 계산하거나 스캐차드 분석으로 계산했다. 비록 암세포 및 정상세포 안으로(각각, Vmax 2.88, Km 102.1 및 Vmax 1.89, km 166.0) 아주린 절편 50번 내지 67번(p18: Vmax 2.46, Km 101.6) 및 50 번 내지 77번(p28: Vmax 1.87, Km 159.1)의 침투는 서로 현저히 다르지만, p18(서열번호:14)은 -42 % 빠르게 진입하며, 정상세포 및 암세포 안으로 각각의 펩타이드의 진입 속도는 사실상 동등하다. 암세포를 p28(서열번호:13)에 노출시킨 후에 p18에 관한 형광의 양의 증가는 전이성 세포에 진입하는 p28(서열번호:13)의 양의 증가 때문일 것이라 생각된다. 125I 아주린 및 p18(서열번호:14)은 유사한 친화도로 UISO-Mel-2 세포에 결합했다. 이와 대조적으로, p18(서열번호:14)(Kd 18분, Bmax 0.51 pm) 또는 아주린(Kd 10 nm 및 0.48 pm) 중 어느 하나 보다 더 높은 온도(37 ℃ vs. 4 ℃)에서 더 긴 시간(20 분 vs. 2 분) 동안 노출되는 경우에, 현저히 더 많은 p28이(서열번호:13)(Kd 2.5 μm, Bmax 3.0 pm) 더 높은 친화도로 UISO-Mel-2 세포에 결합했다. 이러한 결과는 아주린, p28(서열번호:13) 및 p18(서열번호:14) 모두가 진입하기 이전에 비교적 높은 친화도 및 용량으로 암세포와 정상세포 표면상에 결합하지만, 하나 이상의 메커니즘을 통해 진입할 수 있다.
p18 / p28 침투는 카베올레 및 골지 복합체를 수반한다
전체로서는, pTat 및 Arg-8(서열번호:3527)과 같은 양이온 CPPs는 엔도시토시스 이전에 양이온 황상프로테오글리칸(sulfated proteoglycan)에 최초 결합함으로써 세포에 진입한다. 100 μg/ml 헤파린 아황산염(heparin sulfite)(HS)의 존재/부존재 중에 혈청이 없는 조건 하에서 p28(서열번호:13) 및 p18(서열번호:14)의 배양 및 UISO-Mel-2 세포와 함께 Arg-8(서열번호:3527)의 배양은 세포 내 Arg-8의 양을 현저히 감소시켰지만, p28(서열번호:13) 또는 p18(서열번호:14) 중 어느 하나의 진입을 변화시키지 않았다(도 10a). 시알산 잔기를 쪼개는 O-결합된 글리코실화, BnGalNac 및 뉴라미니다아제의 특이적 억제제의 존재 또는 부존재 중에 UISO-Mel-2 세포 안으로 p18(서열번호:14) 및 p28(서열번호:13)의 침투는 더 특정되었으며(도 10b), 침투의 억제는 관찰되지 않았다. 반면에, N-결합된 글리코실화의 억제제인 튜니카마이신은 세포막을 가로질러 p18(서열번호:14) 및 p28(서열번호:13)의 침투를 현저히 감소시켰다.
또한, UISO-Mel-2 세포 안으로 p18(서열번호:14) 및 p28(서열번호:13)의 진입을 에너지 의존 수송 메커니즘, 즉 ATP의 억제제를 사용하여 분석했다. 아지드화나트륨(도 10b) 및 와베인(Na+K+ ATPase 펌프)은 펩타이드의 침투도 현저히 억제하지 못했으며, 이는 비-엔도시토시스 경로가 이러한 펩타이드의 침투에 수반될 수도 있다는 것을 시사한다. 클라트린 매개 엔도시토시스의 특이적 억제제인 클로르프로마진(CPZ) 또한 침투에 대해 효과가 없고, 대음세포작용에도 역시 효과가 없다(도 10b). 택솔로 미소관을 안정화시키는 것은 침투에 대해 효과가 없지만, 시토칼라신 D로 액틴 필라멘트 및 대음세포작용의 교란은 p18(서열번호:14) 및 p28(서열번호:13)의 침투에 대한 작고(-20 %) 재현 가능한 억제를 초래했다. 아밀로라이드 효과의 결핍은 시토칼라신 D의 억제하는 활성이 액틴 필라멘트 상에서의 효과를 통한 것일 수 있다는 것을 시사한다.
스타우로스포린으로 세포 순환을 억제하는 것은 침투를 막지 않으며, 이는 침투가 세포 순환에 특이적이지 않다는 것을 시사한다. 또한, 암세포 원형질 막에 p18(서열번호:14) 및 p28(서열번호:13)의 침투에 대한 스타우로스포린 효과의 결핍은 Src 키나아제/티로신 키나아제 의존성 경로가 디나민 독립적인 침투에 관여되지 않기 때문에 카베올레 출아(budding)에 독립적이라는 것을 시사한다. p18(서열번호:14)도 p28(서열번호:13)도 원형질 막 내에 그리고 엔도시토시스 중간체의 특정 개체군에 존재하는 플로틸린-1(flotillin-1)(데이터 미도시) 단백질과 함께 공동 국부화되지 않았으며, 또 국재화에서 플로틸린 및 디나민의 역할에 반론을 제기한다. 그와 대조적으로, 노코다졸이 카베올레 운송 및 콜레스테롤 가동화(mobilization)의 억제제를 교란하기 때문에, 카베올레-매개 엔도시토시스는 침투를 50 내지 65 %로 억제했다.
이후에, 초기 엔도솜 형성을 억제하는 보르트만닌, 후기 엔도솜/리소좀을 억제하는 모넨신, 및 골지체를 교란하는 브레펠딘 A(BFA)를 사용하여 p18(서열번호:14) 및 p28(서열번호:13)의 세포 내 축적을 분석했다. 보르트만닌은 p18(서열번호:14) 또는 p28(서열번호:13) 중 어느 하나의 세포 내 축적을 막지 않았고, 이는 콜레라독소와 다르게 초기 엔도솜 경로에 대한 케베올레가 p18(서열번호:14) 및 p28(서열번호:13)의 세포 내 이동(trafficking)에 수반되지 않는다는 것을 시사한다. 또한, p18(서열번호:14) 및 p28(서열번호:13)의 세포 내 이동에 초기 엔도솜의 관여의 결핍은 클라트린 매개 엔도시토시스가 이러한 펩타이드의 국재화에 수반되지 않는다는 것을 시사한다.
반면에, 모넨신(도 10b) 및 BFA는 p18(서열번호:14)(~10 %)보다 p28(서열번호:13)(~30 %)에 대하여 더 큰 억제 효과를 미치는 상기 펩타이드 둘 다의 세포 내 축적을 감소시켰다. 또한, 섬유아세포 안으로 p28(서열번호:13) 및 p18(서열번호:14)의 침투는 MβCD, 노코다졸, 모넨신 및 튜니카마이신에 의해 억제되지만, 아밀로라이드, 아지드화나트륨 및 CPZ에 의해서는 억제되지 않았다(도 10c). 이는 암세포 및 정상세포 안으로 진입하는 적어도 하나의 메커니즘이 유사할 수 있지만, 암세포 안으로 부가적인 우선적 축적은 많은 보통의 막 수용체 또는 구조, 즉 카베올레의 기능일 수 있다는 것을 시사한다(도 10d, 패널 1,2). Alexafluor 568 표지된 p18(서열번호:14) 및 p28(서열번호:13)은 카베올린-1 및 골긴 97 항체와 공동 국부화됐다(도 10d, 패널 1,2). 이는 이러한 세포 기관이 p18(서열번호:14) 및 p28(서열번호:13)의 세포 내 이동에 수반된다는 것을 분명히 보여준다. 흥미로운 점은, 아주린은 미토콘드리아에 특이적인 형광을 갖도록 공동 국부화 되었지만, p18(서열번호:14)이나 p28(서열번호:13)과는 공동 국부화 되지 않았다(도 10d 패널3). 이와 대조적으로, p28(서열번호:13) 및 아주린은 리소좀과 공동 국부화되었지만, p18(서열번호:14)는 국부화되지 않았다.(도 10d, 패널 4)
p28 (서열번호:13) 및 p18 (서열번호:14)의 기능상의 분석
아주린은 몇몇의 인간 암 세포주의 시험관 내 및 생체 내 성장을 억제한다. 도 11a 및 도 11b는 MTT와 세포 수에 의해 결정되는 UISO-mel-2 세포에 대한 아주린 및 다카바진(DTIC)에 관하여 p18(서열번호:14) 및 p28(서열번호:13)의 효과를 보여준다. 72시간 노출 후에, 아주린은 세포 생존률이 100 μM 및 200 μM에서 -15 % 감소했다(p<0.05)(도 11a). p28(서열번호:13)은 세포 생존률이 100 μM 및 200 μM에서 14 및 22 %(p<0.05) 각각 억제되었다. 이와 대조적으로, p18(서열번호:14)은 효과가 없는 반면에, 다카바진(DTIC)은 UISO-Mel-2 생존에 대하여 현저한 투여량-관련된 감소를 초래했다. 또한, 아주린 및 p28(서열번호:13)(200 μM)은 UISO-mel-23 및 29 세포의 생존률을 현저히 감소시켰다. 직접적인 세포 집계(counting)에 의해 측정된, p28(서열번호:13)의 눈에 띄는 증가(~30 내지 35 %; UISO-Mel-2) 및 흑색종 세포 증식의 아주린 억제는 억제 효과가 세포 순환의 수준에서 지연 이후에 세포 사멸에 주로 속할 수 있다는 것을 시사한다. 비록 p18(서열번호:14)이 p28(서열번호:13)과 다르게 암세포를 우선적으로 침투했지만, 세포 증식에 대한 억제 활성을 거의 갖지 않았다. 이 결과는 p28(서열번호:13)의 세포 증식 억제 활성 및 세포 독성 활성이 C-말단으로부터 10번 내지 12번 아미노산 서열에 있다는 것을 증명한다.
마우스 장기 안으로 진입하는 p18 (서열번호:14) 및 p28 (서열번호:13)의 영상
생체 내에서 작은 동물의 영상은 인간 암 연구를 포함하여 생물학적 연구에 중요한 의미를 갖는다. 표지된 생물학적 프로브를 추적하고 시각화하는 능력은 연구자가 생물학적 과정을 시각화하고, 작용 및 효능의 메커니즘을 추론할 수 있게 한다. 영상화는 아주린 및 아주린 절편 p28(서열번호:13)과 p18(서열번호:14)을 포함하는 단백질의 큐프레독신 부류의 근적외선 표지된 펩타이드를 이종이식 받은 누드마우스의 초기 및 전이성 종양 부위로 이동하는 것을 직접적으로 시각화하기 위해 사용될 수 있다(J Biomed Optics 10:054010-1-11, 2005; J Amer Soc Exp Neuother 2:215-225, 2005; Topics Curr Chem 222:1-29, 2002).
절차. Mel2 이종이식 종양을 지닌 흉선이 제거된 마우스를 종양 크기가 0.5 cm3에 도달할 때까지 관찰했다. 마우스를 2:1로 케타민:자일라진를 혼합한 혼합물을 사용하여 마취했으며; 피하에 권고 투여량은 마우스 체중에 대하여 10 μl/gm 이다. 마취된 마우스를 표지된 페베타이드의 주입 직전과 직후에 iCor Odyssey Imager를 사용하여 검사했다. 마취된 마우스의 미정맥 안으로 100 μl의 IRDyeTM 800cw 표지된 p18/p28을 각 마우스당 1.25 μg/μl 내지 125 μg의 농도로 주입했다. 과잉 염료가 시스템에서 제거될 때까지(보통 ~5일) 24시간에 적어도 한번 마우스를 검사했다. 5일째에, 마우스를 죽였고, 각각의 동물을 마지막으로 검사했다. 신장, 위, 장, 비장, 뇌, 심장 및 폐를 포함하는 장기 및 종양을 절개했으며, 반으로 쪼개고, 절반을 조직학적 검사를 위해 고정했다. 장기 및 종양의 다른 절반을 소량의 PBS로 덮은 후에 검사했다.
SEQUENCE LISTING <110> DAS GUPTA, TAPAS K. BEATTIE, CRAIG W. <120> MODIFICATIONS OF CUPREDOXIN DERIVED PEPTIDES AND METHODS OF USE THEREOF <130> 14PR-141879 <140> 12/389,120 <141> 2009-02-19 <150> 12/314,703 <151> 2008-12-15 <150> 61/013,709 <151> 2007-12-14 <150> 11/853,497 <151> 2007-09-11 <150> 60/843,388 <151> 2006-09-11 <150> 11/244,105 <151> 2005-10-06 <150> 60/616,782 <151> 2004-10-07 <150> 60/680,500 <151> 2005-05-13 <150> 60/700,297 <151> 2005-07-19 <160> 3531 <170> PatentIn version 3.5 <210> 1 <400> 1 000 <210> 2 <400> 2 000 <210> 3 <400> 3 000 <210> 4 <400> 4 000 <210> 5 <400> 5 000 <210> 6 <400> 6 000 <210> 7 <400> 7 000 <210> 8 <400> 8 000 <210> 9 <400> 9 000 <210> 10 <400> 10 000 <210> 11 <400> 11 000 <210> 12 <400> 12 000 <210> 13 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 13 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 14 <211> 18 <212> PRT <213> Pseudomonas aeruginosa <400> 14 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly <210> 15 <400> 15 000 <210> 16 <400> 16 000 <210> 17 <400> 17 000 <210> 18 <400> 18 000 <210> 19 <211> 17 <212> PRT <213> Pseudomonas aeruginosa <400> 19 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser <210> 20 <211> 11 <212> PRT <213> Pseudomonas aeruginosa <400> 20 Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 1 5 10 <210> 21 <400> 21 000 <210> 22 <400> 22 000 <210> 23 <400> 23 000 <210> 24 <211> 18 <212> PRT <213> Pseudomonas aeruginosa <400> 24 Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala Ser Gly Leu 1 5 10 15 Asp Lys <210> 25 <211> 12 <212> PRT <213> Pseudomonas aeruginosa <400> 25 Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met 1 5 10 <210> 26 <211> 27 <212> PRT <213> Pseudomonas aeruginosa <400> 26 Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala Ser 1 5 10 15 Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 27 <400> 27 000 <210> 28 <400> 28 000 <210> 29 <400> 29 000 <210> 30 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 30 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 31 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 31 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 32 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 32 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 33 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 33 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 34 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 34 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 35 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 35 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 36 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 36 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 37 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 37 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 38 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 38 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 39 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 39 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 40 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 40 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 41 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 41 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 42 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 42 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 43 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 43 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 44 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 44 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 45 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 45 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 46 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <221> MOD_RES <222> (3)..(7) <223> Any amino acid <220> <221> MOD_RES <222> (9)..(10) <223> Any amino acid <220> <221> MOD_RES <222> (12)..(12) <223> Any amino acid <220> <221> MOD_RES <222> (14)..(15) <223> Any amino acid <400> 46 Asp Gly Xaa Xaa Xaa Xaa Xaa Asp Xaa Xaa Tyr Xaa Lys Xaa Xaa Asp 1 5 10 15 <210> 47 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <221> MOD_RES <222> (3)..(6) <223> Any amino acid <220> <221> MOD_RES <222> (8)..(9) <223> Any amino acid <220> <221> MOD_RES <222> (11)..(11) <223> Any amino acid <220> <221> MOD_RES <222> (13)..(14) <223> Any amino acid <400> 47 Asp Gly Xaa Xaa Xaa Xaa Asp Xaa Xaa Tyr Xaa Lys Xaa Xaa Asp 1 5 10 15 <210> 48 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <221> MOD_RES <222> (1)..(1) <223> Leu or acetylated-Leu <220> <221> MOD_RES <222> (3)..(3) <223> Thr or Trp <220> <221> MOD_RES <222> (7)..(7) <223> Met, Leu or Val <220> <221> MOD_RES <222> (8)..(8) <223> Gln or Trp <220> <221> MOD_RES <222> (9)..(9) <223> Gly or Ala <220> <221> MOD_RES <222> (12)..(12) <223> Thr or Trp <220> <221> MOD_RES <222> (14)..(14) <223> Gly, Thr or Trp <220> <221> MOD_RES <222> (15)..(15) <223> Met, Leu or Val <220> <221> MOD_RES <222> (28)..(28) <223> Asp or amidated-Asp <400> 48 Xaa Ser Xaa Ala Ala Asp Xaa Xaa Xaa Val Val Xaa Asp Xaa Xaa Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Xaa 20 25 <210> 49 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <221> MOD_RES <222> (1)..(1) <223> Asp or acetylated-Asp <220> <221> MOD_RES <222> (14)..(14) <223> Met, Leu or Val <220> <221> MOD_RES <222> (15)..(15) <223> Gly, Thr or Trp <220> <221> MOD_RES <222> (17)..(17) <223> Thr or Trp <220> <221> MOD_RES <222> (20)..(20) <223> Gly or Ala <220> <221> MOD_RES <222> (21)..(21) <223> Gln or Trp <220> <221> MOD_RES <222> (22)..(22) <223> Met, Leu or Val <220> <221> MOD_RES <222> (26)..(26) <223> Thr or Trp <220> <221> MOD_RES <222> (28)..(28) <223> Leu or amidated-Leu <400> 49 Xaa Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Xaa Xaa Asp 1 5 10 15 Xaa Val Val Xaa Xaa Xaa Asp Ala Ala Xaa Ser Xaa 20 25 <210> 50 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 50 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 51 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 51 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 52 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 52 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 53 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 53 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 54 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 54 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 55 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 55 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 56 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 56 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 57 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 57 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 58 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 58 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 59 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 59 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 60 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 60 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 61 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 61 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 62 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 62 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 63 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 63 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 64 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 64 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 65 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 65 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 66 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 66 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 67 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 67 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 68 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 68 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 69 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 69 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 70 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 70 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 71 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 71 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 72 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 72 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 73 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 73 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 74 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 74 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 75 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 75 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 76 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 76 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 77 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 77 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 78 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 78 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 79 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 79 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 80 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 80 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 81 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 81 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 82 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 82 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 83 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 83 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 84 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 84 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 85 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 85 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 86 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 86 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 87 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 87 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 88 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 88 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 89 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 89 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 90 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 90 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 91 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 91 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 92 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 92 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 93 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 93 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 94 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 94 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 95 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 95 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 96 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 96 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 97 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 97 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 98 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 98 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 99 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 99 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 100 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 100 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 101 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 101 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 102 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 102 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 103 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 103 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 104 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 104 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 105 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 105 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 106 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 106 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 107 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 107 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 108 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 108 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 109 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 109 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 110 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 110 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 111 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 111 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 112 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 112 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 113 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 113 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 114 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 114 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 115 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 115 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 116 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 116 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 117 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 117 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 118 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 118 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 119 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 119 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 120 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 120 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 121 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 121 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 122 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 122 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 123 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 123 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 124 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 124 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 125 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 125 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 126 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 126 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 127 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 127 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 128 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 128 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 129 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 129 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 130 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 130 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 131 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 131 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 132 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 132 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 133 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 133 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 134 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 134 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 135 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 135 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 136 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 136 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 137 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 137 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 138 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 138 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 139 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 139 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 140 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 140 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 141 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 141 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 142 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 142 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 143 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 143 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 144 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 144 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 145 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 145 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 146 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 146 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 147 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 147 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 148 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 148 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 149 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 149 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 150 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 150 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 151 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 151 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 152 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 152 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 153 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 153 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 154 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 154 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 155 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 155 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 156 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 156 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 157 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 157 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 158 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 158 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 159 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 159 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 160 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 160 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 161 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 161 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 162 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 162 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 163 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 163 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 164 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 164 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 165 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 165 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 166 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 166 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 167 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 167 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 168 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 168 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 169 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 169 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 170 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 170 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 171 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 171 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 172 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 172 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 173 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 173 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 174 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 174 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 175 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 175 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 176 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 176 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 177 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 177 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 178 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 178 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 179 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 179 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 180 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 180 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 181 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 181 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 182 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 182 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 183 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 183 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 184 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 184 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 185 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 185 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 186 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 186 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 187 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 187 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 188 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 188 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 189 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 189 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 190 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 190 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 191 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 191 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 192 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 192 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 193 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 193 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 194 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 194 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 195 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 195 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 196 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 196 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 197 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 197 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 198 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 198 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 199 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 199 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 200 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 200 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 201 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 201 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 202 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 202 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 203 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 203 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 204 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 204 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 205 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 205 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 206 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 206 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 207 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 207 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 208 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 208 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 209 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 209 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 210 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 210 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 211 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 211 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 212 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 212 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 213 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 213 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 214 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 214 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 215 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 215 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 216 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 216 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 217 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 217 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 218 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 218 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 219 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 219 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 220 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 220 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 221 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 221 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 222 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 222 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 223 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 223 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 224 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 224 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 225 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 225 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 226 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 226 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 227 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 227 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 228 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 228 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 229 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 229 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 230 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 230 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 231 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 231 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 232 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 232 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 233 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 233 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 234 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 234 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 235 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 235 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 236 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 236 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 237 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 237 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 238 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 238 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 239 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 239 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 240 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 240 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 241 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 241 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 242 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 242 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 243 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 243 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 244 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 244 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 245 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 245 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 246 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 246 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 247 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 247 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 248 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 248 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 249 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 249 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 250 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 250 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 251 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 251 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 252 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 252 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 253 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 253 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 254 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 254 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 255 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 255 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 256 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 256 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 257 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 257 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 258 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 258 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 259 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 259 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 260 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 260 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 261 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 261 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 262 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 262 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 263 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 263 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 264 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 264 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 265 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 265 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 266 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 266 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 267 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 267 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 268 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 268 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 269 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 269 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 270 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 270 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 271 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 271 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 272 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 272 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 273 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 273 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 274 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 274 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 275 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 275 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 276 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 276 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 277 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 277 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 278 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 278 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 279 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 279 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 280 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 280 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 281 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 281 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 282 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 282 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 283 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 283 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 284 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 284 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 285 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 285 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 286 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 286 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 287 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 287 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 288 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 288 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 289 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 289 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 290 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 290 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 291 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 291 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 292 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 292 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 293 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 293 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 294 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 294 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 295 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 295 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 296 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 296 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 297 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 297 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 298 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 298 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 299 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 299 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 300 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 300 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 301 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 301 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 302 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 302 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 303 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 303 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 304 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 304 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 305 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 305 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 306 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 306 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 307 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 307 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 308 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 308 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 309 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 309 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 310 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 310 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 311 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 311 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 312 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 312 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 313 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 313 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 314 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 314 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 315 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 315 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 316 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 316 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 317 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 317 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 318 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 318 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 319 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 319 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 320 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 320 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 321 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 321 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 322 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 322 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 323 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 323 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 324 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 324 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 325 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 325 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 326 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 326 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 327 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 327 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 328 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 328 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 329 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 329 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 330 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 330 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 331 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 331 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 332 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 332 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 333 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 333 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 334 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 334 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 335 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 335 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 336 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 336 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 337 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 337 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 338 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 338 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 339 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 339 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 340 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 340 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 341 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 341 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 342 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 342 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 343 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 343 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 344 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 344 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 345 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 345 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 346 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 346 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 347 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 347 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 348 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 348 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 349 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 349 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 350 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 350 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 351 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 351 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 352 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 352 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 353 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 353 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 354 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 354 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 355 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 355 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 356 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 356 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 357 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 357 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 358 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 358 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 359 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 359 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 360 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 360 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 361 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 361 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 362 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 362 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 363 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 363 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 364 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 364 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 365 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 365 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 366 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 366 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 367 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 367 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 368 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 368 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 369 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 369 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 370 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 370 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 371 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 371 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 372 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 372 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 373 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 373 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 374 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 374 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 375 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 375 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 376 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 376 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 377 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 377 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 378 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 378 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 379 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 379 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 380 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 380 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 381 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 381 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 382 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 382 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 383 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 383 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 384 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 384 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 385 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 385 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 386 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 386 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 387 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 387 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 388 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 388 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 389 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 389 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 390 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 390 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 391 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 391 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 392 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 392 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 393 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 393 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 394 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 394 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 395 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 395 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 396 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 396 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 397 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 397 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 398 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 398 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 399 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 399 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 400 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 400 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 401 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 401 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 402 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 402 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 403 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 403 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 404 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 404 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 405 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 405 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 406 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 406 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 407 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 407 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 408 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 408 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 409 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 409 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 410 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 410 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 411 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 411 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 412 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 412 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 413 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 413 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 414 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 414 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 415 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 415 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 416 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 416 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 417 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 417 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 418 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 418 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 419 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 419 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 420 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 420 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 421 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 421 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 422 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 422 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 423 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 423 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 424 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 424 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 425 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 425 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 426 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 426 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 427 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 427 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 428 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 428 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 429 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 429 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 430 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 430 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 431 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 431 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 432 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 432 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 433 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 433 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 434 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 434 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 435 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 435 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 436 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 436 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 437 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 437 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 438 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 438 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 439 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 439 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 440 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 440 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 441 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 441 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 442 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 442 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 443 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 443 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 444 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 444 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 445 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 445 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 446 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 446 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 447 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 447 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 448 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 448 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 449 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 449 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 450 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 450 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 451 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 451 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 452 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 452 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 453 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 453 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 454 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 454 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 455 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 455 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 456 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 456 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 457 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 457 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 458 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 458 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 459 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 459 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 460 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 460 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 461 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 461 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 462 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 462 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 463 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 463 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 464 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 464 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 465 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 465 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 466 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 466 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 467 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 467 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 468 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 468 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 469 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 469 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 470 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 470 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 471 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 471 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 472 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 472 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 473 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 473 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 474 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 474 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 475 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 475 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 476 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 476 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 477 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 477 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 478 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 478 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 479 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 479 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 480 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 480 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 481 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 481 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 482 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 482 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 483 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 483 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 484 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 484 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 485 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 485 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 486 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 486 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 487 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 487 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 488 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 488 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 489 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 489 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 490 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 490 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 491 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 491 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 492 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 492 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 493 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 493 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 494 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 494 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 495 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 495 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 496 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 496 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 497 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 497 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 498 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 498 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 499 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 499 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 500 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 500 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 501 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 501 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 502 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 502 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 503 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 503 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 504 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 504 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 505 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 505 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 506 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 506 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 507 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 507 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 508 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 508 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 509 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 509 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 510 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 510 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 511 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 511 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 512 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 512 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 513 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 513 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 514 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 514 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 515 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 515 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 516 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 516 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 517 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 517 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 518 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 518 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 519 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 519 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 520 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 520 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 521 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 521 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 522 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 522 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 523 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 523 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 524 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 524 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 525 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 525 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 526 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 526 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 527 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 527 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 528 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 528 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 529 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 529 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 530 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 530 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 531 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 531 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 532 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 532 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 533 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 533 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 534 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 534 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 535 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 535 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 536 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 536 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 537 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 537 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 538 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 538 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 539 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 539 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 540 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 540 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 541 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 541 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 542 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 542 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 543 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 543 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 544 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 544 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 545 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 545 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 546 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 546 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 547 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 547 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 548 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 548 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 549 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 549 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 550 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 550 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 551 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 551 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 552 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 552 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 553 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 553 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 554 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 554 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 555 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 555 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 556 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 556 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 557 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 557 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 558 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 558 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 559 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 559 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 560 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 560 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 561 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 561 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 562 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 562 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 563 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 563 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 564 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 564 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 565 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 565 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 566 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 566 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 567 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 567 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 568 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 568 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 569 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 569 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 570 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 570 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 571 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 571 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 572 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 572 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 573 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 573 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 574 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 574 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 575 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 575 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 576 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 576 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 577 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 577 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 578 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 578 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 579 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 579 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 580 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 580 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 581 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 581 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 582 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 582 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 583 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 583 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 584 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 584 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 585 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 585 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 586 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 586 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 587 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 587 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 588 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 588 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 589 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 589 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 590 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 590 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 591 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 591 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 592 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 592 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 593 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 593 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 594 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 594 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 595 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 595 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 596 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 596 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 597 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 597 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 598 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 598 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 599 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 599 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 600 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 600 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 601 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 601 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 602 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 602 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 603 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 603 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 604 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 604 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 605 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 605 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 606 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 606 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 607 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 607 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 608 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 608 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 609 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 609 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 610 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 610 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 611 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 611 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 612 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 612 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 613 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 613 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 614 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 614 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 615 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 615 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 616 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 616 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 617 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 617 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 618 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 618 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 619 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 619 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 620 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 620 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 621 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 621 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 622 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 622 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 623 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 623 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 624 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 624 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 625 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 625 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 626 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 626 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 627 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 627 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 628 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 628 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 629 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 629 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 630 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 630 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 631 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 631 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 632 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 632 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 633 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 633 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 634 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 634 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 635 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 635 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 636 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 636 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 637 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 637 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 638 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 638 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 639 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 639 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 640 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 640 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 641 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 641 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 642 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 642 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 643 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 643 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 644 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 644 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 645 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 645 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 646 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 646 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 647 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 647 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 648 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 648 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 649 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 649 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 650 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 650 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 651 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 651 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 652 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 652 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 653 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 653 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 654 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 654 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 655 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 655 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 656 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 656 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 657 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 657 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 658 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 658 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 659 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 659 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 660 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 660 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 661 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 661 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 662 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 662 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 663 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 663 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 664 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 664 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 665 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 665 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 666 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 666 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 667 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 667 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 668 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 668 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 669 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 669 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 670 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 670 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 671 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 671 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 672 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 672 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 673 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 673 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 674 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 674 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 675 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 675 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 676 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 676 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 677 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 677 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 678 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 678 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 679 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 679 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 680 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 680 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 681 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 681 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 682 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 682 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 683 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 683 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 684 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 684 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 685 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 685 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 686 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 686 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 687 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 687 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 688 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 688 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 689 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 689 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 690 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 690 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 691 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 691 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 692 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 692 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 693 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 693 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 694 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 694 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 695 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 695 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 696 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 696 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 697 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 697 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 698 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 698 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 699 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 699 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 700 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 700 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 701 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 701 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 702 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 702 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 703 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 703 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 704 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 704 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 705 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 705 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 706 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 706 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 707 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 707 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 708 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 708 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 709 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 709 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 710 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 710 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 711 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 711 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 712 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 712 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 713 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 713 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 714 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 714 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 715 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 715 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 716 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 716 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 717 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 717 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 718 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 718 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 719 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 719 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 720 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 720 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 721 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 721 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 722 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 722 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 723 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 723 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 724 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 724 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 725 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 725 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 726 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 726 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 727 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 727 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 728 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 728 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 729 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 729 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 730 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 730 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 731 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 731 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 732 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 732 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 733 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 733 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 734 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 734 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 735 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 735 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 736 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 736 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 737 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 737 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 738 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 738 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 739 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 739 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 740 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 740 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 741 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 741 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 742 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 742 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 743 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 743 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 744 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 744 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 745 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 745 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 746 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 746 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 747 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 747 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 748 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 748 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 749 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 749 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 750 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 750 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 751 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 751 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 752 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 752 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 753 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 753 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 754 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 754 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 755 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 755 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 756 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 756 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 757 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 757 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 758 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 758 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 759 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 759 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 760 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 760 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 761 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 761 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 762 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 762 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 763 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 763 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 764 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 764 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 765 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 765 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 766 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 766 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 767 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 767 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 768 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 768 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 769 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 769 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 770 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 770 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 771 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 771 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 772 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 772 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 773 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 773 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 774 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 774 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 775 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 775 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 776 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 776 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 777 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 777 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 778 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 778 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 779 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 779 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 780 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 780 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 781 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 781 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 782 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 782 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 783 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 783 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 784 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 784 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 785 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 785 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 786 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 786 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 787 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 787 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 788 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 788 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 789 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 789 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 790 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 790 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 791 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 791 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 792 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 792 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 793 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 793 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 794 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 794 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 795 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 795 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 796 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 796 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 797 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 797 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 798 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 798 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 799 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 799 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 800 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 800 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 801 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 801 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 802 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 802 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 803 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 803 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 804 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 804 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 805 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 805 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 806 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 806 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 807 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 807 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 808 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 808 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 809 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 809 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 810 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 810 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 811 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 811 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 812 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 812 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 813 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 813 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 814 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 814 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 815 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 815 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 816 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 816 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 817 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 817 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 818 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 818 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 819 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 819 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 820 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 820 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 821 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 821 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 822 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 822 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 823 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 823 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 824 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 824 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 825 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 825 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 826 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 826 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 827 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 827 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 828 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 828 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 829 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 829 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 830 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 830 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 831 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 831 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 832 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 832 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 833 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 833 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 834 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 834 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 835 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 835 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 836 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 836 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 837 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 837 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 838 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 838 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 839 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 839 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 840 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 840 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 841 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 841 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 842 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 842 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 843 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 843 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 844 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 844 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 845 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 845 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 846 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 846 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 847 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 847 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 848 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 848 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 849 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 849 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 850 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 850 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 851 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 851 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 852 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 852 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 853 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 853 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 854 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 854 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 855 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 855 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 856 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 856 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 857 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 857 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 858 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 858 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 859 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 859 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 860 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 860 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 861 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 861 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 862 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 862 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 863 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 863 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 864 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 864 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 865 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 865 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 866 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 866 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 867 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 867 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 868 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 868 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 869 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 869 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 870 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 870 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 871 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 871 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 872 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 872 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 873 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 873 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 874 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 874 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 875 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 875 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 876 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 876 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 877 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 877 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 878 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 878 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 879 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 879 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 880 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 880 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 881 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 881 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 882 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 882 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 883 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 883 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 884 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 884 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 885 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 885 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 886 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 886 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 887 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 887 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 888 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 888 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 889 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 889 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 890 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 890 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 891 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 891 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 892 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 892 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 893 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 893 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 894 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 894 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 895 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 895 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 896 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 896 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 897 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 897 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 898 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 898 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 899 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 899 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 900 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 900 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 901 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 901 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 902 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 902 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 903 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 903 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 904 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 904 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 905 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 905 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 906 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 906 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 907 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 907 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 908 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 908 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 909 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 909 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 910 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 910 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 911 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 911 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 912 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 912 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 913 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 913 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 914 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 914 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 915 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 915 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 916 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 916 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 917 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 917 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 918 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 918 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 919 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 919 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 920 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 920 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 921 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 921 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 922 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 922 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 923 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 923 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 924 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 924 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 925 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 925 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 926 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 926 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 927 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 927 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 928 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 928 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 929 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 929 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 930 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 930 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 931 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 931 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 932 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 932 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 933 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 933 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 934 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 934 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 935 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 935 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 936 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 936 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 937 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 937 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 938 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 938 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 939 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 939 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 940 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 940 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 941 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 941 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 942 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 942 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 943 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 943 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 944 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 944 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 945 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 945 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 946 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 946 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 947 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 947 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 948 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 948 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 949 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 949 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 950 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 950 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 951 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 951 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 952 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 952 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 953 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 953 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 954 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 954 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 955 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 955 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 956 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 956 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 957 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 957 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 958 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 958 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 959 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 959 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 960 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 960 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 961 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 961 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 962 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 962 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 963 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 963 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 964 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 964 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 965 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 965 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 966 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 966 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 967 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 967 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 968 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 968 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 969 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 969 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 970 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 970 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 971 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 971 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 972 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 972 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 973 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 973 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 974 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 974 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 975 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 975 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 976 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 976 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 977 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 977 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 978 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 978 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 979 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 979 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 980 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 980 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 981 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 981 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 982 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 982 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 983 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 983 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 984 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 984 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 985 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 985 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 986 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 986 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 987 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 987 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 988 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 988 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 989 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 989 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 990 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 990 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 991 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 991 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 992 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 992 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 993 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 993 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 994 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 994 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 995 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 995 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 996 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 996 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 997 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 997 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 998 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 998 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 999 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 999 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1000 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1000 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1001 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1001 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1002 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1002 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1003 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1003 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1004 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1004 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1005 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1005 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1006 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1006 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1007 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1007 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1008 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1008 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1009 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1009 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1010 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1010 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1011 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1011 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1012 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1012 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1013 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1013 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1014 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1014 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1015 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1015 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1016 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1016 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1017 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1017 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1018 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1018 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1019 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1019 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1020 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1020 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1021 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1021 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1022 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1022 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1023 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1023 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1024 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1024 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1025 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1025 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1026 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1026 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1027 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1027 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1028 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1028 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1029 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1029 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1030 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1030 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1031 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1031 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1032 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1032 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1033 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1033 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1034 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1034 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1035 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1035 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1036 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1036 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1037 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1037 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1038 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1038 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1039 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1039 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1040 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1040 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1041 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1041 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1042 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1042 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1043 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1043 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1044 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1044 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1045 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1045 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1046 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1046 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1047 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1047 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1048 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1048 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1049 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1049 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1050 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1050 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1051 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1051 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1052 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1052 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1053 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1053 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1054 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1054 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1055 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1055 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1056 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1056 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1057 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1057 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1058 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1058 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1059 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1059 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1060 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1060 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1061 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1061 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1062 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1062 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1063 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1063 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1064 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1064 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1065 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1065 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1066 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1066 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1067 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1067 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1068 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1068 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1069 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1069 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1070 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1070 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1071 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1071 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1072 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1072 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1073 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1073 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1074 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1074 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1075 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1075 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1076 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1076 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1077 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1077 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1078 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1078 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1079 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1079 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1080 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1080 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1081 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1081 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1082 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1082 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1083 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1083 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1084 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1084 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1085 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1085 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1086 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1086 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1087 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1087 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1088 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1088 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1089 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1089 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1090 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1090 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1091 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1091 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1092 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1092 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1093 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1093 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1094 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1094 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1095 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1095 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1096 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1096 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1097 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1097 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1098 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1098 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1099 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1099 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1100 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1100 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1101 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1101 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1102 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1102 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1103 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1103 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1104 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1104 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1105 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1105 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1106 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1106 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1107 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1107 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1108 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1108 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1109 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1109 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1110 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1110 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1111 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1111 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1112 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1112 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1113 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1113 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1114 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1114 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1115 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1115 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1116 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1116 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1117 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1117 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1118 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1118 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1119 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1119 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1120 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1120 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1121 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1121 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1122 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1122 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1123 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1123 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1124 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1124 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1125 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1125 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1126 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1126 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1127 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1127 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1128 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1128 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1129 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1129 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1130 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1130 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1131 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1131 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1132 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1132 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1133 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1133 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1134 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1134 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1135 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1135 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1136 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1136 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1137 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1137 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1138 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1138 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1139 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1139 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1140 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1140 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1141 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1141 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1142 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1142 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1143 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1143 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1144 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1144 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1145 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1145 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1146 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1146 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1147 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1147 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1148 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1148 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1149 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1149 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1150 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1150 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1151 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1151 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1152 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1152 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1153 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1153 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1154 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1154 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1155 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1155 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1156 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1156 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1157 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1157 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1158 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1158 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1159 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1159 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1160 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1160 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1161 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1161 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1162 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1162 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1163 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1163 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1164 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1164 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1165 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1165 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1166 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1166 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1167 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1167 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1168 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1168 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1169 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1169 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1170 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1170 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1171 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1171 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1172 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1172 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1173 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1173 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1174 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1174 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1175 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1175 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1176 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1176 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1177 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1177 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1178 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1178 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1179 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1179 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1180 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1180 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1181 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1181 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1182 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1182 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1183 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1183 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1184 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1184 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1185 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1185 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1186 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1186 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1187 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1187 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1188 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1188 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1189 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1189 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1190 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1190 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1191 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1191 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1192 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1192 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1193 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1193 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1194 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1194 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1195 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1195 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1196 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1196 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1197 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1197 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1198 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1198 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1199 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1199 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1200 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1200 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1201 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1201 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1202 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1202 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1203 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1203 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1204 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1204 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1205 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1205 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1206 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1206 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1207 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1207 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1208 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1208 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1209 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1209 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1210 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1210 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1211 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1211 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1212 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1212 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1213 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1213 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1214 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1214 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1215 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1215 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1216 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1216 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1217 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1217 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1218 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1218 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1219 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1219 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1220 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1220 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1221 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1221 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1222 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1222 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1223 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1223 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1224 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1224 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1225 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1225 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1226 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1226 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1227 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1227 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1228 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1228 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1229 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1229 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1230 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1230 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1231 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1231 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1232 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1232 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1233 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1233 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1234 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1234 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1235 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1235 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1236 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1236 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1237 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1237 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1238 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1238 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1239 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1239 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1240 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1240 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1241 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1241 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1242 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1242 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1243 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1243 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1244 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1244 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1245 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1245 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1246 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1246 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1247 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1247 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1248 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1248 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1249 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1249 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1250 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1250 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1251 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1251 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1252 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1252 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1253 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1253 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1254 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1254 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1255 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1255 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1256 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1256 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1257 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1257 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1258 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1258 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1259 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1259 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1260 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1260 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1261 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1261 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1262 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1262 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1263 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1263 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1264 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1264 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1265 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1265 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1266 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1266 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1267 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1267 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1268 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1268 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1269 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1269 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1270 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1270 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1271 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1271 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1272 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1272 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1273 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1273 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1274 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1274 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1275 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1275 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1276 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1276 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1277 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1277 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1278 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1278 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1279 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1279 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1280 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1280 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1281 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1281 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1282 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1282 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1283 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1283 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1284 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1284 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1285 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1285 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1286 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1286 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1287 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1287 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1288 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1288 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1289 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1289 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1290 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1290 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1291 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1291 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1292 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1292 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1293 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1293 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1294 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1294 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1295 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1295 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1296 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1296 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1297 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1297 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1298 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1298 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1299 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1299 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1300 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1300 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1301 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1301 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1302 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1302 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1303 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1303 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1304 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1304 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1305 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1305 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1306 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1306 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1307 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1307 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1308 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1308 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1309 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1309 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1310 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1310 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1311 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1311 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1312 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1312 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1313 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1313 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1314 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1314 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1315 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1315 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1316 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1316 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1317 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1317 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1318 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1318 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1319 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1319 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1320 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1320 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1321 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1321 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1322 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1322 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1323 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1323 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1324 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1324 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1325 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1325 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1326 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1326 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1327 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1327 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1328 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1328 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1329 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1329 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1330 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1330 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1331 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1331 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1332 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1332 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1333 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1333 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1334 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1334 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1335 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1335 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1336 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1336 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1337 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1337 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1338 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1338 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1339 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1339 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1340 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1340 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1341 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1341 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1342 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1342 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1343 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1343 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1344 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1344 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1345 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1345 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1346 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1346 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1347 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1347 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1348 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1348 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1349 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1349 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1350 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1350 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1351 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1351 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1352 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1352 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1353 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1353 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1354 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1354 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1355 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1355 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1356 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1356 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1357 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1357 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1358 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1358 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1359 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1359 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1360 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1360 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1361 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1361 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1362 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1362 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1363 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1363 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1364 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1364 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1365 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1365 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1366 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1366 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1367 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1367 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1368 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1368 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1369 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1369 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1370 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1370 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1371 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1371 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1372 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1372 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1373 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1373 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1374 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1374 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1375 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1375 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1376 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1376 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1377 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1377 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1378 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1378 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1379 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1379 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1380 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1380 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1381 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1381 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1382 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1382 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1383 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1383 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1384 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1384 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1385 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1385 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1386 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1386 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1387 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1387 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1388 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1388 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1389 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1389 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1390 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1390 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1391 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1391 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1392 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1392 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1393 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1393 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1394 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1394 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1395 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1395 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1396 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1396 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1397 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1397 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1398 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1398 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1399 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1399 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1400 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1400 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1401 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1401 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1402 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1402 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1403 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1403 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1404 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1404 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1405 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1405 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1406 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1406 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1407 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1407 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1408 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1408 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1409 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1409 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1410 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1410 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1411 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1411 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1412 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1412 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1413 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1413 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1414 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1414 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1415 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1415 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1416 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1416 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1417 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1417 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1418 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1418 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1419 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1419 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1420 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1420 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1421 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1421 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1422 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1422 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1423 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1423 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1424 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1424 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1425 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1425 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1426 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1426 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1427 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1427 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1428 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1428 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1429 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1429 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1430 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1430 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1431 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1431 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1432 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1432 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1433 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1433 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1434 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1434 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1435 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1435 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1436 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1436 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1437 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1437 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1438 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1438 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1439 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1439 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1440 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1440 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1441 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1441 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1442 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1442 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1443 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1443 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1444 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1444 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1445 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1445 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1446 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1446 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1447 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1447 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1448 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1448 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1449 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1449 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1450 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1450 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1451 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1451 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1452 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1452 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1453 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1453 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1454 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1454 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1455 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1455 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1456 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1456 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1457 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1457 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1458 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1458 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1459 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1459 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1460 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1460 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1461 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1461 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1462 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1462 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1463 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1463 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1464 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1464 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1465 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1465 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1466 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1466 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1467 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1467 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1468 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1468 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1469 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1469 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1470 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1470 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1471 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1471 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1472 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1472 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1473 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1473 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1474 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1474 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1475 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1475 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1476 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1476 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1477 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1477 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1478 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1478 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1479 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1479 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1480 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1480 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1481 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1481 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1482 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1482 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1483 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1483 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1484 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1484 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1485 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1485 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1486 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1486 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1487 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1487 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1488 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1488 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1489 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1489 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1490 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1490 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1491 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1491 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1492 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1492 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1493 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1493 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1494 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1494 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1495 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1495 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1496 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1496 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1497 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1497 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1498 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1498 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1499 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1499 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1500 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1500 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1501 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1501 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1502 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1502 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1503 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1503 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1504 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1504 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1505 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1505 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1506 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1506 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1507 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1507 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1508 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1508 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1509 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1509 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1510 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1510 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1511 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1511 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1512 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1512 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1513 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1513 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1514 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1514 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1515 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1515 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1516 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1516 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1517 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1517 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1518 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1518 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1519 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1519 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1520 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1520 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1521 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1521 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1522 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1522 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1523 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1523 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1524 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1524 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1525 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1525 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1526 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1526 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1527 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1527 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1528 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1528 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1529 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1529 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1530 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1530 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1531 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1531 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1532 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1532 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1533 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1533 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1534 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1534 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1535 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1535 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1536 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1536 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1537 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1537 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1538 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1538 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1539 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1539 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1540 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1540 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1541 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1541 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1542 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1542 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1543 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1543 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1544 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1544 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1545 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1545 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1546 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1546 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1547 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1547 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1548 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1548 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1549 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1549 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1550 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1550 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1551 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1551 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1552 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1552 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1553 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1553 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1554 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1554 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1555 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1555 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1556 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1556 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1557 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1557 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1558 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1558 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1559 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1559 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1560 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1560 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1561 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1561 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1562 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1562 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1563 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1563 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1564 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1564 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1565 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1565 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1566 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1566 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1567 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1567 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1568 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1568 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1569 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1569 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1570 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1570 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1571 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1571 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1572 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1572 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1573 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1573 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1574 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1574 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1575 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1575 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1576 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1576 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1577 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1577 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1578 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1578 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1579 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1579 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1580 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1580 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1581 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1581 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1582 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1582 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1583 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1583 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1584 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1584 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1585 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1585 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1586 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1586 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1587 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1587 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1588 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1588 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1589 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1589 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1590 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1590 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1591 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1591 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1592 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1592 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1593 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1593 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1594 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1594 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1595 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1595 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1596 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1596 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1597 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1597 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1598 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1598 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1599 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1599 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1600 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1600 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1601 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1601 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1602 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1602 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1603 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1603 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1604 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1604 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1605 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1605 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1606 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1606 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1607 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1607 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1608 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1608 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1609 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1609 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1610 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1610 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1611 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1611 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1612 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1612 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1613 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1613 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1614 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1614 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1615 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1615 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1616 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1616 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1617 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1617 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1618 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1618 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1619 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1619 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1620 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1620 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1621 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1621 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1622 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1622 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1623 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1623 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1624 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1624 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1625 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1625 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1626 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1626 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1627 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1627 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1628 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1628 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1629 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1629 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1630 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1630 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1631 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1631 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1632 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1632 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1633 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1633 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1634 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1634 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1635 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1635 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1636 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1636 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1637 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1637 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1638 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1638 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1639 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1639 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1640 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1640 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1641 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1641 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1642 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1642 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1643 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1643 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1644 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1644 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1645 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1645 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1646 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1646 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1647 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1647 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1648 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1648 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1649 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1649 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1650 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1650 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1651 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1651 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1652 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1652 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1653 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1653 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1654 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1654 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1655 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1655 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1656 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1656 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1657 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1657 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1658 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1658 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1659 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1659 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1660 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1660 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1661 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1661 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1662 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1662 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1663 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1663 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1664 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1664 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1665 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1665 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1666 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1666 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1667 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1667 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1668 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1668 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1669 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1669 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1670 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1670 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1671 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1671 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1672 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1672 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1673 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1673 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1674 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1674 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1675 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1675 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1676 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1676 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1677 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1677 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1678 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1678 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1679 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1679 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1680 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1680 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1681 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1681 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1682 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1682 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1683 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1683 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1684 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1684 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1685 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1685 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1686 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1686 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1687 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1687 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1688 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1688 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1689 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1689 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1690 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1690 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1691 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1691 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1692 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1692 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1693 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1693 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1694 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1694 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1695 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1695 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1696 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1696 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1697 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1697 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1698 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1698 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1699 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1699 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1700 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1700 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1701 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1701 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1702 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1702 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1703 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1703 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1704 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1704 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1705 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1705 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1706 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1706 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1707 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1707 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1708 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1708 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1709 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1709 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1710 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1710 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1711 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1711 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1712 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1712 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1713 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1713 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1714 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1714 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1715 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1715 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1716 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1716 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1717 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1717 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1718 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1718 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1719 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1719 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1720 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1720 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1721 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1721 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1722 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1722 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1723 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1723 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1724 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1724 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1725 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1725 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1726 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1726 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1727 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1727 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1728 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1728 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1729 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1729 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1730 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1730 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1731 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1731 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1732 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1732 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1733 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1733 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1734 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1734 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1735 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1735 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1736 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1736 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1737 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1737 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1738 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1738 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1739 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1739 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1740 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1740 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1741 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1741 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1742 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1742 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1743 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1743 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1744 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1744 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1745 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1745 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1746 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1746 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1747 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1747 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1748 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1748 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1749 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1749 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1750 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1750 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1751 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1751 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1752 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1752 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1753 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1753 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1754 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1754 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1755 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1755 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1756 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1756 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1757 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1757 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1758 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1758 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1759 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1759 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1760 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1760 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1761 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1761 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1762 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1762 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1763 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1763 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1764 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1764 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1765 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1765 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1766 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1766 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1767 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1767 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1768 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1768 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1769 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1769 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1770 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1770 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1771 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1771 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1772 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1772 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1773 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1773 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1774 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1774 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1775 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 1775 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1776 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1776 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1777 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1777 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1778 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1778 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1779 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1779 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1780 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1780 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1781 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1781 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1782 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1782 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1783 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1783 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1784 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1784 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1785 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1785 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1786 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1786 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1787 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1787 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1788 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1788 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1789 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1789 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1790 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1790 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1791 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1791 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1792 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1792 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1793 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1793 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1794 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1794 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1795 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1795 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1796 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1796 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1797 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1797 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1798 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1798 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1799 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1799 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1800 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1800 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1801 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1801 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1802 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1802 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1803 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1803 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1804 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1804 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1805 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1805 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1806 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1806 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1807 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1807 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1808 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1808 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1809 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1809 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1810 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1810 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1811 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1811 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1812 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1812 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1813 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1813 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1814 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1814 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1815 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1815 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1816 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1816 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1817 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1817 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1818 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1818 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1819 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1819 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1820 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1820 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1821 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1821 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1822 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1822 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1823 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1823 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1824 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1824 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1825 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1825 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1826 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1826 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1827 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1827 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1828 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1828 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1829 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1829 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1830 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1830 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1831 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1831 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1832 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1832 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1833 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1833 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1834 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1834 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1835 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1835 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1836 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1836 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1837 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1837 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1838 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1838 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1839 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1839 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1840 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1840 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1841 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1841 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1842 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1842 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1843 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1843 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1844 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1844 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1845 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1845 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1846 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1846 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1847 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1847 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1848 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1848 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1849 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1849 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1850 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1850 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1851 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1851 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1852 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1852 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1853 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1853 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1854 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1854 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1855 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1855 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1856 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1856 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1857 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1857 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1858 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1858 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1859 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1859 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1860 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1860 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1861 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1861 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1862 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1862 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1863 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1863 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1864 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1864 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1865 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1865 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1866 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1866 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1867 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1867 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1868 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1868 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1869 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1869 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1870 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1870 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1871 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1871 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1872 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1872 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1873 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1873 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1874 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1874 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1875 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1875 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1876 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1876 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1877 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1877 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1878 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1878 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1879 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1879 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1880 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1880 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1881 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1881 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1882 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1882 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1883 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1883 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1884 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1884 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1885 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1885 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1886 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1886 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1887 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1887 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1888 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1888 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1889 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1889 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1890 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1890 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1891 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1891 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1892 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1892 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1893 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1893 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1894 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1894 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1895 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1895 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1896 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1896 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1897 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1897 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1898 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1898 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1899 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1899 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1900 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1900 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1901 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1901 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1902 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1902 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1903 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1903 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1904 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1904 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1905 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1905 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1906 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1906 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1907 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1907 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1908 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1908 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1909 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1909 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1910 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1910 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1911 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1911 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1912 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1912 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1913 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1913 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1914 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1914 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1915 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1915 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1916 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1916 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1917 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1917 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1918 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1918 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1919 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1919 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1920 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1920 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1921 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1921 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1922 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1922 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1923 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1923 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1924 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1924 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1925 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1925 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1926 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1926 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1927 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1927 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1928 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1928 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1929 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1929 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1930 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1930 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1931 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1931 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1932 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1932 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1933 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1933 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1934 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1934 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1935 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1935 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1936 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1936 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1937 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1937 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1938 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1938 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1939 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1939 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1940 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1940 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1941 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1941 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1942 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1942 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1943 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1943 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1944 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1944 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1945 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1945 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1946 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1946 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1947 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1947 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1948 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1948 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1949 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1949 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1950 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1950 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1951 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1951 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1952 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1952 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1953 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1953 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1954 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1954 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1955 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1955 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1956 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1956 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1957 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1957 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1958 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1958 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1959 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1959 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1960 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1960 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1961 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1961 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1962 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1962 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1963 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1963 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1964 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1964 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1965 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1965 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1966 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1966 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1967 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1967 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1968 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1968 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1969 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1969 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1970 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1970 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1971 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1971 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1972 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1972 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1973 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1973 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1974 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1974 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1975 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1975 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1976 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1976 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1977 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1977 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1978 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1978 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1979 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1979 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1980 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1980 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1981 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1981 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1982 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1982 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1983 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1983 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1984 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1984 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1985 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1985 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1986 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1986 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1987 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1987 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1988 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1988 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1989 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1989 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1990 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1990 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1991 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1991 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1992 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1992 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1993 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1993 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1994 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1994 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1995 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1995 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1996 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1996 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1997 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1997 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1998 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 1998 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1999 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 1999 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2000 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2000 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2001 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2001 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2002 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2002 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2003 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2003 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2004 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2004 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2005 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2005 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2006 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2006 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2007 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2007 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2008 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2008 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2009 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2009 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2010 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2010 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2011 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2011 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2012 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2012 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2013 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2013 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2014 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2014 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2015 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2015 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2016 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2016 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2017 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2017 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2018 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2018 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2019 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2019 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2020 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2020 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2021 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2021 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2022 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2022 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2023 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2023 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2024 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2024 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2025 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2025 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2026 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2026 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2027 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2027 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2028 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2028 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2029 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2029 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2030 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2030 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2031 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2031 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2032 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2032 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2033 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2033 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2034 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2034 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2035 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2035 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2036 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2036 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2037 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2037 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2038 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2038 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2039 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2039 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2040 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2040 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2041 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2041 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2042 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2042 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2043 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2043 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2044 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2044 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2045 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2045 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2046 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2046 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2047 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2047 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2048 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2048 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2049 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2049 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2050 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2050 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2051 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2051 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2052 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2052 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2053 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2053 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2054 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2054 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2055 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2055 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2056 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2056 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2057 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2057 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2058 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2058 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2059 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2059 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2060 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2060 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2061 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2061 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2062 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2062 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2063 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2063 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2064 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2064 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2065 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2065 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2066 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2066 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2067 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2067 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2068 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2068 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2069 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2069 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2070 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2070 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2071 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2071 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2072 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2072 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2073 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2073 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2074 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2074 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2075 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2075 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2076 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2076 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2077 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2077 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2078 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2078 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2079 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2079 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2080 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2080 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2081 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2081 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2082 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2082 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2083 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2083 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2084 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2084 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2085 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2085 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2086 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2086 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2087 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2087 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2088 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2088 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2089 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2089 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2090 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2090 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2091 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2091 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2092 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2092 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2093 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2093 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2094 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2094 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2095 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2095 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2096 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2096 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2097 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2097 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2098 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2098 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2099 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2099 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2100 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2100 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2101 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2101 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2102 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2102 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2103 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2103 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2104 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2104 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2105 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2105 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2106 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2106 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2107 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2107 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2108 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2108 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2109 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2109 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2110 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2110 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2111 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2111 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2112 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2112 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2113 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2113 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2114 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2114 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2115 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2115 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2116 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2116 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2117 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2117 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2118 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2118 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2119 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2119 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2120 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2120 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2121 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2121 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2122 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2122 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2123 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2123 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2124 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2124 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2125 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2125 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2126 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2126 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2127 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2127 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2128 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2128 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2129 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2129 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2130 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2130 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2131 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2131 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2132 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2132 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2133 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2133 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2134 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2134 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2135 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2135 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2136 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2136 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2137 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2137 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2138 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2138 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2139 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2139 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2140 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2140 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2141 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2141 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2142 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2142 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2143 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2143 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2144 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2144 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2145 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2145 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2146 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2146 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2147 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2147 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2148 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2148 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2149 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2149 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2150 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2150 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2151 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2151 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2152 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2152 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2153 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2153 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2154 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2154 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2155 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2155 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2156 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2156 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2157 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2157 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2158 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2158 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2159 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2159 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2160 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2160 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2161 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2161 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2162 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2162 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2163 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2163 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2164 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2164 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2165 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2165 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2166 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2166 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2167 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2167 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2168 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2168 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2169 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2169 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2170 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2170 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2171 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2171 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2172 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2172 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2173 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2173 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2174 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2174 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2175 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2175 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2176 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2176 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2177 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2177 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2178 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2178 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2179 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2179 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2180 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2180 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2181 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2181 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2182 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2182 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2183 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2183 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2184 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2184 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2185 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2185 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2186 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2186 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2187 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2187 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2188 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2188 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2189 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2189 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2190 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2190 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2191 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2191 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2192 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2192 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2193 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2193 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2194 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2194 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2195 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2195 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2196 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2196 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2197 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2197 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2198 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2198 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2199 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2199 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2200 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2200 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2201 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2201 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2202 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2202 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2203 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2203 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2204 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2204 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2205 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2205 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2206 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2206 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2207 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2207 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2208 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2208 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2209 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2209 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2210 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2210 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2211 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2211 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2212 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2212 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2213 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2213 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2214 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2214 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2215 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2215 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2216 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2216 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2217 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2217 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2218 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2218 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2219 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2219 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2220 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2220 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2221 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2221 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2222 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2222 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2223 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2223 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2224 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2224 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2225 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2225 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2226 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2226 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2227 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2227 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2228 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2228 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2229 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2229 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2230 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2230 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2231 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2231 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2232 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2232 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2233 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2233 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2234 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2234 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2235 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2235 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2236 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2236 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2237 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2237 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2238 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2238 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2239 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2239 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2240 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2240 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2241 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2241 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2242 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2242 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2243 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2243 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2244 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2244 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2245 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2245 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2246 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2246 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2247 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2247 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2248 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2248 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2249 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2249 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2250 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2250 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2251 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2251 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2252 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2252 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2253 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2253 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2254 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2254 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2255 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2255 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2256 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2256 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2257 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2257 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2258 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2258 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2259 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2259 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2260 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2260 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2261 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2261 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2262 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2262 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2263 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2263 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2264 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2264 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2265 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2265 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2266 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2266 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2267 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2267 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2268 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2268 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2269 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2269 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2270 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2270 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2271 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2271 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2272 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2272 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2273 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2273 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2274 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2274 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2275 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2275 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2276 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2276 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2277 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2277 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2278 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2278 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2279 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2279 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2280 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2280 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2281 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2281 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2282 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2282 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2283 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2283 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2284 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2284 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2285 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2285 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2286 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2286 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2287 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2287 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2288 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2288 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2289 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2289 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2290 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2290 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2291 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2291 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2292 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2292 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2293 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2293 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2294 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2294 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2295 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2295 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2296 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2296 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2297 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2297 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2298 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2298 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2299 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2299 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2300 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2300 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2301 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2301 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2302 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2302 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2303 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2303 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2304 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2304 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2305 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2305 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2306 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2306 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2307 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2307 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2308 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2308 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2309 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2309 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2310 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2310 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2311 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2311 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2312 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2312 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2313 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2313 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2314 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2314 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2315 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2315 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2316 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2316 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2317 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2317 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2318 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2318 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2319 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2319 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2320 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2320 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2321 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2321 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2322 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2322 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2323 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2323 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2324 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2324 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2325 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2325 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2326 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2326 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2327 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2327 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2328 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2328 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2329 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2329 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2330 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2330 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2331 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2331 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2332 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2332 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2333 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2333 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2334 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2334 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2335 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2335 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2336 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2336 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2337 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2337 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2338 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2338 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2339 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2339 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2340 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2340 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2341 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2341 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2342 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2342 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2343 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2343 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2344 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2344 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2345 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2345 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2346 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2346 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2347 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2347 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2348 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2348 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2349 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2349 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2350 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2350 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2351 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2351 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2352 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2352 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2353 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2353 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2354 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2354 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2355 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2355 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2356 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2356 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2357 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2357 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2358 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2358 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2359 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2359 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2360 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2360 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2361 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2361 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2362 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2362 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2363 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2363 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2364 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2364 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2365 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2365 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2366 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2366 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2367 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2367 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2368 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2368 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2369 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2369 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2370 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2370 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2371 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2371 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2372 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2372 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2373 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2373 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2374 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2374 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2375 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2375 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2376 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2376 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2377 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2377 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2378 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2378 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2379 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2379 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2380 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2380 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2381 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2381 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2382 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2382 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2383 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2383 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2384 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2384 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2385 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2385 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2386 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2386 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2387 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2387 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2388 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2388 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2389 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2389 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2390 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2390 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2391 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2391 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2392 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2392 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2393 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2393 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2394 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2394 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2395 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2395 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2396 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2396 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2397 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2397 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2398 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2398 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2399 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2399 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2400 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2400 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2401 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2401 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2402 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2402 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2403 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2403 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2404 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2404 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2405 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2405 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2406 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2406 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2407 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2407 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2408 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2408 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2409 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2409 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2410 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2410 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2411 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2411 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2412 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2412 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2413 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2413 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2414 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2414 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2415 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2415 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2416 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2416 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2417 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2417 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2418 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2418 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2419 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2419 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2420 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2420 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2421 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2421 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2422 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2422 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2423 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2423 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2424 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2424 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2425 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2425 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2426 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2426 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2427 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2427 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2428 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2428 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2429 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2429 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2430 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2430 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2431 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2431 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2432 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2432 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2433 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2433 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2434 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2434 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2435 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2435 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2436 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2436 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2437 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2437 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2438 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2438 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2439 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2439 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2440 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2440 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2441 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2441 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2442 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2442 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2443 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2443 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2444 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2444 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2445 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2445 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2446 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2446 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2447 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2447 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2448 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2448 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2449 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2449 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2450 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2450 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2451 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2451 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2452 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2452 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2453 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2453 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2454 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2454 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2455 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2455 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2456 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2456 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2457 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2457 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2458 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2458 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2459 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2459 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2460 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2460 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2461 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2461 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2462 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2462 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2463 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2463 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2464 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2464 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2465 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2465 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2466 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2466 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2467 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2467 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2468 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2468 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2469 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2469 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2470 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2470 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2471 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2471 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2472 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2472 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2473 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2473 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2474 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2474 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2475 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2475 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2476 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2476 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2477 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2477 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2478 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2478 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2479 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2479 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2480 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2480 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2481 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2481 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2482 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2482 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2483 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2483 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2484 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2484 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2485 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2485 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2486 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2486 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2487 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2487 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2488 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2488 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2489 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2489 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2490 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2490 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2491 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2491 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2492 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2492 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2493 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2493 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2494 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2494 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2495 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2495 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2496 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2496 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2497 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2497 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2498 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2498 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2499 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2499 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2500 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2500 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2501 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2501 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2502 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2502 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2503 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2503 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2504 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2504 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2505 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2505 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2506 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2506 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2507 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2507 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2508 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2508 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2509 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2509 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2510 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2510 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2511 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2511 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2512 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2512 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2513 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2513 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2514 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2514 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2515 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2515 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2516 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2516 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2517 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2517 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2518 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2518 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2519 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2519 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2520 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2520 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2521 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2521 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2522 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2522 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2523 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2523 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2524 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2524 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2525 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2525 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2526 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2526 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2527 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2527 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2528 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2528 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2529 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2529 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2530 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2530 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2531 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2531 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2532 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2532 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2533 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2533 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2534 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2534 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2535 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2535 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2536 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2536 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2537 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2537 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2538 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2538 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2539 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2539 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2540 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2540 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2541 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2541 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2542 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2542 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2543 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2543 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2544 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2544 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2545 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2545 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2546 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2546 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2547 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2547 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2548 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2548 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2549 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2549 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2550 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2550 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2551 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2551 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2552 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2552 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2553 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2553 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2554 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2554 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2555 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2555 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2556 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2556 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2557 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2557 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2558 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2558 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2559 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2559 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2560 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2560 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2561 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2561 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2562 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2562 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2563 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2563 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2564 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2564 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2565 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2565 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2566 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2566 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2567 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2567 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2568 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2568 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2569 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2569 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2570 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2570 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2571 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2571 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2572 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2572 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2573 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2573 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2574 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2574 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2575 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2575 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2576 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2576 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2577 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2577 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2578 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2578 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2579 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2579 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2580 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2580 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2581 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2581 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2582 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2582 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2583 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2583 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2584 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2584 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2585 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2585 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2586 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2586 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2587 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2587 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2588 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2588 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2589 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2589 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2590 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2590 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2591 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2591 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2592 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2592 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2593 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2593 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2594 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2594 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2595 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2595 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2596 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2596 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2597 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2597 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2598 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2598 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2599 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2599 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2600 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2600 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2601 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2601 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2602 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2602 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2603 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2603 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2604 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2604 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2605 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2605 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2606 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2606 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2607 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2607 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2608 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2608 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2609 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2609 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2610 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2610 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2611 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2611 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2612 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2612 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2613 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2613 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2614 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2614 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2615 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2615 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2616 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2616 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2617 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2617 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2618 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2618 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2619 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2619 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2620 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2620 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2621 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2621 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2622 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2622 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2623 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2623 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2624 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2624 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2625 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2625 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2626 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2626 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2627 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2627 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2628 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2628 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2629 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2629 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2630 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2630 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2631 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2631 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2632 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2632 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2633 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2633 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2634 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2634 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2635 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2635 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2636 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2636 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2637 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2637 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2638 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2638 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2639 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <220> <223> C-term amidated <400> 2639 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2640 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-term acetylated <400> 2640 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2641 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2641 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2642 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2642 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2643 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2643 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2644 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2644 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2645 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2645 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2646 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2646 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2647 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2647 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2648 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2648 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2649 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2649 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2650 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2650 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2651 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2651 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2652 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2652 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2653 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2653 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2654 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2654 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2655 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2655 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2656 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2656 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2657 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2657 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2658 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2658 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2659 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2659 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2660 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2660 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2661 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2661 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2662 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2662 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2663 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2663 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2664 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2664 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2665 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2665 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2666 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2666 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2667 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2667 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2668 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2668 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2669 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2669 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2670 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2670 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2671 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2671 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2672 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2672 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2673 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2673 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2674 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2674 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2675 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2675 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2676 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2676 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2677 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2677 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2678 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2678 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2679 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2679 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2680 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2680 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2681 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2681 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2682 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2682 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2683 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2683 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2684 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2684 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2685 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2685 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2686 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2686 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2687 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2687 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2688 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2688 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2689 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2689 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2690 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2690 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2691 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2691 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2692 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2692 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2693 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2693 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2694 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2694 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2695 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2695 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2696 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2696 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2697 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2697 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2698 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2698 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2699 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2699 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2700 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2700 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2701 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2701 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2702 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2702 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2703 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2703 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2704 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2704 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2705 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2705 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2706 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2706 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2707 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2707 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2708 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2708 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2709 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2709 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2710 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2710 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2711 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2711 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2712 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2712 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2713 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2713 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2714 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2714 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2715 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2715 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2716 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2716 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2717 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2717 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2718 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2718 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2719 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2719 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2720 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2720 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2721 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2721 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2722 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2722 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2723 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2723 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2724 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2724 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2725 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2725 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2726 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2726 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2727 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2727 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2728 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2728 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2729 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2729 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2730 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2730 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2731 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2731 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2732 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2732 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2733 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2733 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2734 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2734 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2735 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2735 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2736 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2736 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2737 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2737 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2738 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2738 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2739 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2739 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2740 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2740 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2741 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2741 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2742 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2742 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2743 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2743 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2744 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2744 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2745 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2745 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2746 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2746 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2747 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2747 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2748 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2748 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2749 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2749 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2750 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2750 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2751 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2751 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2752 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2752 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2753 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2753 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2754 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2754 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2755 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2755 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2756 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2756 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2757 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2757 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2758 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2758 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2759 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2759 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2760 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2760 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2761 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2761 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2762 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2762 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2763 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2763 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2764 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2764 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2765 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2765 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2766 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2766 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2767 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2767 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2768 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2768 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2769 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2769 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2770 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2770 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2771 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2771 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2772 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2772 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2773 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2773 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2774 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2774 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2775 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2775 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2776 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2776 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2777 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2777 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2778 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2778 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2779 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2779 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2780 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2780 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2781 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2781 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2782 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2782 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2783 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2783 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2784 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2784 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2785 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2785 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2786 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2786 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2787 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2787 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2788 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2788 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2789 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2789 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2790 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2790 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2791 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2791 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2792 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2792 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2793 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2793 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2794 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2794 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2795 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2795 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2796 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2796 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2797 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2797 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2798 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2798 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2799 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2799 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2800 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2800 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2801 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2801 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2802 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2802 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2803 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2803 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2804 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2804 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2805 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2805 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2806 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2806 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2807 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2807 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2808 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2808 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2809 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2809 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2810 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2810 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2811 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2811 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2812 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2812 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2813 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2813 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2814 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2814 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2815 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2815 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2816 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2816 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2817 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2817 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2818 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2818 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2819 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2819 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2820 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2820 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2821 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2821 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2822 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2822 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2823 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2823 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2824 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2824 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2825 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2825 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2826 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2826 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2827 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2827 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2828 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2828 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2829 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2829 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2830 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2830 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2831 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2831 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2832 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2832 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2833 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2833 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2834 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2834 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2835 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2835 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2836 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2836 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2837 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2837 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2838 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2838 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2839 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2839 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2840 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2840 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2841 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2841 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2842 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2842 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2843 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2843 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2844 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2844 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2845 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2845 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2846 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2846 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2847 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2847 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2848 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2848 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2849 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2849 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2850 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2850 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2851 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2851 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2852 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2852 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2853 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2853 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2854 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2854 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2855 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2855 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2856 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2856 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2857 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2857 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2858 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2858 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2859 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2859 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2860 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2860 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2861 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2861 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2862 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2862 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2863 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2863 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2864 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2864 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2865 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2865 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2866 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2866 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2867 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2867 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2868 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2868 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2869 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2869 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2870 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2870 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2871 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2871 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2872 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2872 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2873 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2873 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2874 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2874 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2875 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2875 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2876 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2876 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2877 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2877 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2878 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2878 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2879 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2879 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2880 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2880 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2881 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2881 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2882 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2882 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2883 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2883 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2884 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2884 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2885 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2885 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2886 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2886 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2887 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2887 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2888 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2888 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2889 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2889 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2890 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2890 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2891 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2891 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2892 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2892 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2893 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2893 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2894 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2894 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2895 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2895 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2896 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2896 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2897 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2897 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2898 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2898 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2899 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2899 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2900 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2900 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2901 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2901 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2902 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2902 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2903 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2903 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2904 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2904 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2905 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2905 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2906 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2906 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2907 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2907 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2908 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2908 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2909 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2909 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2910 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2910 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2911 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2911 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2912 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2912 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2913 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2913 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2914 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2914 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2915 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2915 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2916 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2916 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2917 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2917 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2918 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2918 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2919 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2919 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2920 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2920 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2921 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2921 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2922 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2922 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2923 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2923 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2924 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2924 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2925 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2925 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2926 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2926 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2927 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2927 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2928 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2928 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2929 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2929 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2930 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2930 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2931 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2931 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2932 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2932 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2933 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2933 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2934 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2934 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2935 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2935 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2936 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2936 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2937 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2937 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2938 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2938 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2939 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2939 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2940 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2940 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2941 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2941 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2942 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2942 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2943 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2943 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2944 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2944 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2945 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2945 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2946 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2946 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2947 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2947 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2948 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2948 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2949 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2949 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2950 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2950 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2951 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2951 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2952 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2952 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2953 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2953 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2954 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2954 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2955 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2955 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2956 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2956 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2957 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2957 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2958 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2958 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2959 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2959 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2960 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2960 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2961 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2961 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2962 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2962 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2963 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2963 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2964 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2964 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2965 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2965 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2966 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2966 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2967 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2967 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2968 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2968 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2969 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2969 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2970 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2970 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2971 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2971 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2972 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2972 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2973 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2973 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2974 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2974 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2975 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2975 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2976 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2976 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2977 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2977 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2978 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2978 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2979 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2979 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2980 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2980 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2981 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2981 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2982 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2982 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2983 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2983 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2984 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2984 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2985 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2985 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2986 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2986 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2987 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2987 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2988 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2988 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2989 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2989 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2990 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2990 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2991 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2991 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2992 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2992 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2993 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2993 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2994 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2994 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2995 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2995 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2996 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2996 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2997 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2997 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2998 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2998 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2999 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 2999 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3000 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3000 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3001 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3001 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3002 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3002 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3003 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3003 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3004 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3004 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3005 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3005 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3006 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3006 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3007 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3007 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3008 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3008 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3009 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3009 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3010 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3010 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3011 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3011 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3012 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3012 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3013 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3013 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3014 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3014 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3015 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3015 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3016 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3016 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3017 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3017 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3018 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3018 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3019 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3019 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3020 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3020 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3021 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3021 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3022 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3022 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3023 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3023 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3024 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3024 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3025 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3025 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3026 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3026 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3027 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3027 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3028 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3028 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3029 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3029 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3030 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3030 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3031 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3031 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3032 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3032 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3033 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3033 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3034 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3034 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3035 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3035 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3036 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3036 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3037 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3037 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3038 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3038 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3039 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3039 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3040 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3040 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3041 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3041 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3042 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3042 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3043 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3043 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3044 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3044 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3045 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3045 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3046 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3046 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3047 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3047 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3048 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3048 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3049 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3049 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3050 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3050 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3051 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3051 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3052 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3052 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3053 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3053 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3054 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3054 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3055 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3055 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3056 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3056 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3057 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3057 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3058 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3058 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3059 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3059 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3060 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3060 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3061 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3061 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3062 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3062 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3063 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3063 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3064 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3064 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3065 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3065 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3066 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3066 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3067 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3067 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3068 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3068 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3069 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3069 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3070 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3070 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3071 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3071 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3072 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3072 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3073 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3073 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3074 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3074 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3075 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3075 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3076 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3076 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3077 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3077 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3078 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3078 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3079 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3079 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3080 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3080 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3081 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3081 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3082 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3082 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3083 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3083 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3084 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3084 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3085 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3085 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3086 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3086 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3087 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3087 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3088 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3088 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3089 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3089 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3090 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3090 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3091 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3091 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3092 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3092 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3093 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3093 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3094 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3094 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3095 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3095 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3096 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3096 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3097 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3097 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3098 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3098 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3099 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3099 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3100 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3100 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3101 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3101 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3102 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3102 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3103 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3103 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3104 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3104 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3105 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3105 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3106 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3106 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3107 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3107 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3108 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3108 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3109 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3109 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3110 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3110 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3111 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3111 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3112 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3112 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3113 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3113 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3114 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3114 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3115 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3115 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3116 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3116 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3117 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3117 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3118 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3118 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3119 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3119 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3120 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3120 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3121 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3121 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3122 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3122 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3123 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3123 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3124 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3124 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3125 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3125 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3126 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3126 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3127 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3127 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3128 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3128 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3129 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3129 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3130 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3130 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3131 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3131 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3132 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3132 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3133 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3133 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3134 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3134 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3135 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3135 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3136 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3136 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3137 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3137 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3138 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3138 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3139 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3139 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3140 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3140 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3141 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3141 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3142 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3142 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3143 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3143 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3144 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3144 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3145 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3145 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3146 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3146 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3147 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3147 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3148 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3148 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3149 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3149 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3150 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3150 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3151 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3151 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3152 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3152 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3153 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3153 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3154 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3154 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3155 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3155 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3156 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3156 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3157 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3157 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3158 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3158 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3159 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3159 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3160 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3160 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3161 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3161 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3162 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3162 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3163 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3163 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3164 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3164 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3165 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3165 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3166 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3166 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3167 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3167 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3168 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3168 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3169 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3169 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3170 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3170 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3171 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3171 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3172 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3172 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3173 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3173 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3174 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3174 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3175 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3175 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3176 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3176 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3177 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3177 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3178 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3178 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3179 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3179 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3180 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3180 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3181 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3181 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3182 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3182 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3183 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3183 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3184 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3184 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3185 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3185 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3186 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3186 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3187 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3187 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3188 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3188 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3189 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3189 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3190 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3190 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3191 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3191 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3192 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3192 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3193 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3193 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3194 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3194 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3195 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3195 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3196 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3196 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3197 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3197 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3198 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3198 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3199 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3199 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3200 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3200 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3201 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3201 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3202 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3202 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3203 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3203 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3204 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3204 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3205 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3205 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3206 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3206 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3207 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3207 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3208 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3208 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3209 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3209 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3210 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3210 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3211 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3211 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3212 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3212 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3213 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3213 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3214 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3214 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3215 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3215 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3216 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3216 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3217 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3217 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3218 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3218 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3219 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3219 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3220 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3220 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3221 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3221 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3222 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3222 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3223 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3223 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3224 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3224 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3225 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3225 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3226 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3226 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3227 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3227 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3228 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3228 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3229 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3229 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3230 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3230 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3231 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3231 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3232 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3232 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3233 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3233 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3234 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3234 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3235 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3235 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3236 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3236 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3237 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3237 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3238 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3238 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3239 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3239 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3240 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3240 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3241 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3241 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3242 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3242 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3243 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3243 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3244 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3244 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3245 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3245 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3246 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3246 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3247 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3247 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3248 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3248 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3249 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3249 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3250 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3250 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3251 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3251 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3252 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3252 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3253 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3253 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3254 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3254 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3255 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3255 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3256 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3256 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3257 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3257 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3258 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3258 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3259 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3259 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3260 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3260 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3261 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3261 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3262 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3262 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3263 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3263 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3264 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3264 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3265 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3265 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3266 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3266 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3267 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3267 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3268 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3268 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3269 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3269 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3270 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3270 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3271 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3271 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3272 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3272 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3273 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3273 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3274 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3274 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3275 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3275 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3276 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3276 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3277 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3277 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3278 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3278 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3279 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3279 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3280 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3280 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3281 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3281 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3282 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3282 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3283 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3283 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3284 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3284 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3285 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3285 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3286 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3286 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3287 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3287 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3288 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3288 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3289 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3289 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3290 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3290 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3291 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3291 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3292 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3292 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3293 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3293 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3294 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3294 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3295 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3295 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3296 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3296 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3297 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3297 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3298 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3298 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3299 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3299 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3300 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3300 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3301 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3301 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3302 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3302 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3303 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3303 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3304 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3304 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3305 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3305 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3306 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3306 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3307 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3307 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3308 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3308 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3309 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3309 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3310 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3310 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3311 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3311 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3312 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3312 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3313 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3313 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3314 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3314 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3315 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3315 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3316 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3316 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3317 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3317 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3318 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3318 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3319 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3319 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3320 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3320 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3321 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3321 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3322 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3322 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3323 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3323 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3324 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3324 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3325 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3325 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3326 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3326 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3327 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3327 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3328 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3328 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3329 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3329 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3330 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3330 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3331 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3331 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3332 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3332 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3333 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3333 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3334 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3334 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3335 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3335 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3336 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3336 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3337 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3337 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3338 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3338 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3339 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3339 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3340 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3340 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3341 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3341 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3342 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3342 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3343 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3343 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3344 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3344 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3345 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3345 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3346 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3346 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3347 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3347 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3348 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3348 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3349 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3349 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3350 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3350 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3351 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3351 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3352 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3352 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3353 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3353 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3354 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3354 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3355 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3355 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3356 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3356 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3357 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3357 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3358 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3358 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3359 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3359 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3360 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3360 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3361 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3361 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3362 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3362 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3363 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3363 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3364 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3364 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3365 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3365 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3366 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3366 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3367 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3367 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3368 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3368 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3369 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3369 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3370 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3370 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3371 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3371 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3372 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3372 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3373 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3373 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3374 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3374 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3375 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3375 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3376 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3376 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3377 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3377 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3378 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3378 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3379 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3379 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3380 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3380 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3381 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3381 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3382 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3382 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3383 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3383 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3384 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3384 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3385 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3385 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3386 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3386 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3387 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3387 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3388 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3388 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3389 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3389 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3390 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3390 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3391 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3391 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3392 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3392 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3393 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3393 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3394 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3394 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3395 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3395 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3396 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3396 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3397 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3397 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3398 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3398 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3399 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3399 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3400 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3400 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3401 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3401 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3402 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3402 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3403 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3403 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3404 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3404 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3405 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3405 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3406 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3406 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3407 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3407 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3408 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3408 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3409 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3409 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3410 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3410 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3411 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3411 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3412 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3412 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3413 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3413 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3414 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3414 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3415 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3415 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3416 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3416 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3417 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3417 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3418 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3418 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3419 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3419 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3420 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3420 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3421 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3421 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3422 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3422 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3423 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3423 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3424 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3424 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3425 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3425 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3426 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3426 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3427 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3427 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3428 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3428 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3429 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3429 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3430 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3430 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3431 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3431 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3432 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3432 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3433 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3433 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3434 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3434 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3435 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3435 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3436 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3436 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3437 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3437 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3438 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3438 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3439 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3439 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3440 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3440 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3441 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3441 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3442 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3442 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3443 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3443 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3444 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3444 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3445 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3445 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3446 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3446 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3447 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3447 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3448 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3448 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3449 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3449 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3450 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3450 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3451 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3451 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3452 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3452 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3453 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3453 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3454 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3454 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3455 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3455 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3456 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3456 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3457 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3457 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3458 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3458 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3459 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3459 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3460 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3460 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3461 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3461 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3462 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3462 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3463 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3463 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3464 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3464 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3465 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3465 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3466 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3466 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3467 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3467 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3468 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3468 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3469 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3469 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3470 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3470 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3471 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3471 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3472 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3472 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3473 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3473 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3474 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3474 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3475 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3475 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3476 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3476 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3477 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3477 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3478 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3478 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3479 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3479 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3480 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3480 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3481 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3481 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3482 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3482 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3483 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3483 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3484 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3484 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3485 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3485 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3486 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3486 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3487 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3487 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3488 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3488 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3489 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3489 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3490 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3490 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3491 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3491 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3492 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3492 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3493 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3493 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3494 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3494 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3495 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3495 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3496 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3496 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3497 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3497 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3498 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3498 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3499 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3499 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3500 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3500 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3501 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3501 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3502 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3502 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3503 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-term amidated <400> 3503 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3504 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3504 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3505 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3505 Cys Thr Val Ala Leu Pro Gly Gly Tyr Arg Val Arg Val Cys 1 5 10 <210> 3506 <211> 12 <212> PRT <213> Pseudomonas aeruginosa <400> 3506 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 1 5 10 <210> 3507 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3507 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Thr Pro Gly Cys 20 25 <210> 3508 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3508 Leu Ser Thr Ala Ala Asp Cys Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3509 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3509 Leu Ser Thr Ala Ala Cys Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3510 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3510 Leu Ser Thr Ala Cys Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3511 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3511 Leu Ser Thr Ala Ala Thr Met Gln Cys Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3512 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3512 Leu Ser Thr Ala Ala Thr Met Gln Gly Cys Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3513 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3513 Leu Ser Thr Ala Ala Asn Thr Gln Gly Cys Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3514 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3514 Leu Ser Thr Ala Ala Asn Thr Gln Gly Val Cys Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3515 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3515 Leu Ser Thr Ala Ala Asp Met Thr Ala Val Cys Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3516 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3516 Leu Ser Thr Ala Ala Asp Met Thr Ala Val Val Cys Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3517 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3517 Leu Ser Thr Ala Ala Asp Met Gln Thr Val Val Cys Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3518 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3518 Leu Ser Thr Ala Ala Asp Met Gln Thr Val Val Thr Cys Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3519 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3519 Leu Ser Thr Ala Ala Asp Met Gln Ala Thr Val Thr Cys Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3520 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3520 Leu Ser Thr Ala Ala Asp Met Gln Ala Thr Val Thr Asp Cys Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3521 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3521 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Thr Ala Asp Cys Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3522 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3522 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Thr Ala Asp Gly Cys Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3523 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3523 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asn Gly Cys Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3524 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3524 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Ala Thr Met Gly 1 5 10 15 Ser Gly Leu Cys Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3525 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3525 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Leu Thr Ala 1 5 10 15 Ser Gly Leu Cys Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 3526 <211> 18 <212> PRT <213> Pseudomonas aeruginosa <400> 3526 Val Thr Asp Gly Met Ala Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro 1 5 10 15 Asp Asp <210> 3527 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3527 Arg Arg Arg Arg Arg Arg Arg Arg 1 5 <210> 3528 <211> 6 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3528 Val Ser Pro Pro Ala Arg 1 5 <210> 3529 <211> 6 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3529 Tyr Thr Pro Pro Ala Leu 1 5 <210> 3530 <211> 6 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3530 Phe Ser Phe Phe Ala Glu 1 5 <210> 3531 <211> 6 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3531 Ser Gly Leu Asp Lys Asp 1 5

Claims (63)

  1. 단리된 펩타이드로서,
    상기 단리된 펩타이드는 큐프레독신 또는 변형된 잔기를 갖는 큐프레독신 절단(truncation)을 포함하며, 상기 단리된 펩타이드는 야생형 큐프레독신의 약학적 활성 중 하나 이상을 갖는 것을 특징으로 하는 단리된 펩타이드.
  2. 제 1 항에 있어서,
    상기 야생형 큐프레독신의 약학적 활성은 (1) 포유류의 암세포에 진입하는 활성, (2) 비-암성 포유류 세포에는 진입하지 않는 활성, (3) 전암성 포유류 세포에 진입하는 활성, (4) 포유류의 암세포를 죽이는 활성, (5) 전암성 포유류 세포를 죽이는 활성, (6) 포유류의 암세포의 성장을 억제하는 활성, (7) HIV-1 감염을 억제하는 활성, (8) 말라리아에 감염된 적혈구의 기생충혈증을 억제하는 활성, (9) 에프린 신호전달계를 교란하는 활성, (10) 혈관생성을 억제하는 활성으로 구성되는 군으로부터 하나 이상 선택되는 것을 특징으로 하는 단리된 펩타이드.
  3. 제 1 항에 있어서,
    상기 단리된 펩타이드는 야생형 큐프레독신에 비해 개선된 약물 동력학 성질을 하나 이상 갖는 것을 특징으로 하는 단리된 펩타이드.
  4. 제 1 항에 있어서,
    상기 변형된 잔기는 고리화된 잔기를 하나 초과하여 포함하는 것을 특징으로 하는 단리된 펩타이드.
  5. 제 4 항에 있어서,
    상기 잔기는 효소 고리화 반응에 의해 고리화되는 것을 특징으로 하는 단리된 펩타이드.
  6. 제 4 항에 있어서,
    상기 고리화된 잔기는 티오에테르를 포함하는 것을 특징으로 하는 단리된 펩타이드.
  7. 제 4 항에 있어서,
    상기 고리화된 잔기는 락탐 브릿지(bridge)를 포함하는 것을 특징으로 하는 단리된 펩타이드.
  8. 제 6 항에 있어서,
    상기 티오에테르는 시스테인 잔기를 디히드로알라닌 및 디히드로부트린 잔기에 첨가함으로써 형성되는 것을 특징으로 하는 단리된 펩타이드.
  9. 제 8 항에 있어서,
    상기 디히드로알라닌 및 디히드로부트린 잔기는 각각 세린 및 트레오닌의 탈수로부터 유래되는 것을 특징으로 하는 단리된 펩타이드.
  10. 제 3 항에 있어서,
    상기 개선된 약학적 성질은 (1) 환자가 생체 내 변화에 덜 영향받는 성질, (2) 환자의 신체로부터 외부로 느린 속도로 배출되는 성질, (3) 삼차 구조의 증가된 안정성 그리고 (4) 더 길어진 혈장 반감기로 구성되는 군으로부터 하나 이상 선택되는 것을 특징으로 하는 단리된 펩타이드.
  11. 제 1 항에 있어서,
    상기 큐프레독신은 녹농균(Pseudomonas aeruginosa), 포르미디움 라미노섬(Phormidium laminosum ), 울바 페르투시스( Ulva pertussis), 티오바실러스 페로옥시단스(Thiobacillus ferrooxidans), 아크로모박터 시클로클라스테스(Achromobacter cycloclastes), 슈도모나스 시린게(Pseudomonas syringae), 수막구균(Neisseria meningitidis), 장염비브리오균(Vibrio parahaemolyticus), 보데텔라 브론키셉티카(Bordetella bronchiseptica), 보르데텔라 백일해균(Bordetella pertussis), 클로로플렉서스 오란티아쿠스(Chloroflexus aurantiacus) 및 임균(Neisseria gonorrhoeae)로 구성되는 군으로부터 선택되는 유기체로부터 유래된 것인 것을 특징으로 하는 단리된 펩타이드.
  12. 제 1 항에 있어서,
    상기 큐프레독신은 아주린, 플라스토시아닌, 루스티시아닌, 슈도아주린, 오라시아닌(auracyanin), 스텔라시아닌, 오이 기본 단백질 및 아주린-유사 단백질로 구성되는 군으로부터 선택되는 것을 특징으로 하는 단리된 펩타이드.
  13. 제 1 항에 있어서,
    상기 큐프레독신은 서열번호:1 내지 서열번호:12로 구성되는 군으로부터 선택되는 것을 특징으로 하는 단리된 펩타이드.
  14. 제 1 항에 있어서,
    상기 아미노산 서열을 서열번호:13 내지 서열번호:47로 구성되는 군으로부터 선택되는 것을 특징으로 하는 단리된 펩타이드.
  15. 제 1 항에 있어서,
    상기 단리된 펩타이드는 서열번호:1 내지 서열번호:12로 구성되는 군으로부터 선택되는 서열에 대하여 90 %이상의 동일성을 갖는 것을 특징으로 하는 단리된 펩타이드.
  16. 제 1 항에 있어서,
    상기 단리된 펩타이드는 가수분해에 덜 영향받는 것을 특징으로 하는 단리된 펩타이드.
  17. 제 1 항에 있어서,
    상기 변형된 잔기는, 아스파라긴 또는 세린 이외의 아미노산 잔기로 치환되는 큐프레독신에, 하나 이상의 아스파라긴 또는 세린 잔기를 포함하는 것을 특징으로 하는 단리된 펩타이드.
  18. 제 17 항에 있어서,
    상기 아스파라긴 또는 세린 잔기는 글루탐산 또는 트레오닌 잔기로 치환되는 것을 특징으로 하는 단리된 펩타이드.
  19. 제 1 항에 있어서,
    상기 단리된 펩타이드는 탈아미노화 반응에 덜 영향받는 것을 특징으로 하는 단리된 펩타이드.
  20. 제 1 항에 있어서,
    상기 변형된 잔기는, 글리신 이외의 아미노산 잔기로 치환되는 큐프레독신 유래 펩타이드에, 하나 이상의 글리신 잔기를 포함하는 것을 특징으로 하는 단리된 펩타이드.
  21. 제 20 항에 있어서,
    하나 이상의 글리신 잔기는 트레오닌 또는 알라닌 잔기로 치환되는 것을 특징으로 하는 단리된 펩타이드.
  22. 제 21 항에 있어서,
    녹농균 아주린(서열번호:1)의 58번 또는 63번 잔기에 상응하는, 상기 큐프레독신 유래 펩타이드 중의 하나 이상의 글리신 잔기는, 치환되는 것을 특징으로 하는 단리된 펩타이드
  23. 제 1 항에 있어서,
    상기 단리된 펩타이드는 산화반응에 덜 영향받는 것을 특징으로 하는 단리된 펩타이드.
  24. 제 1 항에 있어서,
    상기 변형된 잔기는, 다른 아미노산 잔기로 치환되는 상기 큐프레독신 유래 펩타이드에, 하나 이상의 메티오닌 또는 시스테인 잔기를 포함하는 것을 특징으로 하는 단리된 펩타이드.
  25. 제 1 항에 있어서,
    상기 단리된 펩타이드는 디케토피페라진 및 피로글루탐산 형성에 덜 영향받는 것을 특징으로 하는 단리된 펩타이드.
  26. 제 1 항에 있어서,
    상기 변형된 잔기는, 글리신 이외의 아미노산 잔기로 치환되는 큐프레독신의 N-말단으로부터 1번, 2번 또는 3번 위치에, 글리신 잔기를 포함하는 것을 특징으로 하는 단리된 펩타이드.
  27. 제 1 항에 있어서,
    상기 변형된 잔기는, 프롤린을 제외한 아미노산 잔기로 치환되는 큐프레독신의 N-말단으로부터 3번째 위치에, 프롤린 잔기를 포함하는 것을 특징으로 하는 단리된 펩타이드.
  28. 제 1 항에 있어서,
    상기 변형된 잔기는, 아스파라긴을 제외한 아미노산 잔기로 치환되는 큐프레독신의 N-말단에, 아스파라긴 잔기를 포함하는 것을 특징으로 하는 단리된 펩타이드.
  29. 제 1 항에 있어서,
    상기 단리된 펩타이드는 라세미화에 덜 영향받는 것을 특징으로 하는 단리된 펩타이드.
  30. 제 1 항에 있어서,
    상기 변형된 잔기는 큐프레독신의 하나 이상의 아미노산 잔기를 포함하는데, 상기 아미노산 잔기는 그의 D-이성질체로 치환되는 것을 특징으로 하는 단리된 펩타이드.
  31. 제 30 항에 있어서,
    상기 큐프레독신의 아미노산 잔기 각각은 그의 D-이성질체로 치환되는 것을 특징으로 하는 단리된 펩타이드.
  32. 제 1 항에 있어서,
    상기 큐프레독신은 서열번호:45를 포함하는 것을 특징으로 하는 단리된 펩타이드.
  33. 제 1 항에 있어서,
    상기 단리된 펩타이드는 분해(degradation)에 덜 영향받는 것을 특징으로 하는 단리된 펩타이드.
  34. 제 1 항에 있어서,
    상기 변형된 잔기는 상기 큐프레독신 중 N-말단의 아세틸화를 포함하는 것을 특징으로 하는 단리된 펩타이드.
  35. 제 1 항에 있어서,
    상기 변형된 잔기는 상기 큐프레독신의 C-말단의 아미드화를 포함하는 것을 특징으로 하는 단리된 펩타이드.
  36. 제 1 항에 있어서,
    상기 변형된 잔기는 펩타이드의 삼차원 구조 안정성을 증가시키는 것을 특징으로 하는 단리된 펩타이드.
  37. 제 36 항에 있어서,
    상기 변형된 잔기는 적어도 하나의 α-나선의 안정성을 증가시키는 것을 특징으로 하는 단리된 펩타이드.
  38. 제 36 항에 있어서,
    상기 변형된 잔기는 락탐 브릿지를 포함하는 것을 특징으로 하는 단리된 펩타이드.
  39. 제 36 항에 있어서,
    상기 변형된 잔기는 비-천연(unnatural) 아미노산을 포함하는 것을 특징으로 하는 단리된 펩타이드.
  40. 제 36 항에 있어서,
    상기 변형된 잔기는 α-아미노-이소부티르산을 포함하는 것을 특징으로 하는 단리된 펩타이드.
  41. 제 1 항에 있어서,
    글리신, 프롤린, 세린, 아스파르트산, 알라닌, 트레오닌, 발린, 글루타민, 아스파라긴, 시스테인, 히스티딘, 리신 및 아르기닌으로 구성되는 군으로부터 선택되는 큐프레독신 유래된 펩타이드의 하나 이상의 아미노산 잔기는, 루신, 이소루신, 페닐알라닌, 글루탐산, 티로신, 트립토판, 메티오닌 및 α-아미노-이소부티르산으로 구성되는 군으로부터 선택되는 아미노산 잔기로 치환되는 것을 특징으로 하는 단리된 펩타이드.
  42. 제 1 항에 있어서,
    상기 단리된 펩타이드는 서열번호:34 내지 서열번호:44로 구성되는 군으로부터 선택되는 아미노산 서열을 포함하는 것을 특징으로 하는 단리된 펩타이드.
  43. 제 1 항에 있어서,
    상기 큐프레독신의 두 개 이상의 리신 잔기는 i(i+4) 간격으로 ε-(3,5-디니트로벤조일)-리신 잔기로 치환되는 것을 특징으로 하는 단리된 펩타이드.
  44. 제 1 항에 있어서,
    상기 큐프레독신은 서열번호:1을 포함하고, 상기 변형된 잔기는 서열번호:1의 53번 내지 56번, 58번 내지 64번 및 68번 내지 70번으로 구성되는 군으로부터 선택되는 하나 이상의 위치에 존재하는 것을 특징으로 하는 단리된 펩타이드.
  45. 제 1 항에 있어서,
    상기 변형된 잔기는 자생 아미노산과 일치하는 올레핀-함유 테더(tether)를 포함하는 α,α-이치환된 비-천연 아미노산으로 치환된 큐프레독신의 하나 이상의 자생 아미노산 잔기쌍을 포함하는 것을 특징으로 하는 단리된 펩타이드.
  46. 제 45 항에 있어서,
    상기 큐프레독신은 서열번호:1을 포함하고, 상기 변형된 잔기는 서열번호:1의 53 내지 56번, 58 내지 64번 및 68번 내지 70번으로 구성되는 군으로부터 선택되는 하나 이상의 위치에 존재하는 것을 특징으로 하는 단리된 펩타이드.
  47. 제 1 항에 있어서,
    상기 변형된 잔기는, 카뎁신 B-절단가능한 결합을 통해, Pep42(서열번호:3505)에 융합된 잔기를 포함하는 것을 특징으로 하는 단리된 펩타이드.
  48. 제 1 항에 있어서,
    상기 변형된 잔기는 광학적으로 활성인 아미노산을 포함하는 것을 특징으로 하는 단리된 펩타이드.
  49. 제 1 항에 따른 단리된 펩타이드 및 약학적으로 허용가능한 담체를 포함하는 약학 조성물.
  50. 제 1 항에 따른 단리된 펩타이드의 치료적 유효량을 포유류에게 투여하는 단계를 포함하는 방법.
  51. 제 50 항에 있어서,
    상기 포유류는 인간인 것을 특징으로 하는 방법.
  52. 큐프레독신의 약물 동력학 성질을 향상시키는 방법에 있어서, 상기 방법은:
    큐프레독신 중 하나 이상의 아미노산 잔기를 변형하는 단계를 포함하며, 상기 변형은 야생형 큐프레독신의 약학적 활성 중 적어도 하나를 보유하는 것을 특징으로 하는 큐프레독신의 약물 동력학 성질 향상 방법.
  53. 제 52 항에 있어서,
    상기 변형하는 단계는 하나 이상의 잔기의 고리화 반응 단계를 포함하는 것을 특징으로 하는 큐프레독신의 약물 동력학 성질 향상 방법.
  54. 제 52 항에 있어서,
    상기 변형하는 단계는, 상기 큐프레독신 중의 천연 아미노산을 비-천연 아미노산으로 치환하는 단계를 포함하는 것을 특징으로 하는 큐프레독신의 약물 동력학 성질 향상 방법.
  55. 제 52 항에 있어서,
    상기 변형하는 단계는 상기 큐프레독신의 α-나선 부분을 증가시키는 단계를 포함하는 것을 특징으로 하는 큐프레독신의 약물 동력학 성질 향상 방법.
  56. 제 52 항에 있어서,
    상기 변형하는 단계는 상기 큐프레독신에 락탐 브릿지를 첨가하는 단계를 포함하는 것을 특징으로 하는 큐프레독신의 약물 동력학 성질 향상 방법.
  57. 제 52 항에 있어서,
    상기 변형하는 단계는 비-천연 아미노산을 효소성 번역계(enzymatic translation system)에 첨가하는 단계를 포함하는 것을 특징으로 하는 큐프레독신의 약물 동력학 성질 향상 방법.
  58. 제 52 항에 있어서,
    상기 큐프레독신은 서열번호:13 또는 서열번호:13의 절단을 포함하는 것을 특징으로 하는 큐프레독신의 약물 동력학 성질 향상 방법.
  59. 제 52 항에 있어서,
    상기 큐프레독신은 서열번호:1 또는 서열번호:1의 절단을 포함하는 것을 특징으로 하는 큐프레독신의 약물 동력학 성질 향상 방법.
  60. 제 1 항에 있어서,
    상기 단리된 펩타이드는 나노입자(nanoparticle)와 결합되는 것을 특징으로 하는 단리된 펩타이드.
  61. 제 60 항에 있어서,
    상기 나노입자는 귀금속인 것을 특징으로 하는 단리된 펩타이드.
  62. 제 61 항에 있어서,
    상기 귀금속은 금인 것을 특징으로 하는 단리된 펩타이드.
  63. 제 60 항에 있어서,
    상기 단리된 펩타이드는 전자 이동 경로를 통해 나노입자와 결합되는 것을 특징으로 하는 단리된 펩타이드.
KR1020117021741A 2009-02-19 2010-02-19 큐프레독신 유래 펩티드의 변형 및 이의 사용방법 KR20110128878A (ko)

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US12/389,120 US9434770B2 (en) 2004-10-07 2009-02-19 Modified cupredoxin derived peptides

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