KR20110032746A

KR20110032746A - Composition for skin regeneration

Info

Publication number: KR20110032746A
Application number: KR1020090090397A
Authority: KR
Inventors: 조창묵
Original assignee: 조성코퍼레이션 주식회사
Priority date: 2009-09-24
Filing date: 2009-09-24
Publication date: 2011-03-30

Abstract

The present invention is organocalcium or biosilica crystals in the form of fine needles; And extracts of two or more natural plants selected from the group consisting of horsetail, liver leaf plantain, sage leaf, rose of sharon, spirulina, calendula, hamamelis, trigonelia and melissa, and having a pH of 5.5 to 7.5. It relates to a composition for skin regeneration.

Organocalcin crystals, biosilica crystals, extracts

Description

Composition for Skin Regeneration {COMPOSITION FOR SKIN REGENERATION}

The present invention relates to a composition for skin regeneration using natural extracts for biological skin regeneration.

Human skin has a function of protecting the body by acting as a boundary for protecting the human body from an external harmful environment. This skin consists of the epidermis, dermis and subcutaneous fat layer. Of these, the epidermis is located on the outermost side of the skin, and the epidermis determines the visible skin texture and color. The epidermis is composed of keratinocytes, melanocytes, Langerhans cells, and Merkel cells, of which keratinocytes make up most of the epidermis. The keratinocytes are composed of four layers, from the innermost to the base layer, the pole layer, the granule layer, and the stratum corneum.

Skin cells are constantly produced in the basal layer and exfoliate to the stratum corneum.

About four weeks of time to avail, they fall into dead cells. As time passes, the skin is attacked by the external environment, ages, and elasticity decreases and wrinkles occur. This aging of the skin causes the surface to appear dry or rough.

As such, numerous skin regeneration methods have been developed and used to prevent aging of the skin or to improve aging skin. However, many pain and pigmentation, sensitive skin, or skin troubles have been observed.

Humans have developed a number of methods of peeling to improve aged skin or skin damaged by acne, wounds and the like. These peelings have methods to induce new skin regeneration by peeling or hurting existing skin. These methods include physical methods of cutting the epidermis using expensive special equipment such as laser treatment, IPL, etc. Also, many chemical peelings are performed by chemical methods of melting or shaving the epidermis using acid or abrasives. Acid peeling has been developed, but they also damage the epidermis first, so they cannot protect the skin from the harmful environment during the skin regeneration period, causing many side effects, and they are toxic and must be treated with special gloves or expensive equipment. It was possible, and with pain, it was necessary to use partial anesthesia or anesthetic ointment.

It is an object of the present invention to penetrate the skin with bare hand pressure and stimulate keratinocytes without the use of conventional physical or chemical methods and without the use of anesthetics or anesthetic ointments. It is to provide a composition for skin regeneration that can induce regeneration.

In addition, the object of the present invention is to aging skin or various problem skin, that is, sensitive skin, acne skin, blemished skin, large pores skin, sagging skin by new skin is regenerated by the existing epidermis to fall off dead cells To provide a composition for skin regeneration to improve skin with symptoms of hot flashes, burns or wounds.

The present invention is organic calcium or biosilica crystals present in nature in the form of fine needles; And extracts of one or more natural plants selected from the group consisting of horsetail, liver leaf plantain, sage leaf, rose of sharon, spirulina, calendula, hamamelis, trigonelia and melissa, and having a pH of 5.5 to 7.5 It provides a composition for skin regeneration characterized in.

The composition for skin regeneration of the present invention does not use existing physical or chemical methods and does not use anesthetics or anesthetic ointment, and penetrates the skin at bare pressure to stimulate keratinocytes, thereby maintaining existing epidermal cells intact. It can induce skin regeneration in the condition. The composition for skin regeneration of the present invention allows the old epidermis to fall into dead cells as new skin is regenerated, thereby aging skin or various problem skin, ie sensitive skin, acne skin, blemished skin, large pores, sagging skin. It can improve skin, skin with hot flashes, skin with burns or cuts.

EMBODIMENT OF THE INVENTION Hereinafter, this invention is demonstrated in detail.

The composition for skin regeneration of the present invention includes organic calcium or biosilica crystals and natural plant extracts that are degraded in vivo.

The organocalcium or biosilica crystals included in the composition for skin regeneration of the present invention are 100% biodegradable when penetrated into the living body in the form of fine saliva extracted from natural plants. The organocalcium or biosilica crystals are not particularly limited as long as they are used in the art, but the main component is organic calcium or biosilica, which is a natural substance present in giant plasma cells of plants such as horsetail, liver leaf plan, and hamamelis. It is preferably a complex of insoluble materials.

Complexes extracted from these plants are characterized by a mixture of organocalcium and biosilica, and are limited to 100% degradation in vivo even when used in combination or in combination with organic calcium crystals and biosilica crystals in the mixture extracted from these natural products.

The organocalcium or biosilica crystals penetrate the skin at the pressure of bare hands, thereby stimulating keratinocytes, thereby inducing skin regeneration in the state where the existing epidermal cells remain. The skin is regenerated by the organic calcium crystals, which causes the existing epidermis to fall into dead cells, thereby improving aging skin or various problem skins. The organocalcin crystals penetrate into the skin and then biodegrade 100% for 48 hours.

The organocalcium or biosilica crystals are preferably contained in 10 to 90% by weight, more preferably 20 to 60% by weight based on the total weight of the composition.

If it is included below the above range, the effect of inducing skin regeneration is sharply lowered, if exceeding the above range, the pain of the patient during the skin penetration may be severe and damage to the epidermis.

The crystal of the organocalcium or biosilica is preferably 10 to 500㎛ in length, 1 to 20㎛ in thickness. If it has a length and thickness less than the above-mentioned range, it is not easy to penetrate the skin, and if it has a length and thickness exceeding the above-mentioned range, it is not suitable because the pain of the patient is caused during skin penetration.

Extract of the natural plant included in the composition for skin regeneration of the present invention is two or more selected from the group consisting of horsetail, liver leaf plantain, sage leaves, rose of sharon, spirulina, calendula, hamamelis, trigonelia and melissa. Extract of the natural plant is preferred to use those made of fine powder after drying the natural plant.

The extract of the natural plant prevents side effects that occur when the organic calcium or biosilica crystals penetrate into the skin, and penetrates into the skin through the fine saliva made of the organic calcium or biosilica crystals. In more detail, the extract of the natural plant can help skin regeneration while preventing skin damage and preventing infections with bacteria. In addition, by being used together with the organic calcium or bio-silica crystals, it is more effective in regenerating and elasticity of the skin, such as antibacterial, anti-inflammatory, anti-inflammatory.

Extract of the natural plant is preferably included in 10 to 90% by weight relative to the total weight of the composition. If the above range is satisfied, it is possible to prevent skin damage and to prevent skin infection, and to help skin regeneration.

The extract of horsetail can improve blood circulation and induce collagen synthesis, which is effective in elasticity of the skin layer. The extract of horsetail is preferably included in an amount of 3.0 to 15.0% by weight based on the total weight of the composition.

Extract of the liver leaf plantain has an antibacterial anti-inflammatory effect. Extract of the liver leaf wonder is preferably included in 1.0 to 10.0% by weight based on the total weight of the composition.

The extract of the sage leaf has antibacterial effects and plays a role of sterilization and antiseptic. The extract of the sage leaf is preferably included in 5.0 to 15.0% by weight based on the total weight of the composition.

The Mugunghwa leaf extract soothes or softens the heat or pain that may appear when fine saliva penetrates the skin. The extract of Mugunghwa is preferably included in an amount of 0.5 to 10.0% by weight based on the total weight of the composition.

The extract of Spirulina has the effect of increasing white blood cells when penetrating into the skin to increase the emollient power. The total amount of the spirulina extract composition is preferably included in an amount of 0.1 to 7.5 wt%.

The calendula extract effectively calms heat generated when the composition for skin regeneration of the present invention is applied to sensitive skin. The calendula extract is preferably included in the total weight of the composition, 0.1 to 7.5% by weight.

The extract of the hamamelis is effective in treating when the skin is inflamed, it serves to prevent skin inflammation. The Hamamelis extract is preferably contained in 0.5 to 15.0% by weight based on the total weight of the composition.

The trigonelia extract is effective in preventing hair loss. The trigonelia extract is preferably included in an amount of 0.1 to 5.0 wt% based on the total weight of the composition.

The extract of Melissa has the effect of improving sedation and blood circulation. The extract of the Melissa is preferably contained in 0.5 to 5.0% by weight based on the total weight of the composition, if the above range is satisfied, the blood circulation can be improved to improve the skin circulation more smoothly.

The composition for skin regeneration of the present invention does not use existing physical or chemical methods and does not use anesthetics or anesthetic ointment, and penetrates the skin at bare pressure to stimulate keratinocytes, thereby maintaining existing epidermal cells intact. It can induce skin regeneration in the condition. The composition for skin regeneration of the present invention can improve the aged skin or various problem skin by letting the existing epidermis fall into dead cells as new skin is regenerated.

Next, Examples and Comparative Examples of the present invention are described. However, these examples are only for illustrating the present invention in more detail, the present invention is not limited to these examples.

Example 1 To Example 4 And Comparative example 1: Preparation of skin regeneration composition

A composition for skin regeneration was prepared at the composition ratios shown in Table 1. here,

Natural extract was used to dry the natural plant and then prepared in fine powder.

Organocalcium or biosilica crystals weight% Natural extracts weight% Example 1 Krauter Concentrate
(Retipalm GmbH) 61.3 Horsetail 6.70 Liver leaf plan 3.80 Sage leaves 8.00 Rose of Sharon 4.50 Spirulina 2.70 Calendula 2.40 Hamamelis 7.90 Trigonelia 1.70 balm 2.00 sub Total 61.3 sub Total 39.70 Example 2 Krauter Concentrate
(Retipalm GmbH) 59.9 Horsetail 5.50 Liver leaf plan 4.50 Sage leaves 6.80 Rose of Sharon 4.50 Spirulina 2.70 Calendula 2.40 Hamamelis 9.00 Trigonelia 3.50 balm 1.20 sub Total 59.9 sub Total 40.10 Example 3 Krauter Concentrate
(Retipalm GmbH) 39.7 Horsetail 12.00 Liver leaf plan 6.50 Sage leaves 11.00 Rose of Sharon 5.90 Spirulina 4.80 Calendula 3.50 Hamamelis 10.50 Trigonelia 2.80 balm 3.30 sub Total 39.7 sub Total 60.30 Example 4 Krauter Concentrate
(Retipalm GmbH) 44.4 Horsetail 13.50 Liver leaf plan 8.30 Sage leaves 6.80 Rose of Sharon 1.00 Spirulina 5.00 Calendula 5.00 Hamamelis 8.00 Trigonelia 4.00 balm 4.00 sub Total 44.4 sub Total 55.60 Comparative Example 1 Krauter Concentrate
(Retipalm GmbH) 7.0 Horsetail 10.00 Liver leaf plan 10.00 Sage leaves 15.00 Rose of Sharon 12.00 Spirulina 7.00 Calendula 7.00 Hamamelis 12.00 Trigonelia 10.00 balm 10.00 sub Total 7.0 sub Total 93.00

Test Example : Evaluation of properties of skin regeneration composition

Compositions of Examples 1 to 4 are sensitive skin, acne skin, aging and blemished skin, large pores and sagging skin, large pores and hot flashes, large pores in the nose and chin It was applied to skin and skin with acne scars.

1 is a front photograph of a patient before applying the composition of Example 1 to sensitive skin.

2 is a front photograph of a patient when the composition of Example 1 is applied three days after application to sensitive skin. Figure 3 is a side view of the patient at 3 days after application of the composition of Example 1 to sensitive skin. 4 is a front photograph of a patient when exfoliation is completed 6 days after applying the composition of Example 1 to sensitive skin.

1 to 4, after 3 days of applying Example 1, the composition for skin regeneration of the present invention to the skin, exfoliation naturally begins, and after 6 days the exfoliation is complete, the skin was sensitive to normal skin It can be seen that improved.

5 is a front photograph of a patient before applying the composition of Example 1 to acne skin. 6 is a front photograph of a patient before applying the composition of Example 1 to acne skin.

5 and 6, it can be seen that when applying Example 1, the composition for skin regeneration of the present invention to the skin, acne and skin elasticity is improved.

7 is a front photograph of a patient before applying the composition of Example 2 to aged and blemished skin. 8 is a front photograph of a patient after applying the composition of Example 2 to aged and blemished skin.

Referring to FIGS. 7 and 8, it can be seen that when applying Example 2, which is a composition for skin regeneration of the present invention, to skin, skin wrinkles and blemishes are improved.

FIG. 9 is a side photograph of a patient before applying the composition of Example 2 to large, bulging skin. 10 is a side photograph of a patient after applying the composition of Example 2 to large, bulging skin.

9 and 10, it can be seen that when applied to the skin Example 2, the composition for skin regeneration of the present invention, there is a pore reduction and lifting effect.

11 is an enlarged photograph of a patient's skin before applying the composition of Example 3 to the skin with large pores and hot flashes. 12 is an enlarged photograph of a patient's skin showing the exfoliation phenomenon after applying the composition of Example 3 to the skin with large pores and hot flashes. FIG. 13 is an enlarged photograph of a patient's skin when exfoliation is completed after applying the composition of Example 3 to the skin with large pores and hot flashes.

11 to 13, when applying Example 3, the composition for skin regeneration of the present invention to the skin, the keratin elimination occurs and keratin collapse is completed, the pores shrinkage phenomenon and facial flushing symptoms can be seen to improve have.

14 is a front photograph of a patient before applying the composition of Example 4 to the skin with large pores in the nose and with chin. FIG. 15 is a front photograph of a patient after applying the composition of Example 4 to the skin with large pores in the nose and chin.

Referring to FIGS. 14 and 15, it can be seen that when Example 4, which is a composition for skin regeneration of the present invention, is applied to the skin, it has a pore reduction effect and an improvement in acne.

Figure 16 is a side view of the patient before applying the composition of Example 4 to the skin with large pores and acne scars. Figure 17 is a side view of the patient after applying the composition of Example 4 to the skin with large pores and acne scars.

Referring to FIGS. 16 and 17, when Example 4, which is a composition for skin regeneration of the present invention, is applied to the skin, it can be seen that there is a pore reduction effect and acne scars are improved.

Therefore, using the composition for skin regeneration of the present invention, the scar due to acne or acne can be significantly improved, and also the pores are reduced, it can be improved to a more elastic skin due to the lifting effect. It also has an effect on wrinkle improvement and removal of blemishes.

Test results for acne scars and pores shrinkage using Comparative Example 1 has no picture, but the amount of keratin drop significantly decreased as the content of organic calcium crystals decreased, the skin regeneration effect did not appear significantly.

1 to 17 is a composition corresponding to the claims applied to various types of skin

Shows the result of the photo

Claims

Organocalcium or biosilica crystals in the form of fine saliva; And horsetail,

Liver leaf plantain, sage leaf, rose of sharon, spirulina, calendula, hamamelis, trigonelia and melissa extracts of two or more natural plants selected from the group consisting of,

Skin regeneration composition, characterized in that the pH is 5.5 to 7.5.

The method according to claim 1,

Regarding the total weight of the composition,

10 to 90% by weight of the organocalcium or biosilica crystals; And

Characterized in that it comprises 90 to 10% by weight of the extract of the natural plant

Skin regeneration composition.

The method according to claim 2,

Regarding the total weight of the composition,

10 to 90% by weight of the organocalcium or biosilica crystals; And

Extract of the natural plant,

3.0 to 15.0 wt% extract of the horsetail, extract of the liver leaf plantain

1.0 to 10.0% by weight, 5.0 to 15.0% by weight of the extract of the sage leaf, the

0.5 to 10.0% by weight of the extract of Rose of Sharon, 0.1 to 7.5% by weight of the extract of Spirulina, 0.1 to 7.5% by weight of the extract of Calendula, 0.5 to 15.0% by weight of the extract of Hamamelis, 0.1 to 0.1 of the extract of Trigonelia 5.0% by weight, 0.5 to 5.0% by weight of the extract of the melissa comprises two or more selected from the group consisting of

Skin regeneration composition, characterized in that.

The method according to claim 1,

The organocalcium or biosilica crystals have a length of 10 to 500 µm and a thickness of 1

Skin regeneration composition, characterized in that from 20 to 20 ㎛.