RU2352329C1 - Method of treatment of age and cosmetic defects of face skin - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention concerns medicine, namely, cosmetology and can be used for correction of age and cosmetic defects of the face skin. The method includes application of an agent of following structure: phenol 32-35 wt %; oil of calendula 5.0-5.54 wt %; glycerin 11.9-12.59 wt %; betadyne 8.87-9.46 wt %; thiamin 0.038-0.042 wt %; riboflavin 0.028-0.032 wt %; ascorbic acid 0.048-0.052 wt %; water of double distilling - 39.5-40.27 wt % under an adhesive mask on a face skin for 30-36 hours. After removal of the given agent, an agent for transfer of colliquative necrosis in dry before formation of a dry crust is placed on a skin within 6-8 days 2 times a day. Then for 20-25 hours the ointment containing zinc oxide, then the necrotising layer of the skin is removed and Celestioderm-B with Garamycinum is placed under the wadded layer. Then within two months, sun-protection and nutritious creams are placed on a skin, besides, after removal of a phenol-containing agent, in addition a cream containing silver is applied on the skin of eyelids within 2-4 days two times a day.

EFFECT: proposed method allows to reduce treatment terms at the expense of complex influence, to warn postoperative complications and to improve cosmetic results.

4 cl, 1 ex

Description

The invention relates to medicine, namely to corrective dermatology. It can be used to correct various cosmetic skin defects.

The outcome of skin diseases, the result of biological aging, as a rule, are significant defects in the skin of the face: wrinkles, degenerative atrophies, keratoses, senile warts, changes in pigmentation, capillaryectasia, scars, etc., which often bring their owners great mental trauma. One of the urgent problems of modern cosmetics is the problem associated with the improvement, rejuvenation of the skin, and especially the face.

The known method of corrective dermatology, dermabrasion, which consists in removing the epidermis with the tips of the dermal papillae using special tools: grinding discs and milling cutters (Ferzhgek O. Cosmetics and Dermatology. M .: Medicine, 1980, p.113-119). This method is indicated when signs of aging appear, especially with wrinkles. However, it requires special expensive equipment and complex technical skills. The results of dermabrasion depend on the quality of the instruments used. During an operation on an uneven face relief, it is difficult to dose the depth of the removed skin layer.

There are also known methods for the correction of cosmetic defects of the skin of the face, based on the application of therapeutic solutions containing phenol (Ferzhgek O. Cosmetics and dermatology. M: Medicine, 1980, p.136-137). The phenol-containing solution is applied until a white coating appears. At the end of the operation, the skin is dusted with an indifferent powder. As a result of the treatment, exfoliation of the skin occurs, which eliminates significant cosmetic defects of the skin. However, phenol is very rapidly absorbed by the skin. Repeated application of phenol to large areas is dangerous due to the possibility of quickly reaching a toxic dose to the patient. The large uncontrolled depth of necrosis with excessive application of phenol prevents the physiological tissue regeneration in this zone.

A known method of treating age-related and cosmetic defects of the skin of the face, selected as a prototype, comprising applying to it for 30-36 hours under an adhesive mask, means including liquid phenol, vegetable oils and water, after removing the mask is applied to the skin for 6-8 days 2 times a day, a means for converting collication necrosis to dry until a dry crust forms, then an ointment containing zinc oxide is applied under the cotton layer for 20-25 hours, after which the necrotic layer of the skin is removed and then applied for two months t on the skin of sunscreens and nourishing creams, in addition, after removing the phenol-containing agent, an additional cream containing silver is applied twice a day twice a day to the skin of the eyelids (patent of the Russian Federation No. 21114614).

The objective of the proposed method is to reduce the treatment time to prevent relapse and postoperative complications and improve cosmetic results.

A method of treating age-related and cosmetic defects of the skin of the face includes applying to it for 30-36 hours under an adhesive mask a tool, including liquid phenol, vegetable oils and water, after removing the mask, apply the agent to the skin for 6-8 days 2 times a day collision necrosis in dry until dry crust is formed, then an ointment containing zinc oxide is applied under the cotton layer for 20-25 hours, then the necrotic layer of the skin is removed and then sunscreens and a nourishing cream are applied to the skin for two months in addition, after removing the phenol-containing agent, an additional cream containing silver is applied to the skin of the eyelids for 2-4 days twice a day, according to the invention, after removing the necrotic layer of the skin, celestoderm-B with Garamycin is applied, in addition to phenol, vegetable oils and water means includes an antifungal drug and a vitamin complex in the following ratio of components, wt.%:

phenol 32-35 marigold oil 5.0-5.54 glycerol 11.9-12.59 betadine 8.87-9.46 thiamine 0.038-0.042 riboflavin 0.028-0.032 vitamin C 0,048-0,052 double distillation water 39.5-40.27

Means for converting collicational necrosis to dry includes xeroform.

In addition to zinc oxide, an ointment contains a cream containing silver: agrosulfan or dermazine.

Before and during the use of nourishing creams, thermal water and collagen cream are applied to the face.

In the treatment of age-related and cosmetic defects of the skin of the face by applying an application of a phenol-containing solution, the effect is achieved by optimizing the penetration depth of the damaging agent - phenol and limiting it to the level of the tips of the papillary dermis. The ratio of components and the selection of components obtained empirically after conducting preclinical and clinical studies. The positive results of these studies allowed us to determine the sequence of actions. Empirically selected components of the phenol-containing agent in the original ratio have a reliable protective effect on the deep layers of the dermis, trapping phenol mainly in the epidermis and papillary dermis.

Consistent application of drugs that contribute to the development of collicative necrosis in dry, the use of emollients in the form of liquid paraffin, as well as the use of zinc oxide with the addition of agrosulfan or dermazine provide a radical removal of the necrotic surface layer of the skin, create favorable conditions for its regeneration. Agrosulfan and dermazine have a wide antibacterial spectrum and are active against almost all microorganisms that can infect the skin of the face.

The use of a vitamin complex in a solution: riboflavin, ascorbic acid and thiamine, not only protect the skin, but also by saturating it with vitamins, it reduces the recovery time of the skin.

The used antifungal drug betadine protects the skin from possible fungal and viral infections at this time.

Xeroform - a bismuth-based drug has an astringent, drying and antiseptic effect.

Celestoderm-B with haramycin as an active substance contains betamethasone valerate and has anti-inflammatory and anti-allergic effects, while it has anti-edematous activity, reduces vascular permeability, which is necessary for young thin skin after removing the crust, which was protected for several days.

The application of thermal water, which reduces the sensitivity of cells involved in the reactivity mechanism, improves intercellular metabolism, strengthens cell membranes, restores skin balance, and stimulates immune defense cells. The use of collagen cream, necessary to improve the condition of the skin, because hydrolyzed collagen contains phospholipids that help moisturize the skin, which improves cell proliferation and growth factor transfer, enhances the production of own collagen fibers and helps restore skin thickness.

Consistent application of drugs that contribute to the development of collicational necrosis and its transition to dry, as well as special techniques that facilitate the removal of dry necrosis (softening, the use of zinc oxide), reduce the invasiveness of the operation, reduce time and provide radical removal of the necrotic surface layer of the skin, create favorable conditions for her regeneration.

The above distinguishing features are new in comparison with the prototype, so the invention meets the criterion of "novelty."

Studies on the sources of patent and scientific and technical information showed that in the studied prior art there are no similar technical solutions, i.e. The claimed technical solution does not follow explicitly from the studied prior art and thus meets the criterion of "inventive step".

This technical solution can be applied in hospitals on standard equipment with standard tools for plastic surgery, therefore, it meets the criterion of "industrial applicability".

The method is as follows. In the operating room, degrease the skin of the face, for example, by means of a swab dipped in ether or acetone. Then a strongly pressed cotton swab is applied to the face with the following composition, wt.%: Phenol 32-35; marigold oil 5.0-5.54; glycerol 11.9-12.59; betadine 8.87-9.46; thiamine 0.038-0.042; riboflavin 0.028-0.032; ascorbic acid 0.048-0.052; double distillation water 39.5-40.27.

Cover the face with adhesive tape. After 30-36 hours, the adhesive mask is removed. Then, for 6-8 days, xeroform is applied 2 times a day until a dry crust is formed. In this case, any of a number of known agents can be used to ensure the conversion of collication necrosis to dry. Dusting with xeroform is carried out with light patting movements using a cotton swab. Then the dry skin crust is softened using a fat-soluble agent, for example petroleum jelly.

After that, zinc oxide cream containing agrosulfan or dermazine is applied to the face and covered with cotton wool for 20-25 hours. Next, the necrotic skin layer is removed along with the cotton mask in a blunt way with an oil swab. During this period, celestoderm-B with Garamycin is applied to the face to relieve edema and inflammatory processes. Then, in the postoperative period, sunscreen and nourishing creams are applied to the face. As one of the nourishing creams, a cream containing 10-30% zinc oxide can be used.

To improve the condition of the skin before and during the use of all procedures, thermal water and a collagen cream are used.

Given the thin layer of skin on the eyelids, to increase the effectiveness of limiting the zone of dry necrosis, an additional cream containing silver is used. It is applied after removal of the phenol-containing agent for 2-4 days 2 times a day. A cream containing silver is used in combination with a remedy that provides for the conversion of collication necrosis to dry.

The proposed method allows you to radically correct various cosmetic defects anatomically capturing the epidermis and papillary dermis. It can be used to improve the entire surface of the skin of the face, for example, during aging, the presence of common hyperpigmented areas.

The present method can be recommended in the treatment of single defects, using it in areas of limited area, for example, with scars, capillaryectasia, wrinkles of the upper lip, forehead, chin, wrinkles and excess skin of the lower eyelid.

The specific composition of the phenolic-containing protective agents is determined individually depending on the type of skin, age, gender and nature of the cosmetic defect.

Clinical example. A 31-year-old, somatically healthy patient was admitted with complaints of uneven skin, changes in skin color in the direction of hyperpigmentation. Objectively: the face is symmetrical. Skin color is uneven due to common foci of hyperpigmentation. The pigment is grouped as much as possible on the buccal region, where it has a high intensity and practically merges. Foci of hyperpigmentation are also on the temporal region. Facial skin is hyperpigmented on 2/3 of its area. The surface of the epidermis is uneven. There are multiple scars ranging in size from 0.7-0.4 to 0.3-1.0 cm, with uneven edges. Against the background of hyperpigmented skin, the color of the scars is almost white. Skin roughness is also caused by enlarged pores. This picture is the result of untreated acne. A nasolabial fold is expressed and a wrinkle running parallel to it, starting from the inner corner of the eye and passing to the cheek. Wrinkle depth up to 1.5 mm. There are also excess skin of the upper eyelid of moderate degree. The angle of the mouth is somewhat omitted, continues into a wrinkle up to 2.0 mm long, 1.5 mm deep. Face oval saved.

Correction of cosmetic defects of the skin of the face by the proposed method under intubation anesthesia. In order to degrease with a gauze swab dipped in ether, the skin of the face has been treated. The phenol-containing agent is prepared using known techniques for mixing and dispersing the oil phase.

Then, a strongly wrung cotton swab dipped in the proposed phenol-containing product was applied lightly to the skin of the face, starting from the cheeks, moving further towards the nose, then towards the lower and upper lips. Rubbing the solution was carried out for 15 minutes Then they rubbed the phenol-containing product into the mouth and forehead, stopping at deeper wrinkles. Next, the skin of the eyebrows and nose was treated. The total processing time of 45 minutes A double-row adhesive plaster is glued to the face. During the manipulation, the monitoring parameters were normal. The patient was transferred to the ward. After 36 hours, the adhesive mask was removed with great care. Moderate edema and hyperemia of the skin of the face are noted. Every day for a week, twice a day, they sprinkled their face with lightly tapping movements with a cotton swab, powder containing xeroform. The patient did not experience pain. In parallel with the above dusting, during the first three days after removing the adhesive mask, a cream containing silver was applied to the eyelids 2 times a day.

In the areas powdered with xeroform, after 7 days from the start of powdering, the skin was a dry crust of dark brown color with many small cracks. The face in the areas covered with a crust is saturated with liquid paraffin with a cotton swab to soften it. A cream containing 20% zinc oxide, as well as agrosulfan or dermazine, is applied to the face with a small wooden spatula, and it was covered with a cotton mask, which is fixed with adhesive plaster. After 24 hours, a cotton mask was carefully removed along with a necrotic layer of skin. To do this, the face is treated with a cotton swab soaked in liquid paraffin. After that, the face is drained with sterile blotting paper and anti-inflammatory, anti-allergic and anti-flow agents, such as celestoderm-B with Garamycin, are applied. Starting from the next day, for two months, sunscreen was applied daily to the skin of the face, which was covered with foundation in combination with a nourishing cream. At the same time, thermal water and collagen cream were treated. On the 12th day after applying the phenol-containing agent, the patient was discharged for outpatient treatment. During her stay in the hospital she took only cold and warm liquid food through a wide tube. The high-calorie tube diet contained natural vegetable and fruit juices, yogurts, broths, mashed soups. In the postoperative period, for the prevention of purulent-inflammatory complications, hormonal, desensitizing and antibiotic therapy was carried out: prednisone 40 mg 1 time per day for three days, 20 mg 1 time per day for three days, suprastin 250 mg 2 times for 10 days, tsifran 500 mg 2 times a day for 8 days.

When examining 3 months after treatment by the proposed method: the complexion is even. No traces of hyperpigmentation were found. Skin irregularities caused by cicatricial changes are not visible. Marked relief in the area of the nasolabial folds and corners of the mouth. Excess skin of the upper eyelid is less pronounced.

Using the solution proposed for protection in comparison with all known means of a similar purpose provides the possibility of treating any skin pathology, reducing treatment time, eliminating postoperative relapses, and improving skin quality.

Claims (4)

1. A method of treating age-related and cosmetic defects of the skin of the face, comprising applying to it for 30-36 hours under an adhesive mask a means of including liquid phenol, vegetable oils and water, after removing which they are applied to the skin for 6-8 days 2 times a day to convert colliquational necrosis to dry until a dry crust is formed, then an ointment containing zinc oxide is applied under the cotton layer for 20-25 hours, after which the necrotic layer of the skin is removed and then sunscreens and nourishing creams are applied to the skin for two months, In addition, after removing the phenol-containing agent, an additional cream containing silver is applied to the skin of the eyelids for 2-4 days twice a day, characterized in that after removing the necrotic layer of the skin, celestioderm-B with Garamycin is applied, in addition to phenol, vegetable oils and water, the product includes an antifungal drug and a vitamin complex in the following ratio of components, wt.%:
phenol 32-35 marigold oil 5.0-5.54 glycerol 11.9-12.59 betadine 8.87-9.46 thiamine 0.038-0.042 riboflavin 0.028-0.032 vitamin C 0,048-0,052 double distillation water 39.5-40.27 2. A method of treating age-related and cosmetic defects of the facial skin according to claim 1, characterized in that the means for converting collision necrosis into dry includes xeroform. 3. A method of treating age-related and cosmetic defects in facial skin according to claim 2, characterized in that in addition to zinc oxide, a cream containing silver is included in the ointment: agrosulfan or dermazine. 4. A method of treating age-related and cosmetic defects in facial skin according to claim 3, characterized in that thermal water and a collagen cream are applied to the face before and during use of the nourishing creams.