KR20110015650A - 발사르탄의 펄스형 방출 - Google Patents

발사르탄의 펄스형 방출 Download PDF

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Publication number
KR20110015650A
KR20110015650A KR1020107029694A KR20107029694A KR20110015650A KR 20110015650 A KR20110015650 A KR 20110015650A KR 1020107029694 A KR1020107029694 A KR 1020107029694A KR 20107029694 A KR20107029694 A KR 20107029694A KR 20110015650 A KR20110015650 A KR 20110015650A
Authority
KR
South Korea
Prior art keywords
valsartan
component
delivery system
drug delivery
gastroretentive
Prior art date
Application number
KR1020107029694A
Other languages
English (en)
Korean (ko)
Inventor
아몰 싱그 마타루
아그네스 타일라르다트
로버트 프랭크 와그너
Original Assignee
노파르티스 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR20110015650A publication Critical patent/KR20110015650A/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020107029694A 2008-06-03 2009-06-01 발사르탄의 펄스형 방출 KR20110015650A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5823308P 2008-06-03 2008-06-03
US61/058,233 2008-06-03

Publications (1)

Publication Number Publication Date
KR20110015650A true KR20110015650A (ko) 2011-02-16

Family

ID=40974663

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107029694A KR20110015650A (ko) 2008-06-03 2009-06-01 발사르탄의 펄스형 방출

Country Status (10)

Country Link
US (1) US20110189286A1 (pt)
EP (1) EP2285358A1 (pt)
JP (1) JP2011522050A (pt)
KR (1) KR20110015650A (pt)
CN (1) CN102046154A (pt)
AU (1) AU2009256423A1 (pt)
BR (1) BRPI0913337A2 (pt)
CA (1) CA2726793A1 (pt)
MX (1) MX2010013238A (pt)
WO (1) WO2009148990A1 (pt)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013162114A1 (ko) * 2012-04-27 2013-10-31 씨제이제일제당 주식회사 위체류 약물전달 시스템을 이용한 서방성 제제
WO2018190451A1 (ko) * 2017-04-12 2018-10-18 대원제약주식회사 안지오텐신 수용체 길항제를 포함하는 약제학적 조성물
WO2022139495A1 (ko) * 2020-12-24 2022-06-30 주식회사 보령 사쿠비트릴 발사르탄 하이브리드 화합물 또는 그 약제학적으로 허용되는 염을 유효성분으로 포함하는 약제학적 조성물

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102028659A (zh) * 2010-12-16 2011-04-27 苏州大学 一种缬沙坦生物粘附性包衣微丸制剂及其制备方法
CN102133197B (zh) * 2011-03-18 2012-06-27 海南美兰史克制药有限公司 一种缬沙坦脂微球固体制剂
CN102626395B (zh) * 2012-04-19 2014-02-26 海南美兰史克制药有限公司 一种阿利克仑缬沙坦药物组合物脂质体固体制剂
CN102641253B (zh) * 2012-05-07 2013-10-09 山东省医药工业研究所 缬沙坦缓释片及其制备方法
CA2888135A1 (en) * 2012-10-14 2014-04-17 The Board Of Regents, The University Of Texas System Delivery of small interfering rna and micro rna through membrane-disruptive, responsive nanoscale hydrogels
KR102237799B1 (ko) 2012-11-14 2021-04-08 더블유.알. 그레이스 앤드 캄파니-콘. 생물학적 활성 물질 및 비-정렬된 무기 산화물을 함유하는 조성물
WO2015028972A1 (en) 2013-09-02 2015-03-05 Ranbaxy Laboratories Limited Pulsatile-release dosage form
WO2018002673A1 (en) * 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
CN113133978B (zh) * 2020-01-20 2023-10-17 鲁南制药集团股份有限公司 一种阿齐沙坦片及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008536929A (ja) * 2005-04-18 2008-09-11 ルビコン・リサーチ・ピーヴィーティー・エルティーディー 生体強化組成物
PE20080907A1 (es) * 2006-08-31 2008-08-22 Novartis Ag Sistema de suministro de farmaco oral gastro-retentivo de liberacion extendida para valsartan
WO2008064338A2 (en) * 2006-11-22 2008-05-29 Rubicon Research Pvt. Ltd. Valsartan formulation for pulsatile delivery
WO2008084504A2 (en) * 2007-01-12 2008-07-17 Rubicon Research Private Limited Pharmaceutical compositions of angiotensin ii receptor blockers
CA2694602A1 (en) * 2007-07-27 2009-02-05 Depomed, Inc. Pulsatile gastric retentive dosage forms

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013162114A1 (ko) * 2012-04-27 2013-10-31 씨제이제일제당 주식회사 위체류 약물전달 시스템을 이용한 서방성 제제
WO2018190451A1 (ko) * 2017-04-12 2018-10-18 대원제약주식회사 안지오텐신 수용체 길항제를 포함하는 약제학적 조성물
WO2022139495A1 (ko) * 2020-12-24 2022-06-30 주식회사 보령 사쿠비트릴 발사르탄 하이브리드 화합물 또는 그 약제학적으로 허용되는 염을 유효성분으로 포함하는 약제학적 조성물

Also Published As

Publication number Publication date
CA2726793A1 (en) 2009-12-10
AU2009256423A1 (en) 2009-12-10
BRPI0913337A2 (pt) 2017-05-23
US20110189286A1 (en) 2011-08-04
JP2011522050A (ja) 2011-07-28
CN102046154A (zh) 2011-05-04
WO2009148990A1 (en) 2009-12-10
EP2285358A1 (en) 2011-02-23
MX2010013238A (es) 2010-12-21

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