KR20110000250A - Health-supplementary food utilizing natural material for the healthy prostate and method of manufacturing thereof - Google Patents
Health-supplementary food utilizing natural material for the healthy prostate and method of manufacturing thereof Download PDFInfo
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- KR20110000250A KR20110000250A KR1020090057661A KR20090057661A KR20110000250A KR 20110000250 A KR20110000250 A KR 20110000250A KR 1020090057661 A KR1020090057661 A KR 1020090057661A KR 20090057661 A KR20090057661 A KR 20090057661A KR 20110000250 A KR20110000250 A KR 20110000250A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
- A23P10/35—Encapsulation of particles, e.g. foodstuff additives with oils, lipids, monoglycerides or diglycerides
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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Abstract
Description
본 발명은 천연물질을 사용한 건강식품 제조방법에 관한 것으로서, 보다 상세하게는 남성의 전립선을 보호할 수 있는 전립선을 위한 건강식품 제조방법에 관한 것이다.The present invention relates to a health food manufacturing method using a natural substance, and more particularly to a health food manufacturing method for the prostate gland can protect the male prostate.
최근 현대 남성의 경우 운동부족, 서구화된 음식문화, 스트레스 그리고 과도한 음주문화 등으로 인하여 전립선이 크게 약화되고 있다. 이러한 전립선의 약화는 빈번한 소변 횟수의 증가, 소변이 막힘, 가는 소변줄기, 배뇨곤란, 잔뇨감, 피로감, 조루, 정력감퇴, 성기능 장애 등과 같은 증상을 수반하게 되는데, 상기한 증상 이외에 여러 가지 합병증을 초래하게 된다.In modern men, the prostate gland is greatly weakened due to lack of exercise, westernized food culture, stress and excessive drinking culture. This weakening of the prostate is accompanied by a number of frequent urinations, clogging of urine, thin urine, difficulty urinating, residual urine, fatigue, premature ejaculation, loss of energy, sexual dysfunction, and many other complications. Done.
따라서, 전립선의 기능을 강화시키기 위해서는 꾸준한 운동요법과 함께 약재를 병행하는 것이 효과적인데, 양약의 경우에는 그 독성으로 인하여 꾸준한 복용이 어렵고 다른 질병을 발생시키는 문제점이 있었다. 따라서, 인체에 무해하면서도 꾸 준한 복용을 위해 종래에는 민간요법에 의해 전해지는 약재 및 재료로 이루어진 건강식품을 적당히 조리하여 음용하였다.Therefore, in order to strengthen the function of the prostate, it is effective to combine the medicine with a steady exercise therapy, in the case of both medicines due to its toxicity, it is difficult to take a steady and caused other diseases. Therefore, in order to continue taking harmless to the human body conventionally prepared by drinking a healthy food made of medicinal herbs and ingredients conveyed by folk medicine.
그러나, 이와 같이 민간요법에 의한 건강식품은 양약에 비하여 인체에 무해한 장점은 있으나, 정확한 성분비율에 맞추어 처방되지 않기 때문에 균일하고 정확한 약리 성분을 유지하는 것이 어려운 문제점이 발생되었다. 또한, 민간요법에 의한 건강식품은 대부분 탕제 방식으로 제조되므로 음용이 불편한 문제점이 발생되었다.However, the health food by folk remedies has the advantage of harmless to the human body as compared to medicinal herbs, but it is difficult to maintain a uniform and accurate pharmacological ingredients because it is not prescribed according to the correct ingredient ratio. In addition, since most of the health foods by folk remedies are prepared by the type of decoction, drinking is inconvenient.
뿐만 아니라, 민간요법에 의해 제조되는 건강식품은 전립선에 필요한 약리 성분 이외에 다른 성분들도 상당수 포함되므로 보다 빠르고 효과적인 약리 효과를 기대할 수 없는 문제점이 발생되었다.In addition, the health food manufactured by folk remedies includes a large number of other ingredients in addition to the pharmacological components required for the prostate, a problem that can not expect a faster and more effective pharmacological effect has occurred.
본 발명은 전술한 바와 같은 종래의 제반 문제점을 해결하기 위하여 안출된 것으로, 본 발명의 목적은 천연물질에서 전립선에 유익한 물질만을 추출하여 배합하므로 전립선에 지속적인 효과를 발휘할 수 있는 전립선을 위한 건강식품 제조방법을 제공하는데 있다.The present invention has been made to solve the conventional problems as described above, the object of the present invention is to extract only the substances beneficial to the prostate from the natural substance, and formulated health food for the prostate gland that can exert a continuous effect on the prostate gland To provide a method.
또한, 본 발명의 다른 목적은 추출된 물질들을 복용이 간편하고 대량 생산이 가능한 형태로 제조할 수 있는 전립선 및 방광을 위한 건강식품 제조방법을 제공하는데 있다.In addition, another object of the present invention to provide a health food manufacturing method for the prostate gland and bladder that can be produced in a form that is easy to take the extracted materials and mass production.
이와 같은 목적을 달성하기 위한 본 발명의 전립선을 위한 건강식품은 호박씨유 23~28중량%, 대두추출물 19~24중량%, 산화아연 0.004~0.01중량%, 쏘팔메토 41~51중량%, 달맞이꽃종자유 3~5중량%, 옥수수수염추출물 0.04~0.1중량%를 포함한다.Health food for the prostate of the present invention for achieving the above object is 23-28% by weight of pumpkin seed oil, 19-24% by weight of soybean extract, 0.004-0.01% by weight of zinc oxide, 41-51% by weight of saw palmetto, evening primrose It contains 3 to 5% by weight of seed oil and 0.04 to 0.1% by weight of corn beard extract.
본 발명의 전립선을 위한 건강식품 제조방법은 호박씨, 대두, 쏘팔메토, 달맞이꽃종자, 옥수수수염에서, 호박씨유, 대두추출물, 쏘팔메토, 달맞이꽃종자유, 옥수수수염추출물을 추출하는 추출단계와; 상기 추출단계에 의해 추출된 성분을 호박씨유 23~28중량%, 대두추출물 19~24중량%, 산화아연 0.004~0.01중량%, 쏘팔메토 41~51중량%, 달맞이꽃종자유 3~5중량%, 옥수수수염추출물 0.04~0.1중량%의 비율로 배합하는 배합단계와; 상기 배합단계에 의해 배합된 배합물을 일정한 크기의 조성물로 성형 제조하는 성형단계를 포함하는 것을 특징으로 한다.Health food manufacturing method for the prostate of the present invention is an extraction step of extracting pumpkin seed, soybean, saw palmetto, evening primrose seed, corn beard, pumpkin seed oil, soybean extract, saw palmetto, evening primrose oil, corn beard extract; Pumpkin seed oil extracted by the extraction step 23 ~ 28% by weight, soybean extract 19 ~ 24% by weight, zinc oxide 0.004 ~ 0.01% by weight, saw palmetto 41 ~ 51% by weight, evening primrose oil 3 ~ 5%, A blending step of blending the ratio of 0.04 to 0.1% by weight of the corn beard extract; It characterized in that it comprises a molding step of molding the formulation blended by the compounding step to a composition of a predetermined size.
이하, 본 발명을 보다 상세하게 설명하면 다음과 같다.Hereinafter, the present invention will be described in more detail.
도 1은 본 발명에 따른 제조방법을 개략적으로 나타낸 블록도로서, 본 발명의 전립선을 위한 건강식품 제조방법은 크게 추출단계와 배합단계 및 성형단계로 이루어진다.1 is a block diagram schematically showing a manufacturing method according to the present invention, the health food manufacturing method for the prostate of the present invention is largely composed of an extraction step, a compounding step and a molding step.
먼저, 추출단계는 전립선에 유용한 성분인 호박씨유, 대두추출물, 쏘팔메토, 달맞이꽃종자유, 옥수수수염 추출물을 추출하는 단계로서, 세부적으로 호박씨유 추 출단계, 대두추출물 추출단계, 쏘팔메토 추출단계, 달맞이꽃종자유 추출단계 그리고 옥수수수염물 추출단계로 이루어진다.First, the extraction step is to extract the pumpkin seed oil, soybean extract, saw palmetto, evening primrose seed oil, corn beard extract which are useful ingredients for the prostate, and in detail, the pumpkin seed oil extraction step, soybean extract extraction step, saw palmetto extraction step , Evening primrose seed extraction and corn salt extraction step.
호박씨유 추출단계는 호박씨에서 호박씨유를 추출하는 단계로서, 초임계 이산화탄소를 이용한 추출방법을 통해 호박씨유를 추출하게 된다. 여기서 초임계 이산화탄소를 이용한 추출방법을 간략하게 설명하면, 초임계란 일정한 용매가 특정 온도와 압력을 넘어서면 아무리 압력과 열을 가해도 액체나 기체가 되지 않는 상태를 말한다.Pumpkin seed oil extraction step is to extract the pumpkin seed oil from the pumpkin seeds, the pumpkin seed oil is extracted through the extraction method using supercritical carbon dioxide. Here, briefly explaining the extraction method using supercritical carbon dioxide, supercritical refers to a state in which a liquid or a gas does not become a liquid or a gas even if a certain solvent exceeds a certain temperature and pressure, no matter how much pressure and heat are applied.
이러한 초임계 용매는 기체와 액체의 장점을 함께 가지고 있기 때문에, 액체처럼 다른 물질을 쉽게 녹일 수 있으며, 기체와 같이 확산이 매우 뛰어나서 유용한 성분을 녹여낸 다음, 잔류 물질 없이 완전한 제거가 가능하다.Since these supercritical solvents have the advantages of gas and liquid, they can easily dissolve other substances like liquids, and are very diffuse, such as gases, to dissolve useful components and then remove them completely without any residue.
본 발명은 이러한 초임계의 특성을 이용하여 호박씨에서 호박씨유를 추출하며, 초임계 용매로는 이산화탄소를 사용하였다. 그 이유는 이산화탄소가 화학적 안정성이 뛰어나고, 부식성이 없으며, 인체에 대한 독성이 없기 때문이다. 또한, 임계온도가 실온근처 또는 추출온도에 가깝고, 낮은 임계압력, 큰 용해도, 쉬운 선택, 저렴한 구입비용 등의 여러 장점 때문에 이산화탄소를 초임계 용매로 사용하였다.The present invention extracts the pumpkin seed oil from the pumpkin seeds using the characteristics of the supercritical, carbon dioxide was used as the supercritical solvent. The reason is that carbon dioxide has excellent chemical stability, is not corrosive and nontoxic to humans. In addition, carbon dioxide was used as the supercritical solvent because of its advantages such as near the room temperature or near the extraction temperature, low critical pressure, large solubility, easy selection, low cost of purchase.
대두추출물추출단계는 대두에서 흰색 분말 형태의 대두추출물을 추출하는 단계로서, 본 발명에서는 에탄올을 이용한 추출방법을 통해 대두에서 대두추출물을 추출하게 된다. 여기서, 상기 에탄올을 이용한 추출방법을 간략하게 설명하면, 에탄올에 추출하고자 하는 물질(대두)을 잘게 부순 후 일정기간, 열과 빛을 동시에 차단할 수 있는 냉암소에 침적시켜 녹여내는 방법으로, 솔벤트법이라고도 한다.Soybean extract extraction step is to extract the soybean extract in the form of white powder from soybean, in the present invention is to extract the soybean extract from soybean through the extraction method using ethanol. Here, briefly explaining the extraction method using ethanol, a method of crushing the material (soybean) to be extracted in ethanol finely, and then melted by melting in a cool dark place that can block heat and light at the same time, also called a solvent method. do.
즉, 추출하고자 하는 물질을 농축하게 되면 왁스가 함유된 고형물질이 얻어지게 되고, 상기 고형물에 에탄올을 가하면 왁스는 녹지 않고 스테롤성분만 녹아 나오게 된다. 따라서, 녹아 나온 스테롤 성분을 여과 및 분쇄하게 됨으로써, 원하는 분말 형태의 추출물을 얻을 수 있는 것이다.That is, when the material to be extracted is concentrated, a solid material containing wax is obtained. When ethanol is added to the solid material, only the sterol component is dissolved without melting the wax. Therefore, by filtering and pulverizing the dissolved sterol component, it is possible to obtain an extract of the desired powder form.
쏘팔메토 추출단계는 해바라기씨, 마늘, 야자로 이루어진 혼합야채에서 해바라기씨유, 마늘유, 야자유로 이루어진 쏘팔메토를 추출하는 단계로서, 본 발명에서는 초임계 이산화탄소를 이용한 추출방법을 통해 쏘팔메토를 추출하게 된다. 이러한 초임계 이산화탄소를 이용한 추출방법은 호박씨유추출단계의 추출방법과 같다.Saw palmetto extraction step is to extract the saw palmetto consisting of sunflower seed oil, garlic oil, palm oil from a mixed vegetable consisting of sunflower seeds, garlic, palm, in the present invention, saw palmetto through the extraction method using supercritical carbon dioxide The soil will be extracted. The extraction method using the supercritical carbon dioxide is the same as the extraction method of the pumpkin seed oil extraction step.
달맞이꽃종자유 추출단계는 달맞이꽃종자에서 달맞이꽃종자유를 추출하는 단계로서, 본 발명에서는 저온추출방법(Cold pressed extraction)을 통해 달맞이꽃종자유를 추출하게 된다. 여기서, 상기 저온추출방법에 대해 간략하게 설명하면, 식품 원료(달맞이꽃종자)를 파쇄한 후, 파쇄된 물질들의 어는점 온도가 서로 상이한 점을 이용해 저온에서 파쇄된 물질들 각각을 분리 처리하여 원하는 추출물(달맞이꽃종자유)을 얻게 되는 것이다.Evening primrose seed oil extraction step is to extract the evening primrose seed oil from the evening primrose seed, in the present invention is to extract the evening primrose seed oil through a cold pressed extraction (Cold pressed extraction). Here, briefly explaining the low temperature extraction method, after crushing the food raw material (Evening Primrose Seeds), using a point where the freezing point temperature of the crushed material is different from each other by treating each of the crushed material at a low temperature to extract the desired extract ( Evening Primrose Oil) will be obtained.
이처럼, 저온추출방법을 이용하는 이유는 식품의 각종 유효 영양소가 파괴되는 것을 최소화시키기 위한 것으로, 고온 고압을 이용하여 추출하는 경우에는 식품을 장시간 동안 가열하기 때문에 항산화 작용과 식품의 각종 유효성분이 90%이상 파괴되며, 식품 고유의 색도 변하는 문제가 있다.As such, the reason for using the low temperature extraction method is to minimize the destruction of various effective nutrients of the food. When extracting using high temperature and high pressure, the food is heated for a long time, so the antioxidant activity and various active ingredients of the food are 90% or more. Destroyed, there is a problem that the color of the food changes.
옥수수수염물 추출단계는 옥수수수염에서 짙은 갈색 분말 형태의 옥수수수염 추출물을 추출하는 단계로서, 본 발명에서는 대두추출물 추출단계와 마찬가지로 에탄올 추출방법에 의해 옥수수수염 추출물을 추출하게 된다.Corn salt extraction step is a step of extracting the corn beard extract in the form of dark brown powder from the corn beard, in the present invention, the corn beard extract is extracted by the ethanol extraction method as the soybean extract extraction step.
한편, 배합단계는 상기한 추출단계를 통해 추출된 성분들을 소정의 비율로 배합하는 단계로서, 본 발명에서는 호박씨유 23~28중량%, 대두추출물 19~24중량%, 산화아연 0.004~0.01중량%, 쏘팔메토 41~51중량%, 달맞이꽃종자유 3~5중량%, 옥수수수염추출물 0.04~0.1중량%의 비율로 배합하였다.On the other hand, the blending step is a step of blending the components extracted through the extraction step in a predetermined ratio, in the present invention, 23 to 28% by weight of pumpkin seed oil, 19 to 24% by weight of soy extract, 0.004 to 0.01% by weight of zinc oxide , 41 ~ 51% by weight of saw palmetto, 3 ~ 5% by weight of evening primrose seed oil, corn beard extract in a ratio of 0.04 ~ 0.1% by weight.
성형단계는 배합단계를 통해 배합된 배합물을 일정한 크기의 조성물로 성형 제조하는 단계로서, 본 발명에서는 복용이 편리하도록 소정 크기의 캡슐이나 타블렛 또는 환(丸)형태로 성형 제조하게 된다.The molding step is a step of molding the blended compound through a compounding step into a composition of a certain size, in the present invention is to be molded and manufactured in the form of capsules, tablets or pills of a predetermined size for convenient taking.
이하, 본 발명에 따라 배합 및 제조된 조성물의 성분 특성을 상세하게 설명하면, 호박씨유(Pumpkin seed oil)는 예로부터 이뇨제, 신장병, 중풍예방에 효과가 있어 민간요법으로 널리 이용되어 왔다. 이러한 호박씨유는 불포화지방산, 단백질, 토코페롤, 탄수화물을 함유하고 있어, 특히 여러 가지 순환기계 성인병(비뇨기계, 심혈관계)에 효과가 있는 것으로 알려지고 있다.Hereinafter, the component properties of the composition blended and prepared according to the present invention in detail, pumpkin seed oil (Pumpkin seed oil) has been widely used as a folk remedy since it is effective in preventing diuretics, kidney disease, and stroke. These pumpkin seed oils contain unsaturated fatty acids, proteins, tocopherols and carbohydrates, and are known to be particularly effective for various circulatory adult diseases (urinary system, cardiovascular system).
일 예로 스웨덴 스톡홀름에 있는 Karolinska 비뇨기과 전문병원의 Carbin 등의 임상실험 결과에 따르면, 호박씨 기름성분인 phytosterol(beta-sitosterol)을 전립선 비대 질환을 앓고 있는 환자에게 투여하였을 때 뛰어난 치료효과를 나타내는 것으로 보고되었다(영국 비뇨학회지 발표).For example, according to a clinical test result of Carbin et al. Of Karolinska Urology Hospital in Stockholm, Sweden, phytosterol (beta-sitosterol), a pumpkin seed oil, has been reported to have an excellent therapeutic effect when administered to patients with an enlarged prostate disease. (Published by the British Journal of Urology).
또한, 독일에서는 호박씨 기름을 주원료로 하여 개발한 Prosta Fink Forte capsules을 경미한 전립선염 환자(2245명)에게 투여한 임상실험에서 약 46%의 개선효과가 나타난 것으로 보고되었다.In addition, in Germany, a clinical trial of Prosta Fink Forte capsules developed with pumpkin seed oil as a major ingredient in patients with mild prostatitis (2245 patients) reported an improvement of about 46%.
한편, 대두추출물은 대두에는 콜레스테롤 및 혈당을 저하시키고 독성물질을 체외로 배출하여 암발생을 억제하는 것으로 널리 알려져 있다. 특히, 콜레스테롤을 흡착, 장내 흡수를 저해하여 혈청지질을 감소시키는데 매우 뛰어난 효과가 있다. 따라서, 콜레스테롤 수치의 저하를 통해 전립선의 기능을 개선시키게 된다.On the other hand, soy extract is known to reduce the cholesterol and blood sugar in soybeans and to discharge cancer to the outside by inhibiting the development of cancer. In particular, it has a very excellent effect in reducing serum lipid by absorbing cholesterol, inhibiting intestinal absorption. Thus, lowering cholesterol levels improves the function of the prostate gland.
산화아연은 1996년 Annals of internal medicine 이라는 미국 내과학 논문에 약품으로는 처음으로 실릴 정도로 면역기능과 전립선 등의 향상에 탁월한 효과를 가진 미네랄이다. 이러한 산화아연은 인슐린의 구성분자이기도 하지만 에너지대사를 촉진하며, 비만해소와 전립선 비대증해소, 정력증진, 미각증진에 탁월한 효과가 있다.Zinc oxide is a mineral that has an excellent effect on the improvement of immune function and prostate, as it is the first drug published in the 1996 American journal of Internal Medicine. Although zinc oxide is a component of insulin, it promotes energy metabolism, and has an excellent effect on relieving obesity, relieving prostate hypertrophy, enhancing energy and taste.
쏘팔메토 (Saw Palmwtto)는 잎사귀의 모양이 톱 모양을 닮았다고 쏘팔메토라 부르며 이 쏘팔메토 나무의 크기는 대략 1.8~3m 이며 여기에서 열리는 열매의 크기는 길이가 1~2.5cm 이고 지름은 약 1cm 이다. 약간 길쭉한 올리브처럼 생긴 열매가 작은 방울들이 여러 개씩 뭉쳐있는 다발 모양으로 초기에는 초록색의 색깔이 익으면 짙은 밤색 또는 짙은 군청색의 색깔을 띤다. 수확시기는 가을에 하며 잘 전조하여 분말로 만들어서 차로 마시기도 하고 액체 이산화탄소에 의한 초임계추출(SFE CO2) 기술을 이용하여 분말 혹은 기름상태로 대부분 대체의학원료로 사용한다. 구성물질은 주로 지방산(약 94.04%)으로 포화지방산 55.76%, 불포화지방산 38.28%, Fatty alcohols 0.20% 그리고 식물성스테롤(Plant sterols 혹은 Phytosterols) 0.287% 등으로 구성되었는데 본 발명에서 중요한 물질은 식물성 스테롤이다. 1983년 Boccafoschi et al.은 320mg/day의 쏘팔메토를 8.5주 동안 22명의 환자에게 무작위임상시험, 이중맹검법, 위약 대조군의 시험을 통하여 위약 보다는 요속 개선과 야뇨증이 개선되었다． Emili et al.은 320 mg/day의 쏘팔메토를 4주 동안 30명의 BPH 환자에게 무작위, 이중맹검법, 위약대조군의 임상시험을 통하여 위약 보다는 요속이 호전되었다. 1985년 Cukier et al.은 320 mg/day의 쏘팔메토를 8.5주 동안 168명의 환자에게 무작위임상시험, 이중맹검법, 위약 대조군의 시험을 통하여 위약 보다는 잔뇨감과 야뇨증이 개선되었다.Saw Palmwtto is called Saw Palmetto, whose leaves resemble saws. The size of this saw palmetto tree is approximately 1.8 to 3 meters, and the fruit is about 1 to 2.5 cm in length and about diameter. 1 cm. It is a bunch of small droplets of fruit that looks like a little elongated olives. It is dark brown or deep navy blue when the green color is ripe. The harvest season is in the fall, and it is well prepared, made into powder, drunk as tea, and used as alternative medicine raw material in powder or oil state using supercritical extraction (SFE CO 2 ) technology by liquid carbon dioxide. The constituents were mainly fatty acids (about 94.04%), composed of 55.76% saturated fatty acids, 38.28% unsaturated fatty acids, 0.20% Fatty alcohols, and 0.287% vegetable sterols (Plant sterols or Phytosterols). In 1983, Boccafoschi et al. Improved urinary tract and nocturnal enuresis over placebo in a randomized trial, double-blind, or placebo-controlled trial with 320 mg / day saw palmetto for 8.5 weeks in 22 patients. Emili et al. Performed 320 mg / day saw palmetto over four weeks for 30 BPH patients in a randomized, double-blind, placebo-controlled trial that improved speed rather than placebo. In 1985, Cukier et al. Improved urinary sensation and nocturia rather than placebo in a randomized trial, double-blind, placebo-controlled trial of 320 mg / day saw palmetto for 8.5 weeks in 168 patients.
달맞이꽃종자유는 리놀레산(Linolenic acid)과 천연의 감마리놀렌산(Υ-Linolenicacid)이란 프로스타글란딘의 전구 물질을 함유하고 있으며, 이 물질은 전립선과 방광과 같은 성인병의 예방과 치료에 탁월한 효과를 나타내는 것으로 알려져 있다.Evening primrose oil contains linoleic acid and a natural precursor of prostaglandins, `` Linolenic acid '', which is known to have an excellent effect in the prevention and treatment of adult diseases such as the prostate and bladder.
옥수수수염 추출물은 예로부터 소변을 잘 나가게 하고, 열을 내리며, 얼굴로 치밀어 오르는 열기를 내려주는 것으로 널리 알려져 있다. 또한, 이뇨 · 소염 · 혈압강하 · 지혈 작용 등이 있어서 부종 · 신장염증 · 요도염 · 담낭담도염 · 방광결석 · 담석증 등에 탁월한 효과가 있다.Corn beard extract has been widely known for its ability to urinate well, lower heat, and lower the heat of the face. In addition, diuretic, anti-inflammatory, lowering blood pressure, hemostatic action, etc., is excellent in edema, nephritis, urethritis, cholecystitis, bladder stones, cholelithiasis.
이와 같이 본 발명은 전립선 및 방광에 탁월한 효과가 있는 여러 천연물질을 초임계 이산화탄소와 에탄올 및 저온추출방식을 이용한 추출단계를 통해 전립선과 방광에 유용한 성분만을 추출하였다. 그리고 추출된 성분은 배합단계를 통해 상기 한 비율로 배합하고, 성형단계를 통해 캡슐 및 타블렛 또는 환(丸)형태로 생산하므로 지속적인 효과와 복용이 간편한 것이다.As such, the present invention extracts only the components useful for the prostate and the bladder through the extraction step using supercritical carbon dioxide, ethanol and low temperature extraction of various natural substances having excellent effects on the prostate and bladder. And the extracted components are blended in the above ratio through the compounding step, and produced in capsule and tablet or pill form through the molding step is a continuous effect and easy to take.
이상에서와 같이 본 발명은 전립선 및 방광에 탁월한 효과가 있는 여러 천연물질을 추출단계를 통해 유용한 성분만을 추출하므로 종래의 민간요법과는 달리 전립선과 방광기능에 불필요한 다른 성분이 거의 포함되지 않는다. 따라서, 보다 빠르고 직접적인 전립선과 방광의 개선 효과를 얻을 수 있는 효과가 있다.As described above, the present invention extracts only useful components through the extraction step of various natural substances having excellent effects on the prostate and bladder, unlike conventional folk remedies, almost no other components unnecessary for prostate and bladder function. Therefore, there is an effect that can obtain a faster and more direct improvement of the prostate and bladder.
또한, 본 발명은 배합단계를 통해 소정의 비율로 배합되므로 항상 일정한 약리 성분의 비율을 유지하게 된다. 따라서, 전립선과 방광의 지속적인 기능 향상을 가져올 수 있는 효과가 있다.In addition, since the present invention is formulated at a predetermined ratio through the compounding step, it always maintains a constant ratio of pharmacological components. Therefore, there is an effect that can bring continuous improvement of the prostate and bladder.
더욱이, 본 발명은 성형단계를 통해 캡슐이나 타블렛 또는 환(丸)형태로 생산되므로 어디서나 자유롭게 섭취 가능한 매우 유용한 효과와 함께 대량 생산도 가능한 효과도 있는 것이다.Furthermore, the present invention is produced in the form of capsules, tablets or pills through the molding step, so that there is also a very useful effect that can be freely consumed anywhere, as well as mass production.
이하, 실시예는 오로지 본 발명을 보다 구체적으로 설명하기 위한 것으로서, 본 발명의 요지에 따라 본 발명의 범위가 이들 실시예에 의해 제한되지 않는다는 것은 본 발명이 속하는 기술분야에서 통상의 지식을 가진 자에게 있어서 자명할 것이다.Hereinafter, the examples are only for illustrating the present invention in more detail, and the scope of the present invention is not limited by these examples in accordance with the gist of the present invention, those skilled in the art. Will be self-evident.
실시예 1: 추출단계Example 1 Extraction Step
호박씨, 대두, 쏘팔메토, 달맞이꽃종자, 옥수수수염에서 호박씨유, 대두추출물, 쏘팔메토, 달맞이꽃종자유, 옥수수수염추출물을 추출하였다.Pumpkin seed oil, soybean extract, saw palmetto, evening primrose oil, corn beard extract were extracted from pumpkin seed, soybean, saw palmetto, evening primrose seed, and corn beard.
실시예 2: 배합단계Example 2: Compounding Step
상기 추출된 성분을 단위 중량당 호박씨유 23~28중량%, 대두추출물 19~24중량%, 산화아연 0.004~0.01중량%, 쏘팔메토 41~51중량%, 달맞이꽃종자유 3~5중량%, 옥수수수염추출물 0.04~0.1중량%의 비율로 배합하였다.Pumpkin seed oil 23 to 28% by weight, soybean extract 19 ~ 24% by weight, zinc oxide 0.004 ~ 0.01% by weight, saw palmetto 41 ~ 51% by weight, evening primrose oil 3 ~ 5%, corn Beard extract was blended at a ratio of 0.04 to 0.1% by weight.
실시예 3: 성형단계Example 3: Molding Step
상기 배합된 배합물을 하드캡슐, 소프트캡슐 또는 타블렛 형태로 성형 제조하였다.The blended formulations were molded and prepared in the form of hard capsules, soft capsules or tablets.
도 1은 본 발명에 따른 제조방법을 개략적으로 나타낸 블록도이다.1 is a block diagram schematically showing a manufacturing method according to the present invention.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102614295A (en) * | 2012-03-15 | 2012-08-01 | 黄宏植 | Food therapy product for protecting prostate and preparation method for food therapy product |
| KR101350593B1 (en) * | 2012-02-22 | 2014-01-14 | 우석대학교 산학협력단 | Method for manufacturing combined preparations containing saw palmetto and zinc sulfate |
| CN112450285A (en) * | 2020-10-21 | 2021-03-09 | 武汉轻工大学 | Oxidation-resistant pumpkin seed oil capsule and preparation method thereof |
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| KR101350593B1 (en) * | 2012-02-22 | 2014-01-14 | 우석대학교 산학협력단 | Method for manufacturing combined preparations containing saw palmetto and zinc sulfate |
| CN102614295A (en) * | 2012-03-15 | 2012-08-01 | 黄宏植 | Food therapy product for protecting prostate and preparation method for food therapy product |
| CN112450285A (en) * | 2020-10-21 | 2021-03-09 | 武汉轻工大学 | Oxidation-resistant pumpkin seed oil capsule and preparation method thereof |
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