KR20100092463A - Ｍｃｐ-1 결합형 핵산 및 이의 용도 - Google Patents

Ｍｃｐ-1 결합형 핵산 및 이의 용도 Download PDF

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Publication number
KR20100092463A
KR20100092463A KR1020107011757A KR20107011757A KR20100092463A KR 20100092463 A KR20100092463 A KR 20100092463A KR 1020107011757 A KR1020107011757 A KR 1020107011757A KR 20107011757 A KR20107011757 A KR 20107011757A KR 20100092463 A KR20100092463 A KR 20100092463A
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KR
South Korea
Prior art keywords
stretch box
nucleotide sequence
nucleic acid
chronic
mcp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020107011757A
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English (en)
Korean (ko)
Inventor
웨르너르 퍼르쉬케이
플로리안 야로슈
디르크 율베르그
스벤 클루스만
클라우스 부크너르
크리스티안 매쉬
Original Assignee
녹손 파르마 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 녹손 파르마 아게 filed Critical 녹손 파르마 아게
Publication of KR20100092463A publication Critical patent/KR20100092463A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/30—Special therapeutic applications

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020107011757A 2007-11-30 2008-11-29 Ｍｃｐ-1 결합형 핵산 및 이의 용도 Ceased KR20100092463A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07023267.3 2007-11-30
EP07023267 2007-11-30

Publications (1)

Publication Number Publication Date
KR20100092463A true KR20100092463A (ko) 2010-08-20

Family

ID=40415282

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107011757A Ceased KR20100092463A (ko) 2007-11-30 2008-11-29 Ｍｃｐ-1 결합형 핵산 및 이의 용도

Country Status (12)

Country Link
US (2) US20100311816A1 (https=)
EP (1) EP2229442A1 (https=)
JP (1) JP5777341B2 (https=)
KR (1) KR20100092463A (https=)
CN (1) CN101878305A (https=)
AU (1) AU2008329070B2 (https=)
BR (1) BRPI0819845A2 (https=)
CA (1) CA2707089A1 (https=)
MX (1) MX2010005916A (https=)
RU (1) RU2542973C2 (https=)
WO (1) WO2009068318A1 (https=)
ZA (1) ZA201002974B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8193159B2 (en) 2006-02-14 2012-06-05 Noxxon Pharma Ag MCP-1 binding nucleic acids
US20100311816A1 (en) * 2007-11-30 2010-12-09 Noxxon Pharma Ag MCP-1 binding nucleic acids and use thereof
WO2012025251A1 (en) 2010-08-27 2012-03-01 Noxxon Pharma Ag Nucleic acids for treatment of chronic complications of diabetes
CN102621331B (zh) * 2012-04-05 2014-07-30 中国医学科学院病原生物学研究所 一种检测或辅助检测结核性胸膜炎的试剂盒
JP2017502075A (ja) * 2013-11-04 2017-01-19 ノクソン ファーマ エージー 腎障害治療の手段および方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6670321B1 (en) * 1998-12-30 2003-12-30 The Children's Medical Center Corporation Prevention and treatment for retinal ischemia and edema
WO2002081628A2 (en) * 2001-04-05 2002-10-17 Ribozyme Pharmaceuticals, Incorporated Modulation of gene expression associated with inflammation proliferation and neurite outgrowth, using nucleic acid based technologies
US7629456B2 (en) * 2001-10-26 2009-12-08 Noxxon Pharma Ag Modified L-nucleic acid
US7879991B2 (en) * 2002-05-06 2011-02-01 Noxxon Pharma Ag CGRP binding nucleic acids
US7750140B2 (en) * 2002-08-01 2010-07-06 Noxxon Pharma Ag Ghrelin binding nucleic acids
KR20060003353A (ko) * 2003-04-15 2006-01-10 머크 앤드 캄파니 인코포레이티드 케모킨 수용체의벤족사지닐-아미도사이클로펜틸-헤테로사이클릭 조절제
EP1732571A4 (en) * 2004-03-05 2009-09-09 Archemix Corp CONTROLLED MODULATION OF PHARMACOKINETICS AND BIODISTRIBUTION OF APTAMER THERAPEUTICS
US20060257359A1 (en) * 2005-02-28 2006-11-16 Cedric Francois Modifying macrophage phenotype for treatment of disease
US8367629B2 (en) * 2006-02-14 2013-02-05 Noxxon Pharma Ag MCP-1 binding nucleic acids and use thereof
US8193159B2 (en) * 2006-02-14 2012-06-05 Noxxon Pharma Ag MCP-1 binding nucleic acids
US20100311816A1 (en) * 2007-11-30 2010-12-09 Noxxon Pharma Ag MCP-1 binding nucleic acids and use thereof

Also Published As

Publication number Publication date
US20100311816A1 (en) 2010-12-09
WO2009068318A1 (en) 2009-06-04
CA2707089A1 (en) 2009-06-04
JP2011504736A (ja) 2011-02-17
CN101878305A (zh) 2010-11-03
BRPI0819845A2 (pt) 2015-06-16
AU2008329070A1 (en) 2009-06-04
US20150141496A1 (en) 2015-05-21
RU2542973C2 (ru) 2015-02-27
JP5777341B2 (ja) 2015-09-09
MX2010005916A (es) 2010-06-11
RU2010126662A (ru) 2012-01-10
AU2008329070B2 (en) 2014-11-20
EP2229442A1 (en) 2010-09-22
ZA201002974B (en) 2011-07-27

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Patent event date: 20100528

Patent event code: PA01051R01D

Comment text: International Patent Application

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PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20131127

Comment text: Request for Examination of Application

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Comment text: Notification of reason for refusal

Patent event date: 20150821

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20160719

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20150821

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I