KR20100053607A - 항-ｔｗｅａｋ 수용체 항체의 치료 용도 - Google Patents
항-ｔｗｅａｋ 수용체 항체의 치료 용도 Download PDFInfo
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- KR20100053607A KR20100053607A KR1020107004817A KR20107004817A KR20100053607A KR 20100053607 A KR20100053607 A KR 20100053607A KR 1020107004817 A KR1020107004817 A KR 1020107004817A KR 20107004817 A KR20107004817 A KR 20107004817A KR 20100053607 A KR20100053607 A KR 20100053607A
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95374507P | 2007-08-03 | 2007-08-03 | |
| US60/953,745 | 2007-08-03 | ||
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| ES2363669B1 (es) * | 2009-06-10 | 2012-08-09 | Fundacio Privada Institut D'investigacio Biomedica De Bellvitge (Idibell) | Metodo para determinar el riesgo de desarrollar metastasis cerebral y un kit para llevar a cabo dicho procedimiento |
| CN102675460B (zh) * | 2011-02-28 | 2015-08-19 | 珠海市丽珠单抗生物技术有限公司 | 抗肿瘤坏死因子α的人源化抗体 |
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| AU2014203658B2 (en) * | 2011-08-23 | 2016-04-28 | La Trobe University | FN14 binding proteins and uses thereof |
| WO2013026099A1 (en) | 2011-08-23 | 2013-02-28 | Transbio Ltd | Fn14 binding proteins and uses thereof |
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| AU2013280644B2 (en) | 2012-06-26 | 2018-08-02 | Jeffrey A. BACHA | Methods for treating tyrosine-kinase-inhibitor-resistant malignancies in patients with genetic polymorphisms or AHI1 dysregulations or mutations employing dianhydrogalactitol, diacetyldianhydrogalactitol, dibromodulcitol, or analogs or derivatives thereof |
| NO2760138T3 (enExample) | 2012-10-01 | 2018-08-04 | ||
| JP2016519684A (ja) | 2013-04-08 | 2016-07-07 | デニス エム ブラウン | 準最適に投与された薬物療法の有効性を改善するための及び／又は副作用を低減するための方法および組成物 |
| MX2015016814A (es) | 2013-06-14 | 2016-08-08 | Bayer Pharma AG | Anticuerpo anti-tweakr y sus usos. |
| US9238034B2 (en) * | 2013-07-09 | 2016-01-19 | The Translational Genomics Research Institute | FN14 antagonists and therapeutic uses thereof |
| US9797882B2 (en) | 2013-07-09 | 2017-10-24 | The Translational Genomics Research Institute | Method of screening for a compound for inhibitory activity of FN14-tweak interaction |
| JP6721507B2 (ja) | 2013-12-23 | 2020-07-15 | バイエル・ファルマ・アクティエンゲゼルシャフト | Ｋｓｐ阻害剤との抗体薬物複合体（ａｄｃ） |
| WO2016061632A1 (en) * | 2014-10-23 | 2016-04-28 | La Trobe University | Fn14-binding proteins and uses thereof |
| CA2970565A1 (en) * | 2014-12-15 | 2016-06-23 | Bayer Pharma Aktiengesellschaft | Antibody-drug conjugates (adcs) of ksp inhibitors with aglycosylated anti-tweakr antibodies |
| SG10201908685QA (en) * | 2015-06-22 | 2019-10-30 | Bayer Pharma AG | Antibody drug conjugates (adcs) and antibody prodrug conjugates (apdcs) with enzymatically cleavable groups |
| JP2018525334A (ja) | 2015-06-23 | 2018-09-06 | バイエル ファーマ アクチエンゲゼルシャフト | キネシンスピンドルタンパク質（ｋｓｐ）阻害剤の抗ｔｗｅａｋｒ抗体との抗体薬物複合体 |
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| WO2017060322A2 (en) | 2015-10-10 | 2017-04-13 | Bayer Pharma Aktiengesellschaft | Ptefb-inhibitor-adc |
| AU2017236431A1 (en) | 2016-03-24 | 2018-09-27 | Bayer Pharma Aktiengesellschaft | Prodrugs of cytotoxic active agents having enzymatically cleavable groups |
| CA3027445A1 (en) | 2016-06-15 | 2017-12-21 | Bayer Pharma Aktiengesellschaft | Specific antibody-drug-conjugates (adcs) with ksp inhibitors and anti-cd123-antibodies |
| EP3558386A1 (de) | 2016-12-21 | 2019-10-30 | Bayer Aktiengesellschaft | Prodrugs von cytotoxischen wirkstoffen mit enzymatisch spaltbaren gruppen |
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| MX2019007641A (es) | 2016-12-21 | 2019-09-09 | Bayer Pharma AG | Conjugados de ligando-farmaco (adcs) con grupos escindibles enzimaticamente. |
| WO2019149637A1 (en) | 2018-01-31 | 2019-08-08 | Bayer Aktiengesellschaft | Antibody drug conjugates (adcs) with nampt inhibitors |
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| JP7415939B2 (ja) * | 2018-10-31 | 2024-01-17 | アステラス製薬株式会社 | 抗ヒトＦｎ１４抗体 |
| WO2021013693A1 (en) | 2019-07-23 | 2021-01-28 | Bayer Pharma Aktiengesellschaft | Antibody drug conjugates (adcs) with nampt inhibitors |
| WO2024105206A1 (en) | 2022-11-17 | 2024-05-23 | Vincerx Pharma Gmbh | Antibody-drug-conjugates cleavable in a tumor microenvironment |
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| MX2010001378A (es) | 2010-06-02 |
| AU2008284025A1 (en) | 2009-02-12 |
| JP2010535713A (ja) | 2010-11-25 |
| EP2182982A2 (en) | 2010-05-12 |
| BRPI0814768A2 (pt) | 2015-03-03 |
| CA2694751C (en) | 2015-07-14 |
| AU2008284025A2 (en) | 2010-04-01 |
| EP2182982B1 (en) | 2013-03-27 |
| NZ582815A (en) | 2012-07-27 |
| CN102006886A (zh) | 2011-04-06 |
| EP2545938A1 (en) | 2013-01-16 |
| WO2009020933A3 (en) | 2009-03-26 |
| WO2009020933A2 (en) | 2009-02-12 |
| US20090074762A1 (en) | 2009-03-19 |
| US9056908B2 (en) | 2015-06-16 |
| JP5409628B2 (ja) | 2014-02-05 |
| ES2411907T8 (es) | 2013-08-30 |
| CA2694751A1 (en) | 2009-02-12 |
| WO2009020933A9 (en) | 2009-07-09 |
| IL203038A (en) | 2014-03-31 |
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