KR20070037441A - 1,4 ｏ-결합된 사카로즈 유도체를 하나 이상 함유하는 분무건조된 분말 및 이의 제조방법 - Google Patents

1,4 ｏ-결합된 사카로즈 유도체를 하나 이상 함유하는 분무건조된 분말 및 이의 제조방법 Download PDF

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Publication number
KR20070037441A
KR20070037441A KR1020067025973A KR20067025973A KR20070037441A KR 20070037441 A KR20070037441 A KR 20070037441A KR 1020067025973 A KR1020067025973 A KR 1020067025973A KR 20067025973 A KR20067025973 A KR 20067025973A KR 20070037441 A KR20070037441 A KR 20070037441A
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KR
South Korea
Prior art keywords
powder
spray dried
linked
fraction
dried powder
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KR1020067025973A
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English (en)
Korean (ko)
Inventor
리하르트 푸르헤르
슈테판 바싸랍
카롤리네 베흐톨트-페터스
볼프강 프리쓰
파트릭크 가리델
토르스텐 슐츠-파뎀레흐트
Original Assignee
베링거 잉겔하임 파르마 게엠베하 운트 코 카게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 베링거 잉겔하임 파르마 게엠베하 운트 코 카게 filed Critical 베링거 잉겔하임 파르마 게엠베하 운트 코 카게
Publication of KR20070037441A publication Critical patent/KR20070037441A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
KR1020067025973A 2004-05-10 2005-05-04 1,4 ｏ-결합된 사카로즈 유도체를 하나 이상 함유하는 분무건조된 분말 및 이의 제조방법 KR20070037441A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004022926.0 2004-05-10
DE102004022926A DE102004022926A1 (de) 2004-05-10 2004-05-10 Sprühgetrocknete Pulver enthaltend zumindest ein 1,4 O-verknüpftes Saccharose-Derivat und Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
KR20070037441A true KR20070037441A (ko) 2007-04-04

Family

ID=34966513

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067025973A KR20070037441A (ko) 2004-05-10 2005-05-04 1,4 ｏ-결합된 사카로즈 유도체를 하나 이상 함유하는 분무건조된 분말 및 이의 제조방법

Country Status (7)

Country Link
EP (1) EP1778188A1 (de)
JP (1) JP2007536313A (de)
KR (1) KR20070037441A (de)
CA (1) CA2564324A1 (de)
DE (1) DE102004022926A1 (de)
TW (1) TW200605917A (de)
WO (1) WO2005112892A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7611709B2 (en) 2004-05-10 2009-11-03 Boehringer Ingelheim Pharma Gmbh And Co. Kg 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
WO2007072869A1 (ja) * 2005-12-21 2007-06-28 Eisai R & D Management Co., Ltd. １，２－ジヒドロピリジン化合物の非晶質体
EP2077132A1 (de) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung, Aufbewahrungsvorrichtung und Verfahren zur Abgabe einer Formulierung
CA2744655A1 (en) * 2008-11-27 2010-06-03 Boehringer Ingelheim International Gmbh Novel powdered crystalline medicines for inhalation
EP2662472B1 (de) 2009-03-31 2019-02-27 Boehringer Ingelheim International Gmbh Verfahren zur Beschichtung einer Oberfläche eines Bauteils
US9265910B2 (en) 2009-05-18 2016-02-23 Boehringer Ingelheim International Gmbh Adapter, inhalation device, and nebulizer
JP5658268B2 (ja) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
EP2504052B1 (de) 2009-11-25 2022-07-27 Boehringer Ingelheim International GmbH Zerstäuber
EP2585151B1 (de) 2010-06-24 2018-04-04 Boehringer Ingelheim International GmbH Vernebler
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
EP3030298B1 (de) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Vernebler
ES2954961T3 (es) 2014-05-07 2023-11-27 Boehringer Ingelheim Int Unidad, nebulizador y método
DK3139984T3 (da) 2014-05-07 2021-07-19 Boehringer Ingelheim Int Forstøver
RS64124B1 (sr) 2014-05-07 2023-05-31 Boehringer Ingelheim Int Inhalator i kontejner
BR112017008923A2 (pt) 2014-10-31 2017-12-26 Glaxosmithkline Ip Dev Ltd ?formulação em pó?

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5012272A (de) * 1973-06-01 1975-02-07
KR0161531B1 (ko) * 1990-03-08 1998-11-16 하야시바라 겐 락토수크로오스 고함유 분말의 제조방법과 그 분말의 용도
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
JPH0776527A (ja) * 1993-06-28 1995-03-20 Hayashibara Biochem Lab Inc 半固形製剤とその製造方法
ATE253899T1 (de) * 1994-01-31 2003-11-15 Yamanouchi Pharma Co Ltd Intraoral löslicher formpressling und verfahren zu seiner herstellung
US6051256A (en) * 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
US5955448A (en) * 1994-08-19 1999-09-21 Quadrant Holdings Cambridge Limited Method for stabilization of biological substances during drying and subsequent storage and compositions thereof
US5922324A (en) * 1995-01-31 1999-07-13 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Propolis extract with improved water-solubility
US5892026A (en) * 1995-04-12 1999-04-06 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo High Trehalose content syrup
US6258341B1 (en) * 1995-04-14 2001-07-10 Inhale Therapeutic Systems, Inc. Stable glassy state powder formulations
DE19732351A1 (de) * 1997-07-28 1999-02-04 Hoechst Ag Verfahren zur Herstellung der Süßkraft und zur Geschmacksverbesserung einer Mischung hochintensiver Süßstoffe
WO2002055101A2 (en) * 2000-12-21 2002-07-18 Inhale Therapeutic Syst Storage stable powder compositions of interleukin-4 receptor

Also Published As

Publication number Publication date
TW200605917A (en) 2006-02-16
DE102004022926A1 (de) 2005-12-15
JP2007536313A (ja) 2007-12-13
WO2005112892A1 (de) 2005-12-01
EP1778188A1 (de) 2007-05-02
CA2564324A1 (en) 2005-12-01

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