KR20060080376A - Cosmetic composition containing inorganic mineral solution and plant extract and preparation method thereof - Google Patents
Cosmetic composition containing inorganic mineral solution and plant extract and preparation method thereof Download PDFInfo
- Publication number
- KR20060080376A KR20060080376A KR1020050000751A KR20050000751A KR20060080376A KR 20060080376 A KR20060080376 A KR 20060080376A KR 1020050000751 A KR1020050000751 A KR 1020050000751A KR 20050000751 A KR20050000751 A KR 20050000751A KR 20060080376 A KR20060080376 A KR 20060080376A
- Authority
- KR
- South Korea
- Prior art keywords
- solution
- water
- skin
- cosmetic composition
- mineral
- Prior art date
Links
- 229910052500 inorganic mineral Inorganic materials 0.000 title claims abstract description 69
- 239000000203 mixture Substances 0.000 title claims abstract description 64
- 239000002537 cosmetic Substances 0.000 title claims abstract description 49
- 239000000419 plant extract Substances 0.000 title claims abstract description 20
- 238000002360 preparation method Methods 0.000 title description 9
- 239000011707 mineral Substances 0.000 claims abstract description 65
- 238000004090 dissolution Methods 0.000 claims abstract description 14
- 239000004615 ingredient Substances 0.000 claims abstract description 10
- 239000000243 solution Substances 0.000 claims description 81
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 62
- 229910052613 tourmaline Inorganic materials 0.000 claims description 34
- 239000011032 tourmaline Substances 0.000 claims description 34
- 229940070527 tourmaline Drugs 0.000 claims description 34
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 33
- 239000000284 extract Substances 0.000 claims description 26
- 238000000605 extraction Methods 0.000 claims description 26
- 239000010457 zeolite Substances 0.000 claims description 22
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 21
- 229910021536 Zeolite Inorganic materials 0.000 claims description 20
- 239000007788 liquid Substances 0.000 claims description 16
- 239000003960 organic solvent Substances 0.000 claims description 16
- 240000004922 Vigna radiata Species 0.000 claims description 15
- 235000010721 Vigna radiata var radiata Nutrition 0.000 claims description 15
- 240000008067 Cucumis sativus Species 0.000 claims description 14
- 235000011469 Vigna radiata var sublobata Nutrition 0.000 claims description 13
- 239000000843 powder Substances 0.000 claims description 13
- 239000000047 product Substances 0.000 claims description 13
- 238000002156 mixing Methods 0.000 claims description 12
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 claims description 11
- 238000003756 stirring Methods 0.000 claims description 11
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 10
- 239000004115 Sodium Silicate Substances 0.000 claims description 10
- 210000003056 antler Anatomy 0.000 claims description 10
- 159000000014 iron salts Chemical class 0.000 claims description 10
- 229910052911 sodium silicate Inorganic materials 0.000 claims description 10
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 claims description 9
- 244000194101 Ginkgo biloba Species 0.000 claims description 9
- 235000008100 Ginkgo biloba Nutrition 0.000 claims description 9
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims description 9
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 9
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims description 9
- 235000008422 Schisandra chinensis Nutrition 0.000 claims description 9
- 240000006079 Schisandra chinensis Species 0.000 claims description 9
- 229940010454 licorice Drugs 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 9
- 239000001508 potassium citrate Substances 0.000 claims description 9
- 229960002635 potassium citrate Drugs 0.000 claims description 9
- QEEAPRPFLLJWCF-UHFFFAOYSA-K potassium citrate (anhydrous) Chemical compound [K+].[K+].[K+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QEEAPRPFLLJWCF-UHFFFAOYSA-K 0.000 claims description 9
- 235000011082 potassium citrates Nutrition 0.000 claims description 9
- 241000196324 Embryophyta Species 0.000 claims description 8
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims description 8
- 240000008397 Ganoderma lucidum Species 0.000 claims description 8
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 8
- 229910021538 borax Inorganic materials 0.000 claims description 8
- 150000003839 salts Chemical class 0.000 claims description 8
- 239000004328 sodium tetraborate Substances 0.000 claims description 8
- 235000010339 sodium tetraborate Nutrition 0.000 claims description 8
- 244000303040 Glycyrrhiza glabra Species 0.000 claims description 7
- 241000282994 Cervidae Species 0.000 claims description 6
- 240000002045 Guettarda speciosa Species 0.000 claims description 6
- 235000001287 Guettarda speciosa Nutrition 0.000 claims description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 6
- 240000007594 Oryza sativa Species 0.000 claims description 6
- 235000007164 Oryza sativa Nutrition 0.000 claims description 6
- 239000004927 clay Substances 0.000 claims description 6
- -1 elvan Substances 0.000 claims description 6
- 235000009566 rice Nutrition 0.000 claims description 6
- 235000009849 Cucumis sativus Nutrition 0.000 claims description 5
- 239000004480 active ingredient Substances 0.000 claims description 5
- 239000007864 aqueous solution Substances 0.000 claims description 5
- 239000011888 foil Substances 0.000 claims description 5
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 4
- 235000017491 Bambusa tulda Nutrition 0.000 claims description 4
- 241001474374 Blennius Species 0.000 claims description 4
- 239000005909 Kieselgur Substances 0.000 claims description 4
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims description 4
- 240000001439 Opuntia Species 0.000 claims description 4
- 235000013389 Opuntia humifusa var. humifusa Nutrition 0.000 claims description 4
- 244000082204 Phyllostachys viridis Species 0.000 claims description 4
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 4
- WYTGDNHDOZPMIW-RCBQFDQVSA-N alstonine Natural products C1=CC2=C3C=CC=CC3=NC2=C2N1C[C@H]1[C@H](C)OC=C(C(=O)OC)[C@H]1C2 WYTGDNHDOZPMIW-RCBQFDQVSA-N 0.000 claims description 4
- 239000011425 bamboo Substances 0.000 claims description 4
- 239000000440 bentonite Substances 0.000 claims description 4
- 229910000278 bentonite Inorganic materials 0.000 claims description 4
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 claims description 4
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 4
- 229910052892 hornblende Inorganic materials 0.000 claims description 4
- 150000002505 iron Chemical class 0.000 claims description 4
- 230000002829 reductive effect Effects 0.000 claims description 4
- 235000013311 vegetables Nutrition 0.000 claims description 4
- 241001632410 Eleutherococcus senticosus Species 0.000 claims description 3
- 241001222097 Xenocypris argentea Species 0.000 claims description 3
- 230000004913 activation Effects 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 241000512259 Ascophyllum nodosum Species 0.000 claims description 2
- 239000005708 Sodium hypochlorite Substances 0.000 claims description 2
- 125000004432 carbon atom Chemical group C* 0.000 claims description 2
- 239000003054 catalyst Substances 0.000 claims description 2
- 239000003610 charcoal Substances 0.000 claims description 2
- 239000003657 drainage water Substances 0.000 claims description 2
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 claims description 2
- 239000013589 supplement Substances 0.000 claims description 2
- 244000170916 Paeonia officinalis Species 0.000 claims 2
- USHAGKDGDHPEEY-UHFFFAOYSA-L potassium persulfate Chemical compound [K+].[K+].[O-]S(=O)(=O)OOS([O-])(=O)=O USHAGKDGDHPEEY-UHFFFAOYSA-L 0.000 claims 1
- 230000003020 moisturizing effect Effects 0.000 abstract description 14
- 230000002087 whitening effect Effects 0.000 abstract description 14
- 230000000694 effects Effects 0.000 abstract description 13
- 230000007794 irritation Effects 0.000 abstract description 8
- 150000001450 anions Chemical class 0.000 abstract description 7
- 238000004519 manufacturing process Methods 0.000 abstract description 6
- 230000006872 improvement Effects 0.000 abstract description 3
- 231100000419 toxicity Toxicity 0.000 abstract description 3
- 230000001988 toxicity Effects 0.000 abstract description 3
- 239000007791 liquid phase Substances 0.000 abstract description 2
- 235000010755 mineral Nutrition 0.000 description 59
- 210000003491 skin Anatomy 0.000 description 51
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 26
- 239000000126 substance Substances 0.000 description 14
- 238000012360 testing method Methods 0.000 description 14
- 230000009286 beneficial effect Effects 0.000 description 10
- 230000006870 function Effects 0.000 description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 8
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 8
- 241000736199 Paeonia Species 0.000 description 8
- 230000032683 aging Effects 0.000 description 8
- 239000003513 alkali Substances 0.000 description 8
- 239000003814 drug Substances 0.000 description 8
- 239000000463 material Substances 0.000 description 8
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 8
- 230000009471 action Effects 0.000 description 7
- 230000003110 anti-inflammatory effect Effects 0.000 description 7
- 239000006071 cream Substances 0.000 description 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 7
- 239000002904 solvent Substances 0.000 description 7
- 239000003381 stabilizer Substances 0.000 description 7
- 230000001256 tonic effect Effects 0.000 description 7
- 208000002874 Acne Vulgaris Diseases 0.000 description 6
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 6
- 206010000496 acne Diseases 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 239000011734 sodium Substances 0.000 description 6
- 238000010171 animal model Methods 0.000 description 5
- 239000012153 distilled water Substances 0.000 description 5
- 230000004060 metabolic process Effects 0.000 description 5
- 239000008213 purified water Substances 0.000 description 5
- 229910052710 silicon Inorganic materials 0.000 description 5
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 4
- 206010014970 Ephelides Diseases 0.000 description 4
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 description 4
- 206010020772 Hypertension Diseases 0.000 description 4
- 208000003351 Melanosis Diseases 0.000 description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 239000011575 calcium Substances 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
- 235000011187 glycerol Nutrition 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 229930014626 natural product Natural products 0.000 description 4
- 239000011148 porous material Substances 0.000 description 4
- 229910000027 potassium carbonate Inorganic materials 0.000 description 4
- 239000002994 raw material Substances 0.000 description 4
- 241000208340 Araliaceae Species 0.000 description 3
- QPLDLSVMHZLSFG-UHFFFAOYSA-N Copper oxide Chemical compound [Cu]=O QPLDLSVMHZLSFG-UHFFFAOYSA-N 0.000 description 3
- 208000002193 Pain Diseases 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 206010040880 Skin irritation Diseases 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 230000003213 activating effect Effects 0.000 description 3
- 229910052783 alkali metal Inorganic materials 0.000 description 3
- 150000001340 alkali metals Chemical class 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 229910052791 calcium Inorganic materials 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 239000013078 crystal Substances 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 230000001882 diuretic effect Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 230000012010 growth Effects 0.000 description 3
- 229910052742 iron Inorganic materials 0.000 description 3
- 229910052749 magnesium Inorganic materials 0.000 description 3
- 239000011777 magnesium Substances 0.000 description 3
- 239000000395 magnesium oxide Substances 0.000 description 3
- CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 description 3
- AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 description 3
- 231100000252 nontoxic Toxicity 0.000 description 3
- 230000003000 nontoxic effect Effects 0.000 description 3
- NDLPOXTZKUMGOV-UHFFFAOYSA-N oxo(oxoferriooxy)iron hydrate Chemical compound O.O=[Fe]O[Fe]=O NDLPOXTZKUMGOV-UHFFFAOYSA-N 0.000 description 3
- 239000000049 pigment Substances 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 235000018102 proteins Nutrition 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 230000005855 radiation Effects 0.000 description 3
- 210000002374 sebum Anatomy 0.000 description 3
- 230000028327 secretion Effects 0.000 description 3
- 239000010703 silicon Substances 0.000 description 3
- 208000017520 skin disease Diseases 0.000 description 3
- 230000036556 skin irritation Effects 0.000 description 3
- 231100000475 skin irritation Toxicity 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 235000019640 taste Nutrition 0.000 description 3
- 235000013616 tea Nutrition 0.000 description 3
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 206010003645 Atopy Diseases 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 235000011201 Ginkgo Nutrition 0.000 description 2
- 240000004670 Glycyrrhiza echinata Species 0.000 description 2
- 229910021578 Iron(III) chloride Inorganic materials 0.000 description 2
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 2
- 239000004909 Moisturizer Substances 0.000 description 2
- 235000008708 Morus alba Nutrition 0.000 description 2
- 240000000249 Morus alba Species 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
- 201000004681 Psoriasis Diseases 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 244000269722 Thea sinensis Species 0.000 description 2
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 2
- 150000001342 alkaline earth metals Chemical class 0.000 description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 208000006673 asthma Diseases 0.000 description 2
- 238000011888 autopsy Methods 0.000 description 2
- QVQLCTNNEUAWMS-UHFFFAOYSA-N barium oxide Chemical compound [Ba]=O QVQLCTNNEUAWMS-UHFFFAOYSA-N 0.000 description 2
- 229940069765 bean extract Drugs 0.000 description 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 229910052796 boron Inorganic materials 0.000 description 2
- 150000001746 carotenes Chemical class 0.000 description 2
- 235000005473 carotenes Nutrition 0.000 description 2
- 230000020411 cell activation Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 244000013123 dwarf bean Species 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- YBMRDBCBODYGJE-UHFFFAOYSA-N germanium dioxide Chemical compound O=[Ge]=O YBMRDBCBODYGJE-UHFFFAOYSA-N 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 235000021331 green beans Nutrition 0.000 description 2
- 208000019622 heart disease Diseases 0.000 description 2
- 239000012676 herbal extract Substances 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 235000008216 herbs Nutrition 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 description 2
- VCJMYUPGQJHHFU-UHFFFAOYSA-N iron(3+);trinitrate Chemical compound [Fe+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O VCJMYUPGQJHHFU-UHFFFAOYSA-N 0.000 description 2
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 244000144972 livestock Species 0.000 description 2
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 description 2
- 239000000347 magnesium hydroxide Substances 0.000 description 2
- 229910001862 magnesium hydroxide Inorganic materials 0.000 description 2
- 239000011259 mixed solution Substances 0.000 description 2
- 230000001333 moisturizer Effects 0.000 description 2
- 239000005445 natural material Substances 0.000 description 2
- 208000004296 neuralgia Diseases 0.000 description 2
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 229960003975 potassium Drugs 0.000 description 2
- 229910052700 potassium Inorganic materials 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
- 235000007686 potassium Nutrition 0.000 description 2
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 2
- 239000013535 sea water Substances 0.000 description 2
- 239000000932 sedative agent Substances 0.000 description 2
- 230000001624 sedative effect Effects 0.000 description 2
- 238000000638 solvent extraction Methods 0.000 description 2
- 239000011550 stock solution Substances 0.000 description 2
- 235000000346 sugar Nutrition 0.000 description 2
- 239000011593 sulfur Substances 0.000 description 2
- 229910052717 sulfur Inorganic materials 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 239000001648 tannin Substances 0.000 description 2
- 235000018553 tannin Nutrition 0.000 description 2
- 229920001864 tannin Polymers 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 231100000820 toxicity test Toxicity 0.000 description 2
- 235000019155 vitamin A Nutrition 0.000 description 2
- 239000011719 vitamin A Substances 0.000 description 2
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 2
- 229940045997 vitamin a Drugs 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- YEFOAORQXAOVJQ-UHFFFAOYSA-N wuweizischun A Natural products C1C(C)C(C)(O)CC2=CC(OC)=C(OC)C(OC)=C2C2=C1C=C(OC)C(OC)=C2OC YEFOAORQXAOVJQ-UHFFFAOYSA-N 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- MJYQFWSXKFLTAY-OVEQLNGDSA-N (2r,3r)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]butane-1,4-diol;(2r,3r,4s,5s,6r)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O.C1=C(O)C(OC)=CC(C[C@@H](CO)[C@H](CO)CC=2C=C(OC)C(O)=CC=2)=C1 MJYQFWSXKFLTAY-OVEQLNGDSA-N 0.000 description 1
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- 229930024421 Adenine Natural products 0.000 description 1
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 description 1
- 229910018072 Al 2 O 3 Inorganic materials 0.000 description 1
- QQUHMASGPODSIW-UHFFFAOYSA-N Albiflorin Natural products C=1C=CC=CC=1C(=O)OCC12C(=O)OC3(C)CC(O)C1CC32OC1OC(CO)C(O)C(O)C1O QQUHMASGPODSIW-UHFFFAOYSA-N 0.000 description 1
- 229910000789 Aluminium-silicon alloy Inorganic materials 0.000 description 1
- 235000009292 Asparagus cochinchinensis Nutrition 0.000 description 1
- 244000248539 Asparagus cochinchinensis Species 0.000 description 1
- 239000005711 Benzoic acid Substances 0.000 description 1
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 description 1
- 229930192694 Caryophyllenol Natural products 0.000 description 1
- 241001070941 Castanea Species 0.000 description 1
- 235000014036 Castanea Nutrition 0.000 description 1
- 241000283026 Cervus elaphus Species 0.000 description 1
- 241000283007 Cervus nippon Species 0.000 description 1
- 206010008479 Chest Pain Diseases 0.000 description 1
- 239000005751 Copper oxide Substances 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 241000283074 Equus asinus Species 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 description 1
- PMVSDNDAUGGCCE-TYYBGVCCSA-L Ferrous fumarate Chemical compound [Fe+2].[O-]C(=O)\C=C\C([O-])=O PMVSDNDAUGGCCE-TYYBGVCCSA-L 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 208000013016 Hypoglycemia Diseases 0.000 description 1
- 208000001953 Hypotension Diseases 0.000 description 1
- 229910021575 Iron(II) bromide Inorganic materials 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 235000003228 Lactuca sativa Nutrition 0.000 description 1
- 240000008415 Lactuca sativa Species 0.000 description 1
- 241000134253 Lanka Species 0.000 description 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 1
- 241000234280 Liliaceae Species 0.000 description 1
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 1
- 241000218213 Morus <angiosperm> Species 0.000 description 1
- 229910002651 NO3 Inorganic materials 0.000 description 1
- 238000011887 Necropsy Methods 0.000 description 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 235000008598 Paeonia lactiflora Nutrition 0.000 description 1
- 244000236658 Paeonia lactiflora Species 0.000 description 1
- YKRGDOXKVOZESV-WRJNSLSBSA-N Paeoniflorin Chemical compound C([C@]12[C@H]3O[C@]4(O)C[C@](O3)([C@]1(C[C@@H]42)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C)OC(=O)C1=CC=CC=C1 YKRGDOXKVOZESV-WRJNSLSBSA-N 0.000 description 1
- 241001474977 Palla Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 208000012641 Pigmentation disease Diseases 0.000 description 1
- 241000037813 Polygonatum falcatum Species 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 235000014443 Pyrus communis Nutrition 0.000 description 1
- MUPFEKGTMRGPLJ-RMMQSMQOSA-N Raffinose Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O[C@@]2(CO)[C@H](O)[C@@H](O)[C@@H](CO)O2)O1)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 MUPFEKGTMRGPLJ-RMMQSMQOSA-N 0.000 description 1
- 241000218201 Ranunculaceae Species 0.000 description 1
- 241000405911 Rehmannia glutinosa Species 0.000 description 1
- 241000220222 Rosaceae Species 0.000 description 1
- 244000178231 Rosmarinus officinalis Species 0.000 description 1
- 206010039792 Seborrhoea Diseases 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 206010040914 Skin reaction Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- WGLPBDUCMAPZCE-UHFFFAOYSA-N Trioxochromium Chemical compound O=[Cr](=O)=O WGLPBDUCMAPZCE-UHFFFAOYSA-N 0.000 description 1
- MUPFEKGTMRGPLJ-UHFFFAOYSA-N UNPD196149 Natural products OC1C(O)C(CO)OC1(CO)OC1C(O)C(O)C(O)C(COC2C(C(O)C(O)C(CO)O2)O)O1 MUPFEKGTMRGPLJ-UHFFFAOYSA-N 0.000 description 1
- 208000006568 Urinary Bladder Calculi Diseases 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 229930003316 Vitamin D Natural products 0.000 description 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 1
- 238000011047 acute toxicity test Methods 0.000 description 1
- 229960000643 adenine Drugs 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- 238000003915 air pollution Methods 0.000 description 1
- QQUHMASGPODSIW-ICECTASOSA-N albiflorin Chemical compound O([C@@]12C[C@H]3[C@H](O)C[C@@]1(OC(=O)[C@]32COC(=O)C=1C=CC=CC=1)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O QQUHMASGPODSIW-ICECTASOSA-N 0.000 description 1
- 239000012670 alkaline solution Substances 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910001579 aluminosilicate mineral Inorganic materials 0.000 description 1
- ANBBXQWFNXMHLD-UHFFFAOYSA-N aluminum;sodium;oxygen(2-) Chemical compound [O-2].[O-2].[Na+].[Al+3] ANBBXQWFNXMHLD-UHFFFAOYSA-N 0.000 description 1
- 230000000954 anitussive effect Effects 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000001760 anti-analgesic effect Effects 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 230000002180 anti-stress Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 229940124584 antitussives Drugs 0.000 description 1
- 125000004429 atom Chemical group 0.000 description 1
- 210000000467 autonomic pathway Anatomy 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 235000010233 benzoic acid Nutrition 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 235000013734 beta-carotene Nutrition 0.000 description 1
- 239000011648 beta-carotene Substances 0.000 description 1
- 210000000941 bile Anatomy 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 229910052810 boron oxide Inorganic materials 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000004067 bulking agent Substances 0.000 description 1
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 description 1
- 239000000292 calcium oxide Substances 0.000 description 1
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 239000003575 carbonaceous material Substances 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 208000016252 change in skin color Diseases 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
- 229910000423 chromium oxide Inorganic materials 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 229910000428 cobalt oxide Inorganic materials 0.000 description 1
- IVMYJDGYRUAWML-UHFFFAOYSA-N cobalt(ii) oxide Chemical compound [Co]=O IVMYJDGYRUAWML-UHFFFAOYSA-N 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229910000431 copper oxide Inorganic materials 0.000 description 1
- 239000007799 cork Substances 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 239000008406 cosmetic ingredient Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 230000001877 deodorizing effect Effects 0.000 description 1
- 238000003795 desorption Methods 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- JKWMSGQKBLHBQQ-UHFFFAOYSA-N diboron trioxide Chemical compound O=BOB=O JKWMSGQKBLHBQQ-UHFFFAOYSA-N 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- PCHPORCSPXIHLZ-UHFFFAOYSA-N diphenhydramine hydrochloride Chemical compound [Cl-].C=1C=CC=CC=1C(OCC[NH+](C)C)C1=CC=CC=C1 PCHPORCSPXIHLZ-UHFFFAOYSA-N 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 235000018927 edible plant Nutrition 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000005868 electrolysis reaction Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 239000000686 essence Substances 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 229960004887 ferric hydroxide Drugs 0.000 description 1
- 229940046149 ferrous bromide Drugs 0.000 description 1
- 229960002089 ferrous chloride Drugs 0.000 description 1
- 239000011773 ferrous fumarate Substances 0.000 description 1
- 235000002332 ferrous fumarate Nutrition 0.000 description 1
- 229960000225 ferrous fumarate Drugs 0.000 description 1
- 229940076136 ferrous iodide Drugs 0.000 description 1
- 239000011790 ferrous sulphate Substances 0.000 description 1
- 235000003891 ferrous sulphate Nutrition 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000004426 flaxseed Nutrition 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 229960002737 fructose Drugs 0.000 description 1
- 150000008195 galaktosides Chemical class 0.000 description 1
- FOYKKGHVWRFIBD-UHFFFAOYSA-N gamma-tocopherol acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 FOYKKGHVWRFIBD-UHFFFAOYSA-N 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 229940119177 germanium dioxide Drugs 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 229940107131 ginseng root Drugs 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 230000036543 hypotension Effects 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 229910017053 inorganic salt Inorganic materials 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- NMCUIPGRVMDVDB-UHFFFAOYSA-L iron dichloride Chemical compound Cl[Fe]Cl NMCUIPGRVMDVDB-UHFFFAOYSA-L 0.000 description 1
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 1
- IEECXTSVVFWGSE-UHFFFAOYSA-M iron(3+);oxygen(2-);hydroxide Chemical compound [OH-].[O-2].[Fe+3] IEECXTSVVFWGSE-UHFFFAOYSA-M 0.000 description 1
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 1
- SZVJSHCCFOBDDC-UHFFFAOYSA-N iron(II,III) oxide Inorganic materials O=[Fe]O[Fe]O[Fe]=O SZVJSHCCFOBDDC-UHFFFAOYSA-N 0.000 description 1
- GYCHYNMREWYSKH-UHFFFAOYSA-L iron(ii) bromide Chemical compound [Fe+2].[Br-].[Br-] GYCHYNMREWYSKH-UHFFFAOYSA-L 0.000 description 1
- BQZGVMWPHXIKEQ-UHFFFAOYSA-L iron(ii) iodide Chemical compound [Fe+2].[I-].[I-] BQZGVMWPHXIKEQ-UHFFFAOYSA-L 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 239000004922 lacquer Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 229960004194 lidocaine Drugs 0.000 description 1
- ZOLPMMWNCLHKPX-UHFFFAOYSA-N ligustrin Natural products CC1=CCC2C1C3OC(=C)C(=O)C3C(O)CC2=C ZOLPMMWNCLHKPX-UHFFFAOYSA-N 0.000 description 1
- 229940057995 liquid paraffin Drugs 0.000 description 1
- FUJCRWPEOMXPAD-UHFFFAOYSA-N lithium oxide Chemical compound [Li+].[Li+].[O-2] FUJCRWPEOMXPAD-UHFFFAOYSA-N 0.000 description 1
- 229910001947 lithium oxide Inorganic materials 0.000 description 1
- 239000010871 livestock manure Substances 0.000 description 1
- 239000003589 local anesthetic agent Substances 0.000 description 1
- 229960005015 local anesthetics Drugs 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 1
- 239000001095 magnesium carbonate Substances 0.000 description 1
- 229910000021 magnesium carbonate Inorganic materials 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 229910052748 manganese Inorganic materials 0.000 description 1
- 239000011572 manganese Substances 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000003990 molecular pathway Effects 0.000 description 1
- 229910000476 molybdenum oxide Inorganic materials 0.000 description 1
- 230000004899 motility Effects 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 201000009240 nasopharyngitis Diseases 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 238000011587 new zealand white rabbit Methods 0.000 description 1
- 229910000480 nickel oxide Inorganic materials 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000019645 odor Nutrition 0.000 description 1
- 239000003129 oil well Substances 0.000 description 1
- 230000037312 oily skin Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 229940124595 oriental medicine Drugs 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- PQQKPALAQIIWST-UHFFFAOYSA-N oxomolybdenum Chemical compound [Mo]=O PQQKPALAQIIWST-UHFFFAOYSA-N 0.000 description 1
- GNRSAWUEBMWBQH-UHFFFAOYSA-N oxonickel Chemical compound [Ni]=O GNRSAWUEBMWBQH-UHFFFAOYSA-N 0.000 description 1
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 description 1
- YKRGDOXKVOZESV-UHFFFAOYSA-N paeoniflorin Natural products O1C(C)(C2(CC34)OC5C(C(O)C(O)C(CO)O5)O)CC3(O)OC1C24COC(=O)C1=CC=CC=C1 YKRGDOXKVOZESV-UHFFFAOYSA-N 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 230000003836 peripheral circulation Effects 0.000 description 1
- JRKICGRDRMAZLK-UHFFFAOYSA-L peroxydisulfate Chemical compound [O-]S(=O)(=O)OOS([O-])(=O)=O JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 230000003863 physical function Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- CHWRSCGUEQEHOH-UHFFFAOYSA-N potassium oxide Chemical compound [O-2].[K+].[K+] CHWRSCGUEQEHOH-UHFFFAOYSA-N 0.000 description 1
- 229910001950 potassium oxide Inorganic materials 0.000 description 1
- 235000019353 potassium silicate Nutrition 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 210000001747 pupil Anatomy 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000000191 radiation effect Effects 0.000 description 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000004648 relaxation of smooth muscle Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 235000019643 salty taste Nutrition 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 230000037307 sensitive skin Effects 0.000 description 1
- 150000004760 silicates Chemical class 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 230000035483 skin reaction Effects 0.000 description 1
- 231100000430 skin reaction Toxicity 0.000 description 1
- 229910001388 sodium aluminate Inorganic materials 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- KKCBUQHMOMHUOY-UHFFFAOYSA-N sodium oxide Chemical compound [O-2].[Na+].[Na+] KKCBUQHMOMHUOY-UHFFFAOYSA-N 0.000 description 1
- 229910001948 sodium oxide Inorganic materials 0.000 description 1
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
- 229940001474 sodium thiosulfate Drugs 0.000 description 1
- 235000019345 sodium thiosulphate Nutrition 0.000 description 1
- 239000008234 soft water Substances 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 235000019654 spicy taste Nutrition 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 238000001256 steam distillation Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- QJVXKWHHAMZTBY-GCPOEHJPSA-N syringin Chemical compound COC1=CC(\C=C\CO)=CC(OC)=C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 QJVXKWHHAMZTBY-GCPOEHJPSA-N 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 238000007669 thermal treatment Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- 239000010930 yellow gold Substances 0.000 description 1
- 229910001097 yellow gold Inorganic materials 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
- 229960001296 zinc oxide Drugs 0.000 description 1
- 229910001928 zirconium oxide Inorganic materials 0.000 description 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/02—Algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/254—Acanthopanax or Eleutherococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/985—Skin or skin outgrowth, e.g. hair, nails
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Zoology (AREA)
- Cosmetics (AREA)
Abstract
본 발명은 무기 광물 용해액 및 천연물 식물 추출물을 주재로 한 한방 화장료 조성물 및 그의 제조 방법에 관한 것으로서, 더욱 구체적으로는 주성분으로서 액상에서 다량의 음이온 및 원적외선을 방사하는 광물질 용해액과 천연 식물 추출물을 포함하는 천연 화장료 조성물 및 그의 제조 방법에 관한 것이다. 본 발명의 한방 화장료 조성물은 천연 성분으로 이루어져 있으므로, 피부에 대한 자극성이나 독성이 없어서 안정성이 우수하고, 피부 미백 등에 탁월한 효과를 갖고 있을 뿐만 아니라 피부에 대한 보습 효과, 피부 촉감 개선 및 지방 성분 제거 등 여러 가지 유익한 기능을 제공한다. The present invention relates to a herbal cosmetic composition based on inorganic mineral solution and natural plant extracts, and to a method for producing the same. More specifically, the present invention relates to a mineral dissolution solution and a natural plant extract that radiate a large amount of anions and far infrared rays in the liquid phase as main components. It relates to a natural cosmetic composition comprising and a method for producing the same. Since the herbal cosmetic composition of the present invention is composed of natural ingredients, there is no irritation or toxicity to the skin, so it is excellent in stability and has excellent effects on skin whitening, etc., as well as moisturizing effect on skin, skin feel improvement, and removal of fat components. It offers several useful features.
식물 추출물, 무기 광물, 화장료 조성물Plant extracts, inorganic minerals, cosmetic compositions
Description
본 발명은 무기 광물 용해액 및 천연 식물 추출물을 주재로 한 한방 화장료 조성물 및 그의 제조 방법에 관한 것으로서, 더욱 구체적으로는 주성분으로서 액상에서 다량의 음이온 및 원적외선을 방사하는 천연 광물질 용해액과 천연 식물 추출물을 포함하는 천연 화장료 조성물 및 그의 제조 방법에 관한 것이다. The present invention relates to an herbal cosmetic composition mainly composed of an inorganic mineral solution and a natural plant extract, and more particularly, a natural mineral solution and a natural plant extract that radiates a large amount of anions and far infrared rays in the liquid phase as main components. It relates to a natural cosmetic composition and a method for producing the same.
피부는 외부 환경과 직접 접하면서 인체를 보호하며 생화학적, 물리적인 기능을 가지고 있는 아주 중요한 조직이다. 날로 심각해지는 공기오염 문제와 함께 오존층의 파괴로 인한 자외선의 노출 등으로 피부가 손상될 우려가 매우 높아서 화장품이나 또는 화장에 관련된 기능성 제품의 선택은 부작용에 대한 우려와 함께 깨끗하고 하얀 피부의 선호도의 관점에서 매우 중요한 문제로 대두되고 있다. 또한, 최근 오존층의 파괴로 인하여 자외선의 노출이 심화되고, 이에 따라 피부의 보호를 위한 많은 제품들이 개발되고 있다. 색소 관련 피부 질환, 예를 들면 기미, 주근깨, 검버섯 등은 멜라닌이 국소적으로 과도하게 합성되거나 또는 노화 등의 원인에 따라 생리기능이 떨어져서 멜라닌이 피부 표면에 침착되어 유발되는 것으로 알려져 있다. Skin is a very important tissue that protects the human body while having direct contact with the external environment and has biochemical and physical functions. As there is a high risk of damage to the skin due to exposure to ultraviolet rays due to the destruction of the ozone layer along with the serious air pollution problem, the selection of functional products related to cosmetics or cosmetics is concerned with the side effects of clean and white skin. It is a very important issue from the point of view. In addition, recently, due to the destruction of the ozone layer has been intensified exposure to ultraviolet rays, many products for the protection of the skin has been developed accordingly. Pigment-related skin diseases, for example, blemishes, freckles, blotch, etc. are known to be caused by melanin is locally synthesized excessively or physiological function is degraded due to aging and the melanin is deposited on the skin surface.
화장료는 메이크업 및 피부의 노폐물 또는 피지 등을 제거하여 피부를 청결하게 하기 위하여 사용된다. 화장료는 부작용이 없어야 하고, 인체 친화적이어야 하며, 특이 체질이나 아토피 피부 또는 민감성 피부에도 안심하고 사용할 수 있어야 한다. 식물성 천연물들은 안전성이 뛰어날 뿐만 아니라 인체에 유익한 여러 가지 성분들을 포함하고 있어서 미백, 보습 효과를 제공하는 성분으로서 선호되고 있다. 이에, 종래부터 피부 노화의 억제 기능을 가진 생약, 야채, 과일, 꽃 등으로부터 안전성이 뛰어나고 여러 가지 기능성을 제공하는 추출물을 찾고자 하는 노력이 있어 왔다.Cosmetics are used to clean the skin by removing makeup and sebum or sebum of the skin. Cosmetics should be free of side effects, human-friendly, and safe to use on specific constitutions, atopic or sensitive skin. Plant natural products are not only excellent in safety but also contain various ingredients beneficial to the human body, and thus are preferred as ingredients that provide whitening and moisturizing effects. Thus, there have been efforts to find an extract that is excellent in safety and provides various functionalities from herbals, vegetables, fruits, flowers and the like which have a function of suppressing skin aging.
최근 천연물을 이용하여 기미, 주근깨, 자외선 과다 노출로 인한 피부질환, 아토피성 피부질환 등을 개선하기 위한 제품의 개발이 활발하게 이루어지고 있으며, 그러한 예로는 아마씨를 함유한 마스크 팩(특허공개 제2003-0074510호, 2003.09.19), 녹두 껍질 추출물을 함유하는 미백화장료 조성물(특허공개 제 2003-0030237호, 2003.04.18), 녹두 추출물을 함유하는 미백화장료 조성물(특허공개 제2003-0038844호, 2000. 07.05) 등이 알려져 있다.Recently, the development of products to improve skin disease, atopic skin disease caused by overexposure, freckles, overexposure to ultraviolet rays, etc. using natural products, such as mask pack containing flaxseed (Patent Publication 2003) -0074510, 2003.09.19), whitening cosmetic composition containing mung bean peel extract (Patent Publication No. 2003-0030237, 2003.04.18), whitening cosmetic composition containing mung bean extract (Patent Publication No. 2003-0038844, 2000 07.05).
한편, 광물질이나 미네랄 성분들은 일반적으로 원적외선을 방사하는 것으로 알려져 있어서 이들도 역시 화장료 성분으로 이용하려는 몇몇 시도가 있다.On the other hand, minerals and minerals are generally known to emit far infrared rays, so there are also some attempts to use them as cosmetic ingredients.
원적외선은 전자파의 일종으로 적외선(0.76 ∼ 1000㎛) 중 파장이 긴 것을 지칭하며, 정확한 파장 영역의 경계는 명확하지는 않으나 보통 4 ∼ 20㎛ 범위의 것을 의미하며 가시광선보다 강한 열작용을 하며 방사에너지가 직접적이고 순간적인 열전달에 의해 빠르게 흑체를 가열하여, 에너지 절약효과가 커서 널리 이용되고 있는 유용한 마이크로파이다. 이 파장 영역은 생체 내로 잘 흡수되어 생체 내의 분자를 자극하여 활성화시키는 작용을 하게 된다. Far infrared ray is a kind of electromagnetic wave, which means long wavelength among infrared rays (0.76 ~ 1000㎛), and the boundary of the exact wavelength range is not clear but usually means 4 ~ 20㎛ range, and it has stronger heat action than visible light and direct radiation energy. It is a useful microwave that is widely used because it has a large energy saving effect by rapidly heating the black body by the instantaneous and instantaneous heat transfer. This wavelength region is well absorbed into the living body and acts to stimulate and activate molecules in the living body.
그러나, 지금까지 원적외선 방사 물질을 이용한 제품들은 원료인 원적외선 방사 광물이 고체 상태로 존재하기 때문에 원적외선의 방사가 불충분하고, 고온 예컨대, 200 ℃∼500℃의 열을 가하여야만 원적외선 방사효과가 있으므로 실온 또는 상온에서 우수한 효과를 기대하기 어려웠을 뿐만 아니라 재료의 처리 과정이 복잡하고 처리 과정에 있어서도 강산을 사용하는 등 환경에 악영향을 줄 우려가 있어서 목적하는 기능에 대하여 불충분한 경우가 대부분이었다. However, until now, products using far-infrared radiating materials have insufficient radiation of far-infrared due to the presence of raw far-infrared radiating minerals in a solid state, and have a far-infrared radiating effect only when heat is applied at a high temperature, for example, 200 ° C to 500 ° C. Not only was it difficult to expect an excellent effect at room temperature, but the processing of the material was complicated and there was a possibility of adversely affecting the environment such as the use of a strong acid in the processing, which was insufficient for the intended function.
더욱이, 유익한 원적외선을 방사하는 천연 광물질을 인체의 직접적인 건강 증진에 활용하려는 시도는 극소수에 불과하다.Moreover, very few attempts have been made to utilize the natural minerals that emit beneficial far-infrared rays in direct human health.
본 발명자는 인체에 유익한 기능성 물질을 천연 성분들로부터 탐색하고자 예의 연구하던 중, 여러 가지 광물을 후술하는 방법에 의해 처리하고 여기에 무기물 및(또는) 안정화제 등을 첨가하여 제조한 액상에서 원적외선을 방사하는 안정화된 광물 용해액과 여러 가지의 천연 식물 추출물을 배합하여 그의 기능성을 조사해 본 결과, 이것이 인체에 무해할 뿐만 아니라 피부의 신진 대사를 촉진하고, 피부 보습효과 및 미맥 기능을 제공하는 기능 외에도 다양한 유익한 기능을 제공함을 수 있음을 발견하고, 본 발명을 완성하기에 이르렀다. The present inventors have been intensively searching for functional substances beneficial to the human body from natural ingredients, and have processed far-infrared rays in a liquid prepared by treating various minerals by the method described below and adding inorganic and / or stabilizers thereto. Combining radiant stabilized mineral solution with various natural plant extracts to investigate its functionality, it is not only harmless to human body, but also promotes skin metabolism, provides skin moisturizing effect and microbe function. It has been discovered that various beneficial functions can be provided, and the present invention has been completed.
따라서, 본 발명의 목적은 생명체에 유해하지 않고, 환경친화적이며, 음이온 및 원적외선을 방출하는 광물질 용해액과 천연 식물 추출물, 구체적으로는 녹두, 오미자액, 오이, 천문동, 작약, 가시오가피, 숙지황, 녹용, 황정, 백봉령, 당귀, 율무, 감초, 상백피, 은행잎, 영지버섯 및 율피로 이루어진 군 중에서 선택된 하나 이상의 식물 추출물을 포함함으로써 피부에 유익한 다양한 기능성을 제공하는 천연물 유래의 화장료 조성물 및 그의 제조 방법을 제공하는데 있다.Therefore, the object of the present invention is not harmful to life, environmentally friendly, mineral dissolution and natural plant extracts that emit anions and far infrared rays, specifically mung bean, Schizandra chinensis, cucumber, Astronomical dong, Peony, Prickly pear, Sukjihwang, Deer Antler To provide a cosmetic composition and a method of producing a natural product that provides a variety of beneficial properties to the skin by including one or more plant extracts selected from the group consisting of Hwangjeong, Baekbongryeong, Angelica, Yulmu, Licorice, lettuce, Ginkgo biloba, Ganoderma lucidum and Yulpi It is.
본 발명은 더욱 추가의 일면에 있어서 상기 화장료 조성물을 포함함으로써 피부에 직접 접촉하여 피부 마사지와 보습 효과는 물론 피부 미백 효과도 함께 달성할 수 있고, 위생적으로 효율적으로 사용될 수 있는 일회용 제품, 예를 들면, 일회용 물티슈 제품, 마사지 팩, 일회용 물수건, 유아용 물티슈 등의 일회용 제품을 제공하는데 있다.In still another aspect, the present invention includes the cosmetic composition, which can be directly contacted with the skin to achieve a skin massage and moisturizing effect as well as a skin whitening effect, and can be used hygienically and efficiently, for example. To provide disposable products, such as disposable wipes products, massage packs, disposable towels, baby wipes.
본 발명은, 일면에 있어서, 음이온 및 원적외선을 방출하는 광물질 용해액과 녹두, 오미자액, 오이, 천문동, 작약, 가시오가피, 숙지황, 녹용, 황정, 백봉령, 당귀, 율무, 감초, 상백피, 은행잎, 영지버섯 및 율피로 이루어진 군 중에서 선택된 하나 이상의 천연 식물성 유래의 추출물을 포함함으로써 피부에 유익한 여러 가지의 기능성을 제공하는 천연물 유래의 화장료 조성물을 제공한다.The present invention, in one aspect, mineral dissolution and green beans, Schisandra chinensis, Cucumber, Cheonmundong, Peony, Prickly pear skin, Sukjihwang, Deer antler, Hwangjeong, Baekbongryeong, Donkey, Yulmu, Licorice, Sangbaekpi, Ginkgo leaf, Ganoderma lucidum The present invention provides a cosmetic composition derived from natural products that provides various functionalities beneficial to the skin by including extracts of at least one natural plant derived from the group consisting of mushrooms and yulpi.
상기 기능성 한방 화장료 조성물은The functional herbal cosmetic composition is
a) 광물질을 물 또는 알칼리수로 처리한 다음, 여기에 활성화 촉매로서 2가 철염 및 3가 철염, 규산소다 용액, 붕사 및 구연산칼륨을 첨가한 후 물, 과황산칼 륨 및 차아염소산나트륨과 함께 교반시키는 단계a) The minerals are treated with water or alkaline water, and then added thereto as an activation catalyst, divalent iron salts and trivalent iron salts, sodium silicate solution, borax and potassium citrate, followed by stirring with water, calcium persulfate and sodium hypochlorite Letting step
b) 녹두, 오미자, 천문동, 가시오가피, 녹용, 황정, 율피 단독 또는 하나 이상의 혼합물을 각각 세절하고 분말화하여 3~10 배수량의 탄소수 1-4개의 함수 또는 무수 저급알코올, 메탄올, 에탄올, 및 부탄올로 이루어진 군으로부터 선택된 유기 용매를 이용하여 30~100 ℃에서 1 시간 내지 1주일 동안 추출하는 단계,b) Shred and powder mung bean, Schisandra chinensis, Astronomical dong, Siberian ginseng, Deer antler, Yellowfin, Yulpi alone or one or more mixtures, respectively, with 3 ~ 10 multiples of 1-4 carbon atoms or anhydrous lower alcohol, methanol, ethanol, and butanol Extraction for 1 hour to 1 week at 30 ~ 100 ℃ using an organic solvent selected from the group consisting of,
c) 작약, 숙지황, 백봉령, 영지버섯, 감초, 은행잎, 당귀, 율무, 상백피 단독 또는 하나 이상의 혼합물을 세절하고 분말화하여 3~10 배수량의 물을 첨가하여 30~100 ℃에서 1 시간 내지 1주일 동안 추출하는 단계,c) Peony, Sukjihwang, Baekbongryeong, Ganoderma lucidum, Licorice, Ginkgo biloba, Angelica, Yulmu, Sangbaekpi alone or one or more mixtures are shredded and powdered, and 3 ~ 10 drainage of water is added for 1 hour to 1 week at 30-100 ℃. During the extraction step,
d) 오이를 착즙하여 즙을 내는 단계,d) juice the cucumbers to juice,
e) 상기 b) 및 c) 단계의 추출 후 남은 추출박에 3~10 배수량의 20~70% 농도의 상기 유기 용매로 30~100 ℃에서 1 시간 내지 1 주일 동안 재차 추출하여 유기 용매와 물에 용해되는 잔류 유효 성분을 추출하는 단계,e) extracted again with the organic solvent having a concentration of 20 to 70% of 3 to 10 times the remaining amount after the extraction of steps b) and c) again at 30 to 100 ℃ for 1 hour to 1 week to the organic solvent and water Extracting the remaining active ingredient to be dissolved,
f) 상기 e)단계의 추출 후 잔류 추출박을 3~10 배수량의 물로만 30~100 ℃에서 1 시간 내지 1주일 동안 추출하여 물에만 용해되는 성분을 추출하는 단계, 및f) extracting the components that are dissolved only in water by extracting the residual extraction foil after the extraction of step e) at 30-100 ° C. for 1 hour to 1 week only with 3 ~ 10 drainage water, and
g) 상기 a) 단계에서 얻은 광물질 용해 혼합물과 상기 b) 내지 f)단계에서 얻은 하나 이상의 천연 식물의 추출물을 중량을 기준으로 0.1~99.9:99.9~0.1로 혼합한 후, 이를 여과시킨 다음 감압 증류하여 혼합 추출물을 얻는 단계를 포함하는 것을 특징으로 한다.g) mixing the mineral dissolution mixture obtained in step a) and the extract of one or more natural plants obtained in steps b) to f) by 0.1 to 99.9: 99.9 to 0.1 based on weight, and then filtering and distilling under reduced pressure It characterized by comprising the step of obtaining a mixed extract.
본 발명에 따른 화장료 조성물은 피부 사용감이 우수하고 피부 자극성이 적을 뿐만 아니라 피부 상태를 활성화시키는 등 인체에 유익한 여러 가지 기능성을 나타낸다.The cosmetic composition according to the present invention exhibits various functionalities that are beneficial to the human body, such as excellent skin feel and less skin irritation, as well as activating skin conditions.
이하, 본 발명의 기능성 화장료 조성물 및 그의 제조 방법에 관하여 더욱 상세히 설명한다.Hereinafter, the functional cosmetic composition of the present invention and a manufacturing method thereof will be described in more detail.
본 발명에 따른 천연 화장료 조성물의 일 구성 성분인 상기 광물질 용해액은 하나 이상의 천연 광물질을 물 또는 알칼리수로 처리하여 용해시키고 상기 용해액에 무기염, 금속이온 등의 안정화제 등을 첨가하여 제조할 수 있고, 이는 무독성의 알칼리성 용해액의 상태로서 상온에서 다량이 음이온 및 원적외선을 방사하므로 최소한의 활성화 에너지에 의해 피부에 유익한 여러 가지의 기능성을 제공한다.The mineral solution, which is one component of the natural cosmetic composition according to the present invention, may be prepared by treating one or more natural minerals with water or alkaline water to dissolve and adding a stabilizer such as an inorganic salt or a metal ion to the solution. It is a state of non-toxic alkaline dissolving liquid, which emits large amounts of anions and far infrared rays at room temperature, thus providing various functionalities beneficial to the skin with minimal activation energy.
본 발명에 의해 천연 광물질을 액상화함으로써 실온 및 상온(20∼30℃)에서도 음이온 및 원적외선을 방사 효과를 나타내는 성분이 제공되며, 또한 원적외선 방사체를 액상화함으로써 물과 혼합이 용이하고 물분자를 활성화시킴으로써 물의 부패방지 등 보존안정성도 아울러 고려하였다.According to the present invention, by liquefying natural minerals, an ingredient which exhibits anion and far-infrared radiation effects even at room temperature and room temperature (20 to 30 ° C) is provided. Also, by liquefying the far-infrared radiator, it is easy to mix with water and activates water molecules. Preservation stability such as anti-corruption was also considered.
상기 광물 용해액은 인체에 무해하고 원적외선을 방사하는 천연 광물질 중에서 선택된다.The mineral solution is selected from natural minerals that are harmless to the human body and emit far infrared rays.
이러한 원적외선 방사 물질로는 규산나트륨, 알루미늄산나트륨, 티오황산나트륨, 이산화게르마늄, 산화아연, 산화칼륨, 산화붕소, 산화마그네슘, 산화알루미늄(Al2O3), 실리카(SiO2), 산화나트륨, 산화망간(MnO2), 산화구리CuO), 산화철, 산화지르코늄(ZrO2), 산화코발트, 산화니켈, 산화크롬, 산화티탄(TiO2), 산화몰리브덴, 탄소계 물질, 산화바륨, 산화리튬, 산화제2철(Fe2O3), 점토, 활석, 황토 등이 알려 져 있으며, 이러한 성분들은 여러 가지 점토나 광물 등에서 흔히 발견된다.Such far infrared emitting materials include sodium silicate, sodium aluminate, sodium thiosulfate, germanium dioxide, zinc oxide, potassium oxide, boron oxide, magnesium oxide, aluminum oxide (Al 2 O 3 ), silica (SiO 2 ), sodium oxide, and oxidation Manganese (MnO 2 ), copper oxide CuO, iron oxide, zirconium oxide (ZrO 2 ), cobalt oxide, nickel oxide, chromium oxide, titanium oxide (TiO 2 ), molybdenum oxide, carbonaceous material, barium oxide, lithium oxide, oxidizing agent Ferric iron (Fe 2 O 3 ), clay, talc, loess and the like are known, these components are commonly found in various clays and minerals.
이와 같은 광물들은 본 발명에서 제한 없이 사용할 수 있으나, 예를 들면 이들에 한정하지 않고, 토르말린, 제올라이트, 맥반석, 점토, 사문암, 각섬석, 벤토나이트 및 규조토 등을 들 수 있다.Such minerals can be used without limitation in the present invention, for example, but not limited to, tourmaline, zeolite, ganban stone, clay, serpentine, hornblende, bentonite and diatomaceous earth and the like.
본 발명에 따른 광물 용해액은 더욱 바람직하게는The mineral solution according to the present invention is more preferably
(a) 토르말린 분말을 물 또는 알칼리 수용액에 용해시켜 교반 하에 가열시켜 토르말린 용해액을 제조하는 단계,(a) dissolving the tourmaline powder in water or an aqueous alkali solution to heat it under stirring to prepare a tourmaline solution,
(b) 제올라이트를 알칼리 수용액에 용해시켜 제올라이트 용해액을 제조하는 단계, (b) dissolving the zeolite in an aqueous alkali solution to prepare a zeolite solution;
(c) 맥반석, 점토, 사문암, 각섬석, 벤토나이트, 규조토로 이루어진 군 중에서 선택된 하나 이상의 광물을 용해시켜 광물 용해액을 제조하는 단계,(c) dissolving at least one mineral selected from the group consisting of elvan, clay, serpentine, hornblende, bentonite, and diatomaceous earth to prepare a mineral solution,
(d) 상기 용해액들, 2가철염 및(또는) 3가철염, 규산소다 용액, 분사 및 구연산칼륨을 혼합하여 가열 및 교반 하에 숙성시킴으로써 혼합물의 형태로 얻는 것이 좋다.(d) It is preferable to obtain the above dissolved solution, ferric salt and / or trivalent salt, sodium silicate solution, spraying and potassium citrate by mixing and aging under heating and stirring to obtain a mixture.
본 발명의 명세서 및 특허청구범위의 기재에 있어서 원료 등을 혼합하는 여러 가지 비율은 편의상 액체일 경우에는 ml를 나타내고, 고체일 경우에는 g을 기준으로 한 값으로 정의한다. 또한, 각 성분의 혼합비에 관련하여 달리 기재하지 않는 한 구성비는 중량%로 정의한다.In the specification and claims of the present invention, various ratios of mixing the raw materials and the like are defined as ml for liquids and g-based for solids for convenience. In addition, the composition ratio is defined in weight percent unless otherwise stated in relation to the mixing ratio of each component.
본 발명의 기능성 화장료 조성물은 양이온 및 음이온의 밸런스를 충분히 유지할 수 있고, 체액을 약알칼리의 상태로 활성화시킬 수 있는 미네랄 및 상기한 바 의 성분들을 풍부하게 함유하는 여러 가지의 광물, 예를 들면 토르말린, 제올라이트, 점토 등의 규산염을 풍부하게 함유하는 광물을 물 또는 알칼리 수용액을 포함한 용매로 필요시 가열하에 용해시킨 다음 이를 물리적으로 처리하여 안정화시킨 다음, 이를 별도로 추출한 식물 성분과 혼합하여 제조할 수 있다.The functional cosmetic composition of the present invention is capable of sufficiently maintaining a balance of cations and anions, and various minerals, for example, tourmaline, which are rich in minerals capable of activating body fluids in the state of weak alkali and the above components. Minerals rich in silicates, such as zeolites and clays, may be prepared by dissolving them in a solvent containing water or an aqueous alkali solution, if necessary, under heating, then physically treating them to stabilize them, and then mixing them with separately extracted plant components. .
상기 광물 중에서, 토르말린(tourmaline)은 6각 주상형의 결정을 갖는 붕규산염으로 육방정계에 속하는 광물로서, 토르말린 결정 자체가 전기를 발생하는 특성을 지녀 전기석이라고도 한다. 토르말린은 그 결정구조에 따라 다양한 종류가 있으며, 주요 구성 성분으로는 종류에 따라 차이가 있으나 주로 Mg, Fe, B, Si, Ca 및 기타 알칼리 금속이 포함되어 있다. 토르말린은 원적외선을 방사하는 것으로 알려져 있고, 이전부터 화장품의 성분으로 사용되거나 섬유 등 생활 용품이나 건축물의 내장재 등으로 이용되고 있다. 토르말린에는 세포의 활성화와 심장 강화에 좋은 마그네슘, 피부의 점막 관계 및 성장 촉진을 돕는 붕소, 미용에 좋은 규소, 혈액 관계 및 심장 강화 등의 효과가 있는 철 및 신경 안정 효과가 있는 칼슘 등 인체에 좋은 영향을 주는 원소와 미네랄이 다량 함유되어 있다. 구체적으로, 토르말린의 전기적 특성으로 인하여 꾸준히 발생되는 미약한 전류가 인체의 경혈을 자극하여 말초 순환계를 개선하고 혈류를 촉진시켜 고혈압과 소추 질병에 효과가 있으며, 다량의 원적외선 방출로 인한 세포 활성화 작용으로 체질개선, 혈액 정화 작용 등의 전위 치료 효과가 있고, 혈행과 신진대사를 촉진하여 피로 회복, 위장 활성화, 통증과 숙면 및 냉증의 완화 등의 효과가 있다. 또한, 토르말린은 수분의 접촉을 통한 전기분해에 의해 다량의 음이온이 발생되므로 항균, 탈취 및 세정 효과가 있으 며, 산성화된 체액을 약알카리성 체질로 개선시켜 인체에 안정감을 주는 효능이 있다. 토르말린은 다이아몬드와 같이 투명한 것에서부터 핑크, 담녹색, 청색, 적색, 자색 등의 색채가 풍부하며, 브라질, 몽고, 캘리포니아, 스리랑카, 중국 등이 주산지이며 이들은 특별히 제한없이 사용할 수 있다.Among the minerals, tourmaline is a borosilicate having hexagonal columnar crystals and is a mineral belonging to a hexagonal system. Tourmaline is also called tourmaline because the tourmaline crystal itself generates electricity. There are various types of tourmaline according to its crystal structure, and main components include Mg, Fe, B, Si, Ca, and other alkali metals. Tourmaline is known to radiate far-infrared rays, and has been used as a component of cosmetics or as a living material such as textiles or interior materials of buildings. Tourmaline is good for the human body, such as magnesium, which is good for cell activation and heart strengthening, boron, which helps to promote the mucous membrane relationship and growth of the skin, and silicon, which is good for beauty, silicon, blood relationship, and calcium, which stabilizes the heart. It is rich in elements and minerals that affect it. Specifically, the weak current generated by the electrical properties of tourmaline stimulates the menstrual blood of the human body to improve peripheral circulation and promote blood flow, which is effective for hypertension and profound disease, and cell activation due to the release of large amounts of far infrared rays. It has the effect of dislocation treatment such as constitution improvement and blood purification, and it promotes blood circulation and metabolism, and it is effective in recovering fatigue, activating gastrointestinal tract, relieving pain and sleep and cold symptoms. In addition, tourmaline has a large amount of negative ions generated by electrolysis through contact with water, which has antibacterial, deodorizing, and cleaning effects, and improves acidified body fluids with weakly alkaline constitutions, thereby providing stability to the human body. Tourmaline is rich in colors such as diamond, transparent, pink, light green, blue, red, and purple. Brazil, Mongolia, California, Sri Lanka, China, etc. are mainly produced, and they can be used without particular limitation.
본 발명에 있어서, 토르말린은 피부를 활성화하고, 피부에 보습 효과를 나타내고, 화장료 추가 성분과 배합시 상승 작용을 발휘하는 성분으로서 채택되었다.In the present invention, tourmaline has been adopted as a component that activates the skin, exerts a moisturizing effect on the skin, and exerts a synergistic effect when combined with a cosmetic additional component.
토르말린 용해액을 제조하기 위해서는 우선 입수한 토르말린을 자동세척기로 깨끗하게 수세하여 이물질을 제거한 후 건조시키고, 이어서 분쇄기에서 분쇄하여 광물 용해액의 원료로 사용한다. 이 분말처리된 토르말린을 일정 온도, 예컨대 100∼150 ℃, 바람직하게는 약 100 ℃ 이상의 온도에서 용해 용매로서 물 또는 알칼리 수용액으로 처리하여 적절한 기간, 예컨대 1 시간 내지 24시간, 보다 바람직하게는 1 내지 7 시간 동안, 가장 바람직하게는 3시간 정도 교반하에 숙성시킴으로써 토르말린 용해액을 얻는다. 이때, 알칼리 용액을 사용하는 경우에는 pH 농도가 높은 강알칼리 수용액이 특히 바람직하게 사용될 수 있으며, 그 예로서는 수산화나트륨, 수산화칼륨, 탄산나트륨, 탄산칼륨 또는 이들의 혼합 용액을 들 수 있다. 특히, 탄산칼륨 수용액과 수산화칼륨 수용액의 혼합 용액을 사용하는 것이 바람직하다. To prepare the tourmaline solution, firstly, the obtained tourmaline is washed with an automatic washing machine to remove foreign substances, and then dried, and then pulverized in a grinder to be used as a raw material of the mineral solution. This powdered tourmaline is treated with water or an aqueous alkali solution as a dissolving solvent at a constant temperature, such as 100 to 150 ° C., preferably about 100 ° C. or higher, for a suitable period of time, such as 1 to 24 hours, more preferably 1 to 1 hour. A tourmaline solution is obtained by aging for 7 hours, most preferably with stirring for about 3 hours. At this time, in the case of using an alkaline solution, a strong alkaline aqueous solution having a high pH concentration may be particularly preferably used, and examples thereof include sodium hydroxide, potassium hydroxide, sodium carbonate, potassium carbonate or a mixed solution thereof. In particular, it is preferable to use a mixed solution of an aqueous potassium carbonate solution and an aqueous potassium hydroxide solution.
본 발명에서 광물 용해액으로 사용되는 알칼리 수용액은 예를 들면 증류수를 사용하거나 또는 증류수와 수산화칼륨을 약 1:0.5의 부피비로 혼합한 것 또는 증류수와 탄산칼륨을 약 1:0.5의 부피비로 혼합한 것을 단독으로 또는 혼합하여 사용하며, 토르말린 용해액의 제조시에는 상기 각각의 알칼리 수용액을 2:1의 비율로 사 용하는 것이 바람직할 수 있다. The alkaline aqueous solution used as the mineral solution in the present invention is, for example, using distilled water or a mixture of distilled water and potassium hydroxide in a volume ratio of about 1: 0.5 or a distilled water and potassium carbonate in a volume ratio of about 1: 0.5 It may be preferable to use them alone or in combination, and to use the respective aqueous alkali solution in a ratio of 2: 1 when preparing tourmaline solution.
토르말린 용해액의 제조시 KOH 용액:K2CO3 용액:토르말린 분말의 혼합비는 부피 및 중량을 기준으로 대략 3∼20:2∼10:1∼5:의 비율이 적당하다. 제조된 토르말린 용해은 48 시간 정도 정치한 다음 4 ℃에 보관한다.The ratio of KOH solution: K 2 CO 3 solution: tourmaline powder in the preparation of tourmaline solution is approximately 3-20: 2-10: 1-5: 5 based on volume and weight. The prepared tourmaline dissolution is allowed to stand for 48 hours and then stored at 4 ° C.
본 발명의 광물 용해액의 추가 성분으로서 제올라이트나 점토 등의 광물을 상기한 바와 유사한 방식으로 처리함으로써 광물 용해액을 제조할 수 있다. As an additional component of the mineral solution of the present invention, mineral solution can be prepared by treating minerals such as zeolite and clay in a similar manner as described above.
제올라이트(불석)는 다공성 물질로 화학실험 및 화학공업 분야에서 흡착제로 사용하거나, 경수를 연화시킬때 이온교환 등에 의한 경수연화제로 사용하여 왔고, 분뇨나 기타 쓰레기의 악취 제거에서 미생물과 함께 사용되기도 한다. 제올라이트는 알루미노실리케이트 광물의 일종으로 사면체인 TO4(T는 tetrahedral atom으로 Si 혹은 Al)로 이루어진 분자차원의 동공(cavity)들로 3차원으로 연결되어 분자차원의 통로를 구성하고 있다. 동공 내에서 일어나는 물분자의 가역적인 흡·탈착 현상을 일으키며 천연 제올라이트는 약 40 여종, 합성 제올라이트는 약 130 여종이 존재한다. 본 발명에 사용되는 제올라이트에는 특별한 제한은 없으며, 공지의 것을 사용할 수 있다.Zeolite is a porous material that has been used as an adsorbent in chemical experiments and the chemical industry, or as a water softener by ion exchange when softening soft water. It is also used with microorganisms to remove odors of manure and other wastes. . Zeolite is a kind of aluminosilicate mineral which is connected in three dimensions by molecular cavity consisting of tetrahedron TO 4 (T is tetrahedral atom, Si or Al) and constitutes molecular pathway. It causes reversible adsorption and desorption of water molecules in the pupil. There are about 40 kinds of natural zeolites and about 130 kinds of synthetic zeolites. The zeolite used in the present invention is not particularly limited, and known ones can be used.
본 발명에 따른 제올라이트 용해액을 얻고자 할 때는 제올라이트를 상기 수산화칼륨 원액에 첨가함으로서 특별한 조건을 부가하지 않고 일정 시간 동안, 예컨대 3 시간 정도 용해시킴으로써 제조한다. 특히 이때 열을 가하게 되면 제올라이트의 슬러리화가 일어나게 될 우려가 있으므로 제올라이트 용해액의 제조시에는 비열 처리가 바람직하다. 제올라이트 용해액은 상기 수산화칼륨 원액:제올라이트의 비율을 바람직하게는 대략 2.5∼10:0.5∼2의 비율로 하여 혼합하는 것이 좋다. 그러나, 상기 설정한 범위는 본 발명을 더욱 이해하기 용이하게 제시한 범위이지 본 발명은 이러한 범위에만 한정되는 것은 아니다. In order to obtain the zeolite solution according to the present invention, it is prepared by adding zeolite to the potassium hydroxide stock solution by dissolving for a predetermined time, for example, about 3 hours without adding special conditions. Particularly, when heat is applied, there is a risk that the zeolite may be slurried, and thus, non-thermal treatment is preferable at the time of preparing the zeolite solution. The zeolite dissolving solution is preferably mixed at a ratio of the potassium hydroxide solution: zeolite in a ratio of approximately 2.5 to 10: 0.5 to 2. However, the above-mentioned range is a range presented to make the present invention easier to understand, but the present invention is not limited to this range.
맥반석은 다공질 구조로, 색은 황백색의 광물로서 그 주성분이 실리카, 산화알루미늄, 산화철, 산화마그네슘, 산화칼슘을 포함하므로 원적외선 방사체의 재료로 사용하기에 적합하다.Elvan has a porous structure and is a yellowish-white mineral whose main components include silica, aluminum oxide, iron oxide, magnesium oxide, and calcium oxide, making it suitable for use as a material for far-infrared radiators.
맥반석 용해액을 얻고자 할 때는 맥반석을 상기 수산화칼륨 원액에 첨가한후, 상기 토르말린 용해액의 제조 조건과 유사하게 처리함으로써 얻을 수 있다. 즉, 맥반석 함유 알칼리 수용액을 일정 온도, 예컨대 100∼150 ℃, 바람직하게는 약 100 ℃ 이하, 가장 바람직하게는 75∼85 ℃의 온도에서 용매로서 알칼리 수용액을 사용하여 적절한 기간, 예컨대 1 시간 내지 24시간, 보다 바람직하게는 1 내지 7시간 동안, 가장 바람직하게는 3시간 정도 교반 하에 숙성시킴으로써 맥반석 용해액을 얻는다. When the elvan solution is to be obtained, it can be obtained by adding elvan to the potassium hydroxide stock solution and treating the tourmaline dissolution solution in a similar manner. In other words, the aqueous solution of alkaline water containing elvan is used at an appropriate temperature, such as 100 to 150 ° C., preferably about 100 ° C. or lower, and most preferably 75 to 85 ° C., using an aqueous alkali solution as a solvent for a suitable period of time, such as 1 hour to 24 hours. Elvan rock solution is obtained by aging under stirring for an hour, more preferably 1 to 7 hours, most preferably about 3 hours.
맥반석 용해액은 상기 수산화칼륨 용액:맥반석을 중량을 기준으로 대략 2.5∼10:0.5∼2의 비율로 하여 혼합하는 것이 좋다.The elvan solution is preferably mixed with the potassium hydroxide solution: elvan in a ratio of approximately 2.5 to 10: 0.5 to 2 based on weight.
상기 성분 이외에도, 점토에는 규소, 알루미늄, 철, 마그네슘, 알칼리금속, 알칼리토금속 등을 함유하고 있으므로 이들을 광물 용해액도 사용 가능하며, 이외에도, 맥섬석, 사문암, 각섬석, 벤토나이트, 규조토 등을 본 발명의 알칼리수로 처리하여 광물 용해액으로 사용하여 여러 가지 알칼리 용해액을 제조하는 것이 가능 하다.In addition to the above components, the clay contains silicon, aluminum, iron, magnesium, alkali metals, alkaline earth metals, and the like, and mineral dissolving liquids can also be used. In addition, macsumite, serpentine, hornblende, bentonite, diatomaceous earth, and the like can be used in the alkaline water of the present invention. It is possible to prepare various alkali solutions by treating with a mineral solution.
이와 같이 개별적으로 제조된 상기 광물 용해액들은 각각 원적외선을 방사하는 등의 그 자체로도 기능성이 있어서 단독으로 사용할 수도 있으나, 이를 일정 비율로 혼합하여 다양한 생화학적 기능을 갖는 광물 용해액 혼합물을 제조하는 것이 더욱 바람직하다.The separately prepared mineral dissolving liquids can be used alone because they are functional in themselves, such as emitting far infrared rays, respectively, but they are mixed at a predetermined ratio to prepare a mineral dissolving liquid mixture having various biochemical functions. More preferred.
이와 같이 개별적으로 제조된 광물 용해액에 안정화제로서 철염, 특히 2가철염 및(또는) 3가철염을 소량 첨가하는 것이 좋으며, 본 발명에 사용가능한 2가철염은 예를 들면 산화제1철, 황산제1철, 염화제1철, 질산제1철, 브롬화제1철, 요오도화제1철 등의 무기철염이나 몰식자산제1철, 사과산제1철, 푸마르산제1철 등의 유기철염을 사용할 수 있으며, 3가 철염으로는 산화제2철, 염화제2철, 수산화제2철, 질산제2철 등을 사용할 수 있다. 마찬가지로 사용가능한 추가의 안정화제로서는 주기율표 I족의 알칼리금속 및 II족의 알칼리토금속의 무기염을 예로들 수 있으며, 그 예로는 탄산마그네슘, 수산화마그네슘, 수산화탄산마그네슘, 산화마그네슘 등을 적절하게 사용해도 좋다. 상기 안정화제는 광물 용해액 조성물의 전체 중량을 기준으로 5중량%이하로 사용하는 것이 좋다.It is advisable to add a small amount of iron salts, in particular ferric salts and / or trivalent iron salts, as stabilizers to the separately prepared mineral solutions, and the ferric salts usable in the present invention are, for example, ferrous oxide and sulfuric acid. Inorganic iron salts such as ferrous iron, ferrous chloride, ferrous nitrate, ferrous bromide, ferrous iodide, and organic iron salts such as ferrous molten iron, ferrous malic acid, and ferrous fumarate can be used. Examples of the trivalent iron salt include ferric oxide, ferric chloride, ferric hydroxide, and ferric nitrate. Likewise additional stabilizers that can be used include inorganic salts of the alkali metals of the Group I and alkaline earth metals of the Periodic Table, examples of which include magnesium carbonate, magnesium hydroxide, magnesium hydroxide, magnesium oxide, and the like. good. The stabilizer is preferably used in less than 5% by weight based on the total weight of the mineral solution liquid composition.
본 발명의 광물 용해액의 혼합물은 상기 토르말린 용해액, 제올라이트 용해액, 규산소다 용액(Na2O·nSiO2-xH2O, 물유리), 붕사(Na2B 4O7), 철염 및 구연산칼륨(K2C6H5O7)을 적정한 비율로 혼합시킨 다음, 실온에서 내지 100 ℃ 이하의 온도, 바람직하게는 80 ℃ 이하의 온도에서 적당한 기간, 예컨대 10분 내지 5시간, 보다 바 람직하게는 10분 내지 3 시간 동안, 가장 바람직하게는 1시간 정도 교반 하에 숙성시킴으로써 안정화시킨 혼합 용해액의 형태로 사용된다.The mixture of the mineral solution of the present invention is the tourmaline solution, zeolite solution, sodium silicate solution (Na 2 O · nSiO 2 -xH 2 O, water glass), borax (Na 2 B 4 O 7 ), iron salt and potassium citrate (K 2 C 6 H 5 O 7 ) is mixed at an appropriate ratio, and then at a suitable temperature at room temperature up to 100 ° C., preferably up to 80 ° C., for a suitable period of time, such as 10 minutes to 5 hours, more preferably. Is used in the form of a mixed dissolution stabilized by aging for 10 minutes to 3 hours, most preferably about 1 hour with stirring.
상기 광물 용해액들은 기능성 물질로서 작용하며, 철염, 규산소다용액, 붕사, 구연산칼륨 등은 보조 기능성 물질 또는 안정화제로서 작용한다.The mineral solutions serve as functional substances, and iron salts, sodium silicate solutions, borax, potassium citrate, and the like act as auxiliary functional substances or stabilizers.
상기 광물 용해액에 추가의 기능성 향상을 위한 미량 성분으로서 유기 게르마늄 및 셀레늄, 은 수용액 등을 첨가하여 사용해도 좋다.You may use organic germanium, selenium, silver aqueous solution, etc. as a trace component for further improving a function to the said mineral solution.
상기 안정화된 광물 용해액의 제조시, 광물 용해액:규산소다 용해액:붕사:구연산칼륨:철염의 혼합비는 부피 및 중량을 기준으로 대략 80∼99.6:0.1∼5:0.1∼5:0.1∼5:0.1∼5의 비율, 더욱 바람직하게는 91∼99.2:0.2∼2:0.2∼2:0.2∼2:0.2∼3의 비율, 가장 바람직하게는 99:0.2:0.2:0.2:0.4의 비율로 혼합한다. 물론 상기 조성이 이러한 범위를 벗어나더라도 기능성이 다소 낮아지는 것 외에는 본질적인 기능성의 문제는 없으므로 본 발명의 광물 용해액의 조성은 상기한 범위에만 한정되는 것이 아니며 상기 조성비의 범위에서 다소 벗어나더라도 일정 수준의 품질을 가진 액상의 광물 용해액을 제조하는 데에 문제가 없는 것이라면 본 발명의 범위에 포함되는 것으로 이해해야 할 것이다.In the preparation of the stabilized mineral solution, the mixing ratio of mineral solution: sodium silicate solution: borax: potassium citrate: iron salt is approximately 80 to 96.9: 0.1 to 5: 0.1 to 5: 0.1 to 5 based on volume and weight. : 0.1 to 5 ratio, more preferably 91 to 99.2: 0.2 to 2: 0.2 to 2: 0.2 to 2: 0.2 to 3, most preferably 99: 0.2: 0.2: 0.2: 0.4 do. Of course, there is no problem inherent functionality except that the functionality is slightly lowered even if the composition is outside this range, the composition of the mineral solution of the present invention is not limited to the above-mentioned range, even if slightly out of the range of the composition ratio of a certain level It is to be understood that the present invention is included in the scope of the present invention as long as there is no problem in preparing a liquid mineral solution having high quality.
이와 같은 방식으로 제조된 본 발명에 따른 광물 용해액의 혼합물은 원적외선을 방사하는 세라믹이나 광석이 가지는 본래의 기능을 상온 액체 상태에서도 아주 적은 에너지를 사용하여 수행할 수 있다. 이와 같은 철염을 함유하는 액상의 원적외선 방사체는 충분히 희석한 상태에서도 전기수의 성질을 지니며 물분자의 결합 집단이 작은 액체로서 알칼리수(pH 약 8.2)에 해당한다. The mixture of the mineral solution according to the present invention prepared in this way can perform the original function of the ceramic or ore that emits far infrared rays using very little energy even at room temperature liquid state. The liquid far-infrared emitter containing iron salts has the properties of electric water even in a sufficiently diluted state and corresponds to alkaline water (pH about 8.2) as a liquid having a small binding group of water molecules.
본원 발명의 광물 용해액은 중금속이나 환경 유해 물질을 거의 함유하고 있지 않아서 인체나 동물 및 주위 환경에 전혀 악영향을 미칠 우려가 전혀 없음을 알 수 있다. 상기 용해액은 목적하는 바의 용도에 따라 최고 200 배까지 희석하여 다양한 용도로 사용하는 것이 가능하다. It can be seen that the mineral solution of the present invention contains almost no heavy metals or environmentally harmful substances, so that there is no fear of adversely affecting the human body, the animal, and the surrounding environment. The solution can be used for various purposes by diluting up to 200 times depending on the intended use.
본 발명의 화장료 조성물에 있어서 두 번째 주요 성분은 천연 식물 추출물을 포함한다. The second main ingredient in the cosmetic composition of the present invention comprises a natural plant extract.
이러한 한약재 추출물은 녹두, 오미자액, 오이, 천문동, 작약, 가시오가피, 숙지황, 녹용, 황정, 백봉령, 당귀, 율무, 감초, 상백피, 은행잎, 영지버섯, 율피로 이루어진 군 중에서 선택된 하나 이상의 성분을 포함한다.These herbal extracts include one or more components selected from the group consisting of mung bean, Schisandra chinensis, cucumber, Astronomical dong, Peony, thorny ogapi, Sukjihwang, antler, yellowfin, baekbongryeong, tangwi, yulmu, licorice, sangbaekpi, ginkgo leaf, ganoderma lucidum .
상기 성분 중 녹두 추출물은 미백기능 외에 해독 작용과 피부의 탄력성을 유지시켜 준다. Mung bean extract of the above ingredients maintains the detoxification and elasticity of the skin in addition to the whitening function.
녹두(Phaseolus aureus, Phaseolus radiatus, Mung bean)는 쌍떡잎식물 장미목 콩과의 한해살이 풀로서, 프로비타민 A(0.22mg%), B1(0.53mg%), B2(0.12mg%,) PP(1.8mg%) 등과 녹말(66%), 펜토산, 갈란탄, 포도당, 라피노오스, 사탕, 덱스트린 등의 탄수화물과 단백질이 풍부하다. 따라서 녹두는 혈액 순환을 돕고 청량감을 주는 세안제, 모공 청결, 피지분비 원활, 미백 박용 및 지성 여드름 피부에 효과가 높다. 녹두를 곱게 갈아서 물에 이겨 마사지 하면 피부에 지질이 제거되어 여드름과 주근깨에도 효과가 있으며 소아 피부염에도 좋은 작용을 한다. 녹두의 유효 성분을 개별적으로 추출하는 경우에는 이를 분말화한 다음, 알코올 등을 사용한 통상의 유기 용매 추출법에 의해 추출할 수도 있다. Mung bean ( Phase of Phaseolus aureus, Phaseolus radiatus , Mung bean) is a perennial herb of the dicotyledonous plant Rosaceae, Provitamin A (0.22mg%), B1 (0.53mg%), B2 (0.12mg%,) PP (1.8mg%) Abundant carbohydrates and proteins such as starch (66%), pentosan, galantan, glucose, raffinose, candy, and dextrin. Therefore, green beans are good for cleansing cleansing, pore clean, sebum secretion, whitening, oily acne and skin acne. Grind the mung beans finely and massage them with water to remove lipids from the skin, which is effective for acne and freckles, and also works well for pediatric dermatitis. When the active ingredient of mung bean is extracted separately, it may be powdered and then extracted by a conventional organic solvent extraction method using alcohol or the like.
본 발명의 기능성 화장료 조성물에 있어서, 오미자액은 피부에 유연성을 제공하는 성분으로 첨가될 수 있다.In the functional cosmetic composition of the present invention, Schizandra chinensis solution may be added as a component that provides flexibility to the skin.
오미자는 혈압강하 및 진해 거담작용을 갖고 있어서 한약재로 널리 이용되고 있을 뿐 아니라 위액 분비의 조절 및 담즙분비 촉진작용을 갖고 있어서 건강 식품의 성분으로 널리 이용되고 있다. 특히 오미자는 단맛, 쓴맛, 신맛, 매운맛, 짠맛 등이 복합된 특이한 맛을 갖고 있으며 고유의 특이한 향을 나타내므로 다류와 주정 음료의 원료로도 이용되고 있다. 오미자는 분쇄한 후에 물 또는 알코올로 추출할 수 있다. 또한 수증기 증류하여 추출하는 것이 더욱 바람직한 결과를 초래할 수 있다.Schisandra chinensis has a blood pressure lowering and antitussive expectorant action, which is not only widely used as a herbal medicine but also has a function of controlling gastric secretion and promoting bile secretion. In particular, Schisandra chinensis has a unique taste that combines sweetness, bitterness, sourness, spicy taste, salty taste, etc., and it is also used as a raw material for teas and spirit drinks. Schisandra chinensis can be milled and then extracted with water or alcohol. In addition, extraction by steam distillation may result in more desirable results.
본 발명의 기능성 화장료 조성물에 있어서, 오이 추출물은 보습 및 진정효과를 나타내는 추가의 성분으로 첨가할 수 있다.In the functional cosmetic composition of the present invention, the cucumber extract may be added as an additional component exhibiting a moisturizing and soothing effect.
오이의 주요 성분은 약 95%가 수분이며, 단백질, 지질, 당질의 함량이 낮아 칼로리는 매우 낮고, 그 밖에 칼륨, 비타민 A와 비타민 C를 함유하고 있다. 또한 오이에 함유된 칼륨은 과잉의 염분을 체외로 배출시키는 작용을 하며, 이뇨작용을 촉진시켜 신장병 환자나 고혈압 환자에게 좋다고 알려져 있다. 또한 오이는 목이 마르고 아플 때, 특히 더위를 먹었을 때 섭취하면 좋다고 알려져 있다. 오이는 특별한 추출법에 의해 추출할 필요는 없고, 즙을 내어 사용할 수 있다. 오이를 미세하게 간 다음 여과지(Wattman NO.2)를 사용하여 여과하고 0.45㎛ 필터를 이용(미생물 제거 목적)하여 최종 여과하여 사용한다. Cucumbers are about 95% water, low in calories, low in protein, lipids and sugars, and potassium, vitamin A and vitamin C. In addition, the potassium contained in cucumber acts to discharge excess salt into the body and promotes diuretic action, which is known to be good for patients with kidney disease or hypertension. Cucumbers are also known to be good when you're thirsty and sick, especially when you're in the heat. Cucumber does not need to be extracted by a special extraction method, it can be used juiced. Finely chop the cucumber, filter using filter paper (Wattman NO.2), and use the final filtration using a 0.45 μm filter (for microbial removal).
천문동(天門冬, Asparagus cochinchinensis(Lour.)Merrill)은 나리과 (Liliaceae)에 속하는 다년생 초본(草本)으로, 한국이나 중국의 남부 해안지역 산 기슭에서 야생하며 가을에서 겨울사이에 덩이뿌리를 채취하여 증기로 쪄서 외피를 제거한 것을 약재로 사용한다. 약재는 약간 특이한 냄새가 조금 있고 맛은 말며 약간 쓰다. 천문동 추출액은 세절한 다음, 분쇄물 건조중량에 대하여 3~20배 부피의 물이나 탄소수 1-4개의 저급 알코올로 추출하여 제조할 수 있다. Asparagus cochinchinensis (Lour.) Merrill is a perennial herb that belongs to the Liliaceae family . The outer skin is removed as a medicine. The medicinal herbs have a little peculiar smell and taste slightly bitter. The astronomical extract can be prepared by cutting it and then extracting it with 3-20 times the volume of water or 1-4 lower alcohols.
작약(Paeonia albiflora Pallas)은 미나리아재비과(Ranunculaceae)에 속하는 작약의 뿌리를 건조 분말화한 것으로서 원주상 내지 원추상으로서 길이 7~20 cm, 지름 10~25 cm이며 큰 것은 세로로 쪼갠 것도 있다. 바깥 면은 갈색 내지 엷은 회갈색으로서 세로주름이 뚜렷하고 측근이 붙어있던 자리와 가로의 피복이 있으며 때로는 왼쪽 끝에 움푹한 줄기의 자국이 있다. 꺾은 면은 가루상이고 치밀하여 확대경으로 보면 회갈색이고 목부에는 엷은 갈색의 방사선이 있다. 이 약은 특이한 향기가 있으며 맛은 처음에는 달고 나중에는 약간 떫고 쓰다. 패오니플로린(Paeoniflorin), 패오닌(Paeonine), 벤조산, 탄닌, 알비플로린(Albiflorin)이 구성 성분으로 알려져 있고, 항염증작용, 항균작용, 살균작용, 소염작용, 미백, 보습작용, 멜라닌 색소 생성 억제작용, 여드름 예방 및 치료에 효능이 있으며, 소염작용과 진통작용이 있으며 기미, 주근깨, 여드름이나 거친 피부를 치유하는 효과가 있다고 알려져 있다. 작약은 3~10배량의 물로 추출하는 것이 좋다.Peony ( Paeonia albiflora Pallas ) is a dry powdered root of peony belonging to the Ranunculaceae family, columnar to conical, 7-20 cm long, 10-25 cm in diameter, with large ones. The outer surface is brown to light grayish brown with clear vertical wrinkles, abutments and transverse coverings, and sometimes a dent on the left end. Folded face is powdery, dense, grayish brown in magnifier, light brown neck. The drug has an unusual scent and tastes sweet at first and slightly steamed and bitter later. Paeoniflorin, Paeonine, Benzoic acid, Tannin, Albiflorin are known as constituents, anti-inflammatory, antibacterial, bactericidal, anti-inflammatory, whitening, moisturizing, melanin pigment production It is effective in inhibiting, preventing and treating acne, has anti-inflammatory and analgesic effects, and is known to cure spots, freckles, acne or rough skin. Peony should be extracted with 3 ~ 10 times of water.
가시오가피는 두릅나무과(Araliaceae)의 낙엽 관목인 자오가(Acanthopanax senticosus (RUPR. et MAXIM) HAR MS)의 뿌리와 근경 및 수피를 건조한 것으로서 카로틴(carotene), 리구스트린(ligustrin), 7-메틸-6,8-디메틸쿠마린글리코사이드 (7-methyl-6,8-dimethylcoumarineglycoside), 갈락토사이드(galactoside), 및 카리오피놀(caryophyllenol) 등 다종의 배당체와 플라본(flavone), 정유, 다당 등을 성분으로 함유한다. 현재까지 밝혀진 가시오가피의 약리 작용으로는 진정작용, 항스트레스작용, 면역증강작용, 평활근 이완작용, 소염작용, 류마치스성 등이 보고되어 있으며, 또한, 가시오가피는 정신적 육체적 활력을 불어넣으며 강장 효과 및 비특이적인 저항력 증가를 나타내어 질병에 대한 예방효과가 있으며, 혈당저하 작용, 암, 저혈압에도 효과가 있으며 사람을 흥분시키지 않기 때문에 인삼과는 달리 불면증 등의 부작용이 없다고 알려져 있다(Loydia, Vol. 32. 1, 1969). 본 발명에 따른 가시오가피 추출물은 단독으로 추출하는 경우에는 물이나 통상의 유기 용매 추출에 의해 통상의 방식으로 얻을 수 있다.Gasiohgapi is carotene (carotene), Liguria Stryn (ligustrin) as the dried root and rhizome and bark of the deciduous shrub of Araliaceae of Zhao (Araliaceae) (. Acanthopanax senticosus ( RUPR et MAXIM) HAR MS), 7- methyl- It contains various glycosides such as 6,8-dimethylcoumarineglycoside, galactoside, and caryophyllenol, flavones, essential oils and polysaccharides. It contains. The pharmacological effects of psoriasis that have been discovered to date have been reported to be sedative, antistress, immune enhancing, smooth muscle relaxation, anti-inflammatory, rheumatoid, etc. In addition, psoriasis induces mental and physical vitality, tonic effect and nonspecific It is known to have an increased resistance to prevent diseases, prevent hypoglycemia, cancer, hypotension and have no side effects such as insomnia unlike ginseng because it does not excite people (Loydia, Vol. 32. 1, 1969). The extract of prickly pear extract according to the present invention can be obtained in a conventional manner by extraction with water or a conventional organic solvent when extracted alone.
지황(Rehmannia glutinosa)은 중국이 원산지이고 꽃은 6∼7월에 붉은 빛이 강하면서 연자주색으로 되고 이것은 식용 식물로써 대개 뿌리를 사용하며 보통 한방에서는 생것은 생지황, 쪄서 말린 것은 숙지황(熟地黃)이라고 한다. 지황에는 만디트, 당, 카르텐, 사이토스테롤, 비타민 A 등이 함유되어 있으며 대체로 해열, 지열, 강심, 보혈 및 자양 강장 등 보약제로 널리 이용되는 한약 중 하나이다. 숙지황은 3~10배량의 물로 추출하는 것이 좋다. Rehmannia glutinosa is native to China and the flowers are reddish purple with strong red light from June to July. This is an edible plant that usually uses roots. Raw herbs are usually raw, and dried and ripened sulfur is mature. It is called. It is one of the most widely used herbal medicines such as antipyretic, geothermal, cardiac, blood and nourishing tonic, including mandite, sugar, karten, cytosterol and vitamin A. Sukji sulfur is good to extract 3 to 10 times the amount of water.
녹용(Cervi Parvum Corun)은 사슴과(Cervidae)에 속하는 매화록(Cervus Nippon Temminck Var. Mantcharicus Swinhoe), 마록(Cervus elaphus L.) 또는 기타 종의 골질화 안된 어린 뿔을 채취하여 건조한 것으로, 예로부터 우수한 보혈강장제로 알려져 왔다. 동의보감 등의 문헌에도 녹용은 강장작용, 보기혈작용, 강정작용, 진통작용, 생장발육촉진 작용, 심부전증 치료 작용 및 기능항진 작용 등이 있으며, 피로회복, 신체활력증강 및 신장의 이뇨기능강화 효과 등 많은 효능을 갖고 있는 것으로 알려져 있다. 녹용 추출액을 단독으로 제조할 경우에는 이를 잘게 분쇄한 후 물을 용매로 하여 가열 추출하거나 또는 세절한 녹용에 약 5배수의 희석 알코올을 침지시켜 1~2 주간 상온에서 방치하여 녹용액이 우러나오게 하여 녹용 추출액을 제조한다.Deer Antlers ( Cervi Parvum Corun ) are dried and harvested unhorned young horns of the Cervus Nippon Temminck Var.Mantcharicus Swinhoe, Cervus elaphus L. or other species belonging to the family Cervidae . It has been known as an excellent blood tonic. In the literature such as Dongbogam, deer antler has tonic action, view blood action, gangjeong action, analgesic action, growth growth promotion action, heart failure treatment action and hyperactivity action, fatigue recovery, physical vitality and kidney diuretic effect, etc. It is known to have a lot of efficacy. When the antler extract is prepared alone, it is finely pulverized and then extracted by heating with water as a solvent or by dipping about 5 times of dilute alcohol in fine antler to leave the rust solution at room temperature for 1 to 2 weeks. Prepare an antler extract.
황정(Polygonatum falcatum A. Gray)은 백합과에 속하는 다년생초본인 진황정의 근경(根莖)을 건조한 것으로 일명 선인여량(仙人餘糧)이라고도 일컬어지며 무독, 감미를 가지고 있고 자양강장제로서 오장을 편안하게 하고, 바람과 습기를 제하며 몸을 가볍게 하고 정기와 골수를 메우며 노화현상을 방지하고 오로칠상(五老七傷)을 보호하며 비장과 위장에 이롭고 심장과 폐를 윤택하게 하며 근골(筋骨)을 강하게 하고 추위, 더위를 견디게 하며, 허약함을 보하는 등 보약중의 으뜸가는 상약이라고 전하고 있는 건강한약재이다. 황정은 단독으로 추출할 경우에는 물 및 에탄올 드의 유기용매를 이용한 통상의 방식으로 추출할 수 있다.Hwangjeong ( Polygonatum falcatum A. Gray) is a dried perennial herbaceous perennial herbaceous ginseng root, also known as Suninyeo (량 人 餘糧), has a non-toxic, sweet taste and comforts the five intestines. It removes wind and moisture, lightens the body, replenishes regular bones and bone marrow, prevents aging, protects Orochill, protects the spleen and stomach, makes the heart and lungs healthy, strengthens the musculature. It is a healthy medicine that is said to be the foremost drug in the medicine, such as to endure cold and heat, and to weaken the weakness. When yellow gold is extracted alone, it can be extracted in a conventional manner using an organic solvent of water and ethanol.
백봉령(白茯笭)은 송수를 벌채한 후 5~9년을 경과한 토중잔근에 기생하는 균체이며, 옛부터 기미 등 색소 침착을 없애는 민간요법으로 많이 이용되어 왔다. 다당류, 유기산, 단백질, 비타민D, 레시틴, 아데닌, 콜린, 과당, 무기질 등이 많이 함유되어 있어 피부를 맑고 윤기 있게 한다. 백봉령은 3~10 배량의 물로 추출하는 것이 좋다. Baekbong-ryong (白 茯 笭) is a cell parasitic in the soil roots 5 to 9 years after harvesting the water, and has been widely used as a folk remedy to remove pigmentation such as spots. Polysaccharides, organic acids, proteins, vitamin D, lecithin, adenine, choline, fructose, minerals, etc. are contained in the skin to make it clear and shiny. Baekbongryeong should be extracted with 3 ~ 10 times of water.
당귀는 쌍떡잎식물 이판화군 산형화목 미나리과의 여러해살이풀로서 진통,배 농(排膿), 지혈, 강장 작용이 있으므로 복통 종기 타박상 및 부인병에 이용되고 있다. Angelica is a perennial herb of the dicotyledonous plant, an anhydraceae family, and is used for pain, pear abscess, hemostasis, and tonic.
율무는 의주자, 인미, 의미(薏米)라고도 하며, 외떡잎식물 벼목 화본과의 한해살이풀이다. 종자를 의이인(薏苡仁)이라고 하는데, 차 등으로 먹거나 이뇨, 진통, 진경, 강장작용이 있으므로 부종, 신경통, 류머티즘, 방광결석 등에 약재로 쓴 다. 생잎은 차 대용으로 쓰고 뿌리를 황달과 신경통에 쓴다. 줄기에 달린 잎은 사료로도 쓴다. 율무 가루를 사용하여 적당한 자극을 주면 피부 표면의 묵은 각질이나 모공에 쌓인 때를 벗겨 낼 수 있으며, 피부의 신진 대사를 높여 주고 짧은 시간 내에 피부재생효과가 뛰어나 기미, 주근깨, 거친 피부, 여드름 등의 피부 트러블에 큰 효과가 있다.Yulmu is also known as Uiju, Inmi, and Sei-in. Seeds are called Euiin (薏苡仁), or eat as tea or diuretic, analgesic, jingyeong, tonic, so edema, neuralgia, rheumatism, bladder stones, etc. are used as medicine. Raw leaves are used as tea substitutes and roots are used for jaundice and neuralgia. The leaves on the stems are also used as feed. If you use it, you can remove the dead skin on the surface of dead skin and pores, and you can improve the metabolism of the skin and regenerate the skin within a short time. It has a great effect on skin troubles.
감초는 쌍떡잎식물 장미목 콩과의 여러해 살이풀로, 감초에 있는 글리시리친은 피부를 진정시키는 데 효과가 있으며, 풍부한 플라노보이드는 혈관을 튼튼하게 한다. 소염 작용이 뛰어나고, 진정 작용과 상처를 치료하는 효과도 있어 민감성 피부와 여드름 치료에 탁월하다.Licorice is a perennial plant of the dicotyledonous rosemary legume. Glycyrrhicin in licorice is effective for soothing the skin. Abundant flavonoids strengthen blood vessels. It is excellent for anti-inflammatory skin and acne because it has an excellent anti-inflammatory effect, and also has a sedative and healing effect.
상백피는 뽕나무뿌리를 말하는 것으로, 뽕나무 뿌리 껍질의 코르크 층을 제거한 비늘 같은 껍질이다. 상백피는 자외선흡수 작용, 항티로시나제 작용, 자동산화 억제 작용 등의 미백 작용과 항균, 항염 작용, 보습, 진정 작용, 노화방지작용, 항알러지 작용 및 항바이러스 작용에 뛰어나다.Morus bark refers to the mulberry root, which is a scale-like bark that removes the cork layer of the mulberry root bark. Epidermis is excellent in whitening, antibacterial, anti-inflammatory, moisturizing, soothing, anti-aging, anti-allergic and antiviral activity.
은행잎은 종자(열매)는 식용하는데, 한방에서는 종자를 백과(白果)라 하여 해수, 천식, 유정(遺精), 소변백탁(小便白濁), 자양(滋養) 등에 처방하여 복용한 다. 수피(樹皮)를 백과수피라 하고 뿌리를 백과근이라 하여 관상동맥경화, 흉통, 심장통, 심계(心悸), 고혈압, 천식, 해수 등에 처방한다. 최근에는 은행 잎에서 혈행개선이나 심장병 치료약의 성분을 추출하여 이용하고 있다. Ginkgo biloba is a seed (fruit) is edible, but in one shot, the seeds are encyclopaedia (白果) is called seawater, asthma, oil well (遺精), urine white cloud (小便 白濁), nourishment (滋養) and take. The bark (樹皮) is called encyclopedia and the root is called encyclopaedia, coronary arteriosclerosis, chest pain, heart pain, heart system, high blood pressure, asthma, sea water and so on. Recently, ginkgo biloba has been used to extract components of blood circulation improvement and heart disease drugs.
영지 버섯은 불로초라고도 하며, 담자균류 민주름목 구멍장이버섯과의 버섯이다. 갓과 자루 표면에 옻칠을 한 것과 같은 광택이 있는 1년생 버섯이다. 한방에서는 강장, 진해, 소종(消腫) 등의 효능이 있어 신경쇠약, 심장병, 고혈압, 각종 암종에 사용한다.Ganoderma lucidum mushroom, also called Bulchocho, is a mushroom of the fungus fungus Democratic grove. It is a year-round mushroom that has a gloss like lacquer on its lampshade and bag surface. In oriental medicine, tonic, Jinhae, small swelling (효능) and the efficacy, such as nervous breakdown, heart disease, high blood pressure, various cancers are used.
율피는 밤의 속껍질을 말려서 쓰는 것으로, 옛부터 노화 피부나 기미 피부에 효과가 커 민간 요법에 많이 이용돼 왔으며, 무엇보다 탄닌 성분이 풍부해 모공이 크고 지성인 피부에 사용하면 탁월한 효과를 갖는다.Yulpi is used to dry the skin of chestnut, and it has been used for folk remedies due to its effects on aging skin and blemishes from the old days. Above all, it is rich in tannin, which is excellent when used on large and oily skin with pores.
위와 같은 추가의 식물 추출물은 단독으로 추출하는 경우에는 물이나 통상의 유기 용매 추출법 또는 그 분야에서 잘 알려진 통상의 추출법에 의해 얻을 수 있다.Additional plant extracts as described above can be obtained by water or conventional organic solvent extraction methods or by conventional extraction methods well known in the art when extracted alone.
본 발명에 따른 한방 조성물 중 식물 기능성 추출물은 각 재료별로 추출하는 것이 더욱 효율적이고, 이들의 유효 성분을 각각 추출하는 방식은 잘 알려진 방법으로 수행하여 각 추출물을 적절한 혼합비로 합하여 목적하는 조성물을 제조하는 것이 더욱 바람직하나, 경우에 따라서는 이를 한꺼번에 처리하는 것이 시간을 절약할 수 있다. 따라서, 한꺼번에 처리하는 경우에는 각 재료를 깨끗이 세척하고 이를 세절한 다음, 합하여 먼저 에탄올 등의 유기 용매로 추출한 다음 유기용매에 용해되는 성분을 1차로 추출하고, 이 추출하고 남은 추출박(抽出粕)에 약간 낮은 농 도(예를 들면, 20~70%)의 에탄올 등의 유기 용매로 2차 추출하여 유기 용매와 물에 용해되는 잔류 유효 성분을 추출한 다음 마지막으로 1,2차 추출하고 난 추출박을 물로만 3차 추출하여 물에만 용해되는 성분을 추출함으로써 물 및 유기 용매에 용해되는 성분들을 모두 추출한다. 추출 온도는 30~100 ℃에서, 추출 시간은 1 시간 내지 1주일, 경우에 따라서는 상온에서 6개월 정도 지속될 수 있다. 용매의 함량은 부피비로 3~20배로 사용하는 것이 좋다.Plant functional extract of the herbal composition according to the present invention is more efficient to extract by each material, the method of extracting each of their active ingredients is carried out by a well-known method to combine the respective extracts in an appropriate mixing ratio to prepare the desired composition It is more preferable, but in some cases, processing them all at once can save time. Therefore, in the case of treatment at once, each material is washed cleanly, and then chopped, and then combined, first extracted with an organic solvent such as ethanol, and then first extracted with a component dissolved in an organic solvent, the extracted extraction foil (抽出 粕) Second extraction with an organic solvent such as ethanol at a slightly low concentration (for example, 20 to 70%) to extract residual active ingredients dissolved in organic solvents and water, and finally the first and second extraction By tertiary extraction only with water to extract the components dissolved only in water to extract all the components dissolved in water and organic solvents. The extraction temperature can be maintained at 30 ~ 100 ℃, extraction time is 1 hour to 1 week, in some cases at room temperature for about 6 months. The solvent content is preferably used 3 to 20 times by volume.
본 발명에 따르는 조성물에서 성분의 조성비율은 다양한 실험 결과에 의하면 조성물의 성분을 원료의 중량을 기준으로 광물 용해액: 천연 식물 추출액을 0.1~99.9:99.9~0.1중량%의 범위 내에서 적절히 조정하여 사용한다. 바람직하게는, 2~98:98~2중량%로 포함하는 것이 좋다. 특히, 광물질 용해액 5%~98%: 각각의 생약 추출물 0.1~5%로 배합하는 것이 가장 바람직한 결과를 초래할 수 있다.The composition ratio of the component in the composition according to the present invention according to various experimental results according to the weight of the raw material of the mineral dissolution solution: natural plant extracts by appropriately adjusting within the range of 0.1 to 99.9: 99.9 to 0.1% by weight use. Preferably, it is good to contain in 2 to 98: 98-2 weight%. In particular, 5% to 98% mineral solution: 0.1 to 5% of each herbal extract can produce the most desirable results.
위와 같은 조성비는 각각의 생약성분이 갖는 유효량과 부작용 등을 고려하여 설정한 것이며, 그 비율의 범위를 벗어나는 경우에는 효과가 떨어질 우려가 있다. The above composition ratio is set in consideration of the effective amount and side effects of each herbal ingredient, if there is a range outside of the ratio there is a fear that the effect is reduced.
물론 상기 조성이 이러한 범위를 벗어나더라도 기능성이 다소 낮아지는 것 외에는 본질적인 기능성의 문제는 없으므로 본 발명의 식물 추출액의 조성은 상기한 범위에만 한정되는 것이 아니며 상기 조성비의 범위에서 다소 벗어나더라도 일정 수준의 품질을 가진 식물 추출액을 제조하는 데에 문제가 없는 것이라면 본 발명의 범위에 포함되는 것으로 이해해야 할 것이다.Of course, even if the composition is out of this range, there is no problem inherent functionality except that the functionality is somewhat lowered, the composition of the plant extract of the present invention is not limited to the above-mentioned range, even if somewhat out of the range of the composition ratio of a certain level of quality If there is no problem in preparing a plant extract having a will be understood to be included in the scope of the present invention.
상기 성분들은 화학 합성제가 아닌 천연 물질의 추출물을 포함하고 있으므로 후술하는 실시예 및 시험예의 결과로부터 잘 알 수 있는 바와 같이 피부에 대한 자극성이나 독성이 없어서 안정성이 우수하며, 피부미백 등에 탁월한 효과를 갖고 있을 뿐만 아니라 피부에 대한 보습 효과가 있어서 피부 촉감 개선 및 지방 성분을 제거하는 등의 기능성이 있으므로 이러한 기능성을 요하는 화장품의 성분으로 사용될 수 있다. 뿐만 아니라 음이온을 방출하여 피부를 활성화시키고, 인체의 신진 대사를 촉진하며 미네랄을 보충하는 기능을 갖는다. Since the components contain extracts of natural substances, not chemical synthetic agents, as can be seen from the results of the following Examples and Test Examples, there is no irritation or toxicity to the skin, so the stability is excellent, and the skin whitening effect is excellent. As well as having a moisturizing effect on the skin, such as improving the skin feel and removing fat components can be used as a component of a cosmetic requiring such functionality. In addition, it releases negative ions to activate the skin, promote the body's metabolism and supplement minerals.
본 발명의 화장료 조성물은 그 제형에 있어서 특별히 한정되는 바가 없으며, 예를 들면, 유연화장수, 수렴화장수, 영양화장수, 아이크림, 영양크림, 마사지크림, 클렌징크림, 클렌징 폼, 클렌징 워터, 파우더, 에센스, 팩 등의 제형으로 제조하여도 좋다.The cosmetic composition of the present invention is not particularly limited in the formulation, for example, supple cosmetics, astringent cosmetics, nourishing cosmetics, eye cream, nutrition cream, massage cream, cleansing cream, cleansing foam, cleansing water, powder, essence Or a formulation such as a pack.
상기 화장품의 제형은 화장품 제조 분야에서 잘 알려진 통상적인 방법에 의해 제조할 수 있다. Formulations of the cosmetics may be prepared by conventional methods well known in the cosmetic manufacturing field.
상기한 바와 같은 기능성 화장품들은 목적하는 기능성을 더욱 향상시키기 위한 보조 성분으로서, 이들에 한정되지 않고, 쌀눈, 쌀겨, 미역 분말, 다시마 분말, 죽염, 쌀겨, 해조류 분말, 대나무 숯 등을 적당량으로 배합하여 기능성을 더욱 증대시킬 수 있다. Functional cosmetics as described above are not limited to these as an auxiliary component to further improve the desired functionality, by combining an appropriate amount of rice snow, rice bran, seaweed powder, kelp powder, bamboo salt, rice bran, seaweed powder, bamboo charcoal, etc. Functionality can be further increased.
이러한 보조 성분이 단독 또는 혼합하여 첨가되는 경우에 이들의 첨가량은 전체 조성물의 중량을 기준으로 0.1 ~ 10 중량%로 배합하여 사용하는 것이 적합하다.When these auxiliary components are added alone or in combination, their addition amount is suitably used in an amount of 0.1 to 10% by weight based on the total weight of the composition.
이들 화장품의 부형제로서는 사용 목적에 따라 달라질 수 있으나, 일반적으로 글리세린, 부틸렌글리콜, 프로필렌글리콜, 알코올류 등의 방부제 또는 식물성 방부제, 정제수, 보습제, 벌크화제, 크림제, 계면활성제, pH 조정제, 향료 등을 적량 혼합하여 원하는 제형의 형태에 따라 제조하는 것이 바람직하다. 또한 안정화제, 용해화제, 비타민, 안료 및 향료와 같은 통상적인 보조제, 그리고 담체를 포함할 수 있다.Excipients of these cosmetics may vary depending on the purpose of use, but are generally preservatives such as glycerin, butylene glycol, propylene glycol, alcohols or vegetable preservatives, purified water, moisturizers, bulking agents, creams, surfactants, pH adjusters, flavorings It is preferable to prepare according to the form of the desired formulation by mixing a suitable amount. It may also include conventional adjuvants such as stabilizers, solubilizers, vitamins, pigments and flavorings, and carriers.
본 발명의 기능성 화장료 조성물은 피부에 직접 접촉하여 위생적으로 사용되는 일회용 제품, 예를 들면, 일회용 물티슈 제품, 마사지 팩, 일회용 물수건, 유아용 물티슈 등의 제형으로 제조하여도 좋다.The functional cosmetic composition of the present invention may be prepared in the form of a disposable product, such as a disposable wet tissue product, a massage pack, a disposable wet towel, a baby wipe, or the like, which is used hygienically in direct contact with the skin.
따라서, 본 발명은 다른 일면에 있어서 상기 기능성 화장료 추출물을 포함하는 것을 특징으로 하는 일회용 위생제품을 제공한다. 이러한 일회용 제품은 상기의 식물 추출액을 포함하는 한방 화장료 조성물을 적절한 비로 희석하여 이를 통상의 방식으로 정제수, 보습제, 계면활성제, pH 조정제, 식물성 방부제, 향료 등을 적량 혼합하여 이를 부직포나 순면, 스판레이스, 펄프 등에 흡수시켜 통상적인 방식으로 제조할 수 있다.
Accordingly, the present invention provides a disposable hygiene product comprising the functional cosmetic extract in another aspect. Such disposable products may be diluted in an appropriate ratio of the herbal cosmetic composition containing the plant extract in a suitable ratio and mixed with a suitable amount of purified water, moisturizers, surfactants, pH adjusters, vegetable preservatives, fragrances, etc. It may be absorbed into pulp or the like and prepared in a conventional manner.
<실시예><Example>
이하, 실시예에 의하여 본 발명의 기능성 화장료 조성물에 관하여 더욱 상세하게 설명하나, 이들은 본 발명을 설명할 목적으로 제시된 것이며 어떠한 식으로도 본 발명을 제한하려고 의도한 것은 아니다.
Hereinafter, the present invention will be described in more detail with reference to the functional cosmetic composition of the present invention, but these are presented for the purpose of illustrating the present invention and are not intended to limit the present invention in any way.
실시예 1: 광물 용해액의 제조Example 1: Preparation of Mineral Dissolving Solution
구매한 몽골산 토르말린(판매원: 토르말린코리아(주) 5kg을 자동세척기로 깨끗하게 수세하여 모래, 오물 등의 이물질을 제거하여 건조시킨 다음 분쇄기에서 분쇄시켰다. 이 전처리된 토르말린 분말에 정제수 또는 하기 표 1의 조성에 나타낸 용해 보조제를 사용하여 120 ℃의 온도에서 3시간 동안 교반 하에 숙성시킴으로써 토르말린 용해액을 얻었다. 용해 보조제인 수산화칼륨 용액은 류수 1000ml과 수산화칼륨 420g을 혼합하여 제조하고, 탄산칼륨 용액은 증류수 1000ml과 탄산칼륨을 420g을 혼합하여 제조하였다.Mongolian tourmaline (Sales: Tourmaline Korea Co., Ltd.) was washed with an automatic washing machine to remove foreign substances such as sand and dirt, and then dried in a pulverizer. Purified water or purified water in the pretreated tourmaline powder A tourmaline solution was obtained by aging under stirring at a temperature of 120 ° C. for 3 hours using a dissolution aid indicated in the composition, a solution of potassium hydroxide as a dissolution aid was prepared by mixing 1000 ml of water and 420 g of potassium hydroxide, and a potassium carbonate solution was distilled water. 1000 ml and potassium carbonate were prepared by mixing 420 g.
마찬가지로 제올라이트(Clinoptilolite-(Na2, Ca) Al2Si7O18·6H 20, 대신에 Mordenite-Na2 (AlSi5)12)2·7H20를 사용해도 좋음) 용해액을 제조하였다.Similarly, a solution of zeolite (Clinoptilolite- (Na 2 , Ca) Al 2 Si 7 O 18 · 6H 2 0, instead of Mordenite-Na 2 (AlSi 5 ) 12 ) 2 · 7H 2 0) was prepared.
실시예 2: 안정화 용해 혼합물의 제조Example 2: Preparation of Stabilized Dissolution Mixtures
상기 실시예 1에서 제조된 각각의 용해액과, 규산소다 용액(Na2O·nSiO2-xH2O), 붕사(Na2B4O7) 및 구연산칼륨(K2C6 H5O7), 황산제1철, 산화제2철(Fe2O3)을 하기 표 2에 기재된 함량으로 혼합하여 80 ℃에서 약 30분 동안 교반하에 숙성시킴으로 써 본 발명의 액상의 광물 용해 혼합물을 얻었다. The embodiment of each solution was prepared in Example 1 and a sodium silicate solution (Na 2 O · nSiO 2 -xH 2 O), borax (Na 2 B 4 O 7) and potassium citrate (K 2 C 6 H 5 O 7 ), Ferrous sulfate and ferric oxide (Fe 2 O 3 ) were mixed to the contents shown in Table 2 and aged at 80 ° C. for about 30 minutes with stirring to obtain a liquid mineral dissolution mixture of the present invention.
실시예 3: 식물 추출물의 제조Example 3: Preparation of Plant Extract
녹두, 오미자, 천문동, 가시오가피, 녹용, 황정, 율피를 각각 500 g 씩 준비한 다음 이를 세절하고 분말화하여 5 배량의 알코올을 첨가하여 80 ℃의 온도에서 5시간 동안 추출하였다. 마찬가지로 작약, 숙지황, 백봉령, 영지버섯, 감초, 은행잎, 당귀, 율무, 상백피를 각각 500 g 씩 준비한 다음 이를 세절하고 분말화하여 5배량의 물을 첨가하여 80 ℃의 온도에서 5시간 동안 추출하였다. 오이 500 g을 착즙한 다음 상기 추출물을 모두 합하였다. 상기 추출후 남은 찌거기를 재차 에탄올(95%)을 5배량 첨가하여 동일한 방식으로 재차 추출하고, 남은 추출박(抽出粕)에 50% 농도의 에탄올로 재차 추출하였다. 잔류 추출물에 대하여 5 배량의 물로만 3차 추출하여 물에만 용해되는 성분을 추출함으로써 물 및 유기 용매에 용해되는 성분들을 모두 추출하여 각 추출물들을 합하였다. 추출 온도는 30~100 ℃에서, 추출 시간은 1 시간 내지 1주일, 경우에 따라서는 상온에서 6개월 정도 지속시켰다. 용매의 함량은 대체적으로 5배수의 부피비로 첨가하였다. 이상의 추출에 의해 얻어진 액을 0.45㎛의 여과지에 통과시킨 후 유기 성분을 감압 증류시켜 최종 혼합 추출물 23 Kg을 얻었다. 500 g of mung bean, Schisandra chinensis, astronomical dong, thorny cucumber, antler, yellow, and yulpi were prepared, and then chopped and powdered, and 5 times the amount of alcohol was added and extracted at a temperature of 80 ° C. for 5 hours. Similarly, 500 g of Peony, Sukji-hwang, Baekbong-ryeong, Ganoderma lucidum, Licorice, Ginkgo biloba, Angelica, Yulmu, and Sangbaekpi were prepared, and then sliced and powdered, 5 times of water was added, and extracted at a temperature of 80 ° C. for 5 hours. 500 g of cucumbers were juiced and then the extracts were combined. After the extraction, the remaining residue was added again 5 times with ethanol (95%) and extracted again in the same manner, and extracted again with 50% concentration of ethanol in the remaining extraction foil (抽出 粕). Each extract was combined by extracting all components dissolved in water and an organic solvent by extracting components dissolved only in water by tertiary extraction with only 5 times of water with respect to the residual extract. The extraction temperature was maintained at 30 to 100 ° C., the extraction time was 1 hour to 1 week, and in some cases at room temperature for about 6 months. The solvent content was generally added in 5 times volume ratio. The liquid obtained by the above extraction was passed through 0.45 micrometer filter paper, and the organic component was distilled under reduced pressure and 23 Kg of final mixed extracts were obtained.
실시예 2에서 얻은 광물질 용해액과 본 실시예에 의해 얻어진 혼합 추출액을 중량을 기준으로 2:8의 비율로 혼합하여, 필요에 따라 희석하여 이후의 시험예에서 사용하였다. The mineral solution obtained in Example 2 and the mixed extract obtained in this example were mixed at a ratio of 2: 8 by weight, diluted as necessary, and used in the following test example.
실시예 4: 마스크 팩의 제조Example 4: Preparation of Mask Packs
물 100ml에 상기 실시예 3에서 제조된 기능성 한방 화장료 추출액 10ml, 글리세린 1g, 에탄올(95%) 2ml을 첨가한 다음 이를 부직포 100g에 1시간 동안 침지시켜 식물 추출물을 포함하는 마스크 팩을 제조하였다.To 100 ml of water, 10 ml of the functional herbal cosmetic extract prepared in Example 3, 1 g of glycerin, and 2 ml of ethanol (95%) were added and then immersed in 100 g of nonwoven fabric for 1 hour to prepare a mask pack including the plant extract.
실시예 5: 유아용 물티슈의 제조Example 5 Preparation of Infant Wipes
물 100ml에 상기 실시예 3에서 제조된 한방 화장료 추출물 10ml, 글리세린 1g, 에탄올(95%) 2ml을 첨가하여 이를 순면 100g에 3시간 동안 침지시켜 식물 추출물을 포함하는 유아용 물티슈를 제조하였다.10ml of herbal cosmetic extract prepared in Example 3, 1 g of glycerin, 2 ml of ethanol (95%) were added to 100 ml of water, and the result was immersed in 100 g of cotton for 3 hours to prepare a wet wipe including plant extract.
실시예 6: 마사지 크림의 제조Example 6: Preparation of Massage Cream
실시예 2에서 제조된 액상의 광물 용해액 10ml, 실시예 3에서 제조된 식물 추출물 10ml, 글리세린 4g, 트리에탄올아민 2g, 토코페릴아세테이트 0.4g, 유동파라핀 30g 및 정제수를 첨가하여 광물 용해액을 포함하는 마사지 크림을 제조하였다.10 ml of liquid mineral solution prepared in Example 2, 10 ml of plant extract prepared in Example 3, glycerin 4 g, triethanolamine 2 g, tocopheryl acetate 0.4 g, liquid paraffin 30 g and purified water to add a mineral solution Massage creams were prepared.
시험예 1: 급성 독성 시험Test Example 1: Acute Toxicity Test
실시예 2에 따른 안정화 광물 용해액의 실험동물에 대한 독성 실험을 수행하고 그 독성유무를 관찰하였다. 실험용동물은 4, 5주령의 체중 105ㅁ4g의 수컷과 95ㅁ3g의 암컷의 SPF SD계 래트(구입처: 소망축산) 60마리를 사용하였고 본 발명의 광물 용해액과 음성대조군으로서 증류수를 사용하여 시험하였다. 먼저, 상기 래트들을 온도 22±2 ℃, 상대습도 53±2% 및 형광등 조명(09:00 점등-18:00 소등)의 명암사이클, 150-300 Lux의 조도 조건을 갖춘 실험실 사육 상자에서 약 1주일 정도의 기간에 걸쳐 순화시킨 다음, 건강한 동물들만을 선택하여 평균 체중이 일치하도록 각 군으로 나누고 일일 1회 20ml/kg의 양으로 14일 동안 강제 경구투여한 다음, 일반상태의 변화, 중독증상, 운동성, 외관, 자율신경, 체중변화 및 사망동물의 유무에 관하여 점검하였다.Toxicity experiments were performed on experimental animals of the stabilized mineral solution according to Example 2, and their presence was observed. Experimental animals were used for 60 SPF SD rats (purchased from: hoped livestock) of 105 and 4 g males and 95 and 3 g females weighing 4 and 5 weeks of age. Distilled water was used as the mineral solution and negative control group of the present invention. Tested. First, the rats were placed in a laboratory breeding box equipped with a temperature cycle of 22 ± 2 ° C., a relative humidity of 53 ± 2%, a light intensity cycle of fluorescent lighting (09:00 lit-18: 00 light off), and illumination conditions of 150-300 Lux. After a week-long period of acclimatization, select only healthy animals, divide them into groups to match their average weight, and forcibly orally for 14 days at a daily dose of 20ml / kg. , Motility, appearance, autonomic nerves, weight change and the presence of dead animals were checked.
실험 결과에 의하면, 실험기간 동안 체중에 있어서 5% 이내의 변화를 보였으나 유의성은 없었고, 시료의 양을 액상으로 시험동물에 투여가능한 최대량인 kg당 20ml의 최고 농도를 선정하였음에도 사망동물이 관찰되지 않아 개략의 치사량 산출은 불가하였으므로 LD50은 20ml/kg B.W.이상인 것으로 나타났고, 특이한 일반증상이나 부검시 특이한 병변이 관찰되지 않았으므로 이를 종합적으로 판단해보면 상기 조성물은 독성이 없는 것으로 판명되었다.
According to the experimental results, there was no significant change in the body weight within 5% of the experimental period, but there was no significance. No dead animals were observed even though the maximum concentration of 20ml / kg was selected, which is the maximum amount that can be administered to the test animals in liquid form. Therefore, the approximate fatality calculation was not possible, so LD 50 was found to be 20 ml / kg BW or more, and no unusual lesions were observed at the time of autopsy or general autopsy, and the composition was found to be non-toxic.
시험예 2: 피부자극시험Test Example 2: Skin irritation test
본 발명의 실시예 4에 따른 마스크 팩에 사용된 조성물의 실험 동물에 대한 자극성 정도를 알아보고자 피부자극 실험을 수행하였다. 실험동물로는 체중 2.5-2.8 kg의 3-4개월령의 뉴질랜드 white rabbit(공급원: 소망축산) 6 마리를 사용하였다. 먼저, 실험 동물들을 입수후 1주일간 동물실에서 순화시키고 순화기간중 일 반 상태를 관찰하여 건강한 동물만을 시험에 사용하였다. 토끼는 시험물질 적용 24시간 전에 제모를 실시하여 처치 구획 및 대조 구획으로 구분한 다음 시험동물 한 마리당 시험물질 0.5 ml씩 투여부위에 1회 도포하고, 무처치 대조구획에는 멸균 생리 식염수를 동량 도포하였다. 부착 후 고형 재질의 박지로 덮고 테이프를 사용하여 고정한 후 일정시간 적용시켰다. 적용시간 종료후에는 생리식염수를 이용해 도포부를 가볍게 세정해 주었다. 시험물질 투여후 일주일간 매일 외관, 사료 및 음수 소비 상태와 임상증상 등에 대하여 관찰하고, 적용후 7일째에 국소마취제(리도카인, 광명약품)를 귀정맥을 통해 주입하여 안락사시킨 후 부검하여 이상유무를 육안으로 관찰하였다.Skin irritation experiments were performed to determine the degree of irritation of experimental animals of the composition used in the mask pack according to Example 4 of the present invention. Six experimental white New Zealand white rabbits (source: wished livestock) weighing 2.5-2.8 kg were used as experimental animals. First, the experimental animals were purified in the animal room for 1 week after the acquisition and observed the general state during the acclimation period, and only healthy animals were used for the test. Rabbits were depilated 24 hours before application of the test substance, divided into treatment and control compartments, and then applied 0.5 ml of test substance per test animal to the administration site once, and the same treatment was applied with sterile physiological saline in the untreated control compartment. . After attaching, it was covered with a solid foil and fixed with a tape and then applied for a certain time. After the end of the application time, the application part was lightly washed with saline solution. Observe the appearance, feed and drinking consumption and clinical symptoms every day for one week after the administration of the test substance, and after 7 days of application, local anesthetics (lidocaine, photomedicine) were injected through the ear vein and euthanized, followed by necropsy. Observed visually.
피부반응의 평가는 "의약품 등의 독성시험기준"을 이용하여 24 시간과 72 시간에 대하여 판정하였다. 또한 피부에 대한 자극성의 정도 판정은 일반적으로 많이 이용되는 Draize의 P.I.I.(Primary Irritation Index)의 산출방법에 따랐다. 시험결과 시험물질 도포부위의 홍반과 가피형성 및 부종 등의 자극성은 인정되지 않았으며, Draize의 P.I.I에 의한 피부1차 자극율은 "0"으로 평가되었다.
Evaluation of skin reactions was carried out for 24 hours and 72 hours using the "toxicity test criteria, such as pharmaceuticals". In addition, the determination of the degree of irritation to the skin was based on the commonly used method of calculating the primary irritation index (PII) of Draize. As a result, irritation such as erythema, skin formation and edema of the test substance application site was not recognized. The primary irritation rate of Draize's PII was evaluated as "0".
시험예 3: 일회용 마스크팩의 임상시험 Test Example 3: Clinical Trial of Disposable Mask Pack
상기 실시예 4에서 제조된 마스크 팩의 임상 효능(미백효과, 보습효과)을 시험하기 위하여 20대∼40대의 여성 자원자 50명을 대상으로 다음 표 3에 나타낸 2가지 항목에 대하여 검사 방식을 설명하고 익숙할 수 있도록 연습시킨 다음 임상 검사를 수행하였다. 구체적으로 본 발명의 제품을 1일 1회씩 12주 동안 사용하게 하 였다. 이후, 사용자의 반응을 피부색의 변화를 크로마메타(Minolta CR300)를 이용하여 색의 밝기 변화를 측정하고, 피부보습효과는 코네오메터를 가지고 측정하여 그 결과를 하기 표 3에 나타내었다. 평가 기준은 4 단계로 나누고 점수가 높을수록 좋은 결과를 나타내는 것으로 정하였다. 즉, 1: 차이가 없음, 2: 다소 개선됨, 3: 상당히 개선됨, 4: 현저히 개선됨. 제시된 값은 평균치이다. In order to test the clinical efficacy (whitening effect, moisturizing effect) of the mask pack manufactured in Example 4, the test method will be described with respect to two items shown in the following Table 3 for 50 female volunteers in their 20s to 40s. Exercises were made to familiarize themselves, followed by clinical examination. Specifically, the product of the present invention was used once a day for 12 weeks. Then, the user's response to the change in skin color using chromatome (Minolta CR300) to measure the change in brightness of the color, the skin moisturizing effect is measured with a coneometer and the results are shown in Table 3 below. The evaluation criteria were divided into four stages, and the higher the score was, the better the result was. That is, 1: no difference, 2: somewhat improved, 3: significantly improved, 4: significantly improved. The values presented are averages.
위의 결과로부터 알 수 있는 바와 같이, 본 발명의 기능성 화장료 조성물은 피부를 부드럽게 하는 등 신진 대사를 활성화시키고, 현저한 보습효과, 미백효과를 나타냄을 알 수 있다.
As can be seen from the above results, it can be seen that the functional cosmetic composition of the present invention activates metabolism, such as softening the skin, and exhibits significant moisturizing and whitening effects.
본 발명에 따른 천연 화장료 조성물은 화학 합성제가 아닌 천연 물질의 추출물을 포함하고 있으므로, 피부에 대한 자극성이나 독성이 없어서 안정성이 우수하며, 원적외선 방사 및 음이온 발생 등의 효능으로 인하여 인체에 이로울 뿐만 아니라 피부미백 효과 및 보습 효과가 있어서 피부촉감 개선 및 지방성분을 제거하는 등의 여러 가지 유익한 기능을 제공하므로 이러한 기능성을 요하는 화장용 제품에 사용될 수 있다.
Since the natural cosmetic composition according to the present invention contains an extract of a natural substance other than a chemical synthetic agent, there is no irritation or toxicity to the skin and thus the stability is excellent, and it is not only beneficial to the human body due to the effects of far infrared radiation and anion generation. The skin whitening and moisturizing effects provide various beneficial functions such as improving skin feel and removing fat components, and thus can be used in cosmetic products requiring such functionality.
Claims (5)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020050000751A KR20060080376A (en) | 2005-01-05 | 2005-01-05 | Cosmetic composition containing inorganic mineral solution and plant extract and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020050000751A KR20060080376A (en) | 2005-01-05 | 2005-01-05 | Cosmetic composition containing inorganic mineral solution and plant extract and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20060080376A true KR20060080376A (en) | 2006-07-10 |
Family
ID=37171735
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020050000751A KR20060080376A (en) | 2005-01-05 | 2005-01-05 | Cosmetic composition containing inorganic mineral solution and plant extract and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
KR (1) | KR20060080376A (en) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100855069B1 (en) * | 2007-01-25 | 2008-08-29 | (주)동양리빙퀘스트 | Manufacturing method of atopic eczema relaxant composition using natural materials |
KR100858104B1 (en) * | 2007-04-20 | 2008-09-10 | 백기영 | How to extract the medicinal components of medicinal herbs using silicate |
KR100890070B1 (en) * | 2007-01-25 | 2009-03-27 | (주)동양정밀 | Atopy eczema relaxant composition using natural material |
US20110189318A1 (en) * | 2010-01-29 | 2011-08-04 | Misato Sugahara | Methods for enhancing the expression of intracellular redox-associated factors |
KR101463841B1 (en) * | 2008-05-30 | 2014-11-21 | (주)아모레퍼시픽 | Cosmetic composition containing fermented extracts with salt |
KR20150008609A (en) * | 2013-07-15 | 2015-01-23 | 주식회사 떠오름 | Cosmetic composition comprising natural minerals |
KR102211250B1 (en) * | 2020-01-28 | 2021-02-03 | (주)로우카본 | Method for preparing desulfurization agent for sulfur oxide reduction of high sulfur fuel oil (HSFO) and desulfurization agent using the same |
KR20210151587A (en) | 2020-06-05 | 2021-12-14 | 주식회사 셀레너스 | Method for manufacturing a cosmetic composition comprising an illite extract as an active ingredient |
KR20220112988A (en) * | 2021-02-05 | 2022-08-12 | 경상국립대학교산학협력단 | A cosmetic composition for skin whitening containing loess extract |
EP4134064A1 (en) | 2021-08-13 | 2023-02-15 | Macsumsuk GM Co., Ltd. | Method for preparing cosmetic product using dead sea mud and macsumsuk |
KR20230137526A (en) * | 2022-03-21 | 2023-10-05 | 미온바이오 주식회사 | ION PlASTER MANUFACTURING METHOD FOR HUMAN AND PET, COMPOSITION THEREOF, AND ITS PRODUCT |
-
2005
- 2005-01-05 KR KR1020050000751A patent/KR20060080376A/en not_active Application Discontinuation
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100855069B1 (en) * | 2007-01-25 | 2008-08-29 | (주)동양리빙퀘스트 | Manufacturing method of atopic eczema relaxant composition using natural materials |
KR100890070B1 (en) * | 2007-01-25 | 2009-03-27 | (주)동양정밀 | Atopy eczema relaxant composition using natural material |
KR100858104B1 (en) * | 2007-04-20 | 2008-09-10 | 백기영 | How to extract the medicinal components of medicinal herbs using silicate |
KR101463841B1 (en) * | 2008-05-30 | 2014-11-21 | (주)아모레퍼시픽 | Cosmetic composition containing fermented extracts with salt |
US20110189318A1 (en) * | 2010-01-29 | 2011-08-04 | Misato Sugahara | Methods for enhancing the expression of intracellular redox-associated factors |
KR20150008609A (en) * | 2013-07-15 | 2015-01-23 | 주식회사 떠오름 | Cosmetic composition comprising natural minerals |
KR102211250B1 (en) * | 2020-01-28 | 2021-02-03 | (주)로우카본 | Method for preparing desulfurization agent for sulfur oxide reduction of high sulfur fuel oil (HSFO) and desulfurization agent using the same |
KR20210151587A (en) | 2020-06-05 | 2021-12-14 | 주식회사 셀레너스 | Method for manufacturing a cosmetic composition comprising an illite extract as an active ingredient |
KR20220112988A (en) * | 2021-02-05 | 2022-08-12 | 경상국립대학교산학협력단 | A cosmetic composition for skin whitening containing loess extract |
EP4134064A1 (en) | 2021-08-13 | 2023-02-15 | Macsumsuk GM Co., Ltd. | Method for preparing cosmetic product using dead sea mud and macsumsuk |
KR20230025159A (en) | 2021-08-13 | 2023-02-21 | 맥섬석 지.엠. 주식회사 | manufacturing method of cosmetic compoaition using Dead sea mud and Maeksumseok |
KR20230137526A (en) * | 2022-03-21 | 2023-10-05 | 미온바이오 주식회사 | ION PlASTER MANUFACTURING METHOD FOR HUMAN AND PET, COMPOSITION THEREOF, AND ITS PRODUCT |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR101805004B1 (en) | Fermentation method using medicinal leaf and skin external composition containing fermented extract by the method | |
KR101868050B1 (en) | Fermentation method using medicinal flower and skin external composition containing fermented extract by the method | |
KR102288724B1 (en) | Multi functional shampoo for pet comprising functional complex composition for improving function of anti-bacterial, sterilization, anti-inflammation and skin soothing, and enhancing skin immune and manufacturing method thereof | |
CN102805723A (en) | Skin-protecting and acne-removing Chinese medicinal facial mask powder | |
CN104434618B (en) | Have whitening, nti-freckle concurrently and print nine grass green frosts of effect and preparation method thereof | |
KR102273358B1 (en) | Sanitary absorption pad comprising multi-functional sheet for improving function of anti-bacterial, sterilization and deodorize and irradiating far-infrared rays and negative ions and manufacturing method thereof | |
KR102320299B1 (en) | Functional soap composition containing natural ingredients | |
CN106035861A (en) | Inonotus obliquus substitutional tea with health-care functions and preparation method thereof | |
CN102845571A (en) | Mulberry leaf tea for spot removing and face nourishing, and its preparation method | |
KR100873033B1 (en) | Cosmetic composition for massage pack | |
KR20060080376A (en) | Cosmetic composition containing inorganic mineral solution and plant extract and preparation method thereof | |
KR101089879B1 (en) | Sunscreen tape | |
KR101065799B1 (en) | Manufacturing method of bath salt using sun salt | |
KR101334827B1 (en) | Method making beauty art pack of the principal ingredient an stuff of a Melon seed oil | |
CN109364184A (en) | A kind of health memory pillow improving sleep | |
CN103948541B (en) | A kind of preparation method of black currant hair color shampoo | |
KR101606381B1 (en) | Manufacture method of complex beauty Salt using solar salt processing environmentally friendly | |
KR100825436B1 (en) | Skin improvement cosmetic soap composition | |
KR20210142545A (en) | Manufacturing method of homemade snack of fishery products keeping its original form for companion animal and homemade snack of fishery products keeping its original form for companion animal manufactured using the method | |
KR101223683B1 (en) | Cosmetic composition for whitening skin containing the Dong-A extracts and the manufacturing method therof and the Cosmetic products using the same | |
KR101186508B1 (en) | Manufacturing method of healthy food using germinated grain | |
KR20140137155A (en) | Manufacturing methods of fermentation black Korean medicine with far-infrared water | |
CN107412345A (en) | A kind of passion fruit seed oil lozenge and preparation method thereof | |
CN104473250A (en) | Yam beverage and preparation method thereof | |
CN103920002A (en) | Hair growth agent and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 20050105 |
|
PG1501 | Laying open of application | ||
A201 | Request for examination | ||
PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20071113 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 20050105 Comment text: Patent Application |
|
E902 | Notification of reason for refusal | ||
PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20090513 Patent event code: PE09021S01D |
|
E601 | Decision to refuse application | ||
PE0601 | Decision on rejection of patent |
Patent event date: 20090814 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20090513 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |