KR20060022610A - Herbal Medicine Composition for Cancer Treatment - Google Patents
Herbal Medicine Composition for Cancer Treatment Download PDFInfo
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- KR20060022610A KR20060022610A KR1020040071482A KR20040071482A KR20060022610A KR 20060022610 A KR20060022610 A KR 20060022610A KR 1020040071482 A KR1020040071482 A KR 1020040071482A KR 20040071482 A KR20040071482 A KR 20040071482A KR 20060022610 A KR20060022610 A KR 20060022610A
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- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 18
- 201000011510 cancer Diseases 0.000 title claims abstract description 16
- 238000011282 treatment Methods 0.000 title claims abstract description 12
- 239000000203 mixture Substances 0.000 title claims abstract description 6
- 241000411851 herbal medicine Species 0.000 title claims abstract description 4
- 235000002789 Panax ginseng Nutrition 0.000 claims abstract description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000003814 drug Substances 0.000 abstract description 16
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 8
- 229940079593 drug Drugs 0.000 abstract description 8
- 201000010099 disease Diseases 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 7
- 241000208340 Araliaceae Species 0.000 abstract description 6
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 abstract description 6
- 235000003140 Panax quinquefolius Nutrition 0.000 abstract description 6
- 235000008434 ginseng Nutrition 0.000 abstract description 6
- 241000282414 Homo sapiens Species 0.000 abstract description 5
- 208000004998 Abdominal Pain Diseases 0.000 abstract description 4
- JLUQTCXCAFSSLD-NXEZZACHSA-N Anemonin Chemical compound C1=CC(=O)O[C@]11[C@@]2(C=CC(=O)O2)CC1 JLUQTCXCAFSSLD-NXEZZACHSA-N 0.000 abstract description 3
- JLUQTCXCAFSSLD-UHFFFAOYSA-N Anemonin Natural products C1=CC(=O)OC11C2(C=CC(=O)O2)CC1 JLUQTCXCAFSSLD-UHFFFAOYSA-N 0.000 abstract description 3
- 206010054787 Haemorrhoidal haemorrhage Diseases 0.000 abstract description 2
- 208000005374 Poisoning Diseases 0.000 abstract description 2
- 230000000202 analgesic effect Effects 0.000 abstract description 2
- 230000003110 anti-inflammatory effect Effects 0.000 abstract description 2
- 230000000259 anti-tumor effect Effects 0.000 abstract description 2
- 210000003169 central nervous system Anatomy 0.000 abstract description 2
- 210000000750 endocrine system Anatomy 0.000 abstract description 2
- 208000001780 epistaxis Diseases 0.000 abstract description 2
- 230000002964 excitative effect Effects 0.000 abstract description 2
- 238000010438 heat treatment Methods 0.000 abstract description 2
- 210000000936 intestine Anatomy 0.000 abstract description 2
- 210000004185 liver Anatomy 0.000 abstract description 2
- 208000011309 nasal bleeding Diseases 0.000 abstract description 2
- 230000000144 pharmacologic effect Effects 0.000 abstract description 2
- 231100000572 poisoning Toxicity 0.000 abstract description 2
- 230000000607 poisoning effect Effects 0.000 abstract description 2
- 230000001850 reproductive effect Effects 0.000 abstract description 2
- 239000000932 sedative agent Substances 0.000 abstract description 2
- 230000001624 sedative effect Effects 0.000 abstract description 2
- 208000004371 toothache Diseases 0.000 abstract description 2
- 208000024891 symptom Diseases 0.000 abstract 2
- 230000002195 synergetic effect Effects 0.000 abstract 2
- 208000011671 Lacrimal disease Diseases 0.000 abstract 1
- 241000442474 Pulsatilla vulgaris Species 0.000 abstract 1
- 230000007123 defense Effects 0.000 abstract 1
- 230000003028 elevating effect Effects 0.000 abstract 1
- 229940107131 ginseng root Drugs 0.000 abstract 1
- 231100000957 no side effect Toxicity 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000001502 supplementing effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 3
- 241000357622 Codonopsis javanica Species 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000002512 chemotherapy Methods 0.000 description 2
- 238000001959 radiotherapy Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 241000648772 Anemone patens subsp. multifida Species 0.000 description 1
- 241001628605 Anemone tomentosa Species 0.000 description 1
- 206010020843 Hyperthermia Diseases 0.000 description 1
- 241000218201 Ranunculaceae Species 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000007016 complementary pharmacologic effect Effects 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 238000007602 hot air drying Methods 0.000 description 1
- 230000036031 hyperthermia Effects 0.000 description 1
- 238000009169 immunotherapy Methods 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
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- 239000002994 raw material Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 229940126585 therapeutic drug Drugs 0.000 description 1
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
본 발명은 백두옹(白頭瓮 할미꽃뿌리)과 홍삼을 원료로 한 암(癌) 치료용 생약 조성물에 관한 것으로서, 물 1.5∼2.5ℓ에 백두옹 25∼30g, 홍삼55∼60 g, 즉 백두옹과 홍삼(紅蔘)이 1 : 2의 비율이 되도록 넣고 약한 불에서 30분∼1시간 동안 가열하여 물의 부피가 처음 부피의 반이 될 정도로 달여서 추출된 한약재 약액이다.The present invention relates to a herbal composition for the treatment of cancer based on baekduong (頭 瓮) red ginseng root and red ginseng, 25 to 30g of baekduong, 55 to 60g of red ginseng, namely baekduong and red ginseng 되도록) is the ratio of 1: 2 and is a herbal medicine extracted by heating for 30 minutes to 1 hour on low heat to the extent that the volume of water is half of the initial volume.
이 약액은 약재들이 지닌 약리 작용을 상호 상승 및 보완시켜 암 환자를 치료할 수 있는 효과가 있고, 인체에 부작용이 전혀 없어 노약자, 허약자, 유 ·소아에게 적용할 수 있을 뿐만 아니라 암 증상 및 그 관련 예방효과가 탁월하여 환자의 증상에 따라 약간의 차이는 있을 지라도 1일 2∼3회씩 복용함으로써 완치가 가능한 효과를 얻을 수 있다.This medicine is effective to treat cancer patients by mutually elevating and supplementing the pharmacological action of the medicines, and has no side effects on the human body, so it can be applied to the elderly, the weak, infants and children, as well as the prevention of cancer symptoms and related diseases. The effect is so excellent that a slight difference depending on the patient's symptoms can be obtained by taking 2-3 times a day can be cured.
백두옹은 한방에서 장의 열을 식히고, 열독(熱毒), 그밖에 복통, 치통 등 진통작용이 있는 약물로서 열성하리(熱性下痢), 복통, 비혈(鼻血), 치질출혈 등의 치료에 응용되어 왔으며, 백두옹에 함유된 아네모닌이란 성분은 적은 양에서는 심장(心臟) 박동의 진폭을 축소시키고, 많은 양에서는 심장을 정지시키는 작용이 밝혀졌으며 오키나린은 심장을 튼튼하게 하는 작용이 있음이 밝혀졌다.Baekduong cools the heat of the intestines in one shot, and has been applied to the treatment of febrile slack, abdominal pain, nasal bleeding, hemorrhoidal bleeding as a drug with analgesic action such as heat poisoning, abdominal pain and toothache. Anemonin, contained in baekduong, has been shown to reduce the amplitude of the heartbeat in small amounts, to stop the heart in large amounts, and to make the heart stronger.
홍삼은 과학적으로 중추신경에 대해서 진정작용과 흥분작용이 있으며, 간을 보호하고 내분비계에 작용하여 생식효과에 간접적으로 유효하게 작용하며, 특히 항염(抗炎) 및 항종양작용(抗腫瘍作用)에 효능이 있는 것으로 알려지고 있다.Red ginseng has scientifically sedative and excitatory effects on the central nervous system, protects the liver and acts indirectly on the reproductive effects by acting on the endocrine system. Especially, anti-inflammatory and anti-tumor effects It is known to be effective in.
홍삼의 효과 중 중요한 것은 어댑토겐(adaptogen: 滴應素) 효과로서 주위 환경으로부터 오는 각종 유해작용인 누병(淚病), 각종 스트레스 등에 대해 방어능력을 증가시켜 생체가 보다 쉽게 적응하도록 하는 능력이 있음이 과학적으로 입증되고 있다.The most important of the effects of red ginseng is the adaptogen effect, which increases the ability of the living body to adapt more easily by increasing the defense ability against various diseases such as lacrimal disease and various stresses from the environment. This is scientifically proven.
종래 한의학에서도 암 치료에 인삼이 널리 사용되어 왔으며 특히 홍삼은 그 약효가 인체에 치명적일 정도로 강력한 백두옹과 결합, 상승 작용하여 암세포의 근(根)을 파괴할 수 있는 약효를 발휘하는 것으로 사료되며 이에 완치의 효과를 얻을 수 있다.In traditional Chinese medicine, ginseng has been widely used for the treatment of cancer. Especially, red ginseng is combined with synergistic strong baekduong and its synergistic effect, which can destroy the roots of cancer cells. The effect can be obtained.
백두옹, 할미꽃뿌리, 홍삼, 아네모닌, 오키나린Baekduong, Pasqueflower, Red Ginseng, Anemonin, Okinarin
Description
본 발명은 백두옹과 홍삼을 원료로 하여 일반적으로 치료가 거의 불가능하다고 여겨져 온 많은 종류의 암 질환을 획기적으로 치료할 수 있는 암 치료용 생약 조성물에 관한 것이다.The present invention relates to a herbal composition for cancer treatment that can cure a great number of cancer diseases that are generally considered to be almost impossible to treat based on baekduong and red ginseng.
암의 치료는 서양 의학에서 수술 ·방사선요법 ·항암화학요법 등의 3대 치료법이 널리 사용되며 병용되는데, 수술 및 방사선요법은 주로 국소 치료방법이며, 항암화학요법은 전신 치료 방법이다. 이 밖에도 몇 가지 종양에 따라서는 면역요법·고열요법 및 영양요법 등이 행해지고 있다.The treatment of cancer is widely used in Western medicine, such as surgery, radiation therapy, chemotherapy and the like, widely used, surgery and radiation therapy is mainly a topical treatment method, chemotherapy is a systemic treatment method. In addition to some tumors, immunotherapy, hyperthermia and nutrition therapy are performed.
한의학에서 암의 형성은 주로 인체의 정기가 부족한 상태에서 과도한 정신적 자극(즉, 喜 ·怒 ·憂 ·思 ·悲 ·恐 ·驚 등의 七情의 과도)이 있거나, 외사(外邪)가 정체하여 기체혈어(氣滯血瘀)하고 담음독취(痰飮獨聚)하므로 서로 엉겨서 맺히고 얽혀서 마침내 종괴가 형성되는 것으로 보고 있다.In Chinese medicine, the formation of cancer is mainly due to excessive mental stimulation (ie, excessive excessive emotions such as 喜 · 怒 · 憂 · 思 · 悲 · 恐 · 驚) in the state of lack of regularity of the human body, As a result of gaseous blood (氣滯血瘀) and haeumdok poisonous (하므로) tangled together and entangled with each other is finally seen to form a mass.
이에 대한 치법은 초기에는 질병을 직접 공격하는 공법(攻法)을 위주로 하고, 중기에는 공법과 보법을 겸하여 시행하고, 말기에는 부정(扶正 정기를 돕는 것)하는 법을 위주로 치료하는 것이 일반적인 규율이나, 최근에는 대개 공법과 보 법을 겸하여 치료하는 경향이 있다.In general, the rule is to treat the disease directly at the beginning, and to treat the disease at the end of the day. In recent years, there is a general tendency to treat both a combination of techniques and protection.
치료약물에는 당삼(黨蔘) ·백출(白朮), 복령(茯笭)·황기(黃
본원은 인체에 다양한 원인과 다양한 형태로 발병하여 현재 인류에게 가장 고통스런 질병으로 다루어지고 있는 암을 치유해 내기 위하여, 기존의 한의학 치료법을 응용하고 민간에서 내려오는 치료법들을 오랫동안 연구하고 시술하여 암 치료에 탁월한 효과를 얻은 경험을 바탕으로 하여, 백두옹과 홍삼을 이용한 획기적인 암 치료용 생약조성물을 제공하는데 그 목적이 있다.To treat cancers that are caused by various causes and forms in the human body and treat them as the most painful diseases to human beings, we apply existing Korean medicine therapies and research and practice the treatments that come down from the private sector for a long time. Based on the experience gained, the purpose is to provide a herbal composition for the treatment of cancer using baekduong and red ginseng.
상기한 바와 같이 본 발명은, 물 1.5∼2.5ℓ에 백두옹 25∼30g, 홍삼55∼60 g, 즉 백두옹과 홍삼(紅蔘)이 1 : 2의 비율이 되도록 넣고 약한 불에서 30분∼1시간 동안 가열하여 물의 부피가 처음 부피의 반이 될 정도로 달인 한약재 약액을 추출하여 이루어진다.As described above, in the present invention, 1.5 to 2.5 liters of water contains 25 to 30 g of baekduong and 55 to 60 grams of red ginseng, that is, baekduong and red ginseng at a ratio of 1: 2. It is made by extracting decoction of Chinese herbal medicine so that the volume of water is half of the initial volume by heating.
본 발명에 사용하는 백두옹은 정식(定式)으로는 할미꽃뿌리가 사용되지만 이것 이외에도 백두옹이라고 부르는 한약은 10수종(數種)이 있으며, 그 중에서 중요 한 것은 미나리아재비과(Ranunculaceae)의 Anemone tomentosa(甘肅蘭州) 등의 뿌리 및 전초를 백두옹(白頭翁)이라고 하며, 봄철에 나는 할미꽃의 뿌리를 햇볕에 말려 약용으로 사용한다.Baekduong used in the present invention is used as a regular paleum flower root, but in addition to this, there are 10 species of Chinese medicine called Baekduong, the most important of which is Anemone tomentosa (Ranunculaceae) The roots and outposts of the) are called Baekduong (白 봄), and in the spring, the roots of pasqueflowers are dried in the sun and used for medicinal purposes.
백두옹은 한방에서 장의 열을 식히고, 열독(熱毒), 그밖에 복통, 치통 등 진통작용이 있는 약물로서 열성하리(熱性下痢), 복통, 비혈(鼻血), 치질출혈 등의 치료에 응용되어 왔으며, 백두옹에 함유된 아네모닌이란 성분은 적은 양에서는 심장(心臟) 박동의 진폭을 축소시키고, 많은 양에서는 심장을 정지시키는 작용이 밝혀졌으며 오키나린은 심장을 튼튼하게 하는 작용이 있음이 밝혀졌다.Baekduong cools the heat of the intestines in one shot, and has been applied to the treatment of febrile slack, abdominal pain, nasal bleeding, hemorrhoidal bleeding as a drug with analgesic action such as heat poisoning, abdominal pain and toothache. Anemonin, contained in baekduong, has been shown to reduce the amplitude of the heartbeat in small amounts, to stop the heart in large amounts, and to make the heart stronger.
홍삼은 4년생 이상의 수삼을 물로 깨끗하게 씻고, 일정한 용기에 넣어 가열된 수증기를 이용하여, 크기에 따라 일정시간 찐다(蒸蔘). 증삼된 것은 1차 열풍건조 후부터는 태양열을 이용하거나 기타 방법으로 수분이 12.5∼13.5％ 정도 될 때까지 건조하며 잔뿌리(홍미삼)를 따내고 모양을 가다듬어(胴體), 등급별로 선별된다.Red ginseng is washed with fresh ginseng 4 years or older with water, and steamed for a certain time depending on the size by using heated steam in a certain container. Thickened ginseng is dried by solar heat or other method until 12.5 ~ 13.5% of moisture after primary hot air drying. The fine roots are picked and the shape is refined.
홍삼은 과학적으로 중추신경에 대해서 진정작용과 흥분작용이 있으며, 간을 보호하고 내분비계에 작용하여 생식효과에 간접적으로 유효하게 작용하며, 특히 항염(抗炎) 및 항종양작용(抗腫瘍作用)에 효능이 있는 것으로 알려지고 있다.Red ginseng has scientifically sedative and excitatory effects on the central nervous system, protects the liver and acts indirectly on the reproductive effects by acting on the endocrine system. Especially, anti-inflammatory and anti-tumor effects It is known to be effective in.
홍삼의 효과 중 중요한 것은 어댑토겐(adaptogen: 適應素) 효과로서 주위 환경으로부터 오는 각종 유해작용인 누병(淚病), 각종 스트레스 등에 대해 방어능력을 증가시켜 생체가 보다 쉽게 적응하도록 하는 능력이 있음이 과학적으로 입증되고 있다.The most important of the effects of red ginseng is the adaptogen effect, which increases the ability of the organism to adapt more easily by increasing the defensive ability against the disease, stress, and other harmful effects from the environment. Scientifically proven.
상기 약재 원료들의 혼합양은 환자의 체질과 질환의 경중에 따라 다소 증감할 수 있겠으나 약재들 간의 상호 보완적인 약리효과 등을 고려하여 상술된 바와 같이 백두옹과 홍삼이 1 : 2의 비율이 되도록 하는 것이 가장 적합하다.The mixed amount of the raw materials of the medicine may increase or decrease depending on the severity of the patient and the severity of the disease, but as described above in consideration of the complementary pharmacological effects between the medicines such that Baekduong and red ginseng is 1: 1: Most suitable.
이와같이 혼합된 약재들을 물 1.5∼2.5ℓ에 넣고, 약한 불에서 약30분∼1시간 동안 가열하여 물의 부피가 처음 부피의 반이 될 정도로 달여서 추출함으로써 약액을 완성한다.The mixed medicines are added to 1.5-2.5 L of water, heated at low heat for about 30 minutes to 1 hour, and then extracted to the extent that the volume of water is half of the initial volume to complete the chemical solution.
상기 약액은 액기스 상태가 되도록 더 오랜 시간동안 끓여서 액기스 상태의 액제나캅셀제, 시럽제, 환제 등 내복이 가능한 형태로 제형화한 조성물을 제조할 수도 있다.The chemical solution may be prepared by boiling for a longer time so as to be in an aqueous state, and formulated in an internally available form such as an aqueous solution, a capsule, a syrup, or a pill.
상술한 바와 같이 본 발명에 의한 암 치료용 생약 조성물은 백두옹과 홍삼을 본 발명에 따른 양으로 혼합하여 조제함으로써, 약제들이 지닌 약리 작용을 상호 상승및 보완시켜줄 수 있어 항암제 및 갖가지 화학약품을 쓰지 않고도 암 환자를 치료할 수 있는 효과가 있다.As described above, the herbal composition for treating cancer according to the present invention is prepared by mixing Baekduong and red ginseng in an amount according to the present invention, thereby increasing and complementing the pharmacological action of drugs without using anticancer agents and various chemicals. It is effective in treating cancer patients.
또, 종래 한의학에서도 암 치료에 인삼이 널리 사용되어 왔으며 특히 홍삼은 그 약효가 인체에 치명적일 정도로 강력한 백두옹과 결합, 상승 작용하여 암세포의 근(根)을 파괴할 수 있어, 환자의 증상에 따라 기간의 차이는 있을 지라도 1일 2∼3회 씩 복용함으로써 완치가 가능한 효과를 얻을 수 있다.In addition, ginseng has been widely used in traditional Chinese medicine to treat cancer. Especially, red ginseng can bind and synergize with baekduong, a drug whose fatality is fatal to the human body, which can destroy the roots of cancer cells. Even though there is a difference between 2 to 3 times a day by taking a possible effect can be obtained.
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