KR200448316Y1 - Isolator for Breeding a Aseptic Pig - Google Patents

Abstract

The present invention relates to a sterile pig breeding isolator. The present invention is the main body portion 30 is composed of a case 31 and the lower frame 33, the supply and exhaust portion 60 for supplying aseptic air into the body portion 30 and discharge the internal air to the outside And, the control unit 110 for controlling the supply and exhaust unit 60, the life support unit 100 to prevent the death of sterile pig even in an emergency by the uninterruptible supply unit 101 and the safety filter 103, and the main body It is configured to include a management and maintenance unit configured to manage the sterile pigs raised in the clean state. According to the present invention configured as described above, it is possible to prevent the death of sterile pig even in an emergency by the supply / exhaust part and the safety filter, and to facilitate the cleaning and management by the management and maintenance part, thereby increasing the convenience of management.

Sterile Pig, Isolator, Uninterruptible Supply, Safety Filter

Description

Isolator for Breeding a Aseptic Pig}

The present invention relates to an isolator for aseptic pig breeding, and more particularly to an isolator for breeding aseptic pigs used as experimental animals.

In recent years, research in medical disease models, drug safety tests, drug efficacy tests, in vivo metabolic processes of drugs, drug resistance and interactions between drugs, and development of other organs include the development of other organs. As a result, experimental animals are used a lot. Most of the animals used as experimental animals are rodents such as rats, mice, and guinea pigs.

An apparatus suitable for raising such an experimental animal is an isolator. The isolator is a device that separates and isolates the external and internal environments, which minimizes contact with the external environment and removes external factors that may affect the animal in advance.

Since the isolator must exclude any microorganisms or pathogens that are not desired by the experimenter, all items entering the isolator are sterilized beforehand. In addition, the contact between the animal and the human is possible only when the glove is worn, and the air introduced into the isolator is filtered by the HEFA filter.

1 shows an isolator according to the prior art. As shown, the case 10 forming the outer shape of the isolator is composed of a frame 13 and a flexible film wall 15 overlying the frame 13.

A pedestal 17 is provided below the case 10, and the pedestal 17 is provided with an air supply / exhaust unit 19 serving as an air conditioning unit of the isolator, and the air supply / exhaust unit 19 includes a blower fan, It consists of a fan drive motor, a blower duct and a supply / exhaust filter.

One surface of the case 10 is provided with a transfer unit 20 for connecting the inside and outside of the case 10. All the necessary materials for breeding sterile animals enter and exit through the transfer unit 20.

The glove 23 is attached to the front surface of the case 10. The glove 23 is a part where the tester directly contacts the animal. A plurality of racks 25, which are a kind of shelf structure, are provided in the case 10.

However, in the aseptic animal breeding isolator according to the prior art as described above has the following problems.

Existing isolator risks the loss of all experimental results due to the death of experimental animals inside.

In addition, there is a problem that the conventional isolator is not provided with a structure suitable for sterile pigs that are frequently used to replace human organs.

The present invention is to solve such a conventional problem, the object of the present invention is to provide a structure for an emergency such as a power failure.

Another object of the present invention is to provide an isolator suitable for sterile pigs.

According to a feature of the subject innovation for achieving the above object, the subject innovation is configured to maintain the interior in a sterile state; An air supply / exhaust unit provided in the main body unit and configured to introduce sterile air into the main body unit or to discharge internal air to the outside; A control unit controlling an operation of the supply / exhaust unit; A life support unit for supplying supplementary power when the supply / exhaust unit does not operate or inflowing external air in a sterile state so that the inside of the main body unit is not sealed; It is preferable to include a management holding unit configured to.

The life support unit of the present invention is a safety filter composed of an uninterruptible supply unit for supplying power to the supply and exhaust unit even in the event of a power outage, and a HEPA filter or a ULPA filter for introducing external air in a sterile state without being sealed inside the main body. It is preferable to include.

The main body of the present invention preferably includes a case provided with a glove on one side to handle aseptic pigs from the outside, and a lower frame for supporting the case and the supply and exhaust portion.

The case of the present invention preferably includes a transfer part for entering and exiting the article into and out of the case aseptically.

The transfer unit of the present invention to selectively open and close one surface of the case; Fixing member for fixing the inner door to shield the inside of the case; and preferably comprises an outer cap for providing a space for disinfecting the goods entered into the case.

It is preferable that the management holding part of the present invention includes a lower drain for selectively carrying out the sterile pig droppings accumulated inside the case of the main body to the outside, and a cleaning unit for cleaning the inside of the case by water supplied from the outside. .

In the upper part of the lower drain of the present invention, the bottom surface formed with a gap to allow the droppings of sterile pigs to fall downward, and the lower drain hopper for collecting the droppings falling to the bottom of the bottom surface to the inlet of the lower drain, and the lower It is preferable that a valve for opening and closing the drain is further provided.

The cleaning unit of the present invention preferably further includes a water supply tank for storing water supplied from the outside, and a water supply unit for supplying water from the water supply tank and supplying the water to the case.

It is preferable that a heat generating unit for supplying heat into the case of the present invention is further provided.

It is preferable that the chain is further provided inside the case of the present invention.

The air supply unit of the air supply and exhaust portion of the present invention blower for supplying air into the case; Hepa filter for purifying the air drawn into the case; and preferably a heater for heating the air drawn into the case.

Exhaust unit of the exhaust and exhaust portion of the present invention, a blower for exhausting the outside of the case; It is preferable to include a pre-filter for preliminarily purifying the air exhausted to the outside of the case; and a HEPA filter for purifying the air exhausted to the outside of the case.

Preferably, the air supply and exhaust part of the present invention includes a perforated plate for evenly supplying the air drawn by the air supply unit into the case.

The control unit of the present invention includes a ventilation number control unit for inputting and displaying the ventilation number inside the case; A temperature controller for controlling a temperature of air introduced into the case; It is preferable to include a filter operation time display unit for displaying the use time of the filter of the supply and exhaust unit; and a pressure display unit for displaying the pressure in the case.

According to the isolator for aseptic pig breeding according to the present invention, it is possible to prevent the death of sterile pig even in the emergency by the supply and exhaust part and the safety filter, and to facilitate the cleaning and management by the management and maintenance unit, thus increasing the convenience of management. There is an advantage.

Hereinafter, with reference to the accompanying drawings a preferred embodiment of the sterile pig breeding isolator according to the present invention will be described in more detail.

2 to 8 shows a preferred embodiment of the sterile pig breeding isolator according to the present invention.

As shown, the main body 30 is provided with a space for breeding sterile pigs therein. The main body portion 30 is provided with a case 31 which is a space for breeding sterile pigs therein, and a lower frame 33 configured to support and move the case 31 below the case 31. Is provided. The lower frame 33 may be provided with a plurality of moving wheels 35.

One surface of the case 31 is provided with a case window 37 made of a transparent material. It is possible to observe the state of the sterile pig inside the case 31 through the case window 37.

The case window 37 is provided with a plurality of gloves 39. The glove 39 is for allowing the experimenter or breeder to handle the animal in a sterile state without directly contacting the animal. A glove protection cover 41 may be further provided at the point where the glove 39 is provided to prevent damage of the glove 39 by an animal.

One surface of the case 31 is provided with a transfer unit 50. The transfer part 50 is for disinfecting an article carried into the case 31 or an article carried out from the case 31 to the outside.

The transfer part 50 is provided with an inner door 51 for selectively shielding one surface of the case 31. The inner door 51 may be packed around the door to keep the inside airtight, and as shown in a partially enlarged view of FIG. 2, the inner door 51 may be hermetically shielded. Fixing member 53 is provided.

The fixing member 53 may be configured as a catch (catch) to secure the door by pressing the door while rotating, it may be provided with a plurality around the inner door (51).

The transfer unit 50 may be provided with an outer cap 55 to disinfect the loaded or unloaded material in the outer cap 55. The outer cap 55 may also be provided with a separate opening and closing door.

The control box 57 of the lower frame 33 is provided with a supply / exhaust unit 60 for supplying / exhaust air into the case 31 as shown in FIG. 8. The air supply and exhaust unit 60 is provided with an air supply unit 70 for supplying air into the case 31.

The air supply unit 70 is provided with an air supply blower 71 for introducing external air into the case 31, and the air supply air blower 71 has a temperature of air introduced into the case 31. A heater 73 for holding is provided. In addition, the air supply unit 70 is provided with an air supply unit hepa filter 75 for maintaining the cleanliness of the air flowing into the case (31).

The air supply / exhaust unit 60 is also provided with an exhaust unit 80 for exhausting from the case 31. The exhaust unit 80 also includes an exhaust blower 81 for discharging air in the case 31 to the outside, and an exhaust unit HEPA filter for purifying air discharged to the outside of the case 31. 77 is provided. In addition, the exhaust unit 80 may be further provided with a pre-filter 83 which can be easily replaced.

As shown in FIG. 5, the air supply / exhaust unit 60 may further include a perforated plate 91 for evenly distributing air drawn from the air supply unit 70 into the case 31. The perforated plate 91 may be provided at the upper and lower portions of the case 31, respectively.

The perforated plate 91 is connected to a branch pipe (not shown) connecting the inside of the case 31 and the air supply unit 70. Therefore, the clean air introduced by the air supply unit 70 is delivered to the punching plate 91 along the branch pipe, and the clean air is evenly introduced into the case 31.

The isolator of the present invention is provided with a life support part 100 for preventing the death of sterile pig even in the case of power failure.

The air supply and exhaust unit 60 is driven by using an external power source in daily life. However, in the case of a power failure, since the external power is not supplied, the supply / exhaust part 60 may not be driven, so that the sterile pig inside the case 31 may be dead.

Therefore, the uninterruptible supply unit 101 is further provided to supply power even in a power failure to drive the air supply / exhaust unit 60. The uninterruptible power supply 101 may be configured as an uninterruptible power supply (UPS) battery. The uninterruptible supply unit 101 may prevent the death of sterile pigs by supplying power to the supply / exhaust unit 60 even when power is not supplied from the outside.

The life support part 100 is further provided with a safety filter 103. The safety filter 103 is provided on an upper surface of the case 31. The safety filter 103 is provided with a minimum HEPA filter or ULPA filter to prevent the sterilization of sterile pigs during power outages or even when the supply and exhaust unit 60 is fixed.

The control box 57 is provided with a controller 110 for controlling the state of the isolator. The control unit 110 is provided with a ventilation number control unit 110 for inputting and displaying the number of ventilation in the case (31).

Through the ventilation frequency control unit 110, the ventilation frequency inside the case 31 may be input. The PV of the ventilation frequency controller 110 displays the ventilation frequency set to ventilate the inside of the case 31, and the SV displays the current operating frequency of the case 31. Ventilation frequency is an important value related to the development and health of the sterile pigs in the case (31).

The control unit 110 is provided with a temperature control unit 113 for controlling the temperature of the air introduced into the case 31. The temperature control unit 113 is provided with a control selection unit 113a for selecting whether to control the temperature automatically or manually, and a temperature control unit 113b for adjusting the temperature of the air. .

The control unit 110 is further provided with a pressure display unit 115 for displaying the pressure in the case (31). Since the pressure inside the case 31 should always be maintained at a positive pressure, it may be checked whether the pressure is maintained at a positive pressure by the pressure display unit 115. The reason why the internal pressure of the case 31 should be maintained at a positive pressure (+) is because the inside of the case 31 must be maintained at a positive pressure (+) higher than the external pressure, so that outside air is not introduced into the inside Can be kept aseptic.

The control unit 110 is provided with a filter operation time display unit 117 for displaying the operating time of the HEPA filter (75, 77). Since the operation time of the HEPA filter 77 can be known through the filter operation time display unit 117, it is possible to know when to replace the HEPA filters 75 and 77. The control unit 110 may be provided with a separate reset button 119 to reset the time of the filter operation time display unit 117.

The isolator of the present invention is further provided with a management holding unit 120 for maintaining and managing the aseptic pig breeding space. The management holding unit 120 is provided with a bottom surface 121 configured to drop the droppings of sterile pigs raised in the case 31 downward. The aseptic pig droppings may fall downward on the bottom surface 121, but a gap is formed such that the aseptic pig does not fall downward.

The lower drain hopper 123 is provided below the case 31. The lower drain hopper 123 is formed narrower toward the lower portion serves to collect the droppings falling through the bottom surface 121.

The lower drain hopper 123 is provided with a lower drain 125 may discharge the excrement to the outside. The lower drain 125 may include a valve 127 to selectively discharge the excrement collected by the lower drain hopper 123 to the outside.

The management holding unit 120 is provided with a heat generating unit 129 for heating the inside of the case 31. The heat generating unit 129 may be configured as an infrared lamp, and may be provided at an upper side of the case 31. The heating unit 129 serves to improve the breeding conditions of sterile pigs by heating the inside of the case 31.

The management holding unit 120 is provided with a feed container 131 that can feed the sterile pigs in the case 31. Through the feed container 131, it is possible to supply a constant feed to the sterile pig.

The management holding unit 120 is further provided with a water supply unit 133. The water supply unit 133 is configured to receive water by the water supply tank 143 to be described below to be supplied to the sterile pig.

The management holding unit 120 is provided with a cleaning unit 135 for cleaning the inside of the case 31. The cleaning unit 135 may include a hose connected to the water supply tank 143 and a cleaning gun provided at the tip of the hose to clean the inside of the case 31. The cleaning unit 135 may be provided in a cleaning box 137 mounted on a part of the case 31 and selectively opened and closed.

The inner ceiling of the case 31 may be provided with a chain 141, which is an amusement device of sterile pig. Aseptic pigs can play with the chain 141 to obtain physical development and stress reduction effects.

The upper part of the case 31 is provided with a water supply tank 143 for supplying water to the water supply unit 133 and the cleaning unit 135. The water supply duct 145 is connected to the water supply tank 143 to store water supplied from the outside therein.

Hereinafter, the operation of the sterile pig breeding isolator according to the present invention having the configuration as described above in detail.

First, run the isolator and set the internal conditions. To set the set temperature of the temperature control unit 113 of the control unit 110, and press the reset button 119 to measure the use time of the filter.

Once the operating conditions of the isolator are set, the sterile pigs are brought into the case 31. The sterile pig is placed in the transfer part 50 and subjected to a predetermined disinfection, and then the inner door 51 is opened and brought into the case 31. In this case, the inner door 51 may be hermetically shielded by the fixing member 53 provided in the inner door 51.

When sterile pigs are brought into the case 31, the sterile pigs can be treated in a sterile state using the gloves 39 provided on one surface of the case 31. The air inside the case 31 may be purified by the HEPA filter 75 of the air supply unit 70 and heated by the heater 73 to satisfy an appropriate condition for growing sterile pigs. In addition, the air introduced into the case 31 is purified by the prefilter 83 and the HEPA filter 77 of the exhaust unit 80 and discharged to the outside.

When the power supplied to the air supply and exhaust unit 60 is cut off by a power failure, the uninterruptible supply unit 101 is automatically operated by the controller 110. Since the uninterruptible supply unit 101 may drive the supply / exhaust unit 60 by the charged electric power, the sterile pig inside the case 31 does not die even during a power failure. In addition, when the supply / exhaust part 60 is broken, since the case 31 is not sealed by the safety filter 103, it is possible to prevent the sterilization of the sterile pig.

In addition, feces generated while the sterile pigs are raised in the case 31 are collected by the lower drain hopper 123 by falling into the gap of the bottom surface 121 of the case 31. The excrement collected by the lower drain hopper 123 may be discharged to the outside by opening the valve 127 about once a day.

In addition, it is possible to constantly feed the sterile pigs by the feed container 131 of the management and maintenance unit 120, it is possible to supply water to the sterile pigs by the water supply unit 133 connected to the water tank 143. have.

Since the water stored in the water tank 143 is supplied to the cleaning unit 135, the inside of the case 31 may be cleaned. As the sterile pig can use the chain 141 provided on the ceiling of the case 31, the growth and the stress reduction effect of the sterile pig occur.

In addition, the pressure gauge 115 of the controller 110 may determine whether the inside of the case 31 is maintained at a positive (+) pressure, and the HEPA filter 75, through the filter operation time display unit 117. Since the uptime of the HEPA filters 75 and 77 can be exceeded, the operation time of the 77 can be replaced.

Within the scope of the basic technical idea of the present invention, many other modifications are possible to those skilled in the art, and the scope of the present invention is interpreted based on the utility model registration claims to be described later. Should be.

According to the aseptic pig breeding isolator according to the present invention as described in detail above has the following advantages.

The uninterruptible supply unit can drive the supply / exhaust unit even in the event of a power failure, and even if the supply / exhaust unit cannot be driven by the safety filter, the supply / exhaust can be supplied to the inside of the case. have.

Since the feces of sterile pigs raised in the case can be easily discharged to the lower drain, and the inside of the case can be cleaned by the cleaning unit, there is an advantage that the convenience of management is increased.

1 is a perspective view showing the appearance of an isolator according to the prior art.

Figure 2 is a perspective view showing the appearance of the sterile pig breeding isolator according to the present invention.

Figure 3 is a front view showing the front of the sterile pig breeding isolator according to the present invention.

Figure 4 is a rear view showing the rear of the aseptic pig breeding isolator according to the present invention.

Figure 5 is a transparent perspective view showing the bottom drain structure of the sterile pig breeding isolator according to the present invention.

Figure 6 is a front view showing the internal structure of the case of the sterile pig breeding isolator according to the present invention.

Figure 7 is a front view showing one side of the control box of the sterile pig breeding isolator according to the present invention.

8 is a schematic structural diagram showing the internal structure of the supply and exhaust of the aseptic pig breeding isolator according to the present invention.

    * Description of the main parts of the drawings *

30: main body 31: case

33: lower frame 37: case window

41: glove protective cover 50: transfer part

51; Inner door 55: outer cap

57: control box 70: air supply

71: air blower 73: heater

75: HEPA filter 81: exhaust fan

83: pre-filter 91: punched plate

103: safety filter 110: control unit

120: management and maintenance unit 141: chain

Claims (14)

A main body configured to maintain the interior in a sterile state; An air supply / exhaust unit provided in the main body unit and configured to introduce sterile air into the main body unit or to discharge internal air to the outside; A control unit controlling an operation of the supply / exhaust unit; A life support unit for supplying supplementary power when the supply / exhaust unit does not operate or inflowing external air in a sterile state so that the inside of the main body unit is not sealed; and Includes a management holding unit configured to manage the sterile pigs raised in the main body in a clean state, The life support unit An uninterruptible supply unit for supplying power to the supply / exhaust unit even in a power failure; It characterized in that it comprises a safety filter consisting of a HEPA filter or ULPA filter for introducing the outside air in a sterile state without being sealed inside the main body portion Sterile pig breeding isolators. delete The method of claim 1, The main body portion The case is provided with a glove on one side and configured to handle aseptic pigs from the outside, It characterized in that it comprises a lower frame for supporting the case and the supply and exhaust portion Sterile pig breeding isolators. The method of claim 3, The case is It characterized in that it comprises a transfer unit for entering and exiting the article to be introduced into the case aseptically Sterile pig breeding isolators. The method of claim 4, wherein The transfer unit An inner door to selectively open and close one surface of the case; Fixing member for fixing the inner door to shield the inside of the case; And And an outer cap providing a space for disinfecting the article entering and exiting the case. Sterile pig breeding isolators. The method of claim 1, The management holding unit A lower drain for selectively carrying out sterile pig droppings accumulated inside the case of the main body to the outside; It characterized in that it comprises a cleaning unit for cleaning the inside of the case by the water supplied from the outside Sterile pig breeding isolators. The method of claim 6, On the upper part of the lower drain and the bottom surface formed with a gap so that the feces of aseptic pig drop down; A lower drain hopper which collects the droppings falling to the bottom of the bottom surface into the inlet of the lower drain, A valve for opening and closing the lower drain is further provided. Sterile pig breeding isolators. The method of claim 6, The cleaning unit has a water tank for storing the water supplied from the outside, The water supply unit for receiving the water from the water supply tank to the inside of the case is further provided. Sterile pig breeding isolators. The method of claim 6, A heating unit for supplying heat to the inside of the case is characterized in that it is further provided Sterile pig breeding isolators. The method of claim 6, A chain is further provided inside the case. Sterile pig breeding isolators. The method of claim 1, The air supply unit of the air supply and exhaust unit, A blower for supplying air into the case; Hepa filter for purifying the air introduced into the case; And And a heater for heating air introduced into the case. Sterile pig breeding isolators. The method of claim 1, The exhaust part of the air supply and exhaust part, A blower for exhausting the air to the outside of the case; A prefilter for preliminarily purifying the air exhausted to the outside of the case; and And a hepa filter for purifying the air exhausted to the outside of the case. Sterile pig breeding isolators. The method of claim 11, The supply and exhaust unit And a perforated plate for evenly supplying air introduced by the air supply unit into the case. Sterile pig breeding isolators. The method of claim 1, The control unit, A ventilation frequency controller for inputting and displaying the ventilation frequency inside the case; A temperature controller for controlling a temperature of air introduced into the case; Filter operation time display unit for displaying the use time of the filter of the supply and exhaust unit; And And a pressure display unit for displaying the pressure inside the case. Sterile pig breeding isolators.

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