KR20040028448A - Beauty wash ingredients for prevented of skin trouble - Google Patents
Beauty wash ingredients for prevented of skin trouble Download PDFInfo
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- KR20040028448A KR20040028448A KR1020020059628A KR20020059628A KR20040028448A KR 20040028448 A KR20040028448 A KR 20040028448A KR 1020020059628 A KR1020020059628 A KR 1020020059628A KR 20020059628 A KR20020059628 A KR 20020059628A KR 20040028448 A KR20040028448 A KR 20040028448A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/413—Nanosized, i.e. having sizes below 100 nm
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Abstract
Description
본 발명은 여드름등 각종 피부 트러블 방지용 화장수 조성물에 관한 것으로, 더욱 상세하게는 나노 입자의 은을 정제수에 균일하게 분산시켜 몇 가지 보조제를 첨가하여 조성됨을 특징으로 하는 피부트러블 방지용 화장수 조성물에 관한 것이다.The present invention relates to various skin trouble prevention lotion compositions such as acne, and more particularly, to a skin trouble prevention lotion composition, characterized in that the silver particles of the nanoparticles are uniformly dispersed in purified water and added with a few supplements.
: 피부트러블은 몇 가지 원인이 있으며 내부적원인과 외부적원인이 있다. 그중 피부에 기생하는 모낭충(DEMODEX)와 여드름균(Propionibacterium Acnes) 등 균에 의한 내부적인 원인이 가장 주된 원인이다.: There are several causes of skin trouble and there are internal and external causes. Among them, the main causes are internal causes caused by bacteria such as DEMODEX and Acne bacteria (Propionibacterium Acnes).
o 즉 피부 트러블은 얼굴에 기생하는 모낭충(DEMODEX)와 여드름균(Propionibacterium Acnes)에 의해 일어나는데 특히, 모낭충(DEMODEX)의 경우 사람 97.8%가 보균하고 있으며 야행성으로 지방을 좋아하여 피부 모공속에 기생하며 피지를 영양분으로 하고 있다. 또한 유충에서 12시간 후 성충으로 자라며,한번에 50개의 알을 낳고 수명은 12일 정도 이다.o Skin problems are caused by DEMODEX and Propionibacterium Acnes, which are parasitic on the face, especially 97.8% of humans in DEMODEX, which are nocturnal and fond of skin because they like fat. Is nutrients. It also grows to adult after 12 hours in larva, lays 50 eggs at one time and has a lifespan of about 12 days.
따라서 피부 속에서 죽은 모낭충(DEMODEX)의 사체는 자연히 모공속에서 부패하여 피부 트러블의 원인으로 작용한다.Therefore, dead carcasses of DEMODEX in the skin naturally decay in the pores and act as a cause of skin troubles.
o 여드름균(Propionibacterium Acnes)의 경우 피부트러블의 일종인 여드름을 유발 시키는 혐기성 균으로 지성피부나 호르몬 분비가 왕성한 사춘기 피부에 많이 기생하며 여드름을 유발한다.o Acne bacteria (Propionibacterium Acnes) is an anaerobic bacterium that causes acne, a kind of skin trouble. It is parasitic on puberty skin with oily skin or hormone secretion and causes acne.
o 본 발명은 은이 갖고 있는 협충작용 및 세균 바이러스에 대한 살균력을 이용하여 인체에 전혀 해가없는 천연의 물질을 주 원료로 모낭충(DEMODEX)과 여드름균(Propionibacterium Acnes)등 피부에 기생하는 균을 살균하여 피부트러블의 원인을 제거함에 있으며, 특히 나노화된 은입자는 적은 은의 양으로도 충분한 효과를 발휘 할 수 있는 첨단 기술로서 첨가하는 몇가지 보조제는 피부재생에 도움을 주는 것으로 나타났다.o The present invention sterilizes the parasitic bacteria on the skin such as DEMODEX and Propionibacterium Acnes, using natural substances that are harmless to the human body, by using the bactericidal action against silver and bacterial viruses. In order to eliminate the cause of skin troubles, especially nano-silver particles have been shown to be a high-tech technology that can exert a sufficient effect even in a small amount of silver supplemental supplements have been shown to help skin regeneration.
o 따라서 본 발명의 목적은 위의 효과와 효능을 감안하여 피부트러블 방지용 화장수 조성물을 제공함에 있다.o Accordingly, an object of the present invention is to provide a skin trouble prevention composition in view of the above effects and efficacy.
o 본 발명은 피부트러블 방지용 화장수 조성물을 생산하여 실제 임상실험을 통하여 모낭충(DEMODEX)와 여드름균(Propionibacterium Acnes)에 대한 살충,살균 효과를 검증하였으며, 중금속 및 안전성 실험에서도 매우 안전하여 화장품원료로 적합하다는 판정을 받아 그목적을 달성하였다.o The present invention produced the skin trouble prevention lotion composition and verified the insecticidal and bactericidal effects on DEMODEX and Acne bacteria (Propionibacterium Acnes) through actual clinical experiments, and is very safe in heavy metals and safety experiments, suitable as a cosmetic raw material The objective was achieved.
o 이하 본 발명의 실시 예를 구체적인 구성 및 작용을 통하여 설명하지만 단순한 함량의 변경과 보조제의 종류를 바꿔 그 설계를 변경 할 수 있으나, 그 기술적 방법론은 본 발명에 속해 있는 것이다.o Hereinafter, embodiments of the present invention will be described through specific configurations and operations, but the design may be changed by simply changing the content and changing the type of adjuvant, but the technical methodology belongs to the present invention.
도 1은 본 발명 실시 예 화장수 조성물의 제조 공정도1 is a manufacturing process of the present invention embodiment cosmetic lotion composition
o 본 발명의 피부트러블 방지용 화장수 조성물은 나노(3-10NM) 입자화한 은을 정제수에 균일화게 분산시켜 몇 가지 보조제를 첨가하여 구성한 것이다o The skin trouble preventing skin composition of the present invention is composed of nano (3-10NM) granulated silver uniformly dispersed in purified water and adding some auxiliary agent.
o 본 발명에 사용되는 나노 입자의 은은 전기분해 방식으로 나노화 하며 이 과정중 물의 크기가 60Hz로 기존의 일반 용수의 120Hz보다 작게 하며 산도는 약 7.4정도로 인체와 적합하며 피부에 잘 흡수 될 수 있는 형태를 띤다.o The silver nanoparticles used in the present invention are nanonized by electrolysis. During this process, the water size is 60Hz, which is smaller than 120Hz of conventional water, and the acidity is about 7.4. It takes
o 본 발명의 주재료인 나노 입자화 된 은은 그 자체의 브라운운동으로 별도의 안정제(Stabilizer)가 필요 없다는 장점과 천연의 재료로 인한 환경오염 방지의 장점이 있다.o The nano-grained silver which is the main material of the present invention has the advantage of not requiring a separate stabilizer (Stabilizer) due to its own brown motion and preventing the environmental pollution due to natural materials.
o 이하 본 발명의 실재 조성의 실시 예를 들어 설명하고자 한다.o Hereinafter will be described with reference to the embodiment of the actual composition of the present invention.
-표 1.Table 1.
나노 은용액 90.66 중량 % 알로에 베라 5.00 중량 %Nano Silver Solution 90.66 wt% Aloe Vera 5.00 wt%
에타놀 4.00 중량 % 디엠디엠히단토인 0.10 중량 %Ethanol 4.00 wt% DMDM Hydantoin 0.10 wt%
폴리소르베이트 80 0.10 중량 % 케스토르 오일 0.07 중량 %Polysorbate 80 0.10 wt% Kestor Oil 0.07 wt%
조합향 0.05 중량 % 에칠렌디아민테트라초산디나트륨 0.02Combination fragrance 0.05 wt% ethylenediaminetetraacetate acetate 0.02
중량 %weight %
o 상기 실시 예 제품의 PH는 7.4±0.2로 측정 되었다.o The pH of the example product was measured to be 7.4 ± 0.2.
o 상기 실시 예 제품을 실험에 참가한 사람들의 얼굴 T-Zone부위에서 아크네퓨샤를 이용하여 모낭충(DEMODEX)를 채취하여 피부트러블 방지용 화장수 조성물 투하실험과 통상 치사 시험을 실시하여 본 발명 화장수가 모낭충(DEMODEX) 살균에 미치는 영향을 실험하였다.o Demodex insects (DEMODEX) were collected using the Acne Fuchsia from the face T-Zone of the people who participated in the experiment, and the skin lotion composition drop test and normal lethal test of the skin trouble were carried out. ) The effect on sterilization was tested.
o 실험표본 5명에게서 (1명당 모낭충 1마리 이상)을 채취하여 식용유를 적당히 투입한 슬라이드 그라스에 아크네퓨사로 채취한 피지를 잘 각반하여 현미경(80x10배)으로 살아 있는 모낭충을 발견하여 본 발명 화장수를 미량 투여 하였다. 5명에게서 채취한 모낭충의 평균 치사 시간은 14분정도 이며, 통상 치사 시간은 2시간 이상으로 확실한 살충효과를 알 수 있었다.o The specimens were collected from five test specimens (one or more Demodex insects per person), and the living glassworms were found under a microscope (80x10x) by finding the living sebums with a microscope (80x10x). A small dose was administered. The average mortality time of hair follicles collected from five patients was about 14 minutes, and the normal mortality time was more than 2 hours.
-표2,3Tables 2 and 3
o 또한 여드름균(Propionibacterium Acnes)활성 억제 효과 실험을 Paper Disc법에 의해 여름균에 억제효과가 탁월하다고 입증된 티트리오일과 대비 실험을 실시하여 그 효과를 대비 실험해 보았다.o In addition, experiments were conducted to compare the effects of tea tree oil, which was proved to be superior to summer bacteria by the Paper Disc method.
o 시험균주는 -70℃로 보관중인 Propionibacterium Acnes KCTC 3314를 이용하였으며, 증식은 BECTON DICKINSON사 (USA)의 BHI(Brain Herrt Infusion)broth(액상스프)를 사용하였고 혐기성배양을 위한 협기조는 BECTON DICKINSON사 (USA)의 GasPak 100을 사용하였다.o The test strain was Propionibacterium Acnes KCTC 3314 stored at -70 ° C, BECTON DICKINSON (USA) BHI (Brain Herrt Infusion) broth (liquid soup) was used, and BECTON DICKINSON for anaerobic culture GasPak 100 from the USA (USA) was used.
o 각각 시료 물질을 멸균된 Paper Disc(시판함,직경 10mm이내)에 0.1g씩 점적한 후, 준비된 BHI agar 평판배지에 부착하여 3일 이상 혐기성 배양조에 배양하여 clear zone의 직경을 측정하여 상대 평가한 결과 본 발명 화장수의 월등한 살균효과를 알수 있었다.o Each sample material was instilled in a sterilized paper disc (commercially available box, less than 10mm in diameter) by 0.1g, and then attached to the prepared BHI agar plate medium and incubated in an anaerobic culture vessel for at least 3 days to measure the diameter of the clear zone for relative evaluation. As a result, the superior bactericidal effect of the present invention lotion was found.
-표4Table 4
o 아울러 피부사상균 살균 실험도 실시하였으며, 피부사상균이 번식하면 각질이 과도하게 일어나고 가려움증이 유발한다. 그러나 본 발명 시료는 피부사상균 성장을 억제해 각질을 제거하여 피부트러블을 없애는데 효과적인 것을 알 수 있다..o In addition, the bacteriophage sterilization experiment was conducted. When the bacterium grows, excessive keratin occurs and itching is caused. However, it can be seen that the sample of the present invention is effective in eliminating the skin trouble by inhibiting the growth of dermatophytes.
-표5Table 5
o 본 발명 시료 실시 예 제품의 안전성 실험과 중금속 실험을 실시하였다o Safety experiments and heavy metal experiments were performed on the sample examples of the present invention.
-표6,7Table 6,7
o 본 실험에 참여 한 9명에게서 피부에 어떠한 부작용도 발견 되지 않았다.o No adverse effects on skin were found in the nine subjects.
[표1]Table 1
[2] 모낭충(DEMODEX) 살균 실험(본 발명 조성 화장수 투하실험 결과) [2] Demodex sterilization test (the result of the present invention cosmetic lotion drop test)
[3] 모낭충(DEMODEX) 살균 시험(통상 치사 실험) [3] DEMODEX sterilization test (normally lethal test)
[4] 여드름균(Propionibacterium Acnes)활성 억제 효과 실험[4] Inhibitory Effects of Propionibacterium Acnes
[5] 피부사상균 살균 실험[5] sterilization experiments
[6] 중금속 시험[6] heavy metal testing
[7] 안전성 검사[7] safety checks
o 상기 실시 예의 실험 결과를 통하여 확인한 바와 같이 본 발명은 나노입자의 은용액을 주재료로 한 피부트러블 방지용 화장수 조성물은 피부에 기생하는 기생충 및 세균에 대한 뛰어난 살균효과로 각종 피부트러블의 원인을 근본적으로 제거하여 국민건강 증진과 화장품산업의 발전에 매우 유용할 것이다.o As confirmed through the experimental results of the above embodiment, the present invention is a skin trouble prevention cosmetic composition mainly composed of silver particles of nanoparticles, which has a fundamental antiseptic effect on parasites and bacteria that are parasitic on the skin. It will be very useful for the promotion of national health and the development of the cosmetic industry.
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Cited By (3)
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| WO2006025637A1 (en) * | 2004-08-28 | 2006-03-09 | Nano Plasma Center Co., Ltd. | Gold or silver particles with paramagnetism, and composition conatining thereof |
| KR100569857B1 (en) * | 2004-09-07 | 2006-04-11 | 배성태 | Aromawater manufacture method that silver-nano is contained |
| CN103735465A (en) * | 2014-01-15 | 2014-04-23 | 张一文 | Child floral water and preparation method thereof |
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| WO2006025637A1 (en) * | 2004-08-28 | 2006-03-09 | Nano Plasma Center Co., Ltd. | Gold or silver particles with paramagnetism, and composition conatining thereof |
| KR100569857B1 (en) * | 2004-09-07 | 2006-04-11 | 배성태 | Aromawater manufacture method that silver-nano is contained |
| CN103735465A (en) * | 2014-01-15 | 2014-04-23 | 张一文 | Child floral water and preparation method thereof |
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