KR20030023394A - Liquid detergent composition for infant - Google Patents

Abstract

PURPOSE: A liquid detergent composition for babies is provided, which shows exhibits improved cleansing powder, an antibacterial effect without irritating the skin and a low viscosity and generates no insoluble precipitate causing the irritation to skin. CONSTITUTION: The liquid detergent composition comprises 1-6 wt% of a secondary alkanesulfonate of C12-C18 and 3-10 wt% of polyoxyethylene ether sulfate ester of C10-C18 with an ethylene oxide addition amount of 3-5 as an anionic surfactant; 5-15 wt% of an alkyl polyoxyethylene ether of C10-C18 with an ethylene oxide addition amount of 7-15 and 5-15 wt% of alkyl dimethylamine oxide of C10C14 as a nonionic surfactant; 1-8 wt% of hydrotrope; 0.1-2 wt% of an antibacterial agent; 0.1-5 wt% of a skin irritation relieving agent; 0.1-5 wt% of a water-soluble cleansing power enhancer; and the balance of water. Preferably the antibacterial agent is a polyhexamethylene guanidine salt derivative; and the skin irritation relieving agent is the extract of Portulaca oleracea L.

Description

Liquid detergent composition for infants {LIQUID DETERGENT COMPOSITION FOR INFANT}

The present invention relates to a liquid detergent composition for infants, and more particularly to a liquid detergent composition for infants suitable for use in children's clothing and children's clothing because it does not irritate the skin and excellent sterilization.

In general, liquid detergent has the advantage of convenient weighing and dust does not fly compared to the powder detergent, there is no problem of agglomeration such as powder detergent during storage.

However, liquid detergents are known to have poor cleaning performance compared to powder or granule formulations due to the limitation of the formulation. The reason why the liquid detergent is poor in cleaning performance is that in the case of the powder detergent, a high concentration of the cleaning agent (metal ion blocker) and the alkaline agent can be accommodated, whereas the liquid detergent is used in combination with the surfactant for reasons of phase stability and safety of use. This is because it cannot contain a high concentration of an enhancer and an alkali.

Therefore, the general liquid detergents have a problem that the cleaning power is deteriorated with the disadvantage of using an excessive amount compared to the powder detergent, in particular, it is difficult to have a satisfactory cleaning power, such as infant clothing and diapers with a high cotton content.

In addition, the general liquid detergents do not contain an enhancer, so calcium ions and magnesium ions in water lower the washing power when washing, and when the insoluble substances are left in the clothing, skin irritation occurs.

Therefore, the existing liquid detergents were not suitable for use in infants.

In addition, since the conventional liquid detergent does not contain a disinfectant, bacteria may remain even after washing, which may result in unsanitary washing. To improve this, liquid detergent compositions containing hydroxyacetic acid, phenol derivatives, and trichlorocarbanilide (TCC), respectively, have been proposed, but these liquid detergent compositions do not show satisfactory bactericidal power and are irritating to the skin and thus are used as infant products. Not suitable for use

Accordingly, the present invention, in consideration of the problems of the prior art as described above, is an object of the present invention to provide a liquid detergent composition for infants having excellent cleaning power and a sterilizing effect of laundry without irritating the skin compared to other conventional liquid detergents. do.

Another object of the present invention is to provide a low viscosity liquid detergent composition which is convenient to use without forming an insoluble precipitate that causes irritation.

In order to achieve the above object, the present invention provides a liquid detergent composition for infants,

a) 1 to 6% by weight of a secondary alkanesulfonate having 12 to 18 carbon atoms as anionic surfactant, and 3 to 10% by weight of polyoxyethylene ether sulfate ester salt having 10 to 18 carbon atoms having 3 to 5 ethylene oxide addition amounts;

b) 5 to 15% by weight of an alkylpolyoxyethylene ether having 10 to 18 carbon atoms and 7 to 15% by weight of an alkyldimethyl amine oxide having 10 to 14 carbon atoms having an ethylene oxide addition amount of 7 to 15 as a nonionic surfactant;

c) 1 to 8% by weight of hydrotropes;

d) 0.1 to 2 weight percent fungicide;

e) 0.1 to 5% by weight of skin irritant;

f) 0.1 to 5 weight percent of a water soluble laundry enhancer; And

g) remaining water

It provides a baby liquid detergent composition comprising a.

Hereinafter, the present invention will be described in detail.

In general, when the anionic surfactant and nonionic surfactant are properly mixed in the liquid detergent composition, excellent washing power can be expected. However, in the case of anionic surfactants, washing ability is excellent, but skin irritation is greater than nonionic surfactants, so it is important to appropriately adjust the amount used to minimize skin irritation and increase washing power.

Therefore, the present inventors can maximize the cleaning power by adjusting the amount used to minimize the skin irritation of anionic surfactant and increase the washing power, and include the water-soluble laundry enhancer and the buffer therein, and also the skin irritation with excellent sterilizing power. The present invention was confirmed that the use of a very low level of fungicide and the addition of a plant extract having a property of alleviating skin irritation can provide a liquid detergent composition for infants that is much hypoallergenic than other liquid detergents. .

The infant liquid detergent composition of the present invention includes an anionic surfactant and a nonionic surfactant as a surfactant. The total amount of the surfactant is preferably 10 to 50% by weight with respect to the composition, more preferably 15 to 40% by weight. When the amount of the surfactant is less than 15% by weight, it is difficult to expect sufficient washing power, and when it exceeds 40% by weight, skin irritation may occur, the viscosity may increase, and the liquid detergent composition may be unstable.

The anionic surfactants include secondary alkanesulfonates having 12 to 18 carbon atoms, polyoxyethylene ether sulfate ester salts having 10 to 18 carbon atoms having an ethylene oxide addition amount of 3 to 5, and preferably secondary secondary alkanesulfonic acid salts. It is preferable to mix and use a polyoxyethylene ether sulfate ester salt. The secondary alkanesulfonic acid salt is used in an amount of 1 to 6% by weight, and polyoxyethylene ether sulfate ester salt is used in an amount of 3 to 10% by weight. If the amount of the secondary alkane sulfonate is less than 1% by weight, the washing power is lowered. If the amount of the secondary alkanesulfonate is more than 6% by weight, skin irritation is increased. If the amount of the polyoxyethylene ether sulfate ester salt is less than 3% by weight, the washing power is lowered, and if it exceeds 10% by weight, there is a problem that skin irritation is increased.

In addition, the nonionic surfactants include alkyl polyoxyethylene ethers having 10 to 18 carbon atoms and alkyldimethyl amine oxides having 10 to 14 carbon atoms having an ethylene oxide addition amount of 7 to 15, and preferably 7 to 15 ethylene oxide addition amounts. It is preferable to use a mixture of phosphorus C10-C18 alkyl polyoxyethylene ether and C10-C14 alkyldimethyl amine oxide. In the case of the alkyl polyoxyethylene ether, when the molecular weight of the ethylene oxide added thereto is less than 7 molecules or more than 15 molecules, the phase stability at low temperature may be remarkably inferior or the washing power may not reach the level required by the present invention.

It is preferable that the usage-amount of the said alkyl polyoxyethylene ether is 5-15 weight%, and the usage-amount of an alkyl dimethyl amine oxide is 5-15 weight%. When the amount of each of the alkylpolyoxyethylene ether and the alkyldimethyl amine oxide is out of the above ranges, it is difficult to expect excellent washing power.

Infant liquid detergent composition of the present invention comprises a hydrotrope (Hydrotrope). As the hydroprop agent, ethylene glycol or propylene glycol is preferably used. The amount of the hydrotropes is preferably used in an amount of 1 to 8% by weight. If the amount of the hydrotropes is less than 1% by weight, it is difficult to expect the effect as a hydrotrope. It is difficult to expect sufficient cleaning power.

In addition, the baby liquid detergent composition of the present invention includes a fungicide having excellent antibacterial performance and low toxicity. The fungicide is preferably a polyhexamethylene guanidine salt derivative (SKYBIO 1125 from SK Chemicals). The amount of the disinfectant used is preferably 0.1 to 2.0 wt%, more preferably 0.8 to 2.0 wt%. If the amount of the disinfectant is less than 0.1% by weight, it is difficult to expect sufficient antimicrobial activity, and if it exceeds 2.0% by weight, problems such as cost increase and formulation and stability may occur.

Infant liquid detergent composition of the present invention comprises a plant extract having a property of alleviating skin irritation as a skin irritation relief agent. The plant extract used as the skin stimulant alleviator is preferably a portage extract. The amount of the skin stimulant alleviator preferably contains 0.1 to 5% by weight of silver. When the skin stimulant is used less than 0.1% by weight, it is difficult to expect a sufficient skin stimulation alleviation effect. And problems such as stability.

In addition, the infant liquid detergent composition of the present invention includes a water-soluble laundry enhancer that is a soluble polymer. The water soluble laundry enhancer is an air containing nitrilotriacetate, sodium or potassium tripolyphosphate, tetrasodium or tetrapotassium pyrophosphate, soluble citrate salts, alkoyl taurate, alkoyl isethionate, polymeric acrylate or acrylic components. Known compounds selected from the group consisting of a coalescing system and a zeolite acting as an ion exchange resin can be used. The optimum concentration of the water-soluble laundry enhancer can be adjusted according to the selected enhancer, but the amount of the water-soluble laundry enhancer is preferably 0.1 to 5% by weight. Exceeding the weight percent causes formulation and stability problems.

Infant liquid detergent composition of the present invention comprises water as the remaining components in addition to the above components.

In addition, the infant liquid detergent composition of the present invention may further include an additive which can be generally used in the liquid detergent composition. The additive is preferably at least one selected from the group consisting of pH adjusters, softeners, dirt suspensions, viscosity improvers, optical brighteners, and fragrances. It is preferable that the usage-amount of such an additive is 0.1 to 10 weight%.

The pH of the liquid liquid detergent composition for infants of the present invention depends on the selected specific component, and is selected to maintain the desired stability, it is preferable to adjust the degree of neutral to weak alkali about 6 to 13 in consideration of washing ability and skin irritation. The pH adjustment is controlled using an acid or base commonly used, preferably sodium hydroxide or citric acid.

Hereinafter, the present invention will be described in more detail based on the following examples. However, the following examples are provided to help the understanding of the present invention, and the scope of the present invention is not limited thereto.

[Examples 1-2 and Comparative Examples 1-2]

Infant liquid detergent compositions of Examples 1 and 2 and Comparative Examples 1 and 2 were prepared according to the component ratios shown in Table 1 below.

division Example 1 Example 2 Comparative Example 1 Comparative Example 2 Ingredients (% by weight) AES ¹ 5 12 5 12 SAS ² 3 8 3 8 AE ³ 10 6 10 6 AO ⁴ 12 8 12 8 PG ⁵ 6 3 6 3 Disinfectants ⁶ One One - - March extract 2 2 - - Laundry Intensifier ⁷ 4 4 - - Additive ⁸ 0.8 0.8 0.8 0.8 water Remaining amount Remaining amount Remaining amount Remaining amount

week)

1. AES: Polyoxyethylene ether sulfate ester salt of higher alcohol (EO 3 or 5)

2.SAS: 2nd class alkanesulfonate

3. AE: Alkyl polyoxyethylene ether (EO 10-15)

4. AO: Alkyldimethyl amine oxide

5. PG: Propylene Glycol

6. Disinfectant: SKYBIO 1125 (SK Chemical)

7. Laundry enhancer: 1: 3 mixture of nitrilotriacetate and soluble citrate salts

8. Additives: fragrances, defoamers etc.

Experimental Example 1

The washing power was tested in the following manners with respect to Examples 1 and 2 and Comparative Examples 1 and 2.

Cleaning power

Washing power experiment was performed as follows. First of all, the washing machine used TERG-OTOMETER, and cotton (EMPA-116) and cotton / polyester (WFK 20D) fabrics were used as stain cloths. Washing solution was prepared by adding 133 mg / L of calcium chloride to 1 L of distilled water and then adding 1 ml / L of the compositions of Examples 1 and 2 and Comparative Examples 1 and 2, was applied to the contaminated cloth at 20 ℃ After washing for 10 minutes, rinsed twice for 3 minutes, the washing power was evaluated by measuring the reflectance after the cloth and the washing by Equation 1 below, and the results are shown in Table 2 below.

[Equation 1]

division Example 1 Example 2 Comparative Example 1 Comparative Example 2 Cleaning power Polyester (EMPA-116) 12.9 16 10.0 12 Cotton (WFK20D) 38.9 40.1 34.2 35.1

In Table 2, in the case of Examples 1 and 2 it was found to have an excellent cleaning power compared to Comparative Examples 1 and 2 without the addition of a laundry enhancer in polyester and cotton fabrics.

[Examples 3 to 6 and Comparative Example 3]

By using the components used in Examples 1 and 2, the contents of the infant liquid detergent compositions of Examples 3 to 6 and Comparative Example 3 were prepared as shown in Table 3 below.

division Example 3 Example 4 Example 5 Example 6 Comparative Example 3 Ingredients (% by weight) AES ¹ 5 12 5 12 12 SAS ² 3 8 3 3 8 AE ³ 10 6 10 10 6 AO ⁴ 12 8 12 12 8 PG ⁵ 6 3 6 6 3 Disinfectants ⁶ One One 0.5 0.1 - March extract 2 2 - - - Laundry Intensifier ⁷ 4 4 4 4 4 Additive ⁸ 0.8 0.8 0.8 0.8 0.8 water Remaining amount Remaining amount Remaining amount Remaining amount Remaining amount

NOTE 1 to 8 components: as used in Examples 1 and 2 above.

Experimental Example 2

The bactericidal power of the liquid detergent compositions of Examples 3 to 6 and Comparative Example 3 was tested in the following manner.

Bactericidal power

E. coli , S. aureus , E. faecalis and B. ammoniagenes were selected as test strains, and then cultured for one day in the medium. Incubation and inoculation resulted in OD560 = 0.5-1.0.

960 ml of sterilized distilled water was inoculated into a washing device TERG-OTOMETER, inoculated with 40 ml of cultured microorganisms, and 1 g of each of the compositions of Examples 3 to 6 and Comparative Example 3 was added thereto, washed for 10 minutes, and a predetermined amount of detergent solution was collected. After incubation to evaluate the bactericidal power, the results are shown in Table 4 below.

The bactericidal power was evaluated in four steps as follows.

◎: 90% or more germicidal power ○: 70% or more germicidal power

△: 50% or more of sterilizing power, x: 50% or less of sterilizing power

ingredient Example 3 Example 4 Example 5 Example 6 Comparative Example 3 E. coli ◎ ◎ ○ ○ × S. aureus ◎ ◎ ○ ○ × E. faecalis ◎ ◎ ◎ ◎ × B. ammoniagenes ◎ ◎ ◎ ◎ ×

As can be seen from the results of Table 4, Examples 3 to 6 in the case of using the SKYBIO 1125 as a disinfectant exhibited excellent sterilizing power, in particular if included in the detergent composition more than 0.8% by weight as shown in Examples 3 and 4 Better sterilization effect was obtained.

[Examples 7 to 8 and Comparative Examples 4 to 5]

Infant liquid detergent compositions of Examples 7 to 8 and Comparative Examples 4 to 5 were prepared by varying contents using the components used in Examples 1 to 2 as shown in Table 5 below.

In this case, in the case of Comparative Examples 6 to 7, even if the extract is not added or added to the liquid detergent composition for infants using less nonionic surfactant compared to the anionic surfactant.

division Example 7 Example 8 Comparative Example 4 Comparative Example 5 Ingredients (% by weight) AES ¹ 5 5 12 12 SAS ² 3 3 8 8 AE ³ 10 10 6 6 AO ⁴ 12 12 8 8 PG ⁵ 6 6 3 3 Disinfectants ⁶ One One One One March extract 2 - 2 - Laundry Intensifier ⁷ 4 4 4 4 Additive ⁸ 0.5 0.5 0.5 0.5 water Remaining amount Remaining amount Remaining amount Remaining amount

NOTE 1 to 8 components: as used in Examples 1 and 2 above.

Experimental Example 3

Skin irritation tests were performed on the liquid detergent compositions of Examples 7 to 8 and Comparative Examples 4 to 5 in the following manner.

Skin irritation test

According to the Food and Drug Administration's SOP “Animal Skin Primary Stimulation Test”, the rabbits were fixed after removing hair on the back of each animal 24 hours before applying the test substance using a male rabbit weighing 3.0 ± 0.5 kg. Fixed to the vessel. Four test sites were determined about 2 × 2 cm in size up, down, left and right around the spine. The rubbing part was set up, and the abrasion part was cut to the stratum corneum using two needles. Among them, one part of abrasion and a part of rubbing and skin were used as the control compartment. Saline was used as a control material, and 0.5 g of the 50% solution of the detergent composition of Examples 7 to 8 and Comparative Examples 4 to 5 was applied to the test site as test materials. 24 hours and 72 hours after application of the test substance was observed divided into erythema, skin and edema, and the degree of skin irritation was determined by PII (Primary irritation index) according to Equation 2 below It was determined based on the skin primary irritation table.

[Equation 2]

The final judgment was n = 4, divided into friction and non-friction parts after 24 hours and 72 hours, giving 0-4 points when erythema and skin were formed, and 0-4 points respectively depending on whether edema was formed. Calculated by The results are shown in Table 7 below.

Skin Primary Stimulation Table evaluation Safety classification Skin Primary Stimulation Index (P.I.I.) ◎ ○ △ × 0 to 0.50.6 to 2.02.1 to 5.05.1 or more Non irritant Mildly irritant Moderately irritant Severely irritant

ingredient Example 7 Example 8 Comparative Example 4 Comparative Example 5 Skin irritation evaluation ◎ ○ △ △

In Table 7, it can be seen that Examples 7 and 8 have less skin irritation than Comparative Examples 4 and 5. In particular, as shown in Example 7, when the extract of Machi Prefecture showed a higher effect of skin irritation compared to Comparative Example 5 without the addition of Machi Porta extract. That is, in Example 7, it can be seen that the skin irritation is less compared to Comparative Examples 4 and 5 using less nonionic surfactants than the anionic surfactants, and skin irritation is alleviated when the extract is used.

As described above, the infant liquid detergent composition of the present invention has excellent washing power compared to the conventional liquid detergent, has a sterilizing effect of laundry without irritating the skin, and is easy to use without forming an insoluble precipitate that causes irritation. It has the effect of showing a convenient low viscosity.

Claims (7)

In the baby liquid detergent composition, a) 1 to 6% by weight of a secondary alkanesulfonate having 12 to 18 carbon atoms as anionic surfactant, and 3 to 10% by weight of polyoxyethylene ether sulfate ester salt having 10 to 18 carbon atoms having 3 to 5 ethylene oxide addition amounts; b) 5 to 15% by weight of an alkylpolyoxyethylene ether having 10 to 18 carbon atoms and 7 to 15% by weight of an alkyldimethyl amine oxide having 10 to 14 carbon atoms having an ethylene oxide addition amount of 7 to 15 as a nonionic surfactant; c) 1 to 8% by weight of hydrotropes; d) 0.1 to 2 weight percent fungicide; e) 0.1 to 5% by weight of skin irritant; f) 0.1 to 5 weight percent of a water soluble laundry enhancer; And g) water as rest Infant liquid detergent composition comprising a. The infant liquid detergent composition according to claim 1, wherein the fungicide is a polyhexamethylene guanidine salt derivative. The liquid detergent composition according to claim 1, wherein the skin irritation mitigating agent is a Portugese extract. The method of claim 1 wherein the water soluble laundry enhancer is nitrilotriacetate, sodium or potassium tripolyphosphate, tetrasodium or tetrapotassium pyrophosphate, soluble citrate salts, alkoyl taurate, alkoyl isethionate, polymeric acrylate or Infant liquid detergent composition selected from the group consisting of a copolymer system containing an acrylic component, and a zeolite acting as an ion exchange resin. The infant liquid detergent composition according to claim 1, wherein the content of the surfactant including the anionic surfactant and the nonionic surfactant is 10 to 50% by weight. The infant liquid detergent composition according to claim 1, wherein the hydrotrope agent is ethylene glycol or propylene glycol. The infant liquid detergent composition of claim 1, wherein the infant liquid detergent composition further comprises at least one additive selected from the group consisting of a pH adjuster, a softener, a dirt suspension, a viscosity improver, a fluorescent brightener, and a perfume.