KR20020009610A - 매트릭스 메탈로프로테아제 억제제로서의 히드록삼산 유도체 - Google Patents
매트릭스 메탈로프로테아제 억제제로서의 히드록삼산 유도체 Download PDFInfo
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- KR20020009610A KR20020009610A KR1020017014418A KR20017014418A KR20020009610A KR 20020009610 A KR20020009610 A KR 20020009610A KR 1020017014418 A KR1020017014418 A KR 1020017014418A KR 20017014418 A KR20017014418 A KR 20017014418A KR 20020009610 A KR20020009610 A KR 20020009610A
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- UQIVBUOGGTYCHB-UHFFFAOYSA-N CCCC(CCc1ccncc1)CCNS(c1c(C(NO)=O)c(OC)ccc1)(=O)=O Chemical compound CCCC(CCc1ccncc1)CCNS(c1c(C(NO)=O)c(OC)ccc1)(=O)=O UQIVBUOGGTYCHB-UHFFFAOYSA-N 0.000 description 1
- PQEDZVHMHBLICN-UHFFFAOYSA-N COC(C1C(NO)=O)=CC=CC1S(N(CC1)CCC1Oc(cc1)cc2c1OCO2)(=O)=O Chemical compound COC(C1C(NO)=O)=CC=CC1S(N(CC1)CCC1Oc(cc1)cc2c1OCO2)(=O)=O PQEDZVHMHBLICN-UHFFFAOYSA-N 0.000 description 1
- 0 COc(cc1)ccc1OC(CC1)CCN1S(c1c(C(NO)=O)c(OC)ccc1)(=*)=O Chemical compound COc(cc1)ccc1OC(CC1)CCN1S(c1c(C(NO)=O)c(OC)ccc1)(=*)=O 0.000 description 1
- MYTHLYPHHKGKIC-UHFFFAOYSA-N COc1c(C(NO)=O)c(S(N(CC2)CCC2Oc(cc2)ccc2OC(F)(F)F)(=O)=O)ccc1 Chemical compound COc1c(C(NO)=O)c(S(N(CC2)CCC2Oc(cc2)ccc2OC(F)(F)F)(=O)=O)ccc1 MYTHLYPHHKGKIC-UHFFFAOYSA-N 0.000 description 1
- ZRPAZDPTLCHDRB-UHFFFAOYSA-N COc1cccc(S(N(CC2)CCC2Oc2ccc(C(F)(F)F)cc2)(=O)=O)c1C(NO)=O Chemical compound COc1cccc(S(N(CC2)CCC2Oc2ccc(C(F)(F)F)cc2)(=O)=O)c1C(NO)=O ZRPAZDPTLCHDRB-UHFFFAOYSA-N 0.000 description 1
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- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31081399A | 1999-05-12 | 1999-05-12 | |
US09/310,813 | 1999-05-12 | ||
PCT/US2000/006713 WO2000069819A1 (en) | 1999-05-12 | 2000-05-12 | Hydroxamic acid derivatives as matrix metalloprotease inhibitors |
Publications (1)
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KR20020009610A true KR20020009610A (ko) | 2002-02-01 |
Family
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Family Applications (1)
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KR1020017014418A KR20020009610A (ko) | 1999-05-12 | 2000-05-12 | 매트릭스 메탈로프로테아제 억제제로서의 히드록삼산 유도체 |
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EP (1) | EP1177173A1 (es) |
JP (1) | JP2002544257A (es) |
KR (1) | KR20020009610A (es) |
CN (1) | CN1360577A (es) |
AR (1) | AR035624A1 (es) |
AU (1) | AU781339B2 (es) |
BR (1) | BR0011291A (es) |
CA (1) | CA2373500A1 (es) |
HK (1) | HK1045501A1 (es) |
MX (1) | MXPA01011481A (es) |
NZ (1) | NZ515197A (es) |
WO (1) | WO2000069819A1 (es) |
ZA (1) | ZA200109007B (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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KR100621480B1 (ko) * | 2005-03-16 | 2006-09-19 | 최우혁 | 쇄미 선별 제거장치 |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6747027B1 (en) | 1996-07-22 | 2004-06-08 | Pharmacia Corporation | Thiol sulfonamide metalloprotease inhibitors |
US6696449B2 (en) | 1997-03-04 | 2004-02-24 | Pharmacia Corporation | Sulfonyl aryl hydroxamates and their use as matrix metalloprotease inhibitors |
US7115632B1 (en) | 1999-05-12 | 2006-10-03 | G. D. Searle & Co. | Sulfonyl aryl or heteroaryl hydroxamic acid compounds |
US6800646B1 (en) | 1999-02-08 | 2004-10-05 | Pharmacia Corporation | Sulfamato hydroxamic acid metalloprotease inhibitor |
WO2000056704A1 (en) * | 1999-03-22 | 2000-09-28 | Darwin Discovery Limited | Hydroxamic and carboxylic acid derivatives |
WO2001038322A1 (en) | 1999-11-23 | 2001-05-31 | Methylgene, Inc. | Inhibitors of histone deacetylase |
EP1598067B1 (en) | 2000-09-29 | 2009-05-06 | TopoTarget UK Limited | Carbamic acid compounds comprising an amide linkage for the treatment of malaria |
AU2001290131B2 (en) | 2000-09-29 | 2007-11-15 | Topotarget Uk Limited | Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors |
US6683078B2 (en) | 2001-07-19 | 2004-01-27 | Pharmacia Corporation | Use of sulfonyl aryl or heteroaryl hydroxamic acids and derivatives thereof as aggrecanase inhibitors |
CA2465328C (en) * | 2001-11-01 | 2011-06-14 | Michael Francis Gross | Piperidines |
NZ536116A (en) | 2002-04-03 | 2007-01-26 | Topotarget Uk Ltd | Carbamic acid compounds comprising a piperazine linkage as HDAC inhibitors |
AU2003221786A1 (en) | 2002-04-25 | 2003-11-10 | Pharmacia Corporation | Piperidinyl-and piperazinyl-sulfonylmethyl hydroxamic acids and their use as protease inhibitors |
WO2004065354A1 (en) | 2003-01-17 | 2004-08-05 | Topotarget Uk Limited | Carbamic acid compounds comprising an ester or ketone linkage as hdac inhibitors |
EP1866298A2 (en) * | 2005-03-31 | 2007-12-19 | Takeda San Diego, Inc. | Hydroxysteroid dehydrogenase inhibitors |
EP1908751A1 (en) * | 2006-10-03 | 2008-04-09 | EOS S.p.A. | N-hydroxy benzamides with antitumour activity |
US8796330B2 (en) | 2006-12-19 | 2014-08-05 | Methylgene Inc. | Inhibitors of histone deacetylase and prodrugs thereof |
CN106699635B (zh) * | 2015-11-12 | 2019-10-22 | 北京福元医药股份有限公司 | 一种制备Delamanid中间体的方法 |
AU2019352741A1 (en) | 2018-10-04 | 2021-05-06 | Assistance Publique-Hôpitaux De Paris (Aphp) | EGFR inhibitors for treating keratodermas |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE230399T1 (de) * | 1996-08-14 | 2003-01-15 | Astrazeneca Ab | Substituierte pyrimidinderivate und ihre pharmazeutische anwendung |
PL335732A1 (en) * | 1997-03-04 | 2000-05-08 | Monsanto Co | Sulphonyl hydroxamic acids with bivalent aryl or heteroaryl ring |
BR9916536A (pt) * | 1998-12-23 | 2002-01-02 | Searle & Co | Método para o tratamento ou prevenção de um distúrbio de neoplasia em um mamìfero em necessidade deste tratamento ou prevenção, e, combinação |
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2000
- 2000-05-12 AR ARP000102311A patent/AR035624A1/es unknown
- 2000-05-12 MX MXPA01011481A patent/MXPA01011481A/es not_active Application Discontinuation
- 2000-05-12 NZ NZ515197A patent/NZ515197A/xx unknown
- 2000-05-12 EP EP00931910A patent/EP1177173A1/en not_active Withdrawn
- 2000-05-12 AU AU49718/00A patent/AU781339B2/en not_active Ceased
- 2000-05-12 KR KR1020017014418A patent/KR20020009610A/ko not_active Application Discontinuation
- 2000-05-12 CA CA002373500A patent/CA2373500A1/en not_active Abandoned
- 2000-05-12 WO PCT/US2000/006713 patent/WO2000069819A1/en not_active Application Discontinuation
- 2000-05-12 BR BR0011291-7A patent/BR0011291A/pt not_active IP Right Cessation
- 2000-05-12 JP JP2000618236A patent/JP2002544257A/ja active Pending
- 2000-05-12 CN CN00809958A patent/CN1360577A/zh active Pending
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100621480B1 (ko) * | 2005-03-16 | 2006-09-19 | 최우혁 | 쇄미 선별 제거장치 |
Also Published As
Publication number | Publication date |
---|---|
ZA200109007B (en) | 2003-01-31 |
CN1360577A (zh) | 2002-07-24 |
AU781339B2 (en) | 2005-05-19 |
BR0011291A (pt) | 2002-05-14 |
AU4971800A (en) | 2000-12-05 |
EP1177173A1 (en) | 2002-02-06 |
NZ515197A (en) | 2004-03-26 |
CA2373500A1 (en) | 2000-11-23 |
JP2002544257A (ja) | 2002-12-24 |
WO2000069819A1 (en) | 2000-11-23 |
HK1045501A1 (zh) | 2002-11-29 |
MXPA01011481A (es) | 2005-06-20 |
AR035624A1 (es) | 2004-06-23 |
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