KR20000024484A - Antifungal composition and method to be fumigated with heating - Google Patents

Abstract

PURPOSE: Provided is a composition of heating-volatile sterilizer containing up to one compound selected from lemongrass oil, time oil or rosemary oil, which sterilizes bacteria, fungi, virus, etc by volatilizing into air, prevents the propagation of respiratory diseases, allergy or contagious diseases, and removes an offensive odor. CONSTITUTION: A composition contains one more component being 10-80 wt%, which is selected from the group consisting of lemongrass oil, time oil and rosemary oil. Peppermint oil is optionally added to the composition to improve fragrance. A composition is comprised a mat made of cotton or pulp and heated on a hot plate then volatilized into the air.

Description

Sterilizer composition and sterilization method for heating volatilization {ANTIFUNGAL COMPOSITION AND METHOD TO BE FUMIGATED WITH HEATING}

The present invention relates to a sterilizing agent composition for heating volatilization and sterilization method which easily sterilizes bacteria, fungi, viruses and the like which live in the air. More specifically, the present invention relates to a sterilizing agent composition for heating volatilization and sterilizing method which can sterilize various pathogens easily by heating a substance having sterilized ingredients deposited therein and quickly and easily volatilizing the sterilizing active ingredient into the air.

Air is the most important of the necessary conditions upon which humanity depends. Clean air is beneficial to human survival and health. Polluted air not only interferes with human growth and health but also causes various diseases. There are many microorganisms in the air and they cause the disease to move and cause decay.In particular, there are many contaminants in the emergency room and the hospital room during rainy season, large population fluidity, and influenza virus in the air during the season. Contagion is also a problem.

Preventing cross-infection by contaminants in the air to prevent disease infection and to prevent corruption has been a concern of many people as well as in medicine.

Conventional air disinfection has mainly used ultraviolet rays, various disinfectants or steam disinfection methods, but such methods not only have a bad effect on the control lungs and the human body, but also have disadvantages that must be performed in the absence of a person. In light of this, the effectiveness and continuity of the use is less effective and brings much inconvenience to life. In addition, there is an aerosol spray type disinfectant, but it is impossible to apply the entire range of space, and the discomfort and effects due to the solvent are also reduced.

The present invention, unlike the conventional method, by simply volatilizing a substance having a sterilization effect directly into the air to sterilize bacteria, fungi, viruses, etc., thereby preventing respiratory diseases, allergies, and transmission of infectious diseases, and incidentally removing indoor odors. The purpose.

The present invention is characterized by providing an air sterilizing composition containing 10-80% by weight of at least one component selected from the group consisting of lemongrass, thyme oil and rosemani oil.

In addition, the present invention is characterized in that it provides a sterilization method for sterilizing the bacteria, fungi, viruses, etc. in the air by heating and volatilizing the sterilizing composition as described above.

Natural bactericidal substances used in the present invention include extracts such as lemongrass oil, thyme oil, peppermint oil, and rosemary oil, and these ingredients are safe for the human body because they are natural products. It was found to be a bactericidal substance against bacteria, fungi and viruses. In particular, lemongrass oil, thyme oil, and rosemary oil showed high bactericidal activity against all bacteria. Peppermint oil, although its own bactericidal power, was added as an aromatic ingredient in the present invention rather than for its bactericidal effect.

The bactericidal composition of the present invention is preferably used in an amount of 10-80% by weight. If less than 10% by weight, the bactericidal power is lowered, if more than 80% by weight has a disadvantage in that the formulation.

The bactericidal composition of the present invention may volatilize the active ingredient into the air in the following manner.

First, there is a method of immersing the sterilizing composition of the present invention on a mat made of a material such as pulp or cotton and heating it on a hot plate, and second, a method of inserting a wick into a bottle containing the stock solution of the sterilizing composition of the present invention and heating it to volatilize it. .

The natural bactericidal composition volatilized in the above manner not only suppresses the growth of bacteria, fungal viruses, etc., but also suppresses the germination of mold spores that float in air to spread the disease.

First, it was carried out as follows to test the bactericidal effect of the bactericidal composition of the present invention. Isolation of bacteria in the air was carried out in the following manner. Remove the agar strip from the air sampler, incubate in the incubator for a period of time, and isolate the bacteria from the formed colonies and incubate purely. Fungi among the cultured bacteria are identified by observing the morphological characteristics on the medium and the morphology of the spores and mycelium on the microscope, and the bacteria using the Vitek system.

As a result, contaminants in the air are was identified that fungi capable of floating in the most air to the spore state, such as the kind as is black mold (Aspergillus sp), blue mold (Penicillium sp.), Fusarium (Fusarium sp.) or has been, the bacteria Staphylococcus aureus (Staphylococcus aureus), Pseudomonas aeruginosa (Pseudomonas aeruginosa) is turned out part. Since the spores of black and blue mold consist of one cell, they are easily suspended in the air, which is a major source of air pollution, and also acts as a carrier for disease transmission.

The test method was carried out as follows.

Spores of black mold and blue mold, which make up most of the air-contaminating bacteria, are selected as test bacteria, suspensions are made, and they are incubated on potato media. After forming a large amount of spores on the medium, the medium is made into pieces of uniform size in order to spread the amount of spores evenly in the air of a three-pyeong room with a constant temperature and humidity air conditioner. In addition, if a piece of medium is placed in front of the tuyeres of a constant temperature / humidity air conditioner, many spores are evenly dispersed in the air.

Subsequently, the mixed component of the present sterilizing composition was filled into a mat composed of 2.3 mm thick cotton and pulp and volatilized on a steam heating plate of 160 ± 10 ° C., and isoparaffin having a low smell of the solvent itself for proper control of volatilization. A series of kerosene was used.

Example

Hereinafter, the present invention will be described in detail based on Examples and Comparative Examples, but the technical scope of the present invention is not limited thereto.

Example 1

In 100 g of sterilized stock solution

Lemongrass Oil 16g

16 g of thyme oil

Rosemary Oil 16g

Peppermint 10g

Isfa h (42g)

The sterilized mat was prepared by mixing the sterilized stock solution with 150 milligrams of charge to about 1 gram of mat.

Example 2

In 100 g of sterilized stock solution

Lemongrass Oil 24g

Rosemary Oil 24g

Peppermint 10g

Isfa h (42g)

The sterilized mat was prepared by mixing the sterilized stock solution with 150 milligrams of charge to about 1 gram of mat.

Example 3

In 100 g of sterilized stock solution

Thyme Oil 24g

Rosemary Oil 24g

Peppermint 10g

Isfa h (42g)

The sterilized mat was prepared by mixing the sterilized stock solution with 150 milligrams of charge to about 1 gram of mat.

Example 4

In 100 g of sterilized stock solution

Lemongrass Oil 24g

Thyme Oil 24g

Peppermint 10g

Isfa h (42g)

The sterilized mat was prepared by mixing the sterilized stock solution with 150 milligrams of charge to about 1 gram of mat.

Comparative Example 1

Install a UV sterilizer on the wall of the room so that the UV rays can be evenly distributed.

Comparative Example 2

Commercially available aerosol spray sterilizers are applied in the air.

Experimental Example

The experiment was conducted in a room of about 5 pyeong, and ventilation through visits was prohibited during the experiment. The mat prepared in Example was put on the heating plate of the insecticide-type fumigator and volatilized. In the ultraviolet disinfection of Comparative Example 1, a germicidal UV lamp having a wavelength of 253.7 nanometers (nm), which is widely used in a general hospital, was placed on the room wall. It carried out by sticking and irradiating. And the aerosol spray of Comparative Example 2 sprayed 1/5 (50 grams) of the product weight. The sterilization power for each treatment was measured every 30 minutes, 60 minutes and 120 minutes, and the method for measuring the sterilization power for each treatment was collected by operating the agar strip in the air sampler in the same manner as the fungal separation method. Placing a piece of media in front of the tuyeres of a constant temperature and humidity conditioner with a strong wind causes many spores to be distributed evenly in the air.

The initial bacterial counts of each treatment group were collected by spinning spores formed on the media pieces in the room and then operating an air sampler with an agar strip inserted therein.

The sterilization test of the Examples and Comparative Examples was repeated three times, the sterilization rate was calculated by the following formula.

`` Sterilization rate (%) = Number of bacteria before disinfection-Number of bacteria after disinfection / Number of bacteria before disinfection × 100 ''

The sterilization rate was calculated as the average value of each repetition and the results are shown in Table 1 below.

Hourly sterilization rate for Examples and Comparative Examples Example 1 Example 2 Example 3 Example 4 Comparative Example 1 Comparative Example 2 30 minutes 56% 48% 44% 50% 62% 62% 60 minutes 78% 69% 67% 73% 68% 59% 120 minutes passed 85% 74% 70% 76% 74% 60%

As shown in Table 1, the sterilizing power in the air by volatilization of the natural sterilizing component used in the present invention showed a higher sterilizing effect when lemongrass oil, thyme oil, and rosemary oil were mixed and applied. The sterilization effect was slower than the ultraviolet disinfection method (Comparative Example 1) and the aerosol spray method (Comparative Example 2), but the overall disinfection was excellent. In addition, UV disinfection is an inconvenience to avoid the spot due to the danger of sterilization, and aerosol spray is a problem of discomfort caused by a large amount of solvent, with the inconvenience of spraying more than half of the can to sterilize the entire space. However, the present invention was very effective because it has a characteristic of aroma as a simple sterilization method.

As described above, the present invention, unlike the existing methods for sterilizing harmful bacteria in the air, has no risk and is simple and very effective.

Claims (5)

A composition for heating volatilization sterilization comprising 10 to 80% by weight of at least one component selected from lemongrass oil, thyme oil, rosemary oil. The air sterilizing composition of claim 1, further comprising peppermint oil to further improve the fragrance effect. A method for sterilizing airborne bacteria, fungi, viruses, and the like, comprising heating and volatilizing a sterilization composition comprising at least one component selected from lemongrass oil, thyme oil and rosemary oil. 4. The method of claim 3 wherein the heated volatilization comprises heating the volatilized heat plate on a hot plate by incorporating the composition of claim 1 into a mat comprised of a material such as pulp or cotton. 4. The method according to claim 3, wherein the heated volatilization is carried out by placing the composition of claim 1 in a container in a liquid state, inserting a wick, and heating the volatilized product.