KR102762920B1 - 바이오마커 - Google Patents

바이오마커 Download PDF

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KR102762920B1
KR102762920B1 KR1020207012372A KR20207012372A KR102762920B1 KR 102762920 B1 KR102762920 B1 KR 102762920B1 KR 1020207012372 A KR1020207012372 A KR 1020207012372A KR 20207012372 A KR20207012372 A KR 20207012372A KR 102762920 B1 KR102762920 B1 KR 102762920B1
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chromosome
interactions
chromosomal
dna
delete delete
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KR20200058527A (ko
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알렉상드르 아쿨리츠체프
어로울 셀밤 라마다스
이완 헌터
매튜 솔터
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옥스포드 바이오다이나믹스 피엘씨
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020207012372A 2017-10-02 2018-10-01 바이오마커 Active KR102762920B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762566756P 2017-10-02 2017-10-02
US62/566,756 2017-10-02
PCT/GB2018/052808 WO2019069067A1 (en) 2017-10-02 2018-10-01 BIOMARKER

Publications (2)

Publication Number Publication Date
KR20200058527A KR20200058527A (ko) 2020-05-27
KR102762920B1 true KR102762920B1 (ko) 2025-02-04

Family

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Family Applications (1)

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KR1020207012372A Active KR102762920B1 (ko) 2017-10-02 2018-10-01 바이오마커

Country Status (11)

Country Link
US (1) US12006547B2 (https=)
EP (1) EP3692168A1 (https=)
JP (2) JP2020537514A (https=)
KR (1) KR102762920B1 (https=)
CN (1) CN111344415B (https=)
AU (1) AU2018344573B2 (https=)
CA (1) CA3076450A1 (https=)
MY (1) MY200184A (https=)
SG (1) SG11202002503TA (https=)
WO (1) WO2019069067A1 (https=)
ZA (1) ZA202001821B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI884984B (zh) * 2019-09-11 2025-06-01 英商牛津生物力學公眾有限公司 診斷染色體標記
GB202016176D0 (en) * 2020-10-12 2020-11-25 Oxford BioDynamics PLC Disease marker
JP2024504062A (ja) * 2021-01-07 2024-01-30 オックスフォード バイオダイナミックス ピーエルシー 染色体相互作用
CN117203350A (zh) * 2021-01-07 2023-12-08 牛津生物动力公共有限公司 染色体相互作用
CN113035298B (zh) * 2021-04-02 2023-06-20 南京信息工程大学 递归生成大阶数行限制覆盖阵列的药物临床试验设计方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009147386A1 (en) 2008-06-02 2009-12-10 Oxford Biodynamics Limited Methods of detecting long range chromosomal interactions
WO2016207653A1 (en) * 2015-06-24 2016-12-29 Oxford Biodynamics Limited Detection of chromosome interactions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2116280A1 (en) * 1993-03-05 1994-09-06 Marcy E. Macdonald Huntingtin dna, protein and uses thereof
AU2006264564B2 (en) * 2005-07-04 2012-04-19 Erasmus University Medical Center Chromosome conformation capture-on-chip (4c) assay
JP5503942B2 (ja) * 2009-10-30 2014-05-28 シスメックス株式会社 疾患の罹患の判定方法
US8663919B2 (en) * 2011-05-18 2014-03-04 Life Technologies Corporation Chromosome conformation analysis
WO2017001568A1 (en) 2015-07-01 2017-01-05 Universitat De Lleida Treatment and prevention of amyotrophic lateral sclerosis
WO2018115802A1 (en) 2016-12-23 2018-06-28 Oxford Biodynamics Limited Typing method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009147386A1 (en) 2008-06-02 2009-12-10 Oxford Biodynamics Limited Methods of detecting long range chromosomal interactions
WO2016207653A1 (en) * 2015-06-24 2016-12-29 Oxford Biodynamics Limited Detection of chromosome interactions
WO2016207647A1 (en) 2015-06-24 2016-12-29 Oxford Biodynamics Limited Epigenetic chromosome interactions

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Biomarkers in Medicine (2010) 4(4):611-629
EBioMedicine (2017.6.23) 33:169-184
EBioMedicine (2018) 33:6-7
Journal of the Neurological Sciences (2017.10.15) 381:561-756
Nature (2016.1.7) 529:110-114
Scientific Reports (2017.5.19) 7:2186

Also Published As

Publication number Publication date
ZA202001821B (en) 2022-10-26
MY200184A (en) 2023-12-12
JP2023182591A (ja) 2023-12-26
AU2018344573A1 (en) 2020-04-09
JP2020537514A (ja) 2020-12-24
CN111344415B (zh) 2024-04-30
CA3076450A1 (en) 2019-04-11
SG11202002503TA (en) 2020-04-29
NZ762713A (en) 2025-03-28
WO2019069067A1 (en) 2019-04-11
EP3692168A1 (en) 2020-08-12
KR20200058527A (ko) 2020-05-27
JP7701419B2 (ja) 2025-07-01
US12006547B2 (en) 2024-06-11
AU2018344573B2 (en) 2020-09-17
CN111344415A (zh) 2020-06-26
US20200407790A1 (en) 2020-12-31

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