KR102758180B1 - 합성 가이드 분자, 그와 관련된 조성물 및 방법 - Google Patents

합성 가이드 분자, 그와 관련된 조성물 및 방법 Download PDF

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KR102758180B1
KR102758180B1 KR1020237043357A KR20237043357A KR102758180B1 KR 102758180 B1 KR102758180 B1 KR 102758180B1 KR 1020237043357 A KR1020237043357 A KR 1020237043357A KR 20237043357 A KR20237043357 A KR 20237043357A KR 102758180 B1 KR102758180 B1 KR 102758180B1
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guide molecule
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KR20230175330A (ko
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짐 하일
스테파니 킹
샘 사코마노
스테이시 케이프하트
세실리아 페르난데스
하리하란 자야람
브루스 이튼
카린 젬스키 베리
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에디타스 메디신, 인코포레이티드
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C12N2310/00—Structure or type of the nucleic acid
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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  • Enzymes And Modification Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020237043357A 2016-12-30 2017-12-29 합성 가이드 분자, 그와 관련된 조성물 및 방법 Active KR102758180B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662441046P 2016-12-30 2016-12-30
US62/441,046 2016-12-30
US201762492001P 2017-04-28 2017-04-28
US62/492,001 2017-04-28
KR1020197022278A KR102618864B1 (ko) 2016-12-30 2017-12-29 합성 가이드 분자, 그와 관련된 조성물 및 방법
PCT/US2017/069019 WO2018126176A1 (en) 2016-12-30 2017-12-29 Synthetic guide molecules, compositions and methods relating thereto

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KR1020197022278A Division KR102618864B1 (ko) 2016-12-30 2017-12-29 합성 가이드 분자, 그와 관련된 조성물 및 방법

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KR20230175330A KR20230175330A (ko) 2023-12-29
KR102758180B1 true KR102758180B1 (ko) 2025-01-23

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KR1020197022278A Active KR102618864B1 (ko) 2016-12-30 2017-12-29 합성 가이드 분자, 그와 관련된 조성물 및 방법

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US (1) US20230111575A1 (https=)
EP (1) EP3565895A1 (https=)
JP (3) JP7167029B2 (https=)
KR (2) KR102758180B1 (https=)
CN (2) CN118345072A (https=)
AU (2) AU2017388753A1 (https=)
CA (1) CA3048434A1 (https=)
MX (1) MX420023B (https=)
WO (1) WO2018126176A1 (https=)

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JP2025016776A (ja) 2025-02-04
AU2024205204A1 (en) 2024-09-05
MX420023B (es) 2025-01-14
JP2022173349A (ja) 2022-11-18
JP2020503049A (ja) 2020-01-30
US20230111575A1 (en) 2023-04-13
WO2018126176A1 (en) 2018-07-05
JP7610559B2 (ja) 2025-01-08
MX2019007750A (es) 2019-10-15
EP3565895A1 (en) 2019-11-13
KR20230175330A (ko) 2023-12-29
CN110249052B (zh) 2024-04-12
CN118345072A (zh) 2024-07-16
KR102618864B1 (ko) 2024-01-02
AU2017388753A1 (en) 2019-07-11
KR20190110554A (ko) 2019-09-30
JP7167029B2 (ja) 2022-11-08
CN110249052A (zh) 2019-09-17
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