KR102641141B1 - Antiviral egg carriers with biodegradability - Google Patents

Abstract

The present invention relates to biodegradable egg eggs with antiviral properties.
The present invention consists of a bottom plate with one or more concave egg seat grooves arranged to accommodate eggs, a detachable lid that covers the entire egg seat groove of the bottom plate, or an integrated lid that is connected to the bottom plate and covers the entire egg seat groove of the bottom plate. In the egg egg tray, the bottom plate or the bottom plate and the lid are made of a biodegradable polymer resin made of polylactic acid-based polymer; or a composite degradable polymer resin composed of a biodegradable resin and a petrochemical resin; a biodegradable sheet manufactured by dispersing an inorganic antiviral agent alone or two or more types of aggregated composite particles in a raw material resin selected from the group consisting of a particle size of 100 to 900 nm. Accordingly, egg eggs that implement excellent antiviral performance can be provided.

Description

ANTIVIRAL EGG CARRIERS WITH BIODEGRADABILITY}

The present invention relates to a biodegradable egg seat with antiviral performance, and more specifically, to a bottom plate with one or more concave egg seat grooves arranged to accommodate eggs, and a bottom plate that covers the entire egg seat groove of the bottom plate. In the egg egg tray consisting of a detachable lid or an integrated lid connected to the bottom plate and covering the entire egg seat groove of the bottom plate, the bottom plate or the bottom plate and the lid include a biodegradable polymer resin made of a polylactic acid-based polymer; or a composite degradable polymer resin composed of a biodegradable resin and a petrochemical resin; a biodegradable sheet manufactured by dispersing an inorganic antiviral agent alone or two or more types of aggregated composite particles in a raw material resin selected from the group consisting of a biodegradable resin and a petrochemical resin with a particle size of 100 to 900 nm. This relates to biodegradable egg eggs with excellent antiviral performance.

In general, eggs are the most easily consumed protein source and provide various nutrients such as riboflavin (vitamin B2), vitamin B12, biotin (B7), pantothenic acid (B5), iodine, and selenium, as well as choline, supporting muscle and bone health. It is a food ingredient that is used in the diet of all generations, including infants, toddlers, and growing children, as it helps with brain development.

Due to these advantages, eggs are sold in small packages for snacks at convenience stores, etc., to those sold in packs of 10 or more at home, and their materials range from transparent to opaque.

A typical egg carton is a type that holds eggs by molding thick paper or press-molding paper pulp. It is formed with concave and convex parts that can accommodate eggs. Eggs are stored in these concave parts and The stored egg is supported by the convex portions formed around all four sides of the portion. However, in the above method, when a large number of egg cartons containing eggs are loaded, the concave part of the egg carton at the top is located on the convex part of the egg carton at the bottom, and the eggs are exposed to the outside. When loading or transporting a large amount of egg cartons, there is a problem that the eggs are easily damaged due to impact.

However, egg cartons manufactured by dissociating pulp using the above-mentioned paper or pulp mold have disadvantages in that their strength decreases when exposed to moisture, mold easily inhabits them, and in the case of recycled pulp, there is a possibility of containing fluorescent substances.

In particular, in the case of egg cartons manufactured by dissociating the pulp, there is a problem that once the paper or pulp is contaminated with bacteria, etc., it is very difficult to sterilize it.

According to Non-Patent Document 1, when office paper was infected with various types of bacteria, an experiment was conducted to see how long it survived, and as a result, it survived stably on the paper for more than 72 hours, and although the probability was low, it could be transferred from human hands to paper or from paper back to humans. It is reported that it is delivered by hand. In particular, they point out that unlike other materials, once paper is infected, it is difficult to remove it with chemical agents.

Additionally, eggshells have a cuticle membrane, which plays a role in preventing bacterial invasion. However, washing eggs causes another problem in that the cuticle membrane is removed or damaged, making it easier for bacteria to penetrate. In other words, the pores in the eggshell are 10 to 30㎛ in size, and with a hole of this size, bacteria and smaller viruses can easily penetrate and infect the egg.

To solve this problem, a method of using an egg carton in which the egg seat groove and the lid are formed integrally with a synthetic resin material (polystyrene foam sheet, non-foam transparent sheet, non-foam PP sheet, etc.) is being used.

However, this still does not solve the problem that eggs are easily broken due to the thin thickness of the synthetic resin, and it does not rot easily, which is a major cause of environmental pollution, raising another problem. In other words, most of the existing synthetic resin egg nests are not eco-friendly products, and especially if they are made using recycled resin, the possibility of contamination of foreign substances such as heavy metals cannot be completely eliminated.

Since the 2000s, due to the outbreak of epidemic diseases such as SARS and new flu, interest in harmful microorganisms to prevent bacterial and viral infections has increased, and continuous research has been conducted.

In particular, in a situation where the spread of coronavirus (COVID-19) infection is not slowing down, there is a need for research on virus vaccines and the development of products with antiviral performance as well as daily quarantine due to the nature of the virus being transmitted through contact.

Among them, if antiviral properties are given to egg eggs, concerns about viruses can be eliminated or minimized while packaging eggs in the conventional manner, so it is hygienic and does not incur additional costs in the packaging process, and ultimately, stable distribution without a decrease in egg consumption can be achieved. As it continues, it will be helpful not only for people's lives but also for poultry farms.

In general, microorganisms are living organisms that always exist around us. Although there are beneficial microorganisms that help humans, some pathogenic microorganisms, such as bacteria, harmful molds, and viruses, cause food spoilage, cause disease, and produce bad odors. It causes harm to the human body.

The possibility of the existence of viruses was already suggested in the late 19th century, but the existence of viruses was confirmed in the 1930s because viruses are extremely small. In general, the average size of human cells is about 20 to 100㎛, while bacteria are smaller at 1 to 10㎛. Although the minimum size that can be distinguished with the naked eye varies from person to person, it is about 0.1 mm, so bacteria cannot be seen with the naked eye, but the presence of bacteria can be sufficiently confirmed using an optical microscope.

However, since the average size of viruses is much smaller, about 10 to 300 nm, they cannot be observed using an optical microscope with a maximum magnification of only 1,000 times. Therefore, the existence of viruses became possible after the development of electron microscopes with much larger magnifications (maximum magnification of 1 million times).

A virus is an entity that has the characteristics of both living and non-living things. It is basically a simple structure containing nucleic acid (DNA or RNA), the genetic material, inside an envelope made of protein.

Therefore, unlike bacteria, viruses cannot metabolize on their own and therefore cannot perform vital activities. However, when they enter a host cell, they parasitize the host cell's vital activity process and replicate their genetic material and protein coat to proliferate. I order it.

When viruses that exist in the form of protein crystals encounter a host cell, they bind to the cell membrane of the host cell and then enter the inside. The virus that enters the host cell uses the host cell's genetic material replication and protein production functions to create its own genetic material and protein envelope, then reassembles them to proliferate virus cells that resemble itself.

Recently, the number of outbreaks caused by various viruses such as SARS, bird flu, and mass food poisoning has increased rapidly, and the spread of coronavirus (COVID-19) infection is urgently needed in the market for personal or disposable products with antiviral properties. .

Patent Document 1 is an invention regarding silver nano antibacterial plastic pellets, which are made by mixing colloidal silver nano with pellet-shaped plastic raw materials (PE, PP, PVC, ABS, AS, PS, etc.) at a certain ratio to form a pellet. After molding the masterbatch, when the product (for example, plastic film, sheet, molded product, etc.) is remolded by mixing the masterbatch with the raw materials of the plastic product in a certain ratio by using the silver nano coating layer formed on the surface of the masterbatch. , it is disclosed that it exerts an antibacterial effect on the surface and material of plastic products.

However, in conventional inventions, the efficacy of antibacterial and antiviral substances is proposed by mixing them without distinction. In particular, in the case of the above invention, a method of manufacturing colloidal silver nano in the form of a pellet, putting them together, molding them, and coating the surface of the pellet with silver is disclosed. However, the particle size of the colloidal state is about 20 to 50 nm.

On the other hand, according to Non-Patent Document 2, the threatening effects of silver ions or silver nanoparticles on the environment and human health are reported. Silver nanoparticles are useful as antibacterial substances, but in the case of silver nanoparticles at the 5 to 50 nm level, cell Toxicity is reported.

Based on these reports, safety issues have been raised about the nano-sized silver nanoparticles because they can pass through the skin gap (75 nm) and reach organs when applied to the human body, and in fact, European (Scientific Committee on Emerging and Newly Identified) Health Risks defines materials smaller than 100 nm as nanomaterials, and considering their toxicity to the human body, the use of particles with at least 50% of particles larger than 100 nm is regulated.

Non-patent paper 3 states that coronaviruses survive on various surfaces for tens of hours to 7 days, and that cleaning with traditional disinfection returns to the state before cleaning within 2.5 hours, so it is only a temporary alternative. Therefore, in order to combat the attachment, colonization, and subsequent proliferation of viruses, we introduce research on active surfaces and propose surfaces that are resistant to infection through natural coatings, artificial coatings, or biomimetic coatings. With this approach, despite the debate about the cytotoxicity and biocompatibility of nanoparticles for human cells, nano-particles including silver, gold, copper, zinc oxide, titanium dioxide and bionanoparticles such as carbon-based nanotubes and chitosan have been used. It is expected that the use of particles will be effective by significantly increasing the contact area with microorganisms caused by viruses at the size of 1 to 10 nm.

Accordingly, as a result of a thorough review of the existing problems and necessities, the present inventors found a bottom plate with one or more concave egg seat grooves arranged to accommodate eggs, and a detachable lid that covers the entire egg egg seat groove of the bottom plate or is connected to the bottom plate. In the egg nest consisting of an integrated lid that covers the entire egg seat groove of the bottom plate, the bottom plate or the bottom plate and the lid are made of a biodegradable polymer resin made of a polylactic acid-based polymer; or a composite degradable polymer resin composed of a biodegradable resin and a petrochemical resin; a biodegradable sheet manufactured by dispersing an inorganic antiviral agent alone or two or more types of aggregated composite particles in a raw material resin selected from the group consisting of a particle size of 100 to 900 nm. By providing an egg egg, the particle size of the inorganic antiviral agent is controlled to prevent skin penetration, and at the same time, the inorganic antiviral agent inactivates the virus before entering the human body upon contact with an external virus or prevents RNA from replicating even if infected. By confirming the implementation of antiviral performance by inhibiting the present invention, the present invention was completed.

Republic of Korea Patent No. 0854730 (announced on August 27, 2008)

“Survival of Bacterial Pathogens on Paper and Bacterial Retrieval from Paper to Hands: Preliminary Results.” , Am. J Nurs., 2011, 111(12), 30-34. “Silver or silver nanoparticles: a hazardous threat to the environment and human health”, J. Appl. Biomed., 2008, 6, 117-129. “A critical evaluation of current protocols for self-sterilizing surfaces designed to reduce viral nosocomial infections”, Am. J. Infect. Control, 2020, 48, P1255-1260.

The purpose of the present invention is to provide biodegradable egg eggs with antiviral properties.

In order to achieve the above object, the present invention provides a base plate with one or more concave egg seat grooves arranged to accommodate eggs, a detachable lid that covers the entire egg seat groove of the bottom plate, or an egg egg seat groove on the bottom plate that is connected to the bottom plate. In the egg nanjja consisting of an integrated lid that covers the entire thing,

A biodegradable polymer resin in which the bottom plate or the bottom plate and lid are made of a polylactic acid-based polymer; or a composite degradable polymer resin composed of a biodegradable resin and a petrochemical resin; a biodegradable sheet prepared by dispersing an inorganic antiviral agent alone or two or more types of aggregated composite particles in a raw material resin selected from the group consisting of a particle size of 100 to 900 nm. We provide biodegradable egg eggs with antiviral properties.

The inorganic antiviral agent is selected from the group consisting of silver nanoparticle complexes, silver ion-containing nanocomposites, copper monovalent compounds, zinc oxide nanoparticles, and ferrite nanoparticles, either alone or in the form of a mixture of two or more types.

In the above, the silver nanoparticle composite or silver ion-containing nanocomposite is any one selected from the group consisting of silica (SiO ₂ ), alumina, zeolite, minerals including sericite mordenite, cristobalite, and bentonite, talc, cellulose derivatives, paraffin, and wax. It is preferable that silver nanoparticles or silver ion-containing nanoparticles are adsorbed or combined.

In the above, the ferrite nanoparticles include alpha-ferrite (α-Fe ₂ O ₃ ), zinc ferrite (ZnFe ₂ O ₄ ), manganese ferrite (MnFe ₂ O ₄ ), nickel ferrite (NiFe ₂ O ₄ ), and iron hydroxide (α -FeOOH) is a combination of one or more selected from the group consisting of

The biodegradable egg egg having antiviral performance of the present invention contains 0.1 to 60 parts by weight of an inorganic antiviral agent based on 100 parts by weight of the biodegradable or composite degradable polymer resin.

In addition, the biodegradable sheet of the present invention uses a biodegradable polymer resin made of a polylactic acid-based polymer or a composite degradable polymer resin made of a biodegradable resin and a petrochemical resin as a raw material resin. A preferred example of the biodegradable resin is Polylactic acid (PLA), polyhydroxyalkanoates (PHA), polybutylene adipate-co-terephthalate (PBAT), polybutylene succinate-adipate -co-adipate, PBSA), polybutylene succinate adipate-co-terephthalate (PBSAT), polybutylene succinate (PBS), polyvinyl alcohol, PVA), poly glycolic acid (PGA), polylactic-co-glycolic acid (PLGA) and polycaprolactone (PCL), modified starch resin and thermoplastic starch ( It is selected from the group consisting of thermoplastic starch (TPS) alone or in a mixed form of two or more types.

In the biodegradable egg egg tray with antiviral properties of the present invention, the bottom plate or the bottom plate and lid include a transparent polylactic acid (PLA) non-foam sheet; Opaque PLA non-foam sheet; Extrusion foam sheet made of PLA-based polymer; and a multilayer sheet in which at least one surface of the extruded foam sheet is laminated with a biodegradable polymer resin made of a polylactic acid polymer or a non-foamed sheet made of a petrochemical resin. The bottom plate and lid can be combined with the same sheet material or different sheet materials.

In the above, the non-foam sheet may be laminated to the inner surface of the bottom plate made of extruded foam sheet or the outer surface of the bottom plate.

At this time, the non-foam sheet preferably contains 0.1 to 60 parts by weight of an inorganic antiviral agent based on 100 parts by weight of biodegradable polymer resin or petrochemical resin, and the thickness of the non-foam sheet is 50 to 500 μm.

In addition, the biodegradable egg egg tray with antiviral properties of the present invention includes a bottom plate or bottom plate and a transparent polylactic acid (PLA) non-foam sheet; Opaque PLA non-foam sheet; Extrusion foam sheet made of PLA-based polymer; And on at least one side of the extruded foam sheet, a multilayer sheet in which a non-foam sheet made of a biodegradable polymer resin made of polylactic acid polymer or a petrochemical resin is laminated,

It may include a form in which an inorganic antiviral active layer is formed by applying an active layer solution containing a single or mixed form selected from inorganic antiviral agents and dispersants.

The inorganic antiviral active layer is formed by a coating method or a spray method using a mist nozzle, and is characterized in that the inorganic antiviral agent is dispersed and coated at 0.01 to 5 g/m2.

In the biodegradable egg nest with antiviral properties of the present invention, the dispersing agent is one selected from the group consisting of polyethylene glycol (PEG), citric acid, lactic acid, and polylactic acid (PLA).

The biodegradable egg egg with the above antiviral performance has excellent antiviral properties against one or more selected from the group consisting of filamentous coronavirus (fCoV), influenza A virus (FluA), avian influenza (AI) virus, and porcine virus. Implement.

Furthermore, the present invention provides, based on 100 parts by weight of the organic solvent, 0.1 to 20 parts by weight of an inorganic antiviral agent and 0.1 to 0.1 to 20 parts by weight of a dispersing agent selected from the group consisting of polyethylene glycol (PEG), citric acid, lactic acid and polylactic acid (PLA), alone or in mixed form. Provided is a coating composition having antiviral performance containing 20 parts by weight.

The inorganic antiviral agent is selected from the group consisting of silver nanoparticle complexes, silver ion-containing nanocomposites, copper monovalent compounds, zinc oxide nanoparticles, and ferrite nanoparticles, either alone or in a mixed form of two or more types, wherein the silver nanoparticle complex or silver ion The nanocomposite contains silver nanoparticles or silver ion-containing nanoparticles selected from the group consisting of minerals including silica (SiO ₂ ), alumina, zeolite, mordenite, cristobalite, and bentonite, talc, cellulose derivatives, paraffin, and wax. adsorbed or bound.

In the above, the ferrite nanoparticles include alpha-ferrite (α-Fe ₂ O ₃ ), zinc ferrite (ZnFe ₂ O ₄ ), manganese ferrite (MnFe ₂ O ₄ ), nickel ferrite (NiFe ₂ O ₄ ), and iron hydroxide (α -FeOOH) is a combination of one or more selected from the group consisting of

In addition, the organic solvents include tetrahydrofuran (THF), chlorinated organic solvents including chloroform, acetonitrile, dioxane, dimethylformamide (DMF), dimethylacetamide (DMAc), ethanol, methanol, normal-propyl alcohol, or isopropanol. -Alcohols selected from propyl alcohol, Chlorinated organic solvents including chloroform, benzene, toluene, acetonitrile, and dioxane are used.

According to the present invention, it is possible to provide a biodegradable egg tray with antiviral properties.

The egg egg of the present invention is a biodegradable polymer resin made of polylactic acid-based polymer; or a composite degradable polymer resin composed of a biodegradable resin and a petrochemical resin; a biodegradable sheet manufactured by dispersing an inorganic antiviral agent alone or two or more types of aggregated composite particles in a raw material resin selected from the group consisting of a particle size of 100 to 900 nm. Accordingly, the particle size control of the inorganic antiviral agent prevents skin penetration, and at the same time, the inorganic antiviral agent inactivates the virus before entering the human body by contact with the virus or inhibits RNA replication even if infected. Egg eggs with excellent antiviral performance can be provided.

The biodegradable egg egg with antiviral performance of the present invention can meet the market demand for various viruses such as SARS, avian influenza, mass food poisoning, and coronavirus (COVID-19) infection.

Figure 1 is a schematic diagram of the cross section of a biodegradable non-foaming sheet having antiviral properties for producing egg eggs of the present invention;
Figure 2 is a schematic diagram of the cross section of the biodegradable foam sheet with antiviral properties for producing egg egg nests of the present invention;
Figure 3 is a schematic diagram of the cross section of a biodegradable sheet with antiviral properties for producing egg eggs of the present invention;
Figure 4 is a schematic diagram of a cross-section of a biodegradable sheet with antiviral properties for producing egg eggs of the present invention;
Figure 5 is a cross-sectional photograph of the PLA (nZnO) biodegradable sheet containing ZnO prepared in Example 1 of the present invention;
Figure 6 is a cross-sectional photograph of the PLA (CuZn) biodegradable sheet mixed with ZnO/CuI prepared in Example 2 of the present invention;
Figure 7 is a cross-section of a PLA (AgNP) biodegradable sheet containing silver nanoparticle composite prepared in Example 3 of the present invention;
Figure 8 is a cross-section of the CuI-incorporated PLA (CuI) biodegradable sheet prepared in Example 4 of the present invention;
Figure 9 is a cross-section of a PLA (nZnAgCu) biodegradable sheet containing ZnO/silver nanoparticle composite/CuI prepared in Example 5 of the present invention;
Figure 10 is a cross-sectional schematic diagram of another embodiment of a biodegradable sheet with antiviral properties for producing egg eggs of the present invention, on which an inorganic antiviral active layer containing one type of inorganic antiviral agent is formed,
Figure 11 is a cross-sectional schematic diagram of the sheet in Figure 10 on which an inorganic antiviral active layer containing two types of inorganic antiviral agents is formed;
Figure 12 is a cross-sectional schematic diagram of another embodiment of the biodegradable sheet having antiviral properties for producing egg egg cakes of the present invention;
FIG. 13 is a cross-sectional schematic diagram of another embodiment of the biodegradable sheet with antiviral properties for producing egg yolks shown in FIG. 12.

Hereinafter, the present invention will be described in detail.

The present invention consists of a bottom plate with one or more concave egg seat grooves arranged to accommodate eggs, a detachable lid that covers the entire egg seat groove of the bottom plate, or an integrated lid that is connected to the bottom plate and covers the entire egg seat groove of the bottom plate. In the egg orchid,

A biodegradable polymer resin in which the bottom plate or the bottom plate and lid are made of a polylactic acid-based polymer; or a composite degradable polymer resin composed of a biodegradable resin and a petrochemical resin; a biodegradable sheet prepared by dispersing an inorganic antiviral agent alone or two or more types of aggregated composite particles in a raw material resin selected from the group consisting of a particle size of 100 to 900 nm. We provide biodegradable egg eggs with antiviral properties.

In the above, “biodegradable sheet” refers to a biodegradable polymer resin made of polylactic acid-based polymer; Or a composite degradable polymer resin made of biodegradable resin and petrochemical resin; including single-layer, multi-layer, non-foamed and foamed structures formed by T-dye, blown and extrusion foam using raw material resin, based on a thickness of 0.254 mm. Structures defined as sheets when the thickness is greater than the above or films when the thickness is less than the above are collectively referred to as sheets.

Specifically, in the biodegradable egg egg tray with antiviral properties of the present invention, the bottom plate or the bottom plate and lid include a transparent polylactic acid (PLA) non-foam sheet; Opaque PLA non-foam sheet; Extrusion foam sheet made of PLA-based polymer; and a multilayer sheet in which at least one surface of the extruded foam sheet is laminated with a biodegradable polymer resin made of a polylactic acid polymer or a non-foamed sheet made of a petrochemical resin. The bottom plate and lid can be combined with the same sheet material or different sheet materials.

As an example, in the form of an egg seat, a bottom plate with one or more egg seat grooves of a concave shape arranged to accommodate an egg, a separate lid that covers the entire egg seat groove of the bottom plate, or an egg egg seat groove on the bottom plate that is connected to the bottom plate. It includes a form consisting of an integrated lid that covers the whole, and can be adopted without being limited to the form of a conventional egg packaging container.

At this time, the bottom plate and lid may be made of a transparent PLA non-foaming sheet.

In addition, when the lid is a transparent PLA non-foam sheet, the bottom plate is an opaque PLA non-foam sheet; Extrusion foam sheet made of PLA-based polymer; or a multilayer sheet in which a non-foam sheet made of a biodegradable polymer resin made of a polylactic acid-based polymer or a petrochemical resin is laminated on at least one side of the extruded foam sheet; can be selected from among.

As another example, the bottom plate and lid may be made of an extruded foam sheet made of PLA-based polymer.

Additionally, the bottom plate and lid may be made of a multi-layer sheet in which a non-foam sheet made of a biodegradable polymer resin made of a polylactic acid polymer or a petrochemical resin is laminated to at least one side of the extruded foam sheet.

At this time, the non-foam sheet may be laminated to the inner surface of the bottom plate made of extruded foam sheet or the outer surface of the bottom plate.

In the above, lamination is not limited to means such as coating, application, or co-extrusion, but means forming a multi-layer structure using these methods.

The biodegradable egg egg tray with antiviral performance of the present invention is made by mixing 0.1 to 60 parts by weight of an inorganic antiviral agent on the bottom plate or the biodegradable sheet constituting the bottom plate and lid, and agglomerating the inorganic antiviral agent alone or two or more types into the biodegradable sheet. If the composite particles meet the characteristics of being dispersed in a particle size of 100 to 900 nm, the combination of biodegradable sheet materials can be changed and manufactured according to the price, thickness and strength specifications required by the market.

Figure 1 is a cross-sectional schematic diagram of a biodegradable non-foam sheet with antiviral properties for producing egg eggs of the present invention, and Figure 2 is a schematic cross-section of a biodegradable foam sheet with antiviral properties for manufacturing egg eggs of the present invention. It shows the shape in which an inorganic antiviral agent is incorporated into the sheet.

Figure 3 is a cross-sectional schematic diagram of a biodegradable sheet with antiviral properties for producing egg eggs of the present invention, wherein at least one surface of the biodegradable foam base sheet (11) is coated with a polylactic acid-based polymer and an inorganic antiviral agent composition (31). This distributed The non-foaming sheet 30 is laminated.

FIG. 4 is a schematic diagram showing a cross section of a biodegradable sheet further containing an inorganic antiviral agent (21) in the biodegradable foam base sheet (11) in FIG. 3.

In FIGS. 3 and 4, the non-foam sheet 30 contains 0.1 to 60 parts by weight of an inorganic antiviral agent based on 100 parts by weight of a biodegradable polymer resin or petrochemical resin made of polylactic acid polymer, providing antiviral properties. At the same time, it reinforces the strength of the entire sheet.

In addition, the non-foam sheet 30 preferably has a thickness of 50 to 500 ㎛, which may vary depending on the intended use, and the thickness and strength specifications may be changed depending on the demand of the consumer for the biodegradable sheet.

Figure 10 shows another embodiment of a biodegradable sheet with antiviral properties for producing egg eggs according to the present invention, and shows an inorganic antiviral active layer containing one type of inorganic antiviral agent (41) on at least one surface of the biodegradable foam base sheet (11). (40) is a cross-sectional schematic diagram of the sheet formed, and Figure 11 is a cross-sectional schematic diagram of the sheet on which the inorganic antiviral active layer 40 containing two types of inorganic antiviral agents (41, 42) in Figure 10 is formed.

10 and 11 illustrate the foam base sheet 11, but the present invention is not limited thereto.

Figure 12 is another embodiment of a biodegradable sheet with antiviral properties for producing egg eggs of the present invention, which consists of a biodegradable non-foaming base sheet 10 and a biodegradable polymer resin made of a polylactic acid-based polymer or a petrochemical resin. The non-foam sheet 50 is a laminated multilayer sheet, and an inorganic antiviral active layer 40 containing two types of inorganic antiviral agents 41 and 42 is formed on at least one side of the multilayer sheet.

Figure 13 illustrates a cross-sectional schematic diagram of another embodiment of the antiviral biodegradable sheet of Figure 12.

Specifically, in the antiviral biodegradable sheet of FIGS. 12 and 13, a multilayer sheet structure in which a biodegradable non-foam sheet 50 is laminated on biodegradable base sheets 10 and 11, and an inorganic antiviral active layer 40 ) is formed, and provides strength to the antiviral biodegradable sheet, and the thickness and strength specifications can be changed depending on the intended use.

The biodegradable base sheet can be changed to a non-foam base sheet 10 or a foam base sheet 11. In particular, as shown in FIG. 13, the biodegradable non-foam sheet 50 is placed on the foam base sheet 11. As the inorganic antiviral active layer 40 is formed on the laminated multilayer sheet, it can provide not only strength but also gas barrier properties, and fundamentally prevent virus penetration into the foam cells of the foam base sheet 11. .

Hereinafter, the characteristics of each composition of the biodegradable egg egg with antiviral performance of the present invention will be described in detail.

(1) Raw material resin of biodegradable sheet

The biodegradable polymer resin made of a polylactic acid-based polymer as a raw material resin can be either crystalline polylactic acid alone or a combination of crystalline polylactic acid and amorphous polylactic acid. At this time, in order to realize not only the impact resistance and in-mold molding stability of the polylactic acid resin, but also the heat resistance stability of the molded product, this can be achieved by adjusting the mixing ratio of the crystalline polylactic acid and the amorphous polylactic acid.

As another raw material resin, the material of the composite degradable polymer resin mixed with the biodegradable resin containing polylactic acid and petrochemical resin is optimized to meet the requirements for bio-based plastics in consideration of strength and productivity. Any polylactic acid-based polymer composition can be used. It is preferably composed of 60 to 99% by weight of biodegradable resin and 1 to 40% by weight of petrochemical resin. At this time, the biodegradable resin includes poly L-lactic acid (hereinafter referred to as “PLLA”) and poly D-lactic acid (hereinafter referred to as “PDLA”), but may further include known biodegradable resins. Preferred biodegradable resins include polyhydroxyalkanoates (PHA), polybutylene adipate-co-terephthalate (PBAT), and polybutylene succinate-adipate (polybutylene succinate-co- adipate, PBSA), polybutylene succinate adipate-co-terephthalate (PBSAT), polybutylene succinate (PBS), polyvinyl alcohol (PVA), poly glycolic acid (PGA), poly lactic-co-glycolic acid (PLGA) and polycaprolactone (PCL), modified starch resin and thermoplastic starch, TPS) may be further included alone or in a mixture of two or more types selected from the group consisting of

In addition, the petrochemical resin may be any one or a mixture of two or more thermoplastic resins selected from polystyrene, polyethylene, polypropylene, polyester, polycarbonate, acrylic resin, ethylene vinyl acetate resin, polyvinyl alcohol, or polyvinyl chloride. It is preferable to use, but there are no particular restrictions on the use of polymer resins other than those listed above. At this time, the petrochemical resin is contained at 1 to 40% by weight. In this case, if it is less than 1% by weight, the content of biodegradable polymer resin increases and decomposition is improved, but the improvement in heat resistance is insufficient, and the composite properties expected from mixing petrochemical resins are poor. The improvement effect is improved, but on the other hand, if the content of petrochemical resin exceeds 40% by weight, there is a problem that the carbon dioxide footprint of PLA decreases. The above composite degradable polymer resin composition is a biodegradable resin. Compared to the case where it is used alone, the biodegradation period can be shortened or, in some cases, the fastness can be improved to extend the useful life.

(2) Chain extender

Even if the polylactic acid used in the present invention is well dried, if the molecular weight is low, it lacks strength and becomes brittle, making post-processing difficult. Therefore, for the purpose of increasing the molecular weight of the polylactic acid, a chain extender is used. ) is used.

Preferred examples of chain extenders used in the present invention include diglycidyl ether series, the group consisting of terephthalate diglycidyl ether, trimethylolpropane diglycidyl ether, and 1,6-hexanediol diglycidyl ether. An epoxy-based compound selected from; Isocyanate-based compounds selected from the group consisting of hexamethylene diisocyanate, tolylene diisocyanate, xylylene diisocyanate, diphenylmethane diisocyanate, and triisocyanate; (meth)acrylic compounds; and lauroyl peroxide, benzoyl peroxide, azo-bis-isobutyl nitrile, tri-butyl hydroperoxide, dicumyl peroxide, di-tri-butyl peroxide, 2,5 dimethyl-2,5 di(thibutyl) Peroxy)hexane (2,5-Dimethyl-2,5-di(t-butyl peroxy)hexane), 1,3-bis(thi-butylperoxy-isopropyl)benzene (1,3-Bis(t- peroxide-based compounds including buthyl peroxy-isoproplybenzene); any one or more than one type selected from the group consisting of is used.

At this time, when the chain extender is used in an amount of 0.05 to 4 parts by weight, more preferably 0.1 to 2 parts by weight, based on 100 parts by weight of polylactic acid, the effect of improving heat resistance is evident. If the content of the chain extender is less than 0.05 parts by weight, the effect of increasing molecular weight is insufficient, making it difficult to manufacture into a sheet. If it exceeds 4 parts by weight, crystallinity and heat resistance are improved, but excessive increase in molecular weight and crosslinking cause As a result, there is a risk that the extruder die may become clogged, causing problems in the process.

(3) Foam nucleating agent and foaming agent

In the production of the extruded foam sheet among the biodegradable sheets of the present invention, the foam nucleating agent may be an inorganic foaming nucleating agent such as talc or silica, or an organic foaming nucleating agent such as calcium stearate. In particular, the foaming nucleating agent may be added in the form of a masterbatch. When manufacturing a masterbatch, additional dispersants, stabilizers, antioxidants, ultraviolet stabilizers, lubricants, etc. can be added to control the dispersibility of the foaming nucleating agent and improve processability. Additionally, instead of adding the dispersant together when preparing the masterbatch, a dispersant may be added separately. At this time, stearic acid amide, etc. can be used as a dispersant.

The foaming nucleating agent preferably contains 0.01 to 4 parts by weight based on 100 parts by weight of the polylactic acid-based polymer composition. In this case, if the content is too small (less than 0.01 parts by weight), the polylactic acid-based resin particles cannot be sufficiently foamed. There is no, and if it exceeds 4 parts by weight, the function of the foaming nucleating agent cannot be expected any further, and there is a risk that the expandability and fusion properties of the obtained foamed particles during molding in a mold may become insufficient.

Additionally, on the first extruder, a foaming agent is pressurized together with the polylactic acid-based resin particles and the foaming nucleating agent, and the content of the foaming agent is 1 to 30 parts by weight, preferably 3 to 20 parts by weight. At this time, the blowing agent may be selected from the group consisting of propane, isobutane, n-butane, and cyclobutane, or a mixture thereof; isopentane, n-pentane, and cyclopentane alone or in mixtures thereof; Isohexane, n-hexane, cyclohexane, trichlorofluoromethane, dichlorodifluoromethane, chlorofluoromethane, trifluoromethane, 1,1,1,2-tetrafluoroethane, 1-chloro-1 , 1-difluoroethane, 1,1-difluoroethane, 1-chloro-1,2,2,2-tetrafluoroethane, nitrogen, carbon dioxide, argon, and air. Among these, physical foaming agents that do not destroy the ozone layer and are inexpensive are preferable, and specifically, nitrogen, air, and carbon dioxide are preferable. Additionally, with respect to the amount of foaming agent used, carbon dioxide is preferable because foamed particles with a smaller apparent density can be obtained. Additionally, two or more types of blowing agents, such as carbon dioxide and isobutane, may be used in combination.

(4) Inorganic antiviral agents

The inorganic antiviral agent of the present invention is used alone or in a mixture of two or more types selected from the group consisting of silver nanoparticle complexes, silver ion-containing nanocomposites, copper monovalent compounds, zinc oxide nanoparticles, and ferrite nanoparticles.

In the case of silver nanoparticles among the inorganic antiviral agents, their activity against bacteria and viruses is known, and continuous research is ongoing. However, research results show that the activity depends on the particle size, and in the case of very small particle sizes of silver nanoparticles of 5 to 50 nm. As problems with skin penetration and toxicity were pointed out, the harmfulness of silver nanoparticles to the human body continued to increase. It is emerging [Non-patent Document 2].

Therefore, the inorganic antiviral agent of the present invention contains inorganic antivirals alone or two or more types of aggregated composite particles dispersed in a particle size of 100 to 900 nm. By controlling the particle size of the inorganic antiviral agent, skin penetration can be prevented and at the same time, excellent antiviral properties can be achieved by contact with external viruses.

As another method, the present invention uses a composite in the form of a carrier having a three-dimensional skeletal structure with fine pores as an example of supporting an antibacterial metal component. In a preferred example, silver nanoparticles or silver ion-containing nanoparticles are selected from the group consisting of silica (SiO ₂ ), minerals including alumina, zeolite, sericite, mordenite, cristobalite, and bentonite, talc, cellulose derivatives, paraffin, and wax. Adsorption to either or It is in the form of a combined complex, and may further include a known support if it can support silver nanoparticles or silver ion-containing nanoparticles.

At this time, if the particle size of the composite in the form of a carrier satisfies the particle size of 100 to 900 nm, the particle size of the silver nanoparticles or silver ion-containing nanoparticles supported on the carrier may also include a particle size of 1 to 100 nm. .

The silver ion-containing nanocomposite of the present invention is explained in the examples using silica particles in which silver ions and zinc ions are combined, but it will not be limited thereto.

As other inorganic antiviral agents used in the present invention, copper monovalent compounds are effective in achieving antiviral properties, and CuI, CuCl, Cu ₂ S, Cu ₂ O etc. desirable.

In the examples of the present invention, CuI is used as the copper monovalent compound, but there will be no particular limitation as long as it is an ionic compound combined with a copper monovalent cation and an anion capable of ionic bonding.

Another inorganic antiviral agent is zinc oxide nanoparticles, which are metal oxide particles that are harmless to the human body with strong antibacterial activity and high stability.

In an example of the present invention, more desirable antiviral performance can be confirmed when the zinc oxide nanoparticles and ferrite nanoparticles are mixed. At this time, the ferrite nanoparticles include alpha-ferrite (α-Fe ₂ O ₃ ), zinc ferrite (ZnFe ₂ O ₄ ), manganese ferrite (MnFe ₂ O ₄ ), nickel ferrite (NiFe ₂ O ₄ ), and iron hydroxide. It is a combination of at least one selected from the group consisting of (α-FeOOH).

Specifically, in the inorganic antiviral agent in the form of a mixture of zinc oxide (ZnO) nanoparticles and ferrite nanoparticles used in the examples, the ferrite nanoparticles include alpha-ferrite (α-Fe ₂ O ₃ ) and zinc ferrite (ZnFe). ₂ O ₄ ) and manganese ferrite (MnFe ₂ O ₄ ). However, two or more types of aggregated composite particles may be combined in various ways within the range that satisfies the particle size requirements.

The inorganic antiviral agent contained in the biodegradable sheet of the present invention includes a biodegradable polymer resin made of polylactic acid-based polymer; or a composite degradable polymer resin made of biodegradable resin and petrochemical resin; Based on 100 parts by weight, 0.1 to 60 parts by weight, more preferably 1 to 30 parts by weight, of an inorganic antiviral agent is included. At this time, if the inorganic antiviral agent is contained in less than 0.1 parts by weight, the expression of antiviral performance is insufficient, and if the inorganic antiviral agent is contained in excess of 60 parts by weight, not only is the economic feasibility compared to the effect, but also the polymer physical properties and processing characteristics are affected due to the excessive use of the inorganic antiviral agent. This is undesirable because it has the problem of being significantly reduced.

Through the above, the present invention prevents skin penetration by controlling the particle size of the inorganic antiviral agent by dispersing the particle size of the inorganic antiviral agent alone or two or more types of aggregated composite particles to 100 to 900 nm, and at the same time, the inorganic antiviral agent Biodegradable egg eggs with excellent antiviral performance can be provided by inactivating the virus before it enters the human body through contact with the virus or by inhibiting RNA replication even if infected.

In addition, even if the virus has once infected the human body, in the case of an RNA-type virus, the nanoparticles of the inorganic antiviral agent are adsorbed to the RNA and interfere with replication, thereby realizing antiviral performance.

(5) Non-foam sheet

Among the biodegradable sheets of the present invention, a multilayer sheet may be employed in which a non-foam sheet made of a biodegradable polymer resin made of a polylactic acid polymer or a petrochemical resin is laminated on at least one side of an extruded foam sheet made of a PLA-based polymer.

More preferably, 0.05 to 4 parts by weight of a chain extender, 0.01 to 4 parts by weight of any foaming nucleating agent selected from the group consisting of talc, silica, and calcium stearate, based on 100 parts by weight of the biodegradable polymer resin made of polylactic acid polymer. At least one side of the extrusion foam sheet is compressed and foamed by mixing 1 to 30 parts by weight of a physical foaming agent, and contains an inorganic antiviral agent containing an inorganic antiviral agent in a biodegradable polymer resin made of a polylactic acid polymer or a petrochemical resin. The non-foam sheet is laminated.

A non-foam sheet containing an inorganic antiviral agent in a biodegradable polymer resin made of a polylactic acid-based polymer or a petrochemical resin is laminated and bonded to at least one surface of the extruded foam sheet, thereby providing strength to the biodegradable sheet. Thickness and strength specifications may change depending on the condition.

At this time, the non-foam sheet preferably has a thickness of 50 to 500㎛. If the thickness of the non-foam sheet is less than 50㎛, there is a problem that the thickness becomes uneven during the extrusion lamination process, and if it exceeds 500㎛, the foam layer has a thickness of 50 to 500㎛. This is undesirable as the cell structure becomes unstable.

(6) Inorganic antiviral active layer

In addition, the biodegradable egg egg tray with antiviral properties of the present invention includes a bottom plate or a transparent polylactic acid (PLA) non-foam sheet; Opaque PLA non-foam sheet; Extrusion foam sheet made of PLA-based polymer; And on at least one side of the extruded foam sheet, a multilayer sheet in which a non-foam sheet made of a biodegradable polymer resin made of polylactic acid polymer or a petrochemical resin is laminated,

An inorganic antiviral active layer can be formed by applying an active layer solution containing a single or mixed form selected from inorganic antiviral agents and dispersants.

More preferably, the inorganic antiviral active layer is formed on a multilayer sheet in which the biodegradable non-foam sheet 50 is laminated on at least one side of the extruded foam sheet, thereby providing not only strength but also gas barrier properties, and the foam base sheet. It is possible to fundamentally prevent virus penetration inside the foam cell of (11).

In the above, the inorganic antiviral agent is the same as previously described.

In addition, dispersants are generally selected from human-safe substances known as food additives and are employed from components that are compatible with biodegradable raw resins, especially PLA. Preferably, at least one selected from the group consisting of polyethylene glycol (PEG), citric acid, lactic acid, and polylactic acid (PLA). use. The polylactic acid (PLA) may be contained as a dispersion medium or vehicle in the base layer solution.

The active layer solution containing a single or mixed form selected from the inorganic antiviral agent and dispersant uses a dispersant as a component miscible with PLA, so it is selected from the group of solvents that can dissolve the dispersant and have excellent volatility. Preferably, tetrahydrofuran (THF), chlorinated organic solvents including chloroform, acetonitrile, dioxane and dimethylformamide (DMF), dimethylacetamide (DMAc), ethanol, methanol, normal-propyl alcohol or iso-propyl alcohol. Alcohols selected from, It is selected from the group of solvents consisting of chlorinated organic solvents including chloroform, benzene, toluene, acetonitrile, and dioxane, and is dispersed in one or more.

At this time, the inorganic antiviral active layer can be formed by a coating method using an active layer solution or a spray method using a mist nozzle. The coating method used above can be a Meyer bar or a gravure bar and can be adopted from a known method. Any known method of applying liquid to one surface may be applicable.

At this time, it is preferable that the inorganic antiviral agent is dispersed at 0.01 to 5g/㎡. If it is dispersed at 0.01g/㎡ or less, the gap between the inorganic antiviral agents becomes wider compared to the size of the virus, resulting in insufficient antiviral performance. If dispersed in excess of /㎡, economic feasibility is significantly reduced.

The biodegradable egg egg having the viral properties of the present invention has antiviral properties against one or more selected from the group consisting of filamentous coronavirus (fCoV), influenza A virus (FluA), avian influenza (AI) virus, and porcine virus. This is implemented.

Furthermore, the present invention provides, based on 100 parts by weight of the organic solvent, 0.1 to 20 parts by weight of an inorganic antiviral agent and 0.1 to 0.1 to 20 parts by weight of a dispersing agent selected from the group consisting of polyethylene glycol (PEG), citric acid, lactic acid and polylactic acid (PLA), alone or in mixed form. Provided is a coating composition having antiviral performance containing 20 parts by weight.

The inorganic antiviral agent is used alone or in a mixed form of two or more types selected from the group consisting of the same silver nanoparticle complex, silver ion-containing nanocomposite, copper monovalent compound, zinc oxide nanoparticle, and ferrite nanoparticle as described above.

In the above, the silver nanoparticle composite or silver ion-containing nanocomposite is any selected from the group consisting of silica (SiO ₂ ), minerals including alumina, zeolite, sericite, mordenite, cristobalite, and bentonite, talc, cellulose derivatives, paraffin, and wax. It can be used as long as silver nanoparticles or silver ion-containing nanoparticles are adsorbed or combined.

In addition, the ferrite nanoparticles include alpha-ferrite (α-Fe ₂ O ₃ ), zinc ferrite (ZnFe ₂ O ₄ ), manganese ferrite (MnFe ₂ O ₄ ), nickel ferrite (NiFe ₂ O ₄ ), and iron hydroxide ( It is a combination of at least one selected from the group consisting of α-FeOOH).

The organic solvent can be selected from the group of solvents that can dissolve inorganic antiviral agents and dispersants and have excellent volatility.

Preferably, tetrahydrofuran (THF), chlorinated organic solvents including chloroform, acetonitrile, dioxane and dimethylformamide (DMF), dimethylacetamide (DMAc), ethanol, methanol, normal-propyl alcohol or iso-propyl alcohol. Alcohols selected from, Chlorinated organic solvents including chloroform, benzene, toluene, acetonitrile, and dioxane are used.

In the examples of the present invention, 1,4-dioxane and chloroform are used, but the present invention is not limited thereto.

Hereinafter, the present invention will be described in more detail through examples.

These examples are intended to illustrate the present invention in more detail, and the scope of the present invention is not limited to these examples.

<Example 1>

Mix 1 part by weight of ZnO nanoparticles with 100 parts by weight of PLA resin (Lumini L175 from Total Corbion), mix well using a general mixer such as a tumbling mixer, and then produce pellets with a uniform composition using a twin-screw extruder with an internal diameter of 65 mm. was manufactured. At this time, the sheet was extruded by setting a temperature profile of 260/220/230/230/180/150°C in the direction from the hopper inlet to the extrusion die. The pellets were fed into a first extruder with an inner diameter of 90 mm as raw materials, and an extruded non-foamed sheet was manufactured using a tandem extruder connected to a first extruder with an inner diameter of 90 mm and a second extruder with an inner diameter of 120 mm.

The polylactic acid resin particles were supplied to the first extruder, heated, melted and kneaded, and then pressurized into the first extruder to maintain a residence time of 10 minutes. At this time, the heating melting temperature was maintained at 170 to 230°C based on the resin temperature. Next, the temperature of the melt mixed reactant was slightly reduced in the second extruder connected to the first extruder to bring the resin temperature to 150°C.

Thereafter, a PLA biodegradable sheet containing ZnO (referred to as “nZnO”) with a thickness of 300 μm was manufactured by discharging in the extrusion direction from an annular die having a cylindrical slit with a diameter of 110 mm and a slit spacing of 0.5 mm.

Using the prepared PLA biodegradable sheet, an egg nest was manufactured by injection molding into a bottom plate with three concave egg nest grooves arranged to accommodate eggs and a detachable lid that covers the entire egg nest groove of the bottom plate.

<Example 2>

PLA mixed with ZnO/CuI was prepared in the same manner as Example 1, except that 1 part by weight of ZnO nanoparticles and 1 part by weight of CuI were mixed with 100 parts by weight of PLA resin (Lumini L175 from Total Corbion). An egg egg was manufactured in the same manner as in Example 1, except that a biodegradable sheet (referred to as “CuZn”) was manufactured and injection molded.

<Example 3>

Same as Example 1, except that 1 part by weight of silica particles (AgNPs) combined with silver ions and zinc ions as a silver ion-containing nanocomposite were mixed with 100 parts by weight of PLA resin (Lumini L175 from Total Corbion). An egg egg was manufactured in the same manner as in Example 1, except that a PLA biodegradable sheet (referred to as "AgNP") mixed with a composite containing silver ion-containing nanoparticles was manufactured and injection molded. .

<Example 4>

The same procedure as Example 1 was performed, except that 1 part by weight of CuI was mixed with 100 parts by weight of PLA resin (Lumini L175 from Total Corbion), and a PLA biodegradable sheet containing CuI (referred to as “CuI”) was prepared. ) was manufactured and injection molded, and an egg egg was manufactured in the same manner as in Example 1.

<Example 5>

Except that 1 part by weight of ZnO nanoparticles, 1 part by weight of silica particles (AgNPs) combined with silver and zinc ions, and 1 part by weight of CuI were mixed with 100 parts by weight of PLA resin (Lumini L175 from Total Corbion). Same as Example 1, except that a PLA biodegradable sheet (referred to as "nZnAgCu") mixed with ZnO/silver ion-containing nanocomposite/CuI was manufactured and injection molded in the same manner as Example 1. The egg nanjwa was produced by performing the following steps.

<Example 6>

Based on 100 parts by weight of PLA resin (Hisun's Revode 190), it contains 1.0 parts by weight of an epoxy chain extender as a chain extender, 1.8 parts by weight of talc with a size of 0.1 to 5㎛ as a foaming nucleating agent, and 1.0 parts by weight of a plasticizer (Acetyl tributyl citrate). 1 part by weight and 1 part by weight of ZnO nanoparticles are mixed, mixed well using a general mixer such as a tumbling mixer, and then manufactured into pellets of uniform composition using a twin-screw extruder with an inner diameter of 65 mm, and then extruded into a pellet with an inner diameter of 90 mm. Raw materials were put into the first extruder, and an extrusion foam sheet was manufactured using a tandem extruder connected to a first extruder with an inner diameter of 90 mm and a second extruder with an inner diameter of 120 mm.

The polylactic acid resin particles were supplied to the first extruder and heated, melted and kneaded, and then 2.5 parts by weight of butane as a foaming agent was pressurized into the first extruder and the residence time was maintained at 10 minutes. Afterwards, using a separate T-die extruder, PLA resin containing ZnO was extruded on one side of the foam sheet to form a lamination coating layer with a thickness of 300㎛.

The sheet was manufactured and injection molded to produce an egg seat consisting of a bottom plate with three concave egg seat grooves arranged to accommodate eggs, and an integrated lid that is connected to the bottom plate and covers the entire egg seat groove of the bottom plate.

<Example 7>

Except that in Example 4, instead of PLA, a PLA-based non-foam sheet made of a raw material resin containing 25/55/20% by weight of PLA/PBAT/CaCO ₃ (filler) was manufactured and injection molded. An egg egg was produced in the same manner as in Example 6.

<Example 8>

Except that in Example 4, instead of PLA, a PLA-based non-foam sheet made of raw material resin consisting of 15/55/30% by weight of PBS/PBAT/TPS (modified starch) was manufactured and injection molded. An egg egg was produced in the same manner as in Example 6.

<Example 9>

For 100 parts by weight of PLA resin (Lumini L175 from Total Corbion), 1 part by weight of ZnO nanoparticles and 0.01 parts by weight of ferrite nanoparticles were mixed to produce a PLA biodegradable sheet containing ZnO/ferrite (referred to as "ZnOFe"). An egg egg was manufactured in the same manner as in Example 1, except that one exception was made. At this time, the ferrite nanoparticles were alpha-ferrite (α-Fe ₂ O ₃ ), zinc ferrite (ZnFe ₂ O ₄ ), and manganese ferrite (MnFe ₂ O ₄ ).

<Comparative Example 1>

It was performed in the same manner as Example 1, except that the PLA resin (Lumini L175 from Total Corbion) used in Example 1 was performed without mixing an inorganic antiviral agent.

<Experimental Example 1> Evaluation of the morphology of the sheet

For the 300㎛ thick PLA biodegradable sheet containing the inorganic antiviral agent prepared in Examples 1 to 5, the cross section of the sheet was photographed using an electron microscope (manufactured by Bruker).

Figures 5 to 9 show cross-sectional photographs of the PLA biodegradable sheets prepared in each example, showing overall good dispersion of the inorganic antiviral agent and dispersion of individual particles or two or more types of aggregated composite particles with a size of 100 to 300 nm. The results were confirmed.

In particular, in the PLA biodegradable sheet containing the silver ion-containing nanocomposite of Example 3, it was confirmed that more than 50% of individual particles or two or more types of aggregated composite particles were 150 to 200 nm.

<Experimental Example 2> Antiviral performance evaluation

The antiviral performance of the PLA biodegradable sheets containing inorganic antiviral agents prepared in Examples 1 to 8 was evaluated against influenza virus (FluA) or filamentous coronavirus (fCoV) [Government appearance Researcher test evaluation].

Specifically, 5 μl of the virus solution was applied twice to the surface of the sheet (1 cm It was carried out in .

The evaluation standard was to observe virus reduction 10 minutes and 2 hours after inoculation with the virus, and Table 1 below shows the virus reduction of the antiviral effect 2 hours after inoculation in log. At this time, the higher the number, the higher the removal rate.

From the results in Table 1 above, the inorganic antiviral agent contained in the biodegradable sheet of the present invention alone or two or more aggregated composite particles were dispersed with a particle size of 100 to 900 nm, and in Examples 1 to 9, respectively, In the case of PLA biodegradable sheets containing inorganic antiviral agents selected from the group consisting of ion-containing nanocomposites, copper monovalent compounds, zinc oxide nanoparticles, and ferrite nanoparticles alone or in a mixture of two or more types, influenza virus (FluA) or Fila It showed remarkable antiviral performance against human coronavirus (fCoV) compared to Comparative Example 1.

Therefore, egg eggs made using PLA biodegradable sheets are made by dispersing the inorganic antiviral agent alone or two or more aggregated composite particles into a particle size of 100 to 900 nm, so that the particle size is large enough to prevent the inorganic antiviral agent from penetrating the skin. While meeting the requirements, excellent antiviral performance can be realized by inactivating the virus before entering the human body by contact with an external virus or inhibiting RNA replication even if infected.

<Examples 9 to 23>

A coating composition with antiviral properties is applied to one side of the biodegradable base sheet made of biodegradable raw resin using Meyerbar coating or mist spray to form an inorganic antiviral active layer, and the sheet manufactured according to Table 2 below is injection molded. Thus, egg nanjja was manufactured.

<Experimental Example 3> Antiviral performance evaluation

Antiviral biodegradable PLA prepared in Examples 9 to 23 above 5㎕ influenza A virus (FluA), (Human, H3N2) solution was repeatedly added to the surface of the sheet cut into a circle with a diameter of 1cm. MDCK cells were used as the cell line, and the reaction time was 30 minutes at room temperature (23°C). Regarding this, the antiviral performance was evaluated by virus titration using the CPE/MTT assay.

In addition, 5㎕ filamentous coronavirus (fCoV) solution was repeatedly added dropwise to the surface of an antiviral biodegradable sheet (1cm In this regard, the antiviral performance was evaluated by virus titration using the CPE/MTT essay method [government-funded research institute test evaluation].

The results are listed in Table 3 .

From the results in Table 3, the antiviral biodegradable sheet of the present invention is composed of inorganic antiviral agents alone or two or more aggregated composite particles dispersed in a particle size of 100 to 900 nm, and is effective against influenza A virus (FluA) and filamentous coronavirus. For the virus (fCoV), the virus reduction rate was up to 99.999% within 30 minutes of contact with the virus.

In the above, the present invention has been described in detail only with respect to the described embodiments, but it is clear to those skilled in the art that various changes and modifications are possible within the technical scope of the present invention, and it is natural that such changes and modifications fall within the scope of the appended patent claims.

10: Biodegradable non-foaming base sheet
11: Biodegradable foam base sheet
21, 31, 41, 42: Inorganic antiviral agent
30: Non-foam sheet containing polylactic acid polymer and inorganic antiviral agent
40: Inorganic antiviral active layer
50: Non-foam sheet made of biodegradable polymer resin made of polylactic acid-based polymer or petrochemical resin

Claims (18)

An egg seat consisting of a bottom plate with one or more concave egg seat grooves arranged to accommodate eggs, a detachable lid that covers the entire egg seat groove of the bottom plate, or an integrated lid that is connected to the bottom plate and covers the entire egg seat groove of the bottom plate. Because,
The bottom plate or the bottom plate and lid
polylactic acid-based resin; or
A composite degradable polymer resin composed of a biodegradable resin and a petrochemical resin; composed of a biodegradable sheet prepared by dispersing an inorganic antiviral agent alone or two or more aggregated composite particles with a particle size of 100 to 900 nm,
The bottom plate or the bottom plate and lid
Transparent polylactic acid (PLA) non-foam sheet;
Opaque PLA non-foam sheet;
Extrusion foam sheet made of PLA-based polymer; and
A multilayer sheet in which a non-foam sheet made of a polylactic acid-based resin or a composite degradable polymer resin made of a biodegradable resin and a petrochemical resin is laminated on at least one side of the extruded foam sheet; It is made of any one material selected from the group consisting of , A biodegradable egg egg with antiviral performance, characterized in that the bottom plate and lid are combined with the same sheet material or different sheet materials. The method of claim 1, wherein the inorganic antiviral agent is selected from the group consisting of silver nanoparticle complexes, silver ion-containing nanocomposites, copper monovalent compounds, zinc oxide nanoparticles, and ferrite nanoparticles, either alone or in the form of a mixture of two or more types. A biodegradable egg egg with antiviral properties. The method of claim 2, wherein the silver nanoparticle composite or silver ion-containing nanocomposite is made of minerals including silica (SiO ₂ ), alumina, zeolite, sericite, mordenite, cristobalite, and bentonite, talc, cellulose derivatives, paraffin, and wax. A biodegradable egg egg with antiviral performance, characterized in that silver nanoparticles or silver ion-containing nanoparticles are adsorbed or bound to any one selected from the group consisting of. The method of claim 2, wherein the ferrite nanoparticles are alpha-ferrite (α-Fe ₂ O ₃ ), zinc ferrite (ZnFe ₂ O ₄ ), manganese ferrite (MnFe ₂ O ₄ ), nickel ferrite (NiFe ₂ O ₄ ), and A biodegradable egg egg with antiviral properties, characterized in that it is a combination of at least one selected from the group consisting of iron hydroxide (α-FeOOH). The method of claim 1, wherein 0.1 to 60 parts by weight of an inorganic antiviral agent alone or two or more types of aggregated composite particles are contained, based on 100 parts by weight of the polylactic acid-based resin or composite decomposable polymer resin. Biodegradable egg yolk. The method of claim 1, wherein the biodegradable resin is polylactic acid (PLA), polyhydroxyalkanoates (PHA), polybutylene adipate-co-terephthalate (PBAT), Polybutylene succinate-co-adipate (PBSA), polybutylene succinate adipate-co-terephthalate (PBSAT), polybutylene succinate , PBS), polyvinyl alcohol (PVA), poly glycolic acid (PGA), polylactic-co-glycolic acid (PLGA), and polycaprolactone , PCL), modified starch resin, and thermoplastic starch (TPS). Biodegradable egg eggs with antiviral properties, characterized in that they are used alone or in a mixed form of two or more types selected from the group consisting of modified starch resin and thermoplastic starch (TPS). delete The biodegradable egg egg tray with antiviral properties according to claim 1, wherein in the multi-layer sheet, a non-foam sheet is laminated on the inner surface of the bottom plate made of an extruded foam sheet or the outer surface of the bottom plate. The biodegradable egg egg cake with antiviral performance according to claim 1, wherein the non-foam sheet contains 0.1 to 60 parts by weight of an inorganic antiviral agent based on 100 parts by weight of biodegradable polymer resin or petrochemical resin. The biodegradable egg egg with antiviral performance according to claim 1, wherein the non-foaming sheet has a thickness of 50 to 500㎛. An egg seat consisting of a bottom plate with one or more concave egg seat grooves arranged to accommodate eggs, a detachable lid that covers the entire egg seat groove of the bottom plate, or an integrated lid that is connected to the bottom plate and covers the entire egg seat groove of the bottom plate. Because,
The bottom plate or the bottom plate and lid
Transparent polylactic acid (PLA) non-foam sheet;
Opaque PLA non-foam sheet;
Extrusion foam sheet made of PLA-based polymer; and
At least one side of any one sheet selected from the group consisting of a multilayer sheet in which a non-foam sheet made of a polylactic acid-based resin or a composite degradable polymer resin made of a biodegradable resin and a petrochemical resin is laminated on at least one side of the extruded foam sheet. ,
An inorganic antiviral active layer is formed by applying an active layer solution containing a single or mixed form selected from inorganic antiviral agents and dispersants,
A biodegradable egg egg tray with antiviral performance, characterized in that the bottom plate and lid are combined with the same sheet material or different sheet materials. The method of claim 11, wherein the inorganic antiviral active layer is formed by a coating method or a spray method using a mist nozzle,
A biodegradable egg egg with antiviral performance, characterized in that the inorganic antiviral agent is dispersed at 0.01 to 5 g/㎡. The method according to any one of claims 1 to 6 and 8 to 12, wherein the antiviral activity is effective against filamentous coronavirus (fCoV), influenza A virus (FluA), avian influenza (AI) virus, and swine. A biodegradable egg egg that has antiviral properties implemented by one or more antiviral properties selected from the group consisting of viruses. The method of claim 11, wherein the inorganic antiviral active layer is
For 100 parts by weight of organic solvent,
0.1 to 20 parts by weight of an inorganic antiviral agent and
Antiviral performance, characterized in that it is formed of a coating composition having antiviral performance containing 0.1 to 20 parts by weight of a dispersant in the form of a single or mixed dispersant selected from the group consisting of polyethylene glycol (PEG), citric acid, lactic acid, and polylactic acid (PLA). Eggplant is a biodegradable egg nanjwa. delete delete delete The method of claim 14, wherein the organic solvent is tetrahydrofuran (THF), a chlorinated organic solvent including chloroform, acetonitrile, dioxane, dimethylformamide (DMF), dimethylacetamide (DMAc), ethanol, methanol, normal- Alcohols selected from propyl alcohol or iso-propyl alcohol, A biodegradable egg egg with antiviral performance, characterized in that it contains at least one of the group consisting of chlorinated organic solvents including chloroform, benzene, toluene, acetonitrile, and dioxane.