KR102595705B1 - 조직학적 조직 검체 프로세싱 개선 - Google Patents
조직학적 조직 검체 프로세싱 개선 Download PDFInfo
- Publication number
- KR102595705B1 KR102595705B1 KR1020207001883A KR20207001883A KR102595705B1 KR 102595705 B1 KR102595705 B1 KR 102595705B1 KR 1020207001883 A KR1020207001883 A KR 1020207001883A KR 20207001883 A KR20207001883 A KR 20207001883A KR 102595705 B1 KR102595705 B1 KR 102595705B1
- Authority
- KR
- South Korea
- Prior art keywords
- reagent
- tissue
- container
- retort
- tissue processor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 12
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 12
- 238000009835 boiling Methods 0.000 description 12
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- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 4
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- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 238000013019 agitation Methods 0.000 description 3
- 150000001298 alcohols Chemical class 0.000 description 3
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- UOCLXMDMGBRAIB-UHFFFAOYSA-N 1,1,1-trichloroethane Chemical compound CC(Cl)(Cl)Cl UOCLXMDMGBRAIB-UHFFFAOYSA-N 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
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- 239000000654 additive Substances 0.000 description 2
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- 238000009833 condensation Methods 0.000 description 2
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- RRKTZKIUPZVBMF-IBTVXLQLSA-N brucine Chemical compound O([C@@H]1[C@H]([C@H]2C3)[C@@H]4N(C(C1)=O)C=1C=C(C(=CC=11)OC)OC)CC=C2CN2[C@@H]3[C@]41CC2 RRKTZKIUPZVBMF-IBTVXLQLSA-N 0.000 description 1
- RRKTZKIUPZVBMF-UHFFFAOYSA-N brucine Natural products C1=2C=C(OC)C(OC)=CC=2N(C(C2)=O)C3C(C4C5)C2OCC=C4CN2C5C31CC2 RRKTZKIUPZVBMF-UHFFFAOYSA-N 0.000 description 1
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- 239000003350 kerosene Substances 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/16—Retorts
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
- G01N35/00613—Quality control
- G01N35/00663—Quality control of consumables
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N2001/315—Basket-type carriers for tissues
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
- G01N35/00613—Quality control
- G01N35/00663—Quality control of consumables
- G01N2035/00673—Quality control of consumables of reagents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Quality & Reliability (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762548638P | 2017-08-22 | 2017-08-22 | |
| US62/548,638 | 2017-08-22 | ||
| PCT/AU2018/050892 WO2019036760A1 (en) | 2017-08-22 | 2018-08-22 | IMPROVEMENTS IN THE TREATMENT OF HISTOLOGIC TISSUE SPECIMENS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20200043976A KR20200043976A (ko) | 2020-04-28 |
| KR102595705B1 true KR102595705B1 (ko) | 2023-10-31 |
Family
ID=65438185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020207001883A Active KR102595705B1 (ko) | 2017-08-22 | 2018-08-22 | 조직학적 조직 검체 프로세싱 개선 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11428700B2 (enExample) |
| EP (2) | EP3625539B1 (enExample) |
| JP (1) | JP7289292B2 (enExample) |
| KR (1) | KR102595705B1 (enExample) |
| CN (1) | CN110869733B (enExample) |
| AU (2) | AU2018322484B2 (enExample) |
| CA (2) | CA3066282C (enExample) |
| WO (1) | WO2019036760A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111141564A (zh) * | 2018-11-02 | 2020-05-12 | 莱卡生物系统努斯洛赫有限责任公司 | 用于提示溶剂的状态的装置、方法和组织处理机 |
| CN111665115A (zh) * | 2020-06-17 | 2020-09-15 | 深圳褀氏生物科技有限公司 | 一种全自动细胞组织制片免疫组化染色机的转盘装置 |
| CN111896353A (zh) * | 2020-07-24 | 2020-11-06 | 南通大学 | 一种小组织块脱水方法 |
| US20230258668A1 (en) * | 2020-07-31 | 2023-08-17 | Leica Biosystems Nussloch Gmbh | Method and apparatus for monitoring concentration of reagent, electronic device, and computer readable storage medium |
| CN115917285B (zh) * | 2020-07-31 | 2025-05-13 | 莱卡生物系统努斯洛赫有限责任公司 | 组织处理器 |
| EP4193137A4 (en) * | 2020-08-10 | 2024-05-22 | Leica Biosystems Nussloch GmbH | Xylene-free tissue processor and method for processing tissue |
| DE102021105932B4 (de) * | 2021-03-11 | 2023-02-16 | Leica Biosystems Nussloch Gmbh | Verfahren zur Gewebeprozessierung und Gewebeprozessor |
| CN113092219B (zh) * | 2021-03-24 | 2025-07-18 | 迪帕微(上海)生物科技有限公司 | 一种硬组织切片防脱预处理装置及防脱预处理方法 |
| KR102734328B1 (ko) | 2021-11-12 | 2024-11-27 | 주식회사 엘지에너지솔루션 | 배터리 모듈 및 이를 포함한 배터리 팩 |
| CN114264537A (zh) * | 2021-12-21 | 2022-04-01 | 达科为（深圳）医疗设备有限公司 | 脱水机及其控制方法、系统、电子设备、可读存储介质 |
| DE102022122439A1 (de) * | 2022-09-05 | 2024-03-07 | Leica Biosystems Nussloch Gmbh | Verfahren zur Gewebeprozessierung und Gewebeprozessor |
| WO2024226850A1 (en) * | 2023-04-25 | 2024-10-31 | Rensselaer Polytechnic Institute | Systems and methods for tissue staining |
| KR102636484B1 (ko) * | 2023-07-13 | 2024-02-15 | 한국원자력의학원 | 수술용 검체의 포르말린 균일 고정틀 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100112624A1 (en) * | 2008-10-31 | 2010-05-06 | Leica Biosystems Nussloch Gmbh | Method for operating a tissue processor, and tissue processor |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA626268A (en) * | 1961-08-29 | H. Strauss Herman | Container and a handle | |
| US3889014A (en) | 1972-02-22 | 1975-06-10 | Triangle Biomedical Equipment | Automatic electron microscopy tissue processor method |
| US3995803A (en) * | 1974-09-03 | 1976-12-07 | Uitz Mark D | Foldable bicycle basket |
| US5127537A (en) * | 1991-06-05 | 1992-07-07 | Graham Donald R | Tissue cassette with a living hinge |
| US5427308A (en) * | 1994-08-10 | 1995-06-27 | Eco-Cool, Inc. | Container with integral handles and locking tabs |
| JP2000028501A (ja) * | 1998-07-15 | 2000-01-28 | Chiyoda Manufacturing Co Ltd | 組織片処理用バスケット |
| US6047976A (en) * | 1998-09-16 | 2000-04-11 | Wang; King-Sheng | Portable storage container |
| CN100473990C (zh) * | 2001-10-01 | 2009-04-01 | 徠卡生物体系墨尔本控股有限公司 | 组织处理器 |
| US7850912B2 (en) * | 2003-05-14 | 2010-12-14 | Dako Denmark A/S | Method and apparatus for automated pre-treatment and processing of biological samples |
| US8554372B2 (en) | 2003-09-29 | 2013-10-08 | Leica Biosystems Melbourne Pty Ltd | System and method for histological tissue specimen processing |
| EP1749198B1 (en) | 2004-05-25 | 2015-03-25 | Leica Biosystems Melbourne Pty Ltd | Method of treatment of tissue processing fluid and apparatus therefor |
| CN101351153A (zh) * | 2006-03-22 | 2009-01-21 | 松下电器产业株式会社 | 生物传感器和成分浓度测量装置 |
| DE102008039876B4 (de) | 2008-08-27 | 2014-08-21 | Leica Instruments (Singapore) Pte. Ltd. | Verfahren zum Steuern eines Gewebeprozessors und Gewebeprozessor |
| US20100099199A1 (en) | 2008-10-22 | 2010-04-22 | Leica Biosystems Nussloch Gmbh | Method and apparatus for ascertaining reagent quality |
| DE102008054066B4 (de) * | 2008-10-31 | 2015-03-19 | Leica Biosystems Nussloch Gmbh | Verfahren zum Bearbeiten von Gewebeproben unter Verwendung eines Sensors |
| DE102009038481B4 (de) * | 2009-08-21 | 2011-09-01 | Leica Biosystems Nussloch Gmbh | Verfahren zum Betreiben eines Gewebeprozessors |
| US20130196339A1 (en) * | 2012-01-31 | 2013-08-01 | Thermo Shandon Limited | Slide pocket |
| GB2523556A (en) * | 2014-02-26 | 2015-09-02 | Cellpath Ltd | Histology cassette stack |
| JP2016035386A (ja) * | 2014-08-01 | 2016-03-17 | 国立大学法人浜松医科大学 | 染色バスケット |
| US20160175173A1 (en) * | 2014-12-19 | 2016-06-23 | Flo's Friends, Llc | Portable personal hygiene products holder |
| US10491711B2 (en) | 2015-09-10 | 2019-11-26 | EEVO, Inc. | Adaptive streaming of virtual reality data |
| GB2549978A (en) * | 2016-05-05 | 2017-11-08 | Thermo Shandon Ltd | Tissue processing apparatus for processing biological tissue |
-
2018
- 2018-08-22 WO PCT/AU2018/050892 patent/WO2019036760A1/en not_active Ceased
- 2018-08-22 KR KR1020207001883A patent/KR102595705B1/ko active Active
- 2018-08-22 JP JP2020505829A patent/JP7289292B2/ja active Active
- 2018-08-22 CN CN201880045954.0A patent/CN110869733B/zh active Active
- 2018-08-22 AU AU2018322484A patent/AU2018322484B2/en active Active
- 2018-08-22 EP EP18849016.3A patent/EP3625539B1/en active Active
- 2018-08-22 EP EP25169488.1A patent/EP4560321A3/en active Pending
- 2018-08-22 CA CA3066282A patent/CA3066282C/en active Active
- 2018-08-22 US US16/621,362 patent/US11428700B2/en active Active
- 2018-08-22 CA CA3225153A patent/CA3225153A1/en active Pending
-
2022
- 2022-07-25 US US17/872,953 patent/US12399191B2/en active Active
-
2023
- 2023-11-27 AU AU2023270360A patent/AU2023270360B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100112624A1 (en) * | 2008-10-31 | 2010-05-06 | Leica Biosystems Nussloch Gmbh | Method for operating a tissue processor, and tissue processor |
Non-Patent Citations (1)
| Title |
|---|
| Haeckel, R. "Recommendations for definition and determination of carry-over effects." Journal of Automatic Chemistry 10.4 (1988): 181-183.* |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4560321A3 (en) | 2025-08-13 |
| EP3625539A4 (en) | 2021-03-10 |
| JP7289292B2 (ja) | 2023-06-09 |
| US11428700B2 (en) | 2022-08-30 |
| AU2018322484B2 (en) | 2023-09-14 |
| AU2023270360B2 (en) | 2024-10-17 |
| CA3225153A1 (en) | 2019-02-28 |
| US20200174029A1 (en) | 2020-06-04 |
| CN110869733B (zh) | 2023-08-08 |
| CA3066282C (en) | 2024-04-30 |
| EP3625539B1 (en) | 2025-05-21 |
| CA3066282A1 (en) | 2019-02-28 |
| US20230061034A1 (en) | 2023-03-02 |
| EP3625539A1 (en) | 2020-03-25 |
| WO2019036760A1 (en) | 2019-02-28 |
| AU2023270360A1 (en) | 2023-12-14 |
| KR20200043976A (ko) | 2020-04-28 |
| CN110869733A (zh) | 2020-03-06 |
| US12399191B2 (en) | 2025-08-26 |
| EP4560321A2 (en) | 2025-05-28 |
| AU2018322484A1 (en) | 2020-01-02 |
| JP2020531804A (ja) | 2020-11-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20200120 Patent event code: PA01051R01D Comment text: International Patent Application |
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| PG1501 | Laying open of application | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20210812 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
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