KR102551684B1 - Device for treating a wound using redox activity - Google Patents

Abstract

The present invention relates to a device for treating a wound using an oxidation-reduction reaction. The present invention includes a base sheet, an electrode unit attached to the base sheet and having electrode materials having different polarities, and an absorption layer attached to the base sheet and activating the electrode material to be electrically connected by absorbed exudate. do.

Description

Device for treating a wound using redox reaction {Device for treating a wound using redox activity}

The present invention relates to a device for treating a wound using an oxidation-reduction reaction.

Materials used in the treatment of burns and wounds should reduce the period of wound healing due to epithelialization, should not cause discomfort due to bleeding or pain during replacement, and should be capable of minimizing scar formation after epithelialization. In addition, the secondary infection rate (secondary infection rate) is low, manufacturing and storage should be easy to be readily available. Based on this, in order to promote wound healing, moist wound healing is applied to the wound to be used as a variety of biological dressings, and has an effect of helping epithelial regeneration.

Various bands are used to treat skin wounds. These bands can be largely classified into two types. One is a band that is used by applying a therapeutic ointment to the skin where the wound has occurred and then attached to the wound to prevent secondary bacterial infection, and the other is a band that is used by applying a treatment ointment to the skin where the wound has occurred. In order to prevent scarring due to abnormal expression of cells due to poor movement of healing cells around the wound due to dryness after being in contact with air, a porous organic material containing a large amount of moisture is attached to the wound to provide moisture. It is a band that prevents necrotic tissue while allowing the release slowly.

Currently, as a dressing method for healing wounds on the skin, dry-dressing using gauze, wet-dressing method using hydrophilic polymer, and electric field are used. treatments, etc.

The general dry dressing method is to disinfect the wound area on the skin and then block it from the outside to prevent secondary infection and prevent the wound from becoming infected so that the wound heals. The wet dressing method blocks the wound area from the external environment to prevent secondary infection. Based on the function of preventing infection, the hydrophilic polymer absorbs the exudate generated from the wound and suppresses the rapid evaporation of moisture to create a moist atmosphere in the wound area, thereby reducing the scab caused by the dryness of the wound surface. It has the function of helping wound healing and minimizing scarring by facilitating the flow of healing cells and ions that have a positive effect on healing.

An object of the present invention is to provide a wound healing device using an oxidation-reduction reaction that can restore a wound by forming an electric current or electric field by an oxidation-reduction reaction in a wound area. However, these tasks are illustrative, and the scope of the present invention is not limited thereby.

One aspect of the present invention is a base sheet, an electrode unit attached to the base sheet and having electrode materials having different polarities, and attached to the base sheet, activated to electrically connect the electrode material by absorbed exudate. Provided is a device for treating a wound using an oxidation-reduction reaction having an absorbent layer.

In addition, the electrode unit is provided with at least one, and has a first electrode pattern disposed on one side of the base sheet, and a second electrode pattern provided with at least one or more and disposed spaced apart from the first electrode pattern. can

In addition, the electrode unit may have a first electrode pattern forming a closed curve along the base sheet, and a second electrode pattern disposed inside the first electrode pattern.

In addition, the absorption layer is disposed to cover the first electrode pattern and the second electrode pattern, or disposed to be spaced apart between the first electrode pattern and the second electrode pattern, and the first electrode pattern by the absorbed exudate. And it may be extended to the second electrode pattern.

In addition, the absorbent layer may include hydrocolloid or polyurethane.

Another aspect of the present invention includes a base sheet and an absorption unit attached to the base sheet, in which an electrode material in particle form is mixed with an absorbent member, and the electrode material is activated when exudate is absorbed into the absorbent member. A device for treating a wound using a reduction reaction is provided.

In addition, in the absorption unit, first electrode materials and second electrode materials activated with different polarities may be disposed inside the absorption member.

In addition, the absorption unit includes a first absorption layer in which a first electrode material is disposed inside the absorption member, and a second absorption layer in which a second electrode material having a polarity different from that of the first electrode material is disposed in the inside of the absorption member. can be provided

Also, in the absorption unit, the first absorption layer and the second absorption layer may be alternately stacked.

In addition, in the absorbent unit, the first absorbent layer and the second absorbent layer may be disposed adjacent to each other on the base sheet.

In addition, the absorption unit may further include a third absorption layer disposed between the first absorption layer and the second absorption layer, but not including the electrode material and having the absorption member.

In addition, the absorbent member may include hydrocolloid or polyurethane.

Another aspect of the present invention is a base sheet, a first electrode pattern formed of a first electrode material disposed on the base sheet, and disposed on the base sheet, having a polarity different from that of the first electrode material, but in the form of particles. Provided is an apparatus for treating an affected area using an oxidation-reduction reaction including an absorption unit having an absorption member in which a material of the second electrode is mixed.

In addition, the absorption unit may electrically connect the first electrode material and the second electrode material when the exudate is absorbed into the absorbent member.

In addition, the absorption unit may be disposed spaced apart from the first electrode pattern, and may expand to contact the first electrode pattern when activated.

In addition, it may further include a second electrode pattern disposed spaced apart from the first electrode pattern and formed of the second electrode material.

In addition, the absorption unit may further include the first electrode material in the form of particles mixed with the absorption member.

In addition, the absorbent member may include hydrocolloid or polyurethane.

When the device for treating a wound using an oxidation-reduction reaction according to the present invention is electrically activated when attached to a wound, it can recover the wound quickly and safely. When the absorbent member absorbs exudate or the like, electrode materials having different polarities are electrically activated to emit electrons to the affected area and form an electric field. The affected area can be quickly and safely recovered by electrical stimulation, and scarring can be minimized because the device for treating the affected area using an oxidation-reduction reaction maintains a wet state.

The device for treating a wound using an oxidation-reduction reaction according to the present invention generates electrical stimulation only when attached to the affected area, so that the safety and predictability of the dressing device can be ensured, and electrical stimulation can be stably provided to the affected area.

1 is a diagram showing an apparatus for treating a wound using an oxidation-reduction reaction according to a first embodiment of the present invention.
2 is a cross-sectional view of an apparatus for treating a diseased area using an oxidation-reduction reaction attached to a diseased area.
3a and 3b are modified examples of the device for treating a damaged area using the oxidation-reduction reaction of FIG. 1 .
4a to 4e are other modified examples of the wound healing device using the oxidation-reduction reaction of FIG. 1 .
FIG. 5 is a diagram showing an apparatus for treating a wound using an oxidation-reduction reaction according to a second embodiment of the present invention.
FIG. 6 is a cross-sectional view of an apparatus for treating a diseased area using the oxidation-reduction reaction of FIG. 5 attached to a diseased area.
7a and 7b are modified examples of the device for treating an affected area using the oxidation-reduction reaction of FIG. 5 .
8 is a diagram showing an apparatus for treating a wound using an oxidation-reduction reaction according to a third embodiment of the present invention.
FIG. 9 is a cross-sectional view of the device for treating an affected area using the oxidation-reduction reaction of FIG. 8 .
FIG. 10 is a diagram showing a wound healing device using an oxidation-reduction reaction according to a fourth embodiment of the present invention.
FIG. 11 is a view showing an apparatus for treating a wound using an oxidation-reduction reaction according to a fifth embodiment of the present invention.
FIG. 12 is a diagram showing a wound healing device using an oxidation-reduction reaction according to a sixth embodiment of the present invention.
FIG. 13 is a view showing an apparatus for treating a wound using an oxidation-reduction reaction according to a seventh embodiment of the present invention.
14 is a diagram showing a device for treating a wound using an oxidation-reduction reaction according to an eighth embodiment of the present invention.
15a to 15d are modified examples of the device for treating an affected area using the oxidation-reduction reaction of FIG. 14 .
16 is a view showing a method of treating a wound using an oxidation-reduction reaction according to another embodiment of the present invention.
17 is a photograph comparing the treatment effect using the device for treating an affected area using an oxidation-reduction reaction according to the present invention.

Since the present invention can apply various transformations and have various embodiments, specific embodiments will be illustrated in the drawings and described in detail in the detailed description. Effects and features of the present invention, and methods for achieving them will become clear with reference to the embodiments described later in detail together with the drawings. However, the present invention is not limited to the embodiments disclosed below and may be implemented in various forms.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings, and when describing with reference to the drawings, the same or corresponding components are assigned the same reference numerals, and overlapping descriptions thereof will be omitted. .

In the following embodiments, terms such as first and second are used for the purpose of distinguishing one component from another component without limiting meaning.

In the following examples, expressions in the singular number include plural expressions unless the context clearly dictates otherwise.

In the following embodiments, terms such as include or have mean that features or components described in the specification exist, and do not preclude the possibility that one or more other features or components may be added.

In the following embodiments, when a part such as a film, region, component, etc. is said to be on or on another part, not only when it is directly above the other part, but also when another film, region, component, etc. is interposed therebetween. Including if there is

In the drawings, the size of components may be exaggerated or reduced for convenience of description. For example, since the size and thickness of each component shown in the drawings are arbitrarily shown for convenience of description, the present invention is not necessarily limited to the illustrated bar.

Hereinafter, a device for treating a wound using an oxidation-reduction reaction is a device using current generated from an oxidation-reduction reaction. A wound healing device using an oxidation-reduction reaction forms a relatively low level electric field (LLEF) or a relatively low level micro-current (LLMC) when the oxidation-reduction reaction is activated. ) is a device that forms A wound healing device using an oxidation-reduction reaction can increase the recovery speed of a wound with electrical energy generated by oxidation and reduction reactions of a galvanic cell.

Hereinafter, “activation” is defined as supplying current in a wound healing device using an oxidation-reduction reaction. Specifically, electrode materials having different polarities are electrically connected, and electrons and ions move.

Hereinafter, the affected part (W) is an object to which a device using reverse electrodialysis and oxidation-reduction reaction is attached, and a drug is delivered using an electrical response or electrical stimulation is applied to the skin, such as animal skin or human skin. can

In the following drawings, electrons are shown as moving along the affected portion W or the absorbing member, but embodiments of the present invention are not limited thereto. In an activated state, since both the base sheet and the skin EP may have conductivity, electrons may move through any one of the affected area W, the skin, and the affected area treatment device.

1 is a diagram showing a wound treatment device 100 using an oxidation-reduction reaction according to a first embodiment of the present invention, and FIG. 2 is a diagram showing a wound treatment device 100 using an oxidation-reduction reaction attached to a wound it is a cross section

Referring to FIGS. 1 and 2 , the affected area treatment device 100 using an oxidation-reduction reaction may include a base sheet 110 , an electrode unit 120 , an absorbent layer 130 and a release film 140 .

The base sheet 110 has a predetermined thickness formed to be attached to the affected part (W) of the target object, and may be made of a sheet having flexibility. One side of the base sheet 110 is in close contact with the skin of the object, and the other side is exposed to the outside.

The base sheet 110 may have various sizes and shapes depending on the position of the object to which it is attached. For example, the base sheet 110 may have various shapes such as a circle, a square, a rectangle, and a triangle. However, hereinafter, for convenience of description, an example in which the base sheet 110 has a rectangular shape will be mainly described.

The base sheet 110 may be formed of a material having biocompatibility. The base sheet 110 is a portion that is attached to the skin of a subject, and may be formed of a safe material that does not cause skin trouble even when attached for a long time. For example, the base sheet 110 may be a medical band applicable to a medical dressing.

The electrode unit 120 is attached to the base sheet 110 and may have an electrode material having a polarity. The electrode unit 120 may have a first electrode pattern 121 and a second electrode pattern 122 having different polarities.

At least one first electrode pattern 121 is provided and may be disposed on one side of the base sheet 110 . The first electrode pattern 121 may include a first electrode material. In one embodiment, the first electrode pattern 121 may extend along one side of the base sheet 110 .

At least one second electrode pattern 122 is provided and may be spaced apart from the first electrode pattern 121 . The second electrode pattern 122 may include a second electrode material. In one embodiment, the second electrode pattern 122 may extend along the other side of the base sheet 110 .

In one embodiment, as shown in FIG. 2 , the first electrode pattern 121 and the second electrode pattern 122 may be disposed at the edge of the absorption layer 130 . The first electrode pattern 121 and the second electrode pattern 122 are disposed on the edge of the affected area (W), the absorption layer 130 covers the upper part of the affected area (W), and the first electrode pattern is absorbed by exudate. 121 and the second electrode pattern 122 may be activated.

In one embodiment, as shown in FIG. 2, the first electrode pattern 121 and the second electrode pattern 122 are attached to one surface of the base sheet 110, and the absorption layer 130 is the first electrode pattern 121 and It may be disposed on the base sheet 110 to cover the second electrode pattern 122 . Since the first electrode pattern 121 and the second electrode pattern 122 are attached to the base sheet 110, the electrode unit 120 is not separated from the base sheet 110, and durability can be improved.

The first electrode pattern 121 and the second electrode pattern 122 may have different polarities. The first electrode pattern 121 may include a first electrode material, and the second electrode pattern 122 may include a second electrode material having a different polarity from that of the first electrode material. The first electrode pattern 121 may be formed of only the first electrode material or a mixture of the first electrode material and other materials. Also, the second electrode pattern 122 may be formed of only the second electrode material or may be formed by mixing the first electrode material and other materials.

The first electrode material and the second electrode material are not limited to specific materials, and may be defined as materials capable of forming different electrodes by a potential difference. In addition, the first electrode material and the second electrode material may be formed of a material having biocompatibility. However, hereinafter, for convenience of description, a case in which the first electrode material is silver chloride (AgCl) and the second electrode material is zinc (Zn) will be mainly described.

For example, the first electrode pattern 121 is a cathode electrode, and the second electrode pattern 122 is an anode electrode. If silver chloride (AgCl) is used as the cathode electrode and zinc (Zn) is used as the anode electrode, an oxidation-reduction reaction is generated as follows.

(cathode): AgCl _(s) + e ^- -> Ag (s) + Cl ^- _(aq)

(anode): Zn _(s) -> Zn ²⁺ _(S) + 2e ^-

The absorption layer 130 is attached to the base sheet 110 and can activate electrode materials to be electrically connected by the absorbed exudate (EXD). The absorbent layer 130 may absorb exudate (EXD) such as moisture or exudate generated from a wound, and the absorbed exudate (EXD) may activate the electrode unit 120 .

The absorbent layer 130 may be disposed on one surface of the base sheet 110 . In one embodiment, as shown in FIG. 2 , at least a portion of the electrode unit 120 may be disposed inside the absorption layer 130 . The absorption layer 130 may be disposed to cover the first electrode pattern 121 and the second electrode pattern 122 .

The absorbent layer 130 does not activate the electrode unit 120 in a dry state, but may activate the electrode unit 120 in a wet state. That is, when the affected area treatment device 100 using the oxidation-reduction reaction is not used, the absorption layer 130 does not electrically activate the electrode unit 120 . However, when the affected area treatment device 100 using the oxidation-reduction reaction is attached to the affected area W, the exudate EXD is absorbed by the absorbent member of the absorbent layer 130, and as described above, the first electrode pattern 121 and the second electrode pattern 122 are electrically activated.

The absorption layer 130 may include an absorption member. The absorbent member may be defined as a material that absorbs the exudate (EXD) generated in the affected area (W). For example, the absorbent member may include hydrocolloid or polyurethane.

In another embodiment, the absorbent layer 130 may further include a drug that aids wound healing. When the absorbent layer 130 is attached to the affected area (W), the drug may act on the affected area (W) to accelerate wound healing.

The release film 140 may be removed when the affected area treatment device 100 using an oxidation-reduction reaction is used, and may be disposed to cover the absorbent layer 130 . In order to prevent the absorbent layer 130 from being infected, the release film 140 may be attached to the upper surface of the absorbent layer 130 .

The wound treatment device 100 using the oxidation-reduction reaction according to the first embodiment of the present invention is electrically activated when attached to the affected area, and can quickly and safely restore the affected area. When the absorbent member absorbs the exudate, electrode materials having different polarities are electrically activated, and electrons are emitted to the affected area to generate current and form an electric field. The affected area can be quickly and safely recovered by electrical stimulation, and since the apparatus 100 for treating the affected area using an oxidation-reduction reaction maintains a wet state, scarring can be minimized.

The wound treatment device 100 using the oxidation-reduction reaction according to the first embodiment of the present invention generates electrical stimulation only when attached to the affected area, thereby ensuring the safety and predictability of the dressing device, and stably electrical stimulation. can be provided to the affected area.

3a and 3b are modified examples of the device for treating a damaged area using the oxidation-reduction reaction of FIG. 1 .

Referring to FIG. 3A , the electrode unit 120-1 of the affected area treatment device 100-1 using an oxidation-reduction reaction may be disposed to be exposed on the upper surface of the absorption layer 130. Compared to FIG. 2 , the first electrode pattern 121 - 1 and the second electrode pattern 122 - 1 may be disposed on the upper surface of the absorption layer 130 .

In one embodiment, the first electrode pattern 121-1 and the second electrode pattern 122-1 may be disposed to be recessed into the absorption layer 130 as shown in FIG. 3A. In another embodiment, the first electrode pattern 121 - 1 and the second electrode pattern 122 - 1 may be disposed to protrude from the absorption layer 130 .

In the affected area treatment device 100-1 using an oxidation-reduction reaction, since the first electrode pattern 121-1 and the second electrode pattern 121-2 are exposed to the outside, when attached to the affected area W, the electrode unit ( 120-1) can be quickly activated.

Referring to FIG. 3B , the electrode unit 120 - 2 of the affected area treatment device 100 - 2 using an oxidation-reduction reaction may be disposed to be included in the absorption layer 130 . Compared to FIG. 2 , the first electrode pattern 121 - 2 and the second electrode pattern 122 - 2 may be disposed in the inner space of the absorption layer 130 .

The affected area treatment device 100-2 using the oxidation-reduction reaction is stably supported because the first electrode pattern 121-2 and the second electrode pattern 122-2 are disposed inside the absorption layer 130, and the electrode Unit 120-2 can be quickly activated.

4a to 4e are other modified examples of the wound healing device using the oxidation-reduction reaction of FIG. 1 .

Referring to FIG. 4A , in the affected area treatment device 100A using an oxidation-reduction reaction, an electrode unit 120A may be disposed on the front surface of the absorption layer 130 . The first electrode pattern 121A and the second electrode pattern 122A each extend to a predetermined length and may be alternately disposed.

A plurality of first electrode patterns 121A and second electrode patterns 122A may be spaced apart from each other at predetermined intervals over the entire surface of the absorption layer 130 . In the affected area treatment device 100A using an oxidation-reduction reaction, since the first electrode pattern 121A and the second electrode pattern 122A are disposed over the entire surface of the absorption layer 130, a uniform current is generated over the entire area of the affected area. and a constant electric field can be formed in the affected area.

Referring to FIG. 4B , in the affected area treatment device 100B using an oxidation-reduction reaction, an electrode unit 120B may be disposed on the entire surface of the absorption layer 130 . The first electrode pattern 121B and the second electrode pattern 122B each have a predetermined size and may be alternately disposed.

The first electrode pattern 121B and the second electrode pattern 122B are provided in a dot shape, and a plurality of them may be disposed alternately and spaced apart from each other at predetermined intervals over the entire surface of the absorption layer 130 . In the affected area treatment device 100B using an oxidation-reduction reaction, since the first electrode pattern 121B and the second electrode pattern 122B are disposed over the entire surface of the absorption layer 130, a uniform current is generated over the entire area of the affected area. and a constant electric field can be formed in the affected area.

Referring to FIG. 4C , an apparatus for treating an affected area 100C using an oxidation-reduction reaction has a first electrode pattern 121C having a closed curve and a second electrode pattern 122C disposed within the first electrode pattern 121C. can The first electrode pattern 121C extends along the edge of the absorption layer 130 and may form a closed-loop. The second electrode pattern 122C is spaced apart from the first electrode pattern 121C, has a predetermined area, and may have a dot shape.

Referring to FIG. 4D , an apparatus for treating a wound using an oxidation-reduction reaction 100D has a first electrode pattern 121D having a closed curve and a second electrode pattern 122D disposed within the first electrode pattern 121D. can The first electrode pattern 121D extends along the edge of the absorption layer 130 and may form a closed circuit. The second electrode pattern 122D is spaced apart from the first electrode pattern 121D and may extend along the first electrode pattern 121D to a predetermined width and length.

Referring to FIG. 4E , the affected area treatment device 100E using an oxidation-reduction reaction includes a first electrode pattern 121E disposed on both sides and a second electrode pattern 122E disposed between the first electrode pattern 121E. ) can have. The first electrode pattern 121E may be disposed at the edge of the absorption layer 130 and the second electrode pattern 122E may be disposed at the center of the absorption layer 130 .

As shown in Figures 4c to 4e, the wound healing device using the oxidation-reduction reaction is spaced apart from the first electrode pattern and the second electrode pattern at the set position, and the direction of the current can be set to recover the wound in a preset direction. there is. This will be described in detail with reference to FIG. 16 below.

5 is a diagram showing a wound treatment device 200 using an oxidation-reduction reaction according to a second embodiment of the present invention, and FIG. 6 is a wound treatment device using an oxidation-reduction reaction of FIG. 5 attached to a wound ( 200).

Referring to FIGS. 5 and 6 , the apparatus 200 for treating an affected area using an oxidation-reduction reaction may include a base sheet 210 , an electrode unit 220 and an absorption layer 230 . Since the base sheet 210 and the electrode unit 220 are substantially the same as the base sheet 110 and the electrode unit 120 of the first embodiment, hereinafter, the absorption layer 230 will be mainly described.

The absorption layer 230 may be disposed to be spaced apart from the electrode unit 220 . It may be spaced apart from the first electrode pattern 221 and the second electrode pattern 222 . Referring to FIG. 6 , the edge of the absorption layer 230 may be spaced apart from the first electrode pattern 221 and the second electrode pattern 222 by a predetermined distance (G).

When the absorbent member absorbs the exudate EXD, the absorbent layer 230 expands and may extend to the first electrode pattern 221 and the second electrode pattern 222 . When the exudate is absorbed, the absorbing layer 230 forms an extended area EP in contact with the first electrode pattern 221 and the second electrode pattern 222 . The first electrode pattern 221 and the second electrode pattern 222 may be electrically activated by the extended area EP.

The extended region EP may be defined as a region in which the absorbent member of the absorbent layer 230 absorbs the exudate EXD and the area is enlarged. The first electrode pattern 221 and the second electrode pattern 222 may be connected to each other by including the first electrode pattern 221 and the second electrode pattern 222 inside the extended area EP.

In one embodiment, the absorbent layer 230 protrudes from the base sheet 210 to have a predetermined thickness, but may decrease in thickness while expanding when the exudate (EXD) is absorbed. That is, when the exudate EXD is absorbed, the absorbent member expands laterally, reducing the thickness of the absorbent layer 230 and creating the extended area EP.

The wound treatment device 200 using the oxidation-reduction reaction according to the second embodiment of the present invention is electrically activated when attached to the affected area, and can quickly and safely restore the affected area. When the absorbent member absorbs exudate or the like, the absorbent layer may be electrically activated while expanding. Since the electrode material can emit electrons and form an electric field in the affected area due to the expanded absorption layer, the affected area can be quickly and safely recovered by electrical stimulation. In addition, scarring can be minimized because the affected area treatment device 200 using an oxidation-reduction reaction covers the affected area and maintains a wet state.

The wound treatment device 200 using the oxidation-reduction reaction according to the second embodiment of the present invention generates electrical stimulation only when attached to the affected area, thereby securing the safety and predictability of the dressing device, and stably electrical stimulation. can be provided to the affected area.

7a and 7b are modified examples of the device for treating an affected area using the oxidation-reduction reaction of FIG. 5 .

Referring to FIG. 7A , in the affected area treatment device 200A using an oxidation-reduction reaction, the electrode unit 220A has a plurality of first electrode patterns 221A and second electrode patterns 222A, and each first electrode pattern An absorption layer 230A may be disposed between 221A and the second electrode pattern 222A.

The absorption layer 230A may be disposed to be spaced apart from the first electrode pattern 221A by the first gap g1 and spaced apart from the second electrode pattern 222A by the second gap g2. The first gap g1 and the second gap g2 may be set differently or the same.

The plurality of absorption layers 230A are spaced apart from each other by the electrode unit 220A, and may be integrally connected when absorbing the exudate EXD. As a result, electrical stimulation may be generated throughout the extended area EP.

Referring to FIG. 7B , the affected area treatment device 200B using an oxidation-reduction reaction includes a first electrode pattern 221B in which an electrode unit 220B has a closed curve and a first electrode pattern 221B disposed inside the first electrode pattern 221B. It may have a two-electrode pattern 222B.

The absorption layer 230 is disposed between the first electrode pattern 221 and the second electrode pattern 222, but not in contact with each other. When the absorbent member of the absorbent layer 230 absorbs the exudate EXD, the absorbent layer 230 expands to the extended region EP, and electrical stimulation may be formed in the extended region EP.

FIG. 8 is a view showing an apparatus 300 for treating a wound using an oxidation-reduction reaction according to a third embodiment of the present invention, and FIG. 9 is a cross-sectional view of the apparatus 300 for treating an affected area using an oxidation-reduction reaction of FIG. am.

Referring to FIGS. 8 and 9 , an apparatus for treating an affected area using an oxidation-reduction reaction 300 may include a base sheet 310 , an absorption unit 320 and a release film 330 . The base sheet 310 and the release film 330 are substantially the same as the base sheet 110 and the release film 140 of the first embodiment described above. Let's explain.

The absorption unit 320 is attached to the base sheet 310, and electrode materials in the form of particles are mixed with the absorption member AM. The absorption unit 320 may be formed in a layered structure on the base sheet 310 .

The absorption unit 320 is activated with different polarities and includes a first electrode material EL1 and a second electrode material EL2 having a particle shape. The first electrode material EL1 and the second electrode material EL2 have a particle shape and are disposed to be mixed in the absorbing member AM.

The absorption unit 320 is not electrically activated during storage, but when attached to the affected area W, the absorbent member AM absorbs the exudate EXD and electrically activates the electrode material so that electrons move or an electric field is formed. can

The first electrode material EL1 and the second electrode material EL2 are not limited to specific materials, and may be defined as materials capable of forming different electrodes by a potential difference. However, hereinafter, for convenience of description, a case in which the first electrode material EL1 is silver chloride (AgCl) and the second electrode material is zinc (Zn) will be mainly described. Accordingly, the first electrode material EL1 is set as a cathode electrode and the second electrode material EL2 is set as an anode electrode, and an oxidation-reduction reaction is generated as follows.

(cathode): AgCl _(s) + e ^- -> Ag (s) + Cl ^- _(aq)

(anode): Zn _(s) -> Zn ²⁺ _(S) + 2e ^-

The absorbent member AM may include hydrocolloid or polyurethane. However, hereinafter, an embodiment in which the absorbent member AM is a hydrocolloid will be mainly described.

In an exemplary embodiment, the absorption unit 320 mixes the first electrode material EL1 with the absorbent member AM, and mixes the second electrode material EL2 with another absorbent member AM, and mixes the two absorbents together. The first electrode material EL1 and the second electrode material EL2 may be mixed with the absorbent member AM by mixing the members AM with each other. In another embodiment, the absorption unit 320 may be formed by mixing the first electrode material EL1 with the absorption member AM and then adding the second electrode material EL2 thereto. Thereafter, the absorbent unit 320 may be attached to the base sheet 310 by laminating, screen printing, tape casting, or the like.

The affected area treatment device 300 using an oxidation-reduction reaction according to the third embodiment of the present invention is electrically activated when attached to the affected area, so that the affected area can be quickly and safely restored. When the absorbent member absorbs the exudate, the first electrode material and the second electrode material in the form of particles may be electrically activated. As a result, electrons are emitted to the affected area, an electric field is formed, the affected area can be quickly and safely recovered by electrical stimulation, and scarring can be minimized because the affected area treatment device 300 using the oxidation-reduction reaction maintains a wet state. can

The affected area treatment device 300 using the oxidation-reduction reaction according to the third embodiment of the present invention generates electrical stimulation only when attached to the affected area, thereby ensuring the safety and predictability of the dressing device, and stably electrical stimulation. can be given to the affected area.

In the affected area treatment device 300 using the oxidation-reduction reaction according to the third embodiment of the present invention, the particulate first electrode material and the second electrode material are randomly disposed, so that electrical activity can be increased. Since the first electrode material and the second electrode material in the form of particles are randomly disposed throughout the affected area, when the exudate is absorbed, the electrode materials react quickly to provide electrical stimulation to the affected area.

FIG. 10 is a diagram showing an apparatus 400 for treating an affected area using an oxidation-reduction reaction according to a fourth embodiment of the present invention.

Referring to FIG. 10 , an apparatus 400 for treating an affected area using an oxidation-reduction reaction may include a base sheet 410 and an absorption unit 420 . Since the base sheet 410 is substantially the same as the base sheet 110 of the first embodiment described above, hereinafter, for convenience of description, the absorption unit 420 will be mainly described.

The absorption unit 420 may include a first absorption layer 421 and a second absorption layer 422 . In the first absorption layer 421, the first electrode material EL1 in the form of particles is disposed on the absorption member AM, and the second absorption layer 422 includes the second electrode material EL2 in the form of particles on the absorption member AM. this is placed

The first absorbent layer 421 and the second absorbent layer 422 are disposed adjacent to the base sheet 410 and alternately disposed with each other. A second absorbing layer 422 may be disposed between the pair of first absorbing layers 421 , and the first absorbing layer 421 may be disposed between the pair of second absorbing layers 422 . In one embodiment, as shown in FIG. 10 , the first absorbing layer 421 and the second absorbing layer 422 may be disposed to contact each other. In another embodiment, the first absorbing layer 421 and the second absorbing layer 422 may be spaced apart from each other by a predetermined interval.

In the affected area treatment device 400 using the oxidation-reduction reaction according to the fourth embodiment of the present invention, when the exudate (EXD) is absorbed in the absorption unit 420, the first electrode material of the first absorption layer 421 and the second The second electrode material of the absorption layer 422 is electrically connected to form an electrical stimulus to the affected area (W).

FIG. 11 is a diagram showing an apparatus 500 for treating an affected area using an oxidation-reduction reaction according to a fifth embodiment of the present invention.

Referring to FIG. 11 , an apparatus for treating an affected area using an oxidation-reduction reaction 500 may include a base sheet 510 and an absorption unit 520 . Since the base sheet 510 is substantially the same as the base sheet 110 of the first embodiment described above, hereinafter, for convenience of description, the absorption unit 520 will be mainly described.

The absorption unit 520 may include a first absorption layer 521 , a second absorption layer 522 , and a third absorption layer 523 . In the first absorption layer 521, the absorption member AM is mixed with the first electrode material EL1 in the form of particles, and in the second absorption layer 522, the absorption member AM is mixed with the second electrode material EL2 in the form of particles. this is mixed

The third absorbing layer 523 is disposed between the first absorbing layer 521 and the second absorbing layer 522 . The third absorbing layer 523 includes only the absorbing member AM and does not include an electrode material. The third absorbing layer 523 may be formed of only the absorbing member AM to implement an electrical bridge function. When the exudate EXD is absorbed by the absorbent member AM, the first electrode material EL1 of the first absorbent layer 521 and the second electrode material EL2 of the second absorbent layer 522 are electrically connected to the affected area ( W) can be provided with electrons and electric fields.

In the affected area treatment device 500 using the oxidation-reduction reaction according to the fifth embodiment of the present invention, when the exudate (EXD) is absorbed in the absorption unit 520, the first electrode material EL1 of the first absorption layer 521 and the second electrode material EL2 of the second absorption layer 522 are electrically connected to form electrical stimulation on the affected area (W). The third absorbing layer 523 can electrically connect the first absorbing layer 521 and the second absorbing layer 522 quickly.

12 is a diagram showing an apparatus 600 for treating an affected area using an oxidation-reduction reaction according to a sixth embodiment of the present invention.

Referring to FIG. 12 , an apparatus 600 for treating an affected area using an oxidation-reduction reaction may include a base sheet 610 and an absorption unit 620 . Since the base sheet 610 is substantially the same as the base sheet 110 of the first embodiment described above, hereinafter, for convenience of description, the absorption unit 620 will be mainly described.

The absorption unit 620 includes a first absorption layer 621 and a second absorption layer 622, and the first absorption layer 621 and the second absorption layer 622 may be alternately disposed.

In the first absorption layer 621, the absorption member AM is mixed with the first electrode material EL1 in the form of particles, and in the second absorption layer 622, the absorption member AM is mixed with the second electrode material EL2 in the form of particles. this is mixed The first absorbent layer 621 and the second absorbent layer 622 are disposed adjacent to each other on the base sheet 610 and are alternately disposed.

In one embodiment, the first absorbing layer 621 and the second absorbing layer 622 may be spaced apart from each other at a predetermined interval as shown in FIG. 12 . In another embodiment, the first absorbing layer 621 and the second absorbing layer 622 may be disposed to contact each other.

When the affected area treatment device 600 using an oxidation-reduction reaction is attached to the affected area W, the exudate EXD is absorbed into the first absorption layer 621 and the second absorption layer 622, and the first absorption layer 621 and The second absorption layer 622 is electrically active by being connected to each other.

In another embodiment, in the absorption unit 620, a plurality of absorption layers may be alternately disposed, and the first electrode material and the second electrode material in the form of particles may be mixed in each absorption layer.

In another embodiment, in the absorption unit 620, a plurality of absorption layers are alternately disposed, the specific gravity of the first electrode material in the first absorption layer is greater than that of the second electrode material, and the specific gravity of the second electrode material in the second absorption layer. The specific gravity may be greater than that of the first electrode material. When the absorption unit is attached to the affected area, first, each absorption layer is electrically connected, and then adjacent absorption layers are electrically connected to each other to continuously provide electrical stimulation to the affected area.

FIG. 13 is a view showing an apparatus 700 for treating an affected area using an oxidation-reduction reaction according to a seventh embodiment of the present invention.

Referring to FIG. 13 , an apparatus for treating an affected area using an oxidation-reduction reaction 700 may include a base sheet 710 and an absorption unit 720 . Since the base sheet 710 is substantially the same as the base sheet 110 of the first embodiment described above, hereinafter, for convenience of description, the absorption unit 720 will be mainly described.

The absorption unit 720 includes a first absorption layer 721 and a second absorption layer 722, and the first absorption layer 721 and the second absorption layer 722 may be alternately stacked. In the first absorption layer 721, the absorption member AM is mixed with the first electrode material EL1 in the form of particles, and in the second absorption layer 722, the absorption member AM is mixed with the second electrode material EL2 in the form of particles. this is mixed

The first absorption layer 721 and the second absorption layer 722 may be alternately stacked on one surface of the base sheet 710 . 13 shows that the first absorption layer 721 and the second absorption layer 722 are stacked one by one, but is not limited thereto and may have a multilayer structure.

In the affected area treatment device 700 using an oxidation-reduction reaction according to the seventh embodiment of the present invention, when the exudate (EXD) is absorbed in the absorption unit 720, the first electrode material EL1 of the first absorption layer 721 and the second electrode material EL2 of the second absorption layer 722 are electrically connected to form an electrical stimulus to the affected area (W).

Since the exudate (EXD) must be absorbed in both the first and second absorption layers 721 and 722, which are stacked, after attaching the affected area treatment device 700 using an oxidation-reduction reaction to the affected area W, a predetermined It becomes electrically active after a period of time. Accordingly, the apparatus 700 for treating the affected area using the oxidation-reduction reaction can effectively provide electrical stimulation to the affected area where electrical stimulation is to be provided after a predetermined period of time continues.

14 is a diagram showing an apparatus 800 for treating a wound using an oxidation-reduction reaction according to an eighth embodiment of the present invention.

Referring to FIG. 14 , an apparatus 800 for treating an affected area using an oxidation-reduction reaction may include a base sheet 810 , a first electrode pattern 820 and an absorption unit 830 . Since the base sheet 810 is substantially the same as the base sheet 110 of the first embodiment described above, hereinafter, for convenience of description, the first electrode pattern 820 and the absorption unit 830 will be mainly described. .

The first electrode pattern 820 and the absorption unit 830 may each include electrode materials having different polarities. The first electrode pattern 820 is disposed on one side of the base sheet 810 and may include the first electrode material EL1. The absorption unit 830 is disposed on the base sheet 810 and includes a second electrode material EL2 having a different polarity from the first electrode material EL1, but the second electrode material in the form of particles is attached to the absorption member AM. (EL2) may be arranged to be mixed.

The absorption unit 830 is disposed to cover the first electrode pattern 820, and when the exudate EXD is absorbed by the absorption member AM, the first electrode material EL1 and the second electrode material EL2 are electrically electrically connected. can be activated with

The first electrode material and the second electrode material are not limited to specific materials, and may be defined as materials capable of forming different electrodes by a potential difference. However, hereinafter, for convenience of description, a case in which the first electrode material EL1 is silver chloride (AgCl) and the second electrode material is zinc (Zn) will be mainly described. The first electrode material EL1 is a cathode electrode, and the second electrode material EL2 is an anode electrode, and an oxidation-reduction reaction is generated as follows.

(cathode): AgCl _(s) + e ^- -> Ag (s) + Cl ^- _(aq)

(anode): Zn _(s) -> Zn ²⁺ _(S) + 2e ^-

When the affected area treatment device 800 using an oxidation-reduction reaction is attached to the affected area W, the exudate EXD is absorbed by the absorbent member AM, and the first electrode material EL1 of the first electrode pattern 820 and the particle-type second electrode material EL2 are electrically activated. The affected area treatment device 800 using the oxidation-reduction reaction can provide electrical stimulation to the affected area because a current and an electric field are formed by the generated electrons.

The affected area treatment device 800 using an oxidation-reduction reaction according to the eighth embodiment of the present invention is electrically activated when attached to the affected area, so that the affected area can be quickly and safely restored. When the absorbent member absorbs the exudate, the first electrode material and the second electrode material in the form of particles may be electrically activated. As a result, electrons are emitted to the affected area, an electric field is formed, the affected area can be quickly and safely recovered by electrical stimulation, and scarring can be minimized because the affected area treatment device 800 using the oxidation-reduction reaction maintains a wet state. can

The affected area treatment device 800 using the oxidation-reduction reaction according to the eighth embodiment of the present invention generates electrical stimulation only when attached to the affected area, so that the safety and predictability of the dressing device can be secured, and electrical stimulation is stably performed. can be given to the affected area.

In the affected area treatment device 800 using the oxidation-reduction reaction according to the eighth embodiment of the present invention, electrode materials in the form of particles are randomly arranged, so that electrical activity can be increased. The position of the first electrode material is fixed in a predetermined pattern, and the second electrode material in the form of particles is randomly disposed throughout the affected area. When the exudate is absorbed by the absorbent member, each electrode material is quickly activated to provide electrical stimulation to the affected area, thereby effectively treating the wound.

15a to 15d are modified examples of the device for treating an affected area using the oxidation-reduction reaction of FIG. 14 .

Referring to FIG. 15A , an apparatus for treating an affected area 800A using an oxidation-reduction reaction may include a base sheet 810, a first electrode pattern 820A, and an absorption unit 830A. Compared to the eighth embodiment described above, in the affected area treatment device 800A using the oxidation-reduction reaction, the first electrode pattern 820A is disposed above the absorption unit 830A, so that exudate is removed from the first electrode pattern 820A. ), electrical activity can be rapidly generated.

As another modification, the first electrode pattern 820A may be disposed to be recessed in the absorption unit 830A or disposed inside the absorption unit 830A.

Referring to FIG. 15B , an apparatus for treating an affected area 800B using an oxidation-reduction reaction may include a base sheet 810, a first electrode pattern 820B, and an absorption unit 830B. The absorption unit 830B is disposed between the first electrode patterns 820B and spaced apart so as not to contact the first electrode patterns 820B. When the absorbent member AM absorbs the exudate EXD, the absorbent member AM expands to form an extended area EP. As a result, the first electrode material and the second electrode material are electrically connected to each other, so that electrical stimulation can be provided to the affected area.

Referring to FIG. 15C , an apparatus for treating an affected area 800C using an oxidation-reduction reaction may include a base sheet 810, an electrode unit 820C, and an absorption unit 830C. The electrode unit 820C may have a first electrode pattern 821C and a second electrode pattern 822C having different polarities, and are spaced apart from each other.

In the absorption unit 830C, the first electrode material EL1 may be mixed with the absorption member AM as shown in FIG. 15C. In another embodiment, the second electrode material EL2 may be mixed (not shown) with the absorbing member AM. While the absorbent member AM absorbs the exudate EXD, the first electrode material EL1 or the second electrode material EL2 of the absorbent member electrically connects the electrode unit 820C to provide electrical stimulation to the affected area. can do.

In another modification, the absorption unit 830C is disposed between the first electrode pattern 821C and the second electrode pattern 822C, but not in contact with the first electrode pattern 821C and the second electrode pattern 822C. can be placed. When the absorbing member AM absorbs the exudate EXD, the first electrode pattern 821C and the second electrode pattern 822C may be electrically activated while the absorbing unit 830C expands.

Referring to FIG. 15D , an apparatus for treating an affected area 800D using an oxidation-reduction reaction may include a base sheet 810, an electrode unit 820D, and an absorption unit 830D. The electrode unit 820D may have a first electrode pattern 821D and a second electrode pattern 822D having different polarities, and are spaced apart from each other.

In the absorption unit 830D, the first electrode material EL1 and the second electrode material EL2 are mixed with the absorption member AM. When the absorbent member AM absorbs the exudate EXD, the first electrode material EL1 and the second electrode material EL2 in the form of particles in the absorbent unit 830D may be electrically activated. At the same time, the absorption unit 830D may electrically activate the first electrode pattern 821D and the second electrode pattern 822D of the electrode unit 820D. That is, firstly, the absorption unit 830D is electrically activated, and secondarily, the electrode unit 820D is electrically activated to amplify the strength of the electrical stimulation and sustain the electrical stimulation.

As another modification, the absorption unit 830D includes a particle-shaped first electrode material EL1 and a particle-shaped second electrode material EL2, wherein the particle-shaped first electrode material EL1 is used as the second electrode material. Disposed adjacent to the pattern 822D, the particle-shaped second electrode material EL2 may be disposed adjacent to the first electrode pattern 821D.

In detail, the ratio of the first electrode material EL1 per unit volume in the absorption unit 830D increases as it approaches the second electrode pattern 822D, and the ratio of the second electrode material EL2 per unit volume in the absorption unit 830D. may increase as it is closer to the first electrode pattern 821D.

Among the absorption units 830D, a plurality of first electrode materials EL1 are disposed adjacent to the second electrode pattern 822D, so that electrical activity is amplified in the second electrode pattern 822D. In addition, a plurality of second electrode materials EL2 of the absorption unit 830D may be disposed adjacent to the first electrode pattern 821D, so that electrical activity may be amplified in the first electrode pattern 821D.

16 is a view showing a method of treating a wound using an oxidation-reduction reaction according to another embodiment of the present invention.

Referring to FIG. 16 , using the apparatus for treating a wound using an oxidation-reduction reaction of the present application, wound healing can be controlled according to the arrangement of electrodes.

As in the wound treatment devices 100C and 100D using the oxidation-reduction reaction of FIG. 4C or 4D, when the first electrode pattern has a closed curve and the second electrode pattern is disposed inside the first electrode pattern, recovery of the affected area is progressed toward the second electrode pattern. Thus, the wound is healed towards one point.

When the second electrode pattern is disposed between the first electrode patterns on both sides, as in the apparatus 100E for treating the affected area using the oxidation-reduction reaction of FIG. 4E , the recovery of the affected area proceeds toward the second electrode pattern. Thus, the wound is healed in the longitudinal direction of the second electrode.

Considering the treatment direction of the affected area as described above, a method of treating the affected area using an oxidation-reduction reaction may be set.

First, the shape of the affected part of the object is confirmed. Depending on the shape of the affected area, it can be considered whether the scar of the wound will be formed as a point or a straight line.

Then, considering the edge of the affected area, a device for treating the affected area using an oxidation-reduction reaction is selected and attached to the affected area. For example, if the affected part is a face and the scar should be minimized or if the affected part is circular, a device having a second electrode pattern disposed inside the first electrode pattern of the closed curve is attached to the affected part as shown in FIG. 4c or 4d, and the second electrode pattern You can set the direction of recovery so that the affected area can be restored. In addition, if the affected area is formed long in one direction, a second electrode pattern may be disposed between the pair of first electrode patterns as shown in FIG. 4E so that the affected area recovers toward the second electrode pattern.

An apparatus and method for treating a diseased area using an oxidation-reduction reaction may determine a recovery direction of a diseased area by adjusting the arrangement of electrode units and electrode units. Since the direction of the generated electric field affects the growth of fibroblasts, the direction of wound closure can be set by adjusting the arrangement of electrode units and electrode units.

17 is a photograph comparing the treatment effect using the device for treating an affected area using an oxidation-reduction reaction according to the present invention.

Referring to FIG. 17, 8 affected areas are set in the subject and the recovery rate of wounds for 7 days is shown.

It is a comparative example in which wounds were treated with a dressing band without applying an electric field to the four affected areas on the left. The wounds were treated by attaching the device of any one of Examples 1 to 8 to the 4 affected areas on the right side. When an electric field is applied to the affected area, it can be confirmed that the recovery speed of the wound is increased and the wound can be recovered cleanly.

In this way, the present invention has been described with reference to the embodiments shown in the drawings, but this is only exemplary, and those skilled in the art will understand that various modifications and equivalent other embodiments are possible therefrom. . Therefore, the true technical scope of protection of the present invention should be determined by the technical spirit of the appended claims.

100, 200, 300, 400, 500, 600, 700, 800: Apparatus for wound treatment using oxidation-reduction reaction

Claims (18)

base sheet;
an electrode unit attached to the base sheet and having electrode materials having different polarities; and
An absorption layer attached to the base sheet and activating the electrode material to be electrically connected by the absorbed exudate;
An apparatus for treating a wound using an oxidation-reduction reaction, wherein the absorption layer is disposed so as to cover the electrode unit and not be exposed to the outside. According to claim 1,
The electrode unit
A first electrode pattern provided with at least one or more and disposed on one side of the base sheet; and
A wound treatment device using an oxidation-reduction reaction having a; second electrode pattern provided with at least one and disposed spaced apart from the first electrode pattern. According to claim 1,
The electrode unit
a first electrode pattern forming a closed curve along the base sheet; and
A second electrode pattern disposed inside the first electrode pattern; having a, oxidation-reduction reaction using the affected area treatment device. delete According to claim 1,
the absorbent layer
An apparatus for treating an affected area using an oxidation-reduction reaction comprising a hydrocolloid or polyurethane. base sheet; and
An absorption unit attached to the base sheet, mixing an electrode material in the form of particles with an absorbent member, and activating the electrode material when the exudate is absorbed into the absorbent member;
the absorption unit
A wound treatment device using an oxidation-reduction reaction, wherein a first electrode material and a second electrode material activated with different polarities are randomly disposed inside the absorbent member. delete delete delete delete delete According to claim 6,
the absorbent material
An apparatus for treating an affected area using an oxidation-reduction reaction comprising a hydrocolloid or polyurethane. base sheet;
a first electrode pattern formed of a first electrode material disposed on the base sheet; and
An absorption unit disposed on the base sheet and having an absorption member having a polarity different from that of the first electrode material but in which a particulate second electrode material is mixed,
the absorption unit
It is disposed spaced apart from the first electrode pattern, and when activated, expands to contact the first electrode pattern, a wound treatment device using an oxidation-reduction reaction. According to claim 13,
the absorption unit
When the exudate is absorbed by the absorbent member, the first electrode material and the second electrode material are electrically connected to the affected area treatment device using an oxidation-reduction reaction. delete According to claim 13,
A second electrode pattern disposed spaced apart from the first electrode pattern and formed of the second electrode material; and
the absorption unit
Located between the first electrode pattern and the second electrode pattern,
When the absorption unit is activated and one end contacts the first electrode pattern, the other end of the absorption unit extends to contact the second electrode pattern. According to claim 13,
the absorption unit
An apparatus for treating an affected area using an oxidation-reduction reaction, further comprising the first electrode material in the form of particles mixed with the absorbent member. According to claim 13,
the absorbent material
An apparatus for treating an affected area using an oxidation-reduction reaction comprising a hydrocolloid or polyurethane.

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