KR102570162B1 - Smart bandage for wound care - Google Patents

Abstract

A smart band for treating wounds is provided. The smart band may include a communication module capable of communicating with an electronic device and including a wireless power transmission function; and a band module attachable to a user's body part. The communication module may include an antenna and an integrated circuit receiving data and power from the electronic device; one or more LDO regulators supplying power to the band module; and an MCU controlling the at least one LDO regulator, wherein the band module includes: a time-limiting biomimetic material electrode supplying power from the at least one LDO regulator to a time-limiting biomimetic material pattern; the time-limiting biomimetic material pattern that electrically stimulates the wound by being in contact with the wound of the user's body; and a band providing adhesive force so that the time-limited biomimetic material electrode and the time-limited biomimetic material pattern can be attached to the user's body.

Description

Smart band for wound treatment {SMART BANDAGE FOR WOUND CARE}

The present disclosure relates to a smart band for wound treatment that accelerates the wound healing rate by applying electrical stimulation to the wound, applies the optimal wound treatment method according to the degree of wound and the user, and protects the wound from the outside. will be.

In wound treatment, a method of applying electrical stimulation is used. Microscopic electrical stimulation accelerates the ability of fibroblasts to proliferate and differentiate, thereby accelerating wound resilience.

The problem in treatment using electrical stimulation is that when accelerating using external stimulation to give electrical stimulation to the wound, the external resistance of various liquid chemicals generated in the wound or the size of bioresistance according to fibrin is different, Variation is also uneven, so it's hard to see a big effect. Therefore, the method of directly stimulating the inside of the wound through electrodes is most effective, but the method of directly stimulating the inside of the wound electrically requires a surgical operation, etc., and thus is less effective.

In wound treatment, there is a need for a product capable of efficiently recovering a wound while directly applying electrical stimulation to the inside of the wound without a surgical operation.

Registered Patent Publication No. 10-1790081 (2017.10.26.)

The disclosed embodiments allow a user to be provided with a smart band for wound treatment that allows a user to quickly recover a wound with a high degree of restoration.

The problems to be solved by the present disclosure are not limited to the problems mentioned above, and other problems not mentioned will be clearly understood by those skilled in the art from the description below.

According to one aspect of the present disclosure, a smart band for wound healing may be provided. The smart band for wound treatment includes a communication module capable of communicating with an electronic device and including a wireless power transmission function; and a band module attachable to a user's body part. The communication module may include an antenna and an integrated circuit receiving data and power from the electronic device; one or more LDO regulators supplying power to the band module; and an MCU controlling the at least one LDO regulator, wherein the band module includes: a time-limiting biomimetic material electrode supplying power from the at least one LDO regulator to a time-limiting biomimetic material pattern; the time-limiting biomimetic material pattern that electrically stimulates the wound by being in contact with the wound of the user's body; and a band providing adhesive force so that the time-limited biomimetic material electrode and the time-limited biomimetic material pattern can be attached to the user's body.

The band module further includes a hydrogel/hydrocolloid layer attached to a first surface of the layer including the time-limiting biomimetic material pattern, and a second surface of the layer including the time-limiting biomimetic material pattern. It may be in contact with the wound.

In the band module, the first surface of the layer including the time-limiting biomimetic material electrode is attached to the hydrogel/hydrocolloid layer, and polyurethane is attached to the second surface of the layer including the time-limiting biomimetic material electrode. A film layer may be attached, and a part of the time-limiting biomimetic material electrode may be inserted into a part of the hydrogel/hydrocolloid layer to supply electric power to the time-limiting biomimetic material pattern.

The smart band may further include a biomimetic material electrode link for providing an electrical connection between the communication module and the band module.

The time-limited biomimetic material constituting the time-limited biomimetic material pattern, the time-limited biomimetic material electrode, and the time-limited biomimetic material electrode link are materials capable of electrical conduction and capable of being degraded over time and bioabsorbed. It may consist of

In the smart band, the time-limited biomimetic material pattern, the time-limited biomimetic material electrode, and the time-limited biomimetic material electrode link have different decomposition rates. The time-limited biomimetic material of each material electrode link is constituted, and the order of the decomposition rate of the time-limited biomimetic material is the time-limited biomimetic material pattern, the time-limited biomimetic material electrode, and the time-limited biomimetic material. It may be the order of the mimic material electrode link.

The one or more LDO regulators may include a first LDO regulator, a second LDO regulator, and a third LDO regulator, and the first LDO regulator, the second LDO regulator, and the third LDO regulator may have different specifications.

The communication module receives at least one of wound information and user information from the electronic device, and the MCU, based on at least one of the wound information and user information, the first LDO regulator, the second LDO regulator and Electrical stimulation of the time-limited biomimetic material pattern may be adjusted by controlling at least one of the third LDO regulators.

The wound information may include at least one of a wound size and a wound severity, and the user information may include at least one of gender, age, disease, and obesity.

The thickness of the time-limited biomimetic material pattern is 1 μm or more and 25 μm or less, the thickness of the time-limited biomimetic material electrode is 30 μm or more and 60 μm or less, and the thickness of the time-limited biomimetic material electrode link is 50 μm or more It may be 75 μm or less.

According to the smart band for wound treatment of the present disclosure, first, through electrical stimulation, the electric resistance of the wound is lowered by lowering the potential of the cell according to the transmission of the action mechanism of the wound having high resistance, and the electrical signal is maintained to transmit the signal between cells. This makes rapid treatment possible by accelerating the proliferation and migration of cells.

Second, the thermal energy generated by electrical treatment accelerates the melting rate of gelatin and hydrogel included in the smart band for wound treatment, and further accelerates these materials and fibroblasts of granulation tissue to form collagen. Substitution and cross-linking accelerate rapid differentiation and growth.

Third, when the mixture is used on the electrode, it is possible to control the speed of vaporization according to the electric stimulation of the ooze, and by trapping the wound healing material in the mixture, the speed of hemostasis is maximized and the inflammatory reaction step is reduced, while blood vessel formation and fibroblast proliferation can proceed simultaneously. That is, it is possible to minimize an inflammatory phase and accelerate a proliferative phase and a remodeling phase.

Fourth, there is an advantage in that it is possible to optimize the wet condition by vaporizing the problem of delayed recovery due to the wet condition in the treatment of hydrocolloids and long-term wounds with electrical stimulation.

1 is a diagram showing a smart band system for wound healing according to an embodiment of the present disclosure.
2 is a diagram illustrating a smart band for wound healing according to an embodiment of the present disclosure.
3 is a block diagram showing the configuration of a communication module of a smart band for wound healing according to an embodiment of the present disclosure.
4 is a flowchart illustrating an operation of controlling electrical stimulation by a smart band for wound healing according to an embodiment of the present disclosure.
5 is a cross-sectional view of a band module of a smart band for wound healing according to an embodiment of the present disclosure.
6 is a diagram for explaining a wound treatment process by a smart band for wound treatment according to an embodiment of the present disclosure.
Figure 7 is a graph for explaining the test results of the current transmission rate of the wound treatment band according to an embodiment of the present disclosure.
8 is a graph for explaining a wound healing effect test result of a band for wound healing according to an embodiment of the present disclosure.

Like reference numbers designate like elements throughout this disclosure. The present disclosure does not describe all elements of the embodiments, and general content or overlapping content between the embodiments in the technical field to which the present disclosure belongs is omitted. The term module used in the specification may be implemented in hardware, and according to embodiments, a plurality of modules may be implemented as one component, or one module may include a plurality of components.

Throughout the specification, when a part is said to be "connected" to another part, this includes not only the case of being directly connected but also the case of being indirectly connected, and indirect connection includes being connected through a wireless communication network. do.

In addition, when a certain component is said to "include", this means that it may further include other components without excluding other components unless otherwise stated.

Terms such as first and second are used to distinguish one component from another, and the components are not limited by the aforementioned terms.

Expressions in the singular number include plural expressions unless the context clearly dictates otherwise.

In each step, the identification code is used for convenience of description, and the identification code does not explain the order of each step, and each step may be performed in a different order from the specified order unless a specific order is clearly described in context. there is.

Hereinafter, the working principle and embodiments of the present disclosure will be described with reference to the accompanying drawings.

1 is a diagram showing a smart band system for wound healing according to an embodiment of the present disclosure.

Referring to FIG. 1 , a smart band system according to an embodiment includes an electronic device 110 and a smart band 120 for wound healing. The smart band 120 for wound treatment is connected to the electronic device 110 so as to be communicable. The electronic device 110 may include all types of electronic devices that provide short-range communication (eg, NFC, etc.) and wireless power transfer functions. For example, the electronic device 110 may include a smart phone, tablet PC, smart watch, smart wristband, etc., but is not limited thereto.

In one embodiment, the smart band 120 for wound treatment is used by being attached to a wound. In general, when a wound is healed, nerves and cells try to repair the original wound according to an electrical phenomenon called action current. , plays a role in synthesizing and restoring tissue components such as collagen in cells. In this case, fine electrical stimulation can accelerate the resilience by accelerating the proliferation and differentiation ability of fibroblasts.

The problem here is that acceleration through external stimulation for electrical stimulation to the wound is difficult to see the effect because the external resistance of various liquid chemicals generated in the wound or the size / variation of bioresistance according to fibrin is uneven. will be. Therefore, the method of directly stimulating the inside of the wound through electrodes is the most effective, but the method of directly stimulating the inside of the wound electrically requires a surgical operation after all, and thus is less effective. For this problem, a method of treating with a machine that reduces bioresistance deviation by discharging exudate through a wound dressing-based negative pressure device and smoothes blood flow while lowering bioresistance by facilitating blood flow is used, but this method is natural It is close to treatment and has low efficiency compared to electrical stimulation method. Therefore, biomedical engineers have continued to study how to speed up the dermal layer with electricity using biomaterials having conductivity in a way that minimizes wound irritation that is not subject to external resistance to liquid chemicals without surgical operation.

The smart band 120 for wound treatment according to the present disclosure may include a biomimetic material with a limited time limit. The time-limiting biomimetic material may operate temporarily to provide electrical stimulation to the wound, and may be absorbed into the living body during wound healing.

In one embodiment, when the user attaches the smart band 120 for wound treatment to a wound, a part of the time-limited biomimetic material included in the smart band 120 for wound treatment is inserted into the wound to generate electrical stimulation inside the wound. can provide

Biomimetic materials are, for example, nanomolybdenum (Mo), molybdenum disulfide (MoS ₂ ), tungsten disulfide (WS ₂ ), zinc oxide (ZnO), magnesium oxide (MgO), etc. A material without the may be used, but is not limited thereto. When electricity is supplied to a biomimetic material, that is, a material that is harmless to the human body capable of electrical conduction and electrically stimulates the wound, fibroblasts rapidly proliferate and differentiate to quickly restore the dermis, and the wound is healed. Healed.

However, although the recovery of the dermis is accelerated by electrical stimulation through this method, the recovery tension drops to 80% compared to the previous wound, and it can be freed from the existing wound skin (a skin formed by drying blood, pus, ooze, etc.) There is a problem that there is no problem, and a problem that the exudate of the wound is quickly vaporized. In other words, in the mucus, macrophages that remove foreign substances such as dead cells and bacteria, leukocytes and lysosomal enzymes that promote wound healing, and growth factors are concentrated. This can be.

The smart band 120 for wound treatment according to the present disclosure is designed to restore the dermis by providing electrical stimulation inside the wound through a wound insert-type material, and at the same time to create a moist environment without vaporizing components such as ooze, so that the wound It can provide an experience of improving resilience and speed of wound healing.

Hereinafter, referring to the following drawings and corresponding descriptions, operations of the smart band 120 for wound treatment and the electronic device 110 will be understood in more detail.

2 is a diagram illustrating a smart band for wound healing according to an embodiment of the present disclosure.

Referring to FIG. 2 , a smart band 120 for wound treatment according to an embodiment may include a communication module 210 and a band module 220 .

In one embodiment, the communication module 210 may control power supplied to the band module 220 and transmit electrical stimulation to control a use time for wound healing. The communication module 210 may receive power through an electronic device 110 (eg, a smart phone, a smart watch, etc.) providing an NFC function, and may be used to control a wound healing operation from the electronic device 110. Necessary information (eg, wound information, user information, etc.) may be received. Wound information received from the electronic device 110 to the smart band 120 for wound treatment may include at least one of the size and degree of the wound, but is not limited thereto. In addition, user information received from the electronic device 110 to the smart band 120 for wound treatment may include at least one of gender, age, disease, and obesity, but is not limited thereto.

The communication module 210 may include an antenna, an MCU, a communication integrated circuit (eg, an NFC integrated circuit for short-range wireless communication, and an LDO regulator. In addition, the communication module 210 may include wireless power for wireless power transmission. It may also include a transmission integrated circuit (Qi (qi) integrated circuit for wireless power transmission, etc.). A description of each component included in the communication module 210 is further described with reference to FIG. do.

In one embodiment, the band module 220 may include an adhesive member to be attached to a user's body part. The adhesive member may be, for example, a polyurethane film, but is not limited thereto. Band module 220 may include a material for wound healing that can improve the recovery rate of the wound by transmitting electrical stimulation to the wound. The material for wound healing may be composed of a material that operates temporarily as a time-limited material, and may be composed of a biomimetic material that can be absorbed by the living body in the course of wound healing.

The band module 220 may include a time-limiting biomimetic material electrode, a time-limiting biomimetic material pattern, a hydrogel layer, or a hydrocolloid layer. A description of each component included in the band module 220 will be further described with reference to FIG. 5 .

The communication module 210 and the band module 220 may be physically connected through an electrode link made of a time-limiting biomimetic material.

3 is a block diagram showing the configuration of a communication module of a smart band for wound healing according to an embodiment of the present disclosure.

The communication module 210 of the smart band for wound treatment 120 according to an embodiment may include one or more circuit elements enabling the communication function and the wireless power transmission function to be performed. In describing FIG. 3 , an example in which the communication module 210 of the smart band 120 is implemented using NFC technology will be described. However, this is only an example for convenience of description. That is, it should be understood that the communication module 210 capable of performing the communication function and the wireless power transmission function can employ other various types of circuit elements apart from the example of FIG. 3 by a design change by a person skilled in the art. something to do. For example, the communication module 210 may be implemented as an active RFID capable of wireless power transmission and communication. Alternatively, the communication module 210 may employ wireless communication technologies of various standards such as a Bluetooth module and a Wi-Fi module, and various types of wireless communication technologies such as Qi, AirFuel, WiTricity, and Power Matters Alliance (PMA). A standard wireless power transmission technology may be employed.

Referring back to Figure 3, an example for using the wireless communication and wireless power transmission technology of the smart band 120 for wound healing will be described as an NFC module.

Referring to FIG. 3, the communication module 210 of the smart band 120 for wound treatment includes an antenna 310, an NFC integrated circuit 320, an MCU 330, a first LDO regulator 340, and a second LDO. A regulator 350 and a third LDO regulator 360 may be included.

The communication module 210 may wirelessly receive radio waves from the electronic device 110 using the antenna 310 . The antenna 310 may be an antenna for receiving a signal of 13.56 MHz, which is an NFC standard frequency, and may be manufactured in the form of an F-PCB. The antenna 310 may induce power using energy supplied by an electromagnetic field or the like. For example, the communication module 210 may receive a voltage of 2.4V to 5.5V and a current of up to 300mA based on energy supplied from the electronic device 110 .

The NFC integrated circuit 320 may supply power necessary for the operation of the MCU and power necessary for the operation of the first LDO regulator 340 to the third LDO regulator 360 . The MCU may determine which LDO regulator among the first LDO regulator 340 to the third LDO regulator 360 is to be used, and supply power required for operation of the determined LDO regulator.

The first LDO regulator 340 to the third LDO regulator 360 supply power to the band module 220, and the band module 220 includes a time-limited biomimetic material pattern 370 to the wound site. By delivering electrical stimulation, the wound can be healed.

The first LDO regulator 340 to the third LDO regulator 360 may each have different specifications. For example, each of the first LDO regulator 340, the second LDO regulator 350, and the third LDO regulator 350 may be responsible for different loads (load currents). The MCU 330 may use any one of the first LDO regulator 340, the second LDO regulator 350, and the third LDO regulator 350, or the first LDO regulator 340 to provide appropriate wound healing. , two or more of the second LDO regulator 350 and the third LDO regulator 360 may be used.

In one embodiment, the communication module 210 may receive one or more information including wound information, user information, operation time and treatment time of the smart band 120 for wound treatment, or a combination thereof. Based on the received information, the smart band 120 for wound treatment controls the operation time / treatment time of applying electrical stimulation based on the MCU's Real Time Clock (RTC) or an external RTC, and the first LDO regulator 340 , the second LDO regulator 350 and the third LDO regulator 360, by controlling the time, voltage, and current for wound healing, the electrical stimulation degree / time of the time-limited biomimetic material pattern 370 can be adjusted.

On the other hand, the smart band 120 for wound treatment of the present disclosure has been described as using three LDO regulators, but the design change of the smart band 120 for wound treatment (eg, the size of the smart band 120 for wound treatment) change), in some embodiments, the number of LDO regulators may be changed. For example, the number of LDO regulators may be 1 to 5, but is not limited thereto.

4 is a flowchart illustrating an operation of controlling electrical stimulation by a smart band for wound healing according to an embodiment of the present disclosure.

Referring to FIG. 4 , in step S410, the smart band 120 for wound treatment may receive at least one of wound information and user information from the electronic device 110. A user may input at least one of wound information and user information using the electronic device 110 . For example, the user may input at least one of wound information and user information through an application installed in the electronic device 110 or web access. In this case, the wound information may include at least one of the size and degree of the wound, and the user information may include at least one of gender, age, disease, and degree of obesity.

In step S420, the smart band 120 for wound treatment is used in the first LDO regulator 340, the second LDO regulator 350, and the third LDO regulator 360 based on at least one of wound information and user information. LDO regulator can be determined.

In one embodiment, the degree of electrical stimulation required for wound treatment may be different according to various factors such as the size or degree of the wound. For example, the larger the wound, the lower the resistance value, and since the resistance increases as the wound heals, the degree of electrical stimulation to be supplied may be different depending on the size and degree of the wound. Therefore, the smart band 120 for wound treatment is any one of the first LDO regulator 340, the second LDO regulator 350, and the third LDO regulator 360 or the first LDO regulator 340 based on the wound information. , the second LDO regulator 350 and the third LDO regulator 360 may be used.

In one embodiment, the degree of electrical stimulation required for wound healing may be different according to the user's body information. For example, the body at the age of newborn has a high bioelectrical potential of 5-6V, but the bioelectrical potential decreases to 3V from the age of 30, and the bioelectrical potential decreases to 3V when entering the old age of the age of 60s. is lowered to 2V. However, as age increases, resistance to wounds (impedance) increases rapidly. Therefore, the degree of electrical stimulation to be supplied to the wound may be different according to the user's age. In addition, the higher the age and the degree of obesity, the higher the voltage applied to the wound, and the higher the output of the current provided. Therefore, the smart band 120 for wound treatment is based on user information, the first LDO regulator 340, the second LDO regulator 350, the third LDO regulator 360 or any one of the first LDO regulator 340 , the second LDO regulator 350 and the third LDO regulator 360 may be used.

In step S430, the smart band for wound healing 120 may supply power to the band module 220 by controlling the determined LDO regulator.

In one embodiment, the smart band 120 for wound treatment is capable of power output of 10 to 250uW. The smart band 120 for wound treatment may allow power to be supplied to the band module 220 through the determined LDO regulator. For example, the smart band 120 for wound treatment may be supplied with power to the band module 220 using the first LDO regulator 340 and the second LDO regulator 350 .

In one embodiment, the smart band 120 for wound treatment may dynamically vary the degree of electrical stimulation applied to the wound as it treats the wound. For example, the smart band 120 for wound treatment can reduce the power supplied to the wound by changing the LDO regulator to be used over time. Alternatively, the smart band 120 for wound treatment can change the LDO regulator used during wound treatment so that the power supplied to the wound decreases as the wound recovery rate increases.

The smart band 120 for wound treatment according to an embodiment enables optimized wound treatment by controlling power through a plurality of LDO regulators.

On the other hand, the smart band 120 for wound healing according to an embodiment may also adjust the power supply time in addition to adjusting the amount of power.

5 is a cross-sectional view of a band module of a smart band for wound healing according to an embodiment of the present disclosure.

5, the band module 220 of the smart band 120 for wound treatment includes a polyurethane film 510, a biomimetic material electrode 520, a hydrogel and / or a hydrocolloid 530, A time-limited biomimetic material pattern 540 may be included.

The time-limited biomimetic material pattern 540 comes into contact with a wound on a user's body and electrically stimulates the wound. The time-limited biomimetic material pattern 540 may receive power from the time-limited biomimetic material electrode 520 .

The time-limiting biomimetic material pattern 540 lowers the electrical resistance of the wound through electrical stimulation and maintains electrical signals, thereby enabling rapid treatment. In addition, the thermal energy generated in the process of the time-limited biomimetic material pattern 540 providing electrical stimulation for wound healing can accelerate the melting rate of gelatin and hydrogel included in the smart band 120 for wound healing. can Gelatin and hydrogel for wound treatment melt below 35 degrees, and soften necrotic tissue to promote autolysis. In other words, by accelerating the melting rate of materials such as gelatin and hydrogel and fibroblasts of granulation tissue, they rapidly replace and cross-link collagen, enabling rapid differentiation and growth. let it

In one embodiment, the time-limited biomimetic material pattern 540 may be composed of a two-dimensional structure. In this case, the time-limiting biomimetic material pattern 540 has a magnetic field type characteristic, and a cell can be activated using a pulse-type faradic current for effective treatment.

In one embodiment, the time-limited biomimetic material pattern 540 may be composed of a three-dimensional structure. In this case, the time-limiting biomimetic material pattern 540 has electric field and magnetic field characteristics, and can exhibit more efficient wound healing characteristics than when only a magnetic field is used.

In one embodiment, a hydrogel or hydrocolloid 530 layer may be attached to the first surface of the time-limiting biomimetic material pattern 540 . In this case, the second surface of the time-limiting biomimetic material pattern 540 is in contact with the wound. In some embodiments, a rosin ester layer, a silicone layer, or A composite layer consisting of a combination thereof may be attached.

As wound healing progresses, macrophages that remove foreign substances such as dead cells/bacteria, leukocytes and lysosome enzymes that promote wound healing, and other growth factors are concentrated in the mucus generated during the wound healing process. It can slow wound healing. The hydrogel/hydrocolloid 530 prevents rapid evaporation caused by electrical stimulation and continuously provides a moist environment in which moisture and exudate are properly maintained. Such a humid environment has the advantage of increasing the durability and treatment effect because it is possible to transmit electricity in a wide range with low loss even with a small current in electricity transmission.

The thickness and amount of the hydrogel/hydrocolloid 530 may be used separately according to the amount of exudate from the wound. Conventionally, hydrocolloid dressings have hydrophilic molecules that absorb wound exudate. However, there is a limit to the absorption of exudate, so frequent exchange is required when a large amount of exudate occurs. However, in the smart band 120 for wound treatment of the present disclosure, since the exudate is vaporized while the osmotic pressure phenomenon and exchange are performed according to the heat generated by the time-limited biomimetic device pattern 540, the band exchange according to the saturation of the exudate is prevented. can be minimized. In addition, as described above, since the heat generated by the biomimetic device pattern 540 accelerates the melting rate of gelatin, hydrogel, etc., the smart band 120 for wound treatment of the present disclosure has a time-limiting biomimetic material pattern ( 540) and the hydrogel/hydrocolloid 530 can compensate for the disadvantages of the existing band.

The time-limiting biomimetic material electrode 520 is connected to the communication module 210 through a link and receives power from the communication module 210 . In addition, current is supplied to the time-limited biomimetic material pattern 540 . In order for the time-limiting biomimetic material electrode 520 to supply power to the time-limiting biomimetic material pattern 540, a part of the electrode of the time-limiting biomimetic material is inserted into a part of the hydrogel/hydrocolloid 530 layer. As a result, the time-limiting biomimetic material electrode 520 and the time-limiting biomimetic material pattern 540 can be in physical contact.

The polyurethane film 510 is composed of porous polyethylene and transmits water vapor and air, performs heat exchange, and blocks external pathogens such as bacteria and water droplets. The thickness of the polyurethane film may be designed to be 10 μm or more and 100 μm or less.

In one embodiment, the time-limiting biomimetic material constituting the time-limiting biomimetic material pattern 540, the time-limiting biomimetic material electrode 520, and the time-limiting biomimetic material electrode link are capable of electrical conduction and are capable of changing over time. It can be made of a material that can be degraded according to bioabsorption. For example, nanomolybdenum (Mo), molybdenum disulfide (MoS ₂ ), tungsten disulfide (WS ₂ ), zinc oxide (ZnO), magnesium oxide (MgO), etc. It may be used, but is not limited thereto.

In one embodiment, the time-limited biomimetic material pattern 540, the time-limited biomimetic material electrode 520, and the time-limited biomimetic material electrode link may be configured to have different decomposition rates. For example, in the order of decomposition rate of the time-limited biomimetic material, the time-limited biomimetic material pattern 540 is decomposed first, the time-limited biomimetic material electrode 520 is decomposed next, and the time-limited biomimetic material is decomposed next. The material electrode link may then be configured to be disassembled. For this disassembly order, the thickness of the time-limited biomimetic material pattern 540 is composed of 1 μm or more and 25 μm or less, and the thickness of the time-limited biomimetic material electrode 520 is composed of 30 μm or more and 60 μm or less, The thickness of the time-limiting biomimetic material electrode link may be composed of 50 μm or more and 75 μm or less. In this case, the period of use of the smart band 120 for wound treatment may be adjusted according to the thickness of the time-limited biomimetic material pattern 540 and the time-limited biomimetic material electrode 520, but may be basically set to 18 days. .

6 is a diagram for explaining a wound treatment process by a smart band for wound treatment according to an embodiment of the present disclosure.

Briefly summarizing the wound healing process, the wound healing process generates adenosine triphosphate (ATP) by using oxygen to generate energy in the cell production process. In this process, electrical stimulation activates the 'energy storage' and 'transfer' of ATP. When electrical stimulation of ATP with a high energy level occurs, electrons combine with H ₂ O and move to a lower energy state, releasing a lot of energy. is emitted This electrical stimulation supplies electrical energy and is used in the recovery process.

ATP transmits signals necessary for wound healing, such as epidermal-like growth factor, which is required for tissue repair and wound healing. It also plays a role in activating nicotinamide adenine dinucleotide phosphate (NADPH), which is needed to generate redox signals in damaged cells. NADPH is a negatively charged molecule, ready to bind to positively charged molecules. NADPH also accelerates the production of reactive oxygen species (ROS). ROS helps in the production of leukocytes, and causes phenomena such as cell proliferation and migration due to redox action.

Oxygen is required at all stages of the wound healing process, and ROS stimulate the activation of cytokine and chemokine receptors and other functions necessary for wound repair. In addition, it activates white blood cells and macrophages (a type of white blood cell) for wound healing, and then plays a role in activating fibroblasts. At this time, excess energy is released from the wound and goes out of the body.

When the smart band 120 for wound treatment having the structure proposed in the description through the drawings above is first attached to a wound, a time-limited biomimetic material pattern is inserted into the wound. In this case, healing is achieved through negative electric stimulation signals applied to the epidermis and dermis. This signal stimulates growth factors, and growth factors stimulate granulation tissue with fibroblasts (S610).

In this process, a material that absorbs exudates is required, and hydrogels or hydrocolloids (or hydrogels) are used to absorb exudates. The hydrocolloid (or hydrogel) creates a moist environment while absorbing exudate. When the time-limiting biomimetic material electrically stimulates the wound, heat is generated and the exudate vaporizes, and the exudate is exported to the external barrier by porous polyethylene bonded to the hydrocolloid (or hydrogel). This vaporization process serves to reduce excessive exudate, and by applying electrical stimulation using a time-limiting biomimetic material, it is possible to quickly soothe the heat generated in the process of accelerating and repairing a wound (S620).

In addition, the hydrocolloid, which melts at a low temperature of 30 to 40 degrees, is rapidly melted by electrical stimulation, and the collagen proteins such as pectin and gelatin contained in it meet the wound, changing fibroblasts into new capillaries. help to become In addition, since the time-limiting biomimetic material is absorbed into the living body, excessive electric stimulation using electrodes on the implantable biomimetic device itself is significantly reduced from the middle stage (S630).

As a result, it has the characteristic of seeing an effect similar to 'suture'. These characteristics increase resistance to healing complications (infection), and may improve functional or aesthetic aspects (S640).

Figure 7 is a graph for explaining the test results of the current transmission rate of the wound treatment band according to an embodiment of the present disclosure.

As wound healing progresses, the current used for wound healing tends to decrease. As the wound heals, the resistance to the current provided from the outside increases as the current inside the living body increases, and as the degree of melting of the time-limited biomimetic device increases to treat the wound, the efficiency of current transmission decreases, and finally , Current transmission is high because the exudate of the wound is highly hydrophilic, and the effect of current transmission decreases as the exudate decreases as the wound heals.

Referring to the graph of Figure 7, the results of testing the current transfer rate of the wound in two ways are shown. The two methods are, respectively, a method using only electrodes (710) and an electrode + hydrocolloid method (720). Here, it can be seen that the case of the electrode + hydrocolloid method 720 exhibits a faster treatment effect. At the beginning of wound healing, there is no significant difference because the amount of exudate is small, but after 24 hours (1 Day), the exudate of the wound increases rapidly. Since the smart band 120 for wound treatment of the present disclosure uses an electrode + hydrocolloid method 720 and may have exudate in which the hydrocolloid is liquefied according to the progress of wound treatment, it can be seen that it shows a high current transmission rate can

8 is a graph for explaining a wound healing effect test result of a band for wound healing according to an embodiment of the present disclosure.

Referring to the graph of FIG. 8 , test results of treating wounds in three ways are shown. The three methods are, respectively, a method using only electrodes (810), an electrode + hydrocolloid method (820), and a natural healing method (830).

Since the natural healing method (830) shows an effect of up to 75% of skin tension, the test is compared based on the wound resilience of 75% of the natural healing method (830), but the proposed method, electrode + hydrocolloid method (820) Since the effect was up to 72-73% during these 12 days, a mutual comparison was conducted over the same range of 12 days. In general, even with electrode + hydrocolloid wound treatment, the wound resilience has a limit of up to 85%. However, even in this case, there is an effect of air-induced wound crust. Reflecting these factors, the superiority of the wound resilience of the electrode + hydrocolloid method (820) was verified through a 12-day test.

As above, the disclosed embodiments have been described with reference to the accompanying drawings. Those skilled in the art to which the present disclosure pertains will understand that the present disclosure may be implemented in a form different from the disclosed embodiments without changing the technical spirit or essential features of the present disclosure. The disclosed embodiments are illustrative and should not be construed as limiting.

Claims (10)

In the smart band for wound treatment,
A communication module capable of communicating with an electronic device and including a wireless power transmission function; and
Including a band module attachable to a user's body part,
The communication module,
an antenna and integrated circuit for receiving data and power from the electronic device; one or more low dropout (LDO) regulators supplying power to the band module; And a microcontroller unit (MCU) for controlling the one or more LDO regulators,
The band module,
a time-limiting biomimetic material electrode supplying power from the at least one LDO regulator to a time-limiting biomimetic material pattern; the time-limiting biomimetic material pattern that electrically stimulates the wound by being in contact with the wound of the user's body; and a band providing adhesive force so that the time-limited biomimetic material electrode and the time-limited biomimetic material pattern can be attached to the user's body,
The band module,
Further comprising a hydrogel or hydrocolloid layer attached to the first surface of the layer including the time-limiting biomimetic material pattern,
The second surface of the layer including the time-limiting biomimetic material pattern is in contact with the wound,
The band module,
A first surface of the layer including the time-limiting biomimetic material electrode is attached to the hydrogel or hydrocolloid layer,
A polyurethane film layer is attached to the second surface of the layer including the time-limiting biomimetic material electrode,
A part of the time-limiting biomimetic material electrode is inserted into a part of the hydrogel or hydrocolloid layer to supply power to the time-limiting biomimetic material pattern;
The smart band,
Further comprising a time-limited biomimetic material electrode link for providing an electrical connection between the communication module and the band module,
The time-limited biomimetic material constituting the time-limited biomimetic material pattern, the time-limited biomimetic material electrode, and the time-limited biomimetic material electrode link are materials capable of electrical conduction and capable of being degraded over time and bioabsorbed. consists of,
The smart band,
The time-limited biomimetic material electrode and the time-limited biomimetic material electrode link, respectively The time-limiting biomimetic material is configured,
The order of the decomposition rate of the time-limited biomimetic material is the smart band for wound treatment, which is configured in the order of the time-limited biomimetic material pattern, the time-limited biomimetic material electrode, and the time-limited biomimetic material electrode link. . delete delete delete delete delete According to claim 1,
The one or more LDO regulators,
A first LDO regulator, a second LDO regulator, and a third LDO regulator, wherein the first LDO regulator, the second LDO regulator, and the third LDO regulator have different specifications, a smart band for wound treatment. According to claim 7,
The communication module,
Receiving at least one of wound information and user information from the electronic device;
The MCU,
Controlling the electrical stimulation of the time-limited biomimetic material pattern by controlling at least one of the first LDO regulator, the second LDO regulator, and the third LDO regulator based on at least one of the wound information and user information. , a smart band for wound healing. According to claim 8,
The wound information includes at least one of the size of the wound and the degree of the wound,
The user information includes at least one of gender, age, disease, and obesity, a smart band for wound treatment. According to claim 9,
The thickness of the time-limiting biomimetic material pattern is 1 μm or more and 25 μm or less,
The thickness of the time-limiting biomimetic material electrode is 30 μm or more and 60 μm or less,
The smart band for wound treatment, characterized in that the thickness of the time-limiting biomimetic material electrode link is 50 μm or more and 75 μm or less.

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