KR102550387B1 - Antibacterial skin cleansing composition - Google Patents

Abstract

The present invention relates to an antibacterial skin cleansing composition that is effective in preventing infectious diseases because its antibacterial performance lasts for a long time immediately after washing as well as after washing, and has little skin irritation, and a method for preparing the same.

Description

Antibacterial skin cleansing composition {Antibacterial skin cleansing composition}

The present invention relates to an antibacterial skin cleansing composition that is effective in preventing infectious diseases because its antibacterial performance lasts for a long time immediately after washing as well as after washing, and has little skin irritation, and a method for preparing the same.

Skin cleansing compositions such as face wash, hand wash, shampoo, and body cleanser are used to remove wastes from the skin. These skin cleansing compositions, along with raw materials such as solvents, surfactants, moisturizers, and fragrances, parabens, phenoxyethanol, imidazolinyl urea, and paraoxybenzoic acid esters to prevent decay by microorganisms and product deterioration. It is common to add preservatives such as

However, in the case of the skin cleansing composition as described above, it is possible to reduce the number of bacteria on the skin surface immediately after use, but there is a disadvantage in that the antimicrobial activity is not maintained. In addition, preservatives such as parabens or phenoxyethanol have a problem of causing skin trouble or allergic symptoms due to strong irritation to the skin or eyes.

The present invention has been made to solve the above problems, and an object of the present invention is to provide an antibacterial skin cleansing composition with low skin irritation and long-lasting antibacterial properties and a method for preparing the same.

In order to achieve the above object, according to one embodiment of the present invention, an antibacterial skin cleansing composition comprising purified water, lauryl glycoside, decyl glycoside, glycerin, citric acid, and ethyl lauroyl alginate hydrochloride is provided.

According to another embodiment of the present invention, i) mixing purified water and citric acid at 50 to 90 ° C;

ii) adding lauryl glycoside and decyl glycoside to the mixture of i) and mixing at 50 to 90 °C; and

iii) There is provided a method for preparing the antimicrobial skin cleansing composition comprising the step of adding purified water, glycerin, and ethyllauroylalginate hydrochloride to the mixture of ii) and mixing at 50 to 90 ° C.

The antibacterial skin cleansing composition of the present invention contains ethyl lauroyl alginate hydrochloride as a preservative, so that the antibacterial performance is excellently maintained immediately after washing as well as after a long period of time after washing. In addition, the skin cleaning composition is not toxic to the human body and does not cause skin irritation and trouble, so it can be suitably used as a baby cleanser.

1 is a flow chart showing a method for preparing an antibacterial skin cleansing composition according to an embodiment of the present invention.
2 is an antibacterial test result for general bacteria of the skin cleansing compositions of Examples and Comparative Examples.
3 is an antibacterial test result for Staphylococcus aureus of skin cleansing compositions of Examples and Comparative Examples.

Hereinafter, the present invention will be described in more detail. Terms or words used in this specification and claims should not be construed as being limited to ordinary or dictionary meanings, and the inventor may appropriately define the concept of terms in order to explain his or her invention in the best way. It should be interpreted as a meaning and concept consistent with the technical idea of the present invention based on the principle that there is. Therefore, the configuration described in the embodiments described in this specification is only one of the most preferred embodiments of the present invention and does not represent all of the technical spirit of the present invention, so various equivalents and equivalents that can replace them at the time of this application It should be understood that variations may exist.

The antibacterial skin cleansing composition according to one embodiment of the present invention includes purified water, lauryl glycoside, decyl glycoside, glycerin, citric acid, and ethyl lauroyl alginate hydrochloride.

Ethyl Lauroyl Arginate Hydrochloride (CAS No. 60372-77-2) is a safe preservative registered as a food additive in the US, Australia, and Europe, and is used in many products including food, cosmetics, and medicines. The scope of use is expanding.

The present inventors have repeatedly studied about a skin cleansing composition that can continuously exhibit antibacterial properties immediately after washing as well as after a certain period of time has elapsed after washing, and as a result, lauryl glycoside, decyl glycoside, glycerin, and sheet The present invention was completed by finding that when the ethyllauroyl alginate hydrochloride was included as a preservative together with ric acid, the duration of antibacterial performance of the skin cleansing composition was significantly increased.

In addition, compared to materials such as paraben and phenoxyethanol, which are preservatives previously used in cosmetic compositions, ethyllauroyl alginate hydrochloride does not cause skin irritation or allergy. Therefore, the skin cleansing composition of the present invention can be suitably used for products for infants and young children.

In order to achieve the above effect, ethyllauroyl alginate hydrochloride is 0.01 part by weight or more, 0.05 part by weight or more, or 0.1 part by weight or more, and 0.8 part by weight or less, 0.7 part by weight based on 100 parts by weight of the antibacterial skin cleansing composition Or less, it may be included in 0.6 parts by weight or less, 0.5 parts by weight or less, or 0.4 parts by weight or less. Within this content range, the antibacterial skin cleansing composition can exhibit an excellent cleansing effect, and the antibacterial performance can be continuously exhibited even after washing.

The antibacterial skin cleansing composition of the present invention contains lauryl glycoside and decyl glycoside as surfactants. The lauryl glycoside and decyl glycoside are glucoside-based natural surfactants, and are nonionic and exhibit excellent cleaning power. In addition, it is suitable for use on sensitive skin because it does not irritate the skin, and is eco-friendly due to its excellent biodegradability. In particular, the lauryl glycoside and decyl glycoside show excellent miscibility with ethyllauroyl alginate hydrochloride, so that excellent quality can be realized without phase separation, and these components can be used together to exhibit excellent detergency and antibacterial performance .

0.5 parts by weight or more, 1.0 parts by weight or more, or 1.2 parts by weight or more, and 5 parts by weight or less, 3 parts by weight or less, or 2 parts by weight or less based on 100 parts by weight of the lauryl glycoside antibacterial skin cleansing composition can be included

In addition, the decyl glycoside is 1 part by weight or more, 3 parts by weight or more, or 5 parts by weight or more, and 10 parts by weight or less, 8 parts by weight or less, or 7 parts by weight or less based on 100 parts by weight of the antibacterial skin cleansing composition. content may be included.

Meanwhile, the antimicrobial skin cleansing composition may further include palm kernel/coco glucoside, capryly/capryl glucoside, or a combination thereof as additional natural surfactants in addition to lauryl glycoside and decyl glycoside.

The glycerin is added as a moisturizing component, 0.5 parts by weight or more, 1.0 parts by weight or more, or 1.5 parts by weight or more, and 10 parts by weight or less, 8 parts by weight or less, 6 parts by weight based on 100 parts by weight of the antibacterial skin cleansing composition or less, or 4 parts by weight or less. When the content of glycerin satisfies the above range, the moisturizing performance of the antibacterial skin cleansing composition may be excellent, and the feeling of use may be improved, which is preferable.

The citric acid serves as an acidity regulator, a preservative, and a skin conditioning agent, and is present in an amount of 0.01 part by weight or more, 0.05 part by weight or more, or 0.1 part by weight or more and 1 part by weight or less based on 100 parts by weight of the antibacterial skin cleansing composition. , It may be included in an amount of 0.7 parts by weight or less, or 0.3 parts by weight or less. If the content of citric acid is too small or too large, the pH of the composition does not satisfy the appropriate level, so it is preferable to adjust it within the above range.

The purified water is used as a solvent for dissolving the above components. The content of purified water in the antibacterial skin cleansing composition is not particularly limited, and may be included except for the above-described components and other additives added as needed.

In one embodiment, 100 parts by weight of the antibacterial skin cleaning composition, 0.5 to 5 parts by weight of lauryl glycoside; 1 to 10 parts by weight of decyl glycoside; 0.5 to 10 parts by weight of glycerin; 0.1 to 0.3 parts by weight of citric acid; 0.1 to 0.5 parts by weight of ethyl lauroyl alginate hydrochloride; And the balance may be composed of purified water.

The method for preparing the antibacterial skin cleansing composition is not particularly limited, and purified water, lauryl glycoside, decyl glycoside, glycerin, citric acid, and ethyllauroyl alginate hydrochloride are mixed by a method known in the art can be manufactured.

Specifically, the antibacterial skin cleansing composition comprises: i) mixing purified water and citric acid at 50 to 90 °C; ii) adding lauryl glycoside and decyl glycoside to the mixture of i) and mixing at 50 °C to 90 °C; and iii) adding purified water, glycerin, and ethyllauroyl alginate hydrochloride to the mixture of ii) and mixing at 50°C to 90°C.

When prepared through these steps, the miscibility of each component can be maximized, and a composition with excellent storage stability, which does not cause phase separation even during long-term storage, can be prepared.

Preferably, steps i) to iii) may be performed at a temperature of 60 °C or higher, or 70 °C or higher, and 90 °C or lower, or 80 °C or lower.

However, the manufacturing method of the antibacterial skin cleansing composition is not limited thereto, and may be prepared in various ways by changing the mixing order and conditions of the raw materials.

As described above, the antibacterial skin cleansing composition of the present invention not only has excellent cleansing ability, but also exhibits continuous antibacterial performance as it contains ethyl lauroyl alginate hydrochloride, so that it has antibacterial activity for a long time immediately after washing the skin as well as after washing. this can last

In addition, the antibacterial skin cleansing composition does not contain preservatives such as parabens and phenoxyethanol that cause skin irritation, and contains natural surfactants, so it is friendly to the human body, does not cause skin troubles and allergies, and is suitable for infants and young children. It can also be used suitably for products.

Accordingly, the antibacterial skin cleansing composition may be used for purposes such as face wash, hand wash, shampoo, body cleanser, and baby wash.

Hereinafter, examples will be described in detail to aid understanding of the present invention. However, the following examples are only illustrative of the content of the present invention, and the scope of the present invention is not limited to the following examples.

Example: Preparation of antibacterial skin cleansing composition

Antibacterial skin containing 88.87 parts by weight of purified water, 0.2 parts by weight of citric acid, 1.5 parts by weight of lauryl glycoside, 6.2 parts by weight of decyl glycoside, 2.73 parts by weight of glycerin and 0.5 parts by weight of ethyllauroyl alginate hydrochloride by the following method. A cleaning composition was prepared.

68.87 parts by weight of purified water and 0.2 parts by weight of citric acid were added to a reaction vessel, and mixed by heating to 80 °C.

1.5 parts by weight of lauryl glycoside and 6.2 parts by weight of decyl glycoside were added to the mixture, and mixed by heating to 80 °C.

20 parts by weight of purified water and 2.73 parts by weight of glycerin were added to the mixture, the temperature was adjusted to 70 ° C, and 0.5 parts by weight of ethyl lauroyl alginate hydrochloride was added and mixed to prepare an antibacterial skin cleansing composition.

Experimental Example

In order to evaluate the antibacterial performance of the antibacterial skin cleansing composition of Examples, the change in the number of bacteria on the hands before and after using the detergent composition was measured by the following method (dry film method).

As a comparative example, a commercially available top to toe baby wash (manufacturer: Mamitier) was used.

(1) General bacterial test

1) Blank (before hand washing) measurement: A culture solution was prepared by soaking the hand before washing in 20 ml sterile distilled water for 5 seconds. Then, 1 ml of the culture solution was added dropwise to a general bacterial culture film (3M Petrifilm AC), and cultured at 35 ° C. for 24 hours. Thereafter, the number of bacteria was measured according to the AOAC reading method.

2) Measurement immediately after hand washing: The left hand was washed using the antibacterial skin cleansing composition of Example and the right hand was washed for 20 seconds using the baby wash of Comparative Example, respectively. Immediately after washing, each hand was immersed in 20 ml sterile distilled water for 5 seconds to prepare a culture medium. Then, 1 ml of the culture solution was added dropwise to a general bacterial culture film (3M Petrifilm AC), and cultured at 35 ° C. for 24 hours. Thereafter, the number of bacteria was measured according to the AOAC reading method.

3) Measured after 1 hour, 2 hours, and 3 hours of hand washing: After washing the hands in step 2), daily life was performed for 1 hour, and the hands were soaked in 20 ml of sterile distilled water for 5 seconds to prepare a culture solution. Then, 1 ml of the culture solution was added dropwise to a general bacterial culture film (3M Petrifilm AC), and cultured at 35 ° C. for 24 hours.

Similarly, the same test was repeated for the hands 2 hours and 3 hours after hand washing in 2) above. Thereafter, the number of bacteria was measured according to the AOAC reading method.

(2) Staphylococcus aureus test

Staphylococcus aureus culture film (3M Petrifilm STX) was used as the medium, and the antibacterial performance against Staphylococcus aureus was tested in the same way as the general bacterial test.

The general bacterial test results are shown in FIG. 2 and the staphylococcal test results are shown in FIG. 3 . The upper part of FIGS. 2 and 3 is a comparative example, and the lower part is a result of an example.

2 and 3, in the commercial product of Comparative Example, all bacteria and staphylococci were removed immediately after washing, but the number of bacteria gradually increased again as time passed after washing, especially in the case of staphylococcus 2 to 3 hours after washing. The number of bacteria increased to a level similar to that before washing. From this, it can be confirmed that the commercially available baby wash does not have sustained antibacterial properties.

However, it can be confirmed that the detergent composition of Example has a detectable amount of general bacteria and staphylococci of 0 CFU/ml immediately after washing as well as after 3 hours of washing, and the antibacterial performance lasts for a long time.

As described above, although the embodiments have been described with limited examples and drawings, those skilled in the art can make various modifications and variations from the above description. For example, the described techniques may be performed in an order different from the method described, and/or components of the described system, structure, device, circuit, etc. may be combined or combined in a different form than the method described, or other components may be used. Or even if it is replaced or substituted by equivalents, appropriate results can be achieved. Therefore, other implementations, other embodiments, and equivalents of the claims are within the scope of the following claims.

Claims (4)

As an antibacterial skin cleansing composition,
The composition includes purified water, lauryl glycoside, decyl glycoside, glycerin, citric acid, and ethyl lauroyl alginate hydrochloride,
The composition includes 0.2 parts by weight of citric acid, 1.5 parts by weight of lauryl glycoside, 6.2 parts by weight of decyl glycoside, 2.73 parts by weight of glycerin and 0.5 parts by weight of ethyllauroyl alginate hydrochloride, based on 100 parts by weight of the composition; And the balance includes purified water,
The composition further comprises capryli/caprylglucoside,
Wherein the composition has antibacterial activity against Staphylococcus aureus. delete delete A method for producing the antibacterial skin cleansing composition according to claim 1,
i) mixing purified water and citric acid at 60 to 90 °C;
ii) adding lauryl glycoside and decyl glycoside to the mixture of i) and mixing at 60 to 90 °C; and
iii) A method for preparing an antibacterial skin cleansing composition comprising the step of adding purified water, glycerin, and ethyllauroyl alginate hydrochloride to the mixture of ii) and mixing at 50 to 90 ° C.

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