KR102534536B1 - Composition and manufacturing method effective for antibacterial, antioxidant, and immunity enhancement using Probiotics Lactobacillus and red ginseng in the intestine of companion animal - Google Patents

Abstract

The present invention relates to a health functional composition for companion animals, and more particularly, includes vegetable ingredients to ensure safety and eco-friendliness in the body, while enhancing the fundamental immunity of companion animals to prevent various diseases and infections. It relates to a composition for enhancing immunity for animals.

Description

Composition and manufacturing method effective for antibacterial, antioxidant, and immunity enhancement using Probiotics Lactobacillus and red ginseng in the intestine of companion animals companion animal}

The present invention relates to a health functional composition for companion animals, and more particularly, includes vegetable ingredients to ensure safety and eco-friendliness in the body, while enhancing the fundamental immunity of companion animals to prevent various diseases and infections. It relates to a composition for enhancing immunity for animals.

In modern society, as population structure changes such as the acceleration of aging and the increase of single households are steadily taking place, the number of people who recognize companion animals as family members or life partners, not just pets, is increasing.

Pets live together with people while being protected as members of the family, but they are also exposed to contaminated natural environments such as air and water pollution, processed foods, and stress that people are experiencing, so companion animals also suffer from skin problems that are common to humans. It is inevitably vulnerable to various diseases such as diseases, respiratory diseases, and digestive disorders.

In the past people's perception of the health of companion animals, when companion animals suffer from various diseases and show symptoms, passive care, such as taking them to a veterinary hospital for treatment or prescription for medicine, was sufficient for most post-treatment. However, in recent years, guardians' thoughts on the health of companion animals, like human health care, have focused on methods for preparing for various diseases and infections in advance by improving the more fundamental immune system.

Therefore, in order to enable companion animals to lead a healthier life, technology development for various companion animal feeds, nutrients, medicines, etc. is actively being developed. Accordingly, the size of the domestic companion animal-related market is showing a rapid growth trend every year. indicates For example, the essential nutrients of the pet food composition are evenly blended, or high protein or vitamins and minerals are blended in high content to supplement specific nutrients or physiologically active ingredients, and in addition to feed, companion animals for immunity enhancement are added. They also release nutritional supplements for animals. Alternatively, a program such as a feeding system for companion animals that can effectively feed an appropriate amount of feed and nutritional supplements is being developed.

However, in order to maintain an appropriate unit price level, currently marketed compositions for improving the health of companion animals contain non-natural chemicals or synthetic additives, or add a small amount even if they contain excellent active ingredients derived from nature. In most cases, it is limited to the level of In addition, until now, since the method of using active ingredients for health promotion is limited to including them in feed compositions or nutrients, it is difficult to expect immune-enhancing effects in more diverse aspects.

Therefore, there is a need for a study on a new combination of high-quality ingredients derived from nature to improve the fundamental immune system of companion animals and a composition that can be expected to have immune-enhancing effects in more diverse aspects.

On the other hand, the above-mentioned background art is technical information that the inventor possessed for derivation of the present invention or acquired in the process of derivation of the present invention, and cannot necessarily be said to be known art disclosed to the general public prior to filing the present invention. .

Republic of Korea Patent Publication No. 10-2020-0109871

The present invention is intended to solve the above problems, and is for enhancing immunity for companion animals, which includes plant components to ensure safety and eco-friendliness in the body, while increasing the fundamental immunity of companion animals to prevent various diseases and infections. It is intended to provide a composition.

The above and other objects and advantages of the present invention will become apparent from the following description of preferred embodiments.

The above object, vegetable ingredients including chicory extract; A mixture of lactic acid bacteria, including a lactic acid bacteria strain, and further comprising at least one selected from the group consisting of a culture medium of the lactic acid bacteria strain, a concentrate of the culture medium, and a dried material of the culture medium; red ginseng powder; and additional components including fructooligosaccharides; It can be achieved by a composition for enhancing immunity for companion animals, comprising a.

The lactic acid bacteria mixture is Lactobacillus plantarum, Lactobacillus paracasei, Bifidobacterium longum, Lactobacillus rhamnosus, Bifidobacterium animalis ( Bifidobacterium infantis), Leuconostoc citreum, Streptococcus thermophilus, Lactobacillus casei, Bifidobacterium breve, Bifidobacterium lactis (Bifidobacterium lactis, Bifidobacterium bifidum, Lactobacillus acidophilus, Lactobacillus reuteri, Lactobacillus bulgaricus, Lactobacillus fermentum ), Lactobacillus gasseri, Lactobacillus salivarius, Lactobacillus helveticus and Lactococcus lactis subsp. Characterized in that it comprises a dried product of a culture solution of mixed lactic acid bacteria strains of Rhamnosus, Lactobacillus plantarum, Lactobacillus fermentum and Lactobacillus acidophilus do.

The red ginseng powder and the lactic acid bacteria mixture are mixed in a weight ratio of 100: 40 to 50.

The red ginseng powder, a cutting step of cutting the ginseng washed in water; A first heat treatment step of heat-treating the ginseng cut in the cutting step with steam for 40 to 50 minutes; A first hot air drying step of drying the ginseng subjected to the first heat treatment with hot air at 40 to 50 ° C; A second heat treatment step of heat-treating the ginseng dried in the first hot air drying step with steam for 30 to 40 minutes; A second hot air drying step of drying the ginseng heat-treated in the second heat treatment step at 60 to 75 ° C; and pulverizing the dried red ginseng into powder.

The additional ingredients are characterized in that they further include isomalt, vitamin mix, mineral mix, dizyme and high protein ingredients.

According to the present invention, including probiotics lactic acid bacteria and red ginseng, it is possible to enhance immunity in the intestines of companion animals.

In addition, according to the present invention, by including plant components containing a large amount of active ingredients that exhibit physiological activity such as antibacterial and antioxidant functions, it is possible to prevent various diseases and infections by increasing the fundamental immunity of companion animals while securing safety and eco-friendliness in the body. It is possible to provide a composition for enhancing the immunity of companion animals.

However, the effects of the present invention are not limited to the effects mentioned above, and other effects not mentioned will be clearly understood by those skilled in the art from the description below.

Hereinafter, the present invention will be described in detail with reference to embodiments and drawings of the present invention. These examples are only presented as examples to explain the present invention in more detail, and it will be apparent to those skilled in the art that the scope of the present invention is not limited by these examples. .

In addition, unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of skill in the art to which this invention belongs, and in case of conflict, this specification including definitions of will take precedence.

In order to clearly explain the proposed invention in the drawings, parts irrelevant to the description are omitted, and similar reference numerals are attached to similar parts throughout the specification. And, when a certain component is said to "include", this means that it may further include other components without excluding other components unless otherwise stated. Also, a “unit” described in the specification means one unit or block that performs a specific function.

In each step, the identification code (first, second, etc.) is used for convenience of description, and the identification code does not describe the order of each step, and each step does not clearly describe a specific order in context. It may be performed differently from the order specified above. That is, each step may be performed in the same order as specified, may be performed substantially simultaneously, or may be performed in the reverse order.

One aspect of the present application, a vegetable component containing a chicory extract; A mixture of lactic acid bacteria, including a lactic acid bacteria strain, and further comprising at least one selected from the group consisting of a culture medium of the lactic acid bacteria strain, a concentrate of the culture medium, and a dried material of the culture medium; red ginseng powder; and additional components including fructooligosaccharides; It provides a composition for enhancing the immunity of companion animals.

The chicory is rich in antioxidants such as polyphenols, so it has excellent anti-inflammatory, antioxidant, and immune enhancing effects. In particular, the roots of chicory are very rich in fiber such as inulin, a prebiotic resistant component that serves as food for beneficial bacteria in the intestine, and can exert an effect of promoting beneficial bacteria in the intestine of companion animals. In addition, chicory promotes digestion, prevents reabsorption of cholesterol, lowers cholesterol levels in the body, and exhibits various health functions such as reducing the absorption of glucose.

The chicory extract may be, specifically, chicory root extract powder. The manufacturing method of the chicory root extract powder is not particularly limited, and may follow a known manufacturing method. Alternatively, a commercially available chicory root extract powder product may be used.

The chicory extract is preferably included in an amount of 3 to 8 parts by weight based on 100 parts by weight of red ginseng powder.

The vegetable component may further include one or more selected from goji berry extract, fermented goji berry extract, broccoli extract, and pork potato powder.

Goji berry contains a large amount of nutrients such as betaine, zeaxanthin, vitamins, and minerals, which suppress fatty liver and help regenerate liver cells. In addition, it exhibits various functions such as anti-inflammatory, anti-cancer effects, and vision improvement. In addition, goji berry has a unique savory and sweet flavor, which helps to improve the overall functionality of the immune enhancing composition.

The goji berry is preferably used in the form of fermented goji berry extract. Fermented goji berries can further increase the immunity enhancing effect by including a higher content of antioxidant components such as polyphenols.

The fermented goji berry extract may be included in the form of fermented goji berry extract powder. The method for producing the fermented goji berry extract powder is not particularly limited and may follow a known technique.

Since the broccoli extract contains a large amount of an immune nutrient called broccoli, it can further enhance the immune activity in the body along with the saponin of the red ginseng.

The pork potato is rich in dietary fiber and inulin and serves as a natural lactic acid bacteria growth agent, thereby increasing the number and efficacy of intestinal lactic acid bacteria by 5 to 10 times or more. At the same time, it is possible to further improve intestinal immunity by reducing harmful bacteria and, in particular, by promoting metabolism and increasing activity of bifidobacteria. In addition, it acts as a natural insulin action and is rich in anthocyanins and polyphenols, helping to remove vascular wastes and stabilize cholesterol levels. For example, the pork potato is preferably used in powder form.

In one embodiment, the vegetable component may include a mixture of the fermented goji berry extract, broccoli extract, and pork potato powder in a weight ratio of 2.5: 0.1 to 0.5: 4.0 to 5.0.

The vegetable component may be included in an amount of 5 to 15 parts by weight based on 100 parts by weight of red ginseng powder.

The lactic acid bacteria mixture includes a lactic acid bacteria strain, and may further include one or more selected from the group consisting of a culture solution of the lactic acid bacteria strain, a concentrate of the culture solution, and a dried product of the culture solution.

For example, the lactic acid bacteria mixture is preferably included in an amount of 40 to 50 parts by weight based on 100 parts by weight of the red ginseng powder. When the lactic acid bacteria mixture is included in an amount of less than 40 parts by weight, the content of lactic acid bacteria reaching the intestine is not high, so the effect of enhancing immunity may be somewhat insignificant.

For example, the lactic acid bacteria mixture may be a mixture of the lactic acid bacteria strain and the dried product of the culture medium. In this way, the effect of enhancing the intestinal immunity of companion animals by lactic acid bacteria can be further enhanced.

The lactic acid bacteria strains are, specifically, Lactobacillus plantarum, Lactobacillus paracasei, Bifidobacterium longum, Lactobacillus rhamnosus, Bifidobacterium Bifidobacterium infantis, Leuconostoc citreum, Streptococcus thermophilus, Lactobacillus casei, Bifidobacterium breve, Bifidobacter Bifidobacterium lactis, Bifidobacterium bifidum, Lactobacillus acidophilus, Lactobacillus reuteri, Lactobacillus bulgaricus, Lactobacillus fermentum (Lactobacillus fermentum), Lactobacillus gasseri, Lactobacillus salivarius, Lactobacillus helveticus and Lactococcus lactis subsp. lactis.

The dried product of the culture solution of the lactic acid bacteria strain is Lactobacillus rhamnosus, Lactobacillus plantarum, Lactobacillus fermentum and Lactobacillus acidophilus, respectively. It may be a mixture of the dry matter of the culture medium.

The composition for enhancing immunity may further include additional components such as fructooligosaccharide, isomalt, vitamin mix, mineral mix, and dizyme.

The vitamin mix may be a mixture of vitamins C, K, and niacin (vitamin group B) that can be synthesized in the body, as well as the remaining 13 vitamins that must be consumed as drinking water.

The mineral mix includes calcium, phosphorus, sodium, potassium, chlorine, sulfur, magnesium, which are required in large amounts, and iron, zinc, iodine, copper, selenium, manganese, cobalt, and chromium, which are required in trace amounts. , fluorine, molybdenum, etc. may be mixed.

The additional ingredients may further include high-protein ingredients such as cheese and tuna. In this way, essential amino acids necessary for companion animals can be supplemented as nutrients. The high-protein component may be prepared in the form of a powder by processing according to a known technique commonly used in the art and included in the composition.

The additional components may be included in an amount within the range of 0.5 to 15 parts by weight based on 100 parts by weight of red ginseng powder, each independently of each other.

The red ginseng is rich in ginsenoside and is excellent in immunity enhancement effect. In addition, it exerts various physiological activities such as suppression of platelet aggregation, improvement of blood flow, relief from fatigue, and antioxidant effect.

The method for producing red ginseng powder includes a cutting step of cutting ginseng washed in water; A first heat treatment step of heat-treating the ginseng cut in the cutting step with steam for 40 to 50 minutes; A first hot air drying step of drying the ginseng subjected to the first heat treatment with hot air at 40 to 50 ° C; A second heat treatment step of heat-treating the ginseng dried in the first hot air drying step with steam for 30 to 40 minutes; A second hot air drying step of drying the ginseng heat-treated in the second heat treatment step at 60 to 75 ° C.; and pulverizing the dried red ginseng into powder.

In this case, the first heat treatment and the second heat treatment may be performed by steaming a mixture of water and broccoli extract at a weight ratio of 1:0.25 to 0.35. When ginseng is steam-treated with the mixture, the content of active ingredients such as saponin in ginseng can be further increased.

On the other hand, the composition for enhancing immunity may further include a rice bran mineral. The rice bran mineral is composed of only natural materials and is harmless to the human body, but contains a high content of mineral components in the rice bran, so that various pharmacologically active functions can be exhibited. In particular, it has excellent antioxidant and anticancer effects, helping to enhance the immunity of companion animals.

The method for preparing the rice bran mineral is as follows.

First, rice bran can be prepared and fermented. The fermentation may be performed to decompose and remove pesticide components remaining in rice bran and to increase the extraction content of inorganic salts (minerals) in rice bran.

The fermentation may be performed by useful microorganisms, such as Enterobacter cancerogenus, Pseudomonas pavonaceae, Rhodotorula mucilaginosa, or a combination thereof, and may be performed at a temperature of 40 to 45° C. for 35 to 40 hours. Other fermentation processes may follow known techniques.

Next, moisture in the fermented rice bran may be removed, and primary firing and secondary firing may be performed. The primary firing may be performed according to a conventional technique, for example, at a temperature of less than 1,200 °C, specifically, at a temperature of 950 to 1,200 °C.

The secondary firing may be performed according to a conventional technique at a temperature of, for example, 1,200° C. or higher, specifically, 1,200 to 1,300° C.

By the secondary firing, rice bran mineral crystals, in which only mineral components remain, may be formed in a powder form.

The rice bran mineral is preferably included in the content range of 1 to 2 parts by weight based on 100 parts by weight of red ginseng powder.

The immune-enhancing composition may be prepared in solid form, such as jelly or powder, or in liquid form, such as solution, suspension, emulsion, or oil. For example, the composition for enhancing immunity may be prepared in a powder formulation.

Known additives commonly used according to each formulation may be further included without limitation. The composition, specifically, may be commercialized in the form of nutrients, feed additives, etc., but its application is not limited thereto. In addition, with respect to a specific manufacturing method for preparing the composition into the above-described formulation and product, a known technique commonly used in the art may be followed.

The companion animals may include mammals, birds, reptiles, amphibians, and the like, and may include, for example, dogs, cats, rabbits, hamsters, foxes, weasels, lizards, and the like.

Hereinafter, the configuration of the present invention and its effects will be described in more detail through specific examples and comparative examples. However, these examples are for explaining the present invention in more detail, and the scope of the present invention is not limited to these examples.

[Examples 1 to 6]

According to the above description, a composition for enhancing immunity for companion animals including red ginseng powder, vegetable ingredients, and lactic acid bacteria mixture was prepared according to a known technique.

The components and contents of each composition of Examples 1 to 6 were specifically described in Table 1 below. The unit of content in Table 1 is parts by weight based on 100 parts by weight of red ginseng powder.

[Comparative Example 1 to Comparative Example 2]

Immunity enhancement compositions for companion animals were prepared in the same manner as in Examples, except for the component composition and content of Table 1 below.

<Experimental Example: Confirmation of immunity enhancing effect on companion animals>

Experiments were performed to confirm the immune enhancing effect of the compositions according to Examples 1-6 and Comparative Examples 1-2. The specific test method is as follows.

Ten 6-month-old puppies (Poodle: 5, Bichon: 3 Maltese: 2) were set as an experimental group and 10 dogs of the same type as a negative control group, and then each of the above compositions was fed to the experimental group for 30 days. , The negative control group was fed a commercially available nutritional supplement for puppies. Water was allowed to drink ad libitum during feeding. On the 30th day after feeding, blood was collected from the puppies of the experimental group and negative control group, and the immunoenzyme assay, ELASA, was performed to measure the concentration of IgG (immunoglobulin G), one of the immunoglobulins, to confirm the immunity enhancement effect. As a result, It is shown in Table 2 below. (The concentration of IgG is described as the average value.)

Referring to Table 2, it was confirmed that the compositions of Examples significantly increased the concentration of IgG in the blood compared to Comparative Examples and the negative control group. Among them, it was confirmed that the composition of Example 6 had the most excellent effect.

In this specification, only a few examples of various embodiments performed by the present inventors are described, but the technical spirit of the present invention is not limited or limited thereto, and can be modified and implemented in various ways by those skilled in the art, of course.

Claims (5)

botanical ingredients including chicory extract;
A mixture of lactic acid bacteria, including a lactic acid bacteria strain, and further comprising at least one selected from the group consisting of a culture medium of the lactic acid bacteria strain, a concentrate of the culture medium, and a dried material of the culture medium;
red ginseng powder; and
Additional ingredients including fructooligosaccharides; Containing, a composition for enhancing immunity for companion animals. According to claim 1,
The lactic acid bacteria mixture,
Lactobacillus plantarum, Lactobacillus paracasei, Bifidobacterium longum, Lactobacillus rhamnosus, Bifidobacterium infantis, Ryu Leuconostoc citreum, Streptococcus thermophilus, Lactobacillus casei, Bifidobacterium breve, Bifidobacterium lactis (Bifidobacterium lactis) Bifidobacterium bifidum, Lactobacillus acidophilus, Lactobacillus reuteri, Lactobacillus bulgaricus, Lactobacillus fermentum, Lactobacillus spp. Lactobacillus strains that are a mixture of Lactobacillus gasseri, Lactobacillus salivarius, Lactobacillus helveticus and Lactococcus lactis subsp. lactis;
Containing the dried product of culture broth of mixed lactic acid bacteria strains of Lactobacillus rhamnosus, Lactobacillus plantarum, Lactobacillus fermentum and Lactobacillus acidophilus Characterized in, a composition for enhancing immunity for companion animals. According to claim 2,
The red ginseng powder and the lactic acid bacteria mixture are mixed in a weight ratio of 100: 40 to 50, a composition for enhancing immunity for companion animals. According to claim 1,
The red ginseng powder, a cutting step of cutting the ginseng washed in water; A first heat treatment step of heat-treating the ginseng cut in the cutting step with steam for 40 to 50 minutes; A first hot air drying step of drying the ginseng subjected to the first heat treatment with hot air at 40 to 50 ° C; A second heat treatment step of heat-treating the ginseng dried in the first hot air drying step with steam for 30 to 40 minutes; A second hot air drying step of drying the ginseng heat-treated in the second heat treatment step at 60 to 75 ° C; and pulverizing and powdering the dried red ginseng. According to claim 1,
The additional component is characterized in that it further comprises isomalt, vitamin mix, mineral mix, dizyme and high protein component, immunity enhancement composition for companion animals.