KR102440039B9 - 흡입전달용 핵산 또는 단백질 탑재 폐 계면활성제입자 및 이의 제조 방법 - Google Patents
흡입전달용 핵산 또는 단백질 탑재 폐 계면활성제입자 및 이의 제조 방법Info
- Publication number
- KR102440039B9 KR102440039B9 KR1020210016442A KR20210016442A KR102440039B9 KR 102440039 B9 KR102440039 B9 KR 102440039B9 KR 1020210016442 A KR1020210016442 A KR 1020210016442A KR 20210016442 A KR20210016442 A KR 20210016442A KR 102440039 B9 KR102440039 B9 KR 102440039B9
- Authority
- KR
- South Korea
- Prior art keywords
- protein
- loaded
- manufacturing
- nucleic acid
- pulmonary surfactant
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0082—Lung surfactant, artificial mucus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/395—Alveolar surfactant peptides; Pulmonary surfactant peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1275—Lipoproteins; Chylomicrons; Artificial HDL, LDL, VLDL, protein-free species thereof; Precursors thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Marine Sciences & Fisheries (AREA)
- Biochemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020200013867 | 2020-02-05 | ||
KR20200013867 | 2020-02-05 |
Publications (3)
Publication Number | Publication Date |
---|---|
KR20210100032A KR20210100032A (ko) | 2021-08-13 |
KR102440039B1 KR102440039B1 (ko) | 2022-09-05 |
KR102440039B9 true KR102440039B9 (ko) | 2023-03-23 |
Family
ID=77200771
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020210016442A KR102440039B1 (ko) | 2020-02-05 | 2021-02-05 | 흡입전달용 핵산 또는 단백질 탑재 폐 계면활성제입자 및 이의 제조 방법 |
Country Status (8)
Country | Link |
---|---|
US (1) | US20230092682A1 (ko) |
EP (1) | EP4085900A4 (ko) |
JP (1) | JP2023513132A (ko) |
KR (1) | KR102440039B1 (ko) |
CN (1) | CN115052585A (ko) |
AU (1) | AU2021215673A1 (ko) |
CA (1) | CA3165626A1 (ko) |
WO (1) | WO2021158053A1 (ko) |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998046273A2 (en) * | 1997-04-17 | 1998-10-22 | Paola Leone | Delivery system for gene therapy to the brain |
JP2001002592A (ja) * | 1999-06-18 | 2001-01-09 | Dai Ichi Seiyaku Co Ltd | 遺伝子導入用組成物 |
JP2003012503A (ja) * | 2001-06-22 | 2003-01-15 | Techno Network Shikoku Co Ltd | 脂質ベシクルおよび遺伝子を固定化する方法 |
US20100284969A1 (en) * | 2007-06-05 | 2010-11-11 | Frank Guarnieri | Methods and Compositions for Delivery of Medicaments to the Lungs |
TW201208690A (en) * | 2010-08-05 | 2012-03-01 | Indian Inst Of Technology Iit Bombay | Lipid formulations |
CN103550783A (zh) * | 2013-04-27 | 2014-02-05 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 一种核酸类药物靶向递送系统及其制备方法 |
CN112135604A (zh) * | 2018-05-18 | 2020-12-25 | 韩国科学技术院 | 基于肺表面活性物质的抗癌药物 |
-
2021
- 2021-02-05 CA CA3165626A patent/CA3165626A1/en active Pending
- 2021-02-05 WO PCT/KR2021/001516 patent/WO2021158053A1/ko unknown
- 2021-02-05 KR KR1020210016442A patent/KR102440039B1/ko active IP Right Grant
- 2021-02-05 CN CN202180012745.8A patent/CN115052585A/zh active Pending
- 2021-02-05 US US17/759,491 patent/US20230092682A1/en active Pending
- 2021-02-05 AU AU2021215673A patent/AU2021215673A1/en not_active Abandoned
- 2021-02-05 JP JP2022547235A patent/JP2023513132A/ja active Pending
- 2021-02-05 EP EP21751062.7A patent/EP4085900A4/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
KR20210100032A (ko) | 2021-08-13 |
EP4085900A4 (en) | 2023-07-26 |
US20230092682A1 (en) | 2023-03-23 |
WO2021158053A1 (ko) | 2021-08-12 |
AU2021215673A1 (en) | 2022-09-08 |
CN115052585A (zh) | 2022-09-13 |
JP2023513132A (ja) | 2023-03-30 |
EP4085900A1 (en) | 2022-11-09 |
CA3165626A1 (en) | 2021-08-12 |
KR102440039B1 (ko) | 2022-09-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL286424A (en) | A method for the preparation of lipid-warmed RNA nanoparticles | |
WO2017127807A8 (en) | Crystal structure of crispr cpf1 | |
IL265598A (en) | Enzymes that modify RNA-directed nucleic acids and methods for using them | |
IL265599A (en) | RNA-directed amino acid-modifying enzymes and methods of using them | |
WO2016205749A8 (en) | Novel crispr enzymes and systems | |
EP3009511A3 (en) | Novel crispr enzymes and systems | |
PL3618811T3 (pl) | Proces wytwarzania porowatych cząsteczek krzemionki załadowanych co najmniej jednym związkiem bioaktywnym dostosowanych do dostarczania dopłucnego, donosowego, podjęzykowego i/lub dogardłowego | |
WO2007106683A3 (en) | Biomimetic iron-oxide-containing lipoprotein and related materials | |
GB2492167B (en) | Structured particles | |
WO2003072720A3 (en) | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus | |
WO2016183366A3 (en) | Compositions and methods for silencing expression of hepatitis d virus rna | |
AP2014007389A0 (en) | Method of controlling the corrosion rate of alloy particles, alloy particle with controlled corrosionrate, and articles comprising the particle | |
IL260800B (en) | A test tube for shaking using spheres and a method for extracting deoxyribonucleic acid and/or ribonucleic acid from microorganisms | |
WO2009117134A3 (en) | Aerosolized genetic vaccines and methods of use | |
EP1939455A4 (en) | WHEEL FOR MULTI-SHOVEL FANS AND MANUFACTURING METHOD THEREFOR | |
PT2954889T (pt) | Composição para inalação que contém aclidínio para tratamento da doença pulmonar obstrutiva crónica | |
CO6361899A2 (es) | Pariculas inhalables que comprenden tiotropio | |
KR102440039B9 (ko) | 흡입전달용 핵산 또는 단백질 탑재 폐 계면활성제입자 및 이의 제조 방법 | |
Dua et al. | Targeting microRNAs using nanotechnology in pulmonary diseases. | |
EP3594269A4 (en) | POLYLACTIC ACID PARTICLES AND THEIR MANUFACTURING PROCESS | |
WO2011094598A3 (en) | Compositions and methods for reversing corticosteroid resistance or treating respiratory infections | |
PL3499610T3 (pl) | Cząstki materiału czynnego elektrody dodatniej każda zawierająca rdzeń zawierający tlenek litu kobaltu oraz osłonę zawierającą fosforan litu kobaltu oraz sposób ich wytwarzania | |
BR112017023351A2 (pt) | composições multidrogas de matriz frágil | |
SG11202111066UA (en) | High density lipoprotein nanoparticles and rna templated lipoprotein particles for ocular therapy | |
IL189195A0 (en) | A combination of compounds, which can be used in the treatment of respiratory diseases, especially chronic obstructive pulmonary disease (copd) and asthma |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A302 | Request for accelerated examination | ||
E902 | Notification of reason for refusal | ||
E90F | Notification of reason for final refusal | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
G170 | Re-publication after modification of scope of protection [patent] |