KR102370479B1 - 수학적 모형 함수로서의 환자-특이적 투여법용 의약 - Google Patents
수학적 모형 함수로서의 환자-특이적 투여법용 의약 Download PDFInfo
- Publication number
- KR102370479B1 KR102370479B1 KR1020217005789A KR20217005789A KR102370479B1 KR 102370479 B1 KR102370479 B1 KR 102370479B1 KR 1020217005789 A KR1020217005789 A KR 1020217005789A KR 20217005789 A KR20217005789 A KR 20217005789A KR 102370479 B1 KR102370479 B1 KR 102370479B1
- Authority
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- South Korea
- Prior art keywords
- patient
- model
- dosing regimen
- response
- pharmaceutical formulation
- Prior art date
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
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- G06N7/005—
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N7/00—Computing arrangements based on specific mathematical models
- G06N7/01—Probabilistic graphical models, e.g. probabilistic networks
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
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- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Data Mining & Analysis (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Theoretical Computer Science (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Databases & Information Systems (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Algebra (AREA)
- Probability & Statistics with Applications (AREA)
- General Engineering & Computer Science (AREA)
- Computing Systems (AREA)
- Pure & Applied Mathematics (AREA)
- Mathematical Optimization (AREA)
- Mathematical Analysis (AREA)
- Evolutionary Computation (AREA)
- Computational Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mathematical Physics (AREA)
- Software Systems (AREA)
- Artificial Intelligence (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Medical Treatment And Welfare Office Work (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020227006798A KR102450486B1 (ko) | 2012-10-05 | 2013-10-07 | 수학적 모형 함수로서 환자-특이적 투여법을 제공하는 시스템 및 방법 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261710330P | 2012-10-05 | 2012-10-05 | |
| US61/710,330 | 2012-10-05 | ||
| PCT/US2013/063691 WO2014055978A1 (en) | 2012-10-05 | 2013-10-07 | System and method for providing patient-specific dosing as a function of mathematical models |
| KR1020157011564A KR102223018B1 (ko) | 2012-10-05 | 2013-10-07 | 수학적 모형 함수로서 환자-특이적 투여법을 제공하는 시스템 및 방법 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157011564A Division KR102223018B1 (ko) | 2012-10-05 | 2013-10-07 | 수학적 모형 함수로서 환자-특이적 투여법을 제공하는 시스템 및 방법 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020227006798A Division KR102450486B1 (ko) | 2012-10-05 | 2013-10-07 | 수학적 모형 함수로서 환자-특이적 투여법을 제공하는 시스템 및 방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20210025697A KR20210025697A (ko) | 2021-03-09 |
| KR102370479B1 true KR102370479B1 (ko) | 2022-03-04 |
Family
ID=50433375
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157011564A Active KR102223018B1 (ko) | 2012-10-05 | 2013-10-07 | 수학적 모형 함수로서 환자-특이적 투여법을 제공하는 시스템 및 방법 |
| KR1020227006798A Active KR102450486B1 (ko) | 2012-10-05 | 2013-10-07 | 수학적 모형 함수로서 환자-특이적 투여법을 제공하는 시스템 및 방법 |
| KR1020217005789A Active KR102370479B1 (ko) | 2012-10-05 | 2013-10-07 | 수학적 모형 함수로서의 환자-특이적 투여법용 의약 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157011564A Active KR102223018B1 (ko) | 2012-10-05 | 2013-10-07 | 수학적 모형 함수로서 환자-특이적 투여법을 제공하는 시스템 및 방법 |
| KR1020227006798A Active KR102450486B1 (ko) | 2012-10-05 | 2013-10-07 | 수학적 모형 함수로서 환자-특이적 투여법을 제공하는 시스템 및 방법 |
Country Status (9)
| Country | Link |
|---|---|
| US (6) | US10083400B2 (enExample) |
| EP (2) | EP4224482A1 (enExample) |
| JP (5) | JP6412499B2 (enExample) |
| KR (3) | KR102223018B1 (enExample) |
| AU (4) | AU2013326801A1 (enExample) |
| CA (1) | CA2887072C (enExample) |
| IL (3) | IL238115B (enExample) |
| SG (2) | SG10201907682RA (enExample) |
| WO (1) | WO2014055978A1 (enExample) |
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| US9238100B2 (en) | 2012-06-07 | 2016-01-19 | Tandem Diabetes Care, Inc. | Device and method for training users of ambulatory medical devices |
| US10083400B2 (en) | 2012-10-05 | 2018-09-25 | Diane R. MOULD | System and method for providing patient-specific dosing as a function of mathematical models updated to account for an observed patient response |
| US9238144B2 (en) * | 2013-03-14 | 2016-01-19 | Neuropace, Inc. | Optimizing data retrieval from an active implantable medical device |
| WO2017180807A1 (en) | 2016-04-15 | 2017-10-19 | Baxalta Incorporated | Method and apparatus for providing a pharmacokinetic drug dosing regiment |
| US10325687B2 (en) * | 2013-12-06 | 2019-06-18 | Bioverativ Therapeutics Inc. | Population pharmacokinetics tools and uses thereof |
| US9667321B2 (en) * | 2014-10-31 | 2017-05-30 | Pearson Education, Inc. | Predictive recommendation engine |
| CN107004006A (zh) | 2014-10-30 | 2017-08-01 | 培生教育公司 | 内容数据库的生成 |
| ITMI20142149A1 (it) * | 2014-12-16 | 2016-06-16 | L I A Di Giuseppe Capasso | Apparato di diagnosi differenziale in medicina adattato per determinare la sequenza di test ottimale atta ad identificare una patologia secondo criteri di appropriatezza diagnostica |
| EP3271718A4 (en) * | 2015-03-18 | 2018-11-14 | The Regents of the University of California | Phenotypic personalized medicine: adaptive optimization of patient-specific combination therapy |
| AU2016245862A1 (en) * | 2015-04-09 | 2018-02-22 | Diane R. Mould | Systems and methods for patient-specific dosing |
| JP7029753B2 (ja) * | 2016-02-26 | 2022-03-04 | 株式会社豊崎会計事務所 | 情報処理装置 |
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| GB201708624D0 (en) * | 2017-05-31 | 2017-07-12 | Sensidose Ab | System for evaluating dosage parameters |
| US20190065684A1 (en) * | 2017-08-24 | 2019-02-28 | Fitmylife Health Analytics Inc. | Computer program products, methods, and systems for assisting a user to achieve a health-related goal |
| CN111033635B (zh) * | 2017-08-30 | 2024-01-30 | 皇家飞利浦有限公司 | 基于模型和成像数据的冠状动脉健康状态预测 |
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| US20210035672A1 (en) * | 2018-04-05 | 2021-02-04 | University Of Maryland, Baltimore | Method and apparatus for individualized administration of medicaments for delivery within a therapeutic range |
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| KR102062157B1 (ko) * | 2019-04-29 | 2020-01-03 | 오케스트로 주식회사 | 가상 머신 배치 방법 및 이를 구현하는 가상 머신 배치 장치 |
| JP7342491B2 (ja) * | 2019-07-25 | 2023-09-12 | オムロン株式会社 | 推論装置、推論方法、及び推論プログラム |
| KR102527404B1 (ko) * | 2019-10-29 | 2023-05-02 | 고려대학교 산학협력단 | 인슐린 투여량 조절 방법 |
| US11823782B2 (en) | 2020-03-03 | 2023-11-21 | Optum, Inc. | Systems, methods, apparatuses, and computer program products for administering pain management solutions remotely |
| US11075010B1 (en) | 2020-03-19 | 2021-07-27 | Insight RX, Inc. | Pharmacology model optimization based on distributed data acquisition |
| US20210304846A1 (en) * | 2020-03-29 | 2021-09-30 | Stephen J. Brown | Personalized compounding of therapeutic components and tracking of their influence on a measured parameter using a complex interaction model |
| JP2023523246A (ja) * | 2020-04-29 | 2023-06-02 | ノバルティス アーゲー | 患者の眼における疾患又は症状の活動性レベルを評価するためのコンピュータ実施システム及び方法 |
| US20210375455A1 (en) * | 2020-05-27 | 2021-12-02 | MediSync, Inc. | Artificial intelligence systems that incorporate expert knowledge related to heart failure |
| US12205705B2 (en) * | 2020-07-22 | 2025-01-21 | Optimdosing Llc | Smart nutrition dosing |
| KR102559883B1 (ko) * | 2020-09-03 | 2023-07-25 | 한양대학교 산학협력단 | 마르코프 의사결정 과정을 이용하는 투약 전략 생성 방법 |
| JP2024527230A (ja) | 2021-05-29 | 2024-07-24 | ダイアン アール. モールド, | モノクローナル抗体ノモグラムのためのシステムおよび方法 |
| KR20230036545A (ko) | 2021-09-07 | 2023-03-14 | 서울대학교산학협력단 | 적응적 설계 최적화 기반으로 하는 실험 최적화 시스템 및 그 방법 |
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| KR102821516B1 (ko) * | 2022-02-28 | 2025-06-17 | 한국전자기술연구원 | 목표 농도 조절 주입을 지원하는 약물 투여 장치 및 방법 |
| EP4515558A1 (en) * | 2022-04-28 | 2025-03-05 | Regents of the University of Michigan | Closed-loop architecture for distributing and administering medicines to patients |
| KR102447046B1 (ko) * | 2022-06-03 | 2022-09-26 | 주식회사 인투인월드 | 인공지능 기반 임상시험 프로토콜 설계 방법, 장치 및 시스템 |
| US12073931B2 (en) * | 2022-06-15 | 2024-08-27 | Express Scripts Strategic Development, Inc. | Alternate dose regimen identification system |
| CN120500626A (zh) | 2022-09-15 | 2025-08-15 | 雅培实验室 | Hbv诊断、预后和治疗方法及产品 |
| KR102873330B1 (ko) * | 2022-09-23 | 2025-10-21 | 재단법인 아산사회복지재단 | 머신러닝 기술을 활용한 항응고제 초기 적정 용량 예측 방법 및 장치 |
Citations (2)
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| JP2012123837A (ja) | 2005-11-29 | 2012-06-28 | Children's Hospital Medical Center | 薬物選択及び投薬の最適化及び個別化 |
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| AU2016245862A1 (en) | 2015-04-09 | 2018-02-22 | Diane R. Mould | Systems and methods for patient-specific dosing |
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2013
- 2013-10-07 US US14/047,545 patent/US10083400B2/en active Active
- 2013-10-07 CA CA2887072A patent/CA2887072C/en active Active
- 2013-10-07 EP EP23173217.3A patent/EP4224482A1/en active Pending
- 2013-10-07 JP JP2015535867A patent/JP6412499B2/ja active Active
- 2013-10-07 KR KR1020157011564A patent/KR102223018B1/ko active Active
- 2013-10-07 EP EP13843939.3A patent/EP2904388B1/en active Active
- 2013-10-07 SG SG10201907682R patent/SG10201907682RA/en unknown
- 2013-10-07 AU AU2013326801A patent/AU2013326801A1/en not_active Abandoned
- 2013-10-07 WO PCT/US2013/063691 patent/WO2014055978A1/en not_active Ceased
- 2013-10-07 KR KR1020227006798A patent/KR102450486B1/ko active Active
- 2013-10-07 SG SG11201502616WA patent/SG11201502616WA/en unknown
- 2013-10-07 KR KR1020217005789A patent/KR102370479B1/ko active Active
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2014
- 2014-08-12 US US14/457,601 patent/US10706364B2/en active Active
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2015
- 2015-04-02 IL IL238115A patent/IL238115B/en active IP Right Grant
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2017
- 2017-10-11 US US15/730,112 patent/US10268966B2/en active Active
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2018
- 2018-09-28 JP JP2018183803A patent/JP6653365B2/ja active Active
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2019
- 2019-01-07 IL IL264125A patent/IL264125B/en active IP Right Grant
- 2019-02-08 US US16/271,528 patent/US10740687B2/en active Active
- 2019-09-19 AU AU2019232874A patent/AU2019232874A1/en not_active Abandoned
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2020
- 2020-01-27 JP JP2020010887A patent/JP2020080161A/ja not_active Withdrawn
- 2020-02-19 IL IL272760A patent/IL272760B/en unknown
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060036619A1 (en) | 2004-08-09 | 2006-02-16 | Oren Fuerst | Method for accessing and analyzing medically related information from multiple sources collected into one or more databases for deriving illness probability and/or for generating alerts for the detection of emergency events relating to disease management including HIV and SARS, and for syndromic surveillance of infectious disease and for predicting risk of adverse events to one or more drugs |
| JP2012123837A (ja) | 2005-11-29 | 2012-06-28 | Children's Hospital Medical Center | 薬物選択及び投薬の最適化及び個別化 |
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