KR102360880B1 - Endolysins LysPALS21 of Jumbo bacteriophage PALS2 from Staphylococcus aureus - Google Patents
Endolysins LysPALS21 of Jumbo bacteriophage PALS2 from Staphylococcus aureus Download PDFInfo
- Publication number
- KR102360880B1 KR102360880B1 KR1020210090965A KR20210090965A KR102360880B1 KR 102360880 B1 KR102360880 B1 KR 102360880B1 KR 1020210090965 A KR1020210090965 A KR 1020210090965A KR 20210090965 A KR20210090965 A KR 20210090965A KR 102360880 B1 KR102360880 B1 KR 102360880B1
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- South Korea
- Prior art keywords
- lyspals21
- bacteriophage
- staphylococcus aureus
- endolysin
- pals2
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- Plant Pathology (AREA)
Abstract
본 발명은 점보박테리오파지 PALS2 및 그 유래의 엔도라이신 LysPALS21과 LysPALS22에 관한 것으로, 더욱 구체적으로는 황색포도상구균(Staphylococcus aureus)에 대해 숙주별 감수성을 가지는 점보박테리오파지 PALS2 및 그 유래의 엔도라이신 LysPALS21과 LysPALS22에 관한 것이다. 본 발명의 점보박테리오파지 PALS2는 황색포도상구균에 대한 넓은 용균 활성범위를 가지며, 특히 메티실린 항생제에 감수성이 있는 포도상구균 세균(MSSA)과 메티실린에 저항성을 갖는 황색포도상구균 세균(MRSA)에도 높은 용균활성을 가진다. 또한, 본 발명의 점보박테리오파지 PALS2 유래 엔도라이신 LysPALS21은 황색포도상구균에 대해 넓은 범위의 용균 작용을 나타내고 그람양성균인 엔테로코쿠스 페칼리스(Enterococcus faecalis)에서도 높은 용균활성을 발휘할 수 있다. 또한, 본 발명의 점보박테리오파지 PALS2 유래 엔도라이신 LysPALS22는 특정버퍼조건에서 엔도라이신 LysPALS21을 보조하여 보다 효과적인 용균 활성을 발휘할 수 있다.The present invention relates to jumbo bacteriophage PALS2 and its derived endolysins LysPALS21 and LysPALS22, and more specifically, to jumbobacteriophage PALS2 and its derived endolysins LysPALS21 and LysPALS22 with host-specific sensitivity to Staphylococcus aureus . it's about The jumbo bacteriophage PALS2 of the present invention has a wide lytic activity range against Staphylococcus aureus, and in particular, Staphylococcus aureus bacteria (MSSA) that are sensitive to methicillin antibiotics and Staphylococcus aureus bacteria (MRSA) resistant to methicillin (MRSA) also have high lysis have activity. In addition, the jumbo bacteriophage PALS2-derived endolysin LysPALS21 of the present invention exhibits a wide range of lytic activity against Staphylococcus aureus, and can exhibit high lytic activity even in Gram-positive bacteria, Enterococcus faecalis . In addition, the jumbobacteriophage PALS2-derived endolysin LysPALS22 of the present invention can exhibit more effective lytic activity by assisting the endolysin LysPALS21 under specific buffer conditions.
Description
본 발명은 점보박테리오파지 PALS2 및 그 유래의 엔도라이신 LysPALS21과 LysPALS22에 관한 것으로, 더욱 구체적으로는 황색포도상구균(Staphylococcus aureus)에 대해 숙주별 감수성을 가지는 점보박테리오파지 PALS2 및 그 유래의 엔도라이신 LysPALS21과 LysPALS22에 관한 것이다.The present invention relates to jumbo bacteriophage PALS2 and its derived endolysins LysPALS21 and LysPALS22, and more specifically, to jumbobacteriophage PALS2 and its derived endolysins LysPALS21 and LysPALS22 with host-specific sensitivity to Staphylococcus aureus . it's about
황색포도상구균(Staphylococcus aureus)은 그람 양성균으로, 포자를 형성하지 않는 통성혐기성균으로, 주로 가축 분변, 염증 상처 부위 혹은 사람의 손이 많이 닿는 조리도구 등에서 발견된다. 이는 인간과 동물에 감염하여 수술 후 감염, 농양, 심장 내막염 및 독소 증후군 등의 심각한 질병을 유도하기도 한다. 또한, 포도상구균은 TSST-1, EF, 알파, 베타, 델타 독소 등 열에 강한 독소를 생성하기 때문에, 쉽게 사멸되지 않고, 심각한 식중독을 유발하기도 한다. 상기와 같은 특징이 있는 황색포도상구균을 제어하기 위해, 현재까지는 항생제가 주로 사용되어 왔다.하지만, 항생제의 광범위한 사용은 메티실린 저항성 황색포도상구균(Methicillin-resistant S. aureus) 등 항생제에 대해 저항성을 보이는 세균을 발생시키는 문제를 초래했다.Staphylococcus aureus ( Staphylococcus aureus ) is a Gram-positive, non-spore-forming, facultative anaerobic bacteria, mainly found in livestock feces, inflamed wounds, or cooking utensils that are touched by people's hands. It infects humans and animals, leading to serious diseases such as postoperative infections, abscesses, endocarditis and toxin syndrome. In addition, since Staphylococcus aureus produces heat-resistant toxins such as TSST-1, EF, alpha, beta, and delta toxins, it is not easily killed and may cause serious food poisoning. In order to control Staphylococcus aureus having the above characteristics, antibiotics have been mainly used until now. However, the widespread use of antibiotics has resulted in resistance to antibiotics such as methicillin-resistant S. aureus . It caused the problem of generating visible bacteria.
최근 이러한 문제를 극복하기 위한 방안으로 박테리오파지 및 박테리오파지 유래의 엔도라이신을 사용하는 것이 대안으로 떠오르고 있다. 박테리오파지는 세균을 특이적으로 감염하는 바이러스의 일종으로, 식품, 토양, 하수 및 해수 등 지구상의 다양한 환경에 존재하며, 크게 용균성 생활사(lytic cycle)만을 반복하는 독성 파지(virulent phage)와, 용균성 생활사와 용원성 생활사(lysogenic cycle)를 모두 거치는 약독성 파지(temperate phage)로 분류된다. 독성 파지의 경우, 세균 감염 약 30분 후에 100~200개의 새로운 파지를 만들어 세균의 막을 파괴하며 밖으로 나와 용균시키는데, 세균의 증식속도보다 파지의 증식속도가 훨씬 빠르므로 세균의 증식을 제한하는 중요한 요인이 될 수 있다. 약독성 파지의 경우, 숙주세균의 유전자에 파지의 유전자 정보를 넣어 파지의 모양이 사라지고 숙주 세균이 파괴되지 않는다. 이런 상태는 숙주세균이 좋은 환경조건에 있는 한 지속되는데, 환경이 악화되면 숙주세균의 유전자에 있던 일부의 파지 유전자는 용균 사이클로 바뀌고 새로운 파지를 만들어 숙주세균을 용균시켜 숙주세포 밖으로 방출된다. 이와 같은 이유로 독성 파지를 이용하여 다양한 질병을 성공적으로 예방 및 치료한 사례가 보고되고 있다. Recently, as a way to overcome this problem, the use of bacteriophages and bacteriophage-derived endolysin is emerging as an alternative. Bacteriophage is a kind of virus that specifically infects bacteria. It exists in various environments on the earth such as food, soil, sewage and seawater. It is classified as a temperate phage that goes through both a fungal and a lysogenic cycle. In the case of toxic phages, about 30 minutes after bacterial infection, 100 to 200 new phages are made and lysed by breaking the bacterial membrane. this can be In the case of weakly toxic phage, the shape of the phage is lost by inserting the genetic information of the phage into the gene of the host bacteria, and the host bacteria is not destroyed. This state persists as long as the host bacteria are in favorable environmental conditions. When the environment deteriorates, some of the phage genes in the host bacteria's genes are changed to the lysis cycle, and new phages are lysed to lyse the host bacteria and released out of the host cell. For this reason, cases of successfully preventing and treating various diseases using toxic phages have been reported.
한편, 엔도라이신(리신)은 박테리오파지가 세균 세포벽의 펩티도글리칸을 분해하기 위해 만드는 효소로서, 박테리오파지의 용균 생활사 마지막 단계에 비리온(virion)을 세포 밖으로 방출시킬 때 사용된다. 엔도라이신은 세균 세포벽 내의 펩티도글리칸(peptidoglycan)의 특정 연결부위를 절단하는 작용기작을 보유하며, 이러한 특성을 내성 문제를 근본적으로 해결할 수 있어 새로운 계열의 항생물질로서 주목받고 있다. 하지만, 황색포도상구균을 효과적으로 억제하기 위한 박테리오파지 및 이로부터 유래한 엔도라이신에 대한 기술은 아직 미미하며, 다양한 균주에 대한 용균활성능을 가지는 효과적인 항생제 대체제의 개발이 필요한 실정이다.On the other hand, endolysin (lysine) is an enzyme made by a bacteriophage to decompose peptidoglycan of a bacterial cell wall, and is used when releasing virions out of the cell at the last stage of the lytic life cycle of the bacteriophage. Endolysin has a mechanism of action that cuts a specific linkage of peptidoglycan in the bacterial cell wall, and this characteristic can fundamentally solve the problem of resistance, so it is attracting attention as a new class of antibiotics. However, the technology for bacteriophage and endolysin derived therefrom for effectively inhibiting Staphylococcus aureus is still insignificant, and there is a need to develop an effective alternative to antibiotics having lytic activity against various strains.
본 발명은 황색포도상구균(Staphylococcus aureus) 및 포도상구균 속의 다양한 균주에 대해 용해능을 가지고 있는, 황색포도상구균 파지에서 처음 보고된 점보박테리오파지 PALS2와 그 유래 2개의 엔도라이신 LysPALS21 및 LysPALS22를 제공하고자 한다.The present invention aims to provide a jumbobacteriophage PALS2 first reported from Staphylococcus aureus phage and two endolysins LysPALS21 and LysPALS22 derived therefrom, which have lytic ability against Staphylococcus aureus and various strains of the genus Staphylococcus.
본 발명은 황색포도상구균에 대해 용균 활성이 있는 것을 특징으로 하는 박테리오파지 PALS2(KACC97035P)를 제공한다.The present invention provides a bacteriophage PALS2 (KACC97035P), characterized in that it has lytic activity against Staphylococcus aureus.
한편, 본 발명에 있어서, 상기 황색포도상구균은, 일예로 메티실린 저항성 황색포도상구균(Methicillin-resistant S. aureus, MRSA) 또는 메티실린 감수성 황색포도상구균(Methicillin-sensitivity S. aureus, MSSA)인 것일 수 있다.Meanwhile, in the present invention, the Staphylococcus aureus is, for example, methicillin-resistant S. aureus (MRSA) or methicillin-sensitive Staphylococcus aureus (Methicillin-sensitivity S. aureus , MSSA). can
또한, 황색포도상구균에 대해 용균 활성이 있는 것을 특징으로 하는 서열번호 3의 아미노산 서열로 구성된 엔도라이신 LysPALS21를 제공한다.In addition, it provides an endolysin LysPALS21 composed of the amino acid sequence of SEQ ID NO: 3, characterized in that it has lytic activity against Staphylococcus aureus.
또한, 황색포도상구균에 대해 용균 활성이 있는 것을 특징으로 하는 서열번호 5의 아미노산 서열로 구성된 엔도라이신 LysPALS22를 제공한다.In addition, it provides an endolysin LysPALS22 composed of the amino acid sequence of SEQ ID NO: 5, characterized in that it has lytic activity against Staphylococcus aureus.
한편, 본 발명에 있어서, 상기 황색포도상구균은, 일예로 메티실린 저항성 황색포도상구균(Methicillin-resistant S. aureus, MRSA) 또는 메티실린 감수성 황색포도상구균(Methicillin-sensitivity S. aureus, MSSA)인 것일 수 있다.Meanwhile, in the present invention, the Staphylococcus aureus is, for example, methicillin-resistant S. aureus (MRSA) or methicillin-sensitive Staphylococcus aureus (Methicillin-sensitivity S. aureus , MSSA). can
또한, 본 발명은 박테리오파지 PALS2(KACC97035P), 서열번호 3의 아미노산 서열로 구성된 엔도라이신 LysPALS21 또는 서열번호 5의 아미노산 서열로 구성된 엔도라이신 LysPALS22 중에서 선택되는 어느 하나 이상을 포함하는 것을 특징으로 하는 황색포도상구균 감염 질환의 개선용 식품 조성물을 제공한다.In addition, the present invention is bacteriophage PALS2 (KACC97035P), endolysin LysPALS21 consisting of the amino acid sequence of SEQ ID NO: 3, or endolysin LysPALS22 consisting of the amino acid sequence of SEQ ID NO: 5 Staphylococcus aureus, characterized in that it comprises at least one selected from It provides a food composition for improving infectious diseases.
또한, 본 발명은 박테리오파지 PALS2(KACC97035P), 서열번호 3의 아미노산 서열로 구성된 엔도라이신 LysPALS21 또는 서열번호 5의 아미노산 서열로 구성된 엔도라이신 LysPALS22 중에서 선택되는 어느 하나 이상을 포함하는 것을 특징으로 하는 황색포도상구균 감염 질환의 예방 또는 치료용 약학 조성물을 제공한다.In addition, the present invention is bacteriophage PALS2 (KACC97035P), endolysin LysPALS21 consisting of the amino acid sequence of SEQ ID NO: 3, or endolysin LysPALS22 consisting of the amino acid sequence of SEQ ID NO: 5 Staphylococcus aureus, characterized in that it comprises at least one selected from It provides a pharmaceutical composition for preventing or treating an infectious disease.
또한, 본 발명은 박테리오파지 PALS2(KACC97035P), 서열번호 3의 아미노산 서열로 구성된 엔도라이신 LysPALS21 또는 서열번호 5의 아미노산 서열로 구성된 엔도라이신 LysPALS22 중에서 선택되는 어느 하나 이상을 포함하는 것을 특징으로 하는 사료 조성물을 제공한다.In addition, the present invention provides a feed composition comprising at least one selected from bacteriophage PALS2 (KACC97035P), endolysin LysPALS21 consisting of the amino acid sequence of SEQ ID NO: 3, or endolysin LysPALS22 consisting of the amino acid sequence of SEQ ID NO: 5 to provide.
또한, 본 발명은 박테리오파지 PALS2(KACC97035P), 서열번호 3의 아미노산 서열로 구성된 엔도라이신 LysPALS21 또는 서열번호 5의 아미노산 서열로 구성된 엔도라이신 LysPALS22 중에서 선택되는 어느 하나 이상을 포함하는 것을 특징으로 하는 세정제 조성물을 제공한다.In addition, the present invention provides a cleaning composition comprising at least one selected from bacteriophage PALS2 (KACC97035P), endolysin LysPALS21 consisting of the amino acid sequence of SEQ ID NO: 3, or endolysin LysPALS22 consisting of the amino acid sequence of SEQ ID NO: 5 to provide.
본 발명의 점보박테리오파지 PALS2는 황색포도상구균에 대한 넓은 용균 활성범위를 가지며, 특히 메티실린 항생제에 감수성이 있는 포도상구균 세균(MSSA)과 메티실린에 저항성을 갖는 황색포도상구균 세균(MRSA)에도 높은 용균활성을 가진다. The jumbo bacteriophage PALS2 of the present invention has a wide lytic activity range against Staphylococcus aureus, and in particular, Staphylococcus aureus bacteria (MSSA) that are sensitive to methicillin antibiotics and Staphylococcus aureus bacteria (MRSA) resistant to methicillin (MRSA) also have high lysis have activity.
또한, 본 발명의 점보박테리오파지 PALS2 유래 엔도라이신 LysPALS21은 황색포도상구균에 대해 넓은 범위의 용균 작용을 나타내고 그람양성균인 엔테로코쿠스 페칼리스(Enterococcus faecalis)에서도 높은 용균활성을 발휘할 수 있다. 또한, 본 발명의 점보박테리오파지 PALS2 유래 엔도라이신 LysPALS22는 특정버퍼조건에서 엔도라이신 LysPALS21을 보조하여 보다 효과적인 용균 활성을 발휘할 수 있다.In addition, the jumbo bacteriophage PALS2-derived endolysin LysPALS21 of the present invention exhibits a wide range of lytic activity against Staphylococcus aureus, and can exhibit high lytic activity even in Gram-positive bacteria, Enterococcus faecalis . In addition, the jumbobacteriophage PALS2-derived endolysin LysPALS22 of the present invention can exhibit more effective lytic activity by assisting the endolysin LysPALS21 under specific buffer conditions.
도 1은 본 발명의 점보박테리오파지 PALS2의 전자현미경 사진이다.
도 2는 본 발명의 점보박테리오파지 PALS2의 유전체 분석 결과이다.
도 3은 본 발명의 점보박테리오파지 PALS2의 황색포도상구균에 대한 용균활성능을 나타낸 결과이다.
도 4는 본 발명의 점보박테리오파지 PALS2 유래 엔도라이신 LysPALS21과 LysPALS22의 유전자 도메인 분석 결과이다.
도 5는 본 발명의 점보박테리오파지 PALS2 유래 엔도라이신 LysPALS21과 LysPALS22의 단백질 정제 결과이다.
도 6은 본 발명의 점보박테리오파지 PALS2 유래 엔도라이신 LysPALS21의 농도에 따른 황색포도상구균 사멸효과를 나타낸 결과이다.
도 7은 본 발명의 점보박테리오파지 PALS2 유래 엔도라이신 LysPALS22의 황색포도상구균 사멸효과 및 LysPALS21에 대한 보조효과를 나타낸 결과이다.
도 8은 본 발명의 점보박테리오파지 PALS2 유래 엔도라이신 LysPALS21의 황색포도상구균에 대한 용균활성에 pH(A), NaCl 농도(B), 열(C), 양이온(D)이 미치는 영향에 관한 실험결과이다.
도 9는 본 발명의 점보박테리오파지 PALS2 유래 엔도라이신 LysPALS21 다양한 종의 엔테로코쿠스 페칼리스(Enterococcus faecalis)에 대한 용균효과를 나타낸 결과이다. 비교를 위해 이전 특허등록된 엔도라이신들(LysSA11, LysCSA13)을 사용하였다.
도 10은 본 발명의 점보박테리오파지 PALS2 유래 엔도라이신 LysPALS21의 혈액환경에서 황색포도상구균 제거능을 나타낸 결과이다.1 is an electron micrograph of the jumbo bacteriophage PALS2 of the present invention.
2 is a genome analysis result of jumbo bacteriophage PALS2 of the present invention.
3 is a result showing the lytic activity against Staphylococcus aureus of the jumbo bacteriophage PALS2 of the present invention.
4 is a result of analyzing the gene domains of LysPALS21 and LysPALS22 endolysin derived from jumbo bacteriophage PALS2 of the present invention.
5 is a protein purification result of LysPALS21 and LysPALS22 endolysin derived from jumbo bacteriophage PALS2 of the present invention.
Figure 6 is a result showing the Staphylococcus aureus killing effect according to the concentration of the endolysin LysPALS21 derived from the jumbo bacteriophage PALS2 of the present invention.
7 is a result showing the Staphylococcus aureus killing effect and the auxiliary effect on LysPALS21 of LysPALS22, the endolysin LysPALS22 derived from the jumbo bacteriophage PALS2 of the present invention.
8 is an experimental result regarding the effect of pH (A), NaCl concentration (B), heat (C), and cation (D) on the lytic activity of the jumbo bacteriophage PALS2-derived endolysin LysPALS21 against Staphylococcus aureus of the present invention. .
9 is a jumbo bacteriophage PALS2-derived endolysin LysPALS21 of the present invention Enterococcus faecalis of various species of Enterococcus faecalis ( Enterococcus faecalis ) is a result showing the lytic effect. For comparison, previously patented endolysins (LysSA11, LysCSA13) were used.
10 is a result showing the Staphylococcus aureus removal ability of the jumbo bacteriophage PALS2-derived endolysin LysPALS21 of the present invention in the blood environment.
황색포도상구균(Staphylococcus aureus)은 그람 양성균으로, 인간과 동물에 감염하여 수술 후 감염, 농양, 심장 내막염 및 독소 증후군 등의 심각한 질병을 유도하거나 TSST-1, EF, 알파, 베타, 델타 독소 등 열에 강한 독소를 생성하기 때문에 쉽게 사멸되지 않고 심각한 식중독을 유발한다. 황색포도상구균을 제어하기 위해 항생제가 주로 사용되어 왔지만, 항생제의 광범위한 사용은 항생제에 대해 저항성을 보이는 세균(예: MSSA 등)을 발생시키는 문제를 야기했다. 이를 극복하기 위한 대안으로 기존 항생제의 여러 단점들을 보완할 수 있는 새로운 황색포도상구균의 생물학적 방제제를 개발하는 것이 필요한 실정이다.Staphylococcus aureus is a gram-positive bacterium that infects humans and animals and induces serious diseases such as postoperative infections, abscesses, endocarditis and toxin syndrome, or heat-reducing TSST-1, EF, alpha, beta, and delta toxins. Because it produces a strong toxin, it is not easily killed and causes serious food poisoning. Although antibiotics have been mainly used to control Staphylococcus aureus, the widespread use of antibiotics has created a problem of generating bacteria that are resistant to antibiotics (eg MSSA, etc.). As an alternative to overcoming this, it is necessary to develop a new Staphylococcus aureus biological control agent that can compensate for various shortcomings of existing antibiotics.
이에 본 발명에서는 다양한 질병을 일으키는 황색포도상구균을 제어하기 위하여 황색포도상구균 용균 활성이 있는 것을 특징으로 하는 박테리오파지 PALS2(KACC97035P), 서열번호 3의 아미노산 서열로 구성된 엔도라이신 LysPALS21 또는 서열번호 5의 아미노산 서열로 구성된 엔도라이신 LysPALS22를 제공한다.Accordingly, in the present invention, bacteriophage PALS2 (KACC97035P), which has a Staphylococcus aureus lytic activity to control Staphylococcus aureus causing various diseases, endolysin LysPALS21 consisting of the amino acid sequence of SEQ ID NO: 3 or amino acid sequence of SEQ ID NO: 5 Provides an endolysin LysPALS22 composed of.
본 발명의 박테리오파지 PASL2(KACC97035P)는 유전체 크기가 200kbp 이상으로, 황색포도상구균 파지로는 최초로 보고된 점보파지이다. 염기서열 상동성을 BlastN, BlastP 프로그램을 이용하여 조사한 결과, 박테리오파지 PALS2는 등록된 황색포도상구균 파지들과의 상동성이 매우 낮아 신규한 박테리오파지라고 볼 수 있다. 점보파지의 특성으로 언급되는 바와 같이 본 발명의 박테리오파지 PASL2(KACC97035P) 및 그것 유래의 엔도라이신은 넓은 항균활성 범위를 가진다. The bacteriophage PASL2 (KACC97035P) of the present invention has a genome size of 200 kbp or more, and is a jumbo phage reported for the first time as a Staphylococcus aureus phage. As a result of investigating the nucleotide sequence homology using the BlastN, BlastP program, the bacteriophage PALS2 can be considered a novel bacteriophage with very low homology with the registered Staphylococcus aureus phages. As mentioned as a characteristic of jumbo phage, the bacteriophage PASL2 (KACC97035P) of the present invention and endolysin derived therefrom have a wide range of antimicrobial activity.
또한, 본 발명의 박테리오파지 PASL2(KACC97035P)는 기존의 다른 박테리오파지와 달리 엔도라이신을 두 개(LysPALS21, LysPALS22) 가진다는 점에 특징이 있다. 염기서열 상동성을 BlastN, BlastP 프로그램을 이용하여 조사한 결과, LysPALS21의 경우 등록된 황색포도상구균 엔도라이신들과 30%대의 낮은 상동성을 보였으며, LysPALS22의 경우에도 50%가 되지 않는 낮은 상동성을 나타냈다.In addition, the bacteriophage PASL2 (KACC97035P) of the present invention is characterized in that it has two (LysPALS21, LysPALS22) endolysins, unlike other bacteriophages of the present invention. As a result of investigating the nucleotide sequence homology using the BlastN and BlastP programs, LysPALS21 showed low homology with the registered Staphylococcus aureus endolysins in the 30% range, and LysPALS22 showed low homology of less than 50%. showed
한편, 본 발명의 박테리오파지 PASL2(KACC97035P), 엔도라이신 LysPALS21 또는 LysPALS22는 황색포도상구균을 숙주로 하여 수행한 실험에서 플라크를 형성 혹은 세균부유액의 탁도를 감소시켜 황색포도상구균을 용해(lysis)시키는 것을 확인할 수 있었으며, 상기 황색포도상구균은, 일예로 메티실린 저항성 황색포도상구균(Methicillin-resistant S. aureus, MRSA) 또는 메티실린 감수성 황색포도상구균(Methicillin-sensitivity S. aureus, MSSA)인 것일 수 있다. On the other hand, it is confirmed that the bacteriophage PASL2 (KACC97035P), endolysin LysPALS21 or LysPALS22 of the present invention forms a plaque in an experiment performed with Staphylococcus aureus as a host or reduces the turbidity of the bacterial suspension to dissolve Staphylococcus aureus (lysis). It could be, and the Staphylococcus aureus may be, for example, methicillin-resistant S. aureus (MRSA) or methicillin-sensitive S. aureus (MSSA).
한편, 본 발명의 엔도라이신 LysPALS21은 혈액 내에서도 효과적으로 황색포도상구균에 대해 용균 활성능을 가진다. 또한, 본 발명의 엔도라이신 LysPALS21은 그람양성균인 엔테로코쿠스 페칼리스(Enterococcus faecalis)의 다양한 범위에서도 높은 용균활성을 나타내는 것을 확인할 수 있었으며, 이는 기존의 다른 엔도라이신에서 나타나지 않은 차별화된 특징이다.On the other hand, the endolysin LysPALS21 of the present invention has a lytic activity against Staphylococcus aureus effectively even in blood. In addition, it was confirmed that the endolysin LysPALS21 of the present invention exhibited high lytic activity in various ranges of the Gram-positive bacterium Enterococcus faecalis , which is a differentiated feature not shown in other existing endolysins.
또한, 본 발명은 박테리오파지 PALS2(KACC97035P), 서열번호 3의 아미노산 서열로 구성된 엔도라이신 LysPALS21 또는 서열번호 5의 아미노산 서열로 구성된 엔도라이신 LysPALS22 중에서 선택되는 어느 하나 이상을 포함하는 것을 특징으로 하는 황색포도상구균 감염 질환의 개선용 식품 조성물을 제공한다. 본 발명의 식품 조성물은 바람직하게 육류, 곡류, 카페인 음료, 일반음료, 초콜릿, 빵류, 스낵류, 과자류, 피자, 젤리, 면류, 껌류, 아이스크림류, 알코올성 음료, 술, 비타민 복합제 및 그 밖의 건강보조식품류 중 선택되는 어느 하나에 첨가되는 것이 좋으나, 이에 한정되는 것은 아니다.In addition, the present invention is bacteriophage PALS2 (KACC97035P), endolysin LysPALS21 consisting of the amino acid sequence of SEQ ID NO: 3, or endolysin LysPALS22 consisting of the amino acid sequence of SEQ ID NO: 5 Staphylococcus aureus, characterized in that it comprises at least one selected from It provides a food composition for improving infectious diseases. The food composition of the present invention is preferably meat, grain, caffeinated beverage, general beverage, chocolate, bread, snack, confectionery, pizza, jelly, noodles, gum, ice cream, alcoholic beverage, alcohol, vitamin complex and other health supplements. It is preferably added to any one selected from, but is not limited thereto.
한편, 본 발명의 박테리오파지 PASL2(KACC97035P), 엔도라이신 LysPALS21 또는 LysPALS22는 바람직하게 식품 첨가제 대비 0.1~20중량% 포함되는 것이 좋다. 0.1중량% 미만일 경우에는 그 효과가 미비하고, 20중량%를 초과하는 경우에는 사용량 대비 효과 증가가 미미하여 비경제적이다.On the other hand, the bacteriophage PASL2 (KACC97035P), endolysin LysPALS21 or LysPALS22 of the present invention is preferably contained in 0.1 to 20% by weight compared to food additives. When it is less than 0.1% by weight, the effect is insignificant, and when it exceeds 20% by weight, the increase in the effect is insignificant compared to the amount used, which is uneconomical.
또한, 본 발명은 박테리오파지 PALS2(KACC97035P), 서열번호 3의 아미노산 서열로 구성된 엔도라이신 LysPALS21 또는 서열번호 5의 아미노산 서열로 구성된 엔도라이신 LysPALS22 중에서 선택되는 어느 하나 이상을 포함하는 것을 특징으로 하는 황색포도상구균 감염 질환의 예방 또는 치료용 약학 조성물을 제공한다.In addition, the present invention is bacteriophage PALS2 (KACC97035P), endolysin LysPALS21 consisting of the amino acid sequence of SEQ ID NO: 3, or endolysin LysPALS22 consisting of the amino acid sequence of SEQ ID NO: 5 Staphylococcus aureus, characterized in that it comprises at least one selected from It provides a pharmaceutical composition for preventing or treating an infectious disease.
본 발명의 약학 조성물에 포함되는 박테리오파지 PASL2(KACC97035P), 엔도라이신 LysPALS21 또는 LysPALS22는 상술한 바와 같이 황색포도상구균을 특이적으로 사멸시킬 수 있어, 황색포도상구균에 의해 유발된 다양한 질환, 예컨대 유방염, 피부염, 패혈증, 화농성 질환, 식중독, 폐렴, 골수염, 농가진, 균혈증, 심내막염 및 장염 등에 관한 치료에 효과를 나타낸다. 이러한 목적의 조성물에는 추가적 치료의 효과를 얻기 위하여 이미 황색포도상구균에 대해 항균 활성이 입증된 성분이 추가로 포함될 수 있다.Bacteriophage PASL2 (KACC97035P), endolysin LysPALS21 or LysPALS22 contained in the pharmaceutical composition of the present invention can specifically kill Staphylococcus aureus as described above, and various diseases caused by Staphylococcus aureus, such as mastitis, dermatitis, , sepsis, purulent diseases, food poisoning, pneumonia, osteomyelitis, impetigo, bacteremia, endocarditis and enteritis, etc. are effective in treatment. The composition for this purpose may further contain ingredients that have already demonstrated antibacterial activity against Staphylococcus aureus in order to obtain an additional therapeutic effect.
본 발명의 약학 조성물에 포함되는 박테리오파지 PASL2(KACC97035P), 엔도라이신 LysPALS21 또는 LysPALS22의 함량은, 사용방법, 복용자의 상태에 따라 바람직하게 조절하는 것이 좋다. 본 발명의 약학조성물에서 박테리오파지 PASL2(KACC97035P), 엔도라이신 LysPALS21 또는 LysPALS22의 함량은 약학조성물 대비 0.01~5중량%일 수 있으나, 반드시 이에 한정되는 것은 아니다. 그러나 그 함량이 0.01중량% 미만일 경우 면역 효과가 미미할 수 있으며, 5중량%를 초과하는 경우에는 사용량 대비 효과 상승률이 낮아 비경제적일 수 있다.The content of bacteriophage PASL2 (KACC97035P), endolysin LysPALS21 or LysPALS22 contained in the pharmaceutical composition of the present invention is preferably adjusted according to the method of use and the condition of the user. The content of bacteriophage PASL2 (KACC97035P), endolysin LysPALS21 or LysPALS22 in the pharmaceutical composition of the present invention may be 0.01 to 5% by weight compared to the pharmaceutical composition, but is not necessarily limited thereto. However, if the content is less than 0.01% by weight, the immune effect may be insignificant, and if it exceeds 5% by weight, the effect increase rate is low compared to the amount used, and thus it may be uneconomical.
한편, 본 발명의 약학 조성물은 유효성분 이외에 약제학적으로 허용가능한 담체, 희석제 또는 부형제를 더욱 포함할 수 있다. 사용 가능한 담체, 부형제 또는 희석제로는, 락토즈, 덱스트로즈, 수크로즈, 솔비톨, 만니톨, 자이리톨, 에리스리톨, 말티톨, 전분, 아카시아 고무, 알지네이트, 젤라틴, 칼슘 포스페이트, 칼슘 설리케이트, 셀룰로즈, 메틸 셀룰로즈, 미정질 셀룰로즈, 폴리비닐피롤리돈, 물, 메틸하이드록시벤조에이트, 프로필하이드록시벤조에이트, 탈크, 마그네슘 스테아레이트 및 광물류가 있으며, 이들은 1종 이상 사용될 수 있다. 또한, 예방 및 치료제가 약제일 경우 충진제, 항응집제, 윤활제, 습윤제, 향료, 유화제 또는 방부제 등이 추가로 포함될 수 있다.On the other hand, the pharmaceutical composition of the present invention may further include a pharmaceutically acceptable carrier, diluent or excipient in addition to the active ingredient. Usable carriers, excipients or diluents include lactose, dextrose, sucrose, sorbitol, mannitol, xylitol, erythritol, maltitol, starch, acacia gum, alginate, gelatin, calcium phosphate, calcium sulfate, cellulose, methyl cellulose. , microcrystalline cellulose, polyvinylpyrrolidone, water, methylhydroxybenzoate, propylhydroxybenzoate, talc, magnesium stearate and minerals, and one or more of these may be used. In addition, when the prophylactic and therapeutic agents are pharmaceuticals, fillers, anti-aggregants, lubricants, wetting agents, fragrances, emulsifiers, or preservatives may be additionally included.
한편, 본 발명의 약학 조성물의 제형은 사용방법에 따라 바람직한 형태일 수 있으며, 특히 포유동물에 투여된 후 활성 성분의 신속, 지속 또는 지연된 방출을 제공할 수 있도록 당업계에 공지된 방법을 채택하여 제형화 하는 것이 좋다. 구체적인 제형의 예로는 경고제 (PLASTERS), 과립제 (GRANULES), 로션제(LOTIONS), 리니멘트제(LINIMENTS), 리모나데제 (LEMONADES), 방향수제 (AROMATIC WATERS), 산제 (POWDERS), 시럽제 (SYRUPS), 안연고제 (OPHTHALMIC OINTMENTS), 액제 (LIQUIDS FORMULATIONS), 에어로솔제 (AEROSOLS), 엑스제 (EXTRACTS), 엘릭실제(ELIXIRS), 연고제 (OINTMENTS), 유동엑스제 (FLUIDEXTRACTS), 유제 (EMULSIONS), 현탁제 (SUSPENSIONS), 전제 (DECOCTIONS), 침제 (INFUSIONS), 점안제 (EYE DROPS), 정제 (TABLETS), 좌제 (SUPPOSITORIES), 주사제 (INJECTIONS), 주정제 (SPIRITS), 카타플라스마제 (CATAPLASMA), 캅셀제 (CAPSULES), 크림제 (CREAMS), 트로키제 (TROCOES), 팅크제 (TINCTURES), 파스타제 (PASTES), 환제 (PILLS), 연질 또는 경질 젤라틴 캅셀 중 선택되는 어느 하나일 수 있다.On the other hand, the dosage form of the pharmaceutical composition of the present invention may be in a preferred form depending on the method of use, and in particular, by adopting a method known in the art to provide rapid, sustained or delayed release of the active ingredient after administration to a mammal. It is good to formulate. Examples of specific formulations include warning agents (PLASTERS), granules (GRANULES), lotions (LOTIONS), LINIMENTS (LINIMENTS), limonades (LEMONADES), perfumes (AROMATIC WATERS), powders (POWDERS), syrups ( SYRUPS), OPHTHALMIC OINTMENTS, LIQUIDS FORMULATIONS, aerosols (AEROSOLS), extracts (EXTRACTS), ELIXIRS, ointments (OINTMENTS), fluid extracts (FLUIDEXTRACTS), emulsions (EMULSIONS) , Suspension (SUSPENSIONS), Prescription (DECOCTIONS), Injecting (INFUSIONS), Eye Drops (EYE DROPS), Tablets (TABLETS), Suppositories (SUPPOSITORIES), Injections (INJECTIONS), Alcoholic Tablets (SPIRITS), Cataplasma Agents (CATAPLASMA) , capsules (CAPSULES), creams (CREAMS), troches (TROCOES), tinctures (TINCTURES), pastas (PASTES), pills (PILLS), may be any one selected from soft or hard gelatin capsules.
한편, 본 발명 약학조성물의 투여량은 투여방법, 복용자의 연령, 성별 및 체중 등을 고려하여 결정하는 것이 좋다. 일 예로, 본 약학조성물은 유효성분을 기준으로 하였을 때 1일 0.1~100mg/kg (체중)으로 1회 이상 투여 가능하다. 그러나 상기의 투여량은 예시하기 위한 일 예에 불과하며, 복용자의 상태에 의해 변화될 수 있다.On the other hand, the dosage of the pharmaceutical composition of the present invention is preferably determined in consideration of the administration method, the age, sex and weight of the user. For example, the pharmaceutical composition can be administered at least once per day at 0.1-100 mg/kg (body weight) based on the active ingredient. However, the above dosage is only an example for illustration, and may be changed depending on the state of the user.
또한, 본 발명은 박테리오파지 PALS2(KACC97035P), 서열번호 3의 아미노산 서열로 구성된 엔도라이신 LysPALS21 또는 서열번호 5의 아미노산 서열로 구성된 엔도라이신 LysPALS22 중에서 선택되는 어느 하나 이상을 포함하는 것을 특징으로 하는 사료 조성물을 제공한다. 상기 사료 조성물에 있어서, 조성물 총 중량에 대하여 상기 박테리오파지 PASL2(KACC97035P), 엔도라이신 LysPALS21 또는 LysPALS22를 0.001~10중량% 함유할 수 있다. 이는 그 함량이 조성물 총 중량에 대해 0.001중량% 미만이면 그 용균 효과를 충분히 발휘할 수 없으며, 1.0중량%를 초과하는 경우에는 제형의 안정성 및 안전성에 문제를 야기하기 때문이다.In addition, the present invention provides a feed composition comprising at least one selected from bacteriophage PALS2 (KACC97035P), endolysin LysPALS21 consisting of the amino acid sequence of SEQ ID NO: 3, or endolysin LysPALS22 consisting of the amino acid sequence of SEQ ID NO: 5 to provide. In the feed composition, the bacteriophage PASL2 (KACC97035P), endolysin LysPALS21 or LysPALS22 may contain 0.001 to 10% by weight based on the total weight of the composition. This is because if the content is less than 0.001% by weight based on the total weight of the composition, the lytic effect cannot be sufficiently exhibited, and when it exceeds 1.0% by weight, it causes problems in the stability and safety of the formulation.
한편, 본 발명의 상기 조성물은 통상의 배합사료에 섞어서 경구투여의 방법으로 급여하며, 계속 투여 또는 과다 투여시에도 면역저하 등의 내성이나 부작용의 문제가 거의 없다.On the other hand, the composition of the present invention is mixed with a conventional compound feed and fed by oral administration, and there is almost no problem of tolerance or side effects such as immunosuppression even when continuously administered or overdosed.
또한, 본 발명은 박테리오파지 PALS2(KACC97035P), 서열번호 3의 아미노산 서열로 구성된 엔도라이신 LysPALS21 또는 서열번호 5의 아미노산 서열로 구성된 엔도라이신 LysPALS22 중에서 선택되는 어느 하나 이상을 포함하는 것을 특징으로 하는 세정제 조성물을 제공한다. 본 발명의 세정제 조성물은 세정제 조성물에 통상적으로 이용되는 성분들을 추가로 더 포함할 수 있으며, 예컨대 안정화제, 용해화제 및 향료와 같은 통상적인 보조제, 그리고 담체를 포함할 수 있다.In addition, the present invention provides a cleaning composition comprising at least one selected from bacteriophage PALS2 (KACC97035P), endolysin LysPALS21 consisting of the amino acid sequence of SEQ ID NO: 3, or endolysin LysPALS22 consisting of the amino acid sequence of SEQ ID NO: 5 to provide. The cleaning composition of the present invention may further include components commonly used in cleaning compositions, for example, conventional adjuvants such as stabilizers, solubilizers and fragrances, and carriers.
본 발명의 세정제 조성물의 제형이 페이스트, 크림 또는 겔인 경우에는 담체 성분으로서 동물성유, 식물성유, 왁스, 파라핀, 전분, 트라칸트, 셀룰로오스 유도체, 폴리에틸렌 글리콜, 실리콘, 벤토나이트, 실리카, 탈크 또는 산화아연 등이 이용될 수 있다.When the formulation of the cleaning composition of the present invention is a paste, cream or gel, animal oil, vegetable oil, wax, paraffin, starch, tracanth, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide, etc. this can be used
본 발명의 세정제 조성물의 제형이 용액 또는 유탁액인 경우에는 담체 성분으로서 용매, 용해화제 또는 유탁화제가 이용되고, 예컨대 물, 에탄올, 이소프로판올, 에틸 카보네이트, 에틸 아세테이트, 벤질 알코올, 벤질 벤조에이트, 프로필렌글리콜, 1,3-부틸글리콜 오일, 글리세롤 지방족 에스테르, 폴리에틸렌글리콜 또는 소르비탄의 지방산 에스테르가 이용될 수 있다.When the formulation of the cleaning composition of the present invention is a solution or emulsion, a solvent, solubilizer or emulsifier is used as a carrier component, for example, water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene Glycol, 1,3-butylglycol oil, glycerol aliphatic ester, polyethylene glycol or fatty acid ester of sorbitan may be used.
본 발명의 세정제 조성물의 제형이 현탁액인 경우에는 담체 성분으로서 물, 에탄올 또는 프로필렌글리콜과 같은 액상의 희석제, 에톡실화 이소스테아릴 알코올, 폴리옥시에틸렌 소르비톨 에스테르 및 폴리옥시에틸렌 소르비탄 에스테르와 같은 현탁제, 미소 결정성 셀룰로오스, 알루미늄 메타히드록시드, 벤토나이트, 아가 또는 트라칸트 등이 이용될 수 있다When the formulation of the detergent composition of the present invention is a suspension, as a carrier component, a liquid diluent such as water, ethanol or propylene glycol, ethoxylated isostearyl alcohol, a suspending agent such as polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester , microcrystalline cellulose, aluminum metahydroxide, bentonite, agar or tracanth may be used.
본 발명의 세정제 조성물의 제형이 스프레이인 경우에는 담체 성분으로서 락토스, 탈크, 실리카, 알루미늄 히드록시드, 칼슘 실리케이트 또는 폴리아미드 파우더가 이용될 수 있고, 특히 스프레이인 경우에는 추가적으로 클로로플루오로히드로카본, 프로판/부탄 또는 디메틸 에테르와 같은 추진체를 포함할 수 있다.When the formulation of the cleaning composition of the present invention is a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component, and in particular, in the case of a spray, additional chlorofluorohydrocarbon, propellants such as propane/butane or dimethyl ether.
본 발명의 세정제 조성물의 제형이 계면활성제 함유 클렌징인 경우에는 담체 성분으로서 지방족 알코올 설페이트, 지방족 알코올 에테르 설페이트, 설포숙신산 모노에스테르, 이세티오네이트, 이미다졸리늄 유도체, 메틸타우레이트, 사르코시네이트, 지방산 아미드 에테르 설페이트, 알킬아미도베타인, 지방족 알코올, 지방산 글리세리드, 지방산 디에탄올아미드, 식물성 유, 라놀린 유도체 또는 에톡실화 글리세롤 지방산 에스테르 등이 이용될 수 있다.When the formulation of the detergent composition of the present invention is surfactant-containing cleansing, aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyl taurate, sarcosinate, Fatty acid amide ether sulfate, alkylamidobetaine, fatty alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, lanolin derivative or ethoxylated glycerol fatty acid ester and the like can be used.
의료용 세정제로 사용될 경우에는 스프레이 형태로 바이오필름 형성을 막고자 하는 부분, 즉 인공관절, 도뇨관 표면, 내시경 또는 상처에 뿌리는 방법이 가능하다. 또한, 손을 사용한 세척은 물론이고 초음파 세척기 및 자동 세척기를 이용할 수도 있다. 또, 의료용 장치를 의료용세정제에 담구는 방법도 가능하다.When used as a medical cleaning agent, it is possible to spray on the part to prevent biofilm formation in the form of a spray, that is, an artificial joint, the surface of a catheter, an endoscope, or a wound. In addition, in addition to washing by hand, an ultrasonic washing machine and an automatic washing machine may be used. In addition, a method of immersing the medical device in a medical cleaning agent is also possible.
본 발명의 세정제 조성물은 조리 장소 및 조리 설비의 소독제로 유용하게 사용될 수 있다. 본 발명에서 사용되는 의료용 세정제 및 환경정화제용 조성물에서의 박테리오파지 PALS2(KACC97035P), 엔도라이신 LysPALS21 또는 엔도라이신 LysPALS22의 유효 용량은 보통으로 숙련된 당업자에 의해서 간단한 사전 조사를 거쳐 용이하게 결정될 수 있다. 특정 용량은 응용하고자 하는 분야 및 적용방법에 의해 좌우될 것이다. 본 발명의 조성물은 박테리오파지의 경우 일반적으로, 1×103~1×1012 pfu/㎖의 박테리오파지를 포함하며, 바람직하게는 1×108~1×1010 pfu/㎖의 박테리오파지를 포함하고, 엔도라이신의 경우 0.001%(w/v)~0.1%(w/v), 바람직하게는 0.002%(w/v)~0.01%(w/v), 가장 바람직하게는 0.005%(w/v)를 포함한다. 또한, 본 발명에 개시된 박테리오파지 PALS2(KACC97035P), 엔도라이신 LysPALS21 또는 엔도라이신 LysPALS22는 상호 보완적으로 혼용될 수도 있다.The cleaning composition of the present invention can be usefully used as a disinfectant for cooking places and cooking equipment. The effective dose of the bacteriophage PALS2 (KACC97035P), endolysin LysPALS21 or endolysin LysPALS22 in the composition for medical detergents and environmental purifiers used in the present invention can be easily determined through simple preliminary investigation by those skilled in the art. The specific dosage will depend on the field and method of application in which it is intended. In the case of bacteriophage, the composition of the present invention generally includes 1×10 3 to 1×10 12 pfu/ml of bacteriophage, preferably 1×10 8 to 1×10 10 pfu/ml of bacteriophage, For endolysin, 0.001% (w/v) to 0.1% (w/v), preferably 0.002% (w/v) to 0.01% (w/v), most preferably 0.005% (w/v) includes In addition, the bacteriophage PALS2 (KACC97035P), endolysin LysPALS21 or endolysin LysPALS22 disclosed in the present invention may be used interchangeably.
이하, 본 발명의 구성을 하기 실시예 및 실험예를 통해 구체적으로 설명하고자 한다. 다만, 본 발명의 권리범위가 하기 실시예 및 실험예에만 한정되는 것은 아니고, 그와 등가의 기술적 사상의 변형까지를 포함한다.Hereinafter, the configuration of the present invention will be described in detail through the following examples and experimental examples. However, the scope of the present invention is not limited only to the following examples and experimental examples, and includes modifications of technical ideas equivalent thereto.
[실시예 1: 본 발명의 점보박테리오파지 PALS2 분리, 동정 및 유전체 분석][Example 1: Isolation, identification and genome analysis of jumbobacteriophage PALS2 of the present invention]
(1) 박테리오파지의 분리(1) Isolation of bacteriophages
황색포도상구균에 대한 박테리오파지를 분리하기 위해, 조류분변 샘플로부터 박테리오파지 분리실험을 수행하였다. 조류분변을 SM 완충용액에서 균질화 과정을 거친 후, 10,000g 에서 5분간 원심분리하고, 상등액을 0.22 μm 막필터를 통해 여과시켜 잔여물을 제거한 용액을 만들었다. 이 여과액 0.1 mL와 TSB배지(Tryptic Soy Broth)에서 12시간 이상 배양한 황색포도상구균(Staphylococcus arueus) 0.1 mL의 현탁액을 섞어 주었다. 37℃에서 12시간동안 진탕 배양한 후, 이를 4℃에서 최대 속도로 5분간 원심분리하여 상등액을 취하고 이를 0.22 μm 막필터로 여과하였다. 0.1 ml의 여과액과 8시간 이상 배양한 세균 0.1 ml의 현탁액 그리고 1M 염화마그네슘과 1M 염화칼슘을 각각 0.025 ml를 섞어 주었다. In order to isolate the bacteriophage for Staphylococcus aureus, a bacteriophage separation experiment was performed from the algal feces sample. After the algal feces were homogenized in SM buffer, centrifuged at 10,000 g for 5 minutes, and the supernatant was filtered through a 0.22 μm membrane filter to remove the residue. 0.1 mL of this filtrate and a suspension of 0.1 mL of Staphylococcus aureus cultured for 12 hours or more in TSB medium (Tryptic Soy Broth) were mixed. After culturing with shaking at 37°C for 12 hours, it was centrifuged at 4°C at maximum speed for 5 minutes to obtain a supernatant and filtered through a 0.22 μm membrane filter. 0.1 ml of the filtrate, a suspension of 0.1 ml of bacteria cultured for more than 8 hours, and 0.025 ml of 1M magnesium chloride and 1M calcium chloride were mixed with each other.
이 혼합액을 TSB에 낮은 농도의 아가를 섞은 소프트 아가 배지(0.4% TSB soft agar) 5ml 와 함께 섞어서 1.5% TSA 배지를 포함하는 플레이트에 부었다. 이후, 상기 플레이트를 37℃에서 12시간 동안 배양하였다. 일정시간 경과 후, 목적하는 박테리오파지가 플레이트 상에 독립되고 투명한 용균반으로 관찰되었다. 용균반의 크기는 일반적으로 관찰되는 용균반보다 작았기에, 크기가 큰 박테리오파지(점보박테리오파지)일거라 추측하고, 이를 수월하게 분리해내기 위해 이후 모든 배양에 소프트아가는 0.3% TSB soft agar로, 온도는 30℃ 로 낮추어 진행하였다. 상기 용균반 영역을 백금 루프를 이용하여 분리해 낸 다음, 새로운 세균 배양액에 넣어 30℃에서 배양하였는데, 배양액이 맑아짐을 관찰할 수 있었다. 이후 배양액을 원심분리하고, 상등액을 취해 0.22 μm 막필터를 통해 여과시켜 용해물에 남아있는 모든 세균을 제거하고, 여과액만을 취하였다. 이때, 상기 여과액은 박테리오파지만을 포함한다. 상기의 과정을 통해 얻은 박테리오파지 용액을 가지고, 아가 배지 상에서 다르게 희석하고 주입하여 용균반의 재분리를 3회 수행하였고, 이와 같은 일련의 과정을 통해 순수한 박테리오파지 PALS2를 얻을 수 있었다.This mixture was mixed with 5 ml of soft agar medium (0.4% TSB soft agar) in which TSB was mixed with low concentration agar, and poured onto a plate containing 1.5% TSA medium. Thereafter, the plate was incubated at 37° C. for 12 hours. After a certain period of time, the desired bacteriophage was observed as an independent and transparent plaque on the plate. Since the size of the plaque is smaller than the commonly observed plaque, it is assumed that it is a large bacteriophage (jumbo bacteriophage). It proceeded by lowering to 30 ℃. After separating the gyunban region using a platinum loop, it was put into a new bacterial culture medium and cultured at 30° C., and it was observed that the culture medium was clear. Then, the culture solution was centrifuged, and the supernatant was filtered through a 0.22 μm membrane filter to remove all bacteria remaining in the lysate, and only the filtrate was collected. At this time, the filtrate contains only bacteriophage. With the bacteriophage solution obtained through the above process, the re-separation of the lysate was performed three times by diluting and injecting differently on an agar medium, and through this series of processes, pure bacteriophage PALS2 could be obtained.
(2) 박테리오파지 PALS2의 형태 관찰 및 분류(2) Morphological observation and classification of bacteriophage PALS2
박테리오파지 PALS2의 형태를 관찰하기 위해 염화세슘(CsCl) 밀도 구배법(밀도: 0.39g/㎖, 0.6 g/㎖, 0.67 g/㎖ 및 0.95 g/㎖)을 이용한 원심분리(25,000 rpm, 2시간, 4℃)를 통하여 박테리오파지를 정제한 다음, 투과전자현미경을 사용하여 점보박테리오파지의 형태를 관찰하였다. Cesium chloride (CsCl) density gradient method (density: 0.39 g / ml, 0.6 g / ml, 0.67 g / ml and 0.95 g / ml) to observe the morphology of the bacteriophage PALS2 centrifugation (25,000 rpm, 2 hours, After purifying the bacteriophage through 4 ℃), the shape of the jumbo bacteriophage was observed using a transmission electron microscope.
이를 상세히 설명하자면, 정제된 박테리오파지를 구리 격자(copper grid)에 올리고, 2% 액상 우라닐 아세테이트(Uranyl acetate)로 음성 염색(negative staining)을 하고 건조시켰다. 염색된 시료를 120kV의 전압으로 에너지 여과 투과 전자현미경(LIBRA 120, Carl Zeiss)을 이용하여 관찰하였다. 그 결과, 박테리오파지를 모양으로 분류하는 기준으로 보았을 때, 도 1과 같이 박테리오파지 PALS2는 약 110nm의 육각형머리를 가지고 201~ 230 nm의 긴 수축성 꼬리(a long contractile tail)와 시스(sheath)를 갖는, 마이오비리대(Myoviriade)로 분류되었다.To explain this in detail, the purified bacteriophage was placed on a copper grid, and negative staining was performed with 2% liquid uranyl acetate (Uranyl acetate) and dried. The stained sample was observed using an energy filtration transmission electron microscope (LIBRA 120, Carl Zeiss) at a voltage of 120 kV. As a result, when viewed as a criterion for classifying bacteriophages by shape, bacteriophage PALS2 has a hexagonal head of about 110 nm and a long contractile tail of 201 to 230 nm as shown in FIG. 1 (a long contractile tail) and a sheath (sheath), It was classified as Myoviriade .
(3) 박테리오파지 PALS2의 유전체(genome) 분석(3) Genome analysis of bacteriophage PALS2
*박테리오파지 PALS2의 유전체를 분석하였다. PALS2의 유전체는 페놀-클로로포름(phenol-chloroform) 추출법으로 추출 및 정제하였다. 정제된 DNA의 뉴클레오티드 서열 분석은 ‘Illumina Miseq'을 이용하여 진행되었고, 각 리드(read)의 어셈블리(assembly)는 ‘CLC Genomics Workbench 10.0.1'을 이용하여 수행되었다. 유전체가 갖고 있는 ORF의 위치는 ‘Glimmer 3.02, GeneMarkS, RAST'를 이용하여 예측하였다. 또한, ‘NCBI'의 ‘BLASTP'를 통해 각 ORF에서 만들어지는 단백질의 기능을 예측하였다. 예측된 ORF의 기능에 따라 각 ORF에 적절한 이름을 명명(annotation)하였고, 기능이 파악되지 않는 ORF는 모두 가설 단백질(hypothetical protein)이라 명명하였다. ORF의 위치와 기능 등은 모두 ‘CLC Genomic Workbench 6'을 통해 정리하였다.* The genome of the bacteriophage PALS2 was analyzed. The genome of PALS2 was extracted and purified by the phenol-chloroform extraction method. Nucleotide sequence analysis of the purified DNA was performed using 'Illumina Miseq', and assembly of each read was performed using 'CLC Genomics Workbench 10.0.1'. The position of the ORF in the genome was predicted using ‘Glimmer 3.02, GeneMarkS, RAST’. In addition, the function of the protein produced in each ORF was predicted through 'BLASTP' of 'NCBI'. Appropriate names for each ORF were annotated according to the predicted ORF function, and all ORFs whose functions were not identified were named hypothetical proteins. The location and function of ORF were all organized through ‘CLC Genomic Workbench 6’.
실험결과, 박테리오파지 PALS2 유전체(genome)는 총 길이 268,748 bp, G+C 함량 24.66%의 염기 서열을 갖는 것으로 나타났다(서열번호 1에 염기서열 기재). 따라서 상기의 박테리오파지 PALS2는 꼬리를 갖고 유전체 사이즈가 200kbp 이상인 '점보파지'로 분류된다 (Yuan, Y. & Gao, M. 2017. Jumbo bacteriophages: an overview. Front. Microbiol. 8, 403). ORF 분석 결과, 도 2와 같이 총 279개의 ORF가 예측되었고, 일반적으로 크기가 작은 박테리오파지의 경우 숙주균에 의존하는 유전자인 DNA 및 RNA polymerase 여러 개를 직접 소유하고 있다. As a result of the experiment, the bacteriophage PALS2 genome (genome) was found to have a nucleotide sequence of 268,748 bp in total length and 24.66% of G + C content (the nucleotide sequence described in SEQ ID NO: 1). Therefore, the bacteriophage PALS2 has a tail and is classified as a 'jumbo phage' having a genome size of 200 kbp or more (Yuan, Y. & Gao, M. 2017. Jumbo bacteriophages: an overview. Front. Microbiol. 8 , 403). As a result of ORF analysis, a total of 279 ORFs were predicted as shown in FIG. 2, and in general, small-sized bacteriophages directly possess several DNA and RNA polymerase-dependent genes that depend on the host bacteria.
한편, 본 발명자들은 상기와 같은 방법으로 얻어진 '점보박테리오파지 PALS2'를 미생물기탁기관인 농촌진흥청 국립농업과학원 농업유전자정보센터(KACC)에 2019년 12월 20일자로 기탁하여 수탁번호 KACC 97035P를 부여 받았다.On the other hand, the present inventors deposited the 'Jumbo bacteriophage PALS2' obtained in the same way as described above at the National Academy of Agricultural Genetic Information Center (KACC), Rural Development Administration, which is a microbial deposit institution as of December 20, 2019 and was given an accession number KACC 97035P.
[실험예 1: 본 발명의 점보박테리오파지 PALS2의 숙주별 감수성(susceptibility) 확인][Experimental Example 1: Confirmation of host-specific susceptibility of jumbo bacteriophage PALS2 of the present invention]
숙주별 감수성은 연속 희석 적하법(serial dilution dropping method)을 사용하여 확인하였다 (Adams, M.H.1959. Bacteriophage, pp27-34. Interscience Publishers Inc., New York). 12시간 배양한 세균 배양액과 0.3%의 소프트 아가 배지를 섞은 후, TSA 플레이트에 부어서 상온에서 15분간 건조하였고, 그 위에 희석배수 별로 희석된 점보박테리오파지 PALS2를 떨어뜨리고, 상온에서 말린 후 30℃에서 10시간 정치 배양하였다. 균주가 파지에 대해 감수성을 갖는 경우 플레이트 상에 용균반이 보이게 되며, 이는 세균 세포가 완전하게 용해되어 사멸된 결과를 나타낸다. 만약 감수성이 약한 경우, 뿌옇게 영역이 생길 수 있고, 리소스타핀(lysostaphin)과 같은 세균의 증식을 억제할 수 있는 항균성 효소가 존재하는 경우 억제 영역이 생길 수 있다. 하기 표 1에서는 박테리오파지 PALS2를 사용하여 메티실린 항생제에 감수성이 있는 황색포도상구균 세균(MSSA)과 메티실린 항생제에 저항성을 갖는 황색포도상구균 세균(MRSA), 대표적인 그람양성균 몇 종을 대상으로 숙주 감수성을 실험한 결과를 나타내었다.Host-specific susceptibility was confirmed using a serial dilution dropping method (Adams, M.H. 1959. Bacteriophage, pp27-34. Interscience Publishers Inc., New York). After mixing the bacterial culture medium cultured for 12 hours and 0.3% soft agar medium, pour it on a TSA plate and dry it at room temperature for 15 minutes, drop the jumbobacteriophage PALS2 diluted by the dilution factor on it, and then dry it at room temperature and then 10 at 30°C. Time was incubated. When the strain is sensitive to the phage, a plaque is seen on the plate, which indicates that the bacterial cells are completely lysed and killed. If the sensitivity is weak, a cloudy region may occur, and an inhibitory region may occur if an antibacterial enzyme capable of inhibiting the growth of bacteria such as lysostaphin is present. In Table 1 below, using the bacteriophage PALS2, Staphylococcus aureus (MSSA), which is sensitive to methicillin antibiotics, and Staphylococcus aureus (MRSA), which are resistant to methicillin antibiotics, host susceptibility to a few representative Gram-positive bacteria. The experimental results are shown.
MSSA
MSSA
a) 'C'는 투명한 용균반(Clear plaque)을 형성하였다는 의미이고, 'I'는 억제 영역(Inhibition zone)을 형성하는 것을 의미한다. 억제영역은 박테리오파지에 의한 독립된 하나의 용균반이 형성되지는 않지만 어떠한 물질에 의해 세균의 증식이 억제됨을 의미한다. 'T'는 혼탁한 용균반(Turbid plaque)을 형성하는 것을 의미한다. 혼탁한 용균반은 온화 박테리오파지가 지시균의 일부를 용원화하기 때문에, 용균반 내에 용균들이 콜로니가 형성되어 불투명하게 보이는 것을 의미한다.a) 'C' means formation of a clear plaque, and 'I' means formation of an inhibition zone. The suppression region means that an independent lysing plaque is not formed by the bacteriophage, but the proliferation of bacteria is inhibited by any material. 'T' means to form a turbid plaque (Turbid plaque). A cloudy plaque means that because the mild bacteriophage lysate some of the indicator bacteria, colonies are formed in the plaque and appear opaque.
실험결과, 본 발명의 점보박테리오파지 PALS2는 메티실린 항생제에 감수성이 있는 황색포도상구균 세균(MSSA) 9종과 메티실린에 저항성을 갖는 황색포도상구균 세균(MRSA)을 용해시키는 세균 사멸능이 확인되었다. 그 외 포도상구균 3종에 대해서도 사멸능이 확인되었고, 포도상구균이 아닌 다른 속의 그람양성균에는 용균활성이 없었다.As a result of the experiment, the jumbo bacteriophage PALS2 of the present invention was confirmed to have bacterial killing ability to dissolve 9 types of Staphylococcus aureus bacteria (MSSA) sensitive to methicillin and Staphylococcus aureus bacteria (MRSA) resistant to methicillin. The killing ability was also confirmed for 3 other Staphylococcus aureus, and there was no lytic activity against Gram-positive bacteria of other genera other than Staphylococcus aureus.
[실험예 2: 본 발명의 점보박테리오파지 PALS2의 용균 활성능 확인][Experimental Example 2: Confirmation of lytic activity of jumbo bacteriophage PALS2 of the present invention]
황색포도상구균 균주에 대한 점보박테리오파지 PALS2의 용균활성능을 확인하고자 하였다. 점보박테리오파지 PALS2의 용균활성 확인을 위해 세 개의 시험군으로 나누어 실험을 실시하였다. 대조군(●)에는 숙주 균주인 황색포도상구균(S. aureus human isolate 93)을 액체배지에서 배양하며 실험하였고, 실험군(■, ▲)에는 숙주 균주인 황색포도상구균(S. aureus human isolate 93)을 액체배지에서 1시간 40분 배양 후, 점보박테리오파지 PALS2를 균 수에 대해 각각 1, 0.1 비율이 되게 감염시켰다. 감염 직후부터 시작하여 일정 시간 간격으로 대조군과 실험군 각각의 흡광도(OD600)를 측정하며 세포의 생장 및 사멸 정도를 파악하였다. To confirm the lytic activity of the jumbo bacteriophage PALS2 against Staphylococcus aureus strains. In order to confirm the lytic activity of the jumbo bacteriophage PALS2, the experiment was conducted by dividing it into three test groups. In the control group (●), the host strain S. aureus human isolate 93 was cultured in a liquid medium, and in the experimental group (■, ▲), the host strain S. aureus human isolate 93 was used. After culturing for 1 hour and 40 minutes in a liquid medium, the jumbo bacteriophage PALS2 was infected at a ratio of 1 and 0.1, respectively, with respect to the number of bacteria. Starting immediately after infection, the absorbance (OD 600 ) of each control and experimental group was measured at regular time intervals to determine the degree of cell growth and death.
도 3은 점보박테리오파지 PALS2의 용균활성능을 보여주는 그래프이며, 'ctrl'은 점보박테리오파지 PALS2 무처리군(대조군)이고, 'MOI(Multiplicity of infection) 1'은 점보박테리오파지 PALS2를 균수에 대해 1 비율이 되게 처리한 실험군, 'MOI 0.1'은 점보박테리오파지 PALS2를 균수에 대해 0.1 비율이 되게 처리한 실험군이다. 실험 결과, 도 3과 같이 본 발명의 박테리오파지 PALS2는 숙주에 감염 후 1시간30분(MOI 1) 혹은 2시간(MOI 0.1) 이후부터 용균활성을 빠르게 보이기 시작하며 그 용균활성이 20시간 이상 오래 유지되는 것을 확인할 수 있었다. 3 is a graph showing the lytic activity of jumbo bacteriophage PALS2, 'ctrl' is a jumbo bacteriophage PALS2 untreated group (control group), and 'MOI (Multiplicity of infection) 1' is 1 ratio of jumbo bacteriophage PALS2 to the number of bacteria The experimental group treated so as to be 'MOI 0.1' is the experimental group treated with the jumbo bacteriophage PALS2 in a ratio of 0.1 to the number of bacteria. As a result of the experiment, as shown in FIG. 3, the bacteriophage PALS2 of the present invention rapidly started to show lytic activity after 1 hour and 30 minutes (MOI 1) or 2 hours (MOI 0.1) after infection with the host, and the lytic activity was maintained for more than 20 hours was able to confirm that
이와 같은 특징으로 말미암아, 본 발명의 점보박테리오파지 PALS2는 MOI 0.1에서도 MOI 1에서만큼이나 오랜 시간 용균 활성을 유지할 수 있는, 효과적인 생물학적 조절제로 활용될 수 있을 것으로 판단할 수 있었다. Due to these characteristics, it could be determined that the jumbo bacteriophage PALS2 of the present invention could be utilized as an effective biological modulator that can maintain lytic activity for a long time at MOI 0.1 as well as at
[실시예 2: 본 발명의 점보박테리오파지 유래 엔도라이신 LysPALS21 및 LysPALS22의 확인 및 분리][Example 2: Identification and isolation of jumbobacteriophage-derived endolysin LysPALS21 and LysPALS22 of the present invention]
(1) LysPALS21과 LysPALS22의 확인(1) Identification of LysPALS21 and LysPALS22
BLASTP와 InterProScan 프로그램을 이용하여 용균에 관여하는 단백질의 도메인을 분석한 결과(도 4), N-말단 (N-terminal)에 용균활성(lytic activity)이 있는 CHAP(Cysteine, histidine-dependent amidohydrolase/peptidase) 도메인, C-말단 (C-terminal)에 세포벽부착(cell wall binding) 활성이 있는 SH3_5 도메인을 가지는 것으로 예측되었다. CHAP은 박테리오파지 엔도라이신(endolysin)이 가지는 전형적인 도메인으로, 이에 따라 해당 유전자에서 발현되는 단백질을 엔도라이신으로 확정하고, ‘LysPALS21’이라 명명하였다. As a result of analyzing the domain of the protein involved in lysis using BLASTP and InterProScan program (FIG. 4), CHAP (Cysteine, histidine-dependent amidohydrolase/peptidase) with lytic activity in the N-terminal (N-terminal) ) domain, it was predicted to have a SH3_5 domain with cell wall binding activity at the C-terminal. CHAP is a typical domain of bacteriophage endolysin (endolysin). Accordingly, the protein expressed in the gene was confirmed as endolysin and named 'LysPALS21'.
마찬가지로, N-terminal에 용균활성이 있는 아미다제 2(Amidase 2) 도메인, C-terminal에 세포벽부착활성이 있는 SH3_5 도메인을 가지는 것으로 예측된 용균단백질 또한 박테리오파지 엔도라이신이 가지는 전형적인 도메인으로서, 이를 엔도라이신으로 확정하고, 'LysPALS22'라 명명하였다. Likewise, the lytic protein predicted to have an amidase 2 (Amidase 2) domain with lytic activity in the N-terminal and a SH3_5 domain having cell wall adhesion activity in the C-terminal is also a typical domain of bacteriophage endolysin, which is a typical domain of endolysin. was confirmed and named 'LysPALS22'.
(2) LysPALS21과 LysPALS22 분리 및 발현·정제(2) LysPALS21 and LysPALS22 isolation, expression and purification
크기가 798 bp 인 엔도라이신 LysPALS21 유전자는 두가지 프라이머인 LysPALS21_F (5’- GCGGTCGACATGAAAACTAAAACTCAAGCT -3’) 과 LysPALS21_R (5’- GCGCTCGAGACTAAATGTTCCCCATGC -3') 를 이용하여 PCR 되었고 pET-29b 벡터에 클로닝되었다. 그 후 E. coli BL21에 형질전환 되었다. 이어, 재조합된 LysPALS21은 0.5mM IPTG의 첨가에 의해 발현이 유도되었다. 그 후 초음파처리를 통해 균주의 세포벽을 제거하고 원심분리를 한 뒤 상등액을 Ni-NTA Superflow column에 통과시킴으로써 순수한 LysPALS21을 얻을 수 있었다. 도 5와 같이 크기는 약 34.6 kDa 정도 되었으며 순수하게 분리되었음을 알 수 있었다. The 798 bp endolysin LysPALS21 gene was PCR cloned into pET-29b vector using two primers, LysPALS21_F (5'-GCG GTCGAC ATGAAAACTAAAACTCAAGCT -3') and LysPALS21_R (5'-GCG CTCGAG ACTAAATGTTCCCCATGC -3'). . Then, it was transformed into E. coli BL21. Then, expression of the recombinant LysPALS21 was induced by the addition of 0.5 mM IPTG. After that, the cell wall of the strain was removed through sonication, centrifuged, and the supernatant was passed through a Ni-NTA Superflow column to obtain pure LysPALS21. As shown in FIG. 5, the size was about 34.6 kDa, and it could be seen that it was purely separated.
크기가 951 bp 인 엔도라이신 LysPALS22 유전자는 LysPALS22_F (5’- GCGGGATCCATGGCTAAAAAACATATCGGT -3’) 과 LysPALS22_R (5'- GCGGTCGACTTAGCTAAATGTTCCCCATGC -3') 가 PCR 프라이머로 사용되었다. pET-28a 벡터에 클로닝되었고, 이후 형질전환, IPTG 단백질 발현 및 정제 조건은 상기의 LysPALS21의 방법과 동일하게 진행되었다. 도 5와 같이 크기는 약 38.5 kDa 정도 되며, 순수하게 분리되었음을 알 수 있었다. LysPALS22_F (5'-GCG GGATCC ATGGCTAAAAAACATATCGGT -3') and LysPALS22_R (5'-GCG GTCGAC TTAGCTAAATGTTCCCCATGC -3') were used as PCR primers for the 951 bp endolysin LysPALS22 gene. It was cloned into the pET-28a vector, and then transformation, IPTG protein expression and purification conditions were carried out in the same manner as in LysPALS21 above. As shown in FIG. 5, the size is about 38.5 kDa, and it can be seen that it is purely separated.
[실험예 3: 본 발명의 점보박테리오파지 유래 엔도라이신 LysPALS21 및 LysPALS22의 특성 분석][Experimental Example 3: Characterization of jumbobacteriophage-derived endolysins LysPALS21 and LysPALS22 of the present invention]
*(1) 엔도라이신 LysPALS21과 LysPALS22의 숙주 용해능 * (1) Host lytic capacity of endolysins LysPALS21 and LysPALS22
정체기 단계의 황색포도상구균 RN4220 배양액에 분리된 엔도라이신 LysPALS21을 서로 다른 농도로 처리하였는데, 그 결과 오로지 버퍼(50 mM Tris-Cl, pH 8.0)만 첨가한 control에 비해 효과적으로 흡광도가 감소하였다. 한편, 서로 다른 농도를 첨가하였을 때 농도가 높아질수록 그 흡광도가 점점 더 많이 줄어들었다 (도 6). 따라서 엔도라이신 LysPALS21은 감수성 균주의 성장을 단순히 억제시키는 것이 아니라 해당 균주를 용균시키는 것을 알 수 있었으며, 적은 양의 엔도라이신으로 감수성 균주를 효과적으로 제어한다고 판단할 수 있었다. The endolysin LysPALS21 isolated from the Staphylococcus aureus RN4220 culture medium in the stationary phase was treated with different concentrations. As a result, the absorbance was effectively reduced compared to the control in which only a buffer (50 mM Tris-Cl, pH 8.0) was added. On the other hand, when different concentrations were added, the absorbance decreased more and more as the concentration increased ( FIG. 6 ). Therefore, it was found that endolysin LysPALS21 did not simply inhibit the growth of the susceptible strain, but lysed the strain, and it could be determined that a small amount of endolysin effectively controls the susceptible strain.
엔도라이신 LysPALS22의 경우 50 mM sodium phosphate, pH 8.0 버퍼에서 최적의 활성을 보였다. 마찬가지로 버퍼만 첨가한 control에 비해 흡광도가 감소하였다 (도 7). 또한, 엔도라이신 LysPALS21 단독으로 사용할 때보다 LysPALS22를 LysPALS21과 함께 사용하였을 때 흡광도가 더 크게 감소하는 것으로 보아 특정버퍼조건에서 엔도라이신 LysPALS22는 엔도라이신 LysPALS21의 활성을 보조한다는 것을 확인할 수 있었다.In the case of endolysin LysPALS22, the optimal activity was shown in 50 mM sodium phosphate, pH 8.0 buffer. Similarly, the absorbance was decreased compared to the control to which only the buffer was added (FIG. 7). In addition, it was confirmed that the absorbance was significantly decreased when LysPALS22 was used together with LysPALS21 than when endolysin LysPALS21 was used alone.
(2) 엔도라이신 LysPALS21이 효과적인 항균 활성을 나타내는 조건(2) Conditions in which endolysin LysPALS21 exhibits effective antibacterial activity
정제된 단백질 LysPALS21의 특성분석을 진행하여 황색포도상구균에 대한 최대 항균효과를 갖는 최적의 pH와 NaCl 농도 조건을 확인하였다. 최적의 pH 조건을 확인하기 위해 pH 5.5부터 pH 10 각각에 대해 이에 완충효과를 보이는 버퍼를 설정하여 사용하였다: pH 5.5 - 50 mM Sodium acetate buffer, pH 6.5~8 - 50 mM Tris-Cl, pH 9 - 50 mM Glycine, pH 10 - 50 mM Sodium carbonate-bicarbonate buffer. 최적의 NaCl 농도를 확인하기 위해 50 mM Tris-Cl (pH 8.0)에 NaCl의 최종 농도 0, 25, 50, 100, 150, 200 mM 로 이루어진 용액을 반응 버퍼 (reaction buffer)로 사용하였다. 한편, 엔도라이신 LysPALS21의 내열성을 알아보기 위해 4℃, 25℃, 37℃, 45℃, 55℃, 65℃ 각각의 온도에서 단백질을 30분간 보관한 뒤, 50 mM Tris-Cl (pH 8.0)에서 이의 효소활성을 측정하였다. 또한, LysPALS21이 효소활성을 나타내는데 필요한 이온이 무엇인지 확인하기 위해 단백질에 5mM EDTA를 쳐 단백질활성에 필요한 2가 양이온들을 제거한 후, EDTA가 없는 50 mM Tris-Cl (pH 8.0) 버퍼로 바꾸어주고 이에 Ca2+, Mg2+, Mn2+, Cu2+, Zn2+ 를 각각 1.0 mM이 되게 넣어주어 단백질의 활성 회복정도를 확인하였다. 모든 특성분석은 황색포도상구균 RN4220을 대상으로 진행되었고, LysPALS21의 최종농도가 300 nM이 되게 처리하였다.Characterization of the purified protein LysPALS21 was carried out to confirm the optimum pH and NaCl concentration conditions having the maximum antibacterial effect against Staphylococcus aureus. To confirm the optimal pH conditions, buffers showing a buffering effect were set for each of pH 5.5 to
실험결과, 엔도라이신 LysPALS21은 pH 8.0에서 9.0까지 염기 범위에서 95% 이상 항균활성이 나타났으며(도 8. A), 200 mM까지의 NaCl 농도에 대해 항균활성이 50% 이상 안정적으로 보였으나, NaCl이 없는 조건에서 최대의 활성을 나타냈다(도 8.B). 또한, 4℃에서 37℃까지의 보관온도에서 90% 이상의 활성을 보였고, 45℃부터는 활성이 40% 미만으로 감소하였으며(도 8.C), 단백질이 활성을 보이는데 Ca2+, Mg2+, Mn2+ 이 주요 이온으로 작용함을 확인할 수 있었다(도 8.D).As a result of the experiment, endolysin LysPALS21 showed more than 95% antibacterial activity in the base range from pH 8.0 to 9.0 (Fig. The maximum activity was shown in the absence of NaCl (Fig. 8.B). In addition, at a storage temperature of 4°C to 37°C, the activity was more than 90%, and from 45°C, the activity decreased to less than 40% (FIG. 8.C), and the protein showed activity Ca 2+ , Mg 2+ , It was confirmed that Mn 2+ acts as a main ion (FIG. 8.D).
(3) 엔도라이신의 항균 활성 범위(3) Antibacterial activity range of endolysin
다양한 세균에 대한 엔도라이신 LysPALS21의 감수성을 확인하였다. 하기 표 3에 나타난 것과 같이, 엔도라이신 LysPALS21은 메티실린 저항성 황색포도상구균 균주를 포함한 다양한 포도상구균에 대하여 강한 활성을 보였다. 현재까지 보고된 황색포도상구균 엔도라이신들과 다르게, LysPALS21은 그람양성균 중 엔테로코쿠스 페칼리스(Enterococcus faecalis)에 대해서도 용균효과를 보이는 것을 확인하였다.The sensitivity of endolysin LysPALS21 to various bacteria was confirmed. As shown in Table 3 below, endolysin LysPALS21 showed strong activity against various Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus strains. Unlike Staphylococcus aureus endolysins reported so far, LysPALS21 was confirmed to have a lytic effect against Enterococcus faecalis among Gram-positive bacteria.
MSSA
MSSA
한편, 도 9와 같이 이전에 특허등록된 황색포도상구균 엔도라이신들(LysSA11, LysCSA13)과 본 발명의 엔도라이신 LysPALS21의 엔테로코쿠스 페칼리스에 대한 용균활성을 비교한 결과, 본 발명의 엔도라이신 LysPALS21은 기존 황색포도상구균 엔도라이신들에 비해 엔테로코쿠스 페칼리스에 대해 뛰어난 용균활성을 나타내는 것을 확인할 수 있었다. 따라서, 본 발명의 엔도라이신 LysPALS21은 넓은 범위의 포도상구균은 물론 엔테로코쿠스 페칼리스에 대해서도 항균활성을 가지는 것으로 볼 수 있다. On the other hand, as a result of comparing the lytic activity against Enterococcus faecalis of Staphylococcus aureus endolysins (LysSA11, LysCSA13) and endolysin LysPALS21 of the present invention previously registered as shown in FIG. 9, endolysin LysPALS21 of the present invention was confirmed to exhibit excellent lytic activity against Enterococcus faecalis compared to the existing Staphylococcus aureus endolysins. Therefore, it can be seen that the endolysin LysPALS21 of the present invention has antibacterial activity against Enterococcus faecalis as well as a wide range of Staphylococcus aureus.
[실험예 4: 본 발명의 점보박테리오파지 유래 엔도라이신 LysPALS21의 혈액에서의 황색포도상구균 항균효과 확인][Experimental Example 4: Confirmation of Staphylococcus aureus antibacterial effect in blood of jumbobacteriophage-derived endolysin LysPALS21 of the present invention]
황색포도상구균 RN4220을 대상으로 하여 본 발명의 엔도라이신 LysPALS21이 혈액환경에서 균을 제거하는 활성을 가지고 있는지 조사하였다. It was investigated whether the endolysin LysPALS21 of the present invention had the activity of removing bacteria from the blood environment by targeting Staphylococcus aureus RN4220.
먼저 황색포도상구균을 TSB 배지에서 한밤 배양하였다. 이 황색포도상구균의 배양액을 TSB 배지 부피의 1/100 만큼 접종하여 2시간 진탕배양 후, 이를 Phosphate-Buffered Saline (PBS) 완충용액으로 세척 및 106 CFU/ml 이 되도록 희석해주었다. 이후, 준비한 말의 혈액에 상기의 균 배양액을 최종농도 105 CFU/ml이 되게 섞어주고, 이를 24 웰 플레이트에 1 ml씩 분주하였다. 단백질을 목적하는 농도(0.3 uM, 1.0 uM, 3.0 uM)에 맞게 준비하여 이를 각 웰에 넣어 25℃에서 정치배양하고, 1시간마다 샘플을 샘플링하여 희석 후 TSA 배지에 다팅하였다. 샘플이 마른 후, 플레이트를 37℃에서 한밤 배양하여, 콜로니 수를 통해 엔도라이신의 혈액내 효과를 확인하였다. First, Staphylococcus aureus was cultured overnight in TSB medium. This Staphylococcus aureus culture solution was inoculated as much as 1/100 of the volume of the TSB medium and cultured with shaking for 2 hours, washed with Phosphate-Buffered Saline (PBS) buffer and diluted to 10 6 CFU/ml. Thereafter, the prepared horse blood was mixed with the bacterial culture medium to a final concentration of 10 5 CFU/ml, and 1 ml was dispensed into a 24-well plate. Proteins were prepared at a desired concentration (0.3 uM, 1.0 uM, 3.0 uM), put into each well, and incubated at 25° C., samples were sampled every hour, diluted and then darted in TSA medium. After the sample was dried, the plate was incubated overnight at 37°C, and the effect of endolysin in the blood was confirmed through the number of colonies.
그 결과, 엔도라이신 LysPALS21(도 10의 A)과 논문연구되어 현재 임상2상 진행중인 엔도라이신 SAL200(도 10의 B)을 혈액에 다양한 농도로 접종한 결과, LysPALS21이 SAL200만큼 혈액 내에서 효과적으로 균을 제거함을 보여 준다. 따라서, 엔도라이신 LysPALS21 또한 황색포도상구균 제어 면에서 사업성이 있다고 볼 수 있다. As a result, as a result of inoculating the blood with endolysin LysPALS21 (FIG. 10A) and endolysin SAL200 (FIG. 10B), which has been researched and currently undergoing
기탁기관명 : 농업생명공학연구원Name of deposit institution: Agricultural Biotechnology Research Institute
수탁번호 : KACC97035PAccession number: KACC97035P
수탁일자 : 20191220Deposit date: 20191220
SEQUENCE LISTING <110> Seoul National University R&DB Foundation <120> Jumbo bacteriophage PALS2 and its endolysins LysPALS21 and LysPALS22 from Staphylococcus aureus <130> YP-20-055 <160> 5 <170> PatentIn version 3.2 <210> 1 <211> 268748 <212> DNA <213> Bacteriophage PALS2 <400> 1 atggctataa cacagtattt ctctaacgaa caagagaaaa tagatttcct taataatgct 60 aaaatagata ctgaaagcgt tattaagata ggaagtactt catacgatgt caaagataaa 120 tggttcaata tggcaactaa gttctttgaa attgatacag aaaatactcc tatagatgaa 180 aatgaagatg aagatttaat ttcattatta aaagctggat tatttggtta tattaatgaa 240 attaattcac atgaagttaa aaacgctata tatcacagaa atgtattata cgatgaatta 300 ttcttaaata cagcttctat tcctatgtct atatacaatt ttgctaagtt gtataatgta 360 cctattcaaa tggctaaacc tgctaatttt aaagtagatt ttgttattag aaaagatgat 420 gtattaaaat taccttctaa agaaattgta tctactcaag aaatagataa aaagaaatca 480 ttaaaaactt atgagataaa attatctaaa gaccaagatt ttacaatagg tagttttaaa 540 tattgtttac cgtatgatgt atcaatggta ttaaaacaat atccaataac tagagatgga 600 aaagatgcaa tagattataa aattacagct agatatgata tagataacga tctatttaaa 660 ttttcttcta ttttagataa taatgtcaaa gtaactaaga atataataaa tggtgtagat 720 tatatgtatt tctctttaga tctatatcaa atagaaagag tttctaaaga atttaatata 780 actagcaatg atatcgctga aaatatttat ttcaatgttg gttatgaaaa tcaattgtct 840 ggttttaatg tattctatga atacttaggt acaagaacac ctatggaaac ttattttaat 900 aatactttta ctccagatac agataatcct ttctgttatt ataatttcaa agatgataat 960 tcattagaaa tttcattctc aaacatggct aattctttta gacctaaagc taatagcaaa 1020 gttattgtag aaactttaac tactaaaggt gagaaaggca actttagtta taatgataat 1080 ttaaatgtag cgttagattc taataacaca tttgaaaaag taccaataac tattcttcct 1140 aaaggtaatt cagttgatgg tcagaataga ccggatgttt atactgaaaa aagaagaata 1200 attaataaag ctattactag agataatatt attactgact ttgatattaa aaactatttt 1260 aatgatgtta atgacaataa taatattaat aattctttta ttaacttcat taaaaaacgt 1320 aatgatcttt atacacgtat gtataatgct ttcttattat taagagatag tgatagtaag 1380 gtaatgccta caaatactgc tccttatata gaacttccta aacagtattt tgagggaaat 1440 acttcattag gtaatgaaga agatggttat gtaatacctg agaacagttt attcaaatat 1500 gatcaagata gtaaaaaata cgttcacatt gaaaaaggtt tagatgatgc tgatgagaaa 1560 gaaaaatttg aaaaagataa agattcttta tattatgtaa atccttattt aattaaaatt 1620 aataaatatc ctttcttatc tactaactat tataaacttc atgtaaatga actatttact 1680 actgaatata aatacattaa tgaattaata cctaataaca ttacaactac cgatttatat 1740 gtagaaaaat taaatgactt caaaaatact ttggaatcag atacatttaa atttagttta 1800 gaaattggta tggacagttc acttcaagaa atgaaagact tattaaaagt cagagctgta 1860 ttattatctc aagaaactgg tgaaagatac ggttactttg agttgaatcc agaagaaagt 1920 attgagtctg aaaataatat tattgatgag tcagattcaa ctgtagataa atcttcttta 1980 tattcaggaa tgatatctac taatagatct ttccataatg gtaaattatc tataacggat 2040 tcactttata atgataaagg tatagtacaa gataatgtat ttatagatga aaaatttgta 2100 gtcaaagtag gattactata taaagatgaa gatatgagat atttcaatga tcttgatata 2160 tctgatgaaa tgaatttctt taaagatgaa ttccctagtc atagagatga tgaagttaga 2220 gattatacat tggcttgttc tatggaaact tttgaaggag tatctatata caaagacatg 2280 tcacacgtaa tgaatagtac agtatctatg actgatgaca gttgtaaagt agaattagtt 2340 cctttattct cattaggata ctttatgaat aattatgaag aagtttatag cgtattagaa 2400 ggatataaag aaatattaga agatgctata cctagattac aaaataacac tagtatagat 2460 atgaagcttt ataatactaa aggaccttct aataattatt atctagatac tgaattagac 2520 gatgataact taaataataa atatatctct agaacggata tattattaga tttaaatatc 2580 actctatatg cacctattaa tgatttctta gatggagaaa ttaaacgtta tatttctgat 2640 tttgtagaag catgtaatga aaaaggtgta ttacctatat ctaacttaat tagattatta 2700 gaacaaaatt tcgatataat caagtatata gtatttaatg gtatttctgg taaatatgct 2760 gaaaaagtag acaaccatta tcaaaaacta cttaatacta atataaacta tatggatcta 2820 agtaaacaag aaattattga atatgttcct gaatttatta atatcaaaaa atctcttaaa 2880 gataataagg ttgaagtgag taatgaagat tcagaggatg gaacaacggt tattgattta 2940 ggtttatctt acgatgatgt agttaatata acttattcaa tctcataaaa ataaaattat 3000 aatataaaga aagaggtata aatataatgg ctaaaacatt tatttctgat taccgcaaaa 3060 aacaagctgg tttaaataga aaagcagcta atgctttaga acagaaaaaa tacactgatc 3120 aaattaatga agaattagaa gtttcaaaag agaaagattt aattgcaggt agaaataata 3180 aattacgtgc aactaacaag aaagctattg ataatgctaa aaataaatca gaaagagaat 3240 taaaagattt aaatgcacaa actatcatga ctactttatt ctcagcatta gtatttaata 3300 ctttccctaa caaaattgct gacaaatcta aattacgtga gaaaattgtt tctaagagta 3360 gaatgttctt taacgaagca attaatgcag aattagctga ctatcaaggt agtgaagtat 3420 tctctaacgc taaatttaat gcagacgtat acactaaaga tgctcgtgga gttattgatc 3480 ctaaagactc tattaaagga gctaaagtag tatacaaaaa aggtagaact gaattcgatt 3540 acctaacaaa tgtagttgct aagaaaattg aatcagctgt aattcgtgaa tctgaattag 3600 ttgatgttcg tgaaaaatta aacgaaagct tagcagacac acataaaaag aataataaaa 3660 cactattccg tactttacat gaatcggcta tcaataatat tgtaaatgat gaagcttacc 3720 ttaatgaaga agtttcagca gaagaagtta acatggatgc tttagtagaa gctactttag 3780 attatactat tatggaatta atccatacag ctaaattgag cacattcaat atgagtgaag 3840 ttcaaaaagc tgttaagaat ggtacaatta aagttaatac taaacaaaat agtaaaataa 3900 aacctgaaaa tggttctact aaaccttcag ctgatggagt taaacctaga actattgaaa 3960 atgaaaataa accaaaatca ggttctgtta aattaaacga agaataaaaa aaaaataata 4020 taatccccct aatactaaat taatagtatt aggggaatat ttttaaaagt catcaaatat 4080 ttgacctggt tcaaatgttt tatcttcttg tgaaggtgat tgagctaatg cacttgattt 4140 aaattgatta gctatagttg acattttatt tttagcacgt tcagaatcca tagtattttc 4200 taaattagaa ccaattgatt ctacaccttt aatttcaggt gttccttcat caacagcaag 4260 tttaaatgaa ttgtcaaatg gttgagcaaa gtattcaatt ctatcttcac ccattttacc 4320 acgactagca attagtttaa atgataaatg atcgtcttga gattcatctc tagcattttc 4380 tctatttata atcataccat agtctaagtt ttctaatatc attgctgatt ctgcaatttg 4440 acttctatct aattgcttag caatatctgt tttattttca gataaagctt tttctacatt 4500 tctatatgct tctctgttta attgtgctgc tgttactaac ggtatttctt tctctttagc 4560 aaatactgta aattcgttag tgatttcacc aagtctaata cgtaaatctt caatatgatc 4620 tgaagctcta atacgtttta aatagtcttg taccatcata atcatttgat atccttgatc 4680 tgctaaattc tcatatactt catacaagta gtcagttgat acttcattat ttttcttata 4740 ttcaacaact aaactaattc ctgttttctc ataagtatat ttaattaatt catttacaca 4800 ttcttgaggt gtttgatctg actcactcat agaatatcca gtaatatatt catacatacg 4860 atctaatgat tcactcatag agttttccat agttaaataa taaactactg gttttttatt 4920 aggatctaat gattgtatgt cacttgcttt attagctagt gtaactgaca ttaacatatt 4980 taataatgta cctgatttaa atgattttgg tgtcccgaag aatgaataaa cacgaccatt 5040 ctcgaaacct ccattaatca ttttattcaa catcttataa ccagttttta atttattaga 5100 tggattacgt aatttttcaa tagaatctgc cattacttct acagcattat ctacttctaa 5160 aaagttaata aagctatttt tagcacttcc cgctccatta gaagttcttt taataacttt 5220 agtaacatct gatattggtt ctaaaacttg tttaagtaaa tcagttggat ttaatctatc 5280 catagtaatt tgatcataaa tatatttaaa tacatctgct ttttgataaa gttctaaagt 5340 agcaaatctt tctttaatat aagtattaat ttgatcaatt tctctatctg acaattgttc 5400 tatttcattt ttataatagt tatcaattgt tttaagagtt tcatataaat gactttctga 5460 catttgattt ttaaatttat cgattaaatg ttcaattaat atttctggtg attcaataga 5520 ttcttcaatt cttattttaa ctaattcttt aagaacttta attgtatctt tttgatgttg 5580 ctgcccttca tcatatacat actcttcatt aatgttctct aaaaatttat ttaacctttt 5640 taaattagtt gcattaatta atctattttc tgtaatagta tatttaacaa tttgtattaa 5700 tgtattataa ggtatactta tattagcgta atttataagt tgattatttt cattaatgta 5760 aaaactttcg ttgttttttc cttttgaatt gtctaaaaat gccataatgt caaacactct 5820 ccgttactat tatttttctt ttgttaagtt gatcaagtct tcaaaatctg gattaataat 5880 atttttaact tctttcaaat ctaattcttt atcatgtttt atagaattaa atttaacaat 5940 tgtttcaggt gtatcaagtt catcatctaa tatgaattga tacttttcat ctacttttac 6000 ttccttgata tttttgttgt taaattgaac tttgatattt ttatcagaac ttgaaatttg 6060 cttaattata tcaacgtcat ccttagaact agaaacaaat cttacataat cattttcttg 6120 acgtaactca ttgattattt ctagtttctt ttggtctgtt agctcctcat attgatccat 6180 atttatagta acgtaagttg gtgcgtcttc attttcaatt aattctacat tgtaattgtc 6240 tgtatcaaga tcattagtta caactaaaaa tcctttatct tcagtatctt taaatgaata 6300 tcttgaatat gaaccagtgt aatatacttt atctttatat tcgtgataat catgaatatg 6360 accatataca gaaacgcctt tagtaactct cattaattct tttgcttcta atattggagc 6420 tgacttaaca ggattttctg aatcatcttc atccggtaca aatgtaacaa aatcaatcat 6480 tccatgacca aatatattat catacgtatt gtcctcaact gaatatagta actcattata 6540 aaattctttc ttgtcatctg gatattcttc aggtatatat aatacattaa cttctttacc 6600 attatgctta attaactctg attctaatga attaataatt ttaaaattat catactctaa 6660 ttcgttttgg ttaaatacat caagttgatt aaaatcatgt gttttagttc ctttaatcaa 6720 tctgagtaag aaatttttat ctttagataa ttcaaacatt gtatccatga attctagaac 6780 ttctttacca gcaggttcat taaatctaat aactctatca aataaatcac ctgaaataac 6840 taccatatca atatcatcat tatctttgat gtattttaaa aaatatttat ctaattcttc 6900 tgataatttc ttaggattct ttttaccata gtgtatatca gctattacaa ctgttttaaa 6960 ttcattactc atttttatca tcctttgcta aaaagtctat catcttcata agtgtttctt 7020 ttacatattc taaacttttg taagttgctc tatcgtcttt catcattaga ttgttgaaat 7080 atatttctgg agacaaatca tctattaagt gacaacaatc aaaaccaatt attccattat 7140 tatcatacgt aattccacca tgagaataat attcaacatc tttatcataa ttatctccaa 7200 cttcaatata gccatttaaa aatcctaaat catgtctgac tataaatgct ttataacctt 7260 tatattcaaa ttcatactta ttctttctaa ctccaagtat tttatcttct ttttctataa 7320 tatgtttaag tgtatcagca tcaatcattt tgtttattca tctccattat ctcgattatc 7380 tatttccatt aatagttgca tttttctatc aaattcacca gattcaatat tttctttaat 7440 agtttctttt aatttactgt caatattttc tctattagtt ttaatgaatt caaatactgc 7500 tttagctaat tcatcatcca tactaattaa attagcttca ttattttcat caaaatctaa 7560 gtaagcaaaa gctgtagttc caaaacatgg taatccacca aacatcatga aattaatatc 7620 ttctgttgta aatctgtctt ctacttttcc aaaataagta aatgaaacta ctgaatgcat 7680 tggtgctggc attacatcca ttgttatatt ctctactggt atatccaatt cttcagccat 7740 aacctcatac atattttctt cttcaaattg gattttcttt ctagtataat tatcctcatt 7800 aggtttaata aaaacaaaat taatttccac tatccatttc atctcctgta tattagtatt 7860 ttattatatt tatatattaa ttcacatttc aaaatttctt aaccaaaatt ttttaaaatt 7920 cacacataat aatataatat taggggttag gggttaagaa ttaaaaatat ataaatatta 7980 ataattactt taatataata tatatttaat atataaattc atttttaata aatatattta 8040 ttaaaaataa tattaataaa aaattaatta ataaatatta atgaaattta tacatgtata 8100 agaaaataat gaaaactaat aaaaaatgac tataacaatt aaatattaaa ataaaagaca 8160 gaaaaggtga aaatattgaa aacttatggt ttaaatgaat cagaattata tagacaatta 8220 aacttagatg taaatagatt tactaaacaa attaaatcag aacatttaat gggtcaagat 8280 caattagcag atacatttag tattattaaa aaccgtataa accaagcttc taaaaacgaa 8340 gtaatagata aattagagaa tggagatatt cttctactta attcaaaaga agttaaatta 8400 cctaacttta tgccagtatt aaacattcaa ggtaataaag ctttagtaaa tatcactcct 8460 tatatcaaat ctaatatgag tattaatcca aattcattat ttggtttagc tcaagcaggt 8520 ttaattaata ttaaagttaa gaaagatgct aataaaatta gaaacaacgc taaattatta 8580 atttattcta gtcagattta ttctaaatta actactaaag taatggacaa actttatgca 8640 actaatatta ataaaaaaga ttctgactta atttcataca tgtttgcaaa gttcttttta 8700 gttagtatta tcggtagaac taatgatgat tcaacggaac agattgcata taaatcatgt 8760 cacaatagaa cagattttga agttattaaa gatatggaaa ataaattcga tggtcaagca 8820 tcaatgttaa acctattcag tttatttaaa gaatttaaaa aacatcctaa ctttaataaa 8880 ttttcatcaa gatcattcat tgagaacttt actaaaatgt acggagaaac ttcaatatta 8940 gctattgatc atttaccttc attctttact atgatctttt cagcttatgt aaatgcagga 9000 attaataaag aatttatcat tcttaatgca attaatgata aaattattat caactgttat 9060 agaagtttct tttaattaat tagagtcaat caacttaatc aataacagtt gattgactca 9120 tatttatgaa agaaaggaga actgaagtaa tttgagtatt aaattaaata atgaactgta 9180 ttataatctc agagataaaa ctagactaag taaagtagaa aatactcaag aattagctac 9240 tggtagtttc tacacatttt ataatgattt acttttagag attagatacg ataataaaat 9300 atatgtatat acaggatatt caactcaagg agaacatgta ttagagttaa gttttcttaa 9360 agaagaatta gacaatgata ctatagaaga tgtatttatg tacgataaca tacttgtaat 9420 aattagtgaa aagggttatt acagatgttt tatggatcaa ttaacagaaa atgttaataa 9480 cacttcagct gaagttgttt acagttataa tttctataga tcaagtgaag aattaaatta 9540 tagaccttat tctttaatag atgatatgat ttgtattaaa gaagctaatg atactttagt 9600 aattagaagt attaaaacag atgcttacac taaaacaatt gtatttaata agaatattga 9660 aggttttagt ttcttatatg aaaatggttt agctatcagc ttttatggag aaccttatca 9720 tattcatgtg tatgacttta aagaagaaaa atacactcaa gattttacca ttaatgagaa 9780 tatcaatcaa tatgaatatg atatacaaca tcaaataact agaatattta aatttaaaaa 9840 ttctttatac tatgctactc gttcaggtag aatatataga agtgatatta aagataaatt 9900 aataagctca atgtcatata gattctatca atcaggttca tctattgatt atattaaatc 9960 ttatgataat tatatcactt tctctaatag aagtaataat atactaattt ataatactga 10020 ttatgataga aaagaaattc ttaaaaatga ttatttagtt aaatcattag ctataagtaa 10080 ttttattatg gtagtttctt tatatgatag tattgatgaa gattataaga aacgtattat 10140 agaaagtgga gttattcctg aagatgttaa tttaaaccca gttcataaat atgtaatgta 10200 taatccgcct agtatagaag ttttaaaaga gaaattagaa tatagatttg ataaacctga 10260 agatccattg gtatatatta accttaatat taaattagct gaaaataaat taaataattt 10320 cgatagaagt caatatcgtg ttaaatttaa tattagtcat tcagataact ctaatgtagt 10380 tgaagaatct gacgttaaaa tatataaaca gcaaggtaca gttaaaaata tgtacattaa 10440 aattggtaga aaatctcaat gggttgataa taataaatta ctctctttat tagaaaatgg 10500 agaattatta tacagattca ctatagataa tatagataac tatgtaactt tctataatat 10560 caattatcct aatataggaa gcgattttta tagacattta actgatactg aagtatttcc 10620 cgatagatct cctgagaaga gtcactatga tgctttatca gaagaattaa atattaaaga 10680 tatatttaaa ggcgctgaag atgaaaaagt tatttcatta ttatccaatt tagtaaatga 10740 gaaagttata tacccttcat ctaacttacg tattgattct gaagatatgt atttagatta 10800 tccagattat gatccaagaa gatatattga tttaagtaac gaatatccta atgggcaatt 10860 agataccaat gtaattaatt cagatgtata ttttgatggt cttaaaatat ttaaaaatga 10920 tattcttcag aaagacaatt ttgatggttc agttaacgtt tatttaaatc atttagctat 10980 gaaaaaatat atgaatgata agaattatga atatactatt catgatagaa aattatctaa 11040 acatgataat ttcattatat caaataaatc tagaagctta tatcaaacag aaaaattaat 11100 ggttaaacat acagttacta atgattatga aaaccaaaca tcattactac caactaaagg 11160 tattttatta cctaacacta gagttaatca atttaagatt caaaatatta gagtatacgt 11220 taaagtatac aatactaatg aaaatggtaa tgaatattat catagattaa atccaagaaa 11280 ctttaatctt tggattgata aagaatataa tatgcttaga gttgctgtat atggtataca 11340 aattccagaa ggttctacat taatgattat ggataacggt cttactaata atgtcatttt 11400 atatgataaa cttaattaca ttaagcgtga tattgatagt ttacctatag ttgaagttgg 11460 acctaatgga gaattattaa cggaattaaa tcgaagaact gaagatgttg aagttattgt 11520 agacggatta actttaatac ctggtaggga tttccatgta atgaacacac ctaatgatcc 11580 agatattcct tctttagttg ctttcagaaa tgttattcct aatacatcta aagtagaaat 11640 tacattatta aatgaaaatt catctgacgt atattacttt aaacgtcctg cagttgacac 11700 aactaatgta tttgtattac cagatgataa gagaatattt actaataata tatatcaaaa 11760 tgatccatat aaagatatta acttattaaa aaattctgat gaagatgtta taactaaaga 11820 aaatgtagtt aaagaatacg aattgcttga accattagag aaaaatgtag attatacatt 11880 aactatgaga ggtcaattac ctattgatat tgatcatctt aatataactt ctaatggaac 11940 tactaaatct attgccgaaa ttcaatcaaa ttcttatgat gaagatacta aaacttatca 12000 agttaaattt aaactagaag acttaggaga aggttataat actggtttag ttattagaaa 12060 aactcaagaa agtactagag atgttaaaat tgattggatt aaattgaaaa aagaatctca 12120 ttcaactaga ttatgggaat cattctctca aggtcctgaa tttaagaata aagctcttaa 12180 ctttgaggta tttgtcaata acaagaaaat tcctaataat tatgtaactg tattgaattc 12240 caaagctatt aagataagtg agatatctgg atatgcatta aataatgtaa tgattagatt 12300 taatttctct tatgatgaaa tgttacagag aatcatcgat aattataaat ataaaactat 12360 cgatgttaat gaagatagat atcatgatga tagtattgct gatattaaat ctccatttga 12420 tacattaact agtggaaaac aagctaaaac attaggtaat ttgctaatta tacaactaat 12480 caatagtggt aaaaatattc ttgattgtaa tgttgataat ctacctatag acgttaatct 12540 taatacagat attattgaaa atagttatat cagaaagaat attaatttag atatgaatag 12600 aactaatctt attaagacta ttaataaaat tagtgattat gtaaatgaaa ttcttgatgt 12660 caataaaaat aatgaaaatc tattattgaa tagtaataat cctagtttct atgtgatgaa 12720 taatagaaat ttattaaaat ctacagatga ttttaaaact aatgaattta ctgctgaatt 12780 atgggcatat agaggattta atgatgaaaa cctaaaaaac gtctttaaag atgggaaatc 12840 atatacaata ttttttgatt taacatcaat aaataaaaac actggaggag aagttaaata 12900 tcctcaatat ggtatagctt tatatgattt tgataaaaga gaaactattg ggagttcatt 12960 aataaataat atagattttc ctgaaaatga agaaaaaagt atgtctttat atgtaagtag 13020 agaaaagtat cctgataatc taggaatatt attttacact ggcgtaaatt ctactgatgg 13080 gaatgataga ataccacaag tttctagatt tagaaatatg agaatatttg aagtttatga 13140 tgacggatta tatacacctg cacctgaaga taaagttcat tctcaatatc cttattctaa 13200 aatcgatgat tacaatagat attttgaaaa taaagaaagt attaaagata ttcacattaa 13260 aaataatgat atttatttag attttaaagt agatgaatct ttattagaaa gaaataaaaa 13320 atatacattc tcattctatg ctagaaataa atctaaagaa gatgttagat ttattaatga 13380 agatttagat atgaatttct taattaaaaa agatgaattt aaagcttatg tagattatat 13440 ctttattgat gaggatatga atgtgaatga tctattatcc cgaagtaaat ttattcaaga 13500 atctgatgag aaagacattc atctagattt atttggattt aaacttgaaa agggattaaa 13560 taaaacagat tatcttccta atatcaatga tatagaaggt ggggatttac tttctaatat 13620 ctttaatata gatgaaaaag ataattcaaa cctattaagt ttgaatgaag atttcaaaat 13680 agacatgtat aataaagagg aagattatat agactttaac aatatcgata cttataatct 13740 agataatgat gaattctata cgctatcaat ggatgtaaaa gtagaagaaa taaatgatct 13800 aagtactaaa tcattatatt cgggttatat tgataaggat ggaaattata cttcagctaa 13860 aaacgtctat tatctaccat tagataaaaa taaaattaat aaaactttta gagcttattt 13920 catatattat ctaagagata ttaaaaatat taaatctttt gtagtcagat ccggttattc 13980 taaagagcaa tcttctaaaa atgatatgaa gttcagtaaa tttaaattag aaaaaggtaa 14040 aatagctact ccttattcta aagcagtaaa tactgtagaa aatattatta tagatccaga 14100 aatataatat aaattatccc aatacctttt taatatataa ttaggtattg ggattttatt 14160 aaaacatgca tttattatga aattagacga aaggagccac acttaatggt cctcatgtat 14220 ttaaacgaag aggaaaatat ttatattgaa gattacttat ataaacctat tgaaggtaaa 14280 catacattaa tagtgaaaaa tgatagaaat acgcctattg aagtaaccat taatagaaaa 14340 gttaattctt tagatattaa taaagtttat aatcatagag ttaataataa ttcttcatat 14400 gaatttgatt ttcctataga tgatactatt cctccggata tattatcttt atttatagat 14460 aaacaaaata tgacttatga aaatagtaat gatgttttaa atgtacctta tatagtccca 14520 gaaggaaatg acaatataaa cccagtagta tacaatatta gtgctaatga tagtttttct 14580 aatattagtt tagctgaaaa tatagaattt attcctgatt ctaatagtgt agacggtatt 14640 acagaaatat ggtataaatt tgataataat gaaaataatt tgccaaacta tagatcagga 14700 acactagaaa aagtaactaa agataaaata ggttctttat tatattctaa tgactttaaa 14760 tatagtgaat tatacttaca tttgttctct agagatggtt ctggcaatac ttctgaagaa 14820 aatataattc ctattgatat agaagttcct tcttttgtta ctgacggttt taaaattaac 14880 gatacagaat tatacgaagg aattgaatta gattctttca actcaaatac attatttgaa 14940 ttttctcaag ttaaaactac tagagatatt gatgtgtatt acgatataca attagtatca 15000 gttaataaag acactaaaga agaacaagtt ataggtaaag aatttaataa aacaccttat 15060 ccaggaacta ttgattttga atttacacct atcaatatag ataacgattt atatacgtat 15120 tatgtaaata taagaacttc taatgcttat ggaagaagtt taggttttgc taaatctcct 15180 aatttctcat ttaaagttaa agaagatttt aatgtagact atattgaagt ggatgaaagt 15240 cctattgtag cttttgatgc tgatggatct cctagtataa actctaaaga taagacttta 15300 gtaatagggt attctggatt caatactaga tctctatata gagagataga agttgaattt 15360 agacatagag atactagaga taaggatgtt cctgcttctc catggagaag tttaaaaaca 15420 gtgtatttag gtacagaaaa tggtgaaata caagttccat ttgatactgc tatattagat 15480 ccaaacggat ttaaaatata tgactttcaa gtatctaaaa aatattcaga agattcatat 15540 ataagaaaaa ctaaatacga tttaatggca gattcacatg tagtcaatga cgaacaaact 15600 tctaattact ttacagcgat taaaattcct acagaagtat taagaaatat gaatgttcaa 15660 gttcaagaac ttattcaagg agaaactttt acttcagaaa aaattagtat agataatgac 15720 ttaacagcac attctcgttc tagaacagat gcttacttta tagctttaaa cagatttgaa 15780 accaatataa atatgagtaa ttatgatgat atggattata tgcgtagtga gattagatct 15840 gttattaata ctaataactt taaacaagac gttaatataa ttcgtccata tgatgaaaca 15900 atggaatcat atgtagtttt tgaaagaggt aatgttgaat taaatagaga tttttgggat 15960 actaaaactt tatctaatac agattctcca tttataggcc aatataaaaa tattgaaact 16020 aatataacta catttattgg taacgaagct agtcaaaaag taattcttaa agatgattat 16080 cgtctataca gaaagaaaaa tcttccagtt ccagaagtaa ctactagtaa aactcctgaa 16140 atagttactg aagaagatgg ttcagaatca attatattca cttcagatgt ttcaatatct 16200 tctagtaata aatatggttt agaaactgtc attgattatg aatatgatga cgatgatcct 16260 gacacgccta cagatttatt tacaggatat actcaaggaa gtttattaga agatgcaggt 16320 ttctataatt tcacattaag aacatcacta acttatggtt tagaaacttt ctattcagaa 16380 cctagactat ataatttcca aattatatat gaaagtaata catttagaga acctgtattt 16440 agagagttag tgggtagtga tggtaagatt acattaacat tagaaactaa tactaatgat 16500 cctaaatatt cttataaatt tatagattct actaatgata aagatatcac atctacattt 16560 actaagtatg atacagatac tgaaaatatt aaatataaga gaaaaataga taattatggc 16620 atttattatt ttacagtaca atatactaat ggtatatttg aagatgaatt atctactgta 16680 gtaatctttg aaaaacctat taatccagat tctagtattt caggtatatt aaattaccat 16740 aaatcaacta atactaaatt atctaaccgt tataataatg cttatctaca aactaaagtt 16800 aatgatgtcg atgatagatt ttatgtagtt gatatagatg aatcaggagc taaaagtaaa 16860 ttaattgtat cttcaggata tactatacca ttttatgatc cagctacttt aaatatgatt 16920 gaagccactg taaaacaagc caatagagat catatacatg atccaaatag taaatactca 16980 tcaataaatc caacagatgt aaatggtgca ggtcataaga tttctagtaa agattcttct 17040 aaagtagaaa gagttgatgc tgatttaact ccagataaac ctattattag attattctca 17100 gaagatccaa ttgaaggaag tttcaatgaa tatcctaaag aaaatgatac taatatagta 17160 atgggtggcg ttgagatcaa tgttactaat ggagatgcta actgggaaac agaaataatg 17220 attaatggag aaaaatttaa agatactaat actgtgtatg aagtttcagg taatcataaa 17280 attgtagcta tatttagaga tagatttaac tatacaatga attacgctac agctaatata 17340 aatattaaga aagattattt atactctcct attaatatgg atctttattc tatgaaagaa 17400 aaatatgatg tcgataagtt taatttatta ccatttggtg aagagtttac agatgaagat 17460 ctaaataaat ttgatccgac taccggatta agtggtttta caaaactttc tagtggtgaa 17520 tttggtagta tactaatggg aactgtaaca ggacaaagtt acactttatt aactttaaaa 17580 ctaagtgaat gtcctaaatt aaaaccagat accgattata tttattcagt aactatagct 17640 actccagatc aagaatttat tcaggatgaa tttcaaccag tacattacca ttggtatgat 17700 agtacttctc aagatgcaat ccaaagtaaa gaatttttag gtgtcgaaaa gattgatagc 17760 atgtttaata gagtgacgtt taaagtaaaa acggtcaaaa actttaaaac tgaaaaccca 17820 tactttagac ctttcttata taattcttct ggaaatataa atacaggttc tcatgtttat 17880 atcaagaata tgagtttaat agagtctaat aaacctaatg aaaattattt aggtaatgta 17940 agttcttatt ctaaagaaga acttgtagaa gaaaatacat ctataacttc caacggatac 18000 ttagttgatg ttaattattt ctttattact gataaagttc ttaaagatag aaatataact 18060 ggaattgatt cagaagaatc tttatgtgtc aagaaacaat atagaataaa taatggtaat 18120 tggatagatt atgatgaaaa tactagaata ttaattaaag atgtatcgac agttgaagct 18180 agaaaagtca tgatagatgg aactattatt agagaaagta tggacattac tcctgatatg 18240 ttagggtata atcttcctat tccaccagta tttattggta ctgaatataa taataaagaa 18300 gaaggatata gttatttccc tgtagttgaa aagaacatgg gtcattctta tagacttgaa 18360 ttaaatggta aaccatttga gtttggcgta ccagtattgt ctaatggatc agttcaagaa 18420 tacgagaatt atgaaataac tgcttattct aagcattata aattcccaga tagagaagct 18480 aaaaccacta ttaactttag agctatgaat aaacctcctg aaaaacctta cttaaaaggt 18540 attcaagata aagagattaa tcatattaca gataagtact tccgtttaga attaaaagaa 18600 actgaagaaa atgtacagta tatggttaaa ataaatgata gaatagttaa tattggagat 18660 tatttatttg aggaagatga ttataaactt aatggagtat tcgttataac tgttattgct 18720 aaaaataaat taggattaac ttcttataat gcatattaca ttgataataa tagaaacgtt 18780 gctgatgatt atcatgaatt cgactatgaa cgtaatgctc tgatattaaa ctctagagat 18840 aaacgttctt acgaatttaa taacgaaatg ataatggatt tacgtactgg agatatctct 18900 tatacagatg acaaaggtaa tttaattgat ataactgcta agttaaaaga aagattaaat 18960 tacgttgaat ccgatttgaa taatattaat attaattcaa tgataatgag aggaaatata 19020 tcgctattat tagatgaatt aagttatata gttaagaata atgatttctt agaaaataac 19080 cttaaagaag ctatagacaa attagaaaat gttgaaaatg aagttaaaaa ttcagataaa 19140 ctaattaagg atatagaagc tcttaagaaa cgtgttcaag aatcaaataa attggttact 19200 acactttcta aatcagtatc taagaaaact acagaaataa atagtactat taaaactatt 19260 gagagagaaa ttataagtac tctaccagtt caaagagata atatctcaat ggtagctaaa 19320 tcttattata atattaaatc agtagacttg acagctagaa ctaagattag taaaactgca 19380 tttaataact tcaagaagaa atacgaaaaa ttcttaacaa atgttaagac atatataaga 19440 aacttttaat atttgaccat acattcgaaa cttatcttta tagaaaaatt aaggataata 19500 aagagtgtat ggtctttatt attgtaaatg aaagtcggtg aaattataat tgtcttatag 19560 aatgtttatt aaaccactaa cagaaaagac tggtgcaaaa cctgaaagac atgaagttat 19620 ggttaataca gaaacaggaa tgattagttt aattaactct gatggagaaa atgtttctgg 19680 tttaaaagat ataacagttg acattgctct taaaaaagaa atattaagtt tcttagatat 19740 agttaataaa gatgtagtag agtctattaa tgatataaaa cctaaatatg aaaatgaaat 19800 gaaaagaaca gatgtaataa aggcacaaat ggataaactt aaaagtctta ataaagatat 19860 aatagaacaa atcaaaaaga tagagactaa taatgtaaca gcatacgtta tgatgcaaga 19920 tttaattaaa cagatatata atattataga tgtgtattca aagacttatt tagatatagc 19980 taaagtagaa agaaaagtag atcatttaat atacttaaga gacattctta gaaaaaatag 20040 aattcaaatg gaaaaagata ttaaatctct aactactaaa aataatgaag ttaaaaaact 20100 attggctact aaagaataca aatctactta tgatgcttgg gttgctgatt atgttaaacg 20160 tactaaagct ttatctaaag aatctaaagt aagtagtatt agctttagtc acaaaatata 20220 atataaggaa ggaggaaata cattgggtcg ttttcattat tcacctatag attataaaga 20280 ttatatgaat aaatacttta atagtcttca aacaggtgaa ttacttattg attttgaagg 20340 tgcagatata tatgtatctg aagaaggata caatatacca ataccgtcaa ataaaaaact 20400 taaagatgat attattaaat acttagaaaa tagtattgaa ggtatcaatt atagaactag 20460 agaaatacct agatttatta aacaaattga agaattaaga agaaaaatag aagaacagca 20520 ggatttaatg aaccgtcagt atgatgatat taatatgggt atagatgaca atatcaaaga 20580 tttaacttat attagtaaag taactgaaaa taatgtacag caattagggg atttaaaatt 20640 atctattgat aaaaatgatc ttaagttcat tgataaacgt ttattagagc ttgttaatga 20700 atttaactta attaatagtg attctcgtaa taaaatatat gtacaagatg ctcaaaataa 20760 atctaaacaa ctaactgcta tatggaatga aattaatgct cttatggatg atgctaataa 20820 aaaattatct aaaatgggtt ctttctcagg tactatgatg attaaacgtt cagtaactac 20880 tagaagaatg gcttatgatg cttattattc taaacgttta tttaacttta ctactaatgg 20940 tggtcatggt gatataggtt tcccatggag ttataactat gctagtaatt taagtactta 21000 tttagatttc actaaaagag ctaaaagagg tttcattaaa tggttttacg gtcaaaaata 21060 tttagactca ttaactagat taagattccc ggcttacaat ggttctggat tctggtataa 21120 aggttttgct actaaaaaag atgtacgtaa tggttctata catggtaaga gaaatccttc 21180 atgggattta tttgaaacag ttcctcttaa aggacaatta aatcaaactg atagaaataa 21240 ttttaattta ccttatataa gatcagctac aaattatact atgtttgatg cgggtaattg 21300 gtctggagaa aagaaaccta atacttataa tcatacatcc gttatagttg actctagagc 21360 tcctacttat agaataggtg gtagtcaaac gttccaaaga aacttcaaac atattggtaa 21420 aaaatatgat gtagacacta agttaataaa tcgtatagta gctaaagatg atggaactca 21480 aagaacacct agatataaat tcaataataa agatatgaat agttgtgttt ctgcaggagc 21540 acctactttc cctgttattg ttagggatat accttttata tcacatacag gtttccaaaa 21600 cagagaagga atggtaatcc gtatgggagt ttctaaatac gtatctcaaa ctgaaattag 21660 attagttaga atgaaattta ataatagtaa aggttgggta aaagcctaat taaattaagc 21720 tttcacatta acactaaaaa tattaatgaa aggacggtga atattttttg gcaagagaag 21780 gaatgactta tgaatatcct ttagaaatat cggatgaatt gatatataca aataatccag 21840 ttaatattat ggtaatggat gctcgtaacc atgctataag tttaaaagac ttagatcaag 21900 ttcatagatc tataggatta aaaatgtttg cgtatcatta ttatgtaact ttaactggta 21960 taatttatgg aggaagacct gaaagagctt taaaccctga tttaactaaa ttaactaaag 22020 ctctttatac tagtatgatt agtttaaatc aaagtccttt tgaaggtata gataatatag 22080 agatgaaaga tagaacttct tccatttctt ctaataagat actaatatgt cttgaaggta 22140 acacttctta taaagatatc cctaaagctc agaaaacttc attaataaca ttatgtaaag 22200 acataatgag tagaaataga aatattaaaa atgtgtattc tatgagagaa tatttaccta 22260 tgtatgagaa tttaggagat atggtagact ttgcttctat tagatctgaa gcaacaacat 22320 caataccgcc attatttgta actactccag caggtacagt tacttatagt tttggtaaac 22380 gtgtattaag atatattgag gataacccaa tgtctggtaa tgatgttaaa ttattggaaa 22440 tatatcttaa gaaattaggt attgatgtta ttcaacccaa tggtaaatat gatgttttta 22500 ctgttgatgc tgttagaaga ttccaaaaga gatataatct tgaaataact ggttcattta 22560 agaaaaatga ctttgacgta ttaaatactg aaatcaataa agttaaattt aagaacgttg 22620 taagtgatag ctattataga ttgttatatt acagagaaga tcaagaatta tacggtaaag 22680 atatagagaa tttaaataat agactaatga aaatattccc taaacttaaa ctaaataatt 22740 attattcaga agatgctgaa aatgctgtga aaagatttca agaatttact aaattaagtg 22800 ttgacggtat tgtagggcct attacttggg aaaagatatt tagttatgaa tttactgact 22860 taactgatat aattttctat gatccgagtg ataatgaatt taaactagtt attaaaatga 22920 tacaaaataa gattaaagat aatcttaata aatttggtat aactgaatat tcaatgcatg 22980 gaatatatga tgaaataaca tataaaaata ttaagaaaat aaaatcactt ataggtttta 23040 atatctctgg aaatatagat agagaaactt atgagttttt tgtagattta taaaaataat 23100 taaaaggatg attaatatga gtaaagaaaa taaagattta tttgtattcc aagaaggatt 23160 aaatgaaatt acagatgata tggaatttgt agaatctgaa gaagaaaaac gtaaacgtaa 23220 gaaaaaagaa gaggaagaaa aagctaaaag aaaaggagat aataaataat ggcaggtaca 23280 gctcaattta ctgaaatcat taatagccat cgtgctaaat taagtactat tctttcaatc 23340 aacttaaaga gtggtaataa tatacattta aaccgaacta ttgaaggtac tttacgtatt 23400 gaaggagaat gtgtattatg ggaagagatt aaatcaggtt taagaaaatc agatcaatta 23460 gttcacatgg tatgcgatat tgaagaaatc tcacatatca gttatgtaga cggatattct 23520 gaaaaggata gagaagaaga agatattcct agagtattaa aagaaactgt tgacaatatt 23580 gtaaataata ataaagctta aaaaataagg taatggcata taatttgtca ttacctttat 23640 tatattgcca aaatttaaag caatatttaa atatatataa tattaatgaa gatagttaga 23700 tattaatatt aaagttatta ttttatatag aataataaaa acaacctcca attgatttta 23760 ttgtactaca actatataaa atagatcata tgaatacgta tgatcttaat taaaatatta 23820 cggtcattac catataattg cggatccatt gagcctaggc tttgacgaag catagagctc 23880 attggatcct atcattatat tgtcggttta atattatatt tatctatctt cttaaatttt 23940 gattattata tgaattatat tttattataa agctatatct tattaaatta agataatcat 24000 atgaatacgt atgatttaaa tttatgtatt agcaaaataa tttttccaaa attattttct 24060 tatttaatag tatcgccctc tgcggggaat cttttcataa agcttcccgc agatggaatc 24120 taatcaaaca tgtttgttta taataaaata agatttttaa cttaaagttt ttctataatt 24180 aatttatagg cattatatga atacgtataa tgattattta tttatgtgta gaaatatgtc 24240 ctgatgcttg tcagcatctg ggcttatttc tcgattatat attgccagct cgtcccgctt 24300 ccttattact taggaagccg ccgagctgca atttatatat ttgttggttt aagttaaaag 24360 ttttaattcg atttaaagtt attctataat taatttatag acattatatg aatacgtata 24420 atgaaataat tatttataat cattgccata aataaatctc cacgttccag ctccttcttt 24480 aatattaaag aaggaggaac acaggatatc tatttatctt tgtttaaatc gaagttattc 24540 tctctattag ttattctata attagcttta tagacattat atgaatacgt ataatgattt 24600 tagaatcata acctattcat tatatttact ctgctttatt ttcggtgtaa tgattccttc 24660 attacactcc cagctgggac cattcttctc tcgttcgaag atcacttact ctttcatcag 24720 gtcccagcta aaataaagct ttaaatataa ttttagtatt agagaagaat atagaatgaa 24780 ttaaattcat tataataatc aactttgccg ttacctatat gattataggt aacggtattt 24840 attttttaat tttttataaa taggagatga aatggataat gtttaaattt aacaatgtag 24900 aacgtattaa cttaatagga aatagaaaaa tggattatat tgaattacaa gaatctttat 24960 atactttaaa acctaagttt aaaaagatag taaagaatga taaaggtaat tttgtattaa 25020 tattctcaga tggaagaaaa gaatatatta gtgatacaca tgtaggaagt atgtttagac 25080 ctaaaatgat ggtagttaat agtgttgatg attacaattt atctgatgga tatagacaag 25140 aatatagttt tgaaatggat ggtatagatt ctttaaatac taatttaaga agaattattg 25200 ataaaaatta tacatttaat attattactg aaaaatttag aatttatgaa gaagacaaaa 25260 tactcaattt aataaaattg aaatcaacga cagaaaatga taaagatata tttaaaattg 25320 aaggtatttt aaaaattaaa aaagatttga ttagtattga agacttagaa ttaattaaag 25380 atattttaaa tgattgttta acttcacaag aaaaatatga atatatatta aattcattag 25440 aacttttatt aaaatctata gatttaaaaa atagaaatgt taatacattt gatactttct 25500 atatacctaa atcagatggt actaaaagag aaattaattc acctatagaa gaaattagac 25560 ctattcttaa aaagcaagct agtatattaa atgctatttt agatcttaga attggtaagt 25620 ataatttaga tgaaaatatt atagcttata gagatggtaa atcaattaaa gataatgcag 25680 attatcacaa agagaataaa actattatca aatttgatat tagtaaattc tttgataatt 25740 gtcattttga ttattggaaa gaaaatctat tctttagttt taaagatgaa gattatgtaa 25800 tggaaagatt tgaagaacat atgaaagatt tattatttag agaagataat aaaggattat 25860 atatgggtag tccattatca ccggcagcat ctaacttaat tatggttcca gtaatgagat 25920 atattaataa tatattaagt aaatttaaaa ctgatattaa agttactgtt tatgcagatg 25980 atataacttt ctcaagtaat gaaatcaatg atgaatttaa tcctaaaaga ttaaaaagta 26040 tggtcaatca tgcttttaaa attaatggtt taaaatttaa acttaaagaa gaaaaatcat 26100 tagtgatgaa aaatcataag agaaaaataa caggattgtc tgtaaatcat aatgatgaac 26160 cgactatcag tcaaaaaaga tatagacagt taagaactat tattcattta ttaaataatg 26220 gagtagaatt taaagatatt aaaggatttg aaacaccact acaattagta tcattaatta 26280 actactattt agatgttgat actactgaaa aagttaaaag attaatggac aataatgaaa 26340 aaatatttaa tgaattaaag aaagaagctg gggtgaatta atatgttgga tataaataaa 26400 agaaaaataa cttcagaaag tattaattta aatttaggtc tatttgaaga tttacttgaa 26460 gaaatgaatt ttggtatttt agatgatgat cattttggat tagctattaa tcaattagag 26520 aatagacata tggtagaatc ttttaattat ttgaagagtg aaggtttaga agaattatta 26580 gaagatgtat tggtaaacaa taaaagtaat tcaatatata gtaccgaaag tttaattaat 26640 aatagatttc atgattatct tatgtttgtt aaaagatata atgaagataa tgaaaaagaa 26700 tctattatta atgatttctt aaagattaat gaatataata gaattgaatt tagaatagat 26760 ttatttaaat tctcttataa aaatatatta attgatatag acatatttct gttaatatta 26820 ttcggtaaag aattctatta tgagtacaga gaaaaataca ataaatataa tataaatact 26880 aataataaaa gtttaagaaa tttaattgtt aatacttcag aaaactttag atattatgag 26940 aatgaaggag actataataa agtaatcgat aaagataaat ttgttgatta tttaaacact 27000 actattaaaa gttatatagt tactctattt agagttttcg aagatgaaaa tataattatg 27060 gatgaaagct tattatatac ttttatatat aaaatgaatt attctaaaat tagaaaattt 27120 atttatgata ttgatgatgg taatattgaa ataaaagata ttcgaagaga atataagaaa 27180 tatcttccgg aaaacatatt gatttagaac tattgtatat agaagggatg acttaattgt 27240 catcctcttc ttttaatttt tttctaattt ataacaggag cggtgaaaaa atgagtaatg 27300 tcttattaaa agaatatgaa gataatatag ataaattcct atcagataaa aacaaataca 27360 atcaagcaaa aagatatatg gtaagttaca tagaaagaaa tactaaacaa ctttcttaca 27420 atactcccat atatagaatt ccctttaata tgcaaggaat agatgttaca actattatga 27480 aattagttga tataaatccc agagagatgg aaagagaaat taaaaaatta ccattaactc 27540 gtaaatatgc tgacgtatta aaacatccat tttacattac aatgtcttta ataatcagag 27600 gaattaataa gaaattaaaa gttagaaaga atgataaaaa cttaaataat gatttaagac 27660 tatttcttct ttacttgtca ttaagttttt attggtctat ccaagttaag caatttcctt 27720 atgaacctaa tgaaaatgtg gctcagtata caattaaccg attaagtaat aaattctttt 27780 tcaaaaaata taaaactgta tcaacatcaa taactgtaac agctgagcaa aacaatatta 27840 actcacttag tatattagat aaaggtcaag atgacgatat cctagtttat ctaatggatt 27900 taagaacacg tttaaataac ttagttaaaa actttgctaa agaactttat aaagatatta 27960 atgcaggaaa ttatctaaat cctcatgtag atgtgttgga tgatgaaagt aattatagag 28020 aaggtactaa catatcagga acagttagta atatatctca aaagacacta tctgaattta 28080 cacagaaaga tattaatatg agaatattaa aaatatcttg tagtatgact aatacaaatt 28140 caaatattat gagaaacact atgagtgata ttagacaaaa tgaaattaaa aatgtcaata 28200 atttattact taatatattg acagtgtatc ttgatggtaa aaataatcct atacagtcta 28260 taggtagtca aagatttatc agagaatcaa tttctttctt tactaagagt aatactaaag 28320 ataaaagatt attggagaat aaaaaaatac ttaatgattt tttaactaaa tataatagca 28380 aatataatca aacggaaaga gaagctacta aaaatagtta cagaaaaaca atatatgtct 28440 attttgtttt actcatatca aatagctatt aaattgaaag gattgatatt aaaatgagta 28500 acaaaaatga agatagaata gaaatgtcgg aaaatattaa taatgaaaaa ataaataaaa 28560 ttggcaagag gatgaaaaaa tttaacagtg taatgaatag taatagaacg tttatctttt 28620 cggtcattgc atgtttacta cttacttctt atttcatcta ttcttttata gataataacc 28680 caagaaattc tagtgcacct tcatctaatg cagaacagca gtatacttct aaagatgatg 28740 aaagagccat gttcctaatt caagaaacaa caaataataa aattagtatg ctatctgaag 28800 tagattcttt aatatataga gatgatttat caaaaaaaga aaaattagat tttttaagag 28860 atattaaagg tttaatagag cagaataata aaaattttaa tcatgaagtt aataaatttg 28920 ataaattgtc taaagacgct gttgatgata ttaaaagtat gaataaaata aatggaataa 28980 ctgttaaata tgttgatgat gcaattaaat ttaatgaagc tcctaaagat gaaaaaccta 29040 atcatgctag ggaaatcttc caaaacaatt ccaactttag aagcattctt gctagtatga 29100 attatactaa ttatgatgat gaacaaagaa gaatggaatc aattaaagaa ggaagatctg 29160 aaaatttaaa agataaaaat aatgagagta atgacaaata atatgtcatt actctttatt 29220 taccgaattt ttaaatatat attataataa tgtatagaaa tataatttct atatgtaaat 29280 aattttatta ggagagtgaa ttggataatg gcaaatttat cagacgcatc aggtactatg 29340 catttcgaag gcttcgaagg gaaagaaaaa ttcttaaagg aaatgaaaag attaattgtt 29400 aaatcttttt cagaaaaaga aactcagtat tacattaact ttcatcatga aattgatgaa 29460 aatgatgaaa taattgtcga tgatgaacta gaagagcaat ttaatgcaat aggccgttgg 29520 tcttttggat ctagtttaga aagattcttt gatagtattt ctagtgatat agttagatac 29580 tataaacatg aagaaaattc agaggaatta attaaagata atttagatta tattaaaaat 29640 aattttgctg aagatgaaga tatggctatt agatttgagt ttactgatta tgaacctggt 29700 atgaattttc tattagaagg ttttgtagaa gtcagacctg gtaatatcat taaagatgag 29760 catgggttta ttcgttatat ggaaactgaa acatctagtg attttactga tttagaagta 29820 aatgttgaga atctagttag tgaacagatt atggataatg aagacttcat tttaccagaa 29880 gatattaatt tcattgattc tgaagcttta cctgaagaag atgatttaga tattgaagtt 29940 gatgaagatc ataaaaagat ccgaagagag ctattgagaa gatacactga agaaaattca 30000 gtattctgta ttagtgaaaa tagaatgatg gaattaaata attaaaaatt taccctaacc 30060 ttaaattaat aaggttaggg ttattatttt attaggagat gaaaaaggat atgaataaac 30120 aagaggtttt taaaaatatt gaaaaagcta tagataaata tagaaaaaat tatatgtata 30180 attggtttaa gaattattta aatgatttag aatatgaaaa agattacatt gtatatggag 30240 atataggtga tctaggtaca atagaatttt taaatagata tatcttagaa agtaatccaa 30300 taaaaaacat gaatgaaatc aatattgaag atttattaca aaaaacaact ggaagaagta 30360 atatagtttt tccttacatg gatgttttaa atgataaaat actattagat gaatttaata 30420 taacttcata tgatagaaat ctaaaaagaa ttaaattata tattaaattc aatgatgata 30480 aatatctcaa taaagttaaa aatgaagaag aaaattttag agttaattct tttagcggat 30540 attacaatat ctatagtttt gaaaaagatc taaaatcttt tcttactaat tttaaagatg 30600 ttccagattt cttagagtat attaaagata aagaagaata taagaatctt tataaatatt 30660 taaacaaatt ggagagtgaa taaaatatga ctagaataga agaaattaca acaaaacctg 30720 atttaaatag ttatatgtct gaagtattta actatcactt tgaaagaata attaataata 30780 attatgtaga aagtatagct agtaatttcg ttgatattat ggaaaatgat ataaaattta 30840 gaaatgaagg tcaaatgaat cataaagata tatttaaaga attggattca gatggtataa 30900 aaaatattaa agaaatagag tcaattttat caagatttaa aaatgaagat aataaattta 30960 ttaaaaagat tagaaaagat attaatgata aaattgatta tactaagaat aataaagata 31020 aaagaataaa aaatgtattt aaaagtaaac ataatcttcc tacgtatatc ataggtaaca 31080 ttaaattggt taatgcttca gttattattc ctagaagtaa tttattttat aaaaatgaaa 31140 atggtattaa aaatataaga atttctttta gtccggataa tttattaaca ttcaatcttc 31200 atttttcaga aatatacgga gatgaaaaag taaataaaat taagagagac tttagaaaag 31260 attattcttc ttataatgaa acacctataa gtataatgtg taaaattctc gatattgatg 31320 atgaaaaaca agttttatta gaatataaat ttgatttaga caatatatat tataatatga 31380 caactgaatc taaaaataat ttaaacgaaa tgtctgattt aatgaattcc gttatcaatt 31440 atcaaatcca aataaagaat aaaaatttaa aaagtaccaa agtaattgaa attattaaaa 31500 ataatagtat catgagaaaa ttacaattgg attatgaatc taacaatgag aataaatatg 31560 aaatggaacc tattcctaga caccttaaaa aattattcgg taaaggagag aaataattat 31620 ggttaaaaaa atagattgga agtatactat aacaaagaaa tacttagagg atgttaaaga 31680 tctatatgat aaatttttag atagattcat taaaatatat aaaaatagtg ttgacaaaga 31740 tcaaaaaatt gaattagcta ataaaaatca tttctatatg gatattgaaa ttatttatga 31800 tcttatgaat gaaataaata atgaagaaga tataaaagat tttaaagaaa ttgctgattt 31860 tattaatgat aatcgatcag aatttatgag catttcagat tttaaaaata attctgaaac 31920 tttggattct atttatcata tgattgcaga ttataatgat ctctacaaag aacctaaaga 31980 aatattagaa attaaaaaat taattggtag taattcttta gattatatta ataatttaga 32040 tagagaaaat ttaattaatt taatagttga taaaagattt ggaaatacgg tttttttcaa 32100 ggatattgaa ttaaagagat tagttaataa ttttagaggt tattctttat atgataaaat 32160 attaaaaaat tctttattag gtttaatatc taaaggtgtt ttttcaaaaa gtattaaagt 32220 tcattttaat aatttaagag atgaaaataa taatctagat attgttagaa ttccagattt 32280 aagaataaat gataaagaat taaaaaatat ttctgatgat attgttgaga tacatcaatc 32340 atatcaattc ttattaaatg aacttaaaat taaaactgtt aaaaatttca atgaatttat 32400 taaagaaaaa ttaccaaatt taaaagtaga agaatttgaa atatcttcaa aagatttact 32460 aactgaagaa aaaattaaaa gtgaatatcc tagtctagat aaagatctta gaaaaataga 32520 caatattatt aagcaaatgg aattagttta aattatatcc catacctcta tttaaagggt 32580 atggggtatt ttattatttt tattatagga gagtgaaatg gataatgagt aaagaaatat 32640 ggaaaagaca cccaaaattt aatttattaa taagtgataa aggtagattt tataacgaaa 32700 gtaaagggta tatacacgta catgaatcaa gtaagcatgt aaacaatttg tgttatatat 32760 atttcgattc aaatactata aactgtgcta aagctatttt agagactttt agggaacaga 32820 aagatgaata ttataataaa atatacttta aagatggaaa tagagataat cttaacttag 32880 ataatcttga atggacttta ataacaggta gggatcctaa attaattgaa ggtattttag 32940 aagatattaa aaataaaaaa catgtggatg atatattaga aaaatataac tacgtatata 33000 gtgtaaaaac tatttattac ttaaaaaata attatttaaa agctcatgaa aaagctatag 33060 aatttgatga atctaaagaa aaatggaaac agactgaaga gaataaaaat attcttatta 33120 gtaactatgg aagattatac aataagaaaa ctaactatat tatgaaaggt agacgtaatg 33180 ctgataatga aaaagttact tattatttta ttgataatac ttcaagtgga gattatgaac 33240 atttttcagc attaaggtta gttgctaaat atttcgtaga caatccttat aatttacatt 33300 atatttataa tagaaataat gtatctagtt tttattataa agatttagaa tatactctaa 33360 acagtaaatt tactttgaaa gtttgtatgg agatgattaa aagattttta attaatgaag 33420 aaaaacctag tgtcatctct aaagactttg agatacatta tagtactttt aaaagtattt 33480 taaaagagta taataaaaga tcaatcgatg tatatgaata ttttggcata gaaaaagaaa 33540 atgaaatatg gaaagattat gatgaaatac tatcggttag taataaaggt agattctata 33600 ataaagaaag aaaagctttc attgagaaga aatttcgtga tggatttctt actattaatt 33660 acaataaaaa taatcatggt gcttcaaaac tagttgctag aacattttta ggtatagaga 33720 aaaaaccttt tgataaaatt atttataaag atggaaatgg taaaaatatt aatgttgaaa 33780 atatagaatg gtctttattc aaaaatcttt cattaaaaga ttgtaaagag ataaaagatc 33840 ttaaagattt aggtacttca gatgcaaaaa taattagaca atataaaact tcaccgggta 33900 ctataaataa aataatgaat tattataagg aaggtgtttt aagtgataaa aaataaatat 33960 tataaagcag ttttatctaa taaattatct aaagaaaatg atcctagata tgtaatagta 34020 gataaaaata ataaagtatt agatgattcc aaaggtaatg gatacactac gaaacagaaa 34080 gcttatcgag gttattcatt taaacaaaag aataatgaag aaattaaaaa gaaagctatt 34140 aagaacagtc aagataaaca agctattaaa aatgagatta aaagatttct aaaagaaaat 34200 cctgaagttg aaagggatat ttttaatctc gaatttcaat acaaatcaat gggatatgat 34260 ttagatgaac aagacttgaa agaaatatta gaaggtaatt tattatcttt caataaatta 34320 ttttttgatt ccaaacaact attagattat ctatctaaat aaaaaagaga aggaatgaag 34380 ttaaatgtca agtaattatt caggcagtaa tattaaacat ttagaaggat tagaagcggt 34440 aagacaccgt agtgatatgt acgttggtgc aattgatggt gctttattcc atatgactaa 34500 agaaattcta gataactcag ttgatgagtt catcaatgat tatggaacta aagtagtaat 34560 tgatttagat ttacaaaaag aaattatcac tattaaagat gacggtcgtg gtttacctac 34620 tgatattcat ccagaaaaga aaatacctac aattgagtta ttatttacat ctttacactc 34680 gtcaggtaaa tttgataaga atgcatttaa agtgtctgca ggtaaaaatg gtgtaggtgc 34740 atctgtagta aatgcattaa gttcatatat gatggtaaaa tctattcgtg aaggttatga 34800 atactatatt gaatttgaaa atggaggtaa aattaaaact ccatttaaga aagttaaaac 34860 taaatatcct aagagttatt caggtacaga agttacattt aaaccagatt ctgaagtact 34920 taaagaatac gttaagttcg ataaagatca aattagagat aatttaattc aaagagctta 34980 ttgtaatgct gacttgagaa ttgaatataa tgtaattgat gaagatggta aaaagaaaaa 35040 tgaagtattt cacttcccag aaggaattga agctttagtt aaagatgaaa ctaataaacg 35100 tctaactcaa gtatatcact ttgaaaaaga aattgatggt gatgtttatg aggtagcttt 35160 aacttacact aatacagata aagaagagat tgtttcattt gttaatggta ttcaaacagc 35220 tcgtggtact catgaacagg gtttaaagac tggtattacc actattatta ataaatttat 35280 tattgataat aacttattaa ctaaaggtat agataaatca tcaattactg gtgacgatgt 35340 tcgtgctggt ttatttgctg ttattaactg taagttaagt aatccaactt atagatctca 35400 aacaaaggat gatttaagta acccagaagc gaatagtaat atgcgtaaat taatgtctga 35460 taaattcaaa ggtattgttg aagctaatga taaagaattt aaaacagtcg gtaaacgtat 35520 tgtacagttt gctaaaggta gattgaatgc tagtaagtat cgtgaaaaag tagtatctgt 35580 taatagtaat aatgcaggtt tacagtttag tcctaaattt acagattgtt tatcaaacaa 35640 tcctgaagaa actgaattat ttatagctga gggtgattct gcagtaggat ctattaatga 35700 tggacgtata gctgaaattc aagctgtatt cccgttaaaa ggtaaaccta aacaatctca 35760 ttcaagttca ttaacttcat tattaaagaa tgatgagatt agtgaattaa ttaaaatcat 35820 atttggaact aacgatgtta aaaatataga ttacgataaa gttagatatc ataaaattat 35880 aataacttct gacgctgatg atgacggttg ggtaagattt atttaaaata aaaattagta 35940 taatatattc ttttcaaaga aaggaatatt ttaattatga caaaaagaaa aaccatagag 36000 caatttaaaa aagatttaga tgataaaaaa ggtattggag aatatgatgt tttatccaaa 36060 gaatatataa ataataagac tcatataaaa gtaaaacata aatgtggttt tatttatgaa 36120 gttaaaccaa atcatatatt atataaaaat aattgtcctc aatgttcaat gaatgttaga 36180 gtgtcatcat taaagaaatc aaaaaatata gacccggaaa attatttaag aaaaattact 36240 gaaggttttg aagatgaata tgaatggtta gaagaatata aagggaataa taagtataaa 36300 cataaattat tgcataaaaa atgtaataaa gtgattgatt ttagacctaa tgactttcaa 36360 caaggttata gatgcactaa ttgttattct agttcttcaa gaaaaacacg tttacttaat 36420 agatttttgg atgaaaataa tatacaatac caaagagaag tatcatttaa tggtatatct 36480 ggaaaaagaa ttttaaaatt tgattatcta ataaatgatt ttattattga atatgatggt 36540 atgcaacatt ttaaagttaa taaaaatagt atttttgaag agagttatga acgttgcaaa 36600 gtaaatgatc atataaaaaa tgataaaata aaagaactta attttaattt cattagaata 36660 gattttaaaa ataatatgag cgatataaaa acaattataa aatctatttt agagaatgat 36720 aaagaaatga ttctaagaaa agttatagat aataaattat actactatga taataaaaaa 36780 gaaaaaatat ataatgaaaa aatatattat actaagatga ataaagatta ttttaaataa 36840 attgtaagct gtctttaaac tttattaatt gctgggagtg ccttagagct taattaaatt 36900 ctaattaaga ttggttgatc agcatcggag ctctataatt tatattatgg agatacgttc 36960 aacgactatc gaaaagtgag cattatgtcg agaggaccta ttgcaatata actgagtaga 37020 gtacagccaa gtggtaagca ttgtgctttt aaatggaaac ttagaggcgt gtatttaaca 37080 catatacgta agatatagtc tcaacattta gggaaaccct aaagaagttc ataagagaac 37140 tggtaatgat taacgaccat tgctgaagat tttgttacac attcaagctt tattaatcga 37200 tttattctat acgcatttcc ctgaattaat taaacgtggt tatgtatatg tagctcaacc 37260 acctaaatat tcatataatg aaaaaggtaa attccattat attaaaaatg ataaagagtt 37320 agtggatttt gaatataaaa tttctagtaa gaaattaaaa ttagaaaatg ctaatttaaa 37380 agatttaatt aacgttaaag ataattatct tgatatattt aataatattt gctctgatat 37440 gagtgtctct gacaaattct tagatagatt tattctattt aatgaagacg aagaagatat 37500 tgatgaagta ttagaatcaa tggaattata tattgacgat aaagataata ttactggtat 37560 ttatgataat atctggcatg atgttaattt agatgattta attaattcta ttggtttact 37620 aattaatgtt cttgaaattg attacctgat cgattttgat tatgacgatg ggaaagaaaa 37680 aggttcatta agtccatata acatgcttaa atttattaat aagaaattta aatttgaata 37740 taattacttt aagggacttg gtgaagttaa tgcaagtgaa ttatttgaaa caactttaga 37800 tccaaagaga agagatttaa taaaagttaa tgaatctaaa tcagacgaag ctattaaaat 37860 gcttgatgat ttattcggta acaaaacaga ttctcgtaga gaattactaa ataaatacta 37920 tcaaactgta tagtatctaa agataatgta actaagatga aaataaacat atattataaa 37980 aatgaggtaa tgacatataa tttgtcatta cctctaatat attaaaataa taggagatga 38040 aatggataat gtcaaataac aaatatattg acgtattgtt aaatgtaatg atgtcaaatg 38100 acccaagtta tggttctgtt gatgtggaag atgcttttat aagagagatg gagaaagatg 38160 atgaagtaat tattaatttg ctagatagaa atagattaaa ctattatgta gctaataaat 38220 tattaagtaa gctatattat aataataaac tatcagatga attaattata aaatatttta 38280 acaaaattgt tgatcttaat aaaaaccatc gtgataaaaa tgaattaatt tatagtttat 38340 ttaaaacgcc aaaaggatta gataaggatt ttaaatttag aaatcgtcta gaattattta 38400 aaatagtcga tagactcatt aaagacgata aaaatgtgga ttctggatat aatcacaagt 38460 attatgactt accaaaaaat aagtataata atgatttaag agttccttta tttaaaaata 38520 aaactattaa aaggacaaga gaagatctag atttaataga aaagcataat cttataaatt 38580 tgctacctat agtctatata tttaattgga aaatgttacc tgataaagtt aatgaagata 38640 taatttctag aataatgaat aatactgaaa aaattagtaa aataagttat ttattaaact 38700 ttttagacaa taaaggtaat agaataataa ataatgataa tcaatcaaat ttattaactt 38760 atttaaatag taaagaagga gtaactcgtt ttgtaaacga attaaaacag attaatggaa 38820 aagataattt caatattaaa atgtataaaa tagttgaaaa tttggatgaa tcattgaata 38880 ttattggtga cacttttaaa gatcctttca aaaaagaaat tgtagcaaat acttttaaat 38940 aattatatta gaggagtgga atttaaaatg aaaaaattat taatggtagt atttattgga 39000 ttgttaacgg tagctttagc aggttgtgga ggaattaaga acgaaataaa aggaacttac 39060 gcatcatcag aaaaagtcat tgtattagag aaagataagt atacattata cgttaaaggt 39120 gaacctgata aacctattga tgtaacttat tacgatgtca ttgatgctga taaccaactt 39180 aataaaatgg tggttgacct taaagatggt aaagatggcg aagttttcac tagagaaaat 39240 tggtataaac aaggaaataa aatggttatg gtaactgaag atggtagctc atttaatgga 39300 tatcctgaag atggtttaaa agactataaa ccatctgacc ctgaagatgt tgagtaggaa 39360 gtgataaata atgactagta tattattata tataatattt tcatttttat tactttatat 39420 aacaacgata actatattta taattggtat aaatagtttt aagaatgata gaaaatttgg 39480 tatttctatt ataacaatgt ctttactaag tataatagct ttaatatact taacatttga 39540 catgtttaga tttttataaa attaaaaaag agagtaggaa atatatatgt ataaagaacc 39600 cagacaagct aaagtagtat atattaatgc agtaactgat gatagaaatg aaattattaa 39660 attagatagc gacacaaaga acgtttattt gaattctaaa atgtatttat cattaaaatt 39720 taatgattta gattttgata caagtagttt aagaatattt gagagagaaa tgacatctag 39780 tgaaactgga aatccaatga gttataaaga atttaaagaa gatttattag ttgatggttt 39840 ctatgatccg ctagtagata gtacgataac tattacggac agtaattacg atcataaaat 39900 tgaaattaat gtatataata tttaatttag gatttgtata ttatggaaaa ttataaaaat 39960 aatttaaaag atatattgaa aatggaatat gaagtaagtc tttcagaaat cataaagatt 40020 cttggaagag atagtttacc attaatagaa tctattaaag aaagtaaaga tcttcattta 40080 ttatttaatg caatagatta caacaagatt agtaatgata tgataactga agttgtcaaa 40140 gaaattgtaa aaaataacat ttatgatgat gaaaaattga ttcagctttt aagtaaaatt 40200 tcttccgata gatgtgactt tttagaaaat aattttgaat ttgtaattaa agtaataaat 40260 gatattgata aaaacaaatt taaaatgttt ggaaccaaag ttttgcatgc aatcaatcaa 40320 cttgatttag attcaaagaa tgtagattta attatagaaa attatccgga catttttgat 40380 ttaatgacgg attgtatgac taattatagt tctggattta agataaaaga tgaaaagttt 40440 ctctctgtgg taatgaaaaa atgtgaagaa aacaattcat atacgtatat tgaaatgata 40500 ttaattttaa taaatgcgga tttaaagata ttagaattat taattaaaga aaattttata 40560 caaaacatag tggaatttat aaattctaca aatgatgaga tgctcatcct agtgaaatat 40620 aataaacttg ctaaaataat tctattagtt gataaatatt ataatatcag aaatgatata 40680 gttcaaaatt caaaaagcat tttaactcaa aatactttta aataaattta acatttagtt 40740 taaatatata ttataacaat gaagttatag taatttatta ctataacttc ttcaaaaata 40800 aactatatta ggagatgaca ttatgtcaga ggtaaaagta aatgtagatg taatcaatga 40860 agaaagagga gttactggta ttcgtacacc tcaaaaagtt ttagaactta gagaaggaga 40920 tttaattgac tttgtattct ctccaagtaa tcgagaagaa tttgaagaag atcaaatatg 40980 ttttattgaa caagatgtaa cagatgaatc tttatcaggt aaaattcctt ttagtgattt 41040 tgttaaacaa aaaggtaaat acaaaaaata cgaagttcgt aaagaagtaa tgatttatat 41100 tacttctatt aatgataaag gtccattaga cagcgttaaa attaatattg aaaagtaaaa 41160 taaagggtaa tgatcattaa tctgatcatt accctattta taataatttt tttaatataa 41220 ggagagaaat atataatgtt gacatttatt ggcaaaggtt ctgcttttaa cgaagaaaag 41280 gtaaacaatt cagcttattt tacagatgat aaaaataaaa atttatttat tattgattgt 41340 ggtaatacag tattcaatca gattaaaaga attaatttaa ttgaagagca tatagactac 41400 aagatttata ttttagtgac tcatgtacat gcagaccatg ttggttcatt aggaacttta 41460 attgaatatg tatattataa ttataacaag aaattaaata ttatatctat ggccgataca 41520 ggaattggag aatatttaag tagtttaaaa ttaagtaatg atctttataa ttatagacct 41580 gcagttgtaa ataataacgg atattttagt ttacctagtg atttccataa atttgaattc 41640 gatgatattg aaatattctt tattaagaca aaacatgtta ttaatcttaa tacttactca 41700 ttattgataa ctaagtatat gcttaaagaa aaaagatttg acagtattta ttatacttca 41760 gatacaatag aaacaccaga tcaacattta agaagactag aacaaaaagt taaaaatgaa 41820 attaatagaa gtattagtta ctattatacc gatgtatctt tcaaagaaga aaacaatgtt 41880 catttaactt atgatcgatt attaagtggt attaaaatta gccctatgga gtggttaaaa 41940 gattatcata aggattttgg cactaaatta aaattaatgc atattgatga taatagtatt 42000 gatataaatg ataaagaaga agaattaaat gagatattaa aaggagagta aaaaagatga 42060 ctaaagaaat ggatgaaata attaaaaatt tagagagtaa atatgttgat cctgatttag 42120 agaacgatgt ctactcagaa aggtattttt ctatagctat ggttgatggt ataaaaaata 42180 tatttgatat tattttaaaa gaaataaaag acaaagataa tgtatcagat attgaaagat 42240 tagatactga gagacttcaa cctagaaatt taatgtctaa agaaaatcct atgatgaaaa 42300 atttctttga tatagcttat gaagttataa tggaaaataa atctatgata agtgaagccg 42360 attctttatc ttcatctttt gttaatttta ctaacagaaa tagagtagtt ataaagatga 42420 ataaaactta tttaggtttc aggtatattg aaataatgag aaataatagt gggaattttt 42480 atatcaatct agccaattac gataaaactt ttaagcctaa cagtggttat tacgatgatc 42540 aactttgtat tacttttaga aataagacgt ttagatttca ttatctcaca tataattata 42600 attcataatt aacttctact tataataaaa tataagaaag aagtgtaaga gctttgtcac 42660 aagaaaaatt aaataatgaa gaagaatggt atgacgttaa aggatataaa ggaatactta 42720 aaataactaa atctggtaga gtaaagcgtg tagcagatat agttaaagat catagaggaa 42780 gaatgcacat agttaaagaa tgtgaatatg cattatttaa aaatagtaat ggtgctaagt 42840 actttactat gaattacaaa ggtaaaaaat atactataca agtacacatt ttattggcta 42900 aaacgtttgt aaaaaatcca aaaccatatg aatatgattc agtacatttc attgatggga 42960 ataaagaaaa tattagtata gaaaatttat gctgggttcc taaatcatat tttacttttt 43020 atcatagaca tagatatgat aaaggtctat ttgaaaagct aggaaaagaa atgaaatata 43080 tttaatgaaa gtgtatgatt tgcatatatt ggaattgtct taataataaa tactataaaa 43140 acaatattat ataatatatt ttaaaaaagg acgttatata atgggcgata ttagtaaaga 43200 caatttatat atttttagag caaaatgtga aagagtagtt gatggtgaca ctatcgatgt 43260 cattattgat ttcggttttg atgtgagtgc aaaaagaaga gtaagaattc ttgatgtaga 43320 tactccagaa agaggacaag ataattttaa agaagcaact gaatttgtta aagaacgtgt 43380 ggaaggtaaa gagttactat tacaaactta caaatctgat gtttttggaa gataccttgc 43440 tagaatttgg tataataatg aagatactgg taaagtatgt ttaaatgatg aattattaat 43500 gtctgatctg ttaaaaccaa attcaaaatg gaataatatg aacaatattt aaaaattacc 43560 taatacctaa atactggtat taggtttctt atttaagcct ttaaaaataa aatacattta 43620 aggaagttgg tatattttga ataagttaaa tttagacaat attgaagatt tatcattaat 43680 ggttaaaaaa ctaagacctg aaattgaaga atcgacaaat gaatttagaa tgatatctga 43740 attagaaaaa atatttatac aatacaatct taaaaataga attcttgaaa agtcttctga 43800 atttaatata tttgaattta atgaaatttt aaatggtcag cataataaag acgatgtgtt 43860 tagtttcttt gttaatttca aagatttttt agattatgaa gaagatatag atatctatgg 43920 tttaatagaa ataaatgtat ttgataatcg ttctcttaag gaagaaatgg atattcaaga 43980 attagacgat tttatggtac aaggaaaagc ttatatcata tcagaatctt ttaattttat 44040 tgataagaaa gttcctatgt attttggaga tttttatata ggggaatatg gtatgatgca 44100 aaatctagat ttcatgaagg acatatactc tgaagtaatg atgactataa atgacgaagg 44160 tttattataa acatcaaatt attcacacat atagatggag agatgttcac tatgaaaata 44220 ttttacaatt cttatattct catggataca ggtccttcaa tagattctta taattatgat 44280 ggaacatata ttagtcaaag tgaagattta acaacagcta gtttcgtatc tagtgatgaa 44340 ttcctcggat ttcttttaat ttcactcata tctatatttt tagtatcgtt tgtcatattt 44400 agaactataa agaacaatag aaagagaaag aaaaataaga aaagataaat attaaattaa 44460 cctaatactc taaataatga gtattaggtt aatattttta gaaatttgca ataacgagaa 44520 tttataatat ttaaaagtaa aggatgaaat agataatggc agaagttttt aataaagatt 44580 taaaagaaat agttcacgat aatatgatga tatattttaa tgaaattaac actaaccgtc 44640 aaataccaga tattagagat ggtttgaaac ctattcaaag aaaaatactt tatattatgt 44700 ataaaaatgg ttatagatct gataagaaat ttgctaaatc agctagaata gctggtgaca 44760 ctactatatt acacccacat agtaatgatg gtatttatga ttctgcagtt aatatggtta 44820 caccgttttc tatgaaccaa ccattaattg aaggacatgg tgcatttggt tctattacag 44880 gagcttcagc agccgcttca cgttattgtt taactggaga acatatagtt gatatgagta 44940 atggagaact tgtaagaatt aaagatatag tacctcatag tgaattagac agtgataata 45000 aaattgataa agttgtcatg gactttagac gtaaaccagt taaagcaatt aaattcttta 45060 attcaggtaa acataatgta atggaattaa acactaatgc aggtaaaact attaaagcta 45120 ctccaaatca tcctttatta accgtaatca aacatccaac aaaaggatta gatttcaaat 45180 ggaaaacaat ggatgaaatt gaaaaagggg attacttaat caacagaact atgattaaga 45240 atgatctcaa agattttaga agtaaaaatc ttaatgaaaa tgagaaagaa agctttaaaa 45300 aatggggaga aattctttct aataaatact ttaatagaac tttagatcct gaatatggag 45360 tattaatgag aagtattgaa actgaaaaga gccttcctaa taaagtgtta gaagcttgtt 45420 taggttataa aagagaattc ttattagagt tatttaaaca agatggattt attgtagata 45480 atattggttt agttatcgaa agtcatagta aaagattctt gcaagaaata gctactttat 45540 tatctcaatt tggtatttat tctgtgatat cattattcag tgatagtgat tatagattac 45600 aaattcaaga tattcactca cttaagaatt tatctaaaca cttaattaaa gatgatgatt 45660 tatttaaaga taaaattgat gaaattattg atatgtatag aaatttagaa agtaataatc 45720 catatcaagt tattccttat ttagatgaag tattagatga gagaaaaatg acttcttatc 45780 tatatccaga gttatttaat actagaaaga atttcttaaa taactttaat ttacttgaag 45840 aagaatacgg tattgaaatt gaagaaagag atcatttaat gttatttatc tctaaatact 45900 tagataacta tacttatttt gaacaagtag aaagtattga agagttggaa gaagaggaag 45960 tagtttattc tattaaagtt gatacagatg atcattcatt tatgtctgaa ggatttattc 46020 atcataatac agaaatgaga ttaaataaat tctcagaaag aaatttatta gataatatca 46080 atgataatgc agttaatatg gttaagaact ttgatggatc aatgttagaa cctttagtgt 46140 taccttctaa attaccttat gtattagtta atggttcatt tggtattggt ggtggaggac 46200 atagatctga tttgccacca cattctactg aagatgtaat taatattact attgacagaa 46260 ttaaaaatcc taataagaaa ttaaaaacac ttattaaaga taataaattt aaaccacaat 46320 ttccttatgg tggagaagca ttttgtgatg atttagagaa atgttatcgt acaggtaaag 46380 gttctatgtt attaagatct gtagttgaaa aagatgaaag taaaatgact cttacaatta 46440 aagaaattcc ttataacgtt actttgacta gggttaaaga agctatcaga gaagcacata 46500 aagaggaaca attagatggt cttaaaaata ttagtgacgg aactcaaaac ggagatgttc 46560 gtttaattct tcaatataca aaatcttctg acttagattt agcattaaat caattgtata 46620 aagttaagac aattacttct agagttaact ttgatgttaa attagtagat aataataagc 46680 tagtggaaac taatttatta ggtattattg atagatggat tgaatttaga caatcaactg 46740 tgaaacgttt taaatcattt aaaattaaag atttaagaag tcgtattcat attattgaag 46800 gtctattagt tgtattagat tctaagaata tcgatgaatt aattaaaata gttaaatctg 46860 gtaaaggtaa agaagatatt attgatgtag ttagtaagaa atttggtata tctcatgcac 46920 aagcttctta tgtagctgaa atgaaactat atacaattaa taatcttgaa atcaacaaat 46980 tggttgaaga aaagaaagaa aaagaaaaga ttgttaatga agaaatggta tacatgaaag 47040 atgtaagtaa actgaatgat cttattatta atgaaatgaa agaaattaag aaagataaaa 47100 atacacttaa accatctaga ttaactaagt actctgatat tgattttaaa aatgataata 47160 aagaattatt aattaaagat gaagatttca tgtgtattat tactagacaa aataagatta 47220 agaaagttaa agatgaaatt agtaaacctc aaaagagaaa tggtaaaggt atctctattg 47280 gtaaattatc agatggtgat attccattaa acatctttaa tgctaatagt aaagataact 47340 tattcttaat tactgataca ggaaaaatat tctatgataa agtttatgaa ttccctgaaa 47400 ttaaatcatt gaataacttt ggtaaagata ttagtagatt tgttaagaat gaaaagatta 47460 ttaaagcatt tactttaact gatgaagaat ttaaagatcc agatacagct tttgtagtaa 47520 caacagcttt gaataaaact aaaatggtta tggttgaaga aattaaaaaa tctggtgtaa 47580 ttcttatgaa attaaatgaa gatgataaag ttatcaatgt tcataatgta cattctaaga 47640 aaccatttaa tttaatagct atatctgaaa aaggtaatgc tattagattc tcaagtgaat 47700 taattccagt tcaaaataga aatacaattg gttcttctat attcagtaat acaactatta 47760 ataaagataa taaagttgct tcaactgtag ttgattctgg acaagataaa atgttaatag 47820 ttactcataa aggtttagct aaacaaatta tgactgaaga cattccagtt aaatctagaa 47880 tgattaaagg tgtaattgca gctaaattta aaaatgaaaa agattctgta atgtatatta 47940 gtatgataga tgatgaagaa gataatctat tattagttac tgaaaacaaa actattaatg 48000 tacctttaaa agaaatcaat acgtataaaa gaacaactta tggcaatcca gtaatgaaac 48060 ttaatgataa cgaattctgt atagattctt ctatcattaa acataattag ttgagaaaga 48120 agtgtattat atgaaaccat gtaaatatat tataaaaata agtaatgatt cttatctttg 48180 ctataagtat gatgaacctt tagaaacaac agataaaaag aaagcaacta gatttaatga 48240 gcttgaatta gcacaagaag aagtgaaatt aatgggaatt ggtgaaattg aaaaaattcc 48300 ttataaataa aaattaatca gggagatgac attaatttgt catctccctc atattattaa 48360 ttttttggta aattctcttg aaacaaccaa atattgttaa ataaaaagaa ttggatgtga 48420 aatatattgg aaaagaaata tattagatgt aattcatgta gttcagtaca agaatatagt 48480 gaagatatta catcttgttc agaatgtagt tctgagaata tttcagtcat taaatctcct 48540 attgatttag ttaatgaagc tgaagtatta gttacagaat ctgaaatgga tttcctatta 48600 gattataatg atagtcaaga gtatgataaa aatggtaaat cttgttggtt tgatatatat 48660 ttaattaaat accctagaga taacactcaa attaaatata ttgtattaca aaatcaaaaa 48720 ggtagagaag aggatatatt aatcgatttt gccggagata ttaaaggcgg aaatcctatt 48780 gtaataaatg atacaggaag tattaagact gtattaaatg atgttgatgg attatctgaa 48840 gttgttaaag ttagattctt aagtaaagaa tcaactaaga gaaaaggtaa agaagatttt 48900 ggtttaaatt cagaagaata cattagttat aataaagata aaaataattt ctataatgat 48960 gctaaattga gaactttaat taaagtttta gaatctatga ataatactct attctttgac 49020 agtaaagatg atatcattta caataaaata tttactgaaa ataatgtact taattcacct 49080 ttatttacta ataagactgt aatgagttat aatgaaactg aagtatataa gaattatgga 49140 gattataaat ttgatgaaag attagatagc gttatatatg attatcaaat agaaaatgaa 49200 ataggtgcgt ttactttctt atataataaa aataaagaaa ataaacctaa attcactgaa 49260 gataagagta gtgaaattta tgctacaata actccatcta tgttcttatc tgatgaattt 49320 agaatgttag acgattatgg tagagttaat ccaaacgtat tagcattatt atactttaaa 49380 atattagaga aaaaattagg tatcagatct attgaattag taacttatgt aaatcctaat 49440 aaagatgata taatgttatt ccctgtttct tataatggac aaggttacgt attagctgat 49500 ttccatttag atagccctat agtatttaag aatatggatg atgttaataa gtattgtgca 49560 tatcaatttg gatatgacca agaaaatgaa gatgataaag gaacatttaa attctcagta 49620 aaagaagttc ctgctgaatt cgatttccaa aaagctattt caagtaatat ggaaattatt 49680 gaaagattct tcatgaaatt caatgagaat actttaaatg aaactgtatt agaaccagaa 49740 tcaatcttaa atgaagctgt tggagataat aaaaagaaac gtcaagaaat acaaaataaa 49800 atattagacg ttatttcttc attagacaaa gatcaatcta atatgaataa atataaaaca 49860 ttctttgatg aaatgaatga tgaagaattc atgagatata ttaagagatt tgttaatagt 49920 aatgaaaact tctacattga agtattacct aataaatctg aagctggatt taaagaagtt 49980 gaagaagctt taaacaaact tgatgtacct atgaatgaat ttgtttatta tcgacatgat 50040 ggaaataaag atgatccttt aagaactaga tataaagttc cagtagggta tttacatgta 50100 aaacgtctac gtgtgaaacg ttacacaaga aagacaatga agattgttga ggattgtgtg 50160 gcataattta ttatgccaac tttttagttg aataagcagt atctacctat aaagatacga 50220 tatgctatta ataatactcc cgcatgtata agaagtgatt tttatatgtg aagccgggtg 50280 aagtcactat attttaatta tagtggttag ggaaatgtat atggttagga acacgaacta 50340 tttatgaatg tcctttatat attagtatta aatgtaggct taatactatg atttaattaa 50400 taggttatta aatctcttaa cggaatataa agggaacaga tagaacctaa gtacatttat 50460 ttacctagac taaaaggaac gtttgatatc tcataatttt ttatgagaag taagagagaa 50520 tatagtaccg ttgaagctat gataataagt agtgaaggga aagttcttag tcataaaaat 50580 cataaactct cccatatttt tatgatggaa agccgtatga ggtgaaagtc tcacgtacgg 50640 tttggtgcag gggaaaagag gtacgcttag tatactctta cctattgcaa taacagttac 50700 tttcgaaaaa gaatgcatac agtttagatg cttcaactag atcaatgaag acaggtcaat 50760 tgacaagttc tgataaagta gcaagtgtat caaatatgga agcttctgca ttgaaagcta 50820 ttggagctca agatatctta agagaattga tgggtccacg ttcagactct atgaatgcta 50880 agcaagaatt aaataaaaac atctctatgt atggatattc tcgtttagag gatttaccag 50940 atgatctttc tgataagact acattaaata ctactttcta ttatttactt ggtgctggta 51000 tagaatctga tttacttaaa gacactagac ctgattatga tcaagaagaa taataaatat 51060 atattataaa aatgaggtaa tgacattagc ttgtcattac ctctaatata tttaaataat 51120 aggagagtgt tttggatatg gaaaaagtta tagaaaatac ggtaaaagaa ttaagagaat 51180 tggcagtaaa agaaatagag ttttttggtg aacctgaaat aaacgtattt catattaatg 51240 gatatacact tataagctta agtagagatt tttatctttt cacatcagtt aaagatgata 51300 ataaagagat tttaaacgca ttattaaaag atgatttatt taattatttt gatgaatatg 51360 ataataaatt tggatttttc gtatattatg aaactgttgt agataaaaag acaaataaaa 51420 aaggagaatg gaagaatctc aaacaattaa tagatacttt tgaatgggaa aatggagacc 51480 ttttagaatt tgtaaaggaa gaaaatttat cagtgaatga gtcgttaaag aaaaaagaat 51540 taagagaatc tacagaagaa ttataaaatt gagtagaaca tataagtatc cttaagttca 51600 tacaatttat atgaatttag aaaggagtaa ctatatgatt acttggttaa tagctatact 51660 agtagtttta ttaatactag gtattatatt ccgtggaccc ctagcagtaa taccacctat 51720 gggatggtct ggaattgtag ttgcaatctt agttatatta gtagtatttt acctattcag 51780 gtagataaag aggtaatggc atattatatg tcattacctc taatatatcg caattaaagt 51840 attttcaagt atatattatt taaatgagat aatgattata ccaatcatta tcttttaata 51900 aaaaacagga ggtataaggt atgaaagaat taacaagttc agtagaaaag gcagcaggta 51960 caagttgggt gcgttagtaa cacatcaagt ttttataggg ttaggtttag ttttattaag 52020 tttaatcgta tttgctattt tgtattatgc atttaaaaaa ttaaatgtca tgaataactt 52080 atcacctatc attgtattgg tagttatttt agttattgga attgatttgg ctttattcgg 52140 atacggttta atgcatatat ttaatccagg atattatgca ttacaagaaa ttaaagaagt 52200 cattaaataa atgatttcaa tgaatcaata caataataga taataattaa aaaaagttat 52260 tatctattat tatttttaaa ctaggagagt gaaattgata tgaataaaga ttatgaaaaa 52320 gtaaagctaa attctataaa tgaaatattg ggaggagtgg atattgaatc ttctttatat 52380 agattttggg aaatatacag caagaaatat gatgaatatg tctatttggt ttttgaagac 52440 atagagtatg agaataatta taacaataca gttaatatca aagggatatt tagaattgac 52500 acttctgata aatctttatt atttgaagat gaatttacat tcaataatgt attggtaaca 52560 gattcagctg aggattttgg tattagagta gataactatg catatgatga tctaataaaa 52620 catctagagg aaaataaaat tatttaaaat tataggagat gaatagatat gagaaaagaa 52680 ttaagtgatt atattaataa ggaaaaattg gatgcattaa gtatatcttt acaaggagat 52740 gattttgatt ctttagaacc aaaagctaaa gaagaagtat ttgaaaaata cttaaaatta 52800 gaaaaattgc atgtagaatt tagatatgaa gaatcattga gtaaaattgc agaatctttg 52860 aaggatgctt cacgtaaaga aaccaattca gattcaagta atgtagataa agaagctatt 52920 ttatcagctt taaagaattt tgcacgtaaa atttaaatag agagtaggta aaacattgga 52980 tgaagtaaga caaatagaaa aatatgtaga tgtagaaaaa ttaaatgcta taagtaatta 53040 cctctttaga tgtgattttg atagtaatag ttctatggta ggtcaatcag gaagaaaaga 53100 aattttagaa gtttatatgg taatggatag aaatgatatt caacattatt tagctaagaa 53160 aattgaagaa aatggagata aactttgtaa ttctctaagt gaatttgaag aattaataaa 53220 aaggataaag gggatgtaaa ttaaaatgaa aaaattaatg attttaggtc taacaatatt 53280 tttaacagtt attttagcag catgtagcgg tgaagaaaag aaccctagtg aagaaaaagc 53340 aaaaggagat agttataaat taatatatta tgaaatttta aataatggag atagtgatta 53400 tcctagagta gaaattgctt atgaaaatag aattaaagaa gttcaatctg aatctattga 53460 tatcgataat ttaattgagc atgtctcaaa agacccaaaa gaaaaaccta aattagttat 53520 tgacggtgat gattatcatg tatatagaca accttatatg acttataatc aagaagacat 53580 tgaaggtaaa gtagaaagta aagaggaagt ggaaaaataa tgaaaaagtt ttctatgatc 53640 ctagtatcaa taattacatt attagcattt gttagtcaag atgtattagc tattggaagt 53700 tcaacttcca gtagttcttc atcttcttca tcagtcagct catctgcatc gagatcatca 53760 acttcatcaa gtatgagttc ttcatcagca agtagatcag ctatgcaaag tagtatgaat 53820 gctcgaaata gtactaacag tgcaagtaga aatagttcat tgaacagtag tatgagtaga 53880 aataattcat cattttcatt aactaaccca aatagtatgt ataatagaaa taatcaaatg 53940 aattcatata attcacagct tagacaaagt aattatatga ataatatgtt gatgtactat 54000 ttattattta atggtattaa taatcaaaat aacttaaaga aacagaaatc aattttaatg 54060 aatcaaatga ataaagatca aaagttatat acagtgacaa ttaaaactaa aaataataaa 54120 aagcaattgt taactgttac taaaaaggat tatgataaaa ttaaagaagg agatactgtt 54180 aaatattcta ataataaatt agaaataaaa taataaaagg gtgatcaaat tatgaaatta 54240 ataaaaacac tattaattgt aacattatca ttctttttac tgaccgggtt tagtaaagat 54300 gaaagaatta gtggagattt aattgataaa gtaactgaaa tagaatcagg tgatgagatt 54360 aattatttga ttctaaaaga tgaagataag ggaaagacaa aaatagatgt tgacaaagaa 54420 gtatttgata aactatcaaa aaatgatgac atagttatta atgaagatgg taaagtctat 54480 tcaaatggaa aatttattga ttattatgat ggagatcaaa cgccatatta tgtacttggt 54540 ataattatgg gttcaataat tatattagga tttatatcag taatcattat agatttattc 54600 ccttattcaa tataaagtta agagataaaa taatatttaa ctaggagatg aattagatat 54660 gacagaaaaa attctaaatt taaaaatagt agtgagcaat gatttaaaag atgtatatga 54720 tacaaaatta tctggaggag gttataaaaa taatgaaata atggtatcag aaaatgatat 54780 tttaaaaata aaattagata ttaaagatga acaaggtaaa gaattaaaat tagaagacat 54840 aaatcactta ataagagttg gatctaatgt taaaaatatt aaaagacttt ttgatagatt 54900 ttataaaata gatgaatttt ttgaaaaaga tggggaatac tatttatata aaataaaaga 54960 aaatatggac actcaatgtt taatgtttag cgtatacaat ttagattcag aaattgatga 55020 agacgtttta attgacatct ttatttataa tgatagtttt cataaatcag tattaggagt 55080 agttaataga tatattgaaa ataaaaaaga tgaagatata gttaaaaatt ttgtatctga 55140 tattagaagt gattttgatg aaaaagaaat tgaatataca atagaaaata ttgacgattt 55200 actttttagt agcaatgttt ttgatttatt aaattacgta catgaaaata gtcatactga 55260 tgaggttatt gattgttttt cagaggaaat tcaaaaatct ttaagtgaat cagtaagtgc 55320 tgaaagtcgt aatgaaaatt atacttttgc tgaaggtata aataatattt ttggaattgc 55380 aggattttct ctaacaaatg gcagtgtttt taaatttaat tacttatatg tataatatta 55440 atattaggag atgaattaga tatggaaaat aacaaaaatg aattaattag cagagagaat 55500 atttcaccag aggtttttaa aaaggttgat gaaattaata tacttgataa gaaatctatt 55560 attgagtatg gacatgaagt acaagataag ttatctaaag aatcagataa agtattaaag 55620 aatattaaag aaaatgattc taatgaaaag attaataaag tattagatga tatgttagat 55680 gtatttaact catatgatcc acaaaagatt gatgagaata tgaaacaaga agaaaaaggt 55740 ttcatggata aaattaaatc tatgtttaat aaaggtaaag aaaacttaat tggtaaagaa 55800 ttatctaaag ttgattcagc ttcaaataat atgactttca ttgaaagaca attaaaagaa 55860 agtagttctt cagttgatac tgcaaataaa aatttagata atttaattca atctaataaa 55920 gattattatg agaacttaag tgaatatatt gaagcagcta aatataagaa attagagtta 55980 acagatgaaa ttcaaaaaga tactgatgaa gttaaaaata ttgaagatac tggtgaaaaa 56040 caaaatcaaa ttcaattagt atctgataaa gaacaaggtt tagataatct tgataaacgt 56100 atttatgact taagtacatc attagcttta gcagaacaaa atgtatttga attagaaatg 56160 attaagaata tcaattatag tcttaaagaa aatattaata actctttagt aaatagtatc 56220 cctatctgga aatctcaatt aactaaagca gtagtattga ttcaacaaca acaatcaatt 56280 aaaactaata aagctattag agaagcaact tctgatattt tattaagtaa ctctaatatt 56340 cttaaagata acgcagttca gatgtataat gaatctaata aatcatttat tgatattgat 56400 gttcttaaac aaactcaaag taatatgatt gaaatgacag aagatttaaa acgtatgtct 56460 gaagaagctt ataatgaaag attgcgtggt tatgaagaac ttaaagaaat taaggaagat 56520 aaaaaagaat tagaaaataa gaaaatagaa atgtaagaag gtgtattatc acatgttaga 56580 tattttaatc tattcatttt ctggtttcgc cattgtagga ggttctgcaa tggcgattta 56640 taatggaaat aagttagtta aaaagaaaaa aagagtctca caaaatgaat taaaacttaa 56700 agatacagaa gaattaattg atctcaatga aactaaaata atggaaaaat taaatgattc 56760 ttataaatta gaaaatgctt ttgactgtaa ggaaagatac tacgctttac attatctatt 56820 gagtcatcca gaaatggaat tctataaaga aatagccact catatttatt cagctgtttt 56880 aaatgaaaaa actaatattg gagctgaata tactaaagat ttatttattg aagggaaatc 56940 ctatgataaa agattagact tattgacatt ctctttagta tacaaaaaag atagtaaatt 57000 tgaaattaac aaagaaaatg gaattatgga agagtttaaa gatttacttg acactaatat 57060 agaagattta gagatgctag aaagagaagg ttttatatat acgaaagatg actcaggcat 57120 attttataaa tatttatttt tcgggactaa aatactaatc ggtttagtta atttacatgg 57180 tgattattat ataactatta tagatgaaaa agaaaacgtt tatattaaag atatgaaact 57240 tggtgaagag ttggatgctt tacaatattt tgacggaaga aggtttttgt atcatccatt 57300 agatttcttt atattagaag atggcgaatt acaaatatta gatccaaatt catataattt 57360 agaacatgtt aacaataaaa aaataatatt tgatcctaag tcttatgatt cagaacctat 57420 agggaataag cgtataaact tatatcatga agacatagaa tttaaaaaag ttccttttaa 57480 cactgaagga ttattaaatt atttaaataa tgatgttaaa atagaaaatg atgattttat 57540 ttatcttaaa ggaaacaaag tggaaagaaa tatagataag aatcattggt cgaatttaat 57600 agaaactaat tatatgatga attatagaga taaaaagaaa ttcatgaaaa atattcataa 57660 taaattagtg gaagagaaaa gaatgaaaga tattgaagaa tataaaagtt actctgaaat 57720 agggagaaag gagtgaagat tctttgagta aagatttttt ctctcataat aatgtaaatt 57780 ataaaaaaga tttagataaa caacttgatg aagatttaga taaactttat ggacaacagt 57840 ctatggatat taatccatac ggtcataaag gctttgttaa caaagatgtt agagaagcta 57900 aagaaaaact tgataaactt aatgatgatt tgatgcgtaa aggacacagt gcaatgattg 57960 atactgattt aattctaaag gaaattgata aacgcaaaac tttagaaagg gaaaaattga 58020 atggcgttta tgacagtata tataattttg gttctataaa tcctgtaagt catagtcact 58080 atagacagct ggatgagatt aataaacgta atactaatat aaaaaataac tctcgtaatt 58140 atattaaaaa agatttagat gaagaagcat tgaatagaag acaatataga aatatgtgga 58200 ataaacctgt aatgacttat gaacaaaaat taatgaatag attagatgaa ataagaagta 58260 agaaaataac taataaaaat aaagaaagat atactgttga agtttcagca ataatgtata 58320 taacaagttg taaatttatt cctgaattta ctaaagatga tataattaat acttattttg 58380 atgtaaaaga aatgatgaac aaaaaagata aaatcttagg aaatggtgaa agtgtaaaaa 58440 atttcacttt aatatttgct aaagctatat ggtttttaag aggaaatatt aaagaaaaga 58500 gtataataac aaatcattca gcacatgcaa ttaataataa ttttttaata aaagatttat 58560 atgatcttag agtattttaa ttaggagagt gaaaaagata tgggaagttt aataggttta 58620 attgtgctaa tagtaaattc actattagca tcaattttta tttttagtaa cttaggaaaa 58680 atgggtaaat ttaaaaacag ttcatgggtt ccaattgaaa gagagataaa aaatagaatg 58740 aaattcttaa tgactattaa ttttattcta tttctatcat cattaatatt attatttaaa 58800 aatattatat cggctcaagt atcattatta tcaataatta tatttggagg agtatttata 58860 ttctttttat ttaaattgat gagagacaat cagtatttta gtaagagtaa taaattttat 58920 aatacagttt atatgatgag tctattttta ttaacaatag atgttttatt atcattttat 58980 aatctataaa agattaaaga aatatataag ttaaataaag atgaggtaat ggcaaattat 59040 atgtcattac ctccaatata ctataaggag agtttaaaat gaaaaaatca ttaataacag 59100 catcattatt aagtacggta atactgttgg gagcatgtgg aaacgaagga tcatcatcat 59160 cagagaataa agggtcaaac ttaaaaccag aaaagcaaga agaaatttat tctaaagaag 59220 caaaattatt aggtaaagca ataagtaatg aagatgctat ggatgattct acaaataaag 59280 tttcagatga ttttaagaaa tctttagaca gatatgaaga taaaactaaa aatttagata 59340 gcgtagatac tcaagttggt gatttaactt taagagttgg aaaatctatt gaaatcatga 59400 gtgaacgcat gtatgaatta gataagttca ataaagataa tccagataaa gaaatggaat 59460 acaatctagc tcttgttgat gttggaatta ataccgctca atctctagaa agtataaatg 59520 aagattatga atcaatcgat gtatcatata aaaatgaaac tatcggtaag aaagctaatg 59580 aagaagtaac tgatgtttta tcaactttcc cagcatatga acttgatgaa ttgatagatg 59640 attatggaac tggcattgtt ggaaatgatg aaacagatct aacacaagaa caacaaaaag 59700 tattatcaga cactaaatat cgagatgaac ttaaaaaaga agtaatgact caagaagaac 59760 cagacacttc taaaaatgaa tataatgaat ctgtgaatat gtttaataaa tttgcaccag 59820 aattccttca ttataaagaa gtagatgaaa tggtatcttc aacagaaaat aacaatatga 59880 tggatatcag aaatgctgtt gtaagtgcta atacagatgc tggagtagat agttatgaag 59940 atatggaaga agatgctgaa tcattagaag atgatactga gagtatcgaa gatgaagaaa 60000 gctcagatga cgaaggatat gatattgatg gctggtctgc agaatcttat aatgaattag 60060 tagatgaata taacgctctt accgatggtg aaaaaatgga tcacgtagat gaagatgtat 60120 ctaatattga atatgaacaa ttagaagaaa gagtcgcaaa attagaagaa taacggagga 60180 aattaaatga agagaatctt taaaagttta actctttata tctttttatt tgttttagct 60240 tctttaacct tatttttagg gtttaaagaa gctattaatt atatcatatt gggattatta 60300 actttcttat taatcctttc tttttacttc ttattaagtt atgcatataa tttaattata 60360 tcattatttg gatataagaa attaaaaaga gattatgata ttatagcacc taaaactaga 60420 tttttaataa tggtagctgc tcataatgaa gagaccgtta ttagagaaac tattaaaaat 60480 cttaaaaaga ttaattatga caaaagcatg tttgatatct gtatagtttc agataattct 60540 acagataata caacaaatat tgctttagaa gaaaatgtta ttgttgtaga tacgattaaa 60600 ggaagatttg aaagagaagg cgttggaaaa ccagcaggat tacaatatgc attaagggaa 60660 ttaggatttg aaagtataaa agataaatat gatttagtaa tggtattaga cgcagataat 60720 tttgttagtc ctaatatatt aagagaagta aattctcaat atatcgctaa aaataaacct 60780 gaagcgattc aagtttattt agatagtaaa aattatgaca gtatgatgtc tttagcatat 60840 agtgcagtat tttggactaa taataaattt attcaagctg ctaaatatag attaggttta 60900 ccgaattcaa tcggaggaac aggtttctca gttagatcag attatcttat tgatagtgga 60960 ggatttaact atgaatcatt aacagaagat ttagaaatgg aagttgaaat agttagtaat 61020 ggtggaagag ttttatggaa tgactttgca tctatttatg atgaaaaacc agaaggattg 61080 aaagtttcta tggtccaacg tttgagatgg gctaagggtc atttttatgt aggatataaa 61140 aatttctttc cattattaaa attattcgca aagacattta atattaaata tatagataaa 61200 atagttttcc ttatgacaat gggaagaagt ttacatttag cattaatgtt gttagttata 61260 tcattacaag gattatattt atatttaaat aataaaacag aaatcatcat aaataatttt 61320 cattatccaa ctgtattaca attattaaat gataatttct tattcttagg aacttttaat 61380 gctattctat taagttacag tttcttattt ttaccattat attctatata taataaaata 61440 aagagtaaaa atataattaa gaatgcaata tcatttttat attatgtggt aactgatttt 61500 atagttcaaa ctcaagctat atttgtttgg aaagaacaaa agaattgggt aagaactcct 61560 catgataaaa ataaaataaa aacagacaaa taatattgaa tgtggataaa taaataataa 61620 aggagaaatt gaatgttttc aataactata atattaatga tagcactact aatagtgcta 61680 tcatgttata cccataaatt aaataaagag aataaagatg tagatttaac cgaaaatatg 61740 cctagatatg ctatggcaaa cagaaatgct aaattaatct atattaaagc agattctaaa 61800 agttatttaa actatcagat taacgaattc aaaaataata aaagattcaa agattatggt 61860 tacgaaattg ataaggttga ttgggatgga aatattgttc atgagagtag agatagtgac 61920 ctcaaattga ttaaagatcg gagaagatga ttatgggatt aatagtcatt acattagcat 61980 ttactacact tattcttatt gtaattattc tcttacaagc aaatcaaata aaaaatatta 62040 ataaaaataa tgatagatat tttaacgaag acgaatttca taatagtcaa gatatttttg 62100 gttataatga aaaaggaatt atgggttttt taaatatgtc tttttcatta gtttcagaat 62160 atgataaaaa agaaagattg tatgcaggac attacttatt aaaaaatatg aatgcaaaat 62220 ttttgatatt tgattctaac catgaaacat ataaagaagt aacttcaaaa gaactactac 62280 ttgaaaaaga taaaagagaa tatctttttt caagacaaat agaaagacct aaattttatg 62340 atcattggtc taatttaatt caaactaata aaaaactcaa cattaagaac ttgaaaaaat 62400 taacgaataa atacgacaat attctaaaac aaaaatttga cttagaacag attaatgaat 62460 ttaaagatta tatggaagga agaattactt tatgacagta ttaataatat tatccataat 62520 gactttttta gttgtagcat ttggcattat tgagaaagat gttgatatcc ttgcaactgg 62580 agctttaatt gcatgtttgg cattgtttta cgtagctttt gggataatct aaaaagaaaa 62640 taaaaagatc ggagaaataa ttatgattat agcacctatt ttattgataa tatctgtttt 62700 tttaataata gcttcattga tatcttttgt tataacagtt ataaatttta atgaaggaat 62760 agtttcttta ataattgcag ttgcaggatt tatagttttc ttattatctt gtgtatttgg 62820 aatgataggt ttataaaatt aaagatcgga gaaaataatt atgggtacat ttttgggaat 62880 atcactctta gtgtcttttg gattaacttt aatcttcttt ttattaacag ctgtatttga 62940 tgattttgac atattattaa tgataactgt tatttctgct ataataactg tagtactatt 63000 tatatcctta ggtatatttg ctatacttaa cgaaagtcaa ttctattatt aagaataaat 63060 attaagagag gatggttaga tgtgaattta tttaatttat ttaaaaaaga agataaaaga 63120 ttagcattaa taagaaataa atttgatgaa gaaaaaatta ctgcagtaat cagaaaagaa 63180 ggtaataaaa ttgaagtgga atatttatta tttaatgatg aaaattgcat gatgagacct 63240 tcttattatt ctgaagaaga tcgtttagaa gtagaaaaca aaataaaagc tgttatggca 63300 tattatggtt atttagacaa tgactttatt atgtatgcag atgtaattta attatattaa 63360 aagaggtgtt taagtaatga taacgacata cattatattt tcaattttag tactaggatt 63420 agttaatatt atttcataca aaaaatcaaa agcaaaataa attaaaaatt ggaactaacc 63480 tttctatatg agaggttagt tcctcatatt tgattttttt tagaaataat tgcgttattt 63540 attatttcaa ttaatttatt tagaaggaga gatacattat attgataatt aaaatactgt 63600 ttttgatatt tttagtattg ggcaatattt tatttttaaa ttcattattt acaattatct 63660 ttaatgagtt tgatacatat aagagagaat taataatgaa tcttatatca ctgctatcaa 63720 tttttactgc attatggtta tactcattaa tttaaatcaa ctagaaaaat tttaatgttt 63780 ttaaggaaaa tttctagctt ttttataaaa aatttgttat aataaataac gttatagtat 63840 taaataattt ttggagagtg aatgttaaat gtcaaaatta actagcaaaa ttaatgattt 63900 gattaaatca aacccatcag tgtacggtaa agaagataat tacacgccta tgtatgaatc 63960 aggaattgac ttattggact atagaaatgg tttcttaaat actgttacag atgatgaacg 64020 tattggatta atgggcggta aagtaactac atttattggt ggatcaggtt caggtaaaac 64080 aacacttgct attcaagcag cagcaaaaat tgttgaaaaa tatgagaact caagtgttat 64140 tcattatgac tttgaagatg caactactga tgaacgtatt tatcaagtaa caggttggtc 64200 taaagaaatg aaacaagaaa aatacactaa attaaataaa aagattagtt tagattcagt 64260 agatcaatta attcgtggta tccgtgatac taaattagaa aatgaagaag aattcactat 64320 ccatacagac aaaattgatc cagaaactgg agaaaaagtt tcattcatgg ctccaacagt 64380 agttatcatt gactctgttg ctacaatggc ttctaaagaa attgatgata aagatggtga 64440 aggtggacaa atgaatgcca ctaaacaagc taaagataat acaacattca ttaaacgtat 64500 tattggttca tctacattaa attcagctaa tattatgctt attttaatta atcatattac 64560 aactaaaatt gatatcaatc catatgcagc tacacctaaa gaattaaact atcttaaaca 64620 aggtgaagca ttaccaggtg gtaaagcaat caactatatg gcgaataaca tgtttaagat 64680 tagtccatca caggctttag atccagaagg aaattctaat caagctaaat atggaattaa 64740 aggttttatc aatacagttg aagttattaa atcacgttca aatgcagctg gtgctaaatt 64800 tgatttaatc tttgaacaaa agaatggctt taataatgct ttatcaaatc tattgttctt 64860 acaaagtgaa aaaatgctta aaggtaatcc aagagcttat cgtattgatg gttatgatga 64920 tgttagcttt acacttaaaa catttatgga taaatatgag agtaataaag attttaaaga 64980 atactttgat aactatgtta aaggtatcta taaagaaaaa ttcttagcta atattgaaca 65040 tgaatctagt ttagataatg aagaattaga attagttgaa ttagttaata aatatgaaga 65100 tatttggtta ggttcagacg gtaattatta tgattctgat aaaaatgcta tagaagtatc 65160 taaagattaa tttttaaaag ggataattcc aatgaagata atatacttca ttggaaccct 65220 ttaattcaaa ttttggttca aatatatatt ataagattgt agaatattaa gagcatgata 65280 ttctacaaat atattcatta ttataggaga gtgtattaag atatgacaaa agacaaaaca 65340 caaagaatgg tagaaattga agataagcga agtcatgagt ttttatcaga acctctatta 65400 atgcctaacg ttaatagaac taatggtaac cgatcacaaa tgtttacatc tcacattggt 65460 caatgtattc aattaactgg agctgaacca cctttaattc aaactggttt tgaaaatcaa 65520 gtaggtaaat attcaactgg atacaagaaa gctaatagag attttgaagt tatttataaa 65580 tttgaaaaga ataagtacgt taattactat ttaattaagt acaaagataa tgatgaatat 65640 gatgtaatta ttagagaaga agctaatcac ttagctgaga agttcggaaa taaatataat 65700 aatgatgaaa ttgataaact aaaagttgga gatactgtta gtaaagaaac tgtattattt 65760 aaagatcaaa actatgatga agataataat ttccaatatg gtgctaatgc aacttctgta 65820 ttcttaccat tcaaaggtat gacgaatgag gacggaattg tagtatcaga atcattagca 65880 gagaaaatgt caagttattt tgtaaatgta atcaatatca ctatcaatac aaacgatatt 65940 cctttaaatt tatatggaaa tgaagatgag tataaatcat ttccagatgt aggtgaagaa 66000 gttcaaaatg gagtattgtg tgcaactcgt agattgaatt acgatgagat tattcataaa 66060 tttaaaaatg aaatgcttac taaaacatta gaagatgata atgcttataa agttcacggt 66120 aaagttattg atattgatgt acttaataat gaagatattg aaaaattaga aaatcaaaaa 66180 tattcagagc aatttgtcaa gtatattaaa gaattaagac acttttataa aacatttgta 66240 actgttacag atgatattgt acgtaaaaag aaatttagta atgacttaat tagaattcat 66300 aataaattta aaggttatat tgatgataac gctaaattag tttatgacaa taatcaattt 66360 gataaaatta tctttagagt taaagtttta gaaaagaaac ctttagttca tggatcgaaa 66420 atcaccacac gctatggggg taaaggagtc gtagctgaaa ttgtacctga tgatcaaatg 66480 ccaatgatca cagagttcga tggagaagac ttcactaaag attctactaa aacaccaatt 66540 agtaaacgag tagatttaat ccataataat atgggcatca ttaaccgtgg aaatccatca 66600 gctttaattg agttagaatt aaatcatgta tcaaatgtaa taagacatcg tataagtaaa 66660 ttagatgatg ttaatcaaca gaaagaatat ctattaggat atattaaaga tgtagataaa 66720 atttcatacg ataattatgt taaattattt aatcaattag atttatctga aactaaagaa 66780 gctattaatg aaattattaa agaaggtatt gtattacatc aagcaccatt ctttggcaat 66840 attgattcag aacaattaag atacgtattt aataaatata atattaagaa aaatagatta 66900 aatataagta atagaacatt catggttgga gatttatatc acttaaaact taaacatgaa 66960 ccgtctggta aattaagtgc aaaatctctt gactttaaca attacagtgg aattcctact 67020 agaactccag atagtaaaaa gtatctatca agaattaata acaatccact cagaattggc 67080 gagatggaaa catctaatat gatgatcggt ggatctatta aagcaatcaa tcaattaacg 67140 aatatgtatt caaataaccc agatatgcgt aaacgtttat tagttgaatt gtatacaggt 67200 aatccattta agatcaatac agagagtata caaaaacgaa ctcaaaataa taatactaaa 67260 gtacttaatg cttactttag tccattgaat gttagtatga catttgatga acctgaagaa 67320 gatgaattac tagatatcat ggatttaaat gaagaccaat tagaattctt aatggaaaaa 67380 tacgaaaatt tagatgatat caatgattta acacctcaag aaataaatgg tttagttaaa 67440 gaaattattg aagaaagtaa ataaataaat gggagtaatg atcattattt tgatcattac 67500 tcctatattt aaaggatgtg tttaaaattt atcctgatta cgatgaattt ttaaagaaag 67560 aattagaccg ctttggaatt gatacggata gtatgatgta tcattctgat cttaattaca 67620 attattgtaa agagaaatta gaatcaattg aaaaggaaga taaagaaatg gaatttaatt 67680 atttgaattt agaagatata tctttaaata aagaagagac aagtggagtt atgactataa 67740 gagaattagt aaatactatt gatcacttga tatatacaga aaatgaagtt acacctttat 67800 actacttctt tatggataaa attgattcac ttcctatgat taatatgatt acttataaaa 67860 aggcagctaa cacattctat gaagaatata aaagatataa cactgaaaat cattcagctt 67920 atataaatat taagggagaa tggaaacagt tatcatttaa tcaatttaaa gaatctttaa 67980 aagaagtttt attatcttca cataaagaaa gcaatgttga taaattattt aaagagttaa 68040 ataatttagc tgtaaaagat aatttttcat aattgctctt agatcaaaat tagtaataag 68100 catatattat aaatatgaga caatgttcat taacttgatc attgtctcat atattgtttt 68160 attttttata aataaggaga tgaattggat aatggaaaat aatacattaa attcgtatat 68220 aaaggaagat tttaaatatt ttaaagatga taaattagaa attgatgaaa tatttaactt 68280 taaagatgat aagactaaag aaaaatttga aacgtttttt aatggagtta tatacacatt 68340 gaaaaatttg aattatgttg aattatctga aatgtataat gaatcaatta aagagaaagg 68400 taatactcaa gttaaatctg aaagttatat aaattattta aataatgaat tgaaaaataa 68460 aagactaaat aaagaaacta aaaaacttta taaagattta ttaatgactt tagaagatga 68520 tttgaaaaga tataatgcta atttagatga cagcattata aataaattat tcaaaaataa 68580 gtatatatca atatcttatt atagtttaat agtaccgtat aatattgcta acgaaattga 68640 atttaataaa aactattata tctttcttga attagaagat tttgttaaat tcatagtatt 68700 tccgtattat cagcttttat acctatctaa aaataattta agaaatattt atataaagaa 68760 tacagatata aatcttcatg attattttat tgatataata aagagttata ttaaaaattt 68820 aatagataat aaagatgtag atacactaaa ggatttatta gatgtgttaa caaatgagca 68880 cgaatatcta agatccccaa aatatacaga ctatagaaaa ggtaatggta gaaatttatt 68940 tgagttgcta atagatatga atttcaatga atttaaagac ttattatatg aaatgatata 69000 tattataatg aataataatc taaaaaaaga attacaagta gaaatgaatt atgatatata 69060 caaacacaat atatttttaa taagtttaat gaatgatgaa gtagaaagtc atagacaacc 69120 taaatttaat gataaatttt taatagagag taataataca attagagcta ctgcaagtgc 69180 agatttatac agtaaaaata attactacca aaataactta ttaggacact atattaatga 69240 tctatatgta aataaaaata aaataaataa atttaaaagg gttaataaag ttagaagtct 69300 taaatctttt atttatttaa ctaaccaaag atgcattatc ggtggtgagt catattataa 69360 atatctatat aaatatttat ttgatccaag taacttaact agagaagagt ttgaagtatc 69420 tacattatta attaaattga taacttgtaa gtctagtaat caattaaaga aagttatgga 69480 gaatgcaaaa accaactcta tattaaataa tcttttattt gaaacagaaa ttaatgatat 69540 aattaaaatt ggtatagaaa tgaatattaa tactatattc aatgaaaagg gtttaagtaa 69600 aattaataca gttgatttaa ctgtaggaaa tattgtaaaa cctttgttat ataataacgc 69660 aaatgattat gaagaacaaa cagaaatcat taattcaata tttaaaaatt ttacttatga 69720 tatagatatc aattttgata aatatcatta caaagattta gatgaatatt ttgaaagtag 69780 attaaattta ggtcttttaa aagaatcaaa tatagatatt agtattaata ttaattatag 69840 taaaattgca aaaactattg taaataatat taaagataaa cttagaggaa aatatgattt 69900 tgaaaagaat gagtttatta ttacttatga taagatgaat attactcgtt taacttctac 69960 agagttctgt aatggtttat gtgaatattt aagtaaatac ttcccagaag aagctaaaaa 70020 gttaaataag agttttagag ctgaaattgt aaatacaatg tttagataaa aaggagaaat 70080 taaaaatgga tgttaaaaaa acgtttaatg cagatataat gaaaaatgat gaaaaggctt 70140 tcaatcatat tattaaaaat tgtatgtctt tttatgataa aagaaaaatg tataatgaag 70200 ttaatgatga caatgaagtt ttaacatata tatttaataa ccacaaagaa gaattaatga 70260 aaagaaataa tggtttaata gctatatcaa aagatctaaa agatcttatt agatacaccg 70320 ttgtcgatta ttatttatta agtttattaa gagatttttc ttcattttca gttgggtacc 70380 gggatattga aaattttgtt gagatgttaa aaatggagtt atttaaacca gatcaagaaa 70440 ctttaagtca attttcttca aaagatgata taatatattt atattataat acaacactaa 70500 ataaaataat aaaagttgat cctattatgt acttaaaagc actaatggag tatgttaaag 70560 aagaaaaaga attctatgga gatctatcta tagaatttga aaaagaagtt aaaaaatatt 70620 tagttgaaaa gaactttaaa taaaggagag atgatattta atgaatggat atggaaaaat 70680 taataaaaaa gtttttaata tagatcgtag caactttgaa gtagttttaa tggactacat 70740 ggacactaaa cagatgaaaa ataattataa tagggatata accgatcaag aaaaaattga 70800 tcggttaata cctttaatta aacaacaaga aaatgaacaa gatgaaggta gaatatttga 70860 aaatgctaga agatatgaac ttcttttagc taaaacattt gaatactctc ttaatggaaa 70920 attagaatta tacaaattaa aagaagtatt aaattattac gaagaaaaaa atctttttaa 70980 tatagtatat ccaaatttta gatacacttt taatgtagaa tctcccagta aagagtattc 71040 cttattatct ttaaaaacta aaatattttt aattatagaa actattatag attttattaa 71100 aaatgattat gtagaagata atctttctat taagttaatt ttaaattcag aagaaataat 71160 gattgatacc cttgatttaa acgaaaaatc tttgtgtaat acctttagtc tacaatatac 71220 aaatgaattg ttatcttata atggagatta tttgttctca catgatcaaa taaaacgtat 71280 agaaaatata aataatattt tatttaacga tatatacaaa gataaagata aagaaatttt 71340 agaattttta tctaagaaag taaaaaataa atacatttca aaatatttta aataaacagg 71400 agtgaatagg atatgtcaaa tttaactatg caagaaaaag acttaattat gattgaaaat 71460 aagtataata gatttttaga taaaaaggaa aagataatga ataaagaaac agactttatt 71520 aaaattgcat ttgaagaatt aatggacttc attgtacatt ttggtcataa taaattcttt 71580 aaatcagaca caatatttta tagagattat gatagaatgt tagagaatta taaaatagaa 71640 ttaaataaaa tatctaaagt ggaagatgat ttagtactaa cttatttaaa taaaattatt 71700 aatgacaccg ataaagatga attctatgat gaaatgaaaa gaatttcaga aagttatagt 71760 aaagaaaaat tagtcgtatc tatatcatat ataaaagctt tggacttcta tatacacatg 71820 atgcgaaatg aagaattaat gagtgatatg ggatctctta cagttcatcc ttatgatttt 71880 aataaacgat taataagtga atataaaaaa gataatatat tttggaaaaa actaagtgat 71940 gaagagaagt caaatgcaat tcaaatgtct aatatatatt ttgaaggtat tgaaaataaa 72000 gaaatcggta ggtctactac gaaatatata aatggtgaaa aagaaggaac tgtatttaat 72060 tttaatataa atacatttca taaatttttc gatcaatttg tatctttgga tatagcttat 72120 acagacggtt taatatttaa tttaatgatg aacagtaata tcagtaaata ttatgagaaa 72180 tactataaaa aaacagaaca tgatatcttc aatactagtt atatttctga taaatatgac 72240 tatgaaaact tagaaaaaga taaattttta aaaactttaa atcgtataga tatgttttat 72300 gatataaatg tacctttata tatttataat agtgaagatt tatcaaataa aaaatactat 72360 aattatctaa ctgctatgaa gtcttttgct ttaaatgatt tggttaatcg ttattatgat 72420 tcttatgaat atatagaata ttttagcgaa gttaatgtca atgattcttt cacgttagat 72480 atgttaagtg acgatgatga aagtgaatca aattattttg aagaattgtt taaaaaaata 72540 aagaaagaaa atgaagaaag acaatggtta caagcttttt aaaatttatt taaagagaag 72600 aggagacaat ttatgatatt tttaattggt atattagtca ttattttaat ttggttggaa 72660 ataatatcat tttctttatt tatatcaagt ctgataagtt taccattttc aatatttgac 72720 acaggaacaa gtgattttat taaagaagat ataataacag cgtttctatc aggtttatct 72780 accgtcataa tctttttcat attatcatcg ttctaataaa aaggagagaa cattatgttt 72840 gctttattgg gaatattagc aataatattt ttattattaa tatttatagg tttaccttta 72900 tttgtcatgg gagtagcttg catatttatg tcactttatg aaatctttgt agaaaaagaa 72960 aaagatattg atatgctact gacatcaact tatataactc tcggttcatc aatggcatta 73020 ggtttagcta tctttatatc attttgtgtt gaaagcatgt aatcatttaa aataaaaagg 73080 agaaatatta tgttaaaatt taatgaaatt aatgaaagta atttagatga cgtacaaaaa 73140 tatttagagg agcaatctta tgtatattat aatacatcag atcaaccaga attaactgat 73200 gaagaatttg acaaactatt aagagaatat gaaaagttcc gtccatttaa tggcggtgct 73260 ttaccttcta aaggtaaaaa attagtagat gtttcacatg aatatcctga attagtagga 73320 acagtttcta aggttaattc agttgaagaa ttagctgaat ggattgaaga aaaaggatta 73380 attaatagag aattattaat tacacagaaa tatgatggta attcagtatt agtcatttta 73440 actactaaag gagattattt agtaactaaa tcagcattaa ctagaggtaa agatggtaaa 73500 ggtgctgact taactgactt cttcagtcat attaaaatta aaaaatcaga tgtaaatatt 73560 aatgcagtcg atttatctga agatgatatt gatatcgcta ttaagtgtga agcagtaatg 73620 agttatagta actttaataa gattgatgaa gagtatgcta accctagatc aatcgttgca 73680 ggattattaa actcagatga tggatataag aaacgtaagt taattaattt attaccattg 73740 agaatcaata ttagtaataa agaattaact cgacaagaag aattgaattt aatttcagca 73800 attactagtc atagtactgt atttgatcaa cttgatccac agtataattt tgttatggaa 73860 gatgaacacg attataaaga ctttaatgaa ttatatcatc aaatagctga tgaaagagag 73920 tattatgaat acatgattga tggattagtt attgaagctc ttgatgaaga tgatagaaat 73980 cgtttaggca gattaaatga tcgtaataag tttgatgtag cattgaaatt cccatatatg 74040 actaaaaaga ctaatgttat tgatattgaa tttgatgtat ctgagaacgg aactggacgt 74100 tacacacctg tagttagatt tgaacctatt tattttaatg gtgctaaatg tgaaagagtt 74160 tctatttcta actataaacg ttttaaagaa cttcaattag ttaaaggaca agaagttatt 74220 attgaatatc gtaatgatgt tttgagttat ttaactccat ctcctactaa cgaaattact 74280 ggagaaccta taccgttcat taaagagtgt gtatactgtg gtgaagaact tgaagttaat 74340 gaaaatgaaa catttgtatc atgtattaat aacgattgtg aatgtagagt attaggtatt 74400 attaacaact atgtagataa aatgagtatt aaaggaattg aatattctac tattaataag 74460 ctttataaag gtaacaaact acctaacgga atccaaagtt tatatgaaat tgataaaaac 74520 gatattatgc aagtagatac ttttaaagaa aaatcagctc agaatattat taatacaatt 74580 cataaaaata aagaatatta tgactatgat gtattaggtt cattaggatt aaatggagtt 74640 ggaagaacta catttaaatt agttactaaa gtctatgatc cacaagaaat agattataca 74700 gatttaagta ttaaagattt aacttctatt aaaggaatcg ctgatattac tgctgagatt 74760 attattaatg gttataaaca gaataaagat ttaattgaat tcttatttaa tgaattggat 74820 gttaaatcac ttaaaaaaga aatggaagct aataaagatg attcagttga gccaatgaat 74880 attgtattta gtggatttag agatgctgaa tttaaagaac agttagaact taaaggtcat 74940 aaagtaactt catcagtttc aggtaagact gatttattag ttactccaga tccaaattca 75000 ggttcatcta agattaataa agctaaagaa aaaggtatca agatcattga tattgaaagt 75060 tctaaaggtg agttgttata aatgaaatat tataaggtta attataatgg tatattgaaa 75120 atattgaatc tagatgattt tgaagatgat agaattattg aaacacttag taatattgag 75180 ttatatttaa aagaagatga agaaattaga ttattggatt tatttaaaaa gccaactata 75240 gcaatggaca ctcgaattac aaaagaaaaa gataaccttt atatgaatgg tcatctcttt 75300 ttagaagttg agaatgcatc atgtaaacta tggagttacc atattaattt aaatggtgac 75360 gaaacattaa atgaaatata tgaaaggata tataacggat atgataaaaa tttctctttt 75420 aataaaatga gagaagatgg tctattattt ctatatgaat atgaacatta tacagaaata 75480 tctgaaaaag aatataaaga aaataaagtt aaagaaaatt ttaaataaaa aaggagattt 75540 taaattatga aatattacaa actaacagac agaggtattg cggatatatt taatattggt 75600 ggaatggatt atgaatttat ggatttctat gaggacaata atcacatatt cagaaatgaa 75660 agtctttatc taagagagga tgaagtaata cctctcttca gtattattga atatgatgtt 75720 actaaagaat gtgtaataac taaagaagaa ggcaaattag tcgcaaaagg taaaactaaa 75780 atagacgtag aagatgggta tgctgattta atttccattg atttagattt taatgaagat 75840 aatacaagtt taagcgattt atataaacag ttagaagagt actgtgaaaa tgaaaaattt 75900 gtagtgaaag atcgtataga aaaacttttc gagggttctg attataaagt tgtcactgaa 75960 aaagaatata aagaaaataa agttaaagaa aattttaaat aaaaggaggt attaaattat 76020 gaaatattat gaatttaata aaaagggaat tattaaaata ttaggattgg acacagctta 76080 tttaaaagaa gatgaagata tttttagaga aggaaatctt tatttaaaag aaaatgaatc 76140 aataaagata aaagatatta taacaaataa aaaagatatg gagtttaatt gcagtattta 76200 tgaagggtct gaagataact cattaatgaa agctaattta actttcagac atggatcggg 76260 acaactttta ttgaatattg aatatattga tttaaaagaa ataaaagatc gcactgttga 76320 agaagtttac aaatacgcta aagatttagt tttaaataaa acattttctt ttaataaagc 76380 tgaagagctt ggtatatgtt tatatgaagg aaaagaatat gaagaaatta ctgaggaaga 76440 atataaaaaa tacaaagtag aaaatacttt taaataatgg aatgagttgt tattgttatg 76500 gaaaaatatt ataaattaac agcggaaggt atatttgatg ttttcaaatt agataaaaaa 76560 cacattatat tcccagaaga taaaaataca ataatagatt tcagatcaaa ggaagaacgt 76620 atagagaaaa ttaatgaact tatatacttt aaagataatc aagaaataac aataaactca 76680 ttatctaatt taacagacaa tatcgtaata gataaatcag gttctaaata tacatttaac 76740 catttaatag aaatatcatt cactactttt agtcataaaa aaagatataa caaaacaatc 76800 aatgtaccga atgtatttaa aggaactgta agagaaaata gtagtagaag tgccttagat 76860 ataccgatag atatcaacaa tattgataaa atagaattaa catttaaaga atatagagat 76920 ctagtaataa aagaaacttt taaataataa ggagatttta taattgaaat attataaatt 76980 aaataaggat ggttatatta aatttttagg gttagatgtt ttgcctggac ttaaaacctc 77040 aattgttgaa aaagaaataa aaaataaaaa cttcattgtc aaatattgca atggagcaga 77100 tttttgtttt acattagatg aaattaataa aatgaaaaac aaagatattt accctaaact 77160 tggatttgaa agtctaactg aaaaagttaa tcatgaaata gaaaataatc caatagtatt 77220 tgttaataga aaatatgaag atgctaaagc tttaattcat gtagatttaa ttattaataa 77280 tgaagaaact acattaatga ctatgccaag atttaatatt aattttttaa atcataattt 77340 gtatatggaa cactttgatg aaataacaga gaaacagtat aaaaatatta tggtaaaaga 77400 ttcatttaag taaaactcaa tttaaatata tattataaaa ttgtgaaaga tgtatgatac 77460 ttatacatct ttctaaaata tttatttaaa gagaggtgaa aaagataatg agttctaatt 77520 ttgattatta tatattgcaa tcgagtattt cagaagctag aaaaaagatt aagaataatc 77580 tagatgtaaa tggatatatg gttataagac aaatattttt cagtcattta gattataaag 77640 attattataa tatgtatcat aaagtaaata atgtagaaga ttattacaat gatattatat 77700 tagaaagtat taaggatatt atatttgatg aagaaggtaa acttaatgaa gaagtagcat 77760 ttagtttaat taaaggttct aattcgaata tatgtgcttt aattaaagat aataaaggta 77820 attacaaaat ttataaaaaa gataaatatg taattaaagc tatagaagat ttattatctg 77880 agaaagatta taaaagaata ttggttaaaa atacttttaa ataatttgaa agtggatgca 77940 acttactttt attatattac aagtgagagt tggtgatttt attgataaaa atgcatttaa 78000 taaactttca aaaaaggtct atgaatagtt ataagaagaa tttaaacaca attgtacttt 78060 tcatagatta tgataaaaat attttcaacc aaattaataa tcaattagat atagatgtat 78120 taggtaatga tactataaga ttaaataatg ctaattattc attaatgtta gatgagaaga 78180 tttttagttc tgaaaggaca acaattgatt tctataataa aatagtaaat aatgatatat 78240 taaatattat taaagaaaat atatctaatg tagataatta ttctaaatta aaagaaatca 78300 ataatatgac tgatagtgaa tttaatgata ttattaataa agataattta tttaaatgtc 78360 aaaataaata cttcagtatg aataaaatac cttatataga aaaagaaata cctgaaagtt 78420 tttatctaga tcattttaaa gagattaatt tagattttat atttgagaag ctttttgaag 78480 agaatagaga agatgaagaa aaattaaagt acgtttatac tttagctgaa ttatttctaa 78540 cactcaaaca aggtaagaat atattttata attataataa agaggtagat aagaaatatt 78600 atagatctat atttataaat tctttattta attaatatga taagaaagga gagaaataat 78660 atgaagaaaa tatacggatt taaaataaaa tataataaaa aagtggtaga tactttcact 78720 tttgaaagtt ttgaagaagc tatgaataaa ctagaattat cattattaga aatttatgac 78780 tcagaagatt ttacaactat gcaattaatt ttaaacacat atgacattga agaaattaat 78840 gaagatagtt ttaaagataa attaagacta aatcatctta atcacattaa gaattttagt 78900 attgaattgt tttctaaata tattaacaat aataaggaag aaggaattgc gtaatgttcg 78960 aggaaagtaa agtaccattt tcatttattt ataaagaaac taaatacttc ttacacagaa 79020 gaaatattaa gaatttccct aatggagatt ctgaattctt attgtatgga gatgaaaatg 79080 ggaagtcatt cataatagaa gaaagtaaat tagaaaactt aattgaacaa catgaagttg 79140 aagtatctta cgaagaagat attatttaaa tatatattat taaattgagg taatgacata 79200 ttatttgtca ttacctctaa tatattaaac aatcaaagga gaaaacaatc atgaagaaat 79260 ttttagtatt accattatta ttcgttttat tattaacagg gtgttctcaa gctgataaag 79320 ttagtcagaa tatgtctgaa gaatcagata attttaatgt agttagaaaa gtaactgtca 79380 ttaatgcaat taagaatgat ataatattcc aaatgtctgg acgtatgtct attaaagcag 79440 acaaggaaga caatcaattg gagataattg tggaaaatga agatggtaaa tatcaaaaac 79500 atatcattgg tttatctgat aatgtttcat atactgttga agatgttaca actaagaatg 79560 taagtaaata tcaatatgaa attaattata atcctaaaat gtggattcct gcaaaaccag 79620 attataaaga ttaatataat agaatggaga gattgattta tgtctaagaa aaagaaatta 79680 gaaaaaagac ttaatgtaag aattaatcaa gaacaaaaga aagctatttt aaaacgtgaa 79740 gatattgata gaatggattt tgagttcatt acattagata aagagaaaca tgatgaagaa 79800 gaaaaatttg atatcaaagt aaaatctaac gataagtttt ctctaattat cattattaaa 79860 ttcttttcta aattgttgaa ttttagtatt aaaagagata agaaaaaaga aaaagttaaa 79920 gaagatataa aagatgataa tgaagtttct aatttagata agaaataata aaaatgccat 79980 aatacacaat ttaagtgtat tatggcaaat tatttatttt tcaggtttaa aacggtcttt 80040 aagtctagga tatagacgta gatgtgcttt acgagtagga tctgtaacaa caatttgatt 80100 tgttctagga tttctacgtt tacgcatatc ttcaggttta acttcaagga caccaatttc 80160 aggaataata gttttagttt gatcagcatc atttgcagat tcaacaatta tttctatcat 80220 ttcattataa gcatcaacta gttctctttg tgttaatcca gtacgtctag accattctct 80280 aaagaagtgt ttttgatctt gaatttgatt tagcatttta ttatttcctt tccatataat 80340 atatttttaa ttttttagaa aattgttaat attttactag cttttttcta aattttatga 80400 tataatattg ttatggaatt tcatagttgt aaaaaaataa ttttttgcaa taacttaaat 80460 ttttatatgg tttcgaattt ttaattataa ggagagtcag atatcgttgg gtaattattt 80520 aagaaaaatt acgaagaata tacaagatga ggtcagtaca aaagagtcat ttaatgagga 80580 tgtaatatac tttagggaga atgaaaacct agaagatatt atatctgata tttacaaatc 80640 agtagaattt attaaaggcg taaaattcat tgattgtaaa gttgttcctc caagtgaagt 80700 ttatgagtac aatcaaatga cagacaaaca atttaaagca agagatttta gaaaaatcaa 80760 cgtagaagaa tcaaaactat tagaagttca aattactgta gaatttgaat cagctgaagg 80820 ggaaaaagaa ttatacacac ataaattaga tttccctgaa cttatagaag gtcagtatta 80880 ttatattaat gataataagt tcttccctat cttacaatta gctgatactg aattctataa 80940 acctaaagca agtacagtag taatgaaaaa cttattacaa ccattatcag taaacggttc 81000 taaaaaagat gaacttattg atgatgataa gaaaatgcct aaaaagttaa gaggtagaac 81060 attatattta gaagtgttta ataaaaataa acctgttcca gcatttttat tctttattgc 81120 taaaatgggt ctagatgaaa catttgaatt cttagatatt aaagaatatt gtgaattagt 81180 agataccaac gatgaaaaag atgataaaca ctactatttt agaattaata ataaaataac 81240 tattcaagtt gataaagaat ggttagatca agacgataga tatagaactt ctatggtctt 81300 atgtattaaa gatttattta aaggtatgag agcaggatta gataaagtat atgataaaga 81360 attctggctt aagaatttag gatctgtgtt tagtggttct actaatgttg atactaaaat 81420 tgaaaaagct aattctatga ttttatcatt tgatagaatt ttagatagtc gtactaaaaa 81480 tatttctaga ttagatccag aagataaaga atcaacttat catgtagtta aatacatgtt 81540 taaaaacttt gataatctta atttattaga taatacagat ttagctaata aacgtttaag 81600 agtattagaa tacttaactt atccactgaa tagaaagaac tctgatacgt cttatcgtat 81660 gattaatttc acagataaga aacgtacaat taaaaatctt aaaggattat tctcaggtgt 81720 acctcgtgat ttcttattaa aaactatagg aacatctgaa ggaattagat attccaatgc 81780 ggttaataca attgacttat ttactagaat tcttaaaatg actaaagcag gtccacaaac 81840 tgctgttgat actagtaaac catctattag aactattaat atcaataata cttatttcgg 81900 tagaattgat ttaatagcaa catcttcaaa caatccaggt attacacgta cattaacacc 81960 attctgtgag gttaaagatc ctggtgagaa tggttcattc tattttgaaa ataaacctaa 82020 catcagagaa aatattgaca cagataattt agataaacta gagaaagaat ctgaagacaa 82080 tgaagttgta ttagatatta aagaaattgt agaagaggat gacgaataat ggctagattt 82140 ttacttaaga ataaagactt atcaaaatta ccagtagtaa caaatcatga atcaattgat 82200 aagaaaggtg atttcactga agacggtatc ttcagtgaga aaatctttgg acctgattca 82260 gatgtagata atattacaaa tgaagctata gtttatttag gtaataacta tattattaca 82320 cctttaggat atgacagaat taaaaaatta ataggtagaa aaagatttgc tgagattatt 82380 agttctgaaa aacctattga tgaaaatggt aatgtaattg aaccagaaga tgaccataat 82440 tcatatattg gtttagttga atttagaaag aacttcttaa agattcttaa agaagaagtt 82500 aaacgtgata aacgtaaaac taaagattac aatagagttg ttcaatggta tttaaatgga 82560 acattattcc aaaattatgt aactgtattt agccctaaat taagaccggc tacagttaat 82620 aaagcaacta agacatttag acattcagaa attaataaag aatttaattt attaattgct 82680 catagtaata gtcttaaaga attagatgaa cattatacag atgattcagt tgaactacaa 82740 aagttaaacc tacttaataa aattcaagat gacaacatga atatctatga tcgtattatc 82800 aatgaaaaca ttaaaggtaa aatgggtact attcgtaaat taattatggg tagtcgtgta 82860 ggatattcag ctcgttcagt aattgttcca gctcctgatt taaaattaaa tgaaattaga 82920 atgaattata caatcttctt agaaatatac aaaccactat tagctaattt aatgtatgta 82980 acggaaaata ttccattacc taaagcagaa gaaatattag gtagagcttt agataacttt 83040 aatcctaaag tatataaata tatgaaagaa ttagttaaca aaactgaagg tggaatgaga 83100 gtaattttga accgaaatcc atctatctca gaatcatcag ttcaaatatt aaaaattaaa 83160 gatatcatta gtgatattga ctcagctgta gtaggtatta gtaataatat acttgcaggt 83220 atgggtgctg actatgatgg agacacattg aatattatag ctctcttctc agaagagcaa 83280 tatgatatgt taaaagtaca agatccagtc aatcaattaa tatcatataa tgatggtcta 83340 tttaatagaa cttattcact taataaagac tcacagattg cagtttattt attaaataat 83400 cctaaatcaa aagatgtaag tataaaagct agtaaataga ttttttagaa taacggtctt 83460 atcagatcgt tattcttatt aaataaatat gactggagac attgaccatg aacaaaagac 83520 aaagaaagaa attagagaag aaaaaattag aagaacaaag taacgaaaaa attatagatt 83580 tgtcaaaatt aaaagaagaa aaggatgaag ttaaaatgaa taaagaagtt aaaagagaag 83640 gatcttacaa gaaattaact aaggaacaag tacattatat tgcagaatta attgacaaag 83700 gacacggaaa cacttatatt ttaaaagaac ttaaagctaa gtttggtatt gaccgtaaat 83760 cacattcaat cacacatatt agacgtggtg aacatcctac atttaaagca cttacagatg 83820 acaattatca ctttgctgaa gtgggatatc ctacatttaa tgaatacaaa aagattttac 83880 gtggagaagt taaacctaaa agtaaaacac gtgtaaaaac tgaagaaacg gttaataaag 83940 taaaagaatc accagtagta gaaaaagtat ctagtgttac agaagaaaaa gtagaacaag 84000 taaaagaaaa aatgagtaat attcaaaaag ataaagaaac tggtaaagaa tatcgtgata 84060 aagaaagtat tcataaagca ggtaaacctc aagaaactat ctttgataag attatcaaac 84120 gtgttttaaa tattttataa tagaaaagat gataagaaat gtccaaatat gatttaactt 84180 tatatcatca tttaaaacaa gaagtaaaac catgtagatt aacaacttca caggatgaga 84240 caatgatacg ttgtccgttc tgtggagatt ctaaaaagtc taaaagttca acacatttat 84300 atatacaaaa tagaactcca tttaaatatt tctgtcaaag atgtaatgct tctggagtta 84360 tgagtaataa agttttagct atgttaaata gtggtaatgt agaaataaat agttatatta 84420 acaatcaata taatgaatat atttctaata tgaataaaaa atatggcaaa tcttttatca 84480 atagaaatac aaaagaatta aaatactacc caaataaata taccgattta gaaataagaa 84540 agattaatta tattaatgaa agattgggta ttaacataga tgagaaggat attgaattat 84600 ataagattat tttaaatata gaagattttt ataagaataa tgaatttgat atagataatc 84660 aatatcaaat aaataatctt aataataatt attttagtta tatgttgaac gataagaata 84720 ctattaattg taggttaatg aatagtaata catttggggc taatgggaag aaacatttta 84780 aacaaaaaat atttaagaac ttagctgatg aaagtactag attctattca attaaaaatg 84840 aattaagatt ggatagaaga gtatataaca ttcatatagc tgaagggttc tttgatatat 84900 tggggatatt taatcatgtg tataataaag aaataaatga caatgatata tttatagcta 84960 ataacggaaa aggttataaa tttgtattaa attatctaaa tagtttaggt atacttaata 85020 tgaatataaa tatttattcc gatagagatg ttaaaattac tgattatcgc agtaagagaa 85080 tgctcggtaa ttcgctacca gtaattttaa atgatgctaa tatatattat aatgaatttg 85140 aagatgagaa agattttggg gtaacaaaag ataaaataaa attatcagaa ccaattaagt 85200 ttaatcaata aataaattta tattataaaa gtgaggtaat ggatattata ttcattacct 85260 ctaatattat ttacactagg agagtgaatt ggatatggca aaagaaattt ttagttcaga 85320 agatattttt aaggatttaa cagattttca cacagaaagt agattagagg aatttagtca 85380 caagaatatt ttaacgtctt tattagaaaa tgcagatagt aaaaataatt tagaaaaaat 85440 aatattgatt ctatctataa atattaattc atctttaaaa aatttaaatt ctattgaaga 85500 tgaaatgata gatgttttta gtaaagaaat agatattaag aaagataaag ataatattga 85560 tttgctatta aaaaatctta gaaatgttaa agataattca agtatggaag acattaaaga 85620 atatttagta ttagaagtat ctttagatga ggttattgat aaaattaatg aagatgattt 85680 ttataatgaa gaagtaaaag atttatatct taaattctat aataatcttt ctattttaat 85740 tatatctttt aaattgttaa cattctataa tggttttaat aatgtagtat cttaattaaa 85800 tttaatataa ggagaatgat tagaatgaga gataaatttt tattatttga aaatgatgat 85860 aatagcatat atatgctatt atcaaatttt aaattcaata aagaaattaa aatagattat 85920 acacatgata taaaaaatat cgatgatgtt cctaagtatt ttaataaagg aataaagaga 85980 tttaaaatga gatatgactt tcattcaggt catattatta gacaagatga attttacaac 86040 tacatggata atttagatgc tgattttaaa aattcaaatg ctaaagcttt agagaaaata 86100 actttctcta atcttattag tgatgataaa atcaatatag tatatacagg taagaaagat 86160 gataataata aaattgtaaa aactaatatt tactttattg tccctgttag tattatttct 86220 gaggaattaa attcaaatct aatatcgtta gatattacag ctatgaataa aagattaaat 86280 gatgtttata aatctgaaac aaccaatcag aaattattag ggataaaacc tagtgttaca 86340 aatatcaata ttattgatag acaaaataaa attattaatg aatactttag agatatagga 86400 gtagaatata actttattaa tgattttagt aaatcagaag aataaaggag attatattta 86460 tgattgaaga agcttttaaa ttaaatttca taagtctatt attaaatata ccttactttt 86520 taatatcaat ttacttattt tattattttt atacttacaa gaaaattaaa aataataaag 86580 atgatatata cgatgtagct ccagtggctt ttacaagtta tttgagtata ataattataa 86640 ttatactcaa attatctact aatagtttat ctcaatatgg taatttgata tatcatcctt 86700 ttaaaatatt tactttaatt atagtaggtt taataatgta tgtggcacta gatgcttcat 86760 tatttatatt tgataagatg aaaagttcat taaaaatatt cattgtattg aatatctttt 86820 taatttcatt attaatatct gattcattat tatttaatat gattattatg atagtcatat 86880 caattctatt aattttaacc tcattatact ttacagttga tcatttagat agtaaagata 86940 aatatgtaaa aataactttt tgcacattct ttactttatt ccctctattt ttatcattgt 87000 taattataaa tatggatgta attaaattta acttaataga tgttaatact aataataaaa 87060 ttgataatat gcatttaatt ataattgtac aaataatttt actagtatgg aatttagtag 87120 taatgatatt caaaatattt aatatcaata tatacaccgt tatatcagaa ttatttaaaa 87180 gaaataaatg aatattagga taatgatcaa attaatggtc attatcctaa tatcattttc 87240 tttttttgta actaccatta ttttagatat atattataat tatgaaggga ggaatatagt 87300 aatgatattt aatattctaa tagcattagc atatgtggca cttgtttctt taggattagg 87360 tgtttcagct ttttatatat ctttattttt attaagatat ataaaaaata atattatcaa 87420 gaaagaaatt aaaaatgaaa atagaaagtt attttatctt tcgttattaa tagttataat 87480 attcatgtca ataaaatcat acgttgatat aaaattaagt attatagaac aaatattaaa 87540 aatgtagaaa agcgtaacat aagacatttt aattatatat tataataatg aagatattat 87600 aatattaatt atatctttaa taaaaaaaaa gaggagaaat taaaatgaca gaatttgaaa 87660 atgaaactaa agtatcaaaa gaggagaaga agattaaaag atttattgat caaggtattg 87720 ataatttatc tgatacagta ggagaaggta ttgaaggtat tccgttatct ttaactgatt 87780 attttcctaa aataaagaaa ttaattatta aattaattga tagagaggaa agtgatgaaa 87840 ttaaaatgac gaatgaatca ggtgaagtat ttaaatttaa tagaacttca catgatattt 87900 atttaacagc aatcaaattt taaagaaaat tttctatgat ccaaaaaaaa aaattaaagg 87960 tgtggtgtat atgattaaag tcaatgaact attaacacaa gttaaagaaa taaaaacaaa 88020 tgacagttat acgaaattag taaacgagta tagagatatt atcaatgaag aatatatatc 88080 ttataaacca ttaaaagatt attacaattt cattatatat tatttagaaa aatctagata 88140 tcaagcattg aaatctaaca attttgatga atctaattta aatatcaaaa cattgataga 88200 cgatctaatg acattaaaca atattgttaa atctgatatt tttgatacta aagaagtaat 88260 cagatctact ggttttaaat taacaaatgg tagtacattt gatagaatta ttaaatacat 88320 taaagataaa ctagataaat taattataga gataaattca gataattata aatatcaaaa 88380 tatctatttc tatctacctg agctaaataa tctattgcat aatacaattc atatagaacg 88440 tgttttagat aaaaataaag ataatgtaga tattattaat atagataaat ataatttatt 88500 tgaaatgatg ccttgtaatg atattatgga taaagatgaa ttttatataa tggttaatca 88560 tttatatgat ttaggatctt tagaaaaagc gtaacgtgta ataaaataag tatatattat 88620 aattatgaag aaagagttta tcattaattc tttctaatat aaaattaaat ggaggaattt 88680 attatgaaaa agaatttagt attgaaaagt gtagcaggtc ttggattagg tattgtatta 88740 ggtgtagtaa gtaataagat tgacgacatg attatgcaaa aggaaatgga aagacaaatt 88800 tttgaaaaag cttcagaaat gacttttgaa catccgttcg ctaatttaaa ataaaggagg 88860 aaagaggata attgttttaa aggtctaatg aaaatggatc aagttcatta ggtctataat 88920 tttctatgat ccaataataa aaaggagtta aaaacaatga ataacaaaac taaattagca 88980 gaattaagaa aagaattaaa aatcgtatat tcggatatag gattgagcaa aacgagtact 89040 gtagaagaaa gacttcacaa gaaaaaagaa agattaatta aagaaattaa tgaaatagta 89100 gaaaaagatc aaaacatttt tgatagagaa aaacatatag caaaagttaa agaccgaaat 89160 aatgataata tttacaaagg ttcagatgaa ttttctaagg caggtagact tcatagaaaa 89220 tatcaaaaac aagataaaaa cagaatattc aataatccgg tacaagatta aatattcata 89280 taatcagttg aatttgaaaa agcgtaacaa tatggttttt aattatatat tataattatg 89340 aagaaagagt ttatcattaa ctctttctaa taaaaattaa aggagaaaaa ttattatgaa 89400 aaacttagta ttgaaatcag cagttggatt tgcggcaggt attgtattag gattagtgag 89460 caataaaatt gatgcgtaca cattagcaaa aattgaagag aaagaagtat tagataaagc 89520 agatagtatt attaataatt aattaggagt tgaaaaggat aattgattta aagacctaat 89580 ggacacggat caagttcatt aggtctataa ttttctatga tccaataata aaaataaaaa 89640 tgaaaagagg aaattaaaat gttagactta ttaaaaggaa ttgaatttgt aaatgaaaag 89700 gaaattaacg aagagaaaga attattaatc aattattcag atgaagcaag atatccatct 89760 gaacaagctt atagagaaat agattcaatc atcgaaagtt tcgacaatac agctttcgga 89820 ttaagaaaat ggggagtgta attagaatgg ttagagaaga aaaaatcaaa caaatgaaac 89880 aagaattaca aaaaatatta gataaagaaa ttagatttgg ttataaacca atttctaata 89940 gagactttga aaagaaatta aaattaatga aacagataga caagttaaaa tttgacatta 90000 gatctgaaag atatttaaga aatgtcaaaa agaacaaaat aaaggagtat aaaggtatta 90060 gcgattatgc aaaagctgga agattacatc aatctttcca aagtaaagaa gagcataatc 90120 tatggaaaga agaattagta attcaataac ataaatggag gaatttatta tgaaaatttt 90180 aagattaaaa actgaatggg cgttagtttt aggtatgata ttaggttcaa ctattggttt 90240 aatgtcaaat gatttctttg taggagctac aatttctatg ttgacaccaa taattactat 90300 agcaattaat tatgtaattg gtgatgaaag aaaatctaaa atccaagaaa gtaataaatt 90360 atactatatt agaatgaata gtgaaaaagg agatatattt aaataatgaa taaagaaaaa 90420 agattattga aactaaagcc atggatatta ttttggttta ctcttataac tggttttatc 90480 ataggagaaa tgattggata cgtagaaggg aaatcgttat ttttaggttt aattttgtct 90540 ggaatatgtc tatctatcaa ttatgttata ggtgaaatta gaagagatgg attaagaagt 90600 gattaggatt aaatttagat tattaattaa ataataagga ggtgcttgga tatgttatta 90660 gaaaactttg ttacaattat cgtgttactt ggtttaatga aatttacagg ttgttttaaa 90720 tttatgaaag aaatctggtc taacaaaggt aacaaataac aacaaaagag tggattattt 90780 ctatgatccg ctctacatat ttaaattaaa aaaaaaaacg aaaagaggaa attaaaatga 90840 aaaaattatt aatggtgtta gcattaatcg ctttaatcgc agttatcgga gcagcaggaa 90900 tatttggtta tagtagtttt aaaagcttaa cagtcaataa agaagatagt aagactgaag 90960 aagtatctaa aaagaaagaa gacaaaaaag aaaagaaaga acaagaagaa tcagataatg 91020 tagaagtaaa tcaacaacaa gatcaaactc aagaagtaaa taataatgaa cgacaaaatc 91080 aaactacaga agatagtaat acaaatgtac aacaaaatca acaacaagaa ccagtagttg 91140 aagagaaaac tcaagtaaca gataatgaag gtaataatat agatgatatg gattcagaag 91200 aatttatttc taaatataca gaaggaatgg atgaagaaga agctcaaaca gtaaaagaca 91260 tggctgaaga agattcagga tatgaagatt tcttacgtgg acaagtagaa gctagacaaa 91320 acggacaagg cggaaattac tgataagaag aaaagagtga aatgaaatga aaaaaatctt 91380 aagtatttta acagcgatag ctttaatcac agttattgga gcagcaggag tattcggcta 91440 tagtagtttt aaagaattaa ataatagtaa agatagtcat aaagttgaaa caagtaaaaa 91500 acaaaaagaa tcagatgata aaaataacac tcaacaacaa gaacaaaata catcaaaaga 91560 aaacaacaat atccaacaac aatcaaatga agatagccta acagaaaata tggatgaaga 91620 atataaaaaa caacaggaaa tgtatgaaaa gcaatcaaaa ggtgaagctc cagaaccggg 91680 ttctataatt ggcaacccac caaaaaatta tgaaactcca gaaaaagata aaataactat 91740 aagtgagtta agagaagttt taggcgatga tattgatgaa agtaaaattg atgaagcaaa 91800 agcgtctggc gaatatatta atgatgaaga ataaaaaata aataaaaaga atagaggaaa 91860 ataaaatgaa aaaattatta gtagcattat caatcttagc agtaattgta gtattagcag 91920 cggcaggtgt gtttggatat tcaaaatata aagaagcaga aatgaaacaa cataatttag 91980 aaacacaatt agaagaaaaa aattccaatg agcaaactaa tgaaaacgat caacaacaag 92040 aacaatcaaa tacaaatgaa tctcaaaatc aagaaaatag ttcaacaaaa gacaataacg 92100 acaataaaca aaaagtatct agggacaatg tatttgacta tgctttagct gcagtaaatg 92160 aagtaggtga cgctgattta atgaaattcc aagaaccttc ttacagtgat ggtgtatgga 92220 caattgacgc taataataaa tctggttcag ggtctaatac tataaaagta tacgatgatg 92280 gctgggtaca gatatatgat ggatctggtg aaatagctca tgaaacaaaa atagaactat 92340 aattattaag gagagttagt gatatgatca aatcaataac aaaagaagaa ttagcttttg 92400 ataaatttat ttcagattta gatttaacta acgtgtatga tagctttatt attaatctac 92460 cttctggacc taaatttatc agattaaacg aatttgatga aattgaagta tatgagaagt 92520 atgattcaaa tttaattaaa atagtagata tagatggtga atatgatgat tcattttcac 92580 tattctttaa aatcacaaaa ggaatttaaa atattatagt catgaatcta tttaagtagg 92640 ttcatgacta ttaattatat atttttttat aaatataaga aagagagatg acattaattg 92700 tgtatgaaat ttcagtagct ctaatgtttt taattataat atatttttca ttcaatacaa 92760 tatataaaac attagtaagt gcgtataatg aaaaattaaa aggaaaattc ttctctacat 92820 catttttcat ttttagttta ttgtttccaa taatgattat tgtattttac aatatagacg 92880 ggataaatat taaaatagaa tatgttttat tttattttat actattaata attaactttg 92940 tattaaataa atttcttaaa gttcatgata ttatagtata tacatcatta ttctattctt 93000 tatttataat gaattatcat tatgaaatag ctaatgattt atattttgct atatttattg 93060 taataatcaa tttaataatt ccattaatta aaattgaatt acaattagta gaaataataa 93120 ttcaaactgg tggagaatat aaagatatag acatgaaaaa gaatatagtt agacagaatt 93180 taaaaatagt taatttaaat gataacaata caaaattttc attagatgat tttcttgaaa 93240 ataaatttaa taataatgaa gaatcaataa atactttctt agatgaaatg attgaaaaaa 93300 tatattctga aagaataaat ataaaattgt attgttatca tatattaatg ggattattaa 93360 ctatatactt tttattatct cagatttaaa tatatattat aaaaatgagt aatattaatt 93420 aatattactc aaaaaaaaaa ataaaggagt tttatcatgg aaaataatta ttatgcagtt 93480 gcacagttcc agaatcaaag agagttcaaa ggaagagagt atatttataa agtaccagaa 93540 tatttattag aaaaagagaa ttcttatttc agtaaatacg cattggtttc taatttaaat 93600 ttaaatgaag ttaatttaaa tgatactgga gttcataacg atgatttaga aaaatttgca 93660 agttcagtta aagttgttaa agtattaaaa attatggatg aagaagaatt tatacaatca 93720 gaatatgtaa actctgtaaa agatttagat caaagaatta atcaagaagg agaaactttt 93780 gaatataaaa atatcgtatc gttctttgat aatgaattaa taacacacat tgattttatt 93840 tctaaagata acaaaaaaga aaaattagaa aaattaatga gaatcagaat ggagaaatta 93900 aataaagaaa agaacttaca agaaagaata attcaatatc aagataatga attagacgaa 93960 ttatttaaaa aatataaaga attataaata taatatccca atgagatgaa ttattctcat 94020 tgggattatt ttaattaaat taatgggagt tgaaatggat atgtttgaga caatattttt 94080 attttcttta ttattgattg cttttataat aggctttatt ggaaagaaaa aagagtcaat 94140 agcaatgtta ttattagcta tgataatcgc aattggagaa gtcatattaa caatcatatt 94200 tttatcaata taataaatag ggagctgaaa cggatatgtt aaaaaataaa gaatttgaaa 94260 ttaaccaaga tattattaat aatgaattac taaaaacaaa atacttagaa atggagatta 94320 caaaaatgtt taaaaatgac ttattattaa atttaagata tctaaaagat aatctattat 94380 catcatggtt atttgatatg agtgtagcac attttactaa tttagaggtt ttctatgatc 94440 ctgactataa aattaaaatg acttttatag tagatgataa aaatatcgaa tatactttaa 94500 atgaagcagt tcaagaaatg atttataatt tcatgattaa aaaatcaaat gatgaaagag 94560 catgtgagat tattaaatct attattgaat ttgaatattt taaaaagatg aataaaaagg 94620 gtcatgatat tgatatggag tatgctaatt tacttatgga taaagttaaa gaattacaag 94680 ataaatacaa tattagtaat aaacaagcta agaaattata tattgcttat taaaggagat 94740 agttatatct ggaagaaaag agaagtgata aattatgaaa aataataaac cgagtttaat 94800 tacatggtta ttatattatt gtgacaatga ttcaattaat aacgctatta attctatatg 94860 tatatttatt atctctacat taattatatc ttatacaatt ttaattagta tgttttcaaa 94920 tttttcatta atgtcaaaat taataatatt tttaattgtg gttttgatat ctatatttgt 94980 tatcaaaata aaatatgatt attttaattt tagagacata tatgagtaca cagacttaaa 95040 tcaatgtttt aagattgaag gagaatacta ttcaaaatgg tatattaatt tatgtaatat 95100 aaaaaattat acaatgttca taccaagacg ttctaagggt agaaatcatt ggattaattc 95160 tatagagtct aatcgtcttt taacatatag agaattctta agatataaaa agaatagact 95220 taagatagaa aaagcaaatc agaatattga agaaataaat gaatttcaga agtatatgga 95280 aataaaaaat aagaaaagag aggggaacat atgaaaaata gagtaagtat atttgactgg 95340 tatctttata aaacaggtta tgatacaatg atacctttta taattaaaat aataatgatt 95400 ctcggatcaa tattattatt cttttcatta ctaggagtta gctataaatt agcattatta 95460 tctttatttg tattagttcc aataataatt tcttctataa ttataggtga aaaatatttt 95520 aattcaagaa taatggaaga gtatcaacat ttaaataaat catataagta taaaggaaaa 95580 tattattctg catggtatat aatattaaat agtaaagatc catacttcaa agagttaatg 95640 gatattatgg gaaatgacgg cactcttagt gaagaccgta atatacttta taatctagac 95700 ggactatata tgcctccatt taaaaaagga gttatagaaa gtcatgaaag gaaatataaa 95760 aatcactgga aaaataatat tgagagtaat cgtcttttga catatatcga attcttaaga 95820 tataaagaga ataaactcaa gatagaaaaa tcaaatgaaa tgattaaaga aataaaagaa 95880 tttcaagatt actataattt aaacaataaa ggagaaaata aaaatgaaca ctaaaataat 95940 cgcagcattt ccaggtacag gtaaatctta tattaaaaac aatatcacat tcttaaaaac 96000 atctgattca gattcaacta gcttttcatg gttagtaaaa gatggggaaa agattagaga 96060 tcctagattt ccaaagaatt atattcgtta tattaaagac ctttattata agaatgtgat 96120 ggattacatt tttgtatcta cacacaaaga ggttatccaa gagttgattg ataataattt 96180 agaatttgtt gtagcttatc ctaaacgttc agataaagaa atttatctaa atagatataa 96240 agaaagaggt tcagatagta aatttattga gcttcttgat aatatgtttg atagttttat 96300 agatgatata gagaatagag ttcctgaaga aaacagaatt gaacttaatc ataatgaata 96360 tttagctaac gtattagata aaatttaaat aaggagaaat taaaaatgag atactttaaa 96420 ggtatagtag caggaaaaga ctttttctta aaagcagata atgaagaaaa tgccattaag 96480 gaattagcat caaaagaaat taattctata ggatctttta caatgttaag taatgaaaaa 96540 cagaaatacc taataatttt ctttaatgaa gatgaagata aatttgttgt tggaaatgga 96600 ttagaatcat atatatcatt agacagtctt aaatctgaat tagaatctaa agatttagaa 96660 tgttattatt tagatttagg taatacagat aatatcgaga taaacggtat tataaaaaat 96720 caagaataca cattaacaga aataataatg gaaagtatta aattaactat gaatgatttt 96780 tatcaacaag ttataaattc tgtattaact gaattaactg aaaaagaata caaaaattca 96840 atagttgtta aaaattttaa ataactagga aggaataaaa atagtgagaa ataaaaaaag 96900 aagcatagat agtttgataa ataataatct agaattacca attgagatta ctgaaaatta 96960 tataaataat tttatataca aatcattaac tgctataaat aagaaaaaag aaataaaacc 97020 aaatcaaact tatataatta atcataagaa tgaattattt aataaagcag ataatttcat 97080 aaattgtatt ttagaattat taaaaggtga tgtgggtact ttaatagata aaaaagattt 97140 aaagttaaaa agaaatgtaa agaaagacaa tataagtaat tgtcttacaa tatatactat 97200 tgtagaaact ttaacttaca ataattctat aacaatgatg atggtaaaaa atgtaaataa 97260 taccaataag gaagtaactg gtgaactaat atttgatatt aatataagtg ataaattagg 97320 taaagataat tacaatgaaa atatttatat ttaattacta tttaaatata tattatataa 97380 atgaagttaa ttaaaataca ggagatgaat tggatatgtt aaacgatact aaaaaagttt 97440 tagacagaat atatgacaaa ataaatggtg atttaattgt tatttcagag tgtaaagatc 97500 tatttgataa ggaattaaat tacactttaa ctgaaggtaa tgaagaaaca acaaatcttg 97560 attatttggc agattcttta attgtagttt cttcagatat atttacttta aatgaagtac 97620 ttaatattga tgaagaaact attaataaag aattattaga agaatttaaa ttgagttata 97680 gaatgataca aaatttccat atgaaattag aattaagtag ttataaatta aaaaagatta 97740 aaacctcggt tgaataaata taggagatga ttaggaatga attatttaaa gaatgaaaaa 97800 gaggaggtct ttccagtcaa tgaagaagga atggagaata ttatattctt tcttctagac 97860 tactcacaga aaaatgatta taatacaatg aatataatta aagaaataaa tgatcacgtg 97920 atgaaaggcg aaaatataag taataaattt attaatgaaa gtacaaaaga agtgatatta 97980 acattaggta aagtaaaagg taatttaact aatgaattag ctagaagcgg atatatagtt 98040 aatttctcta gaaataaaat atcattatcg atatatgtaa aaaataataa tttcaaatta 98100 gtaagaattt cagatcataa tattaataaa aaagtaaata agaaaggagt aattagtaat 98160 aggtttgact atcaagttaa agctgacaat aaattggtaa gtaataaatc tttaaagaaa 98220 tatggtattg atgtatcaga aggaatttat tatttagatt aataagagta ttgaattaga 98280 aatcaattat atattataat aatgaagata aatattatta atattatctt caataaaaaa 98340 aaaaggagtt ttatattatg acaaaattaa atgaagaagt attaagagat tttcaagtaa 98400 gaactgagat tgatggagaa tttgaagtca tggagtctga tgagcttggt gttgatgaag 98460 cttatgataa tgaactaatt aaagaattag gattggatga agattcaagc gtgttttctt 98520 atgcaatagc agaaaaaaat gatgaagaaa atatgtatac tttagaatat agtcatgaag 98580 gagttctact aactattcat gattatgatg aggaatatgt tcctcaagct atttataaaa 98640 atgtaattta atgatttaag tatagctgat atctttaacg gatatcagct atattatttt 98700 aattttttta cttgaaggag atgaaaagga taatatgaat tattttgaat tggaatttac 98760 aggtttaatt gataacaatc aattagataa tggagtttta cacaaacaag aaaatgaaga 98820 aattgaatcc ggtcttttaa atatgattct atttaaattg tatctaaaag aattctataa 98880 tgataatatg gatgatagtg atttatgtaa aaaactaaaa atagaaataa gaagtgttca 98940 tagctatagt gattcagaaa tttatattaa tgaggacttt gctgaaatat atgatggtat 99000 taatccgaat aataacgtta aatcaagaaa aataaataaa aattatgaat atttatttaa 99060 atttattaag gataatataa atgagaaaga tttaagtaat atacacgtaa ttaaatttac 99120 aacatttgaa atagaacggt ataagtctgt tgtacgttct atatactcag ctaaacttaa 99180 aattaaaact agtaaattca ttagtcgtta tagaacaaca aaagagttag tattctatga 99240 tatttcaagc gaaagtttat atagattgtt gaaaaataca aatagaataa gaaatataac 99300 ggaaaaggaa tataaaaaag aattagttaa aaggagtttc ttataatgta tgaagttaat 99360 aaaaaattta aatatgctaa aagagataaa gaattcacat tatttcacca taaatcaaaa 99420 gaagaaataa ctgattcatt tataattaat aattatattt catatgtatt atatcaatgc 99480 tacgaaagaa caccaggaaa tgcagaagtt tggttggaaa ttaatgacat aaataatata 99540 aaaggtgatt tcttatttaa atttatgttt gacaacagac cttcttttgg ttctaattat 99600 tttcctaagt gtaaattaaa tatacaagat aacagtgata ataatattgt aactattgaa 99660 tttagtgata aatataaaag acataatttt attctagaag aaatatctaa atttaataat 99720 gttcatatta atttttatga agaagtatta tttactaatg aagatgaaga attcaagtta 99780 ttaaagaatg tatttaaaac tgataacatt aaatattacc aaaataaaga tttaattagt 99840 tatatttcag acaaagaagc tagaaaaatt ttagtaaaag aaaactttaa atagaatagg 99900 ggcaaataaa ttgaataaat attttaaatt taaattaaat aataaaagtg attacgatgt 99960 atttaaattt tcaggaaatg aagaagaaat aagcgattct aaaattatag aatcttattt 100020 tgcttatatg tttgattatt atataagtga agcaatacct gatactagca tgataaatat 100080 tacggtattt actaaagatg aaagaaaaag attatttaga ttttctatag ataaacctcc 100140 agtttatata gaagagcctt ttagtacttt atttatgatt gaaaatgatg aagataaaca 100200 agtcaatttt agagatttta atgaaattaa aaagtttata cttcaaaaga ttatggaatt 100260 aaatgaagac gaattttata tttacattga ttataacttt gatttttctt ataaaataga 100320 ttacgatgat gtatttgata aaatattatt tactaaaaat aatctaaatc tttatttatt 100380 ctttattaaa gaaacagatg aaaatgaata taaaaattat ctagtaagag agaattttaa 100440 ataagaaagt gagatagata aatggaatat attatgatga atgaattatt aacaaaaaat 100500 gattcatctg aattaaaact aaatatggtt aaaccatata aagaagaaga ctttttcaat 100560 ttctttttaa actttattat agaatataat tcatatcata taggaaatta taaatacttt 100620 tatagtataa actcattatc ggattataat tcagattatc aaataaatgg aaatccttat 100680 gtgccatttg aggaaggaat aaaagtaaat gaagtcattc atatttataa aaataaatta 100740 tttagaaata taagtaaaga cattgaaaat agaataacct tactttatgt agaagacaaa 100800 gaagatgata tttcctatta tatattaata tctaattact ttaataggaa atttaaaaaa 100860 gaatataaag aagaacttcc cgaaaaagaa aaagtattat ctagacttat agtaggatct 100920 tttctaaatg aaaagatttt attagattca cattcagaat ttttagttat taaagataaa 100980 gaaaaattaa gcaatttaat tactaattta ataaaaaatc aaaaatacaa aattttaaac 101040 tttgatttct taagcaatag tgaattaaaa tataatagga tactatttaa taaaaatgta 101100 tatgataata aattagtctt gaaatattta aaaggaataa gttacaaaga cattattgat 101160 aaagataaag aaaaaattac gtttataaat gaaaaagaat ataaaaaact agcagtgaaa 101220 gaatcattta aataaataat aaataatctc atccattcat tatataataa cttttaatta 101280 tataataatt tttagaatgg atgagatgct tttatgagta attatttata tcgttttaac 101340 aaagagaatg taaatatctt ctatcataaa aggactaata atggtcataa aatgttattt 101400 aataatagta atgataaaga tagatctata tacttaataa atactgatga agaaatcaat 101460 aatatggaac tagtatctaa atatattgct ggaaaagtat ttgaaatact aaatcaagaa 101520 aatatgaaaa tagtacatat ggatttcttt aatagtaaat tagaattctt tataagtaga 101580 tcatccaaga ataaatatat aatgaatatg tattttagtt taaaaagtta taatgatcta 101640 attgaaaatg aaaaagaatt tatagatagt gttaatgaac ttaatttaga ctttttaaaa 101700 tcagtttctt tagatcaaga caataatcat gtattagata tgacattaat atttttaata 101760 gataaaaata agatagatga atttattaaa aatctatttt acattaatta tataaagata 101820 atagaattta taatagatac tatatctgta tatgcagatg attataagaa atttaatgaa 101880 gaaataaata ttcttttgga tcatagaaat tttatagaag agataacata taaagaatat 101940 aaaaagataa tgacaaaaga gatgtttatt taaggagaaa ttaactatga aggtttcagc 102000 caataaagaa ttattaggaa ataaagttat acctttaggg tttaaacaac ttaatgactt 102060 gtataaagat catgattatg tatatttaag aattcctgaa atatttaatg tatttgataa 102120 gtatcaattt aaagatgata aatttgtata tattaaaaca gaaataaaaa ccagtactat 102180 tgtagattta atagattctt tatcaggtgg tcataattgg ttagtaaatg aatatatttc 102240 taatgatata ctaaatatac attataaaaa gaaaaattta ttagatattt ctaacagtga 102300 atataaaagt ctagaggaaa caagatctca actagattta gaattggaat tcataagtag 102360 taatgaaaaa caaagaaagc aatctaatat tttaataaag gatattcata aagaaataaa 102420 ttatataagg aatgaataca caaaagtatt cactcttaag aaaagtaaaa ccagaaataa 102480 taaaccaata aaaataaaaa ttagaaattt atatgatgaa gatccaatat ctatattaaa 102540 aataatatta gacttaggag aagaatattg tatgaatagt actatattta acgcattcac 102600 ttattcatta atgttaacaa ataatttaga tttcatagac gaaaaagaat ttcaggatat 102660 agttaagaaa gagaaagtga aaaatacttt catttaaaac attattcata tagtttgagg 102720 aaattttcct taagctatat gaattatttt attttttttc taaaaatata aactaattta 102780 tattaataat ttttataatg tatcattcac ttagtcgcaa atatttattt attttaagaa 102840 cataaatttt atatcaaata atatagaatt tttaaaaagg agaatttaat tttatggaaa 102900 aatatgataa attaactgaa gaattagaag ctttatatga gcaatctcaa gaagaagctc 102960 tagaagaaca attcgaaagc attattgaat cagctgatga agataaagca gaagatgaag 103020 ttaaagataa agattctaaa gaggattcag acgaagaaga aacatctgtt gaagaacaat 103080 ttaacagtat cttagaatca gaagatgaag aatcagaaga tgaagaatct gacgaggaag 103140 atgaagaaga ttcagttgaa gaatccgaag acgaagaaga tgatgaagat tcagttgaag 103200 aatctgatga cgaagacgaa gaagatgatg aagattcttt agaagaagaa ttaaatcgtt 103260 tatttgaaga aaatgaagat ccagaaatgg atgttgaaaa gcaaactaca aaagctaaca 103320 acatgaactc aaaaaaatca tctgattcta ctgaacatcc tgaagaagat gtaagcaaaa 103380 tcacttcaga agatgaagac gaagaagaag atgacgaaga tgaatcatta gaagaatcat 103440 tagatcgtat ctttggttaa ttattaatta atctttaaaa tatcccctaa ccttattaat 103500 ttaaggttag gggattaata ctgcattttt ttatctaaaa tagtttgtat tatcagtcat 103560 ttttcttcca aaagcatcta atccatctaa tggattagct ttatctccag ttgctttaaa 103620 atcatctcca ccgtaagttc cactaaaatt agtgtctaca ccttttgata attcttcgct 103680 catcatattc atgtgtctaa ctctttcttt ctttctttgt aaatatgctt ctgcttcttc 103740 aactgacatt aatctactct catcaatagt ttcattttct tttaatttaa ccactggttt 103800 aaaaccttcc atgtatacat aaaacttatc aatttgatct tgataaatga aaggaatttt 103860 agtttttaaa tgaagagttg taggttcatc ttcatattgt agagtttcat aatcaagtat 103920 atttccttct ttatctactg ttactgctaa gtccatcata attttttctt catttttttc 103980 ttctgacaaa atattcaagt cctttccaat taaatattag tttctaccat aaatatatga 104040 gttaagaatc caagcattac ctttttgtcc tggtttaact cttgcacgaa ttgctataga 104100 tgctatagat tgtgccggaa tacccatatc tacaataatc tctttatgtt ttgtcttagt 104160 tacactagtt gatgtgtctt taggtataga tacagtttta tcaaagaata ctccattttg 104220 atcattaaat gaatcaactt taatatctat accacattgt ggagtagcat accatatacc 104280 aatgtgtaac catctagttt catgttgtcc gtataatgtc atagcacgtc taaagtagct 104340 accagtagtc ttatcactaa acataaatgc attaccaaca tttttaaatc ttggagtacc 104400 atttgacatc aaatcttgta cacctggttc tgaacgtaca taagctgtag taaatcgagg 104460 cataccgtta taaactagat atccaccatc aggacgttta atagtaatac cacccttaac 104520 ttctcccata gcatctaaca ttgtttgaac aacaatattt ttagacatta aattagtaat 104580 agccgcttct ttaatagtag ctttaccatt agaaattatt acatcaccat cattgatatc 104640 aaccattttg gattttaatt taatattatt aggatcaact tccaatgtag ataatttatc 104700 attagaagaa gatgacatag taataccatc tgctaaaata gataatgcgg aacccatttt 104760 ttctatttta gttttatcag cattgtaaga ttctttagta acacttaaag cgatattatt 104820 ttctgtttga ctaattctac tttccatatt agtaattcta gcattactat ctttaataga 104880 aggttgccaa gcagtagact tgttaccttc ttcaactttc aatccttcaa tatcaacaga 104940 cattgggaaa gttccatttt tattaataac catattaatt aatgtatcaa ctgtaaatga 105000 atcattagga ataaatacta cttctattaa cgttaaagca gaagtatcat caaacgtaat 105060 attacgtgaa tcttgacctt tagcaacact attaacaaaa gtattagtta tagttgaatt 105120 aggtatacta atatctacat tagttaatgt accagttttc ttttctaagt taaaacttaa 105180 tatgtgttca cgtctatttc taactttatc taatttaaat ttaatacctt gaccgttagc 105240 agttaaagcc gcattaagtt ctccgtattc taaataacta gttttagtta aagttacaga 105300 accaattggt gtaatattat caatactaac taagttcata ccgccaactg taattttacc 105360 agcttctgta acagcataac cattagaaat actgtcaata gctttttgaa tagcatcttt 105420 aatatttgat tgagcttcat tatatctcaa gtagttagtg ttaaattgag ctatttcttc 105480 ttgagtagct actccatcgc taatagtgtt agtaatatct tgtattaata tattatattt 105540 ttcattaaat aaatcatatt tattttttaa atctgttttt actgaattag ccatcatttt 105600 attaggataa agtgtattaa agattttatc tatctcagct ttatccttat caataacatt 105660 tttttgttta tcaatagcaa ttctttcagc attagatata atgccatctt taaaagcctc 105720 agtaaccgta tcacctaaac ctacagcgtt cttttcaata ttagttattt taccattaat 105780 agttttatta tagttttcta acatattgtc ataatcttca ggagctgctg tccagtcaga 105840 agaaacacta cctctttcaa ctttaactct agcaatatca aatgtaccac ttaaaccatt 105900 aagatcagtg tctactccaa gaagtaattt agtattattt cttccagtca gtgtttgttt 105960 atatacaaat gaatatctat gccattcttc atcaatatct aaatactttt cagcaattgg 106020 tgtagaataa ttaccagaag gatcaataaa gtaacaataa tcaagtctat taaatgtatc 106080 tgatctaaaa tcaaatgaaa tagtataagt ttcattgtat tctaatttaa atccattata 106140 gctttgagct cctacttgac cttcaattcc ttcagtatta attgtaaaat aacttttacc 106200 gttactgtct tgtccaaaag ttaaagcatt tgggtttgat gaatttaaag tatctggttt 106260 taataaccaa ttacctgaaa ctgctaaaga attttctaat aagtttttac caccaataac 106320 aataccatcc atttcagatt tagaaactgt ttgttctatt aaatctgcaa attgagatat 106380 ttgactttca aattcagtta ctttattatt aacggtatct atatcagctc tagtgactgt 106440 atcttgtaaa actctagctg tttgttctct aaatgattct aatttagtaa tactatcatt 106500 aatttcatta agagtataat cagtagctat actcttaata gattctgcag tttgttctac 106560 tttagtactt aaatattgta tagatgattc atatttatta actttagaca ttgctattga 106620 taaagattct tcattagatg aaactcttcc atttaaagaa tctagattac ctttaatatc 106680 agaatcccat ccaccttcag caatactatc aatatagtca atacttagtt tttggtattt 106740 tcttaactcc gtttttaatg tatcaagtgt aacatagtta gataaatcta aatcaatatc 106800 gtgactacca tctaaatttc ttaatttttc tactaaatta tcattttctt tatctaaaga 106860 atcaatattt gtatttaata cattaattct atttttatta tcttctgata gatttttaat 106920 gctatcttgt tcttgtaata aagaattgaa tttcgattta atagaattta tttcttcatt 106980 tatttgaaga agattctttt ctttatcttc cattattaaa tttcaccaaa ctttcatttt 107040 tatttaaata ataagttgat gttttatgat tttaattaaa cgaataatga aagattgatt 107100 gcatttgtat acggatctga taatttatat acataaatat tagtaatcat taaatctttc 107160 atctcaattt tattattttt cattaattca tctaactctg tatcttcttt aatagaatca 107220 aaaatagctg gaccaatata ttttaatact tctttgtcta atttatcagc cacatcttct 107280 tcatattctc ttaaatagat ttcgtaatca tcattacttc cctgaaaact ttgtttattt 107340 ttagcatgca aatcttcatc atctaatttg ataacaaatg ttggtttttt aacatcaatg 107400 tgtttttctg ccgcttcaga tctaaattta aagttttcag atttattaat agtatcacga 107460 ataatatcaa ctgtattctc taaatcgata tagttcataa tgttatttct aattctcatt 107520 attaactgca aatctctaat atctttttct tcattaacta atacatcttt attatttctc 107580 attgttattt attctccatt cttttctctt ttattttttc tattaatgtt ttatatctat 107640 ctaataatac tttatccatt ctacctttag attcttctag atcatctttt acatatttaa 107700 tatgtatgaa tgttttatct ttaaaatcac tagaatactt cttaagagaa gttactttaa 107760 atatctgagc atcatctttc caaaacattt cattcataac atcaaatgta gttttttgga 107820 aattatcaac atcaggagta tttgttctct taattaaacc taaaagttta aataatataa 107880 gttttattga atcagtatta ttacaaggat ttctttctgt aattaattca aattcaatag 107940 gactttcaaa attattttta atgatatctt ttataaaatc ttcttttaat tcttctttca 108000 ttcttttctt taattctttt ttatatgtgt gtaaaggatc ataagttctc attccgcttt 108060 ttctatgtct aagatattga taaacttcat gatcatctat agaaatgata atttcattat 108120 catttacact tttatactca atgttacaat ttttaacttc ttcaatttta tctaatatct 108180 ttttaggtac ttcttttttc tttttaggca ttttcattca attcctttag caaagtgtat 108240 atttataata ataacgttat atgtatatta aaatttttta taaaataaac ggtaacattc 108300 aatttaatga atgttaccgt aaagtatatt aatttgattg atctccagca gatcctccac 108360 ctaagatttc aggattataa ttagcatcag ctataacatc tgattctatt aattcttcgt 108420 cttcagtagg aacttgttgt tctaaatttt cactctcagg aatttctgga acctttgaca 108480 agtttgtagt ttcttggttg ttctcttgct ccaaaaaagg cttcactgga ggaagaaccg 108540 taccgtcata gtccattgct tgaagagatt tttcattatt tgtagtaggt ctacttttaa 108600 ctaagttacg ttcagagtcg gctattcctt cagtagtact atctacaaaa cgaccaacta 108660 aactagatat aacacctgct aaaacttgaa ctatacttaa aacattagtt tcagtgtcac 108720 cagaaacttc tccaccgaaa gcacgaatta agaaaataac tacgttgact aattgaatta 108780 ataaagctgc cgtccatgct ttatttttaa atctaactaa tacgttaatg tgtttatctg 108840 caccaatttt taaatttttt gccaatttaa tatttctcct ttttattaaa ataaatattt 108900 aaaactatcc tccaaatatt cttctaagta tatctaagat tactgaagga gctagtatca 108960 aagacactat attgataaat aaatttcttt taaaagtttt actttccttt tcatcactat 109020 tagaaccgtc ttcaatcttt ttaaactcaa tttcaaagtc ttctatatta agtttactat 109080 ctaaacccaa tcttaaatct tgtatatcgc tagttatctt tctttcaact tgttcaacat 109140 tttgatttaa ttcttgttta acagattgta tttgtgattc taattcataa tgtcttcttt 109200 ttctttcttc ttcttcaatt tttctatttt ctctatcttc tttcatttct tttctaattt 109260 cttcagtatt tttacccatg ctttcaagta atacttctac acgtactaag gtgttacttg 109320 ttttttgact ctcagattta acttcatcta ttttcttatc aaacttctct tcaatttctt 109380 ctttaagtga attatttgac tttagtaatt ctaattcagt tatagattta ctattttcat 109440 acaatcttct tttatcttct tccatttata atagattcca ttctcatttc aagaattgta 109500 aatactgcaa agaagagatt taggaaagag atgaaaattt ttaatattat ggtagattgc 109560 ataccagcac tatctaaaga taaaatagcg tatattaaaa atagagcgaa gttaataaat 109620 gcacctatag tcattaaagg tttcgtcatg aaattatcta agaataggga agcggctaaa 109680 gccaatcctc caataattaa aaatactcca tatgttttta aatccataaa atgagaaata 109740 gccacataaa tatctgatgt tctataagct tctcttgttc gaaaaacaaa ttgaaaacca 109800 tagattaaag aataaacagc taagaaaata ggagttatat aatatttaaa ttgcttaaga 109860 aaataatata atttgatgac taaactattt gcttcttcaa cacttagatt atcttctcta 109920 tcattatttt tattatcgtc cgtcatagtt atttttcaca tcctattctt ttattataaa 109980 tctttattat aaatctttgt tcttttaata gacttgatgc gtcctataaa ttttggagca 110040 aaataaagtc cctaacactc aaataagaat gttagggact gtttgaagac tttgccaaaa 110100 ttaaaagaaa aaagaataaa gatagacaag aacaaagaaa ttgtatgaaa gatatttatg 110160 taaataactt tcatataaat atgttctatt ttctttattc aattgacgtt gataagaatt 110220 actgactagg taaagatccg ccttgagcag ttgaaggatt ttcaggatct tcttcttgag 110280 gttctacttc tgtagctcga ccaatacctt ggacttcaga atcttccaca gcttcatcaa 110340 ccatatgttc ttcttcaata ggatcgattt cttcaaccac ttcgtcatca ttatcaatga 110400 tacttgaagt agtatactga ggactttctt gttcttcagt tgtattgtcg tttaattcat 110460 ctaagatttc tccgactaat aatcttaaat tattaccttc ggaaacttct tctaattcta 110520 ttacaccttt agcaactaaa gttgcatgaa aagttacaat aaaagatttt ttatcaattt 110580 tcataattta aatttcctcc tattttttat tagccaataa agcagctaat ctctcttgaa 110640 gctcacgaat ttctttttct tcaggagttt ctactggttc ttctttctta ttgaaagttt 110700 gaccaggttt ttcggctaat ctaggtgtag cattttcata ttcgattttt aatttttcca 110760 tctgttcacg aatattatgg tctacaataa atattaaagt ttcttgagtt gaatcgttca 110820 tattacctat agaataacct gaaaagtttc cttcttcatc tatatcttgc atattgataa 110880 tcaaccaaaa taatccgtca attcttcttc ctctatcatc atacatactt ttatatgttt 110940 ctacaagtgc cattataaat cctcctataa attatatttg ataattcata gtttattttt 111000 ctattacgta atcgccacct tcaaaatcac ttaaagacat acgaagtatt tgaagctggc 111060 catagttaaa ccctccagaa gttcctgtta ttgctagctg tattacaaat gttttactat 111120 aattatcagg tttccctaaa tctatggtag ctatctgtat ttttagaggt tctccacctt 111180 taactgctat ctctttaaac ataggaattg atgagttagt cttccaacct tctttttctg 111240 caaaagttat ataaagatta ttaccttctg tggctcttcc caggtaaaca aattttaaat 111300 aacgtttatt atgatgataa ctaaatagat taagtgtagc cttgtctttt ccatttgact 111360 ctgctaattg agcattatca taaccgtact tatatacatc tctttttatc atatatgctc 111420 ctgcccatgt atcagtttca actatttcca tatgattttt aacatctgaa gaacctgtaa 111480 catgattcca tgttttaagt ccaggcaaag taggtacaat atttgtttca gatttaaata 111540 gaccatcaac catttgatct acaccatttt ttctaatgtt caaaccagta gaatttattt 111600 caacataatt atcgttatct aaagcagttt ttgatattct taacctatct ccagtaaaat 111660 ttaagttacc tttactatta tatatagtca tcttatcagt attaaaatca atgcttcttg 111720 atatcatttt aattgattct ggattcatag ttattttact tgataaagaa ctagtactat 111780 acttatctaa tgccgaaggt gtccatggtt ttaattggtt tcctttttct aattttggaa 111840 gagcatagta aaatacagtt ccatcattat atacatcagg tttatcatag ttattgtaac 111900 gtaataaaaa tcttagataa ttagtttgac cattagcgga acttctaggt attttagctg 111960 taaagctata cctagtccat ttatcaaaca caaaatcgct tgctggtatt tcaactacac 112020 caaatttagg attagtagtt tgttgtatat tttcatatgt tgctacttca aaatatattt 112080 tataagtaag agactttcta gcagttgaag gaatgtatat ataaacagaa cctgttactt 112140 catctccaat actaaattgc ccttcttgtc ccactggtaa ataacttgaa attactgcag 112200 gccaagttgt tccgaatgta ttctgtttgt atttaaatac atttcttact tcattgatgt 112260 tgtatgacat atcactgtcg ttagagacat ctttagattc cttgacaact atattttcaa 112320 aagaaacagt tatatcagag ttatcagtgg accctgcttt tgcagcataa aataataatt 112380 gatttatttt atcctcatta ggagtggtaa tctctattat atttctttta tttgcactga 112440 caggatagtc taatctatta accgaattaa tttcaggaag tgtatctgca tcggttgagt 112500 accctgaacc tttataagga tatctatatg gatataatga aattaatcca tcgctattct 112560 tcccagattg tatattataa tcaaatgcaa ctttatattt agtattcttt tttagataac 112620 catttaacgg aagagtcatt cttttataag gtcctctaga tacgttgttt acacgataaa 112680 ctgatcctaa agctaagtta tcatctgtat taattgtcat gtcttcttca gaagatattg 112740 agaatctagg gtttttagga taagttccct catcaagtct tatatttcta aagtaaaact 112800 taccatctga gtaaggagaa acggaagcta tgatcaatct tatttgtttc atatcactta 112860 aatctgagct agttaaagta aaattagttt ggaaagtggt ccaatcatca ttaatatcat 112920 tctcagcaga tattgtataa cttaatgggt taactgtact tgaactattt ttatttacac 112980 gaagacttac agtaatagaa cctttagtgg tttctactgt ttttctaaca tcaaaactaa 113040 aattataagt accgggctta attttagcta attttgagct tccatctgcc ccattataat 113100 caatattgga tgtctgccat tgcttccaac cttcactagc atctgaaatt atagataaat 113160 aatctctata atttgtagta gtgtccgttg gatttttttc agtagatcca ctaaaagtat 113220 aagcccaata aggtgaatca atcttatctg cgaaatttaa attctctgat gtttgatcat 113280 cattagttgt ccatccttcc catccattcc taagatcaga gttaataagt gagttatctg 113340 cattaagata tttacttatt ttattaacag atagttcaat agaatctgct ttttgatcta 113400 ttttagaaga aacagtagat attgaagtct caatatcttc aggtgctgga gaccaatcag 113460 tagatttatt acctttttct actttgatcc actctatact tgataaataa tttccatctt 113520 taggcatatc gtatactgtt aataatcttt ttaaatttct ggaagattct tttgctgttc 113580 cagttcctat ccaaagatct tttttagcat catatgttaa agtacataga tttgtataac 113640 catcatcggt ataagcactg aaataatgat ctttattatt tacattacct tttattgtaa 113700 ctgtataagt ttctccaatc acccaatcca atgacatatc atatggtttt ccatataatg 113760 tatgattggt gtatttatta tttttactat ctagaactaa atttcttcca ccgattctaa 113820 tattatcaat ttgtgaatta acatcttcag gagcaggtgt ccaatcagta gctttattac 113880 ctttttctat tttaatattt tcaatagaga atttatctcc attattatta ttgtaagcat 113940 atatagccca tctagaatta gttccagaag tcttagttat tttagaagta tatttatatc 114000 taaatttttt attaccaaca ttagttattg tatcactacc aatagacatt cctggatcta 114060 ctacactatc atatattcta aaaacatctc cacgttccat ttgtaaatca aatgatatag 114120 aaatttcatc tccgactttc actttattca ttaactcatc aatataaatt ctccataaat 114180 attgataagt accgtttgaa ttatcttcaa aacctttatt ccaagataaa ctgttttcta 114240 ataagtttct agcacctatt tgaatattat taatattttc attaactcta ttttctactg 114300 cagtaacttg tgatgtaatt tgatttggta attgttggat gctagaagta ttagcagaaa 114360 ttttaccatc catctcatct tgtttactaa caatactagt gatcttatca gtttctactt 114420 ttaattcact atactgattt gtagttttag tatctaatgt cgtaatagaa gaagcgttaa 114480 gtgtaatatc tttctcagtc tgagttatac gagtttcatt tttagcaaat ctgcttctat 114540 aatcttctgg tgatacgtcc caagaagaag ccacattacc ttcttctaat tgaatatgac 114600 ctacgtaagt gtctttagtt gtattatttg cagtgaactg aattttaagg aaattatttg 114660 ttttagaatt gaatcttaac tcatatctag taggagttgt tgtcagtgtc ttagcagatt 114720 cagtcatagt aataagataa tctttaggtg aaacttcagt agttaaactt gaagcttttg 114780 taataggtgt tttaattact ggtgaagcgg cagctgaata agcatcataa cttaacacat 114840 aatttgtatt aggtttaact gcaactattt gagacacttc agctaaattc gttttagtat 114900 tagcataagt tataccatta ttgacttttt tagtaatgct agctaagaaa ggtaaatcaa 114960 atttttcagt tccagcaagc atattcttag ttccaatttt aactttacct gaaatagctt 115020 cagtactcgt ttcagaagta actctttgat caattctacc aatttcagct gtaatattag 115080 tatttaaatt tgatacagtt tcattaacac tagttttagt agcataatct ttagagatat 115140 cttgtctaat agaatcagct gtagtagtaa tactagcctg taaagtttgt ttagtgtcat 115200 taatagcaga ctgtctatct gtaacttctt gagttatttt atcattagca acttttaatt 115260 caccagttag attactgata ttaccttcat ttttagtaac tttatcagca gtaatagtat 115320 agctatcatt aagttgagtt actttagttg ataaattaga atagttttca tcgcttctat 115380 ctattctaga aactaatgat gtgatattat cagtagctac ttttagacta ccttctagat 115440 tagtaacatt ttcttgagtt actttttgtt cttcagaaat agctttaatt tctccagcaa 115500 ctgtttctaa tctagatgat atatctctaa caactttatc atctaaatct tctatcttct 115560 tagaaacctc ttgacgaatc atatctactg tttgactgac ttcagagaaa ccttcaacta 115620 tctgtttacg ataatcatcc atttcttttt tagtcatcat agtagctact aattcgttag 115680 tatcaattac agttttctta acagattcta gtccagtaac atcatacatt tctaaattag 115740 taacccagaa tttaggctca tctgatccat cttcaaattc agtaacatct gaatcttcag 115800 attggtttac tttaaagtat aatgtcatat agaaagcacc gtataagaaa ccattagtac 115860 ctctaatatt ttctttagta attaaacctt gacggtgata ccaaccatta aattcttcag 115920 gatcgtcatc ttcttctgta ttaggaatat cttcatcttt aattaaagac cattcaacat 115980 tactatcagt gaatgttcct gaaactttag ttccagcagg aaaacctccg tcttcagaat 116040 cataattaat taaatcaaaa ggtctattta aatagataca attattttct ctatcaatag 116100 ctccaaaatc ccaaccgttc atgaatacat ttctagaata agttgattct ccataattat 116160 aaccatcatt actcttgaaa ttccaaataa ctaatgaatg attatcatta taatccacta 116220 aattaggatt aatatttcta ttaactattc ctgcattaga tacattataa ttattagtca 116280 tattcttaat agcttcttct tcatctactg gagttgaatt agtttcaact ggttcgtcag 116340 attcagtcat aggaatatca ggttctgtag ttttatcttc ttcaggagta tcatctgcat 116400 atattactct atcttcttct tcatcaggca atgcattagg atcatctata gaaagaatat 116460 catctgcatc attaggtaat ataaccgatc catctctatc ataatcataa acaggagtat 116520 catcttcttc atctaacggt gcagattgga atctgtaagt atcatcaagg ccatcaaggc 116580 tattgaaata aataacttta tctccttgtc ttaattcttg agctaattca attacaggtt 116640 tttcactacc cattacatgt tgagattcta ttaactgtcc gtctttatca taacttaaat 116700 gacctataga agaaggaaga gaattattat tcttcataaa catagaaagt ttatatgtct 116760 tctctggatt aataggtatt aatctttcag aagaaatagt agagttaaat ccttccattc 116820 taaatgaagc tgctgattgg aaggcatctg aattatcgta atacattcca gggaagtttg 116880 attcatctcc ttgatctgca ttaccattaa aaattaagtt atctccacga gaatccatgt 116940 agtaattaaa ttcttgttgt gatacttcta attcttgacc taaatcttct ctaacactat 117000 tagcttcagc catagcttta tctatatctt tagatttttg atctaactct tcttgttgtt 117060 tttctaactc tgttttagta ttctctaaat taactttgga ttcagcaatt tcatctttag 117120 ttttttgaat ctgttcttga ataaggtcaa acatatcttg tttatctata gtgccatcta 117180 ttaaaccaga ttcagaatta agcggtaaac ctaatacact tgatagattt tcttttaatt 117240 gagttaagtt ttcttttaaa cctctatcgg aatcattaag gtcactttca attctattaa 117300 ctttcactct cattaattct aaagaagttt ttacttcatt gatatcttca tttacattga 117360 tattccctgt taatttttga gttttactat cataagataa acctaaaact cttccaattt 117420 cagaaaatac agtatcttta ataccatgag aatattcatt ttgaagttta ttcatttcta 117480 agttaatagc ttcattagat aattcaataa tacttttagt gctattaact acagaataaa 117540 atcctacaaa tgatttatta atatctttca ttaatgattc attctgatca gctctattaa 117600 gtttattgac ttcagatttt attttatcaa agtcattatt aatttcttta attttatctc 117660 taacctgaat tttaattgca tcttctttaa gataagctga atcaaatata gattttaatt 117720 ggttaacaac ttgatctttt tgagatttaa ttaaattaaa atcagaaata atagcatcaa 117780 agttaagttc tttatttgat tgtaatacac ttgatccatc tgtaccacta ttgttattat 117840 tgctaatatc attaatataa tttttaaatg attctaattg tttattaact aaagattcaa 117900 ctaatttaac atcattactt ttagaagttg tactgtcttt aataaagata ttatcattag 117960 catatttagt ataattctct aacatttcag gtttataaac ttcattagaa tctttatact 118020 tagcaaagaa gttaaatttc tctatattgt aatcgaataa acttctctct aatttatata 118080 tttgaaaacc tgctgttaac tcaggtttaa tatttttata attgatgaat atttgacttg 118140 atataaattt attataatga cagttagtcc agtttcttag cactaaacca gtcattttta 118200 aatctatagc attcaaagaa ctgtcattaa ggtatttaga agcaatttct tccatttcat 118260 ctctagtttt tcctttaact tccatagtgt caaatatata attttcatct ttaataaatc 118320 tagcttgatt taatgagtct ttaacagtaa tagattcatt attgtcatta tacatgatta 118380 agccggtttt aatatttgat ttatctacat taaattcaaa accaggaatt ctaccagaaa 118440 cttctttagg attagatttt cttaaatctt tacctttatt aattattaaa gttctttcat 118500 ttgtattaat atcatactta tgtctaatag ataaatcttt ttcaaataaa atatctaata 118560 atttttcaaa tacagattta ttatttttag ataaagtaat ttcttcatca acaaccaaat 118620 cattatattc aatattatat cctgtattca ataatagagt acttaatact gattttaatt 118680 gcccttttaa ttcttcatta gaattcataa agacattatt taaatctttt acataagcag 118740 gaattaatga agattttaaa ccattttctt caatacaaac aaattcagaa tcattcttac 118800 tttcatcttt aataattata tgtgtatttt ctgaaatata gtttttactt ttgaattcaa 118860 tattaatgat ttcagttttc ttactaaaat catatactaa tttctcacta gaaattacat 118920 tttcaaaagt ttctgcaact aatttacctt caattctttt acgttcttta tctagaatac 118980 taatcaaatt taattcacca tcctttcatt taattgatat taatgtgttc catgtcaata 119040 attaatagtc ttctaattgt tcagctagag tatcgataat agtagctttt ttccctgata 119100 gttgaatttc catattatca ataatattta ataaaataga tttatctcta acagtaataa 119160 ctgctttttc ttcatcaata gccaatatat cttctttagc atttgggaat tcacttacat 119220 taagaataat actttctgga tctttagggt ctttaataat attaccattt tcatcttttt 119280 tagaaaattc atcaatcata tcttttctat ctttagcgta ttcttcataa gattctttaa 119340 gttgattaat gaatttagtt ctatgtctag atttattacc attaagtgga atattgaata 119400 acacatcata tacagtttgt aaatcttcat ttttaattgt aacttgttca attgtttcta 119460 ccatttttag aaaactcctt ttaaattgat atttataata taaattaagt tattatggca 119520 ttttaaaaaa ttactcaaca ttttatttat tatgaaacta atagaaagtg ggtagaaata 119580 tatgcctcat ttaggaaaag aaaatggtta ttccatgtgt actgcatcgc cttcattatc 119640 cagtgttata tcaggagtac aatcattcat gtggaactat tttaaatcaa tgttccctag 119700 taattttttt gcttcaactt atgtaaatac ttctcttaat tcaaattcat taaaagatat 119760 gaaggaacgt aaaaaagggt ttcctcattt atcaatgaat actcaatttg aattgggtga 119820 cggttttatg tcaggtttac ctatgtggca taagactgat agatttgtaa tgaaaaatct 119880 taaaagaaat tatagattaa tatttgaaga tgatacaaga ggaatcagaa tatatacagt 119940 tcctcaaaga tataagatag tatttaatta cggtatatta ttacaaacag aaatgggagc 120000 ttggaacgtt cttaatcaca ttaatcaaac atttgaaaat ggtggttata attatgctaa 120060 tgaaataaga ataccaacaa aattaccaga aatatttatt gttaatatat gtagaaaatt 120120 aggtttagat attaataaca ataaagatag aatgcaatta aatgattata tgatgacaaa 120180 cggtttaggt ccaattacta ataaaaaaga tttatctaca ggtaaagaaa aatacactta 120240 tgattatact actaatatat tattaaacta tcctgattta actaattacg aaaaagaagt 120300 aactaattta ataaataaat cagcttcagt tagatatgcg atatctgctg aattatgggt 120360 acctggtagt tatatattag aaattgaaga tgatttcaat attcaaagag aaattgattc 120420 actttcagat gatgttttac aattcgacat tgctatttta caagatatga ttcctaagga 120480 aaatgaaaga ggaatgaaat tattattaga aagaaacttt aatactgaaa tgaatgttaa 120540 atttgattca actcagattg aagaaatatt agataaagat gttataaatt caattaaaga 120600 acttaataag attaatgggg atattcaaaa aattgtagag ttcaaattat ttaagaataa 120660 taaacctatg agtaaagatg aatatttcgt tgattatgat acgtttgaat taattgtaaa 120720 agaacctgaa gataataagg ttcacacact tgtaatgtat gcggatacac gtaagattaa 120780 tatgataaat gaattaataa atcaaggaag aaaaaaagat ttatacaaaa tggacatatt 120840 ttagaaaaaa aaatcaaaat attagaggta actatcaaat taatgatagt tacctcaatt 120900 ttattatttt acattagttc tgtattcaag aatagttttt actaaaagca tattagcatt 120960 taattcttta gaagttcctt cagcttcttc agctttaagt ttacctactt gctctaaaga 121020 catcatttcc attggattaa tatttttagg aattttacct gaattaagtt taataacttc 121080 actagcttgc atagctttaa tagattcatt taaaaattca ttaatgactg aatctgaaaa 121140 gcttttaata actttgttat cttctttttt agtgatatca ttacctttaa ttaagtctgc 121200 tctgttataa tatacaaata aatcaatata agttactaag attatattgt atatttcttg 121260 gaaatttaaa ttagtgccca tattttcatc agtgtaattc aacattaatg caaatactct 121320 ttcactaata ttactttgtc cttctggaag aaattcatca aaatctacac ttctagacat 121380 tgataagaag tccataatat ttcttgcaaa gttttcttca ctgtttaatt cattttcatc 121440 agtaaagaat ttaataaaat cagaatatga taaaccagta atatcatctg attttcttct 121500 aatcattttc atactataaa actctctgaa tgttttacta tctccagttg aacctaatcg 121560 atcttctaag atttctaatt cttttctatt agattcttct ttcatctctt tcattaatac 121620 atttgaaaca tcctcgttaa ttctttctaa gtcattgtta aataattcaa ttgcttggtt 121680 taattcttcc attatccatt tcatctccat ttataaaaat tatttaagat tatttaatta 121740 ccattaatct catttatata atatatattt aaataatgtt tataatttta tttatatatc 121800 tgaagcttct aataattcat tatactgttc tatttgatga tctaacatgt aatctttata 121860 atacgaaaca aattcattta ctttaccaaa tattgaagat aatggaatga taattttacc 121920 tgcatgagct aattgatgat ttgttttgga tagtaatact aaacctactt tattatcgaa 121980 atgtaatttc ataactcttt ctgctatatc tattgatgta aattgttcat cttccattat 122040 agctctatta actactattt ctacaatctc atataatgta aaaggaaagt gatgatattc 122100 cattgtaacc atgtcttctg ttaaatttga cattgttata tcatttttta gattgtattc 122160 ttcttttaat attgataaat actttttata ttcatttgat cttcttacta atccttctac 122220 attcttaata aatttcttta aactattttc tgattctatt tcaaagtata aacttgatat 122280 ttgaaattta ctttttttat ttactaatgt tgtattatta tttgaatctt tcttgattaa 122340 tatattatta attctattat ttttatttag tttaacttta ctacttgaaa atttcttatt 122400 attaaatttt atatctacat ttttattact actcatttta ttcaattcct ttttattaat 122460 taaaaattaa ttaatttatt atatttatat tctttattta ttaaaaattc tttaattaaa 122520 aatatattta ttaaaaattt attaataata tttatattaa ttaaaattta ataattaaaa 122580 ataaataaac taccccctaa atcccccttc ttgtaaaaca aattccaaac tatatattaa 122640 attattagct cagaaaatta aaaattttta ctaaataata tatctgttac aaaatgtatt 122700 aatctaatac agatatatta atattaaaaa actaaaaatt tgaattaata tatttatatt 122760 taaatataaa tatattaatt ctttttataa gtataattat ataattattt caatcattgg 122820 tatgtttatt tttgaattga atagagaaca tattaagtta atatagattt ttaaattaaa 122880 aatattatag aaaatataca gagatatata acaacctttt attaaatata caaagagagc 122940 gaggattaaa tgagatataa tggctataga atttaatgat tttaatagat tcagtaaaga 123000 tgatttaaga aaatacaatc ctctctattt ttataaagca tttactgaag aagatataga 123060 aaatttagat gatgttatta aatattgtca aggtctaatt attaaagatc agtcaatggc 123120 agataaatta gaatcaaatg actcaatgat ggaatctgat ttatatataa gagctaaaga 123180 tgatacactt gatgattact attcagtttt cgatagagat agtatattaa gaacgtataa 123240 agaaaaaaat ccatactatg gtaaattaag aaatttatat gatattgatc cgtatgactc 123300 aagaacaact agtgattttc aaataataaa agcacttaat aaaactctag atagtaaaga 123360 agagtctata ttattggaaa gttatacaga gtcagtcgaa tattttaaaa aagtaactca 123420 tactagagca tttaataatc aaatatatta cagagaaatg ttttatatgt atctaattaa 123480 tgcaactcta catagatata ttaataaaac tatgtataga atattcgatg ttgatagata 123540 tacaaggaga gatcttaaaa atgcatttat atctaatggt ttggattact ttgatgagtt 123600 cccacttgaa tatcaaagaa gaacttacaa aagattaaat gatttaatta gaaataaagg 123660 cactaatgaa atatttccta taattgaaga aatattctct attaattcta ttgatattaa 123720 taaatattat ctagctaagc atccgaatga tttgaaattt tataaaacta atgtaaatga 123780 taatttcaat ccttataaaa ataaccaata tagctacaat gaaattgtcg atcttgatcc 123840 atattggaga aatactaaag aagaagttat ggataaagca tttaacgtta tacaaactaa 123900 atatttgtct actgatgctg ttatagatat aattaataac agtaaatctt tatcattctt 123960 atacagttta attaacttaa tgaaagaaga taaaaatatt atcgaagatg acagtttcaa 124020 tatgactaat acaagaatta gttctagaaa atttaatgtc tttgacggaa ttgttacact 124080 taatacactt gtcataaatt atattaaatg gaatgataac attaagaatg ataaaaatat 124140 gaatatatat gcgtataatt ttaattcaga tataaaagat actgtagatg atattcgtaa 124200 ttatatttat tctagacaat ttgataaatc agactatact gattttgcta gagagttaaa 124260 tttccttaat attaagaaat ttaaaaatag aaatacacta agttatgaag atattataaa 124320 tgaatatgaa tcatctgact tagctcaaag acaatttaaa ttcatttctg aaatgttaac 124380 tggtgaaaat ggatcaacac aattagaata ctatattgaa aatgatttaa ttattgatgg 124440 tatgagatat ttatggactc aaatatcaaa cccagaaaga aacttcttat tcaaaaatat 124500 ttcttattat gaaaacttta tgaaaatata taagaaattc ttaaatgtaa tggtaagaga 124560 tggaagaatt gatagagaag atgtatataa aataatgatt gaagacgaat caattgataa 124620 agaattaaaa gattttgtta aaattatgaa tgttagattt ttaaatgaat cttacgatag 124680 atataaagac aataagaatg ctgaaaatat tgaaaatata gttactgcag tcagaaaatc 124740 tatagactat tcaattaaga ataatcaata tacttctaaa aaacaaatat ctagatatcc 124800 tgcattaaaa tcatatattt cagatatatt agtttatgat gattctgata aagatttaat 124860 aaatatttat gatattatta atatgtataa gcataatgaa aaattccgta aagaactaga 124920 agaattaata tataatgcga atgatcctca tttaagagaa aaatttatta cattgcataa 124980 acaactattt atcaataatt ctagtaatga tgtatttaat ggatttaaga cctattcaga 125040 ttatcttaaa tttaaggaac ctgatttgta ttattatact attgtagaat cagaaatata 125100 tgatgaagat acatttgata gagaaactat ctttagagaa agaatttttg aattagttag 125160 tagtattgat aatcatttaa atttaaaaga acagtatttc actaatagta attttgtagg 125220 tatagttaat tttatcagag attatattac tattttaatt acattattta aatcttattc 125280 aactgattta atttatacta gtctattatt taaattagac gataaatttg aaaatagtat 125340 acatttaata gatgaagcca atgttaagta tagtggaact tctaaaaaag tagataagat 125400 caatacactt gacaataaaa atatcattga taaaattaat agaaaagaaa gtattgagac 125460 taaagatgaa ttaaaaatct caataattaa gaagggagat taaaaagctt gtttaatttt 125520 gatagatttt caagaagact tgttgaaagt aacgctatgg aacaagaaaa aatagatgag 125580 ataagctcaa gagtggaaac aagagactct aacgctatta atatcaaatc agattttaaa 125640 gaagatatag gaaattatat taaaggtatt gttaaatttt ctaatcctag aacaggtgaa 125700 ctaatacatc aagaagaaaa tttagtttta atgagaactc gtgtttggtt attagaaaaa 125760 ttatttggta aaggtatacc ttcaaactat aatgcagata gtactcctga tcgtacaatt 125820 tgtttattct cgattgggtc aggtggagca gatgttaaca atgcagcttt ttctccttat 125880 acagttaagt attcggatca aaaattaaat agaccaattc catttgtagt agaaaatcca 125940 gataaagaaa actctgattt aactgcaaat aatcctagta tgattgaaga attatctgat 126000 gaacagagaa gaaaatatta tcttcctgaa gataaacaag atggaaccac tagtttctat 126060 ggtaaacgtt ttactaatgc aactaaagaa aatcctcttg gagattcaaa aggatggatt 126120 attgataatg aagatggttc agtagcattt tcattaaaaa tgtcagtaga accagatgaa 126180 gctagaggtt ctatcgtaaa tgaattaggt ttatggttag ctaaatataa tgaaactgaa 126240 aataaatttg atggtactga attagctaca agacttacat ttgatagtcg ttctttaaag 126300 aacttatcag atggattaga tatagaatat attatttata tttaataaaa taaccacaac 126360 gataaattaa tatcgttgtg gtatatttat tttttatctt gttcttttat ctcttctaat 126420 aggatttcat taaaagtaga taacttatct attacttttc tttgatttct attttctttt 126480 tctatcatat taattcttat agatatatct tccaaattct taaggattaa tttagttctt 126540 acaattaatg gtagacttat caataagaaa tatattaaga ggcaaaggat aacaagctgt 126600 atcaatagcg gtttcctcca gtacttacat tatagaaaaa attttataga aaagggagcg 126660 ttgatgaaaa tactatgaat tataaagaat cgtttaaaga atttgacttc agcagagact 126720 ttgaagctgt agtcatagat aactcagatt ttgatacaaa atatgaagtt aagctatttg 126780 tttttgaact aataatgacc accttgcaag attccccaag aaatatcaaa agaaatctat 126840 atgcatcaaa tattattaac atagaagatt tagatatatc tgagaatatt gatattggaa 126900 attatttagt atgtcaaccg ttgatgaata atgatcttga taaaccttta agaaaacctg 126960 aattatatga cagagtttta cttaaattcc ataatgcaaa tcctaaattc ccatattatt 127020 acgatatgca tcttccaaga aaatataaac ctgaagaacc tcatattcct aatagaagac 127080 aaatcaaagg aaattattat agattgctta tgtatagaga agaaaacatg acaggaaatg 127140 atgttaatgt agtaggaata acattaaacg gtctaggata ttctgtcaat aaatatgata 127200 gtaaaaacta tatattcgat agaaccatgt tagaatcatt gttacaattc caaaaagata 127260 ataaccttaa acaagatgga gacgttggac caattacatt taacaaatta atagaaaaat 127320 acaatgcaat tagttattgt tagaaatgag gaattaaaaa atgtattatg aaattaaaca 127380 agatagacga agaagaagta atacctttca aacacatata ataattactc atatgaataa 127440 tttaatactt aaggaaaaca aatttagtga tagagattta cttaaaggat cttataaata 127500 ttcttggggt aaagttcaga attatctaat tagacatgct aatattagag cattacctat 127560 gcattattat gtggaattaa tagataagga ttatgctgtt atggaaggat tatccgatta 127620 taaacctagt tattaccttc aagaattagc agataaagga attatacctc agaaatataa 127680 aaatagtatt ttaatagctg tggctgatga ttttaattta tataatcctg atgtgaggat 127740 gtttaaacat ctagcagata aattattagt gcctttatgt aaaagacatc gattaagttt 127800 tcatgagata aaattattag atgaaattta tagagatgac tatcttgatc atcttgatga 127860 aaatcgtttt gaaactaaat ctatgaatag atttgataaa cagagattaa aaaatcaatt 127920 taatatctat aatgtaatga aataaaattt atttatattt tgttactaac aatataaata 127980 tagaaattta gatttctata tcgttttacc ttttgttttg tcttatgttt gtgctctgat 128040 ttcaaagtca ttttgctctt aacttcgtat agtataaaac tttgctattt ataatttttt 128100 tagctaagtt aataaagctt ataagcttta ttggacaaac tgccatgtca aatttataaa 128160 taacttacaa tatattagcg tattaagttt ttataataaa aaaattattg ctttcgctta 128220 atgattaaat ttctatttta atctttattt atgatttact ccttatataa ataaaaaata 128280 aatccccaat accatagaaa aatggtattg gggtatttta ttaaccgaaa tataatttct 128340 ttctgttact attaaatata gaataatttt ccatcttttc tactaactct ctacgtttat 128400 ctcttgcttc acgtaaatca tccatattaa gatttaattc tccaaaagta gtttgtaagt 128460 tctggaatct acttctcata gcatataatg atatttgaac atcataagaa gctaattcta 128520 agaaatagtc atgcatatta tttggtacag aaccgaaatg tttatcatga taagtattca 128580 gaacgattag taaattaaca gaaccaatta cagcagaact taatatttct attttattag 128640 gatgatgata tctaaaagta gatggtgata aattaattgc cattaaatca gacatcattt 128700 gactatctat aggatttccc atagcaaatc ctgcataagg actcatattg cctgcatatc 128760 cagttaaatt agtaacagga ttattagctc caattactct attaatatta actataggat 128820 tctcagaatc tatatagaac atattagtag ttccttctac tttatcttct ggttttataa 128880 ttactctttc ttgcttagga tgaaatttac taaatgtagg aatagtgaat ctttctactg 128940 ttttaataat ttcatcaggt tttaattcta gatcagtgaa catgaaacct acatcacgtt 129000 caatatagtt aagtatttct gtattggtta acataacctt taatcacatc catacatatt 129060 atttgaagtt tctatagaaa tcatcaagtc cattaagaac agattcttct aagaaaactt 129120 taatagtttt attactttct ctaattgaag ctaattgaga acctttatca taactgatat 129180 tagattcatc aactccagca aatcccatat cttctgcaat gtattttaca ttatctgaat 129240 tttctttaat ataagttaaa acttctctag gagagaattc agtaatttta ccattagcaa 129300 acatatcaat tgattcattt accatttgta aatcattagg attatagtta ttatgacctt 129360 ctgaaataat attttgaata taagaatctt gatgagatgg aattactacc caatcataac 129420 aaattaatct taaaggctta gtaacttcaa cttcaccaga aggtgttcta ttaattttac 129480 tgaaaccacg cattgagaaa gatacgtcag atttttgtcc aattaatcct ttcatatctt 129540 taccagctgc agtttgagct gtttctactt ctcccattaa tttattacca ttccaccaag 129600 ttctagtaac aatatgagaa atattgcgtt gatcaatata catttgacgt ttaggttcat 129660 cacttaaggg atggccactc tcaccataaa aagttcttct tgctaatttt tcttgtatta 129720 ctggactatc taaaccactt tgaataacat ctttacgata aacacgacca ttacggtttt 129780 gtctatccgc ttcttgtaac tcagcaatga atctaaccga tttattatta tcttgaacca 129840 cttctggttg agaagttgta ttagattcat taataagata agcttttata tctttagaca 129900 tttatttaac ttcctttcac atattaaatt tagaatattt aaatgtttga taagcaattt 129960 taacaataga atattaacct taatgaaaat atgaatagga tgtgaaatac ttgaagaatt 130020 tcaatgaagt agaaagtgaa ttaaaatatt tcatagaaca aacagataac gattcttttc 130080 ctgttgattt atatgataaa ttaattgata ttgaaaagta tgcagatgta gattctttta 130140 caagtgatca agttaggaaa tcggttaaat atcttgttgc tttaaaagat tcactagaaa 130200 gatttgaaat tgaaaatgaa cagtctgaaa tggcagttaa tatggttctt cataaaatag 130260 aatttttaaa agataagtat aatactcttt atattaataa acgtgttcca aataatggtt 130320 acatagataa tttatataaa gaagatttca gttctaatat taatacagaa tttaatttta 130380 aacaattaac tgtagcatta gctgaaagtc ctgctgattc taaactagaa agaaaagctg 130440 ttattaattt cttaatggaa ggtaatatga attatcttaa tgaatcttat gacgatgatg 130500 atgatgaaga ttatcttgat ggtcttgata gtagttttga aacttctaaa gaacctaaag 130560 ttgctgaaaa gaatttaaat agattaattg gttctgttaa aaaagcaacc gcttcttcta 130620 aaaatatgaa tgataaacaa ttagctaaag ctaatcgtat tagatttgta agagctttat 130680 taactggaat tttattctgt atcggtttaa aaattagttc agcagctatt ggtaaagcta 130740 aaacagcttt aatagggtta ttgactgtaa ttgtttataa tgcaagtaaa ggtaatgaac 130800 ttaatagact tatcattgta ttagaagaaa gaatccaaac tttagagaat agaattgatt 130860 cgactgatga tggagaaaag agaaaagaat taagaatatt aaaatcagat ttagaaggtc 130920 aacttaagaa agctaatttc caaaagaaat ctattgagaa aactaaaaat gcgatttctc 130980 gtggagatgt aaacgatagt gggtcagcgt atgactatta ataatagaga tcttttatct 131040 gaatcaatta aaaaattatt aaatggtaat aatattctta atgaagctga agatgatgaa 131100 actaataatg attcttcaga tactaataca gatgatacaa gttcggaaga tactactaat 131160 gataatgaag aatcttcaga agaaaattca gaaacagaag aagataatca agatgatagt 131220 aatgaagatg attctagtac agatgactct gaaagtgatt cagaattaga tgatggttca 131280 gaagagaatt cagatgaaga caatccttta gacgatcaat ctgaagaaga aaataatgaa 131340 cctaaagaaa ctaattctga taaatattta aaattacaaa tatttaataa attaaatgat 131400 ttaatagatg tttcattaaa atttaaagat attgtaaatg aaaagaatat ggaatctttt 131460 gataaaagtg aaaaagaaaa aatgagtgaa attacagtac agacttcaaa taatttagac 131520 agtttaattg atagtattaa tttatttaac aataaattta taaataatat tgatgctgat 131580 aaatgtgaga aactttataa gaagtttgaa aatacttata atgaaatctt caatatttat 131640 ttaaaagaat acaataaatt gaataaagac aaaaaaagca aatagtttta tatttcaaat 131700 tttattccgt tttattaata tttataaaat taataacatt aacatatgaa aagaaatatt 131760 tcattacaaa taatgattat tttttataaa caaatttata taataaaatt aataaatata 131820 aactacacgc taatatattt aagaaaagga gcagaaaaaa tttatgttaa acccaaacag 131880 aattaaagat gaattttcgg ttcgtttaga agatatcgaa aactctatta atgaatcata 131940 taaccttagt actatcggcg gagatttcgc tgctattgct actgacgatg cagtatttga 132000 aagctataaa gatcaattat tagaaggttt tgacgctgct gaaggagaag ctttagctgg 132060 aatgttagat aatactcgtg aagaaatctt aatggaatct tcaatgggac ctatccaacc 132120 ttacgcttca ctttctatgc ctattttagt taaactttgg gctcgtttag ctttaactga 132180 agctttacca actcaagttg ctaacaaacc aaactttaca gttccaatct taactccata 132240 tgttgtggat gcagatggta acaaacatgc tttaccagaa tcaattaata acacacctga 132300 aactttagtt ggattagttc aaattaaaga agatatcgca gttgaaggtg gaaaaattac 132360 tgattacgat ttatttactg gattaaaaga aggtaaagaa gttcgtaaag gtattgaccg 132420 tttagaccgt aaattcaaaa tcgttgaagc taaatggagt gattcattcg atgaacgtac 132480 ttcagctgca ggattcgttg aattaggttc taatgtagtt aaattacaag acaatgatac 132540 attagtagga caaattaaat atcctacaaa tggtgatggt gaagttgaaa ctgacactgt 132600 cttaggtaaa gtagatgttt ctacaggtga acttactttg acttcagctt caggtaaatt 132660 aactgatgtt aaagttaaag gttatgtagc ttctgaacaa catacttcag ctacaaacgt 132720 tgaacttggt ttaactcgta aagacgttgt tattgataca gctcaacaca tcgaagctac 132780 agtacctctt gaagtaattc aagatatgaa agctacttat gatatcgatg gagttgctcg 132840 tttatcagaa actatgtctc aattatctag tcaaaaagtt gacttagaca ttattgaatt 132900 cttagatcac gaatataaag aaactgatgc taaatatcac ttcagcttcg atgtattccc 132960 acatagtgat tacagtgctc atcctaaaga ttggttagaa ggtctacgtg aagtaattga 133020 ccacactact caatcaatga aaaacgatta caaattatat gacgttcaat tcgttatcgt 133080 tggtaaccca ttagacgttc gtttaatccc taacgtttct tggactttca atggtggaga 133140 ccgtaacgct gatgcttatt ctaacggaat caaaattaac tattcattag gtgctgcttc 133200 aggtactgct aactaccgta ttatcggttc tgacttagta cgtcaaggtg aattgactat 133260 tattgctatt cctcaacaag acaactataa aacattcatg ttctaccctt acacattcaa 133320 cgttgtaaat ggtggaggtt acctaaatac tcgtaaccct aatgttccta acatgatgat 133380 gactcgtaga tatacagttg aatcatttgt tccgatcatt ggacgtatta caatcaaaaa 133440 caacaacggt tcagtatacg ctcgataaga gtagtacttt atcattgcta tttatattac 133500 ccatacatct ctctgaggtg tatgggttta ttttatatca aaaaggagaa tataattcat 133560 tatgaattta caagaagaac aacaattaaa taaaattaat aaaataatga atatcaatga 133620 agatgctttt aattttagta aaaatacttc attattgaga gaaatagatg aagaatttaa 133680 aacattatta gatagttata attatgataa atctgatttt gatttaattg ataaacatga 133740 aataaataaa atatctacta atatttctaa aatcactaag aagctattta atactaatat 133800 gaaattaaaa tttgttgaag ctgatcctaa aggaaaagat aaatttagag ttgaatcaat 133860 tgcaagtaca attataaaac cagaacaaat tagaaataca ttagatggaa tttctaaaat 133920 agttatagaa gaaaagaatg gaatatatta ttctaaacct agagaaattg aagtttttat 133980 ggagttatca tctttaagat actttttaga aatgaaaaag aattctaaga aggtatcttt 134040 ttctaatttt aatgaaagag tttgtacttc aatattatta catgaaatag gacataattt 134100 atttttacct attgaaatta aagtaataac tcaaggtaaa gaacctgctt ttgagcttaa 134160 atataaagac aataaaccgg tacaatttca atatactaaa gatatagaag cggacactga 134220 tagaaattta aaattagctg gtcctatgat aatttctatg acactaatgg ttgctatttt 134280 aacttcatta acaggtgtag ctgctataac tggaattgct tctatttttt ctttctttaa 134340 attaggatca atggataata aaagagtaga aaaaatgaat tataatctat ctgaaagatc 134400 tgctaatcaa ttacctgctt tatatggata tgcaaaagag aatataatgc tttacgatat 134460 ggtttatgct gcaactaata gtaaaatgga aaaaactaaa aataatattt tcagtaaaat 134520 atttagagga ttaatgtatc ctggtagatt atttattaga aattataaag actattcatc 134580 agattccatt gataatacta ttaagactct taaatttgaa ataagtaacc ctaataatag 134640 taaagaagtt aaagaaagtt taaaacaaca actttctgat attcaaactt tgatgaagaa 134700 atcagataga atgtagataa gaaaagtgag ttgaaataaa tatgactact aaaccaaaat 134760 taaagaaaaa agtgtattac gattataaaa ctaataatgt tagtttttta agagtagcta 134820 gagatcttaa gaagaacaac gttagaaatt atggtattcc attaactcta tacgataaaa 134880 atcttatagg agtagatcct tgggatcctg agctttctga tgaaatgaaa actcgtgtat 134940 taagagaagc taaaattaat atatggtttt atcttagaga agttatccga gttccagttc 135000 ctggtggtaa agtaatgtat gaacttcata ggggtaatat ggctatgact ttctgtatgt 135060 tgcataacct tgatacagct ataatgcttc cacgtcagca ctataaaaca tattcagctg 135120 tatgttatta ttcatggata atgttattag taggtagtaa ctatacaatg ctatttacac 135180 ataaatcata ttcagataca acggaaaact taaaacgtct taaaaactta tttaaagaga 135240 agtgtttacc tgaatatgta ttagctaact ttggtgataa aaatgataga gataaaatta 135300 atgaatttca attagctagt aataataata cgattaaaac agtttcacct ccaactaaca 135360 gtgagagtgc aaacaaagca ggtcgtggtt ctactgtacc tatggtttgg ctagacgagt 135420 gggcattcat tccacacaat caaacaatgt ttgaagctat gagacctgca gtttctacag 135480 catctgcaat agctaagaaa aatggtacac cttatggact tctaattact actacaccta 135540 aaatgactgg gtgaaaataa attaaaattt attttaagga ctttattaat tgctgggaga 135600 gccttagagc ttaatcaact acaacgtaat tagaaataat aaacgtgaat gtctaaaaat 135660 gattaagatt ggtcaatcag cagctaattt ttcaatttat taaataatga acaactcctt 135720 atacaaaaga cttaggagtt ggtattttga atttttatga aaaactaaat aaaaaattta 135780 ataatagtat aatagcaaaa gaagaatata aaaatggtaa tgaaaaaatt aagttctatt 135840 gcaaaaattg tgaaaattat ttttattcta aacctagaaa aattattgaa tcttcatata 135900 aatcatgtca tttatgtaga aaaaaagaaa aagaaaatat tttcaggaat aatctaatta 135960 aaatgataga taatgaaata tatgaaataa ttgaaatgaa aaatcctata aagaataatg 136020 aaaaattttc tttaaagcat agaaaatgtg gaaatgtatt tcatatatct gtaagtaatt 136080 ttaaaaaagg tagaaaatgt ccttactgtt ctaataaatc tatgaaaaga gatcaaagtt 136140 tctttttaga gaaaataaat aatatagatt ccagtttttt aaaaaattac gaattagaaa 136200 gtgattatat cggtgttaat aaaaatatta aaattaaaca caaagaatgt ggaaatattt 136260 ttgatactac tcctaataga atatatagag gtaatagatg tagtatttgt tctcataaat 136320 cagataagta taatttagaa gaagtgaaga atattataga aaaagataaa aaatttaaac 136380 ttatgtctaa ttattatgaa aacaataaac aaaaattaaa aataaaatgc attaattgtg 136440 gtaatataca agagaagaat ttagtttcat ttcaagataa aagaaataga aaatgtatgt 136500 gtgaaaaata ttctatacca attcaatata taactaattt tctaatgaat aaagatataa 136560 attttgaatt agaaaaaaga tttgataatt gtaggaatat tagaccttta ccttttgata 136620 ttttcataaa cgattttaat attttaattg aatatgatgg agaacaacat tttaaaccga 136680 tatatggaaa agaaaaattt aataaaacta aaataaatga tgaaataaaa aataattttt 136740 gcaaaaaaga aaaaatagaa ctgattagaa taaattgcta tgatgattat aaagataaaa 136800 ttgaaaattt agttcaacga ctatcgaaag ttgagtatac atcgtgagga tttatacaat 136860 ataaatgagt agagtacagc caagcggtta gtaattaagt gatattagct taatataatt 136920 ctattaaatg gaaacataaa gatttctaaa gtaacgttta gatttaagat atagtctcaa 136980 cattcaggga aaacctgaag aagttcataa gagaactgat atagattagc gatctatatt 137040 gaagattttg agtactttag atgttcctca aggacaattc ttctttgaac aaatgaatga 137100 tgcggctcaa tggacagaaa aaatatatga ttattacatt aattctgaag aagaaggtaa 137160 tgaaaaatta gaagagtata tggatagtaa ttcaggtaat tcatttattt atatagaata 137220 ttcatataaa gaattaggaa aagatgacaa ttggttagaa aagcaaaaac gtcaaatcgg 137280 ttctttagaa gctgttaaac gtgagatact tcttgaatgg gcatttagta atgatgattc 137340 tttatttgat gaagaacaaa tgtctgagtt atctctatat gcaaataaag aaatatataa 137400 cactattgac tttaaaataa atggtaaaac ttattatgtt catatggtta aaaagatgga 137460 aaatatgcat gaaaagaact ggcttgttgg tattgacata tctggcggtc ttggtcgaga 137520 taatactgca tttactgtag ttgatccggg tacattagaa ccagtaatgg tcttccaaaa 137580 taatataatt aatggtccta ctttcagaaa attaattaaa gaacttatta cactttatat 137640 acctaatgca gtattaatac ctgaacgtaa ctatgctggt acagtaatga tagaagatat 137700 gattcaaact gataatattg gagataatat tttttattca ttaaagaata gaacagcaga 137760 aaaacaagtt gaagttaata aacaagtatt taatgaaatg cctagacata gcactaataa 137820 agttactaaa caagtaagaa gatatggtat cgatacaact aaaaaatctc gtgacttaat 137880 gcttaatgaa attttatcaa tgatagttga agaaaagcct tatctggtta ataataaacc 137940 attattccaa caaataaaat ctcttcaaat gaaaaaaggt agaattgatc atcctgatgg 138000 cggtcatgat gacttactta tgagttattt attctgctta tacgcatact attatgaaaa 138060 agatattaag aaatttgtta aagttaaata cggttcaata gtatctccaa ctggagaaaa 138120 tgcggaagag attgaaaaag aaagacaagc tagaagaaaa gatattgcat ccataaaacg 138180 tattggtgga attattgatg gtaattctcc tagcaatcct ctattacaga ataataattc 138240 cgctccaaat caaaaatcaa aaagaataat gaatttattg gattgattac aataaaggta 138300 atggcataat aatttgtcat taccttttta ttatcacaaa tttttattat tccatcttaa 138360 ctaatttgta taatagaatt tcaagaataa ttttaaatta gaattttttc taaatttaat 138420 agaataatat aatatataat aataaaacgg atggtgaaaa taaattggca aaaacatatt 138480 taattgacga taaagatgat ttagaaatgg taaaagaaga atatgatgaa gtcattatga 138540 atatatctga agacattatg attgataata ttaaagaaca aattgaagat tcaaattcaa 138600 gacagttcta tattaatcaa tatcataaag atttctttga atactttgaa attagattta 138660 aatttatttt agaaagatat aaagaagata atgatatctt aattaaaact aaacaagttt 138720 atcatgatat tcttaatgaa attcaagaat ctattgaaaa tacttatcag ttttctttag 138780 aatttccaga agatatttta attgaagata aagctcaata cattaaatca ttgtataatt 138840 tctttgtatt aaataaaaaa gaaactttaa ataatttatt tattaactat attgagaaga 138900 atataatgca attagctaaa acttataaag atagtatgga tgaagacgtt attaactctc 138960 tttcatataa taacttaaag aaaactattg ataatgatta tacaccttta gtatattcta 139020 ttcctgaaat tattgatggt attcatattt ctgataatga agatgtaata gagactatta 139080 tctatgatga agaatctgaa ttaaataact atcaaattga taaaatgtta gtagaacaat 139140 ctgtaacaga tgttagattt gataatcatt taattaatgt atttagagat tcttttatag 139200 agaataatgt attacatcga gaagttcaat actattttat agataagtat aaataataac 139260 atataaggag aaaagctaaa atgactgaag ataagagcaa agaattagat ttagaaaaat 139320 tagaacaaga tatagaacaa gctaatgatg aattcgaaaa agaaaatgaa aagattgaga 139380 aagagttaga agaaacaaaa gagggaatta ataaagaaat agcttcttat tatggtaaag 139440 atagtattag tcttaatgac actatttcag tagatgctaa ggttaataga taccaagaaa 139500 aattagactt tattaatgga gatttaagtt ttgatagtga agatgatatt cctgaaagac 139560 ttaaaccttt taaaaatatg gaaataaaag atactaaaca aattgaaaat attattcaac 139620 aaattaaaga cagtaaagag gctaaacatc ttgtagaaaa tattactatt agtaaattac 139680 ctgttaatga taataaactt aaaaaagtaa atgaaaaatt aaatatgaaa atttacagat 139740 ataataagtt acatggtaat gaaaataatg aatataatta cattgattta gaagatattc 139800 ataatactct aaaaaatgct ttagacaacg atagtttcaa agaatcaaat acattataca 139860 aatttatgtg tgcattaggt tcatacatgt cgcaaaatta tgaaaaatat ccttactata 139920 taaaatctct ttctgaaaat gttgactaca ttggaaaatt cggtaataaa ttagatcaga 139980 acgaagactt tatcaaagta ataaatagta ttcttaagaa atactaaaat atattattaa 140040 aaattataag aaagaggttt gattaaaaga tggaacaaat taaattttat actaagaata 140100 actgtgctaa atgtggtttc agtaaaatgt ttttaaataa taaaggtgtt gcttacactg 140160 aaatcaatat tgatgaagat gaaagtgcta aagaagaact tttatctaaa ggataccaat 140220 cattacctgt aattgatttt ggaacagatg taatcgttgg taatgatcct gctaaattaa 140280 atcaaatttt atctacagtt actgcttaat taaatataaa ggagattata attatgcaaa 140340 ctatttttaa tagtccagaa gaagtagatt ttaaaaaatt agctgagaaa gctagaaata 140400 atgataatga attaaataca aaagctgttc atgaaggaga atacaattac aatttcagta 140460 ttgaaggttg gaattactca ttcagttcag atggaactta ttggaaatgg aattatcaac 140520 aagttaatca ataataatga ttaataaaaa acgatctatc acagagataa tctgtgatgg 140580 atctattttt aacgaaaaat tttatatttg gagagattta aatgaaatta ctttatttct 140640 cattaacagg aaatagtaaa aaatttgctg agaaattaga tagctctata gtaggagaac 140700 ctattgaact taatagagat aattgtgatg atattaaaat ggatgaagag tatgtattag 140760 tatgtggatc ttacaatact cctcacgcta tttacaatca tgtagaaaaa ttctttaata 140820 atggtaataa tttagaatta tgtaaaggta taattggctc aggaaataga aacctaaatt 140880 atcaattctt aactacacct aaaagattat gtagtgattt taatttagaa ttgattgcag 140940 gagtagaatt gtttggaatt aaaaatgaac atttagaagt aaataaaaaa ttagaagagt 141000 tatctaactc tagtattata aattaatata ttgtaaggag acttttaata aaatgccaaa 141060 agaaatagac ttaacttcag aaaaatttaa agattattca tataacgaat taaactcaag 141120 aggttcacaa ttaaaagatg gtaatttaga tttagaattt gaattagcat ctgttaaaaa 141180 atatttctta gattcagtta ataagaatgt aagatacttt aaaacatata aagaaaaaat 141240 taattattta gttgataatg attatattga tggagacatg atcagtaatt atgattttga 141300 atttattaaa ggattaatga aagaattaat ggcttataaa catagattca ctcgtctatt 141360 aggagctaag aaattctatg aacagtatgc aatgaaagat gatgcaggag aaattttatt 141420 agaactatat gaagatagaa ttttatttgt agctttatat ttagctgatg gtgatgaaga 141480 attagctaga aatattgcta atgaaattat tacaggtact ttccaacctg ctacaccaac 141540 attccttaat gcaggtagag tacgttctgg ggaattagta agttgtttct tattaactat 141600 ggaagattct ttatcatcta tttatagaaa tatttctaac gtggcacaat taagtaaacg 141660 tggtggagga attggagtat ctttaagtaa tttacgtgct gacaatgatc caattaaagg 141720 tgttgaagga gcagcttcag gagtagttcc agttatgaaa gtatttgaag acacattatc 141780 gtatgtaaat caattgggtc aacgtaatgg tgcaggtgca ctttacttaa acattttcca 141840 taaagatgta gtaaaattct tagatactaa gaaagaaaat gctgatgaga aagtaagatt 141900 aaaaactatt tcattaggtt taacagttcc agataaatat tatcaattag ttaaagaaaa 141960 taaatcatta tatacattta gtccatatga tattaaaaaa tattacgatt tagatttcga 142020 tagtattgac tttaatactt actatgatat ctttgtagat gataaacgta ttagcaaaga 142080 gaaaatgtat gctcgtgatt tagaaactac tattagtaaa ttacaacaag aatctggcta 142140 tccttatatc attaatattg atactgctaa tagagctaat ccaattagtc atggtacaat 142200 taaaatgagt aacctatgta gtgaaatttt acaagtacaa tacccttcat tagttgacga 142260 taatcaacaa tatgttaaaa caggaacaga cgtttcatgt aacttagctt caactatcgt 142320 acctggttta atgaaatcag aagactttgg taaatcagtt ggaactatgt taagaagttt 142380 aaattcagtg gcagaaaaat ctaatattga agctgtacct acagttaaga aagctaatga 142440 tttattccat acggttggtt taggtgcaat gggattacac acatatttag ctgaaaatca 142500 tattcaatat ggatcagaag aatctaaaga ctttactaat atttatttca tgttattaaa 142560 ctattggaca ttagttgaat caaataaaat tgctaaagaa aaagatgaat cattctactt 142620 atttgataaa actgaatatg ctgatggttc ttactttgat aaacgttata ttggtaaaaa 142680 tattcaacca cgtactgaaa aagttaaaga attatttgaa gatatcttta ttccatctga 142740 tagtgattgg gaacaattaa gaaataatat cgttatggat ggtttataca atcaaaatag 142800 attagctgta gcacctaatg gttctattgg ttatgttaga gaagtatcac cttcaattca 142860 ccctattgtt gaattaattg aagaacgtgt agaaggtaaa acaggtacta ctttctatcc 142920 agcaccaggt attacaccag ataactttga ttactttaag aaaaatgctt atcaattaga 142980 tatgagagat atgattgatt tatattcaga agctcaatat catgtagatc aaggtatttc 143040 tatgaatatt tatttaatga atgaacttga tccagatctt tatgaatgga aaaaagattc 143100 tttagataaa gaaactacta ctcgtgatat tagtagatta cgtaactatg cttacagtaa 143160 aggtattaaa tctatgtatt atactcgtat ttattcacca gaccatgatg aaaattctca 143220 aggtattgtt gaatgtgaat cttgttctat ttaattggag gtatttaata tgacattaaa 143280 agaaaaattt gaaagtaaat atagaaattt aaataaagaa ccagaaattt taattgtagt 143340 aattaaacta ccaagtggag ctaaggaagt aatttccaat agctctgact tggataataa 143400 agttcattat tacttagaaa attatgatga tcaatttaga catgttagag atagcaatgt 143460 acagataatt gatttcgtat tagtttaaaa ataaagaaaa aggatgaagt taaatggata 143520 gaggagattt cttaacaagt tatacaaaag ataaaggtta ttatacacct gtaaattgga 143580 atagagtaga tgattatgta gatattatga catatgacac tttagtatct caattttgga 143640 catcaacacg tattccagta tctaatgata ttaaagcttg gtctaatact gatgatttaa 143700 ctaaaggagt agttaataaa gtatttgctg aattaactat tttagataca cttcaatctc 143760 gtgaaggttc tgatgcttta atgcatagtg cattaactac attagaagaa gatgtattaa 143820 gaaatatcgg ttttatggaa tcaattcatg ctcgtagtta tagtactatt tttactacat 143880 tatgtacttc aaaagaagta gatgaaaact ttgaatgggc agaaaataat aaatatgtac 143940 aaaagaaaat taaattaata aatgaagctt atcaatctgg agatattctt aaaattcaag 144000 cagcttcagt attcttagaa tcattcttat tctattcagg tttctatact cctttaagat 144060 taaaagatag tcttaaatca gttcttgaaa tcataaaatt aatcttaaga gatgagtctg 144120 ttcatggttc atatattgga tataaattca gtaagagatt tgaaaaatta agtgaagaag 144180 aaaaaaatga aactaaaatg tgggtaaata acttactatt tgaactttat caagttgaat 144240 gtgaattcat tgaagaagtt tatactgaaa ttggttgggc agaagatgtt aaattattcg 144300 ctcaatataa tgctaataaa gctctattaa atcttaaatt agatcctatt ttcgaaacta 144360 ctgaagaaga tgtaaaccct atcgtaatgg caggattaaa aacttctaca ggaaatcatg 144420 acttcttctc tcaagaaggt aatggttatt tattaggtaa agctgaaaat actaaagaag 144480 aagattatga ttcaatcgat attaatgaac ttaataagaa tatcattgat tcgtataaag 144540 ataaagcaga cgatagattt agtcatagtt actatataga ttaataaaaa ttttattgaa 144600 tgattaacaa atatagtata ataaaaataa aaaaggtaat ttgtttttat tatgattaat 144660 ttgcatacat ttcccctaac attcttaatt gattgttagg ggatttttta cgccaaattt 144720 tgatctgtaa caaagatata ttaattcaat taatgggaaa ggagataaaa tggattgaaa 144780 cttaaagaac ttaaaagaga tggaaattct attatattca ctggtgaaat attagacatt 144840 tacattccaa gagaacaatt caaaaaaggt ttatcagaac atcgtggtga gtatattaac 144900 acgtatggaa tgtttcaatt tgaaataaaa actgagaagc aagctgaaga aggtaaacaa 144960 ggtgttttaa gaaaaatgaa atatcctaac cctatcgatt ttaactatgt agagaatttt 145020 aagtttgatg gaaaactgtc agataacatg gattcaatac aatatgaagt ctttagacta 145080 agaaccggat gtcaatttgt agctaatgtt aatatagaac aatcagctga aactgttaag 145140 aatttcttat tcttattcca tgcaggtaaa ttacctactt ttatagatta taatgatatt 145200 attaaacttc attatgatgt attggatagt aataaagtaa accttaaatc taattcatta 145260 acttatgaat tgattattgc tgaattatgt agatataaag aaaatgtaga aacgccttat 145320 agaatagctt taaataaaaa acaaaatgtt ggccctttag attatattaa ttacaatctt 145380 aaaaaattac ctaaccttaa ttctacattt gcttcattca catttgaagg tatggatgat 145440 actattgtga catctatagg tagaactgct aaaggtggaa cagaaaaacg ttcaccatta 145500 gaagacgtaa tgaaatatta ataagaaagg atgaatctaa taaaatgttc tggaaagtat 145560 caaagaatct cttaaagtta tctagaagta ttttaacatt cattgaactt aattcaaata 145620 aaaagaaata tccaccttat ttagcttttt tagtattcca gaatagtata acaatagatc 145680 aagttcctaa tgaatttaaa gaagaagttc aatatttatt ggatgaaagt tttaaataaa 145740 ttatgattgg tatcattgta tatacttttc taaattaaac atactattat aaaatttaat 145800 tataatataa aatctattga aattaatcac atagatgtaa atattcgaaa ggaaggttac 145860 aaaacatatg gcagacttta tgtatctcca tccttctgta caaacacaaa tcaactctta 145920 tcaaaataat taccctacag ctgaaggtcc tgtaacatta tttgctgcag acacttttga 145980 aaaaggtaaa gatggagtta ttgattttgt aggtactgaa gaagaattta tttttaaata 146040 tggtgaacca aactatacga aatacggtca agctgcttat aacctcgtga actggttacg 146100 ttctggtggt caagcttatg tattacgtgt attacctaaa aatgcaactt actctcatgc 146160 tatattaaac gtacaaagta gagtacaaaa agatggtaaa aaagttttaa cggatgcaaa 146220 tgaattagtt aaaattgatg atgttaaaat tcgtccaaca attgcatttg ttaagaaaaa 146280 taatagaaat attgaagaat tagttaacga aatcacttta gatcgtggta atgaacaaac 146340 agtagacggt tataataata acttcttact tttagcttat ccaaatggtc gtggtgaatc 146400 ttataatgat ttaggtattc gtttaacttt aaatacttca tatgacacta gtggtcgtac 146460 tgaacgtgtt tataacttag aagtacttga atttgacgaa tttagtaatg ttaatgtaat 146520 tgatggccca ttcttagtta catttgatcc agattcaatt tcagatactg gtgaatcaat 146580 gttcatcgaa gaggttgtta atcgttattc taaatacgtt aacatcaaat ttaatctaga 146640 aaacttccaa aatctagcta aagaaattaa tcctaatgta catcctgcaa gcattgatgt 146700 tatttctggt aaatctaaag ttagtattga tggaactcct gagactttct actcagaaaa 146760 aactaaacaa tctgaagata tccatatcac tttacaccgt tacaataata aaggtgtacc 146820 agtaactatt agtggtaacc ctgtattgaa taaacctgat tttaacgatc cagttgaaaa 146880 tgcattaatt tcattagaca atggtatgcg tgaaaaaact ttcgttacag attcagatcg 146940 tctttcttac atgagagatc aatacaaaac tttacgttct gataatttta cagaatttaa 147000 atcattatta aataaaatta ttgtaccggg taatggttta tttgaagatg atgcaggtag 147060 cttacctaaa actattaaag ataatttagt ttctgcaaaa ttaacacaag aagatgtaac 147120 tgcagatatc aatgatgaag aagcagttga agaagaatta gctggaaaat tcaaaccttc 147180 tgaaattaat ttcggtggta aacctgctgg agcagctgaa cgtttagttc aagattataa 147240 cacttatttt gaagattcaa atgaagaaaa tctttctgca gtactttcag gtacagaaga 147300 aattggttct ttattattaa acgaattctt agataacggt aataaactta acgctgctta 147360 cgaattagtt tataaatcta attcaggtat ttcttcaaat cctaaatatc aagctgatgt 147420 taaagaatta cgtgatgtat tggctcaaaa agaccaaatc cgtatctttg gtattcaaca 147480 taaatctaat atcttagata ttacaaatga tattgctgaa ttacgtattg gtatgaaatc 147540 agttactaac ttagaaggta tgtctaaagt attaaatgat actgaaacag aattacgcta 147600 tgtaattgac aacttaatgc ctgctgttcg tgaaggactt cctaaagaag cagttgactt 147660 tattaacact gttcctgatg gtgatgatga agatacagaa cgtgatttag tttctccaga 147720 agctatgtta aactcattag ctgacaaaca aatgttagtt gacgatatta acttaggatt 147780 aatggaagac aatgctgcta accgtgaaga agtattcgta gcttgtaatg aaatcgctaa 147840 ccaattagtt gatttaatta acagagctgt ttcagtagct tctgtatata aagttgctcg 147900 tgcggtacgt attgcagcta atacaatcta ttatgatatt tctatcttcc gtaaaaatat 147960 tgatgaaatg attcaaactc gttctaacta tacagaaaga gatattacat tgaatgctca 148020 tcaaaatatt gaattagctg ttgctaactt gaataaagct aactctaaat acttcaatac 148080 taatcttatt gatgtatcta gtccagttaa attcttattc ggttctgatg gtgacttctc 148140 ttatgctgaa gacatttcat ataaagatcg taaaaactct gttaaccgtg aattaattaa 148200 agcttataaa ggtttaattg atgaagaaat tacaaacact aaagcttatc catttgatgt 148260 tgttcttgat gctcgttatt ctaacgaagt taagttcgct atctctgaat tagctaaaaa 148320 tgttcgtaaa gactttgtat tcttagctga tacggttact gatcgttacc cagttagtcc 148380 tgaagatgca attagatgga gaaaagaaga atttgctgtt tcttctgagt atacagctat 148440 ttactctcaa gatttaactt actatgatga gtacactggt agagacattc gtttcacacc 148500 aacttatcgt ttagcttcaa tgattcctta tcaagctgtt aactctggtt tacacttccc 148560 aattgcagga cctagacgtg gactagttga aggacataaa gctttatctt gggctcctaa 148620 tgaaccttat aaagaaaaac tttatacttc taaaattaac tacattgaaa aagatattga 148680 tagaactaaa tttggtgcac aaatgacttc tattaaatct gatggtccat tatctaactt 148740 gaacaatatc tttacattaa atcaaattaa acgtgatgca gaaactcttg tttctgatta 148800 ccaatttgaa ttaaatgatg atgaaactcg ttcaattatg ggtacagagt tgaatgctta 148860 tcttactcgt tatgtatcta accgtagctg tgaaactatt caagctgaag ttagtgcaga 148920 tgaatacgat aaatctcaac gtattgtacg tgttaaaatt tctgttaaat tcaacaatgt 148980 tattgaacgt atcttcattg acattaatgt tgaaaaataa ttaaacttat aggatacggc 149040 ttaatataca gtcgtatcct attttattat ataaataaag atcttatatt aaattatacg 149100 tatgaagatg gtatataaac ttctataata tacatttatg taaataagat taatgaaaag 149160 gagaaaataa tatatgattt taccaagtaa aaatcagcgt gtgtttgata ataacatcgc 149220 taagaacaag tggttctata atggacatat gaatcttcaa actcttgagt ttgatccatt 149280 cgtaactggt tattcattca tagtatggac taagattcct tcttgggttg aaaaacaatt 149340 ccctggtttt aaagctatga ctcaaaagaa ctttaaatca ttccaaggtt tagaaaacat 149400 tgaaatgact acaaacgatt atatgcatac gtttaacggt aataactatc gtacagctgc 149460 tagtattaca aaaggaaaca ctggtttcca aatgactcac caagaattct ctggtagtcc 149520 aattaaaaat atgtatcaat actgggtatc tggtatccgt gatcctcgta ctggtattgc 149580 aacttatcct aaaattcata atttagaata tgctgctaaa aaccatacag gtgaattatt 149640 atatattcaa actcgtccag atgctaataa tacatctaaa aataatattg aattcgctgc 149700 ttattacact gcagtaatac ctactcgtat ttctcttgat caccataact acactatgga 149760 aactcatgaa gaagcacaaa ttgagcaaga ctttgcaggt aatatggaaa tttcagcacg 149820 tgtaaatgac tttgctaagt ctaaacttaa tgaaatttac agcttcactg aacaaggtat 149880 gtttgatcca tctgcaccta aaactgctgg agataactta tctgatttcg actataataa 149940 aggtggaatc actggttcag gtaacggaga tcttaaataa tagattctct caaataaaat 150000 cccctaatac taaattaata gtattagggg aatatttttg aattatttat taattctact 150060 gtatatatga caaaatgtta tgtcgtctaa atttactgtt tcatttagta atctttcttt 150120 ccagttctct ccaagatcat atatcatttc tgataatact ttttctgtat aattttgtaa 150180 aggaactagt ttagcatcat atttactgaa ttttcgtata tagttttcat aacttaaatc 150240 gtcagataca tatttaatag attcaaatat ataaggttta aatatcatat atctatcaaa 150300 atccatatca tcatgaatca tcaataattt aggtaaataa taagattcaa taggtacttt 150360 aatttctaat ccttgaatat tatttttata atgaacttca tattttaatt ttctatcttt 150420 ccaatcaaaa ttattaagag cgtaatgtat aggttcttct tcaatataat aatcgattcc 150480 atcatcacta tataattgaa cactatcaaa tgatctagga tcattatctg aatcaatatt 150540 atttaactca ttatcttcat tagtcattac ataatcttca tatataaaat aataattttt 150600 aatattagga tacactaaag cttttttatt aacatctgaa tgttttttga ctgtatttga 150660 atttataata agagaatcaa ataagaaatt atttttgtca ggtgtagtta tttgtatatc 150720 attttctttt ctaagataaa tttcattgat atattcatct atattcattt ctggaaatct 150780 cttatataaa cctaatgtac ataaattgtt atgatcttca tgaactttag caatataatt 150840 tttaccatta atatttacta ccgcttcttc ttgtttagaa ttctttattt gatcattatt 150900 aaattttctt ctaaataata ttttgaaatc atacattcca gattcagata aatttaaagt 150960 attcttaaca gttcctgtag ttaaagaaaa tttatcagat aaactactaa cttcttctat 151020 atttgtagtt ttattatcta ttttaaaagt ttctaaagtt ttaccagttc cctgattata 151080 agaatcatta tctatataga aatctttaat aggtactata gttctagttc ctactttaaa 151140 gtgattttct tgttttgaat agaaaggatt tttagcttca ggaacttcaa cttcttctaa 151200 taatataaca tttatatcat tttctttagt agagaagttt ttatcatatt caaatttaaa 151260 tgtatgagtt ccttcctcca agtatattgg tggctcttca aaatattcat ctgtagcatc 151320 atcatatttt tctaatatag atctaaacca taataaactt ttattcgtag gagtcctaaa 151380 ataacttcct acattatcta taaacacttt attcactgta ccattattat aatgatttcc 151440 agctttaaat cttacttcat aatgggatga tttaggaata ttaattttca tttctaatat 151500 tccatcttct atagtcacat atccttttcc taagaaccta tcataacctg aatctctctt 151560 ataagctcca tcaaattcac tttctctagt tctataaaca tcacctaaat atgcatcata 151620 gaatattctt ccatcttcta ctaacccatt atatataata ccatctatta attcagattc 151680 ttttaatatt tttttattaa atgcatagtc tttaggataa ttattattat ctttatagac 151740 tggtggataa ggttcaattt tcacctcact ttctaccaga ttgttaaaat ttaaatcttc 151800 atactcaata ttacctatat aattggtatc atatattctt tccattttac ctaagtaatt 151860 ataatatatt gtaaataaat catattttaa ttcaccaatt aattcataag gtctttcttc 151920 ataaactaaa acatctttag ttaattcatt ttgatttaat ataggatttt caattccata 151980 ttctttttta atataggaag ctgattcaaa taaattaacc tcaccatctt ctttaaaaga 152040 taattttttg tattcatcag aatcaaattc tatttttaat aataattttt ctttcttttt 152100 agttttagtt gtaatcaatg gtctattttc attatcttta attttagtaa taacgatttc 152160 accattatta tttttatcaa ttaactcttc tattctataa agcttcattg taataactca 152220 actctcttct ataatatttt atgataatgc acttccaata gcactgttag gatgagggtt 152280 tgcttgagat ttataaccgt aaatagtatc atctatttgt tgtttaaata ctcttccttt 152340 taacacttgc atacttcttg aatactgatt ttgcatatta atttgagctt tatctataat 152400 tgatagttga tctcttctaa tacctgctaa acaatcaata taagaaatta aacctgtatt 152460 aaatttcata cgttggaatg attttgatgc cattaagtta gggtacatat ctcttacatt 152520 tagtgaaact gttatttctc tagggaaacc atctgctgtc catgtacctt cttctccacg 152580 aactatattc attgatgtta taatacctgt atgacattca aatctaccag gacagtttgc 152640 tctaacaatg aatggttgtt tatatgagaa aatagaatct tgtaaaggta aagctaatac 152700 caataatgac atgaacggta aatatacatt ttcaaaaata gattgaggat ctccatacgc 152760 actatagaat ttaaattcta agttataagt acggtcaaaa gttgagttca tccatacatc 152820 aggataatac attgatgctc catctaaatt ttccataaag ttaccaacta taccacctaa 152880 tactggcata tttgcaacca tatcattaat gctatcttta atagatcttg taattttacc 152940 taaaatagaa gctcctccaa tacgagccat ttctttttct tcacgtattt cttggttttt 153000 attattaatc tgagaagcta tatcagattg attatactca tgcattgctg attcagacac 153060 actagtagct ttatccgcat aataagctaa accatagttt ttgtcatcta aagatccacc 153120 taaatcaaat gatcctttta atcccataga tgcatgtaat tgacttccca tggtttgtac 153180 gtatttataa tattcactca ttttaggttc aaaactaacc atacgtccat ctttagtatt 153240 acctatacca actaacccag ctgtagtatt tgctaatctg tctaaacctt ctccaaaact 153300 ccataattta ccttcacctg gtttaccgaa tagtttacca tttagtttag gcatacctgg 153360 cattataaat actaatggta aatctaattc aaatgtcctt ttataaatac gtctattagg 153420 atcatctaaa ctggagtaat acataggcat tccaaaaaca tccagttcac ctttaacatt 153480 tctcaattta gttttatcgg atgctccgta ttcagaaatc tcacgactat tacctaaagc 153540 atctttaaat acacctaaat cattttgact tggatcatat tcttggtaag cataatctcc 153600 tttagtctca tcaggtttag gtattaaagc aatatcatca tcactaatat taagtttatc 153660 ttgtgctttt tctctagctt ttttatcagc tttttctact tgttctttta tatctttttc 153720 attaggcaat tttaaattca cttccttttc atttcagaaa taatatatgc ggatatgaca 153780 tataataaac tgtcatatcc gcataatctt tactatataa aagagttgtt cttctattta 153840 ttcaaatcat taactttatt tacctgaaaa tactggtata gcagatctca catcaatgtt 153900 gaattgatct ccataagctc tattaatagc ttcttgaaga tcagaatctc cttgtgaagg 153960 tccattatta ttacctggat tgataataat agtacttccg tttccattat taccacctgt 154020 accaggatta tatggatcat taggattaac aatgacatta ccattattat taccattagc 154080 tccattgttt ccattttgtc cattatttcc agtattgccg ttgctaccat tatttccatt 154140 tgcaccgtta ataatatctg ggttattttg taaattatct ttaatgattt tatcaatttc 154200 tttattaatt tctttgataa ttacattacc tttagaatca actaagtcac ctttattatt 154260 gatagttgtg ttattaaaga tattatcacc tttattaata gtagtgttat tacctttaaa 154320 tgacattttt ctaagctgat ctaacatctt agctgtattc ttatcaatat tacttgtatg 154380 cttagtaatt tcatctaaat ccatacgttt ttgcttatca actttcatag gtccattttt 154440 gtaagatact gtagaattgt tataattatt ggtaatatta taaatatttc ttacagtatt 154500 attatcgcct tgaattgttt gatgagtagt agaattgttg gttgtagttc ctggtgaagt 154560 atagttatta ttaactatag tagaattagt atttccacca ttattaatta cagtacttcc 154620 accagaagaa cttcctgatc cttgttgttg agattgattt ggcattgatg aagatgaccc 154680 atcttgacca tttgcaccag attgaccatc agaaccacta gatcctgatg aacctgaaga 154740 accagagtct cctgattcac catcttctcc atcagatcct gatgatccgg attcagattt 154800 cttcttaccg gcttcagatt taagcttttc ttgttgttct tggtctattt ttttggcttc 154860 ttcgtaatca ataccatata tttgagcgta acgtttcatt aaacggtcat ttaatgcttc 154920 ttgttcttct tcatccatac ggttatcgtc acgtccagta atggatccgt accaagtacc 154980 atttttgaaa ctatattctg aagctcctgg tgaatctcct gattctgaac tttcatcact 155040 tgagcttccg ctatcagaac ctccttcacc atatctcata taaccatcaa ttccccattt 155100 agggttttta tatttattag cactgttaat aacaacacca tcaacaccat tagcctctac 155160 ttgtttacct ccaccaatgt acattgtaac gtgttctata ttatcacata aaataatgtc 155220 acctggttta aggtctttgg ggcttttagc tttaattttc ttaaaaggcg tatctccatt 155280 ccagaatgaa tgagtagtgg cgttcttatc catatctaaa ccagctttta cataagctct 155340 agctatcaaa ctagaacagt caaaagaatt agctccttgt ctgttaggtt gtgaatattt 155400 tgcaccaacc tgtttcttag cccatgcaac agctttatca attttggctt tttgacttcc 155460 gccaccgcca ccgcctcttt gtataggtgg attaccttta attattcctg ttctacgtga 155520 gcttttgttt tttcctgatg tagatgaaac catgttagaa aatttactaa tatcatttgt 155580 atcagctata actgaaccgg ccccacctcc gccagctcct ccaccttttt tcttagtaga 155640 ttttttacca gaaccactga attgtttgat aaaagcatta ccagaagaaa tacgtgaccc 155700 taaagcagga acgccagctc tttcatattt acttacccaa gaagcagctg cctgttctac 155760 tgttttagta gttttaaggt gagataaggc agcactttct gatccactta attctttcca 155820 taaataatct aattgtaagt ctaaatcaga ccatttttta cctttttctt tagcatattt 155880 cattaaacct tgtctacgag tattatccca ttgagcaata ccaataccat aaccagaaat 155940 agcactatta gcttttgctt catcaaattt ggcatctcct tgaacacgat cagctttcat 156000 tccagattca tgtgcaaagt tacctaaaac accagcagtt tgttcatcag aaagtccttt 156060 atctttaagg aaattccaaa ttttctctgc accttcacct tcaattccgg ctgcatcact 156120 tcctgaagat gatgctgaac ttgatgaaga tgatccagag ccagccataa aaccagccat 156180 gatatcattc atcattcctc cgagcttgtc aaaccagtct ccaatagtgt taactacttc 156240 tccacctggt tcatttatat ctaatttaga ttttttcttt ttcttcttac ttagtagaga 156300 ataaaaagga gacatacgca tcatagtttc tgctaatttc ttaggagcct ttttaagttt 156360 actcataaga tttttaggca ttaatttatt catttgatga ccaattctac ccattactga 156420 taatggtgaa tttttcatag ctccgtctac atctttttta atgtcgtctc tagtttttcc 156480 tgctgattct tctacttgtt tcttagcatc tttgttagct ttatctgaca ttccattcat 156540 ttcagctatt tcttttttag ctctatcaga tgcttcactt tcaattcctt cttgatatga 156600 gcttaattct tctttactag cttcagtcat ttctttactc atatttccca tttcttcttc 156660 atgactagag aatttgtctt ttaaccatcc ccaaccagat ttaattaatc cagttcctcc 156720 ttgaagaagc atagaagtca taccagttaa attacttaag cctttaccgg ctaatgctaa 156780 aggagccatc attaacatag aagcaccacc gacaactttt ttaatcaacc caccaaagcc 156840 acttgatttt tcttccatag ccatatcagt ttgatctcca aagcttttag ccatacctgt 156900 agttttctga accatgttca tacctaaacc aaatgctggt tttacaattg atttatataa 156960 tcccattcca gctaatccta ataaaggagt agaagctaat aaaggattat ctttaataaa 157020 accgcctata attgaagatt tatctacaga accatccatt ttagtatcaa ctgaaggatc 157080 aactgcaaaa ttttctccac caggttgagt tgaatctaat ttctcttgtt cttttttagt 157140 tttagaagga tgatcattga atccaataat gctacctaat gttttaattg gatgttttaa 157200 tgattctata ggatgagtta ttgttctaat aatatctggt ccagctaatg ccaatgatgc 157260 aatttgtcca ataccaggta tagcatttac tccaacacga gcacctactt tagctcctgc 157320 tttaagtaat cctttaccta cagctttttt agcacctttt ccagcagcca ttttagcagc 157380 tctagcttta agttttcctt taagtctact acctgcacca gccattaaag caccactagc 157440 agcaaatttg ccagttaaag aaccacccat gctagttact ttaccaccta atttagtatt 157500 agataattta cctatttttt ctttaacaag atctttacct ttgtttttat atttatcaaa 157560 tttttctttg agatgtttat taccctcaat aaaatcttga gcttctccta ctttatctgc 157620 aaaatcttta tcatctgaat tgtcagaaga tttagcttgt ccattttcta aagtttgttc 157680 attaggaata atagtagatc tattatcttc atctttaata ttatcatttc ttgtattatc 157740 agattttcta ctttgatttg tattagaaga tgctgtagaa gtatttttat ttaaagtttg 157800 ctctctagga tctatttctc tagaaacatt atcattaggt tgattcacat cactaattat 157860 accacttgaa ttactgtcac tagaattact gttatatctt ttctcaggta ttttgctatt 157920 tattctagat acaatttgtt taatttcact tatatcttta ttaacgatat tgaagttaat 157980 attatcgtat actgcatctt tattagtgct aagaatacca cttccatttt cattatttaa 158040 tttagaagta atatttttag aagtaccttt tcttttattt tcatcattaa gagcatttat 158100 agaactacta gatagtttct tcttaatatc tttagattct ttatttaatt gcattctagt 158160 tttagttaaa ctagttttag cttctttatc attaaataat ttatctagga gaatattaaa 158220 tggatcattc gggtcatttg atttaacctg atcaagttca ttgcttttat taatattttt 158280 agaaataatt tctttaatct tagatgtagc tttatttttg ttatcttcat tactgaaaag 158340 atcaattccc atttcagaag ctatattttc aaattcttta gtaaaactag attccttgat 158400 agttttatta actttttctt ctatatcatc tttaattgac ttagaagttt taaatgaacc 158460 tgaatcatag tcataatgaa tttcttgccc atcttctgaa gttaaaccaa ctattttaga 158520 taaataacca ggtataactg tattaagtgt attatgagtt tctacatcaa aagcaacttt 158580 ctgatgtcta tcttttctgt tagcagttga tataccacca tttacactat caaatatttt 158640 atcaattaat ttacttttac ctgatttaac atcctcaaga agatcatctc ttcttttatc 158700 tctttttctt tgtttagtac catcgtcatt atctttacca aaaggaataa tttttttatt 158760 ggcaaattta ccaactgctt tttctatgaa agtattttca ttattaagaa aatcaaaagc 158820 tttaccttta gctacatcaa ctaaacctaa atttttaatc ccttgctttt tagaaccgat 158880 aacttcttta agcaattcag ttccttgttt tttaataaag tctttagctt tatctttgaa 158940 tccttcttct tgagatcctt ctaatatatt tgataaagtt atattagata ggaataaatc 159000 ttctaatgaa ttactatttt taatttcaga tatattctta attttagtat tatgtctaat 159060 agcattacta gtttgaatta aaccatttaa gttctggaac atactttctc taatactatc 159120 attagcttct ctcattaaat taagattatc aatcatagaa gtaaacccag tagtatttat 159180 ttgagaaaga ttagatacag aagaagttaa tagagctgta gatttagcag aagaaccgcc 159240 atcattaata actgttgtag aagatactat tttagatttg ttatcttctt ctccgtcaaa 159300 gtcatcaaat tcaaaatctc catctaaaga atcatctgtg tcagaatcca tatctgaaaa 159360 actatcatca aaaccaaaat cttcaaaatc accaccgata tccataccca tgttattgaa 159420 gtcttttagt gatcctttat cttggatagt ttctccagtt ttaaaggtat ttttagtaga 159480 ttctaaagct tctttagata aatctttagt agattcactt atcttttgta attgtttttt 159540 ctttttattc tttaattctt tgacagcttt taatggatta ttttgatcca tcatacgttt 159600 catgtcatta gacttcattt tatttaaatt tttgttaaat tcaatatcta tatattttct 159660 agaagattta gaggaggagt tatttctaaa ctccttctct atcttgctag tgttaaattt 159720 cttatctcta gccaattatt agttccacct cctgctatct atttcaattc ttctaataaa 159780 cggtctaatt ctttagtaga tgctaatgta tttttatcta tattagctaa cattcttact 159840 aaatcatctg aataccataa tttttcataa tcataagtat aaccagagtt accattttca 159900 attttagaat ttttatgatt gtttacaatt ttattataat ggttagttac tcggttttta 159960 ccttttataa attctttatt cacattttca ttattaatga cattactttg tccattttga 160020 taattgttat taactgtttt agtattttta ctaccttgat tgttaacagc attattacct 160080 ctattaatat tagaaaaacc actattagct aatgttggta attggaatac cggaggattt 160140 ccgatattct tattattagt tatttgagat cttgattctt gtggtttaga tggcgatgct 160200 gaagaatcag aactatctga agattcttca tctccagaat cttcacttcc agatcctgat 160260 gaacctgatc cggattcaga tttcttctta ccggcttcag attttttctt ttcttgttgt 160320 tcttgatcga tctttttagc ttcttcatag tcaataccgt atatctgagc ataacgtttc 160380 attaatctat catttaattc ttcttgctcg tcttcatcca tacggttatc atcacgacca 160440 gttattgaac cataccaagt accatttttg aaactatatt ctgaagctcc tggacctgat 160500 tcactatttc cttctttatc atcttcatca cttttagaag cagaagaact agatcctcct 160560 ccgccaatag tctctttaat tgtacttgct aaagctttct tacctttact attcggatga 160620 acacctaaac catcattttc aatcatatca gaactggctt tactattcca gtctattact 160680 tttgaatctg aactttcaat agctttatta gttgcttcaa taatatcaga aatatcagat 160740 ccttttctct tttcaggatc tacatacgta ttaacaaagt atacatctgc tttgtcatac 160800 atatcttcta tttctttaac attacctgta gttaatcctc cattagtacc taattgcact 160860 ataattgcat ttttatcttt attgtatttc tttttgttgg attctaatac atttttacca 160920 ttaggcgaag gacctccact tgaataagtt cttgaaggaa ctgcattaat ttgaatttta 160980 ctaactgatt ttcttatttc agaagcagct cctgcaccta tggagtcacc taccataaat 161040 actttattgt aggatttacc tccaccgcct ccaccagtta ccgttttagc tatttttcta 161100 atggcttcag gagtattact gaatggaaat ctatctttaa taaaattatc aactcgtttt 161160 ttaatcttct taatattgta tatatctgaa ttgtaaatct tagttttttc tttttctgcc 161220 ttttcttcag ttttcttctg attattttct aatttattta aaagagctct atcatttctt 161280 acttctttag ctctttgtct tttagcttct ttgacttctt gtgatttata accaccgtct 161340 accattttta cagtaggatc aaatgcagct ccaccttttt tacctttttt agattttcca 161400 gctttactac ctttgtcttc atcactaccg cctttagaac cttttaaagg agctttaatc 161460 caaggtgatg gatctacaga gtttttctcc atagcccaac cgcctggttt acctttattt 161520 atttggaagt gaaggtgacc tgaaccagca gtattagcac cagtgttacc tgagattgct 161580 ataacttgtc caattttaac tttatcgccc tttttaacta attgtttagt taaatgcata 161640 tacgtactat agatgttacc aggtgattta acttgaacaa tattacctcc acccggatcg 161700 gtgtttgatc taataactgt accttctacc atacatttaa ctttttgacc tggaagcata 161760 cctatatcaa taccatagtg ctttcctccg ttaaatgata aaccagaata gttaccatat 161820 ggttgccaaa tcgcagcact tggtattttt ttcatccaag caccaactgt gccatctggt 161880 atttgattaa tagaaccagg tacaattttc ttagtattca tatctacttc gccagcttca 161940 cctgaaactt caggttcacc gtctccacca gaatcgccac cactggaatt tttcatttta 162000 gacattgcaa caaccatttc ttccatttta actaagaaac gactgaacca atctccgatt 162060 tctcctttac catatttaga gaaatcaatt ccgcctttag ctatttgata caaactacct 162120 agaggtgtac tcatgaacat atctttttga atatcttctt cagcttttgg tcctgatttc 162180 attttattat cagtaattgt tttaaacata tctccaccaa ctttagctag tgggaacata 162240 ggagatgctc taaacattag tttagaagta cttaatatta atctacctaa acctgtttga 162300 tcttcagtat gtttttcttc tttactttta gcttcatctt ctattttatc accaggatgt 162360 tcaccaattc cgaagaaact acctaatgtt ttaattggat gttttaatga ttctatagga 162420 tgtttaatag ttttaatgat atcaggagcc cacattgctg caccaattac tggtccaaca 162480 aatggtatga atggtaaggc tgttttcaaa cctgctttta atgcaaattt tcctccagct 162540 ttcattgcac ctttaccaaa taatttattt ttagctttac ctatagcacc aaaagctttt 162600 cctccaagtt tcttagctcc accgaataaa cctttaccga tagatttagc tctgttaaaa 162660 cctttagaag caaatttact tattccttta gttgcagctg aagcattctt tttattaaat 162720 attttagata taccactttt agctactttt cctatagttt taccggcact taatcctttt 162780 ttaactaatc ctgcaccttt acctataacc attttaccta aagatttaac agaaggtaat 162840 ttatctttag caaattttcc aataccttta aatacattac ctattttttt aggagcacct 162900 ttaatacctc taaataattt tcctaatcca aattttccag ctatattttt aattccgcca 162960 cctattttac ctaacatgcc aggcatacta gtaaagaatt tacctattcc gcttggtaat 163020 aatttagata ataatttagg tccaaattta gcagctaaga atcctccagc acccaacatt 163080 gcagcgttac ctaagaatcc tccagcagat gctaagaatc ctttcttacc aggttctaga 163140 tcttttttac catttttacc tttcattaat gaacctaata cagctgcaga agttccagca 163200 aataaaactg gtcccatttt actaaaatca agcataccat tcatcatttt tttagcacca 163260 atggattttt cagcttctcc accttttcca aagtttatat tacctctaat ggattcagca 163320 atttcttttt tattggaacc tgttatttta gacataacat cttccccaga ttttcctgca 163380 tcggcagttg aaaggccttg tttcattctt tctaaagctc cagcatcttg agaatctttc 163440 atatcttttt taatagttgg atcattgcca aaagcagttt taactaaatc gattattgta 163500 ctcttagctt tcttttcttt ttcctctcta gttaaatcat ctatcgtttt gcttggttct 163560 ttagtgtaag catttttatt agcttcatta ttattaattg ataatttatt taaaccagga 163620 atattcttca ttaaatccat taatggatta ttatctataa tactagattg atttatattc 163680 tgataaggat attcatcatc ttgatctggt tgagtatttt cttgagttga attaactcta 163740 ctagatgcag gagaaaccat atctttaata gcacttgtag ggttttcttt gtattcttta 163800 gctttattaa ctgcattaga aagactattt aatttatcca ttacagaagc atgagcttca 163860 ttacttccat tatttccact tagaataggg aaatttttac ctttatctat gatactattg 163920 attgtattaa ctttattatt aataaattct ttattattat taatattatc attactgaaa 163980 ttattgtcta attttctttc tatttctaag aaaatatttt taatttcttc taaatcacta 164040 ttttcccagt taatattacc aaaatcttta atctgattaa tattatcatt attattagat 164100 ctagaataag tcgaattaga tttatttaaa ccttctattt cagtaaatgc cattattctt 164160 gaattatctt ttttatcaag tgtttttgaa atagatttct taatattgaa taaatcagta 164220 ttaaatttag ctgaattctt ttcaaacact tcagataatg actcagtatt aacatttata 164280 tttttctgat taactatttc tttaagttta gaagtttttt ggataggttt gtctatttta 164340 gttaattcag ctaaaacttc tttagttctt tcttcatcat tatctaattt agataataat 164400 tctttaccta aataagtatc tttaaaatta aataaagaat ctgatttaat cttatccaag 164460 tcttttttct tagccgaacc tcgattttcc caaacgcctt ttcggtaatt atagatacta 164520 cctaattcag cattatctgc taatccgcct gaacgacctt cttttttggc tatcaaatta 164580 ccttgaagtc tagataagaa gtctggtata actttattaa tagacgtatg agattccata 164640 tcaaattgaa caggagtatc ttttttacgt ttatttttta gagaaatacc tcctttacca 164700 tcacctaata actcttcttt aaattgatct aatctacctg aaagagcatt tcctaaatta 164760 gatatatact tattatcatt gccagttaat ctttctaaac ctttagtaag tttactatct 164820 tcatcaagat ttctattaat aagcatagaa cctatatttt gtggatcaaa tcttttattc 164880 aatctattaa atatattttt attgtcgcct tcaggatcat aaccaccaat atcaccgtaa 164940 agaagtttat taaatgcaat tttagctcct tgagttgcag caaattcaat aggattttta 165000 gctacaccca tcagcattga tttaagttgg tctccggaca tcatacccat taataaattt 165060 tcaggattag ttttctcatc caaatatttt aataaactaa tattaccatt caatatagaa 165120 tgtaatttac tttgtttatt tcttttggta ttttcttcca ttattgtatt ttgatatata 165180 ccatcttgta ttgtacttaa atttgataaa gctgaatcta cgagactgtt agttgcttgc 165240 attgataaag aataattatt cagtgcaata tttgttccaa caaatcctct ttgatttatc 165300 tcagctaaat tattcattgc tactagaggt gaatttgtta ttttagattt ctttttatct 165360 gataaactaa caatttcaga tttagtccca tcaggattat caatatattc tgttactgat 165420 tcatattcag gtttttcatt agataatttt tcattactac ttgaaaaaag atcattttca 165480 ttagatttat tttttagtgt ttttaataaa tcattagtag aacctttaac ttcagaaaat 165540 ttctttaatc ttctttcatc attgttgaat aattttaaac ctgaatctcc cactatagca 165600 tctaatgatg gattagattt tataaacgca ttaaaaagaa tacgaccagt atttttagaa 165660 gcatttttaa tgacagttga tttattgtta ttttctaatt gtctaatatt ctttttattt 165720 ttattatttt tagccaaact tcaaattcac ccctaacatg attttcttaa tacatatatg 165780 tttctatcag attcatatag attaaattaa aagataaaaa aaaataaaat attcacccta 165840 acacaaataa tccaattaag gactaaatgt gttagggtga attaatatta tttattcttg 165900 actacatctt gtattttatt caatacacta tctaaatttt tagtataaac taaattagta 165960 aataatacat ctaataaaaa tactatcgtt ttatgagtga tataaaataa attattaact 166020 attttatctt gttcttcttc gctaatttct tctttatctt gatgatattt tctgttaggt 166080 aatgaacgtc tacttaatcc catatattca actaaatatt catttaattt cgttttaata 166140 tcatcaagtc tatcataatc actaatactc ttatcgttag ctaaaagaag agttttgtta 166200 taatcgatat tacttgtttg aagaaattta ttgtccatat atttacttaa taatgttgaa 166260 ttgatagata ttaagtaaag aataatatct aataattctt ttgatgcatt attaatatat 166320 tcaaactttt gagaataatt gtattcagga ttattagtaa tttgatttat ttcataatta 166380 aattcatgaa tttcttcaac tatttgaggt atgaatctat ctaccatttg atgtaattcc 166440 tcattaccaa aatcgtaacg agaaattaca tttacatgat ttatatacat agcacttata 166500 tctaattcaa tagattctct tttcttataa aaatgtttca ttgacaattc ctccatgttt 166560 ttaattggtc ttatctaaaa cgttttttgt attcttcttc atatttagca ttgacatctg 166620 aaactttaat atctttacca tcatctgttt taaagttatc tttatcaatt tcttcacctt 166680 taattacttc tttatcttca ttttctactt tagccaccat agcaatatga ggtggtacaa 166740 atgatgcttg tttaactgtt tccattttag cattatgaat acgaccttta attaatttac 166800 gagagaaatg tacatttttc atagttaatg ttttaccttt gactaatgca ttttctctaa 166860 gtgcatcaat ttcattaata atatcactta attctttttt agaatatcta ttatcttcta 166920 gatttgctac taagtcatta ataagttctt ctttagtata agatttctca ctgaattttt 166980 taacattttt ctttctacta gtcattttct ttttaccaac cttctgattt gatttagttt 167040 ttgtactttg tttcttttct tttaatactg ggttcttaac ttcttcttta gtctcttctt 167100 gcttagtttc tactttatct tcttcttgtt tagtttcttt ttgcttaatc tcttttgctt 167160 tctctggatt taaacctgaa gctgttacag ttactttatc ataagaactt tctgttggaa 167220 tatccttaag attaatttca acatctttaa gttcatctga attgatgaaa atttcttttt 167280 tatcataatt aatcttaata acatcatcat cttcaggaat taaaactaaa ttctttctgt 167340 catatttctc tggaatagtt tcgatatcaa atgtaattgt atctccttca tatccttgtt 167400 cttctgataa tttaatctta gctgactcta atacagttaa atcctctttt tcttttgtaa 167460 ctttctttct tgtaattgcc atatccaaat ctctccttat ataaaataat ttgaagctaa 167520 tattcttact aacttcatta aaataatata tatttatatt attaattgaa gtttataaat 167580 ttttattatt agagtttttc tatgatccag agtattaata tattttatta attaaaaata 167640 tatttattaa taatatttat attaatatta attattaaat ttataattac ttactaatat 167700 aagtaatata ttaatacaaa attttaaaaa tttataaata aaaattttat aaaatctgaa 167760 taaccaattt atattaatta aaaaatcaat gacgtttaaa aatataataa atttgattga 167820 ggtgtattaa gataatgggt ttaaataaaa aacaagaaga aggattaaga ttagctaaag 167880 aatggtataa taatgatagt catagacctt ttgtattatc aggtattgct ggaagtggga 167940 agtcatttac aatgactaaa ataattgatt ctttaggctt acatgaagct aatgtttctt 168000 ttatagcata tacaggaatg gctgcaggcg tattagttaa aagaggtttg aacgctacta 168060 caatccatag aactatttat aatcatttta tggatgaaaa aactggtaaa gtgaatttta 168120 gattaaaaga tgaattaccg agagatatta aattaataat tatagacgaa gtttcaatgg 168180 ttcctatgaa gatgatagaa gaaattcaaa gttttggaat acctatacta tgtttaggag 168240 atccagcaca acttaaaagt ttatcaggaa gaaatgaatt attagataaa cctgatatat 168300 ttttagatga accagtaaga caatcattag ataatcctat acttgttgca gctaatttag 168360 ttcgtaatgg taaagattta gaatatggtt catatggaga taatgtacat gtaattactt 168420 cagatgaatt gactttagat atgtatcaga atgctgacca agttctaatg agttataata 168480 gaacagtgga tcaatttaat agattctata gaagtcaaat attaaatatt gatgttgaaa 168540 ataatccatt tcctaaagaa gatgaaaaaa ttatttgtct aaaaaataat tggtctaaag 168600 tagttaatga aggtaatata actcagtatt tgactaatgg tctgattggt aatataacta 168660 gatctggtaa aaagaaacct atgactaaat caactcagtt ggattttaaa cctaaaggtt 168720 ttgaaatgga aagatttagt agaatatatt acgatgattt aatctttgaa ggaactattg 168780 gagatcaaca agaactattt gatttaagat tcaaagataa tgaaattaat aaaatattta 168840 agaaacgata tgtaactgaa atgtctgatt ttggtatgaa agtaaatcca tttaattttg 168900 catacggaat tactattcat aaatctcaag gttctgaatt tgataatgta atagtattta 168960 gtgaaaatat gagtaaagat agatttaagt cgttatatac agctattact cgtgctaaaa 169020 agaatttgat tgtagttcaa taatatgtat aaggatgata caagtggata ataataatgt 169080 aagtagtaaa atcaataaaa atcaattaca aacagcaatg aataatatgt ctaaaaatat 169140 aaatggtata ggtagaaagc tatcaggaca agataaaatt gatgagatta ataaacttaa 169200 aagagaaaat gaagaattac atcgttttct ctttaagatc tatcaagatg atgattttga 169260 tagaagagaa ttgaagaaaa ttatatttaa agatgtaaat aaaaaattta aataagggtg 169320 attaatttga attcagatat ccgaatagat agaagtggtc tttatataca atctaatgag 169380 aagcagatga agggacaaat taaaattata gaagaaaaca aaaaattaaa agattttatt 169440 attggtatta aaaataatgg tggttatgat gaaaaggaat taaataaaat agtaaatgaa 169500 attgttaagg agaatttaaa ataatgtcaa atgaaaaagt tattgctaaa gaattaacgt 169560 tagaccagaa aattaaaatg ttagaaccaa agatagatga agagacttat ttaagaccat 169620 taagtcaagt agatgaatct ttttataatg aggttattaa agatgaatta attgagaaaa 169680 ttaataatga agaccataaa tttgaaaata attttgatta tcatatattt aaaaacggac 169740 caatacaatt actaggtttc atttataaat ttgaatttaa tgaaaatgca gtaaacgtta 169800 aaaaagaaaa acctaatgaa ggtaatatct attttggaag ctttatatta aataataaaa 169860 ataaaaaaga tgattcaata tatttactta gagttgatag cagcttagtt gatttcagta 169920 tattagaaaa taaaaaatat aaagaatttg gcagaaactt atttaaatta attaaatagg 169980 agtgatataa atggataaag aaatcgaaga tctagcagga aaaataaata atctagaaat 170040 tgaccttaaa gggataaatt acagattatc taatgataaa caagttattg attttgaaat 170100 aaataaaatt aatgaatata ttaaattttt acatgaagaa aatcaaagca tcaaaaaaga 170160 aaatatgttg ttaaaagaag caatagtgtc tatttctaaa catacagaat ttaagaatga 170220 ttatataaat aaactgtcta aagaaattgt taaagaaaat tttaaataat aaagagatgt 170280 gattttattt tgaataatga aaaaagttta attaagcgta tggaagagtt agaagaacgt 170340 actagaatga atgaaattaa attaaatact atgaaagata attatcatta tataaatgat 170400 atcataggca cattaattaa tagaatagaa aattctaatc aaactaatga aaagaaattg 170460 gatgaagtaa gattagagtt agttcgtctt tctaacgaat taaattcaca ttctgaagta 170520 actaaaaagt atctaaagaa ttttatcaga gataatctta aataaaggaa tgaagtgcat 170580 gaagactatt aaaagaataa ttggctcaga agaatttatc aatacggtaa agaaaactat 170640 agctagaact aagaaagcag aagagaaatt ttatgattta aataatagag ttgataaagc 170700 tttatcttta gctagtagag ttgttgaaga taataaagaa aaagaaagac aaattaaaga 170760 gctaaaagaa gctttatcta aagaaaaaat taataacaga agcataaaat cccgatataa 170820 tagattatta tataaaaatg gagggaaata ataattatga actcaaatat taattttaat 170880 gataatggat catctatgga tgaactatat tcaagaatgc aacttagagc cgctaaacaa 170940 gtagaaaaag atatattggg agatactgaa aaagattccc tagaaaaaga attaaaagaa 171000 cttagagaac ttgttcttga agtagctaaa aagtatgatg ttaaagaaat aaaagaatat 171060 ctagttagaa aaaatatgaa atagtgttta agaaaagagt tgaataaaat tggttgaaaa 171120 tgatttagat atctttaaag caattgaaaa agcaactaat aatatcttag ataaaaatga 171180 aaaactaaaa agtgagaatt tagaacttaa agaattgata ttagatattt ctaaagaata 171240 taatataaaa gataaaagaa taactgaaat aaaagttgat ctagcaaaaa ataagaggta 171300 atgacaaatt aatgtcatta cctcaattat actgctttta gtcatcatat ttatctttat 171360 attcataata actatcaaat tgaacttcta aacctgagaa agctgaaatg aatcccattc 171420 taccttccat attgatgttt tcaatatctt taaaatcaac atctggttta cgataattga 171480 aattcttatt tttatctata aatattctaa ttctattttc atttttaata atcttaatat 171540 acttgttatt aatgtctaat ggaacatgat tagttaaaaa taattgtttt tctgattcat 171600 cttggaatat ttctttaggt tttccaaata ctttatcaat ttcatagaaa ccagttttca 171660 ttatacggtc aggatctttc ataacatctt catcattcaa atcaaagtaa ggaacatccc 171720 aattttcttg ttgagaagct atccaaagca tataacctga atttagttga gtattataat 171780 caaatataat ccctgctcca ccagttttat ttttattaat tactttaaat gtcataatat 171840 aatttttagg gaatttgaaa ttttgactat acacatagtt caatgcgtca tcatcaaatt 171900 tagttgttcc atctatgaaa ctaatataac cataattacc taatgattgt ttagataaag 171960 ttttattata aaatccggta taagtttgag tttctacagg aaatgtacca tatgatctta 172020 atgcaactat cataggatta aagtatattc ctgatctact ctcatcatag aaataatcag 172080 aaccatctgg atttttaagt gaataattat actccaactc aacattatac caatcttctt 172140 tagttacgat aaatgtatta tcgaattctt catgactaat tccagctatt tcaaattcat 172200 ctaaactaac ttgaattatt tcatttggat caacgtcatc aacaaaattt gttaatttga 172260 cttctatttc cattttctta atatttttca tattgtacat catatgttta agatatgatt 172320 tttgaccttg agtattataa tttttattat ttgaagggaa tatattttct acttttttaa 172380 ctttacctgt atttgatgtt aatgtgatat cataaactaa cttagctgta ggatgattat 172440 tatctttaaa gttagttgaa tatcccatat taaacgcaaa gaaatcataa tttaataaac 172500 gtttaatatt cattctagga ttttcatttt catcatctaa agttatctta acaaatgatg 172560 cagaattttc atcttctttg tcagatttac ttaaaatatc tcctttaact tcatataaac 172620 cggtttcttg attaaaactt actgaagata atcttgttga ttcaagatta gaatgactta 172680 catcttcatc attagctttt cttaaatcaa atatagctgt gggtgcttta aattgatagt 172740 tctctgtagc attaattaca ttaaaacctt ttcggtctgt tatttttaat ttagatgtac 172800 cattttgtaa aggtgcaaat aaatatttct ctcctggttt aaagtacatt ttaccttgaa 172860 atttacgtga aaaccctttt ttataaaata gatgtggtag agtttttaaa ccatcgttat 172920 taagtgtaaa tggttctact aaatctttat tatctgtatc aggtctatag aatttttgct 172980 catgaacttc atgtctttct cttagatatc tatcagaagt gatattttct aatttatctt 173040 caaaatcagt ttcaggtacg aatggtataa ttctaggatc attatatcct ggtgtaactc 173100 taccggattt ttcttcagta cttttcatca tatgtttaaa aataggttta ggattatttt 173160 cagtacctaa tatttcattt tcttcattaa taatcttatt taaatcatta atgacagtct 173220 ctgggaaaat ttttacagta tctgtattaa attgatccac tgtttgcata tcattaacaa 173280 aaagtaaaag ataccaaaga tcagtagttc catataattc attagataga tattcaggtc 173340 gatagtgata tgattttgat aagtcataat ctattaaatc tcttttaagt acattttcat 173400 atttttttag taatggtaaa ctaaagacag cttgtttttc aaataaatac cattctgata 173460 tattattaag taatatttta ttcgtcttgg agtattctat ttcatcagac atttcaggta 173520 catcatttct acccatattg ttatttccta cgtcacgaat aagcaaaatt atttcacttc 173580 cattcttatt ttgttataat aaatgcatgt taaagttcga atgagcatat taataaaaaa 173640 ctaaaaattt caactaatat tttaaatata tattatttta atgagattga gatggaatta 173700 atcttaatac tcaaaaaata aaaattttta attacaagga gagatttgga tatggcaaaa 173760 gtaaaatact cacaaacaaa attattggta agaggagcat ttagatcaga tgaaattatc 173820 aacgtagttg gtgatggcgg aattggtaaa acacaaatga tgagagatat tgcagaagaa 173880 gataatatga acttcattac tatcgctgca aataacctta aagaagggga attatcttta 173940 ccaatgttat cacaaaaaga taatgaagtt atctatgctc caatggataa aattaagtta 174000 gctaatagtc tttttgagag atataaagag tatcaaagag aaggtggaaa acaatattca 174060 cgtaaagacc tttctttaaa atctgttgat gaattaaaag aaatttatgt gaaattgact 174120 ggtaaagatg ttgttgatta ttatgaggat actcatgaaa actatgttaa taaagtattt 174180 aacaaagcta gagttaaaaa tgttaaatat agtaaaaatg atttaatgaa aaaatcattt 174240 gatgaattaa atgaaatctt tgtagaatta actggtaaag aattaagaga taaaattggt 174300 aaaggtttct atatcaaaga aattttagaa gcagttccaa gaccttatac tctattattt 174360 attgacgaaa ttggacgtac agaccaacaa gtacaatcag agttaatgaa cttcttatta 174420 gaacgtcaag taaatggtta tcatttacca cctaacgtta agattgcatt agcacaaaac 174480 ccatcttcag acatgccagg atttgaagac tcagaatacg cagcaacttc tatggataac 174540 gcagtaagtt ctcgtattac atttgtacac atggttcctg atattgaaag ttgggtagac 174600 tttgctacta aatataaaga tggttcagaa aagcaaaata ttcatccatc tattgttgag 174660 ttcgtaactg aaaaagaaag tactgaatat ttattcagac ctcataaaga agctggtaaa 174720 gacttcaatg atactaaccc acgttcttgg gaaatgattt ctaatatgtt atatgtatta 174780 gaagaagatg atttatttaa attctctaat agtgaagaag agaaacgtaa gaagaaagat 174840 actttacaat tcttcactga aggtaaaatt aatagtgatt tagcaaactt atttgttaaa 174900 ttctatattg aaaaacaagc taaattacct cgtccaagtg atattttatt tgaatatgat 174960 aaaggtaaaa tggttcctcg taaagaatta gctaaacaac acattgaagc tattgaaagt 175020 caatcaacta ttagacaatt aacattgaaa acttcaatga ttaactatct taaaaataat 175080 cctgatttag ctgaagaaca agttattcaa attgctgtag aagctttatt attaggtaaa 175140 gttgaaacta atgctacacc aattagatta atttctagac tttcagaatc tactgaagag 175200 tcagaccaag aattatatga gaaattcact gataatgaat tatacagtga taaagcattt 175260 gcattatacg aacaaatggt aggaagctta ggataacaat tatagataat ggagattatt 175320 agtctccatt atcttcattt atttttttat aattaggaga gtgaatttga taatgaatga 175380 taatagaaca attaaagtaa ttagaaaaga aatattagac gaagtacaag aatcgattgt 175440 aaatgataga cagttagata aaaagaaatt aacaaagctt ggagaagaat taattgaaaa 175500 tagtattttt gtgttgtata cttctgatgt tgatatttat ggagtaatgt taatgactgt 175560 agaaaagatc attgacattg aaattccaga accaactttc tcagtatttg atgaagaaaa 175620 aggttataag attggtatta atccagtgtt attagccact atggttgata aagatgaaga 175680 aatagtttct atgttcctac atgaagttat ccatgtagct catggacatt taattgaatt 175740 tagaatgtta agaaataaag aagattctca attaaaaatg ttaagtcact taggaatgga 175800 tttatcagta tttgaaattg aagaagactt ccaattaggt aaacgtgaag ctaatacaag 175860 taaaaaagtt ttacctgaaa ttgcacctaa tgtagataag attgaaaagt atattcaaga 175920 taaatttaat aaaacaaatt ttaaattaaa tcataatgat gcttctcact attatattaa 175980 acaattagta gatatctaca aagaaaataa tgaagaagat atgtttgatt ctatgggtga 176040 atctatgcaa aatatgattc aagaatcttc agaaaaacag aatgaacgtg atgaagattc 176100 attgaatgaa gaaaatgaaa tgttgaaaga catgttagaa gatttaaaag acattgaaga 176160 taaaaatgat ttatctagta aattagaaga taataaacta gaagaaaaca aagttgatga 176220 ttttgaaaat aaagctcaag attatatgaa taaattagat gaaatgaatc aaaatgatga 176280 agagaatagt aatgatactc aaaatcagaa aaatatagaa gagaaaatga atgatttact 176340 agattcaatg agaaataata cttcagataa taaatttaat agtaaagata ataatgattt 176400 atctgataaa atacaagaaa tgaaatcaga tatattaaat caaatgattc agaataatat 176460 gcaacagggt tctcaaggta tgcaaggtga agatagtgga atgcaagatg gacaaaatgt 176520 ttctgatatg ggaagtaaca tgactatgtc atcttcttta gatggaaatt ctaaatatgc 176580 agataaattt gattccaatc ctcttgaagg agatgctaca gaggaaagaa tgaaagacca 176640 attgtatgat ttattagaaa gtgctagtag taatagtcgt ggtgatacac ctaatcatat 176700 taaagaacaa attgaaattc taaaacgtaa acctaagatt aaatggcaag attatcttaa 176760 agctaaagta ggtaaaaaac gttcttctag tacgaaaact attttaagaa gaaatagaag 176820 acaaccttat cgtagtgatg tacgtggaac tttacctggt agaaaattag gtaaagtatt 176880 tgcggctatt gacacttcag gttcaatggg tagaaatgaa attgaagaaa ttattgctga 176940 attgtattat attagtagtg atatgaaaat tgatttagtt ttattattct tctcaactgg 177000 tgttgaagaa gtagttgaag taaacagacc aaatcaattt aatgattatg taatgggtcg 177060 tggcggaact tacttcagtt ctgtatttga tttcttaaat gaaactgata acaaacgtaa 177120 atattcagta tcaaaagatg atacgctatt attcttctca gatggttttg gagaacctga 177180 ggtggaatac ggtgtattaa ctgatgttgt ttgggttatt actgaagatg aaaataatct 177240 ttcagttaga gatccaaaag gtaaagtact aaaattagaa atagataata aaagataatt 177300 caaattacgt caatggatat taatttatcc attgacgttt atatttaaaa ttttttactt 177360 aaaggagatt aaacaatgtt aaaaaagact acagaaaatg aattagaaaa gttattcaat 177420 gtcactattt ataatgaaga attttctaat ttaaaaccta tgtataatag aaaagatact 177480 gaaactagaa ctaaattaaa tgacaatcaa aattctagag tgtatgagaa tttaataaat 177540 ttcattaatt attctaaagc aggaatgaca cacatgtttt taactcgttc taataaatat 177600 agagataaat atattgattt tctaagaaat agacttggta aggaagattt attagatgag 177660 gttgaatttg aatatacaga tagatatttc agatctttca tatataatat agatataatt 177720 agaagaagtg aatatcaaac acatcaatct atagaaaatg actctaaatt agaagattca 177780 ttcttattaa gaaatggaaa tacaaatata gatagcttta aaacggataa tggtttatct 177840 atagaatttt tagataaaga tgtaaagaaa gattttttag ataagaacaa acaaattagt 177900 ttagaatctt tgctagctat cgatacgatg gtgtctaatt cattaagaaa gaaatggtta 177960 aaatcaattg aaaaagaaga attacctgat atgaatatta tatttaaaga agttccagaa 178020 gtagtaatta tactagcaaa cagtatatat gaaagatcaa atttcaaatt atcatatgta 178080 gatagaagtg ttattaatat acacgcagac gtttcagatg ttttggaatc aatactaact 178140 ttaacttcta attttaatta taaattaata ttagatttaa tagatgaaga ttacttaagt 178200 aaaaatttaa atcatttcaa agcttctgaa ttttctttat ctgacaataa tgacattgat 178260 aatatattta gtataatcgg aattattaaa aaacaaacgg acgttattaa taaatttata 178320 gaaaaaagca aatcagataa tctagaagac aatattaatt taataattaa agaaaatgaa 178380 atagatgatg actttggaga aatattaaaa gtttatattg atagtgtatt atctaaattt 178440 agagaatata ttgaagatga taccaatata ttaaaagatt catctaaggt tttaataggt 178500 gaaaatctat ttggtttctt tatgaaatta gatgatctcg aaattttaat gattagaaat 178560 atatacagag ttttagatag taatgtatat aatcctgtaa tcagagatgt taaagaatca 178620 caagaaaaag ttatgaatgg aatagtagat tattttaaaa ataatactaa aaaattatct 178680 ttagatttat ctaatatcga tataagtaga ttgaaagata gttctttcac attattaaac 178740 gatttcataa caaatggaga agtaagtaat cttcgtatga aacctaatga agctaatata 178800 gagtatttct ataaattaag tgtggataaa gaattaaacc gtgacatatt aaatagtaat 178860 atacaatata tgaaacagga attattaaaa ggttttaatg atgattctaa aatgacttcg 178920 aatgctatta ttgaatttga taattttaat attaattttg ctgtaataga aaataattca 178980 tataataatg aaatagaaat aatgatgcaa ggagttactt ttaagaaaaa attaactgat 179040 gaggatattg ctactatctt tttatattca cataaagaag ttagtatata tcaagacaaa 179100 aaattagtta tcatggatag aaattatttc tctagaagag gtataaataa atttataaat 179160 aatatgaata atgtcttcac tgatttagat ggagaaagtt tatctaaata tatgtcttta 179220 atttataatt tattatcttt atcagataat tcttttgagg aagataaagc aatttataat 179280 actctatatt acaataaatt tgaatatatt aataaagaaa atgagttaaa agttgatagt 179340 tatattaata tgattaataa taaagatgta acagatgatt ttaaaaagaa atttaaaaag 179400 gtaagatcta agtatttagt ttctagaata tttatttaaa tatatattat ataattgagt 179460 tgataattga acttatcaac tcaatttaat ttttaattaa taggagatga aatggatatg 179520 agtaaagcaa taaaagattt atttatcaat tacaatatat cttatattga agttaatgaa 179580 gatcatgaac ttaatgaaat tgataaagaa gaattattaa aaatattaga ttttgatatt 179640 aaatttgaaa aggaagaaat tttaataagt gataatatta aaataaataa ttttaacggt 179700 aataagttaa taaattttgt atttaattat tactatacag ataatgaatc actaaaagta 179760 tttttaaaag acgttatcaa agatattatt atgtatggat ataaagaaga tagaaaaata 179820 agtctaaata taaatcaatt acctttagta ttttatataa ataaattttg taaagataat 179880 gacattaaaa atattaaatt cttttatact tttaaaaatt cttatgggaa tttttcattt 179940 ggtttattaa aagaagaaca tctagatgaa tttattgatg atatagaaga aataagcaat 180000 aataagttct tcaatttaaa tagagaattt ttagatacta aattattgat taatggagat 180060 aaaaagaaat ttatgaagct aatatctagt ttaatagatt tggatatgtc gcataagagt 180120 aatatattta aattaacaat gataaattat ttttataaat tattcaatat tcatattaat 180180 agtaaagaag atttagagta tgcagatgaa ttaatgaagt ctaaaataga tagcgttaaa 180240 tatgatgaat ttaataaata ctatatattt gaaagatcca taattggtat agatacatta 180300 tatgaaaatg aactcctagg atacaataca agaataaacc ataattattt tactgataaa 180360 atacaaaaag ttgaggatga agataaagtt aaacatcttt caaaaatcag tttctttaaa 180420 tcaatagatg acatttataa agaagcatta ttcttgttat cctttgaaac agccaatgaa 180480 tatacagaca ttgcagttaa agaagtatta agattaattg aaaataattt tacagaaaat 180540 cagaaaaaac aatttgttaa agcatatatg agtatcaaag atagttcatt taacgtttca 180600 aatgataaat ataatcaaac atctacactt gttaaaatgt ctaaaggaaa attaaagaaa 180660 ttaattatga atgaaacagt taaaaagaca tttatttaaa ggagaatccg cttatgttag 180720 ttaaagaaga aaaattaaaa aatagaaatg atattagaat agaccatatt ataagtatta 180780 atttagatga tccttctgca cttaatatgg tttcatttca attattaata gaaagtaata 180840 ttctgagttg ttatattaat aacaacttgg atactacttt atttactaaa aaagaattag 180900 ataaatataa taaattcata gattttgcta ttgataattt tgaatcaaat ggattattta 180960 taaataaaaa accggatgaa tttctaactg gtttaataag aaaagcttct atttctagat 181020 tatttaaaat gattgatcca attgataaaa ctatcagtaa tgaaaattta tttatcacta 181080 gattaaaaaa tattagacat aatataaatg aaacagatag taaagattta gcttatttct 181140 tatacaccaa ctttagagaa gatgttccgt tagatagatt aaaaggttta atgtccaatc 181200 cacatttaac atcattattt gagtatttaa tgaatggcaa tttaataatg gagattgacg 181260 agcaattatt aaataaatgg attatgttta ttgattatga aatagatgat attaaaggac 181320 ctatttatca tagattaaga catagtttag ttaatgtaat taataagtat aataatatac 181380 aagaagctaa aggttattta gggtatgaaa gattagaatt agaataaact taaaaagttt 181440 agtgagaagg gaaattttga atgaaaaaat ttagagatga attaataaat cactatacaa 181500 atttattgag attcaacgat gattcttttt attatagatt aaaaattaat tatttgaatt 181560 tcgatttctc taaagatgta aatttaagaa aaaataatgt gtttaaatta aattataaaa 181620 tcagcttttt cctatatttt aaaattttaa taaaagattt tatttcaaat aatttagatg 181680 aaaatggtgt atcattatta ttttcagata gtgttaataa taataatttt atttctacat 181740 tatttgttaa aaataattct gatattgaat tgaaactaga tttgggtgcg tattatgaac 181800 tagatgaaac taaaatagtt ctaatagatt taaatgaaga gtttaatata gaatattcag 181860 atgatagtat tataattcat acagatgaag ataattttga aaatgtagtt tattctattc 181920 taaacaaaat caaattcgtc ttagaaggaa atatatatgc atttagcata tctttatttg 181980 gcaatggaaa aataggagat agtaatatat tttatttaga agagattgaa aatatattta 182040 actctagaaa aaatagtata attgaagagc tttctgaaag tgaagttaaa aaatataaaa 182100 tcaaagaagg gttcaaatag taatgggtga tattaaattt aatgaagaat atatgtcagt 182160 taaaatttat aagttaatta atttgtttga gtttcaacaa acaactcgta aaagagcatt 182220 ttcaaaccat aattctgaaa gtgatgaaaa tgagcttaat atgtatatag gtaaaaatga 182280 caataaaaat atgattgaca tttttactag ttctttcttt ttatacaatc aatttaaaga 182340 tgtttgcagt ttagtattta acaatggtaa tactattatt gcagaaattg agatattaaa 182400 taaaaataaa ttgtcaattg aaattaattc agaaatctta attgttgata gtgaaattaa 182460 aaatttcatt atcaaaaatg attttagtgt aggagatggc ttcttaggct taattattga 182520 aaatgataaa gaaaaaattc ttaaattatt tttagaatca ttgtctgata gttatttttg 182580 gataaacaag aaaagaagtt taaatatatc tgattctaaa aaaattaaat ttaaaaaata 182640 tttagaagat ttatataaaa tgaaagattt ttatagtaaa gaaatcactg aaaaagaata 182700 taaagaaaat atagtaaaag ataatttcaa ataatataat cccaatactt attaatgtaa 182760 ttaacaaatt taaaagatta aagattattt agattacgaa agattagaac tggagtgata 182820 ttttaatgga agagatttat cttgataaaa gatttgatag tgaatatttt aaaataaaaa 182880 ctagagatat gataaactct gtaaaattta ctaaagaacc aaactttgat ttaattataa 182940 ataaccgtaa agaagaaaaa attttatata ctaaaaatga cagtattaga aatctattta 183000 ttgaatcttt tatcttgtat ttaaataata ttacagacgt ttatacattt agtatatcaa 183060 tcagtaatat taagttaatt tttagtttaa gatacaatca tacgaataaa gataccaaat 183120 ttttaattta tataatagaa aatgataaat ttaattatga aaaagatgta tctgaattag 183180 aaaaaatatt aaatgacata tcttctttag taaataaaga atactatata tctaaaggta 183240 gttttataat agactattta gatatagaaa aaattgataa gatattgtat tacattaata 183300 aattagatga tcttcgtata atgttagatg attcagaaaa agaaggaaaa tcgtatttaa 183360 gttacaactc ttttcttaaa gaactttatt taaaaagaaa cttatattct aaaagtatta 183420 ctaaaaagga atatactgat aatttagtta aagaaaattt taaataatat aatcccaata 183480 cctattacat caataggtat tgggataaat ttaaattatt ttttatttca tgctgtctaa 183540 ttcagctaat tttaatttag ctttagttgc atatttttga cgaattatgt cacgccattt 183600 tttacgagca cgagcagctt tttgatattt aaagtaaatt ggatcttgag cttctttagc 183660 tgcaactaat gctaattggt ttaatctacg tttacgttta gtacgttcat ctaaacgcat 183720 gatattttgt tcacgtaaaa gagcttcatc agttgcttgc ataatttgct cttctagtgg 183780 agtaatgtta tttttcataa tggaagatct tcctttcaat tatttttatt attcattata 183840 atgattataa gaaatatgtt ttatttaaga aatatgaaaa aattattgaa ccataataac 183900 ttatcttata taagtatgaa tctataagga gatgagaatt tatttatgtc taatcaagat 183960 aataaatatg aacgtaaaag agctataaca ggatatttag aaaatttaat caaattaatt 184020 aaaataagaa aacctgatat tgataatgaa aagttaatta atacttgtag agagtatatt 184080 aaaaaacatg tagatccagc tttaatagaa atatctggac aaaaaatgaa tgtggataca 184140 actttaagac aaattataga taataattta attgtaactg gttctggttc tatttatcag 184200 cctcaatcac aaagaaaaaa tttaaatgca gacatgttaa aagactttat agattctcgt 184260 aaagtagcta aacataatat gtttatatat aaaggtaaag atgatgtttt acatgataaa 184320 tatatgaacg aacaaaaaac aattaagatc ttggctaaca gttattacgg tgctatgatt 184380 caaaagaata gtacattcta tgatgctaat tcaggtccag caactactta tagcggtgtt 184440 gatattgtaa ctacttcagc aatagcttta gaaagattta taggtggaaa aatattcttt 184500 atgaaaattg atgaaatata tcattatata ttaagaataa ttaatgaaaa atatgaagat 184560 catgatatta agataaaatc aattccgact gataaagaaa ttttagaagg tttagtttct 184620 aatgttgaag aagattatag tgaagaagaa tatcttaaat tagaagaagt atttagtaaa 184680 ttaagtcaag aagataaaaa taaggtatat ttcaaaaata acttatttgg tttaattgat 184740 catactgata tatttgagaa taaaattagt aaaatgactg gtagagaaga tttcttagat 184800 ccaaacgaac cacctgaaga tatgattcca ttattagatg aattatttga aatattaaaa 184860 gattgggtta tatacaacta tcaagattat aatagaatgt atagaatgaa ttacaagaaa 184920 cgtagaagtg ttctcacaat tgacacagat tcaaatttcg tacacttaga tccattatac 184980 gaaaaaatga aatcattaaa acctgaagat tttcctctag cagaaaatgg tttagaagat 185040 aaattagaag aacgtgtagg taatatatct attattaact atcaaataac taagttatta 185100 gaattatctt actatggatt ctgtaaggat gtaggattag aagaagaaca tttaggctta 185160 atatcaatga aaaatgaatt tttacttgat aaacaattaa caacagataa aaagaaaact 185220 tatgcatcat cagtaattca acaagaaggt aatttaattc aacctccaga tttagatgtt 185280 aaaggtatgg ctattagaaa agttaatact aataaacgta ttagagaatt atttactgaa 185340 atattacaaa aagatatttt agaaaataaa actggtgtag atcgtattaa gataatacgt 185400 aaatttaaag atattgaaga aatgattaag aaatcattag ataatggaga aatcgaattc 185460 ttaaaaccat ttaaagctaa taatgctgaa gtttataaag atccttattc tcaaatggct 185520 tatagagctg ctttagcatg gaatataatg ttcccagaaa aggaaatagc actacctgct 185580 aagatattag cagttaaatt aaatattagt acatttggtg atattaagaa taaaataact 185640 gatgaagata ctttaaatag atttagagaa gtatttaaga atgaaagttt agttaaaaat 185700 ggtttaaatg taattgcagt cgaaggtaat acaattcctg aagagtttag accttttatt 185760 gactatgata gtatgattga agatcatatt aaaccaggta aagatattat tgaatctata 185820 ggagttagag tattggaatc ttcaaatagc tcatctgtat ctaatatgat taaattctaa 185880 ataattgaat gaggtattta ttatggaaaa atactataaa tttaatttat ttgagtacat 185940 actgaaaaat attggtatgc attcagatga atatgaaaat ttgataagta atataaataa 186000 aaattttaca tctttatatt tttatgacta tgagattaat aatagtgata tagataaatt 186060 gatatatgat aatattcaaa aacaattaat tgatgatagc tattttttat ttgaaatcaa 186120 taaagaagaa agattattag ttgattttga aaataacttt ttatatgata aatataatga 186180 gaaaatagga atggtttctt taaatagaat tacttctttt gagaataaat atagagattt 186240 aatatttatg gaaaaagaag atataaaata tgaaaattta attgatatgg ggtttaatat 186300 tgtacctact tttgaaattt ctactgtatg taaaaataaa ataaataatt ttagttactt 186360 tggttttgat attaaagata ataaaaataa gctattaatt gaatgtgatg aaaaagaatt 186420 caagataaat aaagttaaga ataattttat ataaatatta aaataaattt aataaggatt 186480 atgaataagg agactttgaa ttttatgtat aaagaagatg aaatgaatac aggtcatata 186540 gttgctgatt gtgatgaagt tttagtaaat atttccccta agatagttca gttaatgcat 186600 gaagattttg attattacaa tcaattcttc agactatctc cagagtataa ttacagtact 186660 cattacaata cagttcttaa tcgtcctgaa tattatattg accaatggtt agtaagaaaa 186720 gatgtttatg aaagattttc tgaagatgaa gttaatgaag ctagaaatag gttacaaaat 186780 gaaattatat ttaaaaaaga tttatacgat acattagaac caacaaattt agctaaaagt 186840 ttatcatata caatcaatac acctttaatg aatagattat caattgtaac taaaacttct 186900 gataataact taaaatctaa agagaaattt ttgaaaactt tatttagagg aagtatggaa 186960 aaggttgata tttattatct tgaatcagat gaaaagaaat cagatgtaat taatacatta 187020 ggttatgtta ctagaatata tgaggatgaa gttagtaata ttaaagacat tattatgaat 187080 tgtgataatg ttatgcaaac tggtatcgat attccttcat taggatataa ccaaaaatta 187140 gatgaagcaa ctattatgaa agctaaagaa aaagaaatag acttaaatta ttttagttat 187200 atgagtaata gtttagttaa ttaataatta ttgccatgtt aagtttatag cttaacatgg 187260 cttttatata tttatttttt ttttataaaa taagattgga agtgaaatgt tagatgaaaa 187320 tagatatgat caacgttgat caaattatta cagcctatga agctaaagaa gttaccaatc 187380 ctattttctt tgattcagga actttaccta aagaagacgg tttattctca tatgaaatat 187440 ttggtttaat aggtactgat gaaagaaaga acaatgtggg gtggattaat ttaggtggta 187500 aatacttaaa tcctgtagcg tataaagcta tgaaagaatt agataagaat atagatttat 187560 gtattcaagg atctgattac tttaaaattg aaaaaggaca attagttcca gatgaaaatg 187620 gtgaaactgg attaaatttc ctatacgata attatgaaaa tcttaaattt agaaaaaatg 187680 attctcgtat ccgaaatgaa aaaattgata tgcttaaaaa tactcctaaa gatagaatat 187740 ttacagataa atggcttgta atacctgctt tctatcgtga ctttaaccct aatgaaactt 187800 caggagaaat tcaagatact gaagaaataa atgatatgta tgcgagtatt ttaagatctg 187860 tagattcaat tagttttaac tcatttgatt ttgtagctaa tacgactaaa tataatattc 187920 aaaataaatt atttgaaata tacgttaaat taacttcagg tgaactatca ggtaaaactg 187980 gtatgatgca aagaaatatt ttaggtaaga cagtagataa tagtactcgt tcagttattt 188040 catcacctaa aatcaattca aataaatgga atgaaatgca aattgaattc ggtcaattag 188100 gtgttccatt aactcaatta gtaacattgt tcttaccttt ctttagtaaa tatattatag 188160 actttattga aattcataaa gatgctttcc aaactgctac tggaactgat gaaaaggaat 188220 taacattaga agaagtatat gaacaatttg atgataaatc tattaagaat atgttagaat 188280 actttattaa agaccctaat gaaagattta gtcctatata tgtaaatgat agacaaggta 188340 aacgtcataa agttaaatta tttgaaaata ctttaggtag aacttttact gtaattgatt 188400 tactttatat agctgctaca gaaatatgtg aagataagta tgtggtttat tcaagatatc 188460 cgattgaaaa tttcttgaat gtggctcctg ctaaaattaa aatactaact acagttgata 188520 caattccaga aattacttta gatgatattg tacttaaaga ttatcctaaa gttgttcatg 188580 aatatcctgt tgatgaagat gtatttatag atactgctat tatacacaac agttatgctg 188640 gagcacttgg agcagacttt gatggtgaca tgatctctat aagatctcta tggacagtag 188700 aagctaataa agaagctaat aaacttctta ataagaaaac taactatcta aactacactg 188760 gtaattcagt acgtaattta ggtaatgaat cagttcaagc tttatattct ttaactaaag 188820 aataactata tattataatt atagtatata ggaggttatt tttatgaatg atagaacaaa 188880 gaaatttaaa gaaaaattag cagaaagaca tccagataga tatgaattac tgtctgaata 188940 tgagggttct aactccctta tcaaatacaa atgtttgaga tgtaataata tttatacaag 189000 acatgctgga aatatataca aaaagaatgc taaatgtaaa ggatgtcatg tcaaaaaata 189060 tgatactgaa tggtttaaag aaaaattatt taaaaaaatg gatattaatg aatattcttt 189120 gttatctgaa tataaagata caaaggaaaa agtaaaaatg aaacacaata aatgtggtaa 189180 aatatttgaa gctacaccta atagactatt atctggagac aaatgtcctc attgtgctgg 189240 taatattaaa aaaaccatag atgacatatt tgaaaatttt aaaagtaaaa tgaataatgg 189300 tgatgattat gagttaatta aagatgatct atataatgaa tatgctaata tagattcatt 189360 tgtccacata agacataaaa aatgtaataa catttttaaa aaaagagcta gatatatgag 189420 tagaacaaaa ccttctaaat gtcctcattg tgccggtaat attcaaaaaa caaatgaaga 189480 tttttcttca tttgtttcaa atattactaa tggtgaatat gaattaatta gcgaatatgt 189540 aaatacacat gaaaatgtaa aaatgaaaca taataaatgt ggaaatgtat atttgattag 189600 acctacaaac tttatatcac ataatcatag atgtcctaaa tgttcatcct ctagaatgtt 189660 ttcaaataaa gaaaaagaag ttttagattt tataaaatct ttttataaag gtgaaatcgt 189720 agagaatgaa agaaaattat taaaaaataa taaagaaata gacatttatt taccagaatt 189780 aaaaattgct atagaattta atggtcttta ttggcattct gaagctagac ttaataatgc 189840 aaaaaaatat cattatgaaa aaatgaaaga gtgtgaagaa aaaaatataa gattaataac 189900 attatttgaa aatgaatggg atttcaaaaa agatatagtc aaaagtaaaa taaaacatat 189960 tttgggttat aataactcta aaaagatata tgctagagat tgttacatta aaactttaga 190020 taatgaaact aaaaattctt ttttagaaaa taatcacata caaggaaaag atataagtaa 190080 aataaggtta ggtctgtttg gaaaaaatga tgaaaagtta tattcagtta tgacttttgg 190140 aaaaatgaga agatctcttg gtaataaagt ttcaagagat ggagaatatg aattgattag 190200 atttgcatcc gatatagatt atttagtaat tggtggattt tcaaaaattc taaaatattt 190260 cttaaataac tatgaagtat ctaaaataaa aacttatgca gatcttagat ggtcaaataa 190320 aaataataat gtatatgaat catactttca tctatcacac ttatcaaaac ctagttattt 190380 ttatacacat tcaaatagta agatagaaaa aaataaatat gtaaataggt attcaatgcg 190440 taaacatttg ctaaaagata aattcccaaa cagctacaaa gatgatttaa ctgaaagaga 190500 aatattagct aaagaaaact atttcagagt atgggattgt ggaaatttag tatttgaata 190560 ttgtaaagaa taatttaaaa aactgaggta acggacaatt atagttcgtt acctctatta 190620 tattgcaaaa atgtatctaa tgatatttta aatatatatt ataattatga agttgataat 190680 tattaatcaa ctaatttaaa taaaaggatg atttaatatg aatgaaatta aaataatgga 190740 tactgaacta ctacaggaag ctgtagaagg aaaagagaat aacggcggag gttacgaaca 190800 tactcgtacc gttttcgaat tccaaggaaa acaaggagtt ttcgaagaca cttcttgtgg 190860 tgatttcggt agcagattct tcatggaatg ggatggaaaa atggctatgt ggggaagtat 190920 gattgatgaa gaactcgaat acagtgaatt cgatgaacaa gaacaatcag aacttctaaa 190980 gcattttaga gttcctgttt ttgaagaaac aatctaggac attaatgtcc tagatttctt 191040 ttattttttt ttttctaaaa atattctatt ttatgattaa atatatatta taaaaataga 191100 tgcaattaaa tatattgaaa gatgttgttt tatatgtaaa gttttagaag aatctaataa 191160 gggagctgaa atagataatg atatattaca aaaataaagt aaatggtgaa atatacgaag 191220 ttaatgatat tcatagaaaa gatgatgctt tttattatgt gtttggtaat gaatttaaaa 191280 aagaaagaat aggattatat gaatcagtgg gtaaaaaaat tgatttatta gataaagata 191340 aaggacataa agaattaaac ttccaattaa attatgactc atctagatta tttttagtta 191400 cacatatgaa atatgataat aataatcctt ttgcacctaa agcagtagat ttaaagaatc 191460 aaaattttgt cgcatccgat tcttcagaag atctttacta tatattatat aaaagaatgt 191520 gtaatgcaat agatatacct ttattaaatt ataatgtatt attaaaagaa tttaattttg 191580 ataatgaaga tatatttaaa ataatatcag aagattgtaa agaagtaaga gattttaaag 191640 ttagaaatct ttttaaataa aaggagaaat tttaaatgga aaatattaaa ttgtataaaa 191700 atctagaaaa tggtgataaa tttactttat ctaaagatga aattaataat ggtagatttc 191760 tttataaagt catgaaacaa ataaaaagta atttttatcc atattataat tatgaagacc 191820 aacccattac aaccaatgga aactcttatt taattaataa acaactgaat ttccattttt 191880 atacacattc tgatattatt ataaatttta aaaatttaat tggaatagat gaagatataa 191940 taattaagag taatgaaaat aaagaaagaa atatttcatc ttcaattgtt tgtttctctg 192000 attctaatac aaataatgat agaatttatg aaaatatatt tcaaattgtt ttgaatacaa 192060 aaaaggctaa gaaaataaat cgtatgctag ataaatataa aagcgataaa tatgaaatat 192120 cttcttatac aatggataaa aatgaagtac attttaaagt tagtttcaaa caagattatt 192180 tgtctgataa gaataatgac gtttatgatt ctctagatga attgatatat tatatattaa 192240 agggccttaa aattaagatt gacaattcgt atatgtattt tatggattat ctaagatgga 192300 atttggaatt tattgctgaa gaaattactg atgaggacga aattaaaaaa tacttaatta 192360 aagaaaaatt taaataagga agtgtaaatg gatatgatat attacaaaaa taaagtaaat 192420 ggtgaaatat atgaagttaa taatattcat agaaaagatg atgcatttta ttatgtattc 192480 aataatgaat ttaaaaaaga gaattcgtct ttttataaat cttatggtaa aaagattgat 192540 ttatatgatg aagacgtagg aagtataaaa ttggagtttt tcttaattta tgattttatt 192600 aatcttcatt taactacaca cttttcttgg gattttaata atattccttt tatacctaaa 192660 aatatagaat taacaaatca aaatcttgtc atatcagact cttcaattga tctttattat 192720 ttattctata aaagaatatg tgatgtgata gatataaata tggcacatta taatattcca 192780 ttaggaaaat ttaattttga taatggagat atatttgaaa taatttcaga agattgtaaa 192840 gaagtaaaag atcttaaagt tagaaatcat tttagataag gagattgata aatatgagaa 192900 aagaaattag aaaaaatgaa agtaaacaat tgactttaca agaaaaatgg gaaattgatg 192960 cagaattata cagagagaaa aataaagaca agaaaaaaat aaaaggacca attataggaa 193020 agaaagtttc taaagaagaa atggaaagaa tcttaaaagg agaagaataa aatgtttaat 193080 cacaatatct tactatataa acctattagc attgattata atgattttat tgagttaaac 193140 aaagaaaaat ataaaaatga tagagaatat attaaaatga taaatgtatt taacttaatg 193200 gaactgttaa aaatagactc ttttaaagat aaaactttct ttgaaactga atgtaaatta 193260 aaattaagag gttatgatga atataaaaat ataaaagtgg tttacaatca atcattagac 193320 agtgatccaa tattctctaa tttaaaaaac tttaatgcag aattagatat tataagtaaa 193380 gaaagagata atacttatat gactgaagaa ttattatatg aatacaatat gatgaaaatg 193440 agcacatgta taaatgataa agctaacact attacaatta aaataaaaaa tttcattaat 193500 tcaaataaag aaaattttaa taacgatttt gaattcctta ttaaagaatt tgaaaataat 193560 ttattaaaga atttaacaga cctccataaa tatgaagact tacaacttct aattaataat 193620 gaatatcaca gtttaaaaga tattagtgta tataatgaaa aaatatttag acctgctact 193680 gataaagaat ttaagaatta tttagttaaa gaaggattta gatgaagtat gtattaaata 193740 tatattataa aaatgagata atgaattaat atgattcatt atctctataa taatttaatt 193800 aggagagtgg aaaagatatg attttaaaag agaatagatt ttattataat aaagatatta 193860 atgagctttt tataattggt aaagataaaa gtgatattaa cgataagata aataaattct 193920 attataaaaa attattagaa aaaaatttag attactatca tttaaataat gacctttatt 193980 ataatagaaa tctacgtttt gatttaattg ataatgaaaa tatttatttt agtaatatgt 194040 ataatggaat tagaaagaaa cttccagtgg aagccttaga atttgcatat ataagaatta 194100 gagataatca agtagttgta caattagaaa cttttattac tagaggtgac gatccaaact 194160 ttttagaagt tgaaaagaat gcaacgagtg ctagcataac aatggtaaaa gatttttatg 194220 aaaaagatct tatgagttat aatgtttatg aaaatgattt agataaacta tctaatttgt 194280 tggacacaat gcttaaagaa gaaaataatg gaagtattaa aatttttata aatgacattg 194340 atatatttga acctcatgca tattttaaag aattagaaga tgaaagagaa attaaaaata 194400 ttttggttaa gaaaaatttt atataaagga gataaatata atgaatgtaa atgaatatat 194460 aactaatcat gatttttaca gagttggtat taaaggtcaa gtatttgtat ttaataaaga 194520 tatatcaaaa gatgaattaa attctaaaat atttactaaa ttattttcat gcgaaaatat 194580 aggaattata ctgtccgaat gtggacatta tataatagat ggaaataata tattcttaag 194640 aaataatgat aaaatattat tagtagaaaa tatgactatt gatataagtt tatttaaaga 194700 tgatctaatt gaattaaatt ttatattaaa tattgaatct gatctttatt caaaaattgg 194760 tccttttgaa aaagataatc atgatccttt ttattattat aatactatta ttcaaataga 194820 aaataaagat aactttcaac atgaattaat ttctcatata acaaatcatt ttaataaaat 194880 gagtgatgtt gatttaatgc ttttaactac taaaaatgaa attagattta ataaagatta 194940 tagtattaat aaaaaatgta ttaattttaa atgtaatttt aatgaaattt ataaaatact 195000 taataaatta gaagatgaaa aagaaattaa gaaatatata gtaagagaaa attttaaata 195060 aggatagaat aaatatgaat ttagataata ttgtaatatt aaaaaagaaa aatgatggta 195120 aatttgacaa taacaaattt atagaattta atcataataa tattaataat gatgaaatat 195180 taagtctttc tttaattact ctatatacaa gcgtgtatgc attttatata aaaagcgatg 195240 tgaaacctga caattttgtt agttatttag ctaattttta tttagaaata gatgggtatt 195300 taaaaggacc tttaaatata acacatgatg aaaataatag aatgcttata atttataaag 195360 gaagactacc acaagatatt ttcaaagtta gagaatttaa cgtaaatact aaattatatg 195420 cgtatttaat taaagatgat gaatacaata cggtagaaga tgatctaatc gaatcagtaa 195480 tcaatggatc agaatatata atgaatagtg aaagaattaa accgaaaatt attattaatg 195540 gattatataa ggatattaca aatgtattaa attattttga aaaacttact gatgaaaaag 195600 aaattaaaaa atatctaatt aaaaaaaatt ttaagtagaa taaggaggat taaatttgga 195660 taagtcatta tatgtatcgg atatattcga tgagaaagtt ataggaagaa aggatcttaa 195720 taaagatgaa ctttttgatt tgtcatttaa tacaatttta aataattctg ctgacactag 195780 atttaataaa gaaggaatta ggttaatgtt atcgttttca aaaggattaa ttttaaaatt 195840 tgattatgca gacaaatatt tttatgtgaa agattttata tttttaatag aaaaagttga 195900 tggtaactat gaatttaatt ttacattaag tattccagaa tttgcagaca gtgaaattga 195960 aattgaatta ggaatttttg aatcggataa aggtcataga gaattttatt ttaatgattt 196020 ttcttattat aaagaaggaa aaactttatt agaaagagct aaagaatatt taacggttga 196080 tgtttttaat aattatggtg ttatttttag tattttttca ttaaaagata aaaatagaat 196140 tttaacagac gataatttta tcatagataa taatgatata gatgaaattt atagtctaaa 196200 aaatatagat aacgtattta gagaagtaac aaacgaaaaa gaaataaaag aatacttagt 196260 tcagaaagga tttagataaa atgaaaatag gcttagaatc ttatgaatac tattaccatg 196320 atgaagaaaa aatattagtt ccagtatcat tagatatgaa gaaagaaaat gcaaatgagt 196380 taatgacgtt tgaatattat aagaaagttt ttaaaagttt taatcataat atatttcata 196440 aaagaattca cgatgataat atactattta gtactcgatt aaataaagtg attaacaaaa 196500 gtactggtat atcaatacct gcttatgagt tatatataca ttttgaaata gataactcat 196560 taaatattat ttccttagaa ttaagttttt caatggatac aaatcacttt gatttattta 196620 gaacattcta taaagataaa atagaagtta taaatttttc aaagacagat tctttaaaat 196680 ataatcaaaa tgtagataat ttagaagata aaatggcatg tctattagct aaattattct 196740 ttgatatgca caatgatgaa aatgaagata ttgaaatata tgtagacgat ttttaccatg 196800 aatcattaga catagctaag ccatataaat attttagatt gatgggagaa aaagaaataa 196860 aaaatctagc aattaaaaaa acttttaaat aatttaatta actttctttt atattaataa 196920 atacaatgaa agagagttga atataataaa tgtctgaaac taatgaaatt gatttaatat 196980 cacaaatcaa tgatatgatg gatgaatata agatgttagt aaaatttaaa gataaaatgg 197040 aaaataaaga aattcaatta gaaaatcgta tacaggattt aactaagaat ttgaaatatc 197100 ctaaacatac attcgtatct aatatggaag ctaacattat tagtgtagaa aaagaaatta 197160 aagacactat tatgcaaatg aaaaatgtta aaaaagatat tattgactta actatgaaag 197220 ctcagaaaat ggctgaagat gatgaatctg aagataatta taaaactctt gctaaaaatg 197280 tacttaatga gcttaataat atgtctaata aagatatttt aaacagtatg atggaacctg 197340 aagaagtaaa tgatgaagat actgatttta gtgaagaatt agatgcaaaa ttatcgcaat 197400 tagatgaaga agagaaatct atcaataaag aagtagatca aaaagaagag ttgagtcaag 197460 aaattaatga attagatcaa caagatttat cttctatatt gaaagtctat aaaggtacat 197520 tacaattctt tgttgtagga gattctcctg aagaatatga attagtagtt gctgatatgg 197580 atatgaatat tattgaagaa gatgagatgg aagatgaata tccagaatta tttactatga 197640 ctagggatct tatctttgaa gatattgaag gtaatgatga aatagttaaa gatgaatttg 197700 gaaatattta tcaaaaagca gaattttaaa ttattttaac ccataatata ttaatacaat 197760 atattatggg tatttattat atgtggaggt tatgtattat gggatttgag ttaacaatat 197820 atggaataaa taaaagtaag caaagagatt tacaatggta tattaatcat catagatata 197880 ctaaagagaa gaaccattta tttgaattag aattatataa accacatgaa ctttttgatg 197940 tattaaaata taaagtaatt gattataaaa atgaagatgg ttttgatatt caagtaatag 198000 atgaaaatac tttaaaagag ttaatggaaa atgaattaag agaaaataat tttgaatatg 198060 gattaactca atactataga cttatgactg aaatatccag aaataaatat tttataaata 198120 atgataaatt tgatttttat ctaatcttag atgcatcatt ttaataatag gagatggaat 198180 agatatgtta aaaagattat atagtttatt aactaagaaa aaatttgaaa gaaaattata 198240 tgaatttaaa tttaattatc aagatcatga gcatttaaat caagttcata gagattcaaa 198300 taatatataa tatgaaagga tgattattaa tgttatcaga atatagatta aattcaaata 198360 aagaaaatat taaacaacta ttaagagatt atggttttaa aaaagattct tatactaaag 198420 ctttaatata tagaaaacgt gtaactgatc cgaatgatat tttattcata gtggctgaag 198480 tggttattga aactaattca gatctagtta aattaaatta ctatgatagt aaacataata 198540 gatttaatcc ttctaatgag tcgccagaag ttcaaaaagg tttaagtata ttagaagata 198600 tgaaagaaaa agaattatta attgaaccag aattaactca aaatgtagaa gaaaaagaag 198660 ttcttgatag acttaaagaa caacgtgaag aaatggaaaa tggtcaagta tcacccaatt 198720 ctgaaaatta gaataaatat atattataaa aatgttatcc caatactatt aaattagtat 198780 tgggattatt ataatagaag gagttaaata aatggagaaa attaataaat actacattag 198840 taaatcaaaa gatgaattta tggaattaac tttcaatgaa aatgaaacac tctattttga 198900 ctttaagtgg aaagttttaa gtgagctatt cactacaatg caaataaatt ataataagag 198960 atttcttata tctcatgaag aacatgatga cgatggttta gttgggctta gaataaattt 199020 caatgctttt cccacagtta aatacaaata taagggtaag aaaaataaaa tggaacttct 199080 tatatacgct ataatacgct ttagtctaaa tgaggaagac gataattata ttaagtttaa 199140 agctgttcct ttatataata atagtgaaat agggaaaaga ttatttagta aaagatctgg 199200 tatatttgat gataatggtg aactagattt accgcatgac tttaatgaag aagttatgat 199260 tcgcttttta aaatatttta aaagtcatat acaaaaaggg aaaagacctt tagaactcaa 199320 ggacgattta cacaagatgt ttactgctac aaataaatta atttttgaat tactagatca 199380 gatacaagat cattcagata ttgaatttct tattgcaccc gattgggatt ttagtggtaa 199440 agaaatggaa aaagaaaaag gttttagttt tgaaaaagaa tatgataagt atatcagttt 199500 aaatgatttt gatgttgatg catattttag agaaataact gatgagaaag aaattaaaaa 199560 atttaaagtt aagaaaggat tttcctaata tgaaaaataa tacaaaatat tttatagata 199620 aagaaagaga tgaattaatt gaaattgata agaattatct taaccgatat gaatatattg 199680 catatgtatt aactactatg gatattaata atcttttaag cagtaaagga tatgctaaag 199740 ctttcataga taatatttct aaagaagaag gttgtatgaa ttttcatgat atagattctg 199800 atagcgatat ttattttatg gacaaacata ataaaaatga tactcttaaa agatttaata 199860 ctaattttca tattaatttt aatgctggta gaatggataa aattgaaagt ggagaattta 199920 aattagattt tcattttgat aattcattat ataaagaata tttcaatata atcactaatg 199980 gtttagtaaa tgaaaataat ttagttaatg aaggaataaa tgaaaaaatg agagctctta 200040 taaatattga atcatttgaa aaaaatttat atgagatcaa atatagtaat gaatcattta 200100 tggatttaaa tttttcaata tcgggatatg agaaaagtcc tattattaaa tttacagaaa 200160 aatttaaaga tttattcttt ataatattat atcagaataa tcttagtgta ttaatgtctc 200220 tttatgagat taaatatatg tataaagacg atatagaatt ttatattagt ttctccagta 200280 agggtggcgg tttaattaat ttattacacc taatagaaat tgatgaaaat aatttattta 200340 aagaattaac agatgaaaaa gatattaaaa attttaaagt taagaaagga ttttcataat 200400 ggaatataat aattactata gatataaatt agatggagaa atacttcact ttgatatgga 200460 tagaactgac ttaagaaggg atatattggc tgaaatattt actaaaatgt atatgaaata 200520 tattaataaa gatgaagaaa tgattaaaac gtcagaaaat tttatttatc gatctgatct 200580 ttctttagaa tattctcatt ttaaagataa agtatgtgaa atcagacaaa tttctaaaat 200640 aatgggtaaa aaccatgtaa aagatttatt aatttacgat acagatatta gtttaggatt 200700 taattctatt ttagatggag ctatatttaa aaaagatttt ccagaaggat cttttcatga 200760 caaaatagaa agtaacatga atagaagata tttaatttta agtgataata taagtcatac 200820 tagtgaaagt tttgctgatt tatatgacaa agattatatt ttaaattttg aagaagtaga 200880 atttttagtc aaagaattta atagaacgtt tttaaattat cttatggatt taatgagtta 200940 tggaaatcta gaattaaatg ttagaaaatc ggagttagca tattttatga cagggatata 201000 tacaaaaatg aaaaaacatg aagacagatt attccctata ttcgattata aatttttact 201060 taatgaatct ggattatttg aagagattac ggatgaaaaa gttattaaag aatacttagt 201120 gaaaaataat tttaaataaa ggagatcaat ataatgagtg caatgaaaag taataaaaaa 201180 tacttcctat gtaaaataaa tgatgaatta tttgaagttg ataaaaacaa tagaggttca 201240 tttttatatg actatttgcc tttaataata gctgaaaaaa taattaatca gactgaaaaa 201300 gattcatatg aaactagtgc aatggatgtt tattataaaa aagaagataa tataattaaa 201360 ggtaatttaa aatttttatc aagatgttta cttcctgtcc tgtataattt caataataaa 201420 aattcattta aaaccgttat gactctcgca gattttaaat ttaaaaggga tgctaacaaa 201480 tctactttta gtatagataa aaatagtgtt aatgataaaa tactatttca aatgagacct 201540 ttaggaaatg aaattgatga tattttattt aatagtatta taagtgacct tttaaatgaa 201600 gatgacgaaa tagaaatgaa acaaatgtta ttagttggta attttgaaaa attattaaac 201660 gaaattgata atcaaaatat aaaacatcat gatgatttta aaattttaat caaagatata 201720 tttaatattt atattaattt attaaactct ttaagtcatc atcttaatat tgaatttttc 201780 ttttctgaat cttctttttt agacatgtta aatgtttatg attatgatat cattaataat 201840 aaagatagtt ataaaataaa tatttttgaa gatgatttag atggaatatt tgaagaaatt 201900 accgatgaaa aatttgttag agaatattta gtgaaaaata atttcaaata aaattaaaaa 201960 tttatagtaa cggaaatata tttatcaata ggagttgaaa ctggataatg aagattaaaa 202020 gattaaagtt aaagaatttt atcggtattt atgctggtat gggattaaaa gaagttgaaa 202080 ttgattttag taaaagtaaa aataatatga ttatgcttct tggagataac gcttcaggta 202140 agacgacagt tatgtctaat cttaatccat atagagaaac taatgatcaa cgtaaaacta 202200 tagtattaga agatgaaaaa ggtataaaag agattgatta tattaagggt aatgatgttt 202260 atgaaattaa acatcattat ggtaaaaaca gttctcaaaa taaatcattc attaagaaaa 202320 atggtgaaga acttaatgaa aatggtggta ttaaattatt caatgaaata gtagataaag 202380 aattaggtgt atctaaagaa tactttactg taggtcgttt aggcgataac gtatcaaact 202440 tcattgacta tactacaggt gatcgtaaat catatatcaa taaatttgta cctaatattg 202500 atagatactt agaagcttat aaagtagcta atgagaaatt aaaaattatt actaaagatt 202560 taaaatcact tagatttgat ttagacaaat ataaagaatt tgatgaaatc aaaaaagaaa 202620 aagagaattt agaaacttta attgatcaat tacaaaatga acttgatgaa gctaataaag 202680 ataaaacaac tcatgaaact aaaatgaatt ctatcatgga agataagtac aaagagattc 202740 atccaactga atataaaaat caattaatta atgaaattaa tgaacttaat caagaattag 202800 aaaaagaaag aaagttaaaa gaagataatg agaatttaaa taaatatact attgaatccg 202860 ctaatgagaa aaaagataaa atagatacta tattaaataa tactaataat gagttgactt 202920 ctgttgaaaa agataaagag aataatcaag ataaattaga tgatttaatc agtagaaaat 202980 ctaaaataga atctcgtatg aatgctatca aatttaatga agattatgat gcttctgatg 203040 aaattgattc aattcttgaa ggatataaag aagatttaga aggtattaaa gatgatgtag 203100 atatttctag agggtctttt gtaagtgaat tcggtttaca aattaaagat aatattaaag 203160 aggattcatt aagattatat gtaaatgatt taatttctaa ggtagataat tttaaagaat 203220 ttattaatga taatgaattt aaatatggtt ctattcgtgg agattttgaa agtgaaatta 203280 aagataataa tgaaaaaatt tctatgaacc agaatgaatt taatgaaatt aatactaagc 203340 ttaatcaaat taaaggcaaa tcagacttat taaaaatatt agatcaaaaa gatcatgatc 203400 actataatga atgtgtattt gttcctttag tagctgactt taaagacaat gaatttgatt 203460 caatctctga attagaaaat aaaggtaatc aactttataa agataatcaa gaattagaaa 203520 aagataataa attattatct aatcatattg acttattacg taaatttaat gacatactta 203580 ctagtagaaa tagtttaatt gaatatattg gttttgaaat gattgatatt gatagtattg 203640 aagaaatatt tacaaatggt aatacattct ctagtgaact aaatagactt aattcattaa 203700 ttgaaaagac aaatgaaatt cgtactaatg aaactaatag agataaattg actattgaat 203760 tagagagaaa agaaaatgct cttaaagaag attattctaa taagaaaata ttagatcaat 203820 ataaagaaga taaagaagat ttagttaaac aaattgaaga aattaaaaat aaaaataatg 203880 aaatttctga gaatcttaat tatcttaatg gtcgtaaaga aaaagcaatt actaacttaa 203940 atattattaa tgaatttatt aatctaacag agagatctga agaaattaaa ttaaaaatga 204000 aagataaaaa tgatatagtt gatgacattg ataaggatct ttcaaaatta agtaatttat 204060 atgaacttaa tcaaaaagca gacaataaaa ttcaatctat taaagataat ttaactatga 204120 agaaaaatga tttagaatct actaaagaaa aatactttgc agttaattct attattacta 204180 agattgatga aattgaatca gtgttatgga aatataatat ggtggtagat tcattaaatc 204240 ctaagaaaga ctctatacca ttaatattca ttactaatta tcttaaagat attgcagtaa 204300 gtactaatga attactttca gttgcttata ataattcatt taaaattgac tttgacttaa 204360 cagataaaga tttctttatt aatgtgtata aaggtaatgg aactgagctg aaagatatta 204420 aagaagcttc tcaaggagaa acagctttaa ctaatattag tttatcttta tcattattaa 204480 acaaagtatc tcaagattat aatattctat atttagatga aatggactca acattagatt 204540 ctaataatag aagaagattt gttgatgtaa ttgacagaca aattgaatta atgggtctag 204600 aacaagtatt cttgattagt cataatgatg aattctatag tgctaatatt gacttaattt 204660 tacttaaagg atacgaaagt aaaattgaca ttaataatga agaaatgatg caaggtaaaa 204720 atgtattatt taaagtaaac taaaatttgt tattaaaaat ttgagaggag taactctatt 204780 tgaatattaa tgttaataaa cctttagatg ctaaattcga aaaagaaatg catgataata 204840 ttataaatgc attcattgat agcacgttag gaccaatcct ttatgaaaaa ttagaagagc 204900 tatgtaaaat tcatgataaa aatataaaac tttattatga ctatgatatg ttagattcta 204960 aaaaattaaa acatagtttg attaaatttt atgaagaaaa taatttagat gaagacgaat 205020 tcattataaa gattaaaaaa gaagttgtta aaaatgcgtt taaatagaaa aggatgattt 205080 tatatgaata aaaagaaatt atggataatg acaggtataa cttttttaac atctttcacg 205140 ataaatttta ttattctata ttataaagat aaatatagac aggatgatat tgatacatct 205200 gaagatccat ttatgaaagg tccattattt atatagttta aatattgcca aacattcttt 205260 aaatagagtg tttggcattt atattttaat tttttatgaa atctaagtaa cgattaaatt 205320 atcaaagtag caattgaatt gaggagtgtt caaagataat gggtagattt attaaatcaa 205380 catatttaaa taaaaaagag acacattcag gaaaagaaaa agtggtaatg gtagttaaag 205440 aagaagacgg taataaaaaa cacatggaaa taactgatcc gatgatgcat tactatgtaa 205500 ctaaagatga acattggtta ccgcctaata aaattgtagg ttctattgaa aaagataaag 205560 taagaactgt tacttgtaag cataaagata ttatcaaatc agtagttaaa gaagctggta 205620 atgctcaaga taaagcagaa tatgatagaa ttatgaaatc aggtaattgg caagaatata 205680 gaaaattaaa agattttcat ttattaaata atgctcatgg atctgatatt aatatagaag 205740 attataatat taatgagtat attaaaaaga atttagatag taaagtcggc atagatatat 205800 gtctattcga tattgaggtt gatggttctc aagtaactgg gttaaaggta gctcaggata 205860 aagcttttta attgctggga agtccttaga gcttaatgaa ctacaacgta atgagtaatc 205920 ataagcgtga atgtttaaaa atcattaaga ttggaaaatc agcagctaat aataaaattt 205980 aattgaaaat aaaatttaag gtatgataaa gttggaaata tggaaagata tagaaaatta 206040 tgaaggttat tatcaagtat cagataaagg aaatgtaaaa tctttagaaa gaaaagttat 206100 tgaaaaaaaa tactggcaaa gtcaatattt ataaatctag aaaccttaaa aaatcatata 206160 ataaaaaagg ctatgagcaa gttagtttga ataaagataa taaaaagaaa actatctttg 206220 ttcacagatt agttgcgtct gcttttttag aaaatcctaa taatttacca caggttaatc 206280 ataaagacgg tataaaagat aataataatt tggataattt agaatgggta actaatgcag 206340 aaaatatgga acatgctcat agtacaggtc ttatgaaaca tatcaaaatg ccttctggaa 206400 aagatcatca catgtttggg aaaacagctt ataataaagg taaaaaaatg agtgaaaagc 206460 aaagacaggg tatgatgaaa cctatcttgc aaattgatat gaaaactgga gaagtagtta 206520 atgaattttc aggagctaaa gaagcagcag atattttagg tttttctaga agatcaataa 206580 cagatacatc aaatggaaaa caaaaaagtc ataaaggttt tttgtggaag aaaaaataat 206640 tcaattaaat tttattaaag ttcaacgact atcaaaagca tgtcaaatgt gagtagagta 206700 cagccaagcg gttagttttt aagtgatatt agcttaatgt aatactatta aatggaaaag 206760 gaagcatctt aaattttaag gtaagatata gtctcaacgt ttagggaaac cctaaagaag 206820 ttcataagag aactggtata tattagcgat atatattgaa gattttgtcc ccgaccctga 206880 aaaagctgag gcagaggtaa atattataac tgtagtggac tggagtaaga agaaagtatt 206940 aacatttgct cttaaatatg atactgatac ttatagagaa actatgaaag atcaagataa 207000 attaattaaa gacttaaatg aaatttataa taatgaaaat agtgaaattg gtaaagattt 207060 aggtttagaa tttgaaatat atgagttaga tacagaaatg caagttatta aatctttctt 207120 gtattatatt aatgaaatta gtaagcccga tatatgtacc gcatggaatc tagattatga 207180 ctttcctgca ttatttgaac gtattagagc taacggagaa gatcctgcag attatttctg 207240 ttctaaagaa tttgaagata aaaaagcata ttataaatta gataaaaatg ctactgatat 207300 ggctaataga tcttctacat ttgagactaa ttcatatact aactggattg accaattagc 207360 tttatatgca aatattaata aacctaatgg tgctttggaa tcagttaagt tgaatgatat 207420 tggagagaaa gaagcaggag ttactaaaga tgtttatgaa ggttctattt ctgatttaca 207480 ttttagagac tattatacat tcattcttta taatattaaa gatactgtat tagctgcatt 207540 aattgaacat aacactaata tgtttgattt attattctct attgtagaca tgactagaac 207600 aagacctagt aaagcactta agaaaactat ttgtttaaga aatcgtagtt cagtattctt 207660 tgaaaatcaa ggatatgtat taagtaataa tcactcaaaa ttattatcag atccgaatgc 207720 agataaaatt cgtggtggat ttgtagctga tatgatgtta attgaacgta atggtgatgt 207780 attagttaaa ggtaaagata ttagatctaa tagattattt agtaatgttt gtgactttga 207840 cttaagttct ctatatccat ctattattag agcttataat ataacgcctg aaggacatgt 207900 aggtaaaatg aatattcttg ataaaaatag aataacagta cctaaatatg aggaagataa 207960 agataactat gatttcaata ctgaattcgt aagtaagttt aatagtcaag atagtgttgc 208020 ttttgctcaa gaatttcatg gtttaccttc tcttattaaa gcatctgatg acattattaa 208080 agaattagag gaggaaattg gttaatgtct attattattg aagaatcaaa aatagtaaat 208140 aaattagtaa tgacttttga agaaatatct aaattattca ataatattgt tgatggaagt 208200 aagtatatta gtttaaataa aaatattata acaaatcatt ctaagtcaga tgacaatcct 208260 aattcagttg aagtggaaat tatagaagat aatccaattt acgattatct tctacctatt 208320 gaaaattgtg tttttagtgt agaagacttt attgaagtaa gaaagaataa gggagataaa 208380 attgttaaag ttgaattttt caatgaaatc gataatagtg gtattaaaat aactagagaa 208440 tctgatttag aaactattat taacggtgat gaatttgatg aagacttatt agatgaagaa 208500 ttaaattatt cactagatgc tattgattat tttagttctt ttgaaccaag tctaaatttc 208560 aaattagatg atgatagttt attggaaatc aaggaaagaa aaccttctga gttctttaag 208620 tttatattta ctgaagatga tgttattgtt aaagatcctt attatattta taatgaagaa 208680 gactacctta ttgattttag aacttctaaa aagtatttat taggattaaa atataaaaag 208740 actaaaggag aaacagtttg tccattagtt aaaatagatg tatacgcccc agaaacaact 208800 gtatatagtg aattgattat gataaaattt tcaatttacc aagacaaatt tgttgcaaaa 208860 ttgaagaatt tagtttataa tatataatgt gaaaaaatac ttataaatta agagaaaatt 208920 ctaaaaagta ttgaaaagga gtgttttgaa tttggctgat gagaataaaa ctcagagaag 208980 tataaataat ctcaacagag atatggtcag aggattagga gatgaagaaa atcctaagaa 209040 cttatctgat aatataaatg attttgatga taggctaaaa aagataagac gtaaaagtaa 209100 tcatggtaat agtaatggtg atattctatc tttagcatct aaagtaaatg gtaaagatag 209160 aaatgctaga agaactaata atacaagtga tgataaaaaa gatttcatta aagactttat 209220 agaagagaat attgaaaatc aagatttttc atctgaaatt gctagagtat ctagatatga 209280 tgactataga attatagata agtttatacc tgaaatatca acaagtattg atgtattcgc 209340 tacttctatt atcgcacctg acgatacttc taaattatca ttgatgtatc gttatggtga 209400 tacaaataat aaagatgaat cagaaaataa agaagtttta aatgaattag atagaattgt 209460 aaagaaatat aatttagaca atttaacata cacttctatt cgtgatggtt tattattagg 209520 tgatgtattc tacattatta aagatactaa atctgatttt gaagaaatac ttaatgaaaa 209580 tgatgatgta ttaggaagag aaacacgaga agatcaaaaa gtgattaatg aatcatttat 209640 agatcagaat cttaaagaat ctgatttaga cattgtaatt aatgaattta atagtcaatt 209700 tgaaaaacct attaaagatg aaaatcaatt aaatgaacaa agagctaatt ttaaaaatga 209760 aatattaaag agcattaatg agaatgtagc tttctttgaa aattcttctg aattactatc 209820 tgatataggt aaatacaaag gctctaatga cttacaatca tttttaaata aagcagataa 209880 caaaaataaa tctagtaaat taaaatctgg ttcagtttat tttagatctg tagagcctga 209940 agacatgatt aaattagaaa ttgatggaat gtgtattggt tatctttata ttgagcctga 210000 ttctggaact gatttaagag gaggagctaa tcctttatta tctgccatga ataatttaat 210060 gggtgacggt tatcagaaac aaggtcagac agggtcattc gcaaacggta tgggagttac 210120 taacttagat cctgttactg gtaatgttgc aggaaataat atgtctagca attctaaaaa 210180 tcctaattca ggaatgaatg ctacatccgg ttcatattat gaaaatggaa atactgctat 210240 ggcgtatcaa ggactagttg atgttatagt taaaggtatt tctcaaaaaa ttaatatgga 210300 cttcattaat aaaaatgatt catttaaaga tattatatat agattaattc gtaagaatta 210360 tattattgaa aatggtatta aaatgacatt cttagaagct gatgaagtat ttcatcacaa 210420 attagacagt caaaaaactt atggagtttc taaacttaat aaatcattat tctttgctaa 210480 attatattta agtacattaa taactacaat gatggttaaa ttaaatcaat caagagatag 210540 acgtgtattt agagttaatg caggtttaga tgatgattat gaaggaactg tagaagaaat 210600 aattcgtaat gtaagacaaa atgaaatgtc tacaggttta tttggtgatg gaacttcagt 210660 tcaaacatta tttaatcaag taggtaactt agaaaacatg tatattcctc aaaataaaga 210720 gggtacttca cctttagaaa tagatacaat ttctggtatt caagttgata ttaatgatga 210780 attcttagaa tggcttaaga aatcagttat atcaggtaca ggagttcctt taaattatat 210840 tgatgctgag actgaaactg attacgctcg ttcattatca atgcagaata ataactttgt 210900 aagacgtgta gttaactatc aaaaatcatt cggtgaattc tacactcaag tattaagaaa 210960 gctttattat ttagaaaatg taaatattaa agataaaaaa tataatgaag aattaaataa 211020 taaattacaa gaaattgaag cttacttccc agcacctgta ttcttaaact taggaaatct 211080 taatgaagaa gttggagctg taacacaaat gatagatttc ttagttcctt tatacacttc 211140 agaagctact ggtgacgaag aagaagatga taatgaaaaa ttaaaacgtc tattccgtaa 211200 agaactagtt caacaagaat tcatgtctaa tttagattac gatagatatg aaaatatcat 211260 taacaatatt aaagatgaaa taaataaaga caaaaagaaa aatgacatga caaacaataa 211320 taatgctgat ggagacgatt tagcttctcc aaatgattct gaaaatgatt cagatgataa 211380 ttttgaggac gatttctaat attgacattt gaataacgga ctaaatacaa ttcgttattc 211440 aaatttatat tatataagtg tagtacataa tatttattta taaggagaat gaattagata 211500 tggcaaatga agaaattgtt ttagatttaa aattaggtaa gtacaatgat tatttacact 211560 cagataatta ttttgaaatt ttagatgatt taaagaaaga tatcattggt aatcctcaaa 211620 aaagaatgga agactatttt gaagacaata tacccaaaag taattatttc actttattag 211680 tattaggtaa accttttaga gatatgaata aagaatttac tgaagagtat ttagttaatc 211740 caaccgatat tgatgattat tatgactatt ttgacaaagt tgttgttaat tttattcatg 211800 aaggtcatga tccaataaaa gttagtcaat caattgcatt tgttattgac gaattgacta 211860 tattttcaaa tgaatatatt ttacctttag atggtccatc tatttcatta tatgatatta 211920 tgagattagc taatgaagat aaagaaatag aaaaattaat taactttgat aaagaagaca 211980 ttgatcataa cttaacatat caacaaatca ttaatgaagt tcaaaaaccg aatatgcata 212040 aattgattga tcgtattaaa tctgataaag aaaacgatta taaaactttc ttacattcag 212100 gaacaggtat taataagata caattgaatg aggttttaag ttttgtagga tataaaccag 212160 acattcgtgg tgatgttgta actgatatta ttgatacttc atttatgcgt ggtttaaaag 212220 atacaacaca atttgctatt gatgcagaat cttcattaaa cgcattaatg aactctaaga 212280 ataaagtacg tgaatcaggt tacttaaacc gtaaaattac tttattaact tcagacttaa 212340 aactatcaga aactgaagat tgtgaaagta aacatttcgt ttacgttaat atggatagtc 212400 aagataaatt agatagattt aatgatagat tctattatga tgatacagat caagaattaa 212460 aattaattaa ttctaaagaa gacagtcatt taataggaca aattgttcca ttacgttcac 212520 ctattacatg tgctgaatct aaaggaaaaa tttgtcaaac ttgttatggt aaacgtttat 212580 ataacattaa tagaaactta tctgtaggta tattagctac attaagatta acagaaccta 212640 tgactcaaaa attactatca acaaaacact tacaggcagt acaattatct gaattctctt 212700 ggccagatat ctttaaagaa cactttgaat tctctggaga taatattgtt ccacgtaatg 212760 aaaagactaa agttattatt gatgaaatga ttattaatga agattatgaa tatggaagat 212820 ataaagctaa tagttttaaa tttaaagtag gtactaaaac tcatactgtt aaatcacctg 212880 taactcttaa aataccagac caaaatattg agactatgga taaattttat gatgaagaag 212940 aaaatgcatt tatattcagt atgaaagact taaaagagaa tttcttattt aatattaaaa 213000 ttaaaaatga aggcgttgct gacccacttc ttaaaatacg ttctatatta gaaagtacta 213060 aatatattag aaatgactat gaagaaaata attatcaagc tatgtttaat gatgtaacag 213120 atttattact taaatcaggt acagacgtta tgagtgttca tttagaaact attattagaa 213180 atatggtatt cttaaatgaa gattataaag aaagaactaa atatagagac cctgaatttg 213240 aacctgatat tgaattgaaa aatgtaggta gtgctatttt aagttcacct tcaccagttc 213300 aatcattaat ctttgaaaag attaaagctc agttaagcac tgatgaaact aataacttct 213360 tcagtaaaga tggagattca atgttcgatc cattatttga ttttgatatt taaaacaata 213420 taattcaacc aaacttctat taacttagga gtttggttat atataataac tctaggagga 213480 atttaatatg aaagcagaag atttattaag agacaattta tatgagcaat acgattataa 213540 taaggatgat aagttagaaa aggctataat gaagaattgt tatatcattt ttgacaatgt 213600 aaatgaagat ggagagagaa atatctatag aatatcagat ttggaagtaa atgaaaatca 213660 aattttatca tttattttag ttaaagatga tatacctgtt tcaactcata gtttttcaat 213720 tgaaaatgtt tatgaattta atgaacttga caagcttata ttagaaagta ttaattctta 213780 aaaaattaat tttttataat aactgataga tataaaattt taaagcaaaa aggagaattt 213840 aatttaacat ggaaattttc aaattaaaag aattagaagg taaacaagaa caaacaatcg 213900 aattaactgg tgatgataaa aaccttaaag aaattagaga agcatttttt aacagtcaat 213960 caggtactta tatggtaaat aaaactatca atgataatat tgaagaattc ttcaaacatg 214020 ctgaagatgg tgtaactgta gatgatgttt ataaacttaa tgtaattgtt gaagatgata 214080 aacaaattac tttagttaaa gctgaaaaag atgatcaatt taagaaaggt tgcttctata 214140 tggtatttga cttaatgggt tctgtacctg tatatactga tttagaaaat cctgaagcta 214200 catttgattt gtctggtatg tttaaagagg atggtttcga tttctttaaa actattgcag 214260 aagtattccc tactactatt gagcttaaac aataaagaaa gaagctgata ctatggtagt 214320 attaaacgaa acaagaaaaa taaaagtatc tgtatatcct actcgtatat tagttgaaaa 214380 ttacgagtta ggattttgtt ctgcagtaga aaattattta tcagtatggg ataaaatata 214440 tcataaacat acttataaag cttttaagta tgatgaagaa aataaaacta tatcttttcc 214500 agcaggtatt aatactaaat tattattaca gtcattaaaa aatcatggag aaattgatta 214560 tcaagatttc agagcagttg aaaatttatt ctttaaacct aaaccaaatt acgatgttga 214620 aatgaatttt aaacctagag atcttctaca aagaaaagct atagaattct taaattcatt 214680 tagtatatat gatccatcaa cacaaaaatt cctttcatta caaactggtg aaggtaaaac 214740 tttctgtgct ttaaagtcag ttattgacag agaattagta cctatgattt ttgttaataa 214800 caataaactt aaagagcaat gggaagaaaa aataaaagag tacactaatg ttgatgatga 214860 aaagatatat gtgattcaag ggagatcaag tattaataaa ctatttaaaa tgaaatctaa 214920 agaaagaaat aaaatagatt tctatatagt aatgtataaa acgttaaatt cttttattca 214980 agaagacgaa gaaagattac aagaattact attaaaaact aaagtaggta ttaagatatt 215040 tgatgaagca catttagatt ttcgaagttt aactaatatt gatatacaaa cagatttacc 215100 atcaatatac ctatcagcta cacctagaag atctgataaa tcagagaata tggtatttag 215160 caatatattc ttaaaaacac ctatatttag ttctgataat tacgacagac agatagctaa 215220 taatagaaaa ataccatcta aatatcatga tgtatttatt atcagatgga atagtaatcc 215280 taaagaagtt gaattagctg atttcatgaa agcttctaaa cgtaatggtc ttaatgtaaa 215340 tcattatagt aaatacttaa ttgaagaaga taaaagaaga aaagaatact ttgatattgt 215400 atttaatatt attaataatg tcattatgaa agaagaagtt aaaaagactg tagttatgtt 215460 taaattaaag aatatgatag atgattttta ttcatattta gaagataaac ttggacctga 215520 aggattagaa tttttaaatt gtattagata ctatgatggt attgataaag aagaaaaaga 215580 taaagtatta gaatctaact taattattac cactgattta tctttaggaa ctggaataga 215640 tatacctgat ttaaaagctg taattaatac agttccttta tcaagtgaaa gtaaagtaac 215700 tcaaattatg ggtagattaa gatatattga aaatgaaaaa ttgatgttct ttgatttaat 215760 tgatcatggg tttaagaaat tggtttctca aggaagtaat agattaagaa atgtatataa 215820 gaaaaaagct ttaaatataa ctgattttaa aattaaataa tgaaaggttg ttgaggtatt 215880 gtgtccatta tatctcgtgg agaggctatt gataattatc aatacctcaa tgaattattt 215940 ataagtttta gaaaagaaat taatgaattt ttatctagtg agatatttaa aattaatcat 216000 actgatttta aaaactctat tataggtagt gttaattcag aatttaaagt taaggaggaa 216060 aaagattcaa tatgcttatt gttagaagat aaatttattg aattcgacct ttatgaagga 216120 tttattatcc tttacaactt taaagagaat attagtttaa tgaaagaaaa aattgatatt 216180 caaaaatcta taatagaaaa taaattagat actagatata attctaataa taaacttaaa 216240 aataagaata aaaagtttaa caatgaaata actgaaaaga ataatgaact taatgaaaga 216300 attaaattag gtgttttaac taatgcatta ctaaatatgt taagaatgcc caattcattt 216360 aaattaaaag aagaaataga tgaacttaat aaaagtattg agaaaaataa tctaattata 216420 gagaataatg atagtaatat aaaattatta gaagaagata agaaagatat tagtaaatat 216480 gattttaggt ttgccaatga taaatatcta ttcaataaga ttagtgagtt tgtacagtac 216540 tttaaaaacg aatatggttt tgaattttat attaaaaatg atactatata aggagtaaat 216600 atatgaatag agaattaagc aaattaagtt tagaagagtt gagtgattta aaagaagaaa 216660 tcaatagatt tttcaataat gatttattta aatttccaag aaaaggactt gtagaacatt 216720 taactttacc tgtagaacat tataatcttt taataagaaa tataatagaa gatagtgaat 216780 tgaaatttac ttttgttggt gctgatatga ttatttttga tttaaatgat ttgaaggtga 216840 agatgtctaa taaatataaa cataaccttc aattagccaa aaaatctcta tactataatt 216900 atgacggttt ttcaggtaaa gaaagacttt cagatgtaat aaaaaacgaa aaagagttaa 216960 tagaagaaag gtttttattt gaaaataata taaaagctat taataatgaa atatcaaata 217020 tagagaataa atttggtatt aaatttgttt ttagtgaaaa ttttgaagga tacgaaatag 217080 aaataaatga aaaatctgat gaagcagaaa tttatatttc aaaaaataaa gaagaaactg 217140 aaaaagaaaa tataattgaa gatgataaga ttactaaaga aagtaatgaa catgaaatta 217200 cacatagtaa aaaagattct ttaattaaaa gaataattaa gagagtggtg aaattttaaa 217260 tgactgaaga aaaattacct gcattaaata ttattgcttc tgcagtaact actacaccta 217320 agactaatac agagtttatt aatatgacat ttatggtgga taatcctaaa tttaaagata 217380 tgtatttaga attttctgat attgatttat cagaagtatt taaaaacgaa atgcttaaag 217440 aagcttatga aaacggtcaa ttagcagagt atactaaaat tgatcagact ttagataatt 217500 acaatattag aatgattaaa gatgatacag ttatacaaat acaacgtatt agagattact 217560 ttgaagaatt atctgaatat gctgataaat taatattctg ggttgatgag attactttat 217620 ggtctcagtt aatagaatta gtttatggag gttcatcaga taacacatat caattacctt 217680 catatattga cttccaacct attgacataa aatcagtagt tagaatgtca gctataagag 217740 ataatgatta ttcatatgca gaagaattaa tgggaacaag tgaatcacta acagattcat 217800 ctttatcaat ttcatcattc ttattaacat tcattaaaaa tgctggaata ttaaaataaa 217860 tttttaaata tatattataa agatgtatta gtaatggaat attattaata taaataattt 217920 aaatggagag tgtcagatat tatgttaaca aattttaaag atcatttaca cagaggcgga 217980 aacctttcag tttcaattta tactttattt actagaaaga ataaaaatac tggtaatgct 218040 attaatggtg agtatattaa cacgtatcaa tcaagtcaat ataacggtgt tcctttctta 218100 agtgaaattg aaaataatgg taatcattat atttctttct cttataacaa atttcaacaa 218160 ggtcaagcac ctattcgtga agatgtatta attagttatc cacatttaca agaatttaat 218220 aatttcttaa aagcgactta tacaagtatt agtgagaatt ttaataatat tttctctaat 218280 aatcaagtta atccagatta ccaacaacat atttggcaat caccaaaatt agtgtctggt 218340 aaagaaattg ctattgctcc tgcagtaatt caaaataata gaactaataa ttttgaaatt 218400 ggttttaata ttatggtaaa tgatactaat aaatatgatt ttgtatcagc taatacattt 218460 atcagtttag ttaatttatt agttagaatt actaatgatc cattaacatt cagaaatcaa 218520 tgtgtacaag ctgaaatgca agctaaagaa attgaaaata atcagttatt aaaagggtta 218580 ttaagagctc aaggtttacc tacagatatg agtaatcatc atatggatga aaaatcagct 218640 caaggtaatg ctccacgtaa taataacttt aataataaca gtggtggagg tttcaataac 218700 aataatcaat tcggtaattt cggtggtaat aacggaaatt ttaaccaagc tccacaacaa 218760 aataaattta atcaacaaca atctaataac caatctcaag gaaattcttt tggaaatttt 218820 aatcaacctc aacaacaaca gaatcaacaa ccggtacaac aaaatgacaa tcctttcaat 218880 gtgagtccgc aacaatcagc accgcaacaa agtaatagta gtaatccatt tgatgttggt 218940 caaacggatc aaattagtga tgatgattta ccatttgaaa ctaaagaaac tccacaacaa 219000 gatgatagac aaattgataa atctaacatg tttaaagatg ctgaagttaa caaagaatca 219060 ggttctttag aagacttatc aaatacagta aataatgaaa gtgaaggtaa agctagttct 219120 ttactagacg acttcattaa aaaaggtaaa gaatcagaac aagaagatga cgatttagga 219180 atttaagaat taaataatat atgatctaat atggataaac atctgtatta gatcatatat 219240 accttttatt ttttataaaa aataaataaa gtgagtgaat attatatggc aaataaaaag 219300 gatctaagtg agttagaaag aattataagt agtatggaca ctattgatgt tagagaagtt 219360 tttaaagacg taagaagttc agataatgtt aatgaagaag atgatttaaa ctcatctaaa 219420 tataaaggtg acattaaagg tttagtaact aaagaagaat atgaaagtct tccatattta 219480 ggtaaacgtg ttattcagtt tatggaaaat attgcagctg ataaagaaaa tttagatttt 219540 gaatcttatt ttgaaagata tgcaaaagca tacggtaaag atgaaattga ttcatttaaa 219600 aacactatgt atagacttaa aagtagtaag gtttttacaa tacagtcatt aatgacaatt 219660 actgaagcta ttgattataa agttcatata ataactgaag aattcaaagg tatggatgaa 219720 ttaagattat atgaacctaa acgtaaagtt aaatcttcta gatttatggg taaattaaat 219780 tttgatttaa tgccagatgt tatatatgaa gactttatat tagagtttgt agagttttta 219840 gaagaattag gaaaagaagg atatactttt gagatgttat ttggagaact tgaaattaat 219900 tctgatgaga aaaatcctat aagtaaaatt aaatcatcta tggataaaat gattaagcaa 219960 ggtaaactaa cttggaagac tatggaaact ataacagagt ctttaggtat gaatattaaa 220020 gttgatttta taaaagacgt tattgatact gatgaagtta ataaaattga tgcatctaat 220080 caaatacaac tagaagatga taatataatt cataagaaat aaaatatatc ccctaacctt 220140 aaattaataa ggttagggga atttatatca ttttttttta ttctgttgta gtttcttctg 220200 gagtttcttc tacttgtgaa gtagaaatag taacactaac atctttactt acactatcag 220260 aagtgacttt aactttagca gttcctacag ctttagcagt tacaagacca ctgttgttaa 220320 ctgaaacaaa ttcagatcct tctgtaatag aatagtttac agggtttcct tcaggatctg 220380 tagttactgt taattgttga gtttcattat ctttcatatc aacactatca ggagtaactg 220440 ttagactttt agtctttact ctagttacat taacattaac cgtcttacta atagaatcag 220500 aacttacttt aactttagca gttcctacag ctttagcagt tacaagtcca ctactattaa 220560 ctgaagcata ctcagatcct tcagtaatag agtaacttac agagtttgta gatggttgaa 220620 ttttaacgtc taactgttga gttgattctg catctatgtt aacttcttct ggagtaacag 220680 ttagactctt agtctttaaa cggcttacat taacctctac atttttagaa acatcatctg 220740 atttaactgt aacgtttgca gttccttcag aaataccagt aatatttccg ttattatcaa 220800 ctgaagtaaa ttcagaaccg tcttttaatt caaagcttac ttttcttcct tctggttcag 220860 tagtaacctc taatttctga gtttgttctg cttcaatatt aactgtctct ggagtaacag 220920 ttatactttt agtttgatta atgctttcaa attttccatc tttaggatca taaacagaat 220980 attcaatttt cttatcaatt tcgttttgta tagtttcctc atctaaaatg cggatattga 221040 aattaacaat attgtcttga atacttctct caattacttt aactaaaatt tcaccagtct 221100 tactaaagaa taataaacga tttttatctg cttgatatct agcataactt tcatcactaa 221160 catttacaga taataattgt aatagatttt ctttagctac aggagtgact tctttagtat 221220 cgaaatcttt ataacctaag attttatcta aaggtaaagc agattcttta agaacgttaa 221280 tatcttgttg caattgaaca agacgacctg taaatttacc gtattcttta actttaataa 221340 agactgaatc tttaacacgt tcaaagatgt ttttatgtcc ttcagaaata gcaatgtcgt 221400 aattttctga agcgtcttta gggaagtata atttaagttc atattcttca ttaacttcta 221460 aatcagaagt aggtaaactt aaaatttcag atttaacatc tttagcagta taagttttaa 221520 ctacagactt atctgaaagt ttgattaagt caaattttaa taatcctaat acatcacgag 221580 catctacagg attaatatag aaaggtacat taataaactt accagtttct ccttcagatt 221640 tgaagtaaac tgttcttcta tcatatttaa ttttaccagt ttcaggaaga ggttgaacat 221700 cagtaacagt ccaaccagct tgttttaagc tagctagatc attactagaa agaataacgt 221760 tttcacgagg tccacgttca cctaatccta aaaatggaat taatttttca tctaataatt 221820 ttactttaaa gtagttagta gtagccattc ttagaattca ctttcctttc tttatttttc 221880 taatagtaaa tcaattaaat cttgtttacg agcattttta ttatactcaa tttctttaga 221940 atctaattct tctttaagct cagctacagt gaattcattt aaatcttctt ctgtaacttc 222000 gacttcttca gaaccttgtt cttctacttt ttcttcgtta gtaggagctt cttcagaact 222060 ttgttcttct ttagtttctt cttttacttc gtctgatact tcgctatctg ttccttcatc 222120 cacttgcttc tcttcgctgc tgctttcatc attgctctgt tcctcttgtg attgcgtatc 222180 atttgattca gaaactgctt catttttatc ttcactctta ttttcttttt tatttgattt 222240 atcgcttgga tatacatagt cttcatcaac aattgttact tgtaaaccta aacgtctaaa 222300 taaacgaatt tgtgaacctg aagcacggaa aggtttaaca aaaggacctt tacctttacc 222360 aggcacaaat gctttttcat taataataat gaaattatta tcttcattga aatttaacat 222420 aaattagtaa tctcctttac catattttat tttataaata aaagttaagg aaggatctta 222480 taaaaatcct tcttaactaa atgttcccca tgcgttacca atacgttgtc ctttaccatt 222540 tgatttacca attggcacgt atacatattg tcctttaaat ttacctgaaa cccagataag 222600 accatcaaag tcttggattt cttcgtattt aatagagtcg ccttttttca tgaatggacc 222660 tgtaggccat ccagtccatg gaccattttt acgagtaata attcctgaag caacattaca 222720 tttgaaagta gctttttcag ttttccatag aatacctgct gaattacgtt tccatttagc 222780 agatgtaaca gctttcttag gagctgcttt cttaactact tttttcttag gagctgcttt 222840 cttagtagtt gcttttttag tagctgtact actaaaggct ggacgaatta ctccccaaaa 222900 tcctgtataa tcatggaata ctttagctgc aggtgaacca ttgctacctg cgttaaacca 222960 gttctggtca attgaataga aattgtttaa gttagctgaa gtgataatac ctgtatgacc 223020 ataaacatca tatggaggat tagcccaaat agctatatct cctggttgag gtaagaatga 223080 tggagtattt ttaataagtt tccatcctga aggcattgta ttacttttaa gatctttagc 223140 gttaccccaa ggccagaatt ttccatcagt taaataatta caataaccga tagtcaaatc 223200 catacattga gctccataag ctccatccat gtcaagtcta cgaccaatac gattattaac 223260 ccaattcaaa gcttgagttt tagttttcat attttattca aaccctttcg ataaattttc 223320 tttatttctt tatatttagt tgttctttta taaaaataat atgtttcata atagtataaa 223380 aataaatacc ctaacgaatc tttaatatga tcgttagggt atataaaatt ataatttaaa 223440 ttatagaatc atttattagc taaatgttcc ccatgctgga ccaatacgtt taccgttacc 223500 atttgattta cctactggta cgtatacata ttgtccctta aatttacctg aaacccaaat 223560 atatccgtta aaatcttgga tttcatcata tttaatagta tcacctttag acatacgagg 223620 accttgaggc catccagtcc atggaccatt tttacgagta ataattccta cagatacacc 223680 acatttgaaa gtagcttttt cagttttcca tagaatacct gctgaattac gtttccaagt 223740 agttgaagtt tcagtacttg ttttcttagg tttagcaggt gctttagttg tagtagtaga 223800 tttagttgct gttgaagttt tagctgtaga agtagcacca tttttcatat aagttagaac 223860 ctttttatct acattagaaa cactacgaga cataccgcat gcagctaata aattgcctgg 223920 atcttgtttg tctgcttgga tatcttgatg tcctggcata tttgtacttg cattaatttt 223980 atattcttta cataagaaag caagaacacg acaatagtta tcaaatgatt ttaatgaacg 224040 acttctatta gagaagtaac atccttcaac accaatagcg ccatcattag catcaatacc 224100 ataccaagaa ttatcagtag gtgtattgta cataacatgc catgcttttt catctaaagg 224160 aacacagata atacattctt tatcatcaac aaagatatga gctgatgctg tatagttcca 224220 atcaatatta tatgaattac gatagtaatc aacattattt tgggcagtag tgttagggtt 224280 tcctgtgtca tgagcaacaa taaatttagg tccgttaagc ttatctccag ctctacgagt 224340 acctattggt aaaaaatcag tataaacagg aacaccgttc catgtaccga tatgtttttt 224400 agccataatt aaattttcct ccttgaattt attactaatt aaagtaattt ctatatttaa 224460 ctgttctata tttttaatac ttgatttctg tagatacgat taatttattt tgatatcttc 224520 cacctctagt gtaaacttta ctatcagtgt cacctatatt aatactattt tcagatccat 224580 aagctataca ttcatctaag aataaattac ctcctgatga agcttggaag tcttttcctt 224640 gataactttc aaatgcgata catcctaaat tccacgattg tgtaccttca tttacatcag 224700 ctacattacc tccatcattt cttccatata taccatttat tctaatgatt tttaaacctt 224760 catgagtagt tgatccgtta tttgatttaa caccattcaa tcctttatcg gttccattat 224820 ccattcctat acaattaatc tctattatat taggtttaga accatcagca ccaatatggt 224880 aatttaaacc gtcaaaacta ttataattac ctttacagct atcaagaata atatctttac 224940 cgccaacaat agcaagacca ttgtaacttg aagcagaatg ataaaaatta catttcttaa 225000 agaatgtact gttatttgaa gttaaattta attcaatgca gtttctcccg ccatatatat 225060 ttaaattttc aaaatatata tttgaagcta aacttgttaa ctgtatattc gaagaagata 225120 ttaaaggtat tacattacta tttgaaggtt tattatcatt aatattggaa taaactttag 225180 taccgtcagt aaaccatgaa ttaggtgtac tttcaacttc atcaatacta cttactttct 225240 ttatatcaat actattatct agcgttacaa ctttatcggt agcagatcta ctaaattcat 225300 aagttctatt tttaccagaa gttagtgtcc atgaaggttc atcagccata ataatattca 225360 cattattacc tgtgcctatt atattaatgc tcttattaaa tgcttttgta attaatgtgc 225420 cgccaattct aaaatagtta ccatcagcaa ccataattgt atcattatca ttaactttag 225480 gtattactac tttaaaagat ttaaatgggt tttctttaga taaaccatca ttagaatcat 225540 taccattaac agcatctaag tagtaagtag ttccgcctga taatctatta gtagttatat 225600 catatttcac tccaaaagta ccttttccat cagtaacaat tctatttttt aatatttcat 225660 taccataatt gaaatcatta ggttttctaa ctgttattgg aagggtaggt gcataattac 225720 catcaagacc gggtaaacct tgtagacctt gagttccaat cttacctgta tcacctttta 225780 atccatttaa ctgttcttca gtaaaatcag aatactcgaa aggatctccc ttttcacctt 225840 ttaatagatc taattgttct tgagtaaaat cggaatattc aaaagggcca cctttttcac 225900 cttttaactc ggataattgt tcttgagtaa aatcagaata ctcgaaagga tctcctttta 225960 atccatttaa ctgttcttca gtaaaatcag agtatttgaa ggggtcgcct ttaggacctt 226020 gtatacctgg atcaccttta tacatctcag cattttctac catgtaattc ttaagatttt 226080 ctttgtaatc taataattta ttttcaaaat catctatttt actgttaaat gaatcttgtg 226140 ctaattttaa ttcttcagat ttatctttta taagatttaa tttttcttca actttaacta 226200 catcattttc catattctta acatagtttg tagtctcact aagtttttcc atttcatcat 226260 taagactcat tgtattgtta taattactat tgaattgttc tcttacagtt tcaaaatcag 226320 ttaaagtatc tttcatgcta cttaatttat tattcatatc ttctattgtt gaaattacat 226380 cttctttttc agattgtaaa tctaattttt tatcttcaat actatattta aaactatcta 226440 gctcactcaa atatgaatta agattatcat catcaattaa attttctttg attaagttaa 226500 gtttttctcc tgctttttca ttaatattat ttatatcagt agatattatt tttatttgtt 226560 taaaagcctc attcacttga agatatttct gttttataaa atcttcaata gagaaataat 226620 cagctacgtc atattctcca tctgaattta aatcaacata ttcattttta tttaccttta 226680 catattgaat attcattaaa tcataataat ctaatgtatt tctatcaaca taataaggtt 226740 tatttatagg tcccatacct ttacctggaa tataagtttt ttgaggaact ataattagta 226800 tactatcttc catactatat ttccactcct ttaaatttga tctgtaaaat ccccctaata 226860 tatttttaaa tcgatgatta ttctattctt ataattattg gctcatcgtt taaagttata 226920 tattagggga actaatttta gtcgaaaaaa ctaacgaaaa ttaattttta ttatataata 226980 atgttataaa ttttaaccat taataatttt aaaaatattt tcgtttaata aatctctttc 227040 taatctactt tcttcagaaa gtttttccat taattcttct tctgtatatt tatcaaaaga 227100 tacagaatta tatccattaa tagaaataga agattcatta acttgaattg atttatttac 227160 atttagatca ttaatgcttt cttctaagaa ttttttaaga cgtgtttcat ctctattagg 227220 tacattttca taggcttcaa acactatatc ttcatagtat tcttctaatg attcttcaaa 227280 accttcataa agtgaatcat ctttattttt taattggaaa ttaatatctt cttctagcaa 227340 ttctaaatta acttcttcag ataatctttc tttaacatct tcgttaactt catctaaagg 227400 attaagatag ttttctaata aacctgattc tgattcatta ttaacacgtt gaattgtatt 227460 tatattgaat tctttttcta agttttctaa agttatttca ttatctgtat aaaattcttt 227520 aagaacttta tttactttag gttcaactac aataactttc ttaaatccta aaccgaaatc 227580 aactttatca actaataatg aagaaggatt atatacttta ggaacttcat ccatataaga 227640 ttctttacta ataacgatat caacacgttt acctaaagat tcagataaag catttgtata 227700 tctaattaag tctttaattg tgtaagtttc attaacttct tcttcattaa taactttagt 227760 tttaaattca atatcagtag atccacaatt ttcacatact aattcatctt cattaacgtt 227820 aggatcaact gtttcttgaa ctccacattc gttacaaatt acttctccaa cttctttaga 227880 agtttttaaa gcttcttcaa gttctccatt acaattttca catactaatt catttgattc 227940 attcattgtt agattacttc cacaattttc acaaacagct tttccatttt caattttacc 228000 agtttcactt aaaatacgtc taacagtttc aattgattca ttagtaacga aaatttgttt 228060 ttcattttcg ttttctaatt taaatgtatt taatagagtt tcatgaattt tttctgcatg 228120 atttttaaat gatttaacta cagcgaaatc agaatcctct ctcatatata cgtatgggaa 228180 agcttgatta tttttatcat caacataatt ttcattagca attatatttt gtttttcagt 228240 attaacttct ttagattctg gagtacctat agcatatcct acttcagcag gtgtgtctaa 228300 tattccattt tttaaatcta caaaagtaaa ttcaggaact ggatctttat cgtataaata 228360 agtttcagta actgctcctc caacacttgg agaaccattt gcagcagaca aacctccatc 228420 actaacagaa cttgcattgg tatttgcatt agaagtactt actgaataag tcgcatgtgg 228480 accaaaagta gtaggaacca tcatttgaga atctaagaat ttagctctta attcagaata 228540 tcttggttgt ttcttatctt catcatcgtc ttctttttca tcttcgaata aataatcttc 228600 ttcaacagaa atttcaggat ctgaattagc tacatcagta atgataactt catctttatc 228660 agccacgatt ggttgatcgt aatcagggtg atccgaatca attacttgaa catcatcttc 228720 atcttcagca tcttcaattt catcaagatc atcagattcc tcatcatcaa tttcttcttc 228780 atcttcatta attatttcgt taaacatttc ttctaattct tcatcatctt caggaatatc 228840 acgttttaat tcttcatttt catcatcatt taaatcatct tcaaataata acatatcatt 228900 tttattttct tcagacattt ttaaatatcc tccttaaatt attttctaaa agttccttca 228960 atactatctt taataataaa taatatacac ggaagtaata cataatcttc catattcata 229020 tcatatttat catcatagta attaaacact ttacttaata ttttttcttc tatcttttca 229080 tcattcatat acattgagat taatttatat ctatcatcaa agtaagttaa acttttagtg 229140 ccttgatagt cttcattaac ttcattaatc ttagttaaat tactcaattc tataaaatcg 229200 tttaatccat ctaatacttc agtgtcttct atacttttat gaacgaagct tatttcttta 229260 tacttctctc taaacatttt taagaaatta tccttagtgt cattaagagt aataacatta 229320 ggtaaagtct ttttatcctt taatttttca tatagagaga atttatagtt cttttgattt 229380 attctttcat tcttaggatt tttatcttta taaggtagta tattagaaag ataagtacta 229440 gattttacta atagattatt gtcataaata aatctggata aattcaaatc aatatattta 229500 gttgatgcaa ctgcactaaa ttcatcttca tagtaaataa aagtatttaa tgaagaatta 229560 tagaaatgat caataaatat ttgtgaaaat tcatcagcat atttaatact atgattgact 229620 tgatagaaat cttcttctag tatcaatgat ttattatctg ttccaatatt ggaaaatact 229680 gttctatata cgtttgatac ctgattttca atatcttctg tattaacatt aaaattctga 229740 tattgtattt tatagtaagc tgagttctct agtgaactca tttctacatt agttacacga 229800 tatattctac tagttgcatt ttctttagac tgatattgaa atacaataaa atcatctggt 229860 aaaggttcaa tagtgcctgg tagtataact gcttcagatt ctaaatcttt ttcagttccc 229920 cattcttcat cccattcaat tgtaggattc atttcagcta cattatacaa agggaagtct 229980 tttaatttat tatatttcaa aggagaatta tctccaataa tttcttcaac attatctagt 230040 gaacgatcag aagtagattt ctcatgatct ttactatagt atgtaacaaa actaggagca 230100 cctgcttgaa acttactata tttttctgta ccggataaat atgaggatac gtaactattt 230160 acaatatctt ttggttgtaa ttcatcattt gatataaatg tacccatata ttctcattat 230220 cctcactttc tttattaaat ttcgtatatg gtattgttat ctttgaattt tgttttaata 230280 taataatccc aataccttaa tattatatta ataggtattg ggataaaata ttttataaaa 230340 aattaaagac caaattcttt atctaaagat tcttctaaag aactaatatc ttcattagtt 230400 tgttcttctt ctttaacagc ttcaaataag ctaaataaag cttcttcaac aggacttaca 230460 actgaatcaa ttttattttc catagcttca tttaatttag taggtaattt tttgaataga 230520 gcgatgtatt tcttttcatt atttctagcc caagcttctg cttttttagg actttggaaa 230580 gcacatactc gaataaaacg atttaaaata gatgttttac ctttagcatc aattactctg 230640 taagtaaata taactgttcc atcttcatga gcatctaaag caaattcatt ttcatcaaat 230700 tttttacctt tagcgataac tttagctttc tttttagtag cacgtgctat gaatttttcc 230760 tctgtatctt tatcagaagg gtttaccatt tttcttaatg tatccttcac attagcttca 230820 tttaataatg tttcttgtaa aaaatcttcc ataattataa ttcctacttt cgtaatttat 230880 ttttctatat aatttagttt aatttaaatt cctcatctaa tattttttct aaattttcaa 230940 taactttatc atcttcatca atttcaggtt tcttatcagg ggctttcttg aagatagata 231000 caaatttatt tccattactt tgaacccatt tttgtgcttc tttgaaacga tctgcaacta 231060 ttccaatagg tattcttcga attttatctt tacctttata tttaacaggt acttctaaag 231120 cagcgttttt accaccagta cgtttggcca ctactacaat attgcttgaa tcaattctaa 231180 taccattact tttagctttt attttaaaat tcatacaagc tttagcaaaa tccgcttcaa 231240 gcgtatcagg ttcaacaatt ccttcttgaa ctgcaacatc cgaagtatta ccgcaatctt 231300 cacatactaa ttgacctgat tcatttggag acattttaga accacattct tcacaaatag 231360 gctcttcttt atcagtatca atatcacgat ttaattcttc attaactaaa ccaaattctt 231420 tatctaaaga ttcttctaaa gatttaaaat ccattatatt ttcctcattt ctatttatat 231480 ttattaatat taatgtgtta tcttaaataa attgccctaa tgacaatttt tatcattagg 231540 acaattaaaa ttatagcata tcttttactt tacgttttaa ttctattaaa gctttattag 231600 tgaaaagcat taaataaata tcagtagtca tacgagatac gatacttaat ggagagaata 231660 tagcttcaat ttcctcgtca ggtctatatt ctgcataagg agattcatta ggaggagtaa 231720 catcagcaat aactgtttta catgctccat agaaactgat cttatcacca atactcatat 231780 catcttcata ctctgtgaag atttcaataa gtactccatc tactttctca cctttaattt 231840 tctcactatt aattttctct acagctggaa tatctacatc taatccaggt aatgtagatt 231900 tattatcttt aactgcattt ttgtattctc tatatttact tttagattta ttaatataac 231960 tattaactaa tttagctaat gtaggagaca tattttcaat atcatcatta taatagatat 232020 ttactttttt aatttctcca gtatatttag atctaacagc tctattagaa atatcttgta 232080 tttcttgttc aaattcagaa ccgattttat ctaataaaga accaatacct tcatcatcaa 232140 atgaattctc aaatatcatt aatggatctc ctgtacgtac attttgacct tctttaacaa 232200 tatattgaat atttgtatta gaagctaaat taactgtttt cttcatagta actttagttg 232260 acattgcttc agacatactg ttagaaataa tagaactatc ttcgtacgtg ccatagcttg 232320 aagcaactgc aactttagat aatttaccag cagcaaattg aatatcatta ttactgccag 232380 atcctgcaaa gtaactatca tttttagcta atacttgtcc tttattaaat ttcttaccta 232440 cttcaaattg tggagtaagt ttattatttt gatagaaacc accattggag ttcttagcaa 232500 gtttttcaga tatatcaatt acatctttat ccccattaat gtattcaaca agcattaatc 232560 ctgttttctc attgatagaa gttactttac catcttcttt agctttaaaa gcaaaagtat 232620 ctgaaatttg ataggctaaa gctttatcta caccagatcc aactaaagga cggtcatttg 232680 ttttagttgc tatcaggtgt tttgcctgag taccggtccg atatcttcaa cagagatcgt 232740 aaatctctgc cagttctctt atgaacttct ttaagatttc cttaaagtct agactatatc 232800 ttcaccctat atttttatag gggatcacta tttcgattta agggattttc acccactcca 232860 ttaacttgag ccctactcct gttggtatat ttcaataccc taagggatag tcgttgagct 232920 ttttcctaga caattttcga ttttttcttt tatttttcct tctttttgat ctttataatt 232980 tattcttatc agatctaatt tttcatgatt tttgaaataa tcatctttta ttttatcatt 233040 ctgttttaag gtttcgaatt tttctttacc atttttatat ctaaaaggta taaagtgctg 233100 ctcaccgtca aattctatac aaagattata ttcttctaaa aagaaatcaa ctcttaaatg 233160 atttcctttt atactgaaaa gatcatcaaa tttcttttct ttttcataag gtattttcat 233220 attatccaaa tattcagata tttctttagt accttttgaa ttactaatat cactacaatg 233280 aggacagcga tgtcctgatg aataaaaact ttcccaattc atcttaaatt ctcttccgca 233340 ttcttcatgt aagatatcca ttttagttct actattagaa tatgaatttg agactaattc 233400 ataatcaaat ttttctatat aatcttttac ttctttaagg tttttccttt tattaggtgc 233460 acaatgagga caaccataac cctgctgaag attactgtat gttgatttga actcattccc 233520 acataaagaa tgaaatatta ataatttctt tttactgttt tcatattcac tctttaaaat 233580 ataaacatcc ttaccatgta agtcatttaa tttttcttgt acaacttcat tatcaactac 233640 tcttcctgca cacttaggac atttataacc tttaataaaa tttgatggtg ctacatcata 233700 tacataatta cattttttat gttttagttt taatttattt ttgtataatt cgaaatcctt 233760 tatgaaaata tattcatcat aatgttttaa tctctcttta catttcttat ggtattcttc 233820 ttgtttattc aattatttcc aacctttctt acgaaaagct tgtctaggaa cttagttgct 233880 gatcatccaa tcttaatgat ttttaagcat atcacgctta ctgttaccag ttacgttgta 233940 gctcattaag ctctaaggac ttcccagcaa ttaaatgatt ttattacata tacattactg 234000 tataagggga caaaatttat ccctattctt ggactgtctg catgtctact agtatatggg 234060 tttaataatt ctaatggagt gtataaagct gtatcactta catctttttt attaccatca 234120 gtataaccac gagtagattt aatctgtgta tcatatgaaa gttgtctaac tattcccacc 234180 ttattagaat cgggagtaga tattcctaat ataccttgca tactttcgtc ataagaacga 234240 atatcaggtt catatgattg ttcagagtta cgtccagcag gacctttaaa tgtaacagaa 234300 gtcatcttat ctatttctaa gttagggttt aaatcagaaa cttcatctac tgtaggttgt 234360 tccataatag ttttaattaa ttggtcttgt ttaactgaaa tattcttagg atttttatta 234420 ttataagaat ctgaatattc tttataagca tttgccatca ttttatacaa taatgcgtta 234480 atttgctctg gtccacgtac acgataaatt cccatatcat tatgatctct agctgaaacg 234540 tcttctaaca ttgtattagc taatagtaat aattcaacca tattatcagg aagttttaaa 234600 tctcttaata cttctttagt aataggatcc attgctaaat ccatagtatt tttaatacct 234660 ttaccaacat tacgactgta gaatttatca ttgaaatatt ctaagtaagg tgtttcagtt 234720 tcaaaatcac tgaaattgta ttgtgaagta ggtaatacag ttaatccaga cattaataaa 234780 tcaaatctta atttatcagt agagtatatt aaataaccgt cttggaattt aatcttattc 234840 tttttatcat gaatgctaat tctttcattc tcagtagtaa atttataatc aacttcataa 234900 agatcaagaa tattagttaa acctttatag aaacctaata atagaattgt aggtactaat 234960 ttattagtaa ttttaacacg tgaaaatgcc atcgtcttat tagattgaat attcttactg 235020 aatttcttat caataactcc aaagtcaact tcattatcta gtttatcaat aatgtaatca 235080 aatatattta cttccataga tttaatatta gatttactac attcatacat aacagattct 235140 gttttgtctg ctaatattaa tttagattta ttaatattat acccgatagg gaaatattta 235200 tcttgatcat aatcaatctt agataaacta gcactatcag aaatcattcc taataaactt 235260 ctttggttga attcaagtac attagtgcca tcttggaaat ttaatatatt tctagataaa 235320 ctattataaa taactgaagt tacgtattta ttattaatta aagaagcatt acctttttta 235380 acagataggt tagatttatt ttcaatataa tctataactt ggtcatcttc aataactttc 235440 ttaatccatt cagtttcagc attttcttta taaccgaatt tttctataat gaatttatta 235500 tagttagttg taatccaaac agtatcaggt ttatatttaa cgattggcca catcattaac 235560 tgtttagtta atactttttt accgccatta agtttcatat atttaccgtc aataacttta 235620 ggtacatcaa atttaacatt atgagttaaa ccatctggac ttctaaattg gactttaact 235680 gtatttttta atgactgact atctgaatta tcttcaatat tcattttatt aataaatact 235740 ggaatatctt cattgtcatt aaagcttttc attatatcaa taaagtcttt attaaatgtt 235800 ttttgcatat aagaaatatc aaaatcatta gaagcaatat tgttaatagt ctcttcattg 235860 atattattaa tattttcatt aatttctcta tcgattaatt tatcttcaga aaaactaaaa 235920 tcttctaaat cattaaggta ttcatcttgt ttcttagata aagctaatat ctttttagta 235980 tttttaagag cttcatcacc aatactagat ttatttttaa tatttctctt aattgattta 236040 aatgaatcat tcttgtctaa tacgtctgaa tataaagttt cagtatcaat atcaattaaa 236100 tctttattat catttaattc tttttcaatt atcatagcta tattatattc atcatcaaca 236160 tccatttcag tattgtctaa tgatctaata taacttattg tagaatctat tttattagat 236220 attttttcta gctgttcatc attttcatat tcaacttcat cattctgagc ttcaataggg 236280 tcaattgtac ctacattatc aaatgctttc tttttaatta ctccatctac agcttcagta 236340 ttatcatcat cttcaacttt actaatttca tcagtatcca atgcctgtgt attagtgtca 236400 atcattcttc ttaatctttg tctaagtctc atattaagtt tattataatc tttgtaatca 236460 aatttaaaca ttattccatt atctaatgag acaaataata aattaacatt ttgattttca 236520 ccatgaggta attcttcttg attcttaatc atcatgaata agcttgacat gaaatctttt 236580 gtattaggtc taatagcttg ttgagaaggt ttattatacc catcaacatt aatcacataa 236640 agtaaattat tgtaatcttc tgtattattt aaagagttaa aagttgattt aactgaatct 236700 aatactgtat taaagttttt agtcattaat gatttatctt ctaaatcaat aaatttagtt 236760 gaatcaacaa tatagtttct acctttaaat aatttctcat ttcgttcaac tctatactgt 236820 ttataagatt tagatttaat ttctttttga taatctgtta tattcgttaa taatctagtt 236880 cttctatttt gagttctata caatcttggt gtatagatat tcttgaaatt ctgatgatat 236940 aataatccac tatttaagaa atcagtaaat gaattttctt taaaaccttt ataaataact 237000 aactggtctt ttttcttatc tttgatttct tcatcaatag ctttaatttt atatccagat 237060 attgaataga atttaagatt ttttaatcta ttaagatatt tcaattatgc cattcctttc 237120 cgtatttaat tttattgatt aatatattta tattactttt attttataat attattcaat 237180 aaatttccta tatacaatag ttttgattac tatcattatg tattttaatt ggatttataa 237240 aaataaaata acgaactatg tgagttattt ttaaatacat ttttatgaaa taaaaatgtg 237300 tactatcccc tcataatatt ttaatttata taaatatact ataagaatag tatatttatt 237360 attataatat tttattataa tataattata atattccgga cactttcaaa ttttttatca 237420 cataatggta caaatttata attttttaaa taattaatat aaaaatattt attaacttca 237480 tacatattgt ttaattatat aaaaattata aaatactcag taacatctaa atatcaataa 237540 aataatgaaa gaagtgaaaa taaattggct aatatgaatt atgaaaataa aacacttaat 237600 gaaaaagaag tatcgacatt attaagtgtt ggtaaagatg acattacatt agacaagtta 237660 aaagaattat ttgcttttag acaaaataca gaaccaatgt ataatccaac ggataaattt 237720 acattaaaga aagatctagt ctataataaa aaagatgaaa aaactactgt aggtagatat 237780 atatttaata aatttatttt agataataaa attggaccga ttataggcta tatgaatcgt 237840 gatatgggcg gttctggagt aggtaaactt caatctgatt tatcaaattt attacttaat 237900 gatattatta ctacacaaga aatgtcaaat tatatcgata aattacaatg gttaggtttc 237960 tctatagcca gttttattaa ttctagtcta actactacaa tgatgactgc tactgaaaaa 238020 gttaaacaga aaaaagaaga gttattagtt aaatatgaaa aagcattgaa tactcctgga 238080 gaggaattaa atgcaatatc agttattgaa aaagaattaa tcaatttaag taaagaagaa 238140 ttaaaaggtt tagctgattt agatatttat gatagtggtt cacgtggttc attcggcaat 238200 aattataaat taactgcatt aattcgtgga gcaaataaaa actttgctga tccaagtaaa 238260 attagaattg ctaaaagctc actagctgaa ggaattgatc ctaatgaact ttatatgttt 238320 ggagatatta tgactgcagg ttcagctgga cgtgcactag gtactcaaga aggagggtat 238380 caggctaagc aactaatgtc ggccttccaa acaactgttt tagataaaaa aggttctgac 238440 tgtagaacaa atcatttcct taaattaata ttagataaat caaacgcatc attaatgatg 238500 tatagatatt ttaaagataa taacgcaaga tcaggtcaat tagttttatt aactcctgaa 238560 aatgtagatg attacatggg tagagtttta gaatttagaa gtcctatgta ttgtgcaagt 238620 gaagatattt gtagtaaatg tgcaggagaa ttaccatata aattaggaat tgaaaatatt 238680 ggtctattag ttaaccaagt tgctcaagca atcgtaacaa gttcaatgaa atctttccat 238740 gatatgacga ttaaacaaaa tgaaatagat atagaaagtt atatagaata acatagatag 238800 gataacaatc attaaattga ttgttatcct tattttattg gattaaatcg ttctttaaat 238860 ttatattata attatgaggt gaatgatatg tattaatgtg atatacttat aattataaaa 238920 ataaatttaa tggagatgaa atggataatg ttaggtaaag aaataatgag aagatctgaa 238980 ataatttacg atgatacaga tataaaaact gttttaaatt tagatccgga taaagattac 239040 ataaatgaag aagaggatat cgaatatatc tgtcctaaac atggtaaaca aaaaagaaaa 239100 ataaaacaac atttagaaaa gaaaggttgt ttcgagtgtc aatacgataa taagtctaaa 239160 aagactaaag gtaaagattt attagaagag ttttacaaaa gatttagaga agatgttttt 239220 gattatccag atatagaaga agatcgtgta tattcatcta gagaagaaat aaagatagtt 239280 tgttttaaac atggagagtt cactagacaa attagagaac ataatacaaa agctaaaata 239340 tgtgataaat gtaaattaga ggatggagga aaagatttta aaaagaaaca atttgaagaa 239400 agattgagaa atgaaaatta tgaaatgtat aagattaccg atttttctga gactgtattt 239460 gaagggttaa ctaattttat gtatgttaga tgtaaaaaac atgatacgat taacaaaata 239520 caacctagat cattactaag taagaatagt aatgggtgtt caaaatgtag aagtgaaaaa 239580 ctattaaaaa gtagaagatc taataacaag gtatataacg tggaagatat ttttaacata 239640 tataaacaaa aaggaaatct tttaaatact gcgactaaat atcttgaaaa tttaaatctc 239700 gaacaaagaa aagagttatt cttaatgata tccaaacata attttggaaa taagtatgac 239760 tattctttaa tagaaaaaga aaaaaataat tttaaatcta gagataaagt aacactaata 239820 tgtaaagaac ataatgtcga atttaaacaa aatatatcac accactataa aggtaggtta 239880 ggttgtgata agtgtaaaaa ggataatgtg tctaaaagta tatctgactc atacagattt 239940 tctaaaagaa cagatataaa acctgaagaa ttaataaaag aagtggataa tgaaaatttc 240000 aaagataatg agataagaaa aatagtgaga ttaatgaatt ttgaagataa aggaaaatat 240060 tacagattat tagggaaaaa gattaaggga gataaatata actatgataa attagtgtat 240120 aacggtgata gtgttcaggt aactataaca tgtaaaaaac atggagattt taaacaggta 240180 atatacgatc actttttcca agatcataat tgtaataaat gttcaaagat cgtatccaaa 240240 caagaactta aattaagtaa tgatttggaa aaatatttta cagttaaaaa ttctttaaga 240300 agaatatttg aggataaaag aaaagaaatt gatatattta tcaaagatat taatttaggt 240360 atagagataa atggtctaag atggcattca aatgatataa aaaaggagga tgaaaataat 240420 tttgcaagat accatcaatt tagtaaaatg aatgaatctg aatgtttagg tataaaatta 240480 ttaaacttct atgacgatga aataaatata aagaaaaatg aaatttctta ttctaaaata 240540 atgaaagaaa ttttattatt taataattcc tttaatatta aaaatataga tttaaaagat 240600 ttagagatga aaaagatatc ttataatttc ataaagaaat tttataagaa acattcacta 240660 gaattcttta atgaagaaga taaaaattat agaggaatat tctataaagg ttatatagtt 240720 tccgtattct catttaataa taagaacgaa tgtcataact atagcacgaa ttacaattta 240780 aatgaagata ttgatttaat attagatgct taccctaata ccatttttaa tcttagatca 240840 gattcttata atagatataa atttcaagat tatgggttca ttacaataaa taaaactcta 240900 ccgcaatata gaaatttcaa taaaaaaggt ttaactaaaa atagatataa aagattagaa 240960 aagagggata ctaataatcc taatagaatt tatgattgtg gtagaactat catgatttac 241020 taatataata cagtgacatt aatttgtcac tgtattataa ttattttttt tttttattta 241080 ggatttataa ataactattt taatatagta atagatatat ttctatttac tatattcgta 241140 aattcttttt cttactcaat ctcgtaattt gttttgcgtc aagcaagtta catgggcctc 241200 ctacccgtat aatattgtac tacacctaag tggatcatag aaaatggtcc actttgttta 241260 tcattgtccc atagctcaac ggtagagcga tcggctgtta accggtttgt tgaaagttcg 241320 aatctttctg ggacagctta tgttcttgtt gctactggtt aaagcatatc gagtaaatcg 241380 gtattttgtg agttcgactc tcaccaagaa cacgccaata ggattaatca tccttacact 241440 aaggctgcag acttagtgtg aataaaatac agtatgagtt atatgccact cttatactgt 241500 tagattcaac taatgctaag gcatatcatt agttgtaaaa atttaaaact tatatctaat 241560 ttacgtttag ttattagatt gtatttttgt taaagaggac ttattttact taattgtaat 241620 aagtatctga ctttaactta attggttttc tagttttgac cctaacaata aaaaactaga 241680 ctattaaata ttttatttct ttttagctca caacttaaaa gaaaaactag gtggatcatt 241740 ttatgctttt ttgatcggct aaaaactaat aaagcaccct taccctaacc tcattaattt 241800 gaaggttagg gttattttat acatagtttt aaatatatat tataaaaatg agatataatt 241860 ctctcaaata cttttataat atggagatga aaaagatatg ataggttcaa agattagaaa 241920 atcattaaat gaaaaatttg gttatcatta taagttttta ttagaagatt ttaagaaaga 241980 ttatgattta aataatgata caattatggt aactaaagaa gctagtgaca tcacaaaaga 242040 atataaaata aaatcattaa agtatactaa agacattgaa aaattagaca aagactttaa 242100 gaaagaggaa gaagaattaa atattagaaa atctagaatt tttaatttag atgaattagg 242160 tttagatgaa gaccttagaa acatctgtaa gtatatagac agcactacta aattaaaagt 242220 aaaagttaga gagtataaaa aagaaagtaa agaaaatatt gaattctttt acaaaaattt 242280 tgctaattat acttataata gtgtaatata tgatatgagt cagtttaagc catcaacaat 242340 tagatctaac cagaaagtta tatgtagaaa acatggacct ttctttacca ctccagtaga 242400 tttctttata aagaaaaaag gatgtccggt gtgtgaaaaa gaaacggaag aagaaaagaa 242460 agatactagt tggaaggatg aattcataga aaataaaaat gaaaaaatat atcaagaagt 242520 aaaggaagag aaagaaaagg aaaataaaaa atctaaaaaa gaaaaggtag atgtgaaaaa 242580 agaaaataaa aaacttttag atgaagtatt aaatccacct gaattaggat attatagaga 242640 accggataag atacctaata ctgaaaaaga aaatgagaga ttcttgaaga gtattaaaga 242700 aatagatagt aaatttgaag aacctaaaga agttgaagaa ccaaaggaaa ttgttaaacc 242760 taaattaaat aaaaagacag ttgatcaaat aataggagac gataatacta atctaagcag 242820 aaaaattaga tatataaata aaaatattta tacagaaaat gaaagacaag atttctataa 242880 aaaattaact gaccgcaaac atggtaaaaa taaatataag attgataaat ttagacctaa 242940 gacgattaaa gaaaaacaag aagtaatttg tcttaagcat ggtcctttta aagtaacagc 243000 tgaagaatta ttaattaaag gtagacagtg tcctaaatgt tcttctacta gtacttccat 243060 aacagaaact tttgtaagag aatatattca gagtttagat tttgaagtta ataattatga 243120 gatagaagat ttaatcaaac cttatggtgt tgatatagtt atcgaaaatt taaaattagc 243180 tattgaagtt caaggtatta aatatcattc atctgaaaca cgatcagagg cttcaaataa 243240 atatcatcaa ttaagaaaat taaaaatgct agaaaataaa ggttatcgtt tattgaatat 243300 atacgatgat gaaattccta ataagaataa aggaattggt tgggataaat ttggtagatt 243360 cttatctgaa ttaatgatgt ttgataaaag atttgatatt gaagaaatgg atactaattc 243420 aataaaaata gatacaatta gttattacaa attcagagaa ttctttgaaa actctagaca 243480 agaatttgtt actggtgata cagaatataa aggagtggtt tataagaata aattaatttc 243540 agtattctct tataataaag aaacacgaga atgtcataac tatcatacta tgacaaataa 243600 taaatttgat ttagaattaa ttaatagaaa atacaaagat ttaaaattta tagttaaaag 243660 agattcttat gtagcgtata aaatgaaaag ccatgatatg ttaccaatag cagaaacgga 243720 acctgatttc tgtaactttt caaagactaa tggaaataga aaaaataact atataagaca 243780 aaaaagaaag gatgaaaatg ataaaaacaa agtatataac tgtggaaata taatttttgt 243840 attttaaata ataaccctaa ccttattaat ttaaggttag ggtattttat attttttttt 243900 attgaattat cttatttggt ttaacttcac ttttcatttt gatttcagtt ttaactttgt 243960 caagaacttc tgattcatat aaagaaggat cttcttcata ttttttagtc atcttcttaa 244020 cagcttctaa tttattttct aatggtgctt ctaattctac ttgattaaat aacccttcaa 244080 aattaccgaa aacaaattct tcatttaatg gaataaacag atctccattg tgtgctaact 244140 catgagcagt ataagacaaa ggtacaattc ctatattacc ctcaaaatgc attttaataa 244200 cgtcttcagc tattttaaaa ctttcatatg attttttata ctcataatta gttttaagtt 244260 tttctctgta gctagacact atatcatata aagacaatgg gtagtggtgc atttccatag 244320 ttaatcgctt atcatcattt atatcaactt ctggtataaa tttacattta gtgaggtcca 244380 tttcagtttt caaagcttta ataaatgatt tgtattcata tgagcttcta actatttttt 244440 caatatattt attaaatgtc tcttcagact ttatatcatc ttcattatta tacatttcga 244500 atttctttgt ttcatctaca tttaattcta ttgtttcgat taattttgga aggtcttttt 244560 tatctacttt tggcatttgc atagatttaa taccttcttt ccaattttct tttatctata 244620 ttaatataat taaatgttat gaatattttt tagcctttat gcgtttcatg caaattttta 244680 aatatatatt ataaaagtga agtactaatt agctaatagt atttcataaa aattacacta 244740 ggagagtgaa tcggatatga gtagaataat actaaagaaa aacaacttgt cagaagaaaa 244800 tatcagttta aaggaggtta aacgttggtt taagaaagaa atagatttta atcaaccatc 244860 taaaatgata aatgataaaa attatgtaaa taatgtaaat aatctttttg atggtgttat 244920 taatattatg aaagaaaata aaataacaga tacaatgttt agatttattt ccaatgataa 244980 taatgaagat attagaaata tttttattat ttattcaatt gatagtattc cttttgttac 245040 tagagtatat ggaccaaaaa tgaatcttaa agataaaaat agtgatgtaa atgtagatgc 245100 attactaaaa tttattaaat caagtatcat tgacaattta atgatttaca aattttataa 245160 aactacagat tttagtttcc ataaaaaact aagcagtttc ggtaattatg aaagaaatac 245220 attatacgat ttaattgctg aaattaataa agattctatt attgcagcat ataaagaatt 245280 aagtgtagat aatttaggta gttatttaat ttcattagac aatgaggagc tactaaataa 245340 atcttatgac gcaattaatt attttgattt actaatggat gctaatataa atgttagaag 245400 taaagaaggt aaattgattc aaaagattga cagaaatgat atattttcaa atagaacata 245460 ttctgaagtg ttcacattta gtcaacgttc agattattat ttcgctagta atccattatt 245520 caatattcca aaagtaagtg atgtaaggga tgatactaga gtagatttat ttatatgtac 245580 aaatggaaaa gaacaaaaaa taagagatac aagtgtctta actagagaaa atttatattt 245640 caatccattt agacaacgat tcttgtcagt tagctatgaa catcctatta gagagacatt 245700 aatatatgat ttattcttaa gtttcttcgg tatagaaaat attgaaaata ctttaaaaag 245760 atttacattt gaacttcttc aaggtgttta ttcaggaata tattctaaag ggaatgttaa 245820 tgaagttact tcaaaatcat atttattaaa ttcagaaaat aaacgtggat atactaagaa 245880 gaagaaaaat gagtatccat taaaaatgaa catatcagaa acgttaagca ctagtactca 245940 tatagtagga tatactttat tcaataactt cttatttgaa tatatacaat caagtaataa 246000 aactataaaa cttgatgatt tcaatgttat aaaattaatg aaattcatta cttttgaaaa 246060 taataacact gattttaatg aagatattaa aaatgtcttt acgtcaagaa aagatatatt 246120 taatggtaat aaacgtatta atacatcttc gcatagatat acaaatctaa aactaggttt 246180 agaatcttca ttaaatacaa tatttaatga ggataaaaat tatattgatg catttactaa 246240 tcaatatcaa aatataattg aaggaaaata tgcattttct aaacctgaaa aagaaagtat 246300 tattgaaatc aataatgaag atgaattaaa agaaatgcag gaagaaatta aatcaaaaga 246360 ttctaatata gaatatgtag aagaaactaa aaatgataaa aaagaggaga aattaaatat 246420 gtcatatcaa attattaaag aaaataaatt tactaaggat gtatcattta aatatgcagg 246480 ttctacgcat agaattgata aaattcgtaa aggtgatatt gaattagaaa ttgctaaacg 246540 taaattattc attaataaat taattaatga taatactaaa tttgctttcg tagatagcgt 246600 agagttctcg gatagtcata ctattaaagt tactaatatt gatggtgaag ttcaatttgt 246660 tagtgattat gttgatgttc ttgaaggtac agatacttta gaagaaatta gaattaaagt 246720 tactaataaa gatttagata gtgatgaaaa tttagttaaa ttaattactg gtgaagaaac 246780 tgatgttaat tctttagatg aagaaatctt agattcattc atggtttaat aaaattaata 246840 aatgctaaaa actttttagt tatctattaa aatgaagaga gttcaaatac tctcttcttt 246900 attttttttt ataactttta gggatgtgaa taagattgat agactttaaa aaaatgctta 246960 aagagaattc taggaacata gaaatttatt gtgatggagc aattaaaggt gttagatcaa 247020 aaggaactaa atatggtggt attggaatta ttccagttca agaagattta tttgattatc 247080 tatctatacc ttacatagga gaagatctaa ctaataataa attagaaatt ttggctgtac 247140 tattcactat attattctca ttagaagttt ctcaagatta taaaggtaaa acaaatatta 247200 atataaagtc tgatagtgaa tatactgttg atggatataa tacaaattta gataaatgga 247260 taaataaagg atggaaaaac tattcaggtg ctgaagttaa gaataaagaa ttatggcagt 247320 taatggaaag aattaaatat tatttaaata gaaacagaaa taagtattat gtaaatttac 247380 aatggactaa aggacatgat aatgaaaaat ataatgaatt agcagacgaa tatgcggtta 247440 aagctaaaat ggaagcatat gaagacaatg atagtgcttt ttctatagat tatgctattg 247500 ataaagctga taaatttata actaaattag aaaagaaaga ggtattgtaa atggcaacta 247560 aaatagattt taataatgaa gacgattata atgatgtatt aaatataaat gattggaaca 247620 ggctatgtat ggacttctgt attagatctg ctagtattag taaatgtgct gccaaacaag 247680 ttagttcaat tgtagctgat aaagattcta tattctctct tggagtaaat ggttcttttc 247740 cgggtaaact aaattgtaat gaaatattta aaaaagaaga tggaatttgg tacgtaaaag 247800 atcttaatga agaaactaat ttaattgaat gggttaaatg tgaagatcaa gaacaacatc 247860 ataaatggtc tttattaaat gaagttcatg ctgaaataaa tgctttatct aaaatgaata 247920 aaaaaggtat ttctactgaa gggttagact tatattgtac tcactcacca tgttataatt 247980 gtgctaaaag tataattgct gctggaatta aaaatgtcta ttttaatgaa ttatatgatg 248040 gttatgaaga tgttatggaa ttattagttt caaataatgt taacttcatt aaagtggagg 248100 tctagaatta tgtcttggtt acctctatca atatttatat ttataggaat attacttatt 248160 ttatcaacaa atgaaacaaa aagaatggta agaactgaaa aattgaaaga agaaaaagat 248220 tatttaaaaa gacaaagatt taataattta aggactagtc aaagaaagcg aggaaaaagt 248280 agatgttaga taatgtaatt atacttagtg ctttatccat agcattcttt ttaactactt 248340 taacatttat atttctaaca attcatttta gaaaagaatt agttaaaaat gttaaaatga 248400 ataaaaatta tagagataaa atagctattt tagaaaagca aacaactgga aaagatgtac 248460 tagattcatt aaattctatg atcgatgagt ttttaaaacc tacttatgat ttaactatag 248520 aagaaacata catggattta aaattagaca atcctctagt ttcaactaga aatataacta 248580 tatctgaaca aagaaaaaat gttatacttg aagatgtatt tgagaaattc atgaattatt 248640 tatccgatga ttttaaaaat aaattgtctt taatatataa ggaagatgaa atagaaaata 248700 ttgtactaga tataatgtac tataaattaa ctgtatatat taaagaacgt aacgagctac 248760 aaaaaaattc ttaaaaatat cccctaacct tattaattta aggttagggg tttatattat 248820 tttttttata ataaaacatt tattaaatct gttaaaaatc tcaattgatt tttataagat 248880 aaatcttcaa ttcttacttc ttcatcaata tcatcttcaa tatacatttc caatgtatcc 248940 atttcaatga tatatttatt ttcaattata tctttataat aaccagaagt taaattataa 249000 ttaatcatat tatctttaaa taataaaagt ttcttataca aatccatttt atctttcttt 249060 ttatcttccc aaagacactc tattaaaaat ttaaacatgt aatccatatg atgttcctta 249120 acaccatttt gataaccttt tacatctatt ttattttgat ataagtttat atagtgttct 249180 ttacctaata catttatata attatcatac tcttcacttt cagcaaatct aacatgtttt 249240 gatatcttta aattattaca tttcttacca ataacaaata tagcatcttt tttaatactt 249300 aaaatatcac tatctttaag attattattc tctataaaga tttttctagc tatcttaaaa 249360 ccattcatta aaacttcatt cattttttta ttacttctca acattttacc aataataaca 249420 tttctttcat atttctgagt atttcttaat ttattatatt gttcttcatt aagataacct 249480 gaatcatata atatattcat accagctgat ttaatatcat attcagtaat tacagtatct 249540 ttaatatatc ttacgtctga tgtgtaatta gttttcatgt ataaattaga cactgcaatt 249600 acctcctcta taatatttta ataaaccaat tactatttaa aaatacatta gctaagcaat 249660 tcatttataa tcctcctata taatcatcgc cagcctcttt actaatttca tattctctct 249720 caatatcttc ttctgattta ccttgtaatc cttctgcaac ttcaccatat tcatcaagta 249780 aaaaatctaa aaatcccatt ataaaacctc ctcaaaattg taatctaatt atcttcgtaa 249840 attttaattc ttaacaaagt tatgtttcat caatgtctta ataaattctt tattagttaa 249900 ccaatctcca gtattattaa ctacttcaag atcagttact tcatctaaat ctttcttttc 249960 tttctctaaa tcttctttat ttcttccttc acgtttaact tgattctttt cattaactac 250020 ttgaatagta ataatgtcag aatcttcacc atatttctct ttaatatctc ttacagaagc 250080 atctctacct tctctattta caataataat atttacatta taaataccat tttgcggata 250140 ttctaaactt tgatcaattg taccgtaata attttcatag aaattagtct tagctattaa 250200 attacctttc ataccatcat attcttcttt atttaagaat acataatcta ctccattttt 250260 ctcatcttct ctttgctttc tagtagttac ttgatctaat tttttaaaga ataaatgcgg 250320 atattccttt tgatctgata aattatttgc caatacagtt tttcctgaac ctgatacacc 250380 acataataag ataaattttt tcataactag aaacgacctc caaattttat tatctaatat 250440 tatttggttt tctatatttt ttagaaaaat tcgttataaa ttatgattta attccatcag 250500 attctcttaa tttatcaatt aattctataa attcattgta tttcttatct acaattttaa 250560 gataattata ttgagaatta gaagcaactt catctttttt cttttctttt aattcatcac 250620 gtttttggta gtgattattt ttacctttaa tttctattaa taaattaaaa tcaggaagat 250680 aaaaatcagg catgtagaaa tgtttcttat tagcaaacgt ataaggaata gctatattag 250740 aaggagataa tacattatta gatttaaaat ccatttgttt atctaagaat tctaagaaat 250800 ctttttcata agatccgaca tattgagtag gtaaaccttt gccagaactc caatgatatt 250860 tgcctgaaat tcttctattt tctaacattt tattttgcat ttcagggtca tttaataaag 250920 tagtcttacc gtatttttta ttcattctat ctttaaattg ttgtctatat ttatctttac 250980 atactttatc atgtacacgt tcatactttt cagtttgttc attaaattta gtaggtttac 251040 cgcatataat gcacgtacca tgagttttct tatttctgaa attaaaatat acattagctg 251100 cagataattc acctaattct ttttcatgaa atttctccat atgattataa agaccttttt 251160 tatctacata tttctttgta cagaatggac atttatgata ttttgtagcc attattaatt 251220 ttcaccgttc tttcattatc attatttaag tataaatgct tgtttctatt gttttgttat 251280 aaaaaattaa gaacgcattt atttataaat ataatattat atagtacatt aattgaaagt 251340 tggtgatagc taatcgctaa taaaaagaaa cattttagaa atgaaatatt catggctcaa 251400 aatatctata atcgtcaaca tatgttagaa gatatggaag ctatgggtca aacaatccag 251460 aatttaatta taatgaaaaa aggaacttat cctaatactc caaatttagg agtaggaata 251520 gaagattatt tatttgaaat actagataac gaaactatat ctgatattac tagtaatatt 251580 aataatcaga taagtcaata tatagtatct tcttctgtta atatagatgt taaagtaata 251640 caattaaaaa atagtaatgc aaatttaaat agtttaaaaa ttgacgttac attatcagat 251700 acaattgata tttctaacgt acaaagtttt tcttatgtgt ttgcggctaa tatgttaact 251760 aggaaaatgg taactaaact tgtcttaagc taagacttta aaaataataa aagaaaagaa 251820 tggagaaata gataaatggt aaaaaaagca gataacaatg aacttaatga ttttatgtct 251880 gaagaagaat taaatgaagt tagtcaaggt tcttctaata atgatgagaa acaagaacag 251940 aaacaaagta ctcaaaaaca acaacataat aaaaataatc aaggtaataa aaagaaaaat 252000 aacaatcgca gaagaaataa taataataaa cataatcaac aagataagaa acaaaatcaa 252060 aatagcaaat cagcaattcc aactcaaaga aacaaagaca atcaaactat gatgagtgct 252120 agtgttgata gtgataatca acaagaacaa gctaaaacag atcatatcaa tccagaaggt 252180 cctcaaccag gcgaaggttt tgttgactat gaaaacttaa cttcatatgg atttaatgaa 252240 ggaaaatcaa atgaagatac ttctagcatg acattatctg attttgaaga acaacaagaa 252300 caaaaagcta aaaaagatta tgaaaatcaa aaagctatta gtgaaattga aagtattagc 252360 agtgatgaaa gagctaatct attaaataat attaatgtag atttagataa tattgaaatt 252420 atttctgaca ttgattatga tattgataaa gaaaacacta atttcgtatt aaatagtaaa 252480 gcaactcatc aagttgtatt accacaatca gcatacattg ctcatatgga aagtttacgt 252540 aaccaagaga ttttatctat tgctgaatct attgatgatg attacaatgc aatgttaaaa 252600 cgttaccaat tatacttcca caaaatgaat acaaattcat taggaattaa taacttccaa 252660 gatttcgcta gattaacttc tgtatatgat gttagtacta ttgaatacgg attatacaat 252720 atttcattcc ctggtgaaac taaatttgat attagatgtg gtagctgtaa agctgaatta 252780 aaagacgtta aagtttctaa tgatcaatta atgtcattta aagatgaaga tgctttcgat 252840 catgttacta aaaatgttaa gaatatcact agtgttgatg aaaataaaga acactcatta 252900 atttatactg aacaacgtat tgctttaaga gattctaaaa ttatctttga aattgtaaca 252960 cctactattg aaaaacactt aagagtttta ggtagtatcc atatggacgg tttaactgaa 253020 gatgaatcag aaagatttaa acaaaatgcc acagctttaa tgcatgttaa aaatgtttat 253080 atccctgact taaaaacact taaagaagga caaaaaccta agttccgtaa attaagtgaa 253140 gataacatga aagataaaat gaaaattatt gaaaatcttt ctattcgtga tggacatcaa 253200 ttaactgatg ctatttatga tcgtgttaat aaacatgcta ttgaatatgc tattaaaggt 253260 gcaaactgtc ctaattgtgg agaagattta ggtaagattg atattgacat gagtgaaatg 253320 ctttttcggg aagcgctgca tttggtttag taacaacgac caactccaag cagtatagaa 253380 aaaaggtctt tgatgatgca gcgtatatag catatttgct tgatttattt gaaggacgtt 253440 tatcttttaa tgaaattctt aatatggaat taaatatatt aaattctatg gttaaagcca 253500 aagaaaaaga aatgaaaaat aaacgtatgc aacaacaaaa attagaatct gctcaaagaa 253560 gagattttaa taatggaatg cctaaagtag aactaccaag acatttaaat aattaaaaaa 253620 gaaatgaaag gagctgacta ttgattggtt actaatacta aagatagtca gaaaatcctt 253680 catatttatg attctcttgt tgaagatgat gataatattt tatcatctct atgtcattct 253740 aataaaggtt tagtatttgt aaatctttta tatgacctag attataaaat taaagaagga 253800 ttttctaaga actataatga atttgattac attattttgg aaacagaaga taaagaaaaa 253860 ttaaaagaaa aagtttcata tataaaaaat ttaaaatttg aagacaacaa gaatagtata 253920 agaatttcaa ttgtataaag tgaggtctaa aaagaatgtt agataagaat aaagaaaaga 253980 agaaattagt ttcaaatatt gtagatgaag attcatataa agatatagct gaattaacta 254040 ttgatactat ttcaaatacg ttaatgaaat cattaggtta tttcggatct acaactattt 254100 ttgatgatgg tattagtaga tatgtaacta aagacggtta taatatccta aaaaatatta 254160 gatttcaaga tacaatcgct acagctattt tgaattttat taaagaagta tcgttatcat 254220 tagttaaatc agtgggagat ggatcaactt catcagtaat taactcacaa gctatgttta 254280 aagaaattaa taaaagacta aaagaaaaag atgatttagg tggatattct cgtaaagaaa 254340 tttctgattc attaaataat atgaaagaat taatttctaa agaattaact tcaaaatcta 254400 ctaaaattga tcaagataat ttccataaat taaaaaatat cgctacagta tctaataaca 254460 atgatgaaaa attaggagaa atggtttatg aaattttctc taaaattggt aataaaggtt 254520 ttatattccc tgaagtttct gataatgaag aagaccatta ttcattaact agaggtattg 254580 aaacaccaca tgcattatta gataataaat taattaataa taaagatgat cattcagttg 254640 attttagtaa accttatgta gttgttgtta atgataaact aactgaagaa gatattgtat 254700 ggacatcaaa tattatttct aaaattaaac ctttctcagg acaaggatta atattctttg 254760 ctccagcttt ttctaaagag tttaaagatt atattaaaaa taatttacat gctaatagaa 254820 ataatggttc attacaagca gttgaaactg actttgaatt atctattggt tctcattatc 254880 atgatccaga aaaattagaa gatttagcta tatatacagg tggatctatt attgataaaa 254940 ctatggaaaa agaagatttc tataaacaag ttgagtctat tgtagaactt cctgaaaatg 255000 acccagaatg gttattattt aaagaaacgg taattggtag agctgaaaga attactattg 255060 ataattttaa aacacaaatt attaatggtt acggtaatgg tactcaaaaa cttaaagata 255120 gaatttcaga aattaataat gaaataactt attatactga tatgaattca gatcaagcta 255180 ttacagctat tactgattta caaaaacgag caaattcttt aaataatgct attgctaaat 255240 tatacgttgg tggttcttct caagcagaaa aaacttctag actatactta gtagaggatt 255300 cagtacatgc ttctaaatct gctttagaat acggttatgt atctggaggt aacttatcag 255360 taaataaagt tattaaaaat atcaatagag acgttttaag tgatttagat aatctgacat 255420 tagatttaat tgatatatct tcaagagaag tttatcataa agtattagaa aactttaata 255480 gatttagttc aggagaaatt gaatctatca ctcaaacttg tatagataaa gatgctatat 255540 tgaatattaa aaataatgaa tatgaagatg atgttaatac agatattatc aactcagtag 255600 aaacagatat caaaatatta gaaacaacta ttagtattat aggattgatt tcattaagta 255660 accaattctt aactaattca gtcattattc cacaataaaa cttattgccg aaaccatttg 255720 aacattaatg gtttcggctt atttttgtga atataattat cttaataatc ttttttacaa 255780 aattagattt ttatgatttt ttatttgctt ttttgctaat tttttgttat aattaaaaat 255840 atattaagca ggaggaatta tataaaattg actaatttta cagcttctca atttctcaaa 255900 aaccctacag gaaaaggttc agctacagta gctagacgtg atagaatcat attagatatg 255960 agaactagat tttcttatct ttataaaaag aatagaaaga attttaaatt aaaaatattc 256020 ttatatcaag ataaatacta tttctatttc caaatacctt cagaagatta ttttaaagag 256080 aatctatctt atgatgttat tattgaattt agaccaccta atgaaagagc agctaaagca 256140 aaagatctta ataattactt aataagattt attagtaatt cacctaactt tatgttcaca 256200 tatggttatt tatataataa agatgattta ctaataagtt ggttaagtta taaattagga 256260 cctaaagctt taaatcaacc tccagaagtt agaaacccta gacttgaata tggttttgag 256320 aaatcagttt attttgcact tttgtattta gagactaacc ctaaagcatt aaaaaatccg 256380 cttcatttga cattacctaa cagacaaaga attaaaagtt ctttcaaatc ttcagaatta 256440 aaattacgtg aatacaataa gattaaaaaa cagaaaaatg cttctaagaa aaactcatca 256500 ggtattaaaa gacaaataag taatcgtgtc gataaaagaa atgaagaaaa gaaaagagta 256560 actaaaccta ttaatagaaa agttaaacct ataggtaagg ttaaaaaagt taagaagact 256620 aactctataa aacgaaaatg atttattaaa tatatattat ataaatgata aataatactt 256680 atttatcata attattattt aaggagagtg cctgatattg gataaagtta aagaattaga 256740 gtacaaagag gatttagatt taaaaaagat tgatgaatta gttaataatg acgtggaagt 256800 acccctatta tctagtaatg tcaataagct taaaagagtc tctggtaatt ttgaattaac 256860 taatgaatac attaattcta aagacttaga tacacttgaa agaaaaaata aaaatggtaa 256920 aattgaattg gagtacatac agagaacaga tattctacca ttagttaaat ttattgaaag 256980 tgaaaagaat gatactatat ttatagattt caataagata ttagaaactg ataatcgtaa 257040 agtacctaag gatgaagagt ttgataatat atttactatt caaattaaac aaagatctta 257100 caagagtatt ttagattata ttgtaaatga tatgaatttt atagttaatg agattcctca 257160 cataatgatt aaaggtgcta ctatattaag taagatagct aaattaagag agaattataa 257220 agaagaagat ttcttcagag atattcagaa tattattgaa gatgaagatt taagaaatgt 257280 tattagaaat attgttgata ataactatac aattaattta gatcaaacta atgctgaagc 257340 tatgttacaa agtaagaaag ttattaagag agatttacag gtaactgacc aagtaaataa 257400 atcattctta tctacagctg taatgcaaag atttattatt ccgtttatta gtcaatatta 257460 tgtaactact aataagtatc attgtgaaaa ttctgatgca gataaggaaa gaactaaaaa 257520 cggttacttt aaagcattta attattgtat gtgtatttct tcattcgatt ataatgtaag 257580 taataataat aaactttata aaattgtaga acctaaagta attaaaacaa aatacaatga 257640 tagagttatt tggagattct tagatttacg ttcaattgac cctgacactg ttattaataa 257700 aataatggat aaaatcatta gacaaattgt atgtaaatta ttagtagata cttctgcagt 257760 atcttacttt acgtctgtta ttaaattctc aatcgattat gaattccagt acaaatatcc 257820 aattaagttt agatcaatac gtctatctac agatgatgac gatgatgaag atagcttcga 257880 taaattccaa atgaataact tccataaagt taatgaacgt ttagatttag ctaataaaat 257940 cactattgat agatttatta atgaacgttt agaagaatta aatattagtg atgattacat 258000 taatcgttta tatgataaat ttgattatat taatgactta caatctcatt taattaaagt 258060 ttattttgct gaatacttta acgttaatac aaatgataga aagagcattg tttcattact 258120 ggctattatg tctaaagaac ttattgataa taatatggaa actttaggaa aaatagtagc 258180 aagtaaagtt gtttcaggta caaaagctaa aaatgtaggc aaattatcat tagacgtaat 258240 tgcagataaa tattatattg ctgcttggga taaatataga tttatcaatg atattactga 258300 aaaagataac tttatcttac gtatagcatt agtaaatggt tattcattta actttactcc 258360 tgaagataaa gaagaagatg aagaagttat tgctgatatt gataagaaat actttatctc 258420 tgaagtatca caatttattt ctcaatacta aaaaaaaaat attaaaaatt acccatacac 258480 tctatattaa tgagtgtatg ggtatattat ttcttttttt cggatcatag aaaattttac 258540 ctatttaatt ctccttcaaa taaatagtct atattaatgt aagttctttc aaatatttct 258600 tcattaagtc ttttaatctc attaggatca ttaaaatcta ttatttgaga agataatata 258660 ttttgaattt tacttccatc aatttcatca actatatgag gatgattgaa tagtttaaac 258720 ctcttaatta gttcttctaa cttttcttct tttaattcat tttcaaatag ctttcttaaa 258780 gatgattcat tattatattc ttttaaagga gataatttta aatcagatat cattttatct 258840 aataatttta cagttgatac tggaccatag cttggaattg atttatattc ttgatcttta 258900 tgttccataa ataagttata taagtctaag atattataat ctatattaac aaaatcgtta 258960 atatcttttt tagtactaga gctaaataat tcgtctttaa tattctcttt agttattact 259020 ttactctttt ctgatccacg tagttctaat aataataatc tatctttata ttttaataac 259080 tgtctatata ttttatcgtt actaactatt aatgaataat catcatcatt ttcaatatta 259140 gttttagata atatataata aggtaatata gttggttcta ttttataagt gtctataaaa 259200 tatgcgttag gtatatattt aactatagtt ttaactaatt ctaaagttga tttaatagtc 259260 ttattagtat ctctataagt tatattgtct ttatccatct ttttataata ttctttctta 259320 tacccttcat caatattagt atgatatatt gactctttat ctgaatagaa taggaagaat 259380 ctactatgca tatttaatct actagcgaag aaatgtctat aatgccctat tatattaact 259440 aattcaacaa ctaaattcaa tctatcttta gtttttacgt gtgtaaaatt ttcagctatt 259500 tgaggtgaat ataattgttt aataactgaa tttaaatcta catatatagt tacattatca 259560 tttttagtat tactaccaaa tctacctcct tctacataag gtctaactaa ctcagtcatt 259620 ttgttataat ttaatttttt agagtttatt atacgttcta ttatactaat atccatatgt 259680 attccacatc ctttcattgt tataatatat aattatatat taattcgtaa ttttataaaa 259740 attgatatta cctagtaaca ttcacttata ataataagta tcgggaagtc ggtgaattaa 259800 aaattgatag aaagcttgat tactaaaaaa atatttaata taaaattaat agcattatat 259860 tcagatggaa ctactgatga tttatctcaa tttattaaaa gatctagaat agaaatgaac 259920 ttccaagaat atattatgcc atactataga tttatattaa gattgcctaa agagactata 259980 attaagatta ataaagatag agacaaagta gtattttctt tttcttcaga tatgattact 260040 actgatgctg aaagtgaaag tttatctgtc cctttttatg aagaaataat attaaaaccg 260100 ttaatggatt taagtaatcc agttaattat gatgatagag tgactagaac tgatgaagat 260160 caaaaacatt tatttgatag atatgagtta gttgctatat ctgaagaaac gttaaaaact 260220 aataaaccta tagtttcagg tatctataat aactgtactg tcagtgaagt agtcactgat 260280 ctattaagta atttaaaaaa tagagaaata tacttacacg aaatagataa taacaaaata 260340 tatgaacaga ttatattact tcctgcaaac gtatatgata atataaaatt tattgatgac 260400 gtatacggta tatataatag ggaaattaag atgtttaacc atgaaacagg attaaatatt 260460 ttaccaatgt ctggatttga tcctaatgag ataggtaaag ttaaagtaga aataagattt 260520 ccatcaaatc aaactgatga agaaatcata gaaggatctt acgagcaaat atctgaggaa 260580 gatgacttag ttagaaataa aaatatagta acaagaatta ataatgtatc tctagtagat 260640 aatacaagat tatttaatga attaatcggt tcagaaatta atttatttgg aatggataat 260700 gagacagaat acactaaatt aaatacatat cgtagagata tggaagatag aaatggacct 260760 attaataaag ttaaagtata tgacgatatt tatgataatc cttatagttt agaaaaagaa 260820 tttaataata gtaaagatat aatattaaag atacagttaa atgatatcga tttgactatg 260880 gaagatactt ttaagcaatt tgatatagag ttctttaatg aatattataa acactataac 260940 ggtttttatg aattattatc tattaatcaa gaatataaaa atgcaagtaa agctttagtc 261000 ttatcaaact atgttacatt aagaaagata actgatcata catttattaa gaatgataaa 261060 aataatccca atacctaaat gaattatagg tattgggata aattattaac cgatgtattt 261120 ttgaacatca tttaatacat ctacatgact cttcatagca ttattaatta cttttctata 261180 aagtacatta agtttattaa ggtcattaac cattctttgg ttttctctta ttttttcttc 261240 ttcaatttct ttattagcaa atttaattga agtctctgaa gcggatttca ttgtatctgc 261300 tgaaattttg aatgatttag cgaatgattt agcttcattg aattgttcaa aagatttatt 261360 aacgatataa tctaaatcaa tagacattgt taatggtatt tccaagtaat gatcgctttc 261420 ttctaattct ttttcaaagt cataatattt cattgagaaa ctatcatgac ctgcataatt 261480 taaagtattt tcatattttc ttaaattagc agctttccat atactaaata ctgaagctgg 261540 acctgaaagt ttactcatta cgttatttat ttgctcttta ttctttttaa ttttcttaag 261600 tgtagattta gttttaattg taactctgtt aaaattgtta ttaaagaatt tcataaattt 261660 aactaatcca ttcttaatta atgatagtat atttaagaaa aattctttaa cagtttgaaa 261720 gaaatcttta acaggcgatt cgtttagagt atttaattca ttattaaact ttaatgattc 261780 atttacaatt tcaatttctt cctttaagaa ttcattatta taatctttat tttctaacaa 261840 gaagaatctt tctcctttct ttattaaata aaaagaccta ataccctatt attaagagta 261900 ttaggtccta tatattatag aaatttatta tttttcagca gcagcttttt cttctttttt 261960 acctgcacta ttaatagctt tagcagcagt aaatgctgta gctaatgttt ggttagataa 262020 tttaacagct ttagatacag ctgtacgagc taatgaatgt gctttagaag catttccagc 262080 aacacgtttt ttctcagtga tagcttcttt atcaccttta gcagcagctg ttacgccttc 262140 ttttgcaaca cgttgagctt ctttattagt ttggtctact actttagcag cagctttaac 262200 ttcacgtact gaaccttcag cagcttgagc agctttagaa gcatcactaa tattagaaat 262260 agttccagaa actaaattct tttcatcagc aacacctgat ttagctcttt cgaaaccacg 262320 atcgaagttg ttaccatctg gtttagctaa ttcgtttaag tttttcaaag cagaaggtgc 262380 taataaagaa taacttttag cttcttcaag tttagcagaa gatttaactc cagcgatata 262440 ttttttaaca tttaaagtac gagcttgtaa tttgttgaat gcttcaacga agaaagcagt 262500 gaattttttg aatgcttcag cgatagcttt agcgattttg atgaagaatt ctttagcttt 262560 ttgagcgtat tcttttaatt tgctagaacc ttgttcttca cctgcaacat cgtcttcagc 262620 ttcagtaagt acattaacac tttctagaac gaaaagttct gtttgagttg cttctaattc 262680 ctcttgtaga gaaacagttt caaatgattg attttgtaac attatataat ttcctccatt 262740 tattttataa tttaaatttt ttaatatcag aaactaatat taaaatcagt ttctaattct 262800 tttcctattt ctgcatctat ttgttctgat tctgatttac cttgaacttc agctactcca 262860 gaatcaatat caattttatc agctaattta tttaaacgtt cagtagcttt attttgtttt 262920 tcacgtgatc tatctgataa atcattattt tgttcacctt caatgatttt aacagcttca 262980 cgtaaatatt cagctatatc tgaacgagtt ttaattactt taatataagc ttgttttgtt 263040 aaatataaag ctagcataga acctgcaata accattatag aaatgctgcc gtatttaata 263100 gttttttctg acatttttaa gtatttatta tctttagctt ttttagctaa atctactata 263160 tcatcaaaac taaattcttc attagcactt acaaaagagc catcaaattt aaaaatttct 263220 ttaagctttc ctgctttata catttttaaa acattttcca aagtatttac ttctaaagaa 263280 tttttatttt taagtttttt accatcaaat tgtaatttac catcttcatt actaaatcct 263340 aagaagaata attgtgaagt taataacata actgttgatg ctaaagtagt ataaacgatt 263400 tgaccaactt cattaccatt attaaaacat tttttaaagt tatttttttc tttttcaagt 263460 aagtttacag aattctcaat agtatcaaaa acggaaataa gtttagggtc aaagctatta 263520 gatttttgac tttttatgta tttaaaagtc ttttcaaaat ctttataagc tttaaccttt 263580 ttaaaatcgc ctttactaga aaggatcgat tttaaatttt tatttccaga ttttttcaac 263640 attttttcag atgttttaga gattgcaacc gaaagagctt ccattttttc ttctggttct 263700 aatcttttaa aaggtctgaa tggtaaagag aattcctgta aaactctttg tgtcattgca 263760 tcttcagtta gaagatgttt tctttcaaga agttccacag ggaatctcca cttcctttct 263820 aggagttaat ccaaatataa taaaataata aatgaaacct acacgctaat ataaattttc 263880 attttatatt ttataaattt ttgttctaaa tataatttca ttaatttatt caaattaaga 263940 aatatatctt attatataat aactgtttct attaattaac gttttaataa tttttcaagc 264000 atttctgaag ttaaatcttt ttgattattc ttaactttgt aagcaccaag tttattttct 264060 ttaataactt caaatttgtt atgatctggt aaatatttat aaactaattc cctagtttgg 264120 tctaatataa taaaatctaa taagaagaat tcattataaa ttttcttagc agctctacgg 264180 tcagataata aatccacacc agttttacgt ttaacttcat tagcttcatc aatagtaatc 264240 attaaagctg ttgttggaat atagttagct ttagctgatt tagcaattcc tgaagcttta 264300 ttaacagagt agagagaatt taatttgttc caaatagaac cagaacgtcc ttttttagag 264360 tcttgtgcaa ttttcttaac tttatcagcg tccaataata aatctttaac tagacgtaat 264420 tcacctgtag taaatttaac taatttagtt actaagtttg agccacgaga tttatcagaa 264480 agatagaaaa tgatgtcttc agttttaaca acatgaacta ctgtcttaac accgaattta 264540 gtatccttct gaatataatt tgaagctgga agaggattac catttttatc tgcaggtaca 264600 tagttaattg tagttgttat cgtagtaggt aaagaagcat ttattttttc tttatctata 264660 gtaacttttg ctccaaaatt atctctttct gcatctttaa tagtagtagt aacttgacct 264720 ttataatctt cactgaattt tctttttaat tcagaatttt tttctatagt gtcgccatta 264780 cttgatttta atctaccgtc aaatactgaa tttatatttc tattagaact ttctgacata 264840 ttattaaatt taaattcttt ctctttacca tctttaaatt caagtatttc taaattataa 264900 gttttatttg tattctttga taattcaaaa tcatttatat caaatctaat atcatatttt 264960 acaccattgg cttttactgc ataaccgcta tttgattcat ttaatagttc tttcatttct 265020 tctctagtga tagtcatatc atttaaagaa ttcatattaa atttttcttc aggagtttct 265080 aataaataat cattggatct tttaatatcc tcttttgtac tttcagctaa atttacatta 265140 ttatgcaaat cagacataaa tgaagtagga tctttcggat caaaagtttg taacggtgaa 265200 ttcgttaata caaaatcaaa ctcaaaagct ctctctaatt ctaattggtt tctcattaat 265260 tcaactgtgt cttgttctat agtatcagat gtaactaaag gaaactgtag tataaaatct 265320 ccagatcttt gctttaatga tctttttctt ttgttattat ctttatagtt tttacttata 265380 cttgtaggat ttaaatcttt taaaagacct attacatccg taaataagtt tactttattg 265440 gccaatttat atttccgcct ttctttttct tattattttt ataaagatat gtttgatcat 265500 aagaaacaat aaaaaagtaa aaaaaaaaaa taaatttaga tatcgtatca attaagacac 265560 gatatctaaa tttttatgag tgagttattt ttgaatacct atcatattcg agaagtaatt 265620 ctttatttat aattagatag tatatgttca tttataaagt tgtctactcc ataaaaatgc 265680 cctttatcat ctatttcttt tattctattc tccaaatctt taattcttct ttctaaataa 265740 tcttcatctt tattcaattt ttgaatctct ccccatttat attactacta tttaatatat 265800 gacataaata tgtgtgaacg gactagccac cttaaatata atagatatga ctgttttgat 265860 tattgaccta atgtcatttg gtaatctttt tattgtttaa ctcactctgt tcacattttg 265920 ttattttata cttccactca ttctagtata gggggatcta aaacgaatcg gcatatttat 265980 atatcttagt agaatatagt gtattaatga gaagttaatt tcttaacttc tcacctttat 266040 aatatatatt taaaaattat ttacaaaaaa aaagaagaat cttgagattc ttctttatct 266100 ataaaaattt ggattagtca tactttctcg tatttgttct acaaactcat ccttcgagtc 266160 actaatgaca cgagcttttc cttttctttt ataaggatta gaaacagaaa tcgatacatc 266220 tttttcttta gctttgaaag atatcattga gttagcttca taaaatagtt tattatgatt 266280 cattctattt atatgtcccc aactataacc atttcttttt aaataatatt tggctttttg 266340 atagtcagac attacatctt tattaaattg ttctttatct aaaccttctt ctttcataaa 266400 attatctttt ttatttttta gttctttttc tttttcatta attttacgaa tttcttcttt 266460 ctttttctct tcttctattt ttattttttg aattctttct ctttctattt cttctgcttt 266520 tttaattctt attctttctc tttctatttc ttcttcaatt tttctttgtt ttttcatttt 266580 tctatcattt ctgatttctt taattttatt taacatacta tccatccttt attattttat 266640 ttattaatta aactaataat ccttttgaaa taattatttc aaaataaatt ctatcaaatt 266700 caggttctcc ttttttatta taaattacaa atgggtattt aatatctcta atatatccat 266760 tatcaagtaa atagctattt tccagtttca tctttttaat tttcttttct aatttatttc 266820 tactaaattt tgtcaaattt aaatcaaatt tataaaattg tgtgttacct gctgtatagt 266880 aaagattttc atatttatct attgcaaata attttccagt aaatcctaca actttcttag 266940 tttttgtttt tacatcttca atatttaaat attctaattc tctaccaatg caatttaatt 267000 ctttatcagc taaatcgtta aaatctttaa tataattatc tttctcttgt tttaaaattt 267060 tatttaaatc cataaagaca tcaattttaa atttttcatc ttcaaaaagt ttaaattctc 267120 ttacactatt ttctttttca attacagtta ttcttttact catattaatc catcctttta 267180 tttttttaat ttttcttcta gttcttttat tcgtttattt aaatacatag cttcttttat 267240 agtttctatt tttacatttt ctttcctagc tttatattca actaatgaat ttgcttctaa 267300 aaatatctta taattattca ttctttttaa atcggaccaa ttaaatccat ttcttaaaag 267360 atattgttta gcttcttggt aatcaatatt ttcagatcta tcaaaatatg atttaattag 267420 accttctttt tctaagaaag cttttgttgc tttttctcta gctttccttt cagattcaac 267480 tctttcatta aatttaagaa gttcttcttt ttctctctct tcttctttaa ttcttattct 267540 ttctctttct ttttcttctt taattctttt ttcttttgct tcttttctat tttgtctaaa 267600 taatacaatt tcctctaata acattaacat tttaaataca tcctttttat ttaaattagt 267660 tgattaataa ttatcaactt cataattata atataaattt ataaattaat ttattacgga 267720 aaatctactt taacatagtc ttattaaaaa taacgattgg tggtgtaaaa gagattggct 267780 gaagataaga aaactacgga agaaaagttt aaaaaagcat taaaagaaga aggagatata 267840 aaagaaataa aatcctttaa tccatataga atgaaagata aaaactcaga gatatttaat 267900 aaaggattac cttttatttt cataacagct cctagaataa atctagtaga cgaaaatata 267960 ggaagagaaa gtttctttct ttatttaaaa tcagttaaac ctgatttatt aaaaagctta 268020 aattttagta ataatggagc cttaagctca ggtagacctt tcatcccaat cctttcaaat 268080 agatttatgg gaatatctat tcccgataca caaacaacaa tgaaagaatt tcatgaaaca 268140 ttttacggtt ataaacaaca tttaccggta ggtacagtta attcagttgc tggtggagaa 268200 atagctgtag attttgaaga gaataaagaa atagacgtta tacacttaat taaagcctgg 268260 agtgattata tagaaggtgt gactagaggt tatctattcc cttcagatga tgctaaagat 268320 aaacgttata tagattatac tagttctata tattatttct tattagactt tgatggtgaa 268380 actgtattac attattctaa gtatactgga tgtttcccta taaatgtacc ttacgatata 268440 ttctcacaaa atattggtga tgatccagaa gttcctcacg tttctattaa ctttgcttat 268500 tcatataaag aagatatgaa tcccgatata ttagttgact ttaattcagt ttcaacaatg 268560 tctactagta tagctaatgc atctggaact gaacctatta gagctaatat taataatgca 268620 actatgggta taaaattaaa ttatgatgaa atgtatccag ttaatacagg taatccttat 268680 atcgttgcag gacaaagaaa agaagacaaa gctaaaccta aatatagatt aagattttta 268740 taagagaa 268748 <210> 2 <211> 798 <212> DNA <213> Endolysin LysPALS21 <400> 2 atgaaaacta aaactcaagc tttgaattgg gttaataatc gtattggtcg tagacttgac 60 atggatggag cttatggagc tcaatgtatg gatttgacta tcggttattg taattattta 120 actgatggaa aattctggcc ttggggtaac gctaaagatc ttaaaagtaa tacaatgcct 180 tcaggatgga aacttattaa aaatactcca tcattcttac ctcaaccagg agatatagct 240 atttgggcta atcctccata tgatgtttat ggtcatacag gtattatcac ttcagctaac 300 ttaaacaatt tctattcaat tgaccagaac tggtttaacg caggtagcaa tggttcacct 360 gcagctaaag tattccatga ttatacagga ttttggggag taattcgtcc agcctttagt 420 agtacagcta ctaaaaaagc aactactaag aaagcagctc ctaagaaaaa agtagttaag 480 aaagcagctc ctaagaaagc tgttacatct gctaaatgga aacgtaattc agcaggtatt 540 ctatggaaaa ctgaaaaagc tactttcaaa tgtaatgttg cttcaggaat tattactcgt 600 aaaaatggtc catggactgg atggcctaca ggtccattca tgaaaaaagg cgactctatt 660 aaatacgaag aaatccaaga ctttgatggt cttatctggg tttcaggtaa atttaaagga 720 caatatgtat acgtgccaat tggtaaatca aatggtaaag gacaacgtat tggtaacgca 780 tggggaacat ttagttaa 798 <210> 3 <211> 265 <212> PRT <213> Endolysin LysPALS21 <400> 3 Met Lys Thr Lys Thr Gln Ala Leu Asn Trp Val Asn Asn Arg Ile Gly 1 5 10 15 Arg Arg Leu Asp Met Asp Gly Ala Tyr Gly Ala Gln Cys Met Asp Leu 20 25 30 Thr Ile Gly Tyr Cys Asn Tyr Leu Thr Asp Gly Lys Phe Trp Pro Trp 35 40 45 Gly Asn Ala Lys Asp Leu Lys Ser Asn Thr Met Pro Ser Gly Trp Lys 50 55 60 Leu Ile Lys Asn Thr Pro Ser Phe Leu Pro Gln Pro Gly Asp Ile Ala 65 70 75 80 Ile Trp Ala Asn Pro Pro Tyr Asp Val Tyr Gly His Thr Gly Ile Ile 85 90 95 Thr Ser Ala Asn Leu Asn Asn Phe Tyr Ser Ile Asp Gln Asn Trp Phe 100 105 110 Asn Ala Gly Ser Asn Gly Ser Pro Ala Ala Lys Val Phe His Asp Tyr 115 120 125 Thr Gly Phe Trp Gly Val Ile Arg Pro Ala Phe Ser Ser Thr Ala Thr 130 135 140 Lys Lys Ala Thr Thr Lys Lys Ala Ala Pro Lys Lys Lys Val Val Lys 145 150 155 160 Lys Ala Ala Pro Lys Lys Ala Val Thr Ser Ala Lys Trp Lys Arg Asn 165 170 175 Ser Ala Gly Ile Leu Trp Lys Thr Glu Lys Ala Thr Phe Lys Cys Asn 180 185 190 Val Ala Ser Gly Ile Ile Thr Arg Lys Asn Gly Pro Trp Thr Gly Trp 195 200 205 Pro Thr Gly Pro Phe Met Lys Lys Gly Asp Ser Ile Lys Tyr Glu Glu 210 215 220 Ile Gln Asp Phe Asp Gly Leu Ile Trp Val Ser Gly Lys Phe Lys Gly 225 230 235 240 Gln Tyr Val Tyr Val Pro Ile Gly Lys Ser Asn Gly Lys Gly Gln Arg 245 250 255 Ile Gly Asn Ala Trp Gly Thr Phe Ser 260 265 <210> 4 <211> 951 <212> DNA <213> Endolysin LysPALS22 <400> 4 atggctaaaa aacatatcgg tacatggaac ggtgttcctg tttatactga ttttttacca 60 ataggtactc gtagagctgg agataagctt aacggaccta aatttattgt tgctcatgac 120 acaggaaacc ctaacactac tgcccaaaat aatgttgatt actatcgtaa ttcatataat 180 attgattgga actatacagc atcagctcat atctttgttg atgataaaga atgtattatc 240 tgtgttcctt tagatgaaaa agcatggcat gttatgtaca atacacctac tgataattct 300 tggtatggta ttgatgctaa tgatggcgct attggtgttg aaggatgtta cttctctaat 360 agaagtcgtt cattaaaatc atttgataac tattgtcgtg ttcttgcttt cttatgtaaa 420 gaatataaaa ttaatgcaag tacaaatatg ccaggacatc aagatatcca agcagacaaa 480 caagatccag gcaatttatt agctgcatgc ggtatgtctc gtagtgtttc taatgtagat 540 aaaaaggttc taacttatat gaaaaatggt gctacttcta cagctaaaac ttcaacagca 600 actaaatcta ctactacaac taaagcacct gctaaaccta agaaaacaag tactgaaact 660 tcaactactt ggaaacgtaa ttcagcaggt attctatgga aaactgaaaa agctactttc 720 aaatgtggtg tatctgtagg aattattact cgtaaaaatg gtccatggac tggatggcct 780 caaggtcctc gtatgtctaa aggtgatact attaaatatg atgaaatcca agattttaac 840 ggatatattt gggtttcagg taaatttaag ggacaatatg tatacgtacc agtaggtaaa 900 tcaaatggta acggtaaacg tattggtcca gcatggggaa catttagcta a 951 <210> 5 <211> 316 <212> PRT <213> Endolysin LysPALS22 <400> 5 Met Ala Lys Lys His Ile Gly Thr Trp Asn Gly Val Pro Val Tyr Thr 1 5 10 15 Asp Phe Leu Pro Ile Gly Thr Arg Arg Ala Gly Asp Lys Leu Asn Gly 20 25 30 Pro Lys Phe Ile Val Ala His Asp Thr Gly Asn Pro Asn Thr Thr Ala 35 40 45 Gln Asn Asn Val Asp Tyr Tyr Arg Asn Ser Tyr Asn Ile Asp Trp Asn 50 55 60 Tyr Thr Ala Ser Ala His Ile Phe Val Asp Asp Lys Glu Cys Ile Ile 65 70 75 80 Cys Val Pro Leu Asp Glu Lys Ala Trp His Val Met Tyr Asn Thr Pro 85 90 95 Thr Asp Asn Ser Trp Tyr Gly Ile Asp Ala Asn Asp Gly Ala Ile Gly 100 105 110 Val Glu Gly Cys Tyr Phe Ser Asn Arg Ser Arg Ser Leu Lys Ser Phe 115 120 125 Asp Asn Tyr Cys Arg Val Leu Ala Phe Leu Cys Lys Glu Tyr Lys Ile 130 135 140 Asn Ala Ser Thr Asn Met Pro Gly His Gln Asp Ile Gln Ala Asp Lys 145 150 155 160 Gln Asp Pro Gly Asn Leu Leu Ala Ala Cys Gly Met Ser Arg Ser Val 165 170 175 Ser Asn Val Asp Lys Lys Val Leu Thr Tyr Met Lys Asn Gly Ala Thr 180 185 190 Ser Thr Ala Lys Thr Ser Thr Ala Thr Lys Ser Thr Thr Thr Thr Lys 195 200 205 Ala Pro Ala Lys Pro Lys Lys Thr Ser Thr Glu Thr Ser Thr Thr Trp 210 215 220 Lys Arg Asn Ser Ala Gly Ile Leu Trp Lys Thr Glu Lys Ala Thr Phe 225 230 235 240 Lys Cys Gly Val Ser Val Gly Ile Ile Thr Arg Lys Asn Gly Pro Trp 245 250 255 Thr Gly Trp Pro Gln Gly Pro Arg Met Ser Lys Gly Asp Thr Ile Lys 260 265 270 Tyr Asp Glu Ile Gln Asp Phe Asn Gly Tyr Ile Trp Val Ser Gly Lys 275 280 285 Phe Lys Gly Gln Tyr Val Tyr Val Pro Val Gly Lys Ser Asn Gly Asn 290 295 300 Gly Lys Arg Ile Gly Pro Ala Trp Gly Thr Phe Ser 305 310 315 SEQUENCE LISTING <110> Seoul National University R&DB Foundation <120> Jumbo bacteriophage PALS2 and its endolysins LysPALS21 and LysPALS22 from Staphylococcus aureus <130> YP-20-055 <160> 5 <170> PatentIn version 3.2 <210> 1 <211> 268748 <212> DNA <213> Bacteriophage PALS2 <400> 1 atggctataa cacagtattt ctctaacgaa caagagaaaa tagatttcct taataatgct 60 aaaatagata ctgaaagcgt tattaagata ggaagtactt catacgatgt caaagataaa 120 tggttcaata tggcaactaa gttctttgaa attgatacag aaaatactcc tatagatgaa 180 aatgaagatg aagatttaat ttcattatta aaagctggat tatttggtta tattaatgaa 240 attaattcac atgaagttaa aaacgctata tatcacagaa atgtattata cgatgaatta 300 ttcttaaata cagcttctat tcctatgtct atatacaatt ttgctaagtt gtataatgta 360 cctattcaaa tggctaaacc tgctaatttt aaagtagatt ttgttattag aaaagatgat 420 gtattaaaat taccttctaa agaaattgta tctactcaag aaatagataa aaagaaatca 480 ttaaaaactt atgagataaa attatctaaa gaccaagatt ttacaatagg tagttttaaa 540 tattgtttac cgtatgatgt atcaatggta ttaaaacaat atccaataac tagagatgga 600 aaagatgcaa tagattataa aattacagct agatatgata tagataacga tctatttaaa 660 ttttcttcta ttttagataa taatgtcaaa gtaactaaga atataataaa tggtgtagat 720 tatatgtatt tctctttaga tctatatcaa atagaaagag tttctaaaga atttaatata 780 actagcaatg atatcgctga aaatatttat ttcaatgttg gttatgaaaa tcaattgtct 840 ggttttaatg tattctatga atacttaggt acaagaacac ctatggaaac ttattttaat 900 aatactttta ctccagatac agataatcct ttctgttatt ataatttcaa agatgataat 960 tcattagaaa tttcattctc aaacatggct aattctttta gacctaaagc taatagcaaa 1020 gttattgtag aaactttaac tactaaaggt gagaaaggca actttagtta taatgataat 1080 ttaaatgtag cgttagattc taataacaca tttgaaaaag taccaataac tattcttcct 1140 aaaggtaatt cagttgatgg tcagaataga ccggatgttt atactgaaaa aagaagaata 1200 attaataaag ctattactag agataatatt attactgact ttgatattaa aaactatttt 1260 aatgatgtta atgacaataa taatattaat aattctttta ttaacttcat taaaaaacgt 1320 aatgatcttt atacacgtat gtataatgct ttcttattat taagagatag tgatagtaag 1380 gtaatgccta caaatactgc tccttatata gaacttccta aacagtattt tgagggaaat 1440 acttcattag gtaatgaaga agatggttat gtaatacctg agaacagttt attcaaatat 1500 gatcaagata gtaaaaaata cgttcacatt gaaaaaggtt tagatgatgc tgatgagaaa 1560 gaaaaatttg aaaaagataa agattcttta tattatgtaa atccttattt aattaaaatt 1620 aataaatatc ctttcttatc tactaactat tataaacttc atgtaaatga actatttact 1680 actgaatata aatacattaa tgaattaata cctaataaca ttacaactac cgatttatat 1740 gtagaaaaat taaatgactt caaaaatact ttggaatcag atacatttaa atttagttta 1800 gaaattggta tggacagttc acttcaagaa atgaaagact tattaaaagt cagagctgta 1860 ttattatctc aagaaactgg tgaaagatac ggttactttg agttgaatcc agaagaaagt 1920 attgagtctg aaaataatat tattgatgag tcagattcaa ctgtagataa atcttcttta 1980 tattcaggaa tgatatctac taatagatct ttccataatg gtaaattatc tataacggat 2040 tcactttata atgataaagg tatagtacaa gataatgtat ttatagatga aaaatttgta 2100 gtcaaagtag gattactata taaagatgaa gatatgagat atttcaatga tcttgatata 2160 tctgatgaaa tgaatttctt taaagatgaa ttccctagtc atagagatga tgaagttaga 2220 gattatacat tggcttgttc tatggaaact tttgaaggag tatctatata caaagacatg 2280 tcacacgtaa tgaatagtac agtatctatg actgatgaca gttgtaaagt agaattagtt 2340 cctttattct cattaggata ctttatgaat aattatgaag aagtttatag cgtattagaa 2400 ggatataaag aaatattaga agatgctata cctagattac aaaataacac tagtatagat 2460 atgaagcttt ataatactaa aggaccttct aataattatt atctagatac tgaattagac 2520 gatgataact taaataataa atatatctct agaacggata tattattaga tttaaatatc 2580 actctatatg cacctattaa tgatttctta gatggagaaa ttaaacgtta tatttctgat 2640 tttgtagaag catgtaatga aaaaggtgta ttacctatat ctaacttaat tagattatta 2700 gaacaaaatt tcgatataat caagtatata gtatttaatg gtatttctgg taaatatgct 2760 gaaaaagtag acaaccatta tcaaaaacta cttaatacta atataaacta tatggatcta 2820 agtaaacaag aaattattga atatgttcct gaatttatta atatcaaaaa atctcttaaa 2880 gataataagg ttgaagtgag taatgaagat tcagaggatg gaacaacggt tattgattta 2940 ggtttatctt acgatgatgt agttaatata acttattcaa tctcataaaa ataaaattat 3000 aatataaaga aagaggtata aatataatgg ctaaaacatt tatttctgat taccgcaaaa 3060 aacaagctgg tttaaataga aaagcagcta atgctttaga acagaaaaaa tacactgatc 3120 aaattaatga agaattagaa gtttcaaaag agaaagattt aattgcaggt agaaataata 3180 aattacgtgc aactaacaag aaagctattg ataatgctaa aaataaatca gaaagagaat 3240 taaaagattt aaatgcacaa actatcatga ctactttatt ctcagcatta gtatttaata 3300 ctttccctaa caaaattgct gacaaatcta aattacgtga gaaaattgtt tctaagagta 3360 gaatgttctt taacgaagca attaatgcag aattagctga ctatcaaggt agtgaagtat 3420 tctctaacgc taaatttaat gcagacgtat acactaaaga tgctcgtgga gttattgatc 3480 ctaaagactc tattaaagga gctaaagtag tatacaaaaa aggtagaact gaattcgatt 3540 acctaacaaa tgtagttgct aagaaaattg aatcagctgt aattcgtgaa tctgaattag 3600 ttgatgttcg tgaaaaatta aacgaaagct tagcagacac acataaaaag aataataaaa 3660 cactattccg tactttacat gaatcggcta tcaataatat tgtaaatgat gaagcttacc 3720 ttaatgaaga agtttcagca gaagaagtta acatggatgc tttagtagaa gctactttag 3780 attatactat tatggaatta atccatacag ctaaattgag cacatcaat atgagtgaag 3840 ttcaaaaagc tgttaagaat ggtacaatta aagttaatac taaacaaaat agtaaaataa 3900 aacctgaaaa tggttctact aaaccttcag ctgatggagt taaacctaga actattgaaa 3960 atgaaaataa accaaaatca ggttctgtta aattaaacga agaataaaaa aaaaataata 4020 taatccccct aatactaaat taatagtatt aggggaatat ttttaaaagt catcaaatat 4080 ttgacctggt tcaaatgttt tatcttcttg tgaaggtgat tgagctaatg cacttgattt 4140 aaattgatta gctatagttg acattttatt tttagcacgt tcagaatcca tagtattttc 4200 taaattagaa ccaattgatt ctacaccttt aatttcaggt gttccttcat caacagcaag 4260 tttaaatgaa ttgtcaaatg gttgagcaaa gtattcaatt ctatcttcac ccattttacc 4320 acgactagca attagtttaa atgataaatg atcgtcttga gattcatctc tagcattttc 4380 tctatttata atcataccat agtctaagtt ttctaatatc attgctgatt ctgcaatttg 4440 acttctatct aattgcttag caatatctgt tttattttca gataaagctt tttctacatt 4500 tctatatgct tctctgttta attgtgctgc tgttactaac ggtatttctt tctctttagc 4560 aaatactgta aattcgttag tgatttcacc aagtctaata cgtaaatctt caatatgatc 4620 tgaagctcta atacgtttta aatagtcttg taccatcata atcatttgat atccttgatc 4680 tgctaaattc tcatatactt catacaagta gtcagttgat acttcattat ttttcttata 4740 ttcaacaact aaactaattc ctgttttctc ataagtatat ttaattaatt catttacaca 4800 ttcttgaggt gtttgatctg actcactcat agaatatcca gtaatatatt catacatacg 4860 atctaatgat tcactcatag agttttccat agttaaataa taaactactg gttttttatt 4920 aggatctaat gattgtatgt cacttgcttt attagctagt gtaactgaca ttaacatatt 4980 taataatgta cctgatttaa atgattttgg tgtcccgaag aatgaataaa cacgaccatt 5040 ctcgaaacct ccattaatca ttttattcaa catcttataa ccagttttta atttattaga 5100 tggattacgt aatttttcaa tagaatctgc cattacttct acagcattat ctacttctaa 5160 aaagttaata aagctatttt tagcacttcc cgctccatta gaagttcttt taataacttt 5220 agtaacatct gatattggtt ctaaaacttg tttaagtaaa tcagttggat ttaatctatc 5280 catagtaatt tgatcataaa tatatttaaa tacatctgct ttttgataaa gttctaaagt 5340 agcaaatctt tctttaatat aagtattaat ttgatcaatt tctctatctg acaattgttc 5400 tatttcattt ttataatagt tatcaattgt tttaagagtt tcatataaat gactttctga 5460 catttgattt ttaaatttat cgattaaatg ttcaattaat atttctggtg attcaataga 5520 ttcttcaatt cttattttaa ctaattcttt aagaacttta attgtatctt tttgatgttg 5580 ctgcccttca tcatatacat actcttcatt aatgttctct aaaaatttat ttaacctttt 5640 taaattagtt gcattaatta atctattttc tgtaatagta tatttaacaa tttgtattaa 5700 tgtattataa ggtatactta tattagcgta atttataagt tgattatttt cattaatgta 5760 aaaactttcg ttgttttttc cttttgaatt gtctaaaaat gccataatgt caaacactct 5820 ccgttactat tatttttctt ttgttaagtt gatcaagtct tcaaaatctg gattaataat 5880 atttttaact tctttcaaat ctaattcttt atcatgtttt atagaattaa atttaacaat 5940 tgtttcaggt gtatcaagtt catcatctaa tatgaattga tacttttcat ctacttttac 6000 ttccttgata tttttgttgt taaattgaac tttgatattt ttatcagaac ttgaaatttg 6060 cttaattata tcaacgtcat ccttagaact agaaacaaat cttacataat cattttcttg 6120 acgtaactca ttgattattt ctagtttctt ttggtctgtt agctcctcat attgatccat 6180 atttatagta acgtaagttg gtgcgtcttc attttcaatt aattctacat tgtaattgtc 6240 tgtatcaaga tcattagtta caactaaaaa tcctttatct tcagtatctt taaatgaata 6300 tcttgaatat gaaccagtgt aatatacttt atctttatat tcgtgataat catgaatatg 6360 accatataca gaaacgcctt tagtaactct cattaattct tttgcttcta atattggagc 6420 tgacttaaca ggattttctg aatcatcttc atccggtaca aatgtaacaa aatcaatcat 6480 tccatgacca aatatattat catacgtatt gtcctcaact gaatatagta actcattata 6540 aaattctttc ttgtcatctg gatattcttc aggtatatat aatacattaa cttctttacc 6600 attatgctta attaactctg attctaatga attaataatt ttaaaattat catactctaa 6660 ttcgttttgg ttaaatacat caagttgatt aaaatcatgt gttttagttc ctttaatcaa 6720 tctgagtaag aaatttttat ctttagataa ttcaaacatt gtatccatga attctagaac 6780 ttctttacca gcaggttcat taaatctaat aactctatca aataaatcac ctgaaataac 6840 taccatatca atatcatcat tatctttgat gtattttaaa aaatatttat ctaattcttc 6900 tgataatttc ttaggattct ttttaccata gtgtatatca gctattacaa ctgttttaaa 6960 ttcattactc atttttatca tcctttgcta aaaagtctat catcttcata agtgtttctt 7020 ttacatattc taaacttttg taagttgctc tatcgtcttt catcattaga ttgttgaaat 7080 atatttctgg agacaaatca tctattaagt gacaacaatc aaaaccaatt attccattat 7140 tatcatacgt aattccacca tgagaataat attcaacatc tttatcataa ttatctccaa 7200 cttcaatata gccatttaaa aatcctaaat catgtctgac tataaatgct ttataacctt 7260 tatattcaaa ttcatactta ttctttctaa ctccaagtat tttatcttct ttttctataa 7320 tatgtttaag tgtatcagca tcaatcattt tgtttattca tctccattat ctcgattatc 7380 tatttccatt aatagttgca tttttctatc aaattcacca gattcaatat tttctttaat 7440 agtttctttt aatttactgt caatattttc tctattagtt ttaatgaatt caaatactgc 7500 tttagctaat tcatcatcca tactaattaa attagcttca ttattttcat caaaatctaa 7560 gtaagcaaaa gctgtagttc caaaacatgg taatccacca aacatcatga aattaatatc 7620 ttctgttgta aatctgtctt ctacttttcc aaaataagta aatgaaacta ctgaatgcat 7680 tggtgctggc attacatcca ttgttatatt ctctactggt atatccaatt cttcagccat 7740 aacctcatac atattttctt cttcaaattg gattttcttt ctagtataat tatcctcatt 7800 aggtttaata aaaacaaaat taatttccac tatccatttc atctcctgta tattagtatt 7860 ttattatatt tatatattaa ttcacatttc aaaatttctt aaccaaaatt ttttaaaatt 7920 cacacataat aatataatat taggggttag gggttaagaa ttaaaaatat ataaatatta 7980 ataattactt taatattaata tatatttaat atataaattc atttttaata aatatattta 8040 ttaaaaataa tattaataaa aaattaatta ataaatatta atgaaattta tacatgtata 8100 agaaaataat gaaaactaat aaaaaatgac tataacaatt aaatattaaa ataaaagaca 8160 gaaaaggtga aaatattgaa aacttatggt ttaaatgaat cagaattata tagacaatta 8220 aacttagatg taaatagatt tactaaacaa attaaatcag aacatttaat gggtcaagat 8280 caattagcag atacatttag tattattaaa aaccgtataa accaagcttc taaaaacgaa 8340 gtaatagata aattagagaa tggagatatt cttctactta attcaaaaga agttaaatta 8400 cctaacttta tgccagtatt aaacattcaa ggtaataaag ctttagtaaa tatcactcct 8460 tatatcaaat ctaatatgag tattaatcca aattcattat ttggtttagc tcaagcaggt 8520 ttaattata ttaaagttaa gaaagatgct aataaaatta gaaacaacgc taaattatta 8580 atttatcta gtcagattta ttctaaatta actactaaag taatggacaa actttatgca 8640 actaatatta ataaaaaaga ttctgactta atttcataca tgtttgcaaa gttcttttta 8700 gttagtatta tcggtagaac taatgatgat tcaacggaac agattgcata taaatcatgt 8760 cacaatagaa cagattttga agttattaaa gatatggaaa ataaattcga tggtcaagca 8820 tcaatgttaa acctattcag tttatttaaa gaatttaaaa aacatcctaa ctttaataaa 8880 ttttcatcaa gatcattcat tgagaacttt actaaaatgt acggagaaac ttcaatatta 8940 gctattgatc atttaccttc attctttact atgatctttt cagcttatgt aaatgcagga 9000 attaataaag aatttatcat tcttaatgca attaatgata aaattattat caactgttat 9060 agaagtttct tttaattaat tagagtcaat caacttaatc aataacagtt gattgactca 9120 tattatgaa agaaaggaga actgaagtaa tttgagtatt aaattaaata atgaactgta 9180 ttataatctc agagataaaa ctagactaag taaagtagaa aatactcaag aattagctac 9240 tggtagtttc tacacatttt ataatgattt acttttagag attagatacg ataataaaat 9300 atatgtatat acaggatatt caactcaagg agaacatgta ttagagttaa gttttcttaa 9360 agaagaatta gacaatgata ctatagaaga tgtatttatg tacgataaca tacttgtaat 9420 aattagtgaa aagggttatt acagatgttt tatggatcaa ttaacagaaa atgttaataa 9480 cacttcagct gaagttgttt acagttataa tttctataga tcaagtgaag aattaaatta 9540 tagaccttat tctttaatag atgatatgat ttgtattaaa gaagctaatg atactttagt 9600 aattagaagt attaaaacag atgcttacac taaaacaatt gtatttaata agaatattga 9660 aggttttagt ttcttatatg aaaatggttt agctatcagc ttttatggag aaccttatca 9720 tattcatgtg tatgacttta aagaagaaaa atacactcaa gattttacca ttaatgagaa 9780 tatcaatcaa tatgaatatg atatacaaca tcaaataact agaatattta aatttaaaaa 9840 ttctttatac tatgctactc gttcaggtag aatatataga agtgatatta aagataaatt 9900 aataagctca atgtcatata gattctatca atcaggttca tctattgatt atattaaatc 9960 ttatgataat tatatcactt tctctaatag aagtaataat atactaattt ataatactga 10020 ttatgataga aaagaaattc ttaaaaatga ttatttagtt aaatcattag ctataagtaa 10080 ttttattatg gtagtttctt tatatgatag tattgatgaa gattataaga aacgtattat 10140 agaaagtgga gttattcctg aagatgttaa tttaaaccca gttcataaat atgtaatgta 10200 taatccgcct agtatagaag ttttaaaaga gaaattagaa tatagatttg ataaacctga 10260 agatccattg gtatatatta accttaatat taaattagct gaaaataaat taaataattt 10320 cgatagaagt caatatcgtg ttaaatttaa tattagtcat tcagataact ctaatgtagt 10380 tgaagaatct gacgttaaaa tatataaaca gcaaggtaca gttaaaaata tgtacattaa 10440 aattggtaga aaatctcaat gggttgataa taataaatta ctctctttat tagaaaatgg 10500 agaattatta tacagattca ctatagataa tatagataac tatgtaactt tctataatat 10560 caattatcct aatataggaa gcgattttta tagacattta actgatactg aagtatttcc 10620 cgatagatct cctgagaaga gtcactatga tgctttatca gaagaattaa atattaaaga 10680 tatatttaaa ggcgctgaag atgaaaaagt tatttcatta ttatccaatt tagtaaatga 10740 gaaagttata tacccttcat ctaacttacg tattgattct gaagatatgt atttagatta 10800 tccagattat gatccaagaa gatatattga tttaagtaac gaatatccta atgggcaatt 10860 agataccaat gtaattaatt cagatgtata ttttgatggt cttaaaatat ttaaaaatga 10920 tattcttcag aaagacaatt ttgatggttc agttaacgtt tatttaaatc atttagctat 10980 gaaaaaatat atgaatgata agaattatga atatactatt catgatagaa aattatctaa 11040 acatgataat ttcattatat caaataaatc tagaagctta tatcaaacag aaaaattaat 11100 ggttaaacat acagttacta atgattatga aaaccaaaca tcattactac caactaaagg 11160 tattttatta cctaacacta gagttaatca atttaagatt caaaatatta gagtatacgt 11220 taaagtatac aatactaatg aaaatggtaa tgaatattat catagattaa atccaagaaa 11280 ctttaatctt tggattgata aagaatataa tatgcttaga gttgctgtat atggtataca 11340 aattccagaa ggttctacat taatgattat ggataacggt cttactaata atgtcatttt 11400 atatgataaa cttaattaca ttaagcgtga tattgatagt ttacctatag ttgaagttgg 11460 acctaatgga gaattattaa cggaattaaa tcgaagaact gaagatgttg aagttattgt 11520 agacggatta actttaatac ctggtaggga tttccatgta atgaacacac ctaatgatcc 11580 agatattcct tctttagttg ctttcagaaa tgttattcct aatacatcta aagtagaaat 11640 tacattatta aatgaaaatt catctgacgt atattacttt aaacgtcctg cagttgacac 11700 aactaatgta tttgtattac cagatgataa gagaatattt actaataata tatatcaaaa 11760 tgatccatat aaagatatta acttattaaa aaattctgat gaagatgtta taactaaaga 11820 aaatgtagtt aaagaatacg aattgcttga accattagag aaaaatgtag attatacatt 11880 aactatgaga ggtcaattac ctattgatat tgatcatctt aatataactt ctaatggaac 11940 tactaaatct attgccgaaa ttcaatcaaa ttcttatgat gaagatacta aaacttatca 12000 agttaaattt aaactagaag acttaggaga aggttataat actggtttag ttattagaaa 12060 aactcaagaa agtactagag atgttaaaat tgattggatt aaattgaaaa aagaatctca 12120 ttcaactaga ttatgggaat cattctctca aggtcctgaa tttaagaata aagctcttaa 12180 ctttgaggta tttgtcaata acaagaaaat tcctaataat tatgtaactg tattgaattc 12240 caaagctatt aagataagtg agatatctgg atatgcatta aataatgtaa tgattagatt 12300 taatttctct tatgatgaaa tgttacagag aatcatcgat aattataaat ataaaactat 12360 cgatgttaat gaagatagat atcatgatga tagtattgct gatattaaat ctccatttga 12420 tacattaact agtggaaaac aagctaaaac attaggtaat ttgctaatta tacaactaat 12480 caatagtggt aaaaatattc ttgattgtaa tgttgataat ctacctatag acgttaatct 12540 taatacagat attattgaaa atagttatat cagaaagaat attaatttag atatgaatag 12600 aactaatctt attaagacta ttaataaaat tagtgattat gtaaatgaaa ttcttgatgt 12660 caataaaaat aatgaaaatc tattattgaa tagtaataat cctagtttct atgtgatgaa 12720 taatagaaat ttattaaaat ctacagatga ttttaaaact aatgaattta ctgctgaatt 12780 atgggcatat agaggattta atgatgaaaa cctaaaaaac gtctttaaag atgggaaatc 12840 atatacaata ttttttgatt taacatcaat aaataaaaac actggaggag aagttaaata 12900 tcctcaatat ggtatagctt tatatgattt tgataaaaga gaaactattg ggagttcatt 12960 aataaataat atagattttc ctgaaaatga agaaaaaagt atgtctttat atgtaagtag 13020 agaaaagtat cctgataatc taggaatatt attttacact ggcgtaaatt ctactgatgg 13080 gaatgataga ataccacaag tttctagatt tagaaatatg agaatatttg aagtttatga 13140 tgacggatta tatacacctg cacctgaaga taaagttcat tctcaatatc cttattctaa 13200 aatcgatgat tacaatagat attttgaaaa taaagaaagt attaaagata ttcacattaa 13260 aaataatgat atttatttag attttaaagt agatgaatct ttattagaaa gaaataaaaa 13320 atatacattc tcattctatg ctagaaataa atctaaagaa gatgttagat ttattaatga 13380 agatttagat atgaatttct taattaaaaa agatgaattt aaagcttatg tagattatat 13440 ctttattgat gaggatatga atgtgaatga tctattatcc cgaagtaaat ttattcaaga 13500 atctgatgag aaagacattc atctagattt atttggattt aaacttgaaa agggattaaa 13560 taaaacagat tatcttccta atatcaatga tatagaaggt ggggatttac tttctaatat 13620 ctttaatata gatgaaaaag ataattcaaa cctattaagt ttgaatgaag atttcaaaat 13680 agacatgtat aataaagagg aagattatat agactttaac aatatcgata cttataatct 13740 agataatgat gaattctata cgctatcaat ggatgtaaaa gtagaagaaa taaatgatct 13800 aagtactaaa tcattatatt cgggttatat tgataaggat ggaaattata cttcagctaa 13860 aaacgtctat tatctaccat tagataaaaa taaaattaat aaaactttta gagcttattt 13920 catatattat ctaagagata ttaaaaatat taaatctttt gtagtcagat ccggttattc 13980 taaagagcaa tcttctaaaa atgatatgaa gttcagtaaa tttaaattag aaaaaggtaa 14040 aatagctact ccttattcta aagcagtaaa tactgtagaa aatattatta tagatccaga 14100 aatataatat aaattatccc aatacctttt taatatataa ttaggtattg ggattttatt 14160 aaaacatgca tttattatga aattagacga aaggagccac acttaatggt cctcatgtat 14220 ttaaacgaag aggaaaatat ttatattgaa gattacttat ataaacctat tgaaggtaaa 14280 catacattaa tagtgaaaaa tgatagaaat acgcctattg aagtaaccat taatagaaaa 14340 gttaattctt tagatattaa taaagtttat aatcatagag ttaataataa ttcttcatat 14400 gaatttgatt ttcctataga tgatactatt cctccggata tattatcttt atttatagat 14460 aaacaaaata tgacttatga aaatagtaat gatgttttaa atgtacctta tatagtccca 14520 gaaggaaatg acaatataaa cccagtagta tacaatatta gtgctaatga tagtttttct 14580 aatattagtt tagctgaaaa tatagaattt attcctgatt ctaatagtgt agacggtatt 14640 acagaaatat ggtataaatt tgataataat gaaaataatt tgccaaacta tagatcagga 14700 acactagaaa aagtaactaa agataaaata ggttctttat tatattctaa tgactttaaa 14760 tatagtgaat tatacttaca tttgttctct agagatggtt ctggcaatac ttctgaagaa 14820 aatataattc ctattgatat agaagttcct tcttttgtta ctgacggttt taaaattaac 14880 gatacagaat tatacgaagg aattgaatta gattctttca actcaaatac attatttgaa 14940 ttttctcaag ttaaaactac tagagatatt gatgtgtatt acgatataca attagtatca 15000 gttaataaag acactaaaga agaacaagtt ataggtaaag aatttaataa aacaccttat 15060 ccaggaacta ttgattttga atttacacct atcaatatag ataacgattt atatacgtat 15120 tatgtaaata taagaacttc taatgcttat ggaagaagtt taggttttgc taaatctcct 15180 aatttctcat ttaaagttaa agaagatttt aatgtagact atattgaagt ggatgaaagt 15240 cctattgtag cttttgatgc tgatggatct cctagtataa actctaaaga taagacttta 15300 gtaatagggt attctggatt caatactaga tctctatata gagagataga agttgaattt 15360 agacatagag atactagaga taaggatgtt cctgcttctc catggagaag tttaaaaaca 15420 gtgtatttag gtacagaaaa tggtgaaata caagttccat ttgatactgc tatattagat 15480 ccaaacggat ttaaaatata tgactttcaa gtatctaaaa aatattcaga agattcatat 15540 ataagaaaaa ctaaatacga tttaatggca gattcacatg tagtcaatga cgaacaaact 15600 tctaattact ttacagcgat taaaattcct acagaagtat taagaaatat gaatgttcaa 15660 gttcaagaac ttattcaagg agaaactttt acttcagaaa aaattagtat agataatgac 15720 ttaacagcac attctcgttc tagaacagat gcttacttta tagctttaaa cagatttgaa 15780 accaatataa atatgagtaa ttatgatgat atggattata tgcgtagtga gattagatct 15840 gttattaata ctaataactt taaacaagac gttaatataa ttcgtccata tgatgaaaca 15900 atggaatcat atgtagtttt tgaaagaggt aatgttgaat taaatagaga tttttgggat 15960 actaaaactt tatctaatac agattctcca tttataggcc aatataaaaa tattgaaact 16020 aatataacta catttatattgg taacgaagct agtcaaaaag taattcttaa agatgattat 16080 cgtctataca gaaagaaaaa tcttccagtt ccagaagtaa ctactagtaa aactcctgaa 16140 atagttactg aagaagatgg ttcagaatca attatattca cttcagatgt ttcaatatct 16200 tctagtaata aatatggttt agaaactgtc attgattatg aatatgatga cgatgatcct 16260 gacacgccta cagattatt tacaggatat actcaaggaa gtttattaga agatgcaggt 16320 ttctataatt tcacattaag aacatcacta acttatggtt tagaaacttt ctattcagaa 16380 cctagactat ataatttcca aattatatat gaaagtaata catttagaga acctgtattt 16440 agagagttag tgggtagtga tggtaagatt acattaacat tagaaactaa tactaatgat 16500 cctaaatatt cttataaatt tatagattct actaatgata aagatatcac atctacattt 16560 actaagtatg atacagatac tgaaaatatt aaatataaga gaaaaataga taattatggc 16620 atttatattatt ttacagtaca atatactaat ggtatatttg aagatgaatt atctactgta 16680 gtaatctttg aaaaacctat taatccagat tctagtattt caggtatatt aaattaccat 16740 aaatcaacta atactaaatt atctaaccgt tataataatg cttatctaca aactaaagtt 16800 aatgatgtcg atgatagatt ttatgtagtt gatatagatg aatcaggagc taaaagtaaa 16860 ttaattgtat cttcaggata tactatacca ttttatgatc cagctacttt aaatatgatt 16920 gaagccactg taaaacaagc caatagagat catatacatg atccaaatag taaatactca 16980 tcaataaatc caacagatgt aaatggtgca ggtcataaga tttctagtaa agattcttct 17040 aaagtagaaa gagttgatgc tgatttaact ccagataaac ctattattag attattctca 17100 gaagatccaa ttgaaggaag tttcaatgaa tatcctaaag aaaatgatac taatatagta 17160 atgggtggcg ttgagatcaa tgttactaat ggagatgcta actgggaaac agaaataatg 17220 attaatggag aaaaatttaa agatactaat actgtgtatg aagtttcagg taatcataaa 17280 attgtagcta tatttagaga tagatttaac tatacaatga attacgctac agctaatata 17340 aatattaaga aagattattt atactctcct attaatatgg atctttattc tatgaaagaa 17400 aaatatgatg tcgataagtt taatttatta ccatttggtg aagagtttac agatgaagat 17460 ctaaataaat ttgatccgac taccggatta agtggtttta caaaactttc tagtggtgaa 17520 tttggtagta tactaatggg aactgtaaca ggacaaagtt acactttatt aactttaaaa 17580 ctaagtgaat gtcctaaatt aaaaccagat accgattata tttattcagt aactatagct 17640 actccagatc aagaatttat tcaggatgaa tttcaaccag tacattacca ttggtatgat 17700 agtacttctc aagatgcaat ccaaagtaaa gaatttttag gtgtcgaaaa gattgatagc 17760 atgtttaata gagtgacgtt taaagtaaaa acggtcaaaa actttaaaac tgaaaaccca 17820 tactttagac ctttcttata taattcttct ggaaatataa atacaggttc tcatgtttat 17880 atcaagaata tgagtttaat agagtctaat aaacctaatg aaaattattt aggtaatgta 17940 agttcttatt ctaaagaaga acttgtagaa gaaaatacat ctataacttc caacggatac 18000 ttagttgatg ttaattattt ctttattact gataaagttc ttaaagatag aaatataact 18060 ggaattgatt cagaagaatc tttatgtgtc aagaaacaat atagaataaa taatggtaat 18120 tggatagatt atgatgaaaa tactagaata ttaattaaag atgtatcgac agttgaagct 18180 agaaaagtca tgatagatgg aactattatt agagaaagta tggacattac tcctgatatg 18240 ttagggtata atcttcctat tccaccagta tttattggta ctgaatataa taataaagaa 18300 gaaggatata gttatttccc tgtagttgaa aagaacatgg gtcattctta tagacttgaa 18360 ttaaatggta aaccatttga gtttggcgta ccagtattgt ctaatggatc agttcaagaa 18420 tacgagaatt atgaaataac tgcttattct aagcattata aattcccaga tagagaagct 18480 aaaaccacta ttaactttag agctatgaat aaacctcctg aaaaacctta cttaaaaggt 18540 attcaagata aagagattaa tcatattaca gataagtact tccgtttaga attaaaagaa 18600 actgaagaaa atgtacagta tatggttaaa ataaatgata gaatagttaa tattggagat 18660 tatttatttg aggaagatga ttataaactt aatggagtat tcgttataac tgttattgct 18720 aaaaataaat taggattaac ttcttataat gcatattaca ttgataataa tagaaacgtt 18780 gctgatgatt atcatgaatt cgactatgaa cgtaatgctc tgatattaaa ctctagagat 18840 aaacgttctt acgaatttaa taacgaaatg ataatggatt tacgtactgg agatatctct 18900 tatacagatg acaaaggtaa tttaattgat ataactgcta agttaaaaga aagattaaat 18960 tacgttgaat ccgatttgaa taatattaat attaattcaa tgataatgag aggaaatata 19020 tcgctattat tagatgaatt aagttatata gttaagaata atgatttctt agaaaataac 19080 cttaaagaag ctatagacaa attagaaaat gttgaaaatg aagttaaaaa ttcagataaa 19140 ctaattaagg atatagaagc tcttaagaaa cgtgttcaag aatcaaataa attggttact 19200 acactttcta aatcagtatc taagaaaact acagaaataa atagtactat taaaactatt 19260 gagagagaaa ttataagtac tctaccagtt caaagagata atatctcaat ggtagctaaa 19320 tcttattata atattaaatc agtagacttg acagctagaa ctaagattag taaaactgca 19380 tttaataact tcaagaagaa atacgaaaaa ttcttaacaa atgttaagac atatataaga 19440 aacttttaat atttgaccat acattcgaaa cttatcttta tagaaaaatt aaggataata 19500 aagagtgtat ggtctttatt attgtaaatg aaagtcggtg aaattataat tgtcttatag 19560 aatgtttatt aaaccactaa cagaaaagac tggtgcaaaa cctgaaagac atgaagttat 1920 ggttaataca gaaacaggaa tgattagttt aattaactct gatggagaaa atgtttctgg 1980 tttaaaagat ataacagttg acattgctct taaaaaagaa atattaagtt tcttagatat 197440 agttaataaa gatgtagtag agtctattaa tgatataaaa cctaaatatg aaaatgaaat 1800 gaaaagaaca gatgtaataa aggcacaaat ggataaactt aaaagtctta ataaagatat 19860 aatagaacaa atcaaaaaga tagagactaa taatgtaaca gcatacgtta tgatgcaaga 19920 tttaattaaa cagatatata atattataga tgtgtattca aagacttatt tagatatagc 19980 taaagtagaa agaaaagtag atcatttaat atacttaaga gacattctta gaaaaaatag 20040 aattcaaatg gaaaaagata ttaaatctct aactactaaa aataatgaag ttaaaaaact 20100 attggctact aaagaataca aatctactta tgatgcttgg gttgctgatt atgttaaacg 20160 tactaaagct ttatctaaag aatctaaagt aagtagtatt agctttagtc acaaaatata 20220 atataaggaa ggaggaaata cattgggtcg ttttcattat tcacctatag attataaaga 20280 ttatatgaat aaatacttta atagtcttca aacaggtgaa ttacttattg attttgaagg 20340 tgcagatata tatgtatctg aagaaggata caatatacca ataccgtcaa ataaaaaact 20400 taaagatgat attattaaat acttagaaaa tagtattgaa ggtatcaatt atagaactag 20460 agaaatacct agatttatta aacaaattga agaattaaga agaaaaatag aagaacagca 20520 ggatttaatg aaccgtcagt atgatgatat taatatgggt atagatgaca atatcaaaga 20580 tttaacttat attagtaaag taactgaaaa taatgtacag caattagggg atttaaaatt 20640 atctattgat aaaaatgatc ttaagttcat tgataaacgt ttattagagc ttgttaatga 20700 atttaactta attaatagtg attctcgtaa taaaatatat gtacaagatg ctcaaaataa 20760 atctaaacaa ctaactgcta tatggaatga aattaatgct cttatggatg atgctaataa 20820 aaaattatct aaaatgggtt ctttctcagg tactatgatg attaaacgtt cagtaactac 20880 tagaagaatg gcttatgatg cttattattc taaacgttta tttaacttta ctactaatgg 20940 tggtcatggt gatataggtt tcccatggag ttataactat gctagtaatt taagtactta 21000 tttagatttc actaaaagag ctaaaagagg tttcattaaa tggttttacg gtcaaaaata 21060 tttagactca ttaactagat taagattccc ggcttacaat ggttctggat tctggtataa 21120 aggttttgct actaaaaaag atgtacgtaa tggttctata catggtaaga gaaatccttc 21180 atgggattta tttgaaacag ttcctcttaa aggacaatta aatcaaactg atagaaataa 21240 ttttaattta ccttatataa gatcagctac aaattatact atgtttgatg cgggtaattg 21300 gtctggagaa aagaaaccta atacttataa tcatacatcc gttatagttg actctagagc 21360 tcctacttat agaataggtg gtagtcaaac gttccaaaga aacttcaaac atattggtaa 21420 aaaatatgat gtagacacta agttaataaa tcgtatagta gctaaagatg atggaactca 21480 aagaacacct agatataaat tcaataataa agatatgaat agttgtgttt ctgcaggagc 21540 acctactttc cctgttattg ttagggatat accttttata tcacatacag gtttccaaaa 21600 cagagaagga atggtaatcc gtatgggagt ttctaaatac gtatctcaaa ctgaaattag 21660 attagttaga atgaaattta ataatagtaa aggttgggta aaagcctaat taaattaagc 21720 tttcacatta acactaaaaa tattaatgaa aggacggtga atattttttg gcaagagaag 21780 gaatgactta tgaatatcct ttagaaatat cggatgaatt gatatataca aataatccag 21840 ttaatattat ggtaatggat gctcgtaacc atgctataag tttaaaagac tagatcaag 21900 ttcatagatc tataggatta aaaatgtttg cgtatcatta ttatgtaact ttaactggta 21960 taatttatgg aggaagacct gaaagagctt taaaccctga tttaactaaa ttaactaaag 22020 ctctttatac tagtatgatt agtttaaatc aaagtccttt tgaaggtata gataatatag 22080 agatgaaaga tagaacttct tccatttctt ctaataagat actaatatgt cttgaaggta 22140 acacttctta taaagatatc cctaaagctc agaaaacttc attaataaca ttatgtaaag 22200 acataatgag tagaaataga aatattaaaa atgtgtattc tatgagagaa tatttaccta 22260 tgtatgagaa tttaggagat atggtagact ttgcttctat tagatctgaa gcaacaacat 22320 caataccgcc attatttgta actactccag caggtacagt tacttatagt tttggtaaac 22380 gtgtattaag atatattgag gataacccaa tgtctggtaa tgatgttaaa ttattggaaa 22440 tatatcttaa gaaattaggt attgatgtta ttcaacccaa tggtaaatat gatgttttta 22500 ctgttgatgc tgttagaaga ttccaaaaga gatataatct tgaaataact ggttcattta 22560 agaaaaatga ctttgacgta ttaaatactg aaatcaataa agttaaattt aagaacgttg 22620 taagtgatag ctattataga ttgttatatt acagagaaga tcaagaatta tacggtaaag 22680 atatagagaa tttaaataat agactaatga aaatattccc taaacttaaa ctaaataatt 22740 attattcaga agatgctgaa aatgctgtga aaagatttca agaatttact aaattaagtg 22800 ttgacggtat tgtagggcct attacttggg aaaagatatt tagttatgaa tttactgact 22860 taactgatat aattttctat gatccgagtg ataatgaatt taaactagtt attaaaatga 22920 tacaaaataa gattaaagat aatcttaata aatttggtat aactgaatat tcaatgcatg 22980 gaatatatga tgaaataaca tataaaaata ttaagaaaat aaaatcactt ataggtttta 23040 atatctctgg aaatatagat agagaaactt atgagttttt tgtagattta taaaaataat 23100 taaaaggatg attaatatga gtaaagaaaa taaagattta tttgtattcc aagaaggatt 23160 aaatgaaatt acagatgata tggaatttgt agaatctgaa gaagaaaaac gtaaacgtaa 23220 gaaaaaagaa gaggaagaaa aagctaaaag aaaaggagat aataaataat ggcaggtaca 23280 gctcaattta ctgaaatcat taatagccat cgtgctaaat taagtactat tctttcaatc 23340 aacttaaaga gtggtaataa tatacattta aaccgaacta ttgaaggtac tttacgtatt 23400 gaaggagaat gtgtattatg ggaagagatt aaatcaggtt taagaaaatc agatcaatta 23460 gttcacatgg tatgcgatat tgaagaaatc tcacatatca gttatgtaga cggatattct 23520 gaaaaggata gagaagaaga agatattcct agagtattaa aagaaactgt tgacaatatt 23580 gtaaataata ataaagctta aaaaataagg taatggcata taatttgtca ttacctttat 23640 tatattgcca aaatttaaag caatatttaa atatatataa tattaatgaa gatagttaga 23700 tattaatatt aaagttatta ttttatatag aataataaaa acaacctcca attgatttta 23760 ttgtactaca actatataaa atagatcata tgaatacgta tgatcttaat taaaatatta 23820 cggtcattac catataattg cggatccatt gagcctaggc tttgacgaag catagagctc 23880 attggatcct atcattatat tgtcggttta atattatatt tatctatctt cttaaatttt 23940 gattattata tgaattatat tttattataa agctatatct tattaaatta agataatcat 24000 atgaatacgt atgatttaaa tttatgtatt agcaaaataa tttttccaaa attattttct 24060 tattaatag tatcgccctc tgcggggaat cttttcataa agcttcccgc agatggaatc 24120 taatcaaaca tgtttgttta taataaaata agatttttaa cttaaagttt ttctataatt 24180 aatttatagg cattatatga atacgtataa tgattattta tttatgtgta gaaatatgtc 24240 ctgatgcttg tcagcatctg ggcttatttc tcgattatat attgccagct cgtcccgctt 24300 ccttattact taggaagccg ccgagctgca atttatatat ttgttggttt aagttaaaag 24360 ttttaattcg atttaaagtt attctataat taatttatag acattatatg aatacgtata 24420 atgaaataat tatttataat cattgccata aataaatctc cacgttccag ctccttcttt 24480 aatattaaag aaggaggaac acaggatatc tatttatctt tgtttaaatc gaagttattc 24540 tctctattag ttattctata attagcttta tagacattat atgaatacgt ataatgattt 24600 tagaatcata acctattcat tatatttact ctgctttatt ttcggtgtaa tgattccttc 24660 attacactcc cagctgggac cattcttctc tcgttcgaag atcacttact ctttcatcag 24720 gtcccagcta aaataaagct ttaaatataa ttttagtatt agagaagaat atagaatgaa 24780 ttaaattcat tataataatc aactttgccg ttacctatat gattataggt aacggtattt 24840 attttttaat tttttataaa taggagatga aatggataat gtttaaattt aacaatgtag 24900 aacgtattaa cttaatagga aatagaaaaa tggattatat tgaattacaa gaatctttat 24960 atactttaaa acctaagttt aaaaagatag taaagaatga taaaggtaat tttgtattaa 25020 tattctcaga tggaagaaaa gaatatatta gtgatacaca tgtaggaagt atgtttagac 25080 ctaaaatgat ggtagttaat agtgttgatg attacaattt atctgatgga tatagacaag 25140 aatatagttt tgaaatggat ggtatagatt ctttaaatac taatttaaga agaattattg 25200 ataaaaatta tacatttaat attattactg aaaaatttag aatttatgaa gaagacaaaa 25260 tactcaattt aataaaattg aaatcaacga cagaaaatga taaagatata tttaaaattg 25320 aaggtatttt aaaaattaaa aaagatttga ttagtattga agacttagaa ttaattaaag 25380 atattttaaa tgattgttta acttcacaag aaaaatatga atattatatta aattcattag 25440 aacttttatt aaaatctata gattaaaaa atagaaatgt taatacattt gatactttct 25500 atatacctaa atcagatggt actaaaagag aaattaattc acctatagaa gaaattagac 25560 ctattcttaa aaagcaagct agtatattaa atgctatttt agatcttaga attggtaagt 25620 ataatttaga tgaaaatatt atagcttata gagatggtaa atcaattaaa gataatgcag 25680 attatcacaa agagaataaa actattatca aatttgatat tagtaaattc tttgataatt 25740 gtcattttga ttattggaaa gaaaatctat tctttagttt taaagatgaa gattatgtaa 25800 tggaaagatt tgaagaacat atgaaagatt tattatttag agaagataat aaaggattat 25860 atatgggtag tccattatca ccggcagcat ctaacttaat tatggttcca gtaatgagat 25920 atattaataa tatattaagt aaatttaaaa ctgatattaa agttactgtt tatgcagatg 25980 atataacttt ctcaagtaat gaaatcaatg atgaatttaa tcctaaaaga ttaaaaagta 26040 tggtcaatca tgcttttaaa attaatggtt taaaatttaa acttaaagaa gaaaaatcat 26100 tagtgatgaa aaatcataag agaaaaataa caggattgtc tgtaaatcat aatgatgaac 26160 cgactatcag tcaaaaaaga tatagacagt taagaactat tattcattta ttaaataatg 26220 gagtagaatt taaagatatt aaaggatttg aaacaccact acaattagta tcattaatta 26280 actactattt agatgttgat actactgaaa aagttaaaag attaatggac aataatgaaa 26340 aaatatttaa tgaattaaag aaagaagctg gggtgaatta atatgttgga tataaataaa 26400 agaaaaataa cttcagaaag tattaattta aatttaggtc tatttgaaga tttacttgaa 26460 gaaatgaatt ttggtatttt agatgatgat cattttggat tagctatta tcaattagag 26520 aatagacata tggtagaatc ttttaattat ttgaagagtg aaggtttaga agaattatta 26580 gaagatgtat tggtaaacaa taaaagtaat tcaatatata gtaccgaaag tttaattaat 26640 aatagatttc atgattatct tatgtttgtt aaaagatata atgaagataa tgaaaaagaa 26700 tcttattatta atgatttctt aaagattaat gaatataata gaattgaatt tagaatagat 26760 ttatttaaat tctcttataa aaatatatta attgatatag acatatttct gttaatatta 26820 ttcggtaaag aattctatta tgagtacaga gaaaaataca ataaatataa tataaatact 26880 aataataaaa gtttaagaaa tttaattgtt aatacttcag aaaactttag atattatgag 26940 aatgaaggag actataataa agtaatcgat aaagataaat ttgttgatta tttaaacact 27000 actattaaaa gttatatagt tactctattt agagttttcg aagatgaaaa tataattatg 27060 gatgaaagct tattatatac ttttatatat aaaatgaatt attctaaaat tagaaaattt 27120 atttatgata ttgatgatgg taatattgaa ataaaagata ttcgaagaga atataagaaa 27180 tatcttccgg aaaacatatt gatttagaac tattgtatat agaagggatg acttaattgt 27240 catcctcttc ttttaatttt tttctaattt ataacaggag cggtgaaaaa atgagtaatg 27300 tcttattaaa agaatatgaa gataatatag ataaattcct atcagataaa aacaaataca 27360 atcaagcaaa aagatatatg gtaagttaca tagaaagaaa tactaaacaa ctttcttaca 27420 atactcccat atatagaatt ccctttaata tgcaaggaat agatgttaca actattatga 27480 aattagttga tataaatccc agagagatgg aaagagaaat taaaaaatta ccattaactc 27540 gtaaatatgc tgacgtatta aaacatccat tttacattac aatgtcttta ataatcagag 27600 gaattaataa gaaattaaaa gttagaaaga atgataaaaa cttaaataat gatttaagac 27660 tatttcttct ttacttgtca ttaagttttt attggtctat ccaagttaag caatttcctt 27720 atgaacctaa tgaaaatgtg gctcagtata caattaaccg attaagtaat aaattctttt 27780 tcaaaaaata taaaactgta tcaacatcaa taactgtaac agctgagcaa aacaatatta 27840 actcacttag tatattagat aaaggtcaag atgacgatat cctagtttat ctaatggatt 27900 taagaacacg tttaaataac ttagttaaaa actttgctaa agaactttat aaagatatta 27960 atgcaggaaa ttatctaaat cctcatgtag atgtgttgga tgatgaaagt aattatagag 28020 aaggtactaa catatcagga acagttagta atatatctca aaagacacta tctgaattta 28080 cacagaaaga tattaatatg agaatattaa aaatatcttg tagtatgact aatacaaatt 28140 caaatattat gagaaacact atgagtgata ttagacaaaa tgaaattaaa aatgtcaata 28200 atttattact taatatattg acagtgtatc ttgatggtaa aaataatcct atacagtcta 28260 taggtagtca aagatttatc agagaatcaa tttctttctt tactaagagt aatactaaag 28320 ataaaagatt attggagaat aaaaaaatac ttaatgattt tttaactaaa tataatagca 28380 aatataatca aacggaaaga gaagctacta aaaatagtta cagaaaaaca atatatgtct 28440 attttgtttt actcatatca aatagctatt aaattgaaag gattgatatt aaaatgagta 28500 acaaaaatga agatagaata gaaatgtcgg aaaatattaa taatgaaaaa ataaataaaa 28560 ttggcaagag gatgaaaaaa tttaacagtg taatgaatag taatagaacg tttatctttt 28620 cggtcattgc atgtttacta cttacttctt atttcatcta ttcttttata gataataacc 28680 caagaaattc tagtgcacct tcatctaatg cagaacagca gtatacttct aaagatgatg 28740 aaagagccat gttcctaatt caagaaacaa caaataataa aattagtatg ctatctgaag 28800 tagattcttt aatatataga gatgatttat caaaaaaaga aaaattagat tttttaagag 28860 atattaaagg tttaatagag cagaataata aaaattttaa tcatgaagtt aataaatttg 28920 ataaattgtc taaagacgct gttgatgata ttaaaagtat gaataaaata aatggaataa 28980 ctgttaaata tgttgatgat gcaattaaat ttaatgaagc tcctaaagat gaaaaaccta 29040 atcatgctag ggaaatcttc caaaacaatt ccaactttag aagcattctt gctagtatga 29100 attatactaa ttatgatgat gaacaaagaa gaatggaatc aattaaagaa ggaagatctg 29160 aaaatttaaa agataaaaat aatgagagta atgacaaata atatgtcatt actctttatt 29220 taccgaattt ttaaatatat attataataa tgtatagaaa tataatttct atatgtaaat 29280 aattttatta ggagagtgaa ttggataatg gcaaatttat cagacgcatc aggtactatg 29340 catttcgaag gcttcgaagg gaaagaaaaa ttcttaaagg aaatgaaaag attaattgtt 29400 aaatcttttt cagaaaaaga aactcagtat tacattaact ttcatcatga aattgatgaa 29460 aatgatgaaa taattgtcga tgatgaacta gaagagcaat ttaatgcaat aggccgttgg 29520 tcttttggat ctagtttaga aagattcttt gatagtattt ctagtgatat agttagatac 29580 tataaacatg aagaaaattc agaggaatta attaaagata atttagatta tattaaaaat 29640 aattttgctg aagatgaaga tatggctatt agatttgagt ttactgatta tgaacctggt 29700 atgaattttc tattagaagg ttttgtagaa gtcagacctg gtaatatcat taaagatgag 29760 catgggttta ttcgttatat ggaaactgaa acatctagtg attttactga tttagaagta 29820 aatgttgaga atctagttag tgaacagatt atggataatg aagacttcat tttaccagaa 29880 gatattaatt tcattgattc tgaagcttta cctgaagaag atgatttaga tattgaagtt 29940 gatgaagatc ataaaaagat ccgaagagag ctattgagaa gatacactga agaaaattca 30000 gtattctgta ttagtgaaaa tagaatgatg gaattaaata attaaaaatt taccctaacc 30060 ttaaattaat aaggttaggg ttattatttt attaggagat gaaaaaggat atgaataaac 30120 aagaggtttt taaaaatatt gaaaaagcta tagataaata tagaaaaaat tatatgtata 30180 attggtttaa gaattattta aatgatttag aatatgaaaa agattacatt gtatatggag 30240 atataggtga tctaggtaca atagaatttt taaatagata tatcttagaa agtaatccaa 30300 taaaaaacat gaatgaaatc aatattgaag atttattaca aaaaacaact ggaagaagta 30360 atatagtttt tccttacatg gatgttttaa atgataaaat actattagat gaatttaata 30420 taacttcata tgatagaaat ctaaaaagaa ttaaattata tattaaattc aatgatgata 30480 aatatctcaa taaagttaaa aatgaagaag aaaattttag agttaattct tttagcggat 30540 attacaatat ctatagtttt gaaaaagatc taaaatcttt tcttactaat tttaaagatg 30600 ttccagattt cttagagtat attaaagata aagaagaata taagaatctt tataaatatt 30660 taaacaaatt ggagagtgaa taaaatatga ctagaataga agaaattaca acaaaacctg 30720 atttaaatag ttatatgtct gaagtattta actatcactt tgaaagaata attaataata 30780 attatgtaga aagtatagct agtaatttcg ttgatattat ggaaaatgat ataaaattta 30840 gaaatgaagg tcaaatgaat cataaagata tatttaaaga attggattca gatggtataa 30900 aaaatattaa agaaatagag tcaattttat caagatttaa aaatgaagat aataaattta 30960 ttaaaaagat tagaaaagat attaatgata aaattgatta tactaagaat aataaagata 31020 aaagaataaa aaatgtattt aaaagtaaac ataatcttcc tacgtatatc ataggtaaca 31080 ttaaattggt taatgcttca gttattattc ctagaagtaa tttattttat aaaaatgaaa 31140 atggtattaa aaatataaga atttctttta gtccggataa tttattaaca ttcaatcttc 31200 atttttcaga aatatacgga gatgaaaaag taaataaaat taagagagac tttagaaaag 31260 attattcttc ttataatgaa acacctataa gtataatgtg taaaattctc gatattgatg 31320 atgaaaaaca agttttatta gaatataaat ttgatttaga caatatatat tataatatga 31380 caactgaatc taaaaataat ttaaacgaaa tgtctgattt aatgaattcc gttatcaatt 31440 atcaaatcca aataaagaat aaaaatttaa aaagtaccaa agtaattgaa attattaaaa 31500 ataatagtat catgagaaaa ttacaattgg attatgaatc taacaatgag aataaatatg 31560 aaatggaacc tattcctaga caccttaaaa aattattcgg taaaggagag aaataattat 31620 ggttaaaaaa atagattgga agtatactat aacaaagaaa tacttagagg atgttaaaga 31680 tctatatgat aaatttttag atagattcat taaaatatat aaaaatagtg ttgacaaaga 31740 tcaaaaaatt gaattagcta ataaaaatca tttctatatg gatattgaaa ttatttatga 31800 tcttatgaat gaaataaata atgaagaaga tataaaagat tttaaagaaa ttgctgattt 31860 tattaatgat aatcgatcag aatttatgag catttcagat tttaaaaata attctgaaac 31920 tttggattct atttatcata tgattgcaga ttataatgat ctctacaaag aacctaaaga 31980 aatattagaa attaaaaaat taattggtag taattcttta gattatatta ataatttaga 32040 tagagaaaat ttaattaatt taatagttga taaaagatt ggaaatacgg tttttttcaa 32100 ggatattgaa ttaaagagat tagttaataa ttttagaggt tattctttat atgataaaat 32160 attaaaaaat tctttattag gtttaatatc taaaggtgtt ttttcaaaaa gtattaaagt 32220 tcattttaat aatttaagag atgaaaataa taatctagat attgttagaa ttccagattt 32280 aagaataaat gataaagaat taaaaaatat ttctgatgat attgttgaga tacatcaatc 32340 atatcaattc ttattaaatg aacttaaaat taaaactgtt aaaaatttca atgaatttat 32400 taaagaaaaa ttaccaaatt taaaagtaga agaatttgaa atatcttcaa aagatttact 32460 aactgaagaa aaaattaaaa gtgaatatcc tagtctagat aaagatctta gaaaaataga 32520 caatattatt aagcaaatgg aattagttta aattatatcc catacctcta tttaaagggt 32580 atggggtatt ttattatttt tattatagga gagtgaaatg gataatgagt aaagaaatat 32640 ggaaaagaca cccaaaattt aatttattaa taagtgataa aggtagattt tataacgaaa 32700 gtaaagggta tatacacgta catgaatcaa gtaagcatgt aaacaatttg tgttatatat 32760 atttcgattc aaatactata aactgtgcta aagctatttt agagactttt agggaacaga 32820 aagatgaata ttataataaa atatacttta aagatggaaa tagagataat cttaacttag 32880 ataatcttga atggacttta ataacaggta gggatcctaa attaattgaa ggtattttag 32940 aagatattaa aaataaaaaa catgtggatg atatattaga aaaatataac tacgtatata 33000 gtgtaaaaac tatttattac ttaaaaaata attatttaaa agctcatgaa aaagctatag 33060 aatttgatga atctaaagaa aaatggaaac agactgaaga gaataaaaat attcttatta 33120 gtaactatgg aagattatac aataagaaaa ctaactatat tatgaaaggt agacgtaatg 33180 ctgataatga aaaagttact tattatttta ttgataatac ttcaagtgga gattatgaac 33240 atttttcagc attaaggtta gttgctaaat atttcgtaga caatccttat aatttacatt 33300 atatttataa tagaaataat gtatctagtt tttattataa agatttagaa tatactctaa 33360 acagtaaatt tactttgaaa gtttgtatgg agatgattaa aagattttta attaatgaag 33420 aaaaacctag tgtcatctct aaagactttg agatacatta tagtactttt aaaagtattt 33480 taaaagagta taataaaaga tcaatcgatg tatatgaata ttttggcata gaaaaagaaa 33540 atgaaatatg gaaagattat gatgaaatac tatcggttag taataaaggt agattctata 33600 ataaagaaag aaaagctttc attgagaaga aatttcgtga tggatttctt actattaatt 33660 acaataaaaa taatcatggt gcttcaaaac tagttgctag aacattttta ggtatagaga 33720 aaaaaccttt tgataaaatt atttataaag atggaaatgg taaaaatatt aatgttgaaa 33780 atatagaatg gtctttattc aaaaatcttt cattaaaaga ttgtaaagag ataaaagatc 33840 ttaaagattt aggtacttca gatgcaaaaa taattagaca atataaaact tcaccgggta 33900 ctataaataa aataatgaat tattataagg aaggtgtttt aagtgataaa aaataaatat 33960 tataaagcag ttttatctaa taaattatct aaagaaaatg atcctagata tgtaatagta 34020 gataaaaata ataaagtatt agatgattcc aaaggtaatg gatacactac gaaacagaaa 34080 gcttatcgag gttattcatt taaacaaaag aataatgaag aaattaaaaa gaaagctatt 34140 aagaacagtc aagataaaca agctattaaa aatgagatta aaagatttct aaaagaaaat 34200 cctgaagttg aaagggatat ttttaatctc gaatttcaat acaaatcaat gggatatgat 34260 tagatgaac aagacttgaa agaaatatta gaaggtaatt tattatcttt caataaatta 34320 ttttttgatt ccaaacaact attagattat ctatctaaat aaaaaagaga aggaatgaag 34380 ttaaatgtca agtaattatt caggcagtaa tattaaacat ttagaaggat tagaagcggt 34440 aagacaccgt agtgatatgt acgttggtgc aattgatggt gctttattcc atatgactaa 34500 agaaattcta gataactcag ttgatgagtt catcaatgat tatggaacta aagtagtaat 34560 tgatttagat ttacaaaaag aaattatcac tattaaagat gacggtcgtg gtttacctac 34620 tgatattcat ccagaaaaga aaatacctac aattgagtta ttatttacat ctttacactc 34680 gtcaggtaaa tttgataaga atgcatttaa agtgtctgca ggtaaaaatg gtgtaggtgc 34740 atctgtagta aatgcattaa gttcatatat gatggtaaaa tctattcgtg aaggttatga 34800 atactatatt gaatttgaaa atggaggtaa aattaaaact ccatttaaga aagttaaaac 34860 taaatatcct aagagttatt caggtacaga agttacattt aaaccagatt ctgaagtact 34920 taaagaatac gttaagttcg ataaagatca aattagagat aatttaattc aaagagctta 34980 ttgtaatgct gacttgagaa ttgaatataa tgtaattgat gaagatggta aaaagaaaaa 35040 tgaagtattt cacttcccag aaggaattga agctttagtt aaagatgaaa ctaataaacg 35100 tctaactcaa gtatatcact ttgaaaaaga aattgatggt gatgtttatg aggtagcttt 35160 aacttacact aatacagata aagaagagat tgtttcattt gttaatggta ttcaaacagc 35220 tcgtggtact catgaacagg gtttaaagac tggtattacc actattatta ataaatttat 35280 tattgataat aacttattaa ctaaaggtat agataaatca tcaattactg gtgacgatgt 35340 tcgtgctggt ttatttgctg ttattaactg taagttaagt aatccaactt atagatctca 35400 aacaaaggat gattaagta acccagaagc gaatagtaat atgcgtaaat taatgtctga 35460 taaattcaaa ggtattgttg aagctaatga taaagaattt aaaacagtcg gtaaacgtat 35520 tgtacagttt gctaaaggta gattgaatgc tagtaagtat cgtgaaaaag tagtatctgt 35580 taatagtaat aatgcaggtt tacagtttag tcctaaattt acagattgtt tatcaaacaa 35640 tcctgaagaa actgaattat ttatagctga gggtgattct gcagtaggat ctattaatga 35700 tggacgtata gctgaaattc aagctgtatt cccgttaaaa ggtaaaccta aacaatctca 35760 ttcaagttca ttaacttcat tattaaagaa tgatgagatt agtgaattaa ttaaaatcat 35820 atttggaact aacgatgtta aaaatataga ttacgataaa gttagatatc ataaaattat 35880 aataacttct gacgctgatg atgacggttg ggtaagattt atttaaaata aaaattagta 35940 taatatattc ttttcaaaga aaggaatatt ttaattatga caaaaagaaa aaccatagag 36000 caatttaaaa aagatttaga tgataaaaaa ggtattggag aatatgatgt tttatccaaa 36060 gaatatataa ataataagac tcatataaaa gtaaaacata aatgtggttt tatttatgaa 36120 gttaaaccaa atcatatatt atataaaaat aattgtcctc aatgttcaat gaatgttaga 36180 gtgtcatcat taaagaaatc aaaaaatata gacccggaaa attatttaag aaaaattact 36240 gaaggttttg aagatgaata tgaatggtta gaagaatata aagggaataa taagtataaa 36300 cataaattat tgcataaaaa atgtaataaa gtgattgatt ttagacctaa tgactttcaa 36360 caaggttata gatgcactaa ttgttattct agttcttcaa gaaaaacacg tttacttaat 36420 agatttttgg atgaaaataa tatacaatac caaagagaag tatcatttaa tggtatatct 36480 ggaaaaagaa ttttaaaatt tgattatcta ataaatgatt ttattattga atatgatggt 36540 atgcaacatt ttaaagttaa taaaaatagt atttttgaag agagttatga acgttgcaaa 36600 gtaaatgatc atataaaaaa tgataaaata aaagaactta attttaattt cattagaata 36660 gattttaaaa ataatatgag cgatataaaa acaattataa aatctatttt agagaatgat 36720 aaagaaatga ttctaagaaa agttatagat aataaattat actactatga taataaaaaa 36780 gaaaaaatat ataatgaaaa aatatattat actaagatga ataaagatta ttttaaataa 36840 attgtaagct gtctttaaac tttattaatt gctgggagtg ccttagagct taattaaatt 36900 ctaattaaga ttggttgatc agcatcggag ctctataatt tatattatgg agatacgttc 36960 aacgactatc gaaaagtgag cattatgtcg agaggaccta ttgcaatata actgagtaga 37020 gtacagccaa gtggtaagca ttgtgctttt aaatggaaac ttagaggcgt gtatttaaca 37080 catatacgta agatatagtc tcaacattta gggaaaccct aaagaagttc ataagagaac 37140 tggtaatgat taacgaccat tgctgaagat tttgttacac attcaagctt tattaatcga 37200 tttattctat acgcatttcc ctgaattaat taaacgtggt tatgtatatg tagctcaacc 37260 acctaaatat tcatataatg aaaaaggtaa attccattat attaaaaatg ataaagagtt 37320 agtggatttt gaatattaaaa tttctagtaa gaaattaaaa ttagaaaatg ctaatttaaa 37380 agatttaatt aacgttaaag ataattatct tgatatattt aataatattt gctctgatat 37440 gagtgtctct gacaaattct tagatagatt tattctattt aatgaagacg aagaagatat 37500 tgatgaagta ttagaatcaa tggaattata tattgacgat aaagataata ttactggtat 37560 ttatgataat atctggcatg atgttaattt agatgattta attaattcta ttggtttact 37620 aattaatgtt cttgaaattg attacctgat cgattttgat tatgacgatg ggaaagaaaa 37680 aggttcatta agtccatata acatgcttaa atttattaat aagaaattta aatttgaata 37740 taattacttt aagggacttg gtgaagttaa tgcaagtgaa ttatttgaaa caactttaga 37800 tccaaagaga agagatttaa taaaagttaa tgaatctaaa tcagacgaag ctattaaaat 37860 gcttgatgat ttattcggta acaaaacaga ttctcgtaga gaattactaa ataaatacta 37920 tcaaactgta tagtatctaa agataatgta actaagatga aaataaacat atattataaa 37980 aatgaggtaa tgacatataa tttgtcatta cctctaatat attaaaataa taggagatga 38040 aatggataat gtcaaataac aaatatattg acgtattgtt aaatgtaatg atgtcaaatg 38100 acccaagtta tggttctgtt gatgtggaag atgcttttat aagagagatg gagaaagatg 38160 atgaagtaat tattaatttg ctagatagaa atagattaaa ctattatgta gctaataaat 38220 tattaagtaa gctatattat aataataaac tatcagatga attaattata aaatatttta 38280 acaaaattgt tgatcttaat aaaaaccatc gtgataaaaa tgaattaatt tatagtttat 38340 ttaaaacgcc aaaaggatta gataaggatt ttaaatttag aaatcgtcta gaattattta 38400 aaatagtcga tagactcatt aaagacgata aaaatgtgga ttctggatat aatcacaagt 38460 attatgactt accaaaaaat aagtataata atgatttaag agttccttta tttaaaaata 38520 aaactattaa aaggacaaga gaagatctag atttaataga aaagcataat cttataaatt 38580 tgctacctat agtctatata tttaattgga aaatgttacc tgataaagtt aatgaagata 38640 taatttctag aataatgaat aatactgaaa aaattagtaa aataagttat ttattaaact 38700 ttttagacaa taaaggtaat agaataataa ataatgataa tcaatcaaat ttattaactt 38760 atttaaatag taaagaagga gtaactcgtt ttgtaaacga attaaaacag attaatggaa 38820 aagataattt caatattaaa atgtataaaa tagttgaaaa tttggatgaa tcattgaata 38880 ttattggtga cacttttaaa gatcctttca aaaaagaaat tgtagcaaat acttttaaat 38940 aattatatta gaggagtgga atttaaaatg aaaaaattat taatggtagt atttattgga 39000 ttgttaacgg tagctttagc aggttgtgga ggaattaaga acgaaataaa aggaacttac 39060 gcatcatcag aaaaagtcat tgtattagag aaagataagt atacattata cgttaaaggt 39120 gaacctgata aacctattga tgtaacttat tacgatgtca ttgatgctga taaccaactt 39180 aataaaatgg tggttgacct taaagatggt aaagatggcg aagttttcac tagagaaaat 39240 tggtataaac aaggaaataa aatggttatg gtaactgaag atggtagctc atttaatgga 39300 tatcctgaag atggtttaaa agactataaa ccatctgacc ctgaagatgt tgagtaggaa 39360 gtgataaata atgactagta tattattata tataatattt tcatttttat tactttatat 39420 aacaacgata actatattta taattggtat aaatagtttt aagaatgata gaaaatttgg 39480 tatttctatt ataacaatgt ctttactaag tataatagct ttaatatact taacatttga 39540 catgtttaga tttttataaa attaaaaaag agagtaggaa atatatatgt ataaagaacc 39600 cagacaagct aaagtagtat atattaatgc agtaactgat gatagaaatg aaattattaa 39660 attagatagc gacacaaaga acgtttattt gaattctaaa atgtatttat cattaaaatt 39720 taatgattta gattttgata caagtagttt aagaatattt gagagagaaa tgacatctag 39780 tgaaactgga aatccaatga gttataaaga atttaaagaa gattattag ttgatggttt 39840 ctatgatccg ctagtagata gtacgataac tattacggac agtaattacg atcataaaat 39900 tgaaattaat gtatataata tttaatttag gatttgtata ttatggaaaa ttataaaaat 39960 aatttaaaag atatattgaa aatggaatat gaagtaagtc tttcagaaat cataaagatt 40020 cttggaagag atagtttacc attaatagaa tctattaaag aaagtaaaga tcttcattta 40080 ttatttaatg caatagatta caacaagatt agtaatgata tgataactga agttgtcaaa 40140 gaaattgtaa aaaataacat ttatgatgat gaaaaattga ttcagctttt aagtaaaatt 40200 tcttccgata gatgtgactt tttagaaaat aattttgaat ttgtaattaa agtaataaat 40260 gatattgata aaaacaaatt taaaatgttt ggaaccaaag ttttgcatgc aatcaatcaa 40320 cttgatttag attcaaagaa tgtagattta attataagaaa attatccgga catttttgat 40380 ttaatgacgg attgtatgac taattatagt tctggattta agataaaaga tgaaaagttt 40440 ctctctgtgg taatgaaaaa atgtgaagaa aacaattcat atacgtatat tgaaatgata 40500 ttaattttaa taaatgcgga tttaaagata ttagaattat taattaaaga aaattttata 40560 caaaacatag tggaatttat aaattctaca aatgatgaga tgctcatcct agtgaaatat 40620 aataaacttg ctaaaataat tctattagtt gataaatatt ataatatcag aaatgatata 40680 gttcaaaatt caaaaagcat tttaactcaa aatactttta aataaattta acatttagtt 40740 taaatatata ttataacaat gaagttatag taatttatta ctataacttc ttcaaaaata 40800 aactatatta ggagatgaca ttatgtcaga ggtaaaagta aatgtagatg taatcaatga 40860 agaaagagga gttactggta ttcgtacacc tcaaaaagtt ttagaactta gagaaggaga 40920 tttaattgac tttgtattct ctccaagtaa tcgagaagaa tttgaagaag atcaaatatg 40980 ttttattgaa caagatgtaa cagatgaatc tttatcaggt aaaattcctt ttagtgattt 41040 tgttaaacaa aaaggtaaat acaaaaaata cgaagttcgt aaagaagtaa tgatttatat 41100 tacttctatt aatgataaag gtccattaga cagcgttaaa attaatattg aaaagtaaaa 41160 taaagggtaa tgatcattaa tctgatcatt accctattta taataatttt tttaatataa 41220 ggagagaaat atataatgtt gacatttatt ggcaaaggtt ctgcttttaa cgaagaaaag 41280 gtaaacaatt cagcttattt tacagatgat aaaaataaaa atttatttat tattgattgt 41340 ggtaatacag tattcaatca gattaaaaga attaatttaa ttgaagagca tatagactac 41400 aagatttata ttttagtgac tcatgtacat gcagaccatg ttggttcatt aggaacttta 41460 attgaatatg tatattataa ttataacaag aaattaaata ttatatctat ggccgataca 41520 ggaattggag aatatttaag tagtttaaaa ttaagtaatg atctttataa ttatagacct 41580 gcagttgtaa ataataacgg atattttagt ttacctagtg atttccataa atttgaattc 41640 gatgatattg aaatattctt tattaagaca aaacatgtta ttaatcttaa tacttactca 41700 ttaattgataa ctaagtatat gcttaaagaa aaaagatttg acagtattta ttatacttca 41760 gatacaatag aaacaccaga tcaacattta agaagactag aacaaaaagt taaaaatgaa 41820 attaatagaa gtattagtta ctattatacc gatgtatctt tcaaagaaga aaacaatgtt 41880 catttaactt atgatcgatt attaagtggt attaaaatta gccctatgga gtggttaaaa 41940 gattatcata aggattttgg cactaaatta aaattaatgc atattgatga taatagtatt 42000 gatataaatg ataaagaaga agaattaaat gagatattaa aaggagagta aaaaagatga 42060 ctaaagaaat ggatgaaata attaaaaatt tagagagtaa atatgttgat cctgatttag 42120 agaacgatgt ctactcagaa aggtattttt ctatagctat ggttgatggt ataaaaaata 42180 tatttgatat tattttaaaa gaaataaaag acaaagataa tgtatcagat attgaaagat 42240 tagatactga gagacttcaa cctagaaatt taatgtctaa agaaaatcct atgatgaaaa 42300 atttctttga tatagcttat gaagttataa tggaaaataa atctatgata agtgaagccg 42360 attctttatc ttcatctttt gttaatttta ctaacagaaa tagagtagtt ataaagatga 42420 ataaaactta tttaggtttc aggtatattg aaataatgag aaataatagt gggaattttt 42480 atatcaatct agccaattac gataaaactt ttaagcctaa cagtggttat tacgatgatc 42540 aactttgtat tacttttaga aataagacgt ttagatttca ttatctcaca tataattata 42600 attcataatt aacttctact tataataaaa tataagaaag aagtgtaaga gctttgtcac 42660 aagaaaaatt aaataatgaa gaagaatggt atgacgttaa aggatataaa ggaatactta 42720 aaataactaa atctggtaga gtaaagcgtg tagcagatat agttaaagat catagaggaa 42780 gaatgcacat agttaaagaa tgtgaatatg cattatttaa aaatagtaat ggtgctaagt 42840 actttactat gaattacaaa ggtaaaaaat atactataca agtacacatt ttattggcta 42900 aaacgtttgt aaaaaatcca aaaccatatg aatatgattc agtacatttc attgatggga 42960 ataaagaaaa tattagtata gaaaatttat gctgggttcc taaatcatat tttacttttt 43020 atcatagaca tagatatgat aaaggtctat ttgaaaagct aggaaaagaa atgaaatata 43080 tttaatgaaa gtgtatgatt tgcatatatt ggaattgtct taataataaa tactataaaa 43140 acaatattat ataatatatt ttaaaaaagg acgttatata atgggcgata ttagtaaaga 43200 caatttatat atttttagag caaaatgtga aagagtagtt gatggtgaca ctatcgatgt 43260 cattattgat ttcggttttg atgtgagtgc aaaaagaaga gtaagaattc ttgatgtaga 43320 tactccagaa agaggacaag ataattttaa agaagcaact gaatttgtta aagaacgtgt 43380 ggaaggtaaa gagttactat tacaaactta caaatctgat gtttttggaa gataccttgc 43440 tagaatttgg tataataatg aagatactgg taaagtatgt ttaaatgatg aattattaat 43500 gtctgatctg ttaaaaccaa attcaaaatg gaataatatg aacaatattt aaaaattacc 43560 taatacctaa atactggtat taggtttctt atttaagcct ttaaaaataa aatacattta 43620 aggaagttgg tatattttga ataagttaaa tttagacaat attgaagatt tatcattaat 43680 ggttaaaaaa ctaagacctg aaattgaaga atcgacaaat gaatttagaa tgatatctga 43740 attagaaaaa atatttatac aatacaatct taaaaataga attcttgaaa agtcttctga 43800 atttaatata tttgaattta atgaaatttt aaatggtcag cataataaag acgatgtgtt 43860 tagtttcttt gttaatttca aagatttttt agattatgaa gaagatatag atatctatgg 43920 tttaatagaa ataaatgtat ttgataatcg ttctcttaag gaagaaatgg atattcaaga 43980 attagacgat tttatggtac aaggaaaagc ttatatcata tcagaatctt ttaattttat 44040 tgataagaaa gttcctatgt attttggaga tttttatata ggggaatatg gtatgatgca 44100 aaatctagat ttcatgaagg acatatactc tgaagtaatg atgactataa atgacgaagg 44160 tttattataa acatcaaatt attcacacat atagatggag agatgttcac tatgaaaata 44220 ttttacaatt cttatattct catggataca ggtccttcaa tagattctta taattatgat 44280 ggaacatata ttagtcaaag tgaagattta acaacagcta gtttcgtatc tagtgatgaa 44340 ttcctcggat ttcttttaat ttcactcata tctatatttt tagtatcgtt tgtcatattt 44400 agaactataa agaacaatag aaagagaaag aaaaataaga aaagataaat attaaattaa 44460 cctaatactc taaataatga gtattaggtt aatattttta gaaatttgca ataacgagaa 44520 tttataatat ttaaaagtaa aggatgaaat agataatggc agaagttttt aataaagatt 44580 taaaagaaat agttcacgat aatatgatga tatattttaa tgaaattaac actaaccgtc 44640 aaataccaga tattagagat ggtttgaaac ctattcaaag aaaaatactt tatattatgt 44700 ataaaaatgg ttatagatct gataagaaat ttgctaaatc agctagaata gctggtgaca 44760 ctactatatt acacccacat agtaatgatg gtatttatga ttctgcagtt aatatggtta 44820 caccgttttc tatgaaccaa ccattaattg aaggacatgg tgcatttggt tctattacag 44880 gagcttcagc agccgcttca cgttattgtt taactggaga acatatagtt gatatgagta 44940 atggagaact tgtaagaatt aaagatatag tacctcatag tgaattagac agtgataata 45000 aaattgataa agttgtcatg gactttagac gtaaaccagt taaagcaatt aaattcttta 45060 attcaggtaa acataatgta atggaattaa acactaatgc aggtaaaact attaaagcta 45120 ctccaaatca tcctttatta accgtaatca aacatccaac aaaaggatta gatttcaaat 45180 ggaaaacaat ggatgaaatt gaaaaagggg attacttaat caacagaact atgattaaga 45240 atgatctcaa agattttaga agtaaaaatc ttaatgaaaa tgagaaagaa agctttaaaa 45300 aatggggaga aattctttct aataaatact ttaatagaac tttagatcct gaatatggag 45360 tattaatgag aagtattgaa actgaaaaga gccttcctaa taaagtgtta gaagcttgtt 45420 taggttataa aagagaattc ttattagagt tatttaaaca agatggattt attgtagata 45480 atattggttt agttatcgaa agtcatagta aaagattctt gcaagaaata gctactttat 45540 tatctcaatt tggtatttat tctgtgatat cattattcag tgatagtgat tatagattac 45600 aaattcaaga tattcactca cttaagaatt tatctaaaca cttaattaaa gatgatgatt 45660 tattaaaaga taaaattgat gaaattattg atatgtatag aaatttagaa agtaataatc 45720 catatcaagt tattccttat tagatgaag tattagatga gagaaaaatg acttcttatc 45780 tatatccaga gttatttaat actagaaaga atttcttaaa taactttaat ttacttgaag 45840 aagaatacgg tattgaaatt gaagaaagag atcatttaat gttatttatc tctaaatact 45900 tagataacta tacttatttt gaacaagtag aaagtattga agagttggaa gaagaggaag 45960 tagtttattc tattaaagtt gatacagatg atcattcatt tatgtctgaa ggatttattc 46020 atcataatac agaaatgaga ttaaataaat tctcagaaag aaatttatta gataatatca 46080 atgataatgc agttaatatg gttaagaact ttgatggatc aatgttagaa cctttagtgt 46140 taccttctaa attaccttat gtattagtta atggttcatt tggtattggt ggtggaggac 46200 atagatctga tttgccacca cattctactg aagatgtaat taatattact attgacagaa 46260 ttaaaaatcc taataagaaa ttaaaaacac ttattaaaga taataaattt aaaccacaat 46320 ttccttatgg tggagaagca ttttgtgatg atttagagaa atgttatcgt acaggtaaag 46380 gttctatgtt attaagatct gtagttgaaa aagatgaaag taaaatgact cttacaatta 46440 aagaaattcc ttataacgtt actttgacta gggttaaaga agctatcaga gaagcacata 46500 aagaggaaca attagatggt cttaaaaata ttagtgacgg aactcaaaac ggagatgttc 46560 gtttaattct tcaatataca aaatcttctg acttagattt agcattaaat caattgtata 46620 aagttaagac aattacttct agagttaact ttgatgttaa attagtagat aataataagc 46680 tagtggaaac taatttatta ggtattattg atagatggat tgaatttaga caatcaactg 46740 tgaaacgttt taaatcattt aaaattaaag atttaagaag tcgtattcat attattgaag 46800 gtctattagt tgtattagat tctaagaata tcgatgaatt aattaaaata gttaaatctg 46860 gtaaaggtaa agaagatatt attgatgtag ttagtaagaa atttggtata tctcatgcac 46920 aagcttctta tgtagctgaa atgaaactat atacaattaa taatcttgaa atcaacaaat 46980 tggttgaaga aaagaaagaa aaagaaaaga ttgttaatga agaaatggta tacatgaaag 47040 atgtaagtaa actgaatgat cttattatta atgaaatgaa agaaattaag aaagataaaa 47100 atacacttaa accatctaga ttaactaagt actctgatat tgattttaaa aatgataata 47160 aagaattatt aattaaagat gaagattca tgtgtattat tactagacaa aataagatta 47220 agaaagttaa agatgaaatt agtaaacctc aaaagagaaa tggtaaaggt atctctattg 47280 gtaaattatc agatggtgat attccattaa acatctttaa tgctaatagt aaagataact 47340 tattcttaat tactgataca ggaaaaatat tctatgataa agtttatgaa ttccctgaaa 47400 ttaaatcatt gaataacttt ggtaaagata ttagtagatt tgttaagaat gaaaagatta 47460 ttaaagcatt tactttaact gatgaagaat ttaaagatcc agatacagct tttgtagtaa 47520 caacagcttt gaataaaact aaaatggtta tggttgaaga aattaaaaaa tctggtgtaa 47580 ttcttatgaa attaaatgaa gatgataaag ttatcaatgt tcataatgta cattctaaga 47640 aaccatttaa tttaatagct atatctgaaa aaggtaatgc tattagattc tcaagtgaat 47700 taattccagt tcaaaataga aatacaattg gttcttctat attcagtaat acaactatta 47760 ataaagataa taaagttgct tcaactgtag ttgattctgg acaagataaa atgttaatag 47820 ttactcataa aggtttagct aaacaaatta tgactgaaga cattccagtt aaatctagaa 47880 tgattaaagg tgtaattgca gctaaattta aaaatgaaaa agattctgta atgtatatta 47940 gtatgataga tgatgaagaa gataatctat tattagttac tgaaaacaaa actattaatg 48000 tacctttaaa agaaatcaat acgtataaaa gaacaactta tggcaatcca gtaatgaaac 48060 ttaatgataa cgaattctgt atagattctt ctatcattaa acataattag ttgagaaaga 48120 agtgtattat atgaaaccat gtaaatatat tataaaaata agtaatgatt cttatctttg 48180 ctataagtat gatgaacctt tagaaacaac agataaaaag aaagcaacta gattaatga 48240 gcttgaatta gcacaagaag aagtgaaatt aatgggaatt ggtgaaattg aaaaaattcc 48300 ttataaataa aaattaatca gggagatgac attaatttgt catctccctc atattattaa 48360 ttttttggta aattctcttg aaacaaccaa atattgttaa ataaaaagaa ttggatgtga 48420 aatatattgg aaaagaaata tattagatgt aattcatgta gttcagtaca agaatatagt 48480 gaagatatta catcttgttc agaatgtagt tctgagaata tttcagtcat taaatctcct 48540 attgatttag ttaatgaagc tgaagtatta gttacagaat ctgaaatgga tttcctatta 48600 gattataatg atagtcaaga gtatgataaa aatggtaaat cttgttggtt tgatatatat 48660 ttaattaaat accctagaga taacactcaa attaaatata ttgtattaca aaatcaaaaa 48720 ggtagagaag aggatatatt aatcgatttt gccggagata ttaaaggcgg aaatcctatt 48780 gtaataaatg atacaggaag tattaagact gtattaaatg atgttgatgg attatctgaa 48840 gttgttaaag ttagattctt aagtaaagaa tcaactaaga gaaaaggtaa agaagatttt 48900 ggtttaaatt cagaagaata cattagttat aataaagata aaaataattt ctataatgat 48960 gctaaattga gaactttaat taaagtttta gaatctatga ataatactct attctttgac 49020 agtaaagatg atatcattta caataaaata tttactgaaa ataatgtact taattcacct 49080 ttatttaacta ataagactgt aatgagttat aatgaaactg aagtatataa gaattatgga 49140 gattataaat ttgatgaaag attagatagc gttatatatg attatcaaat agaaaatgaa 49200 ataggtgcgt ttactttctt atataataaa aataaagaaa ataaacctaa attcactgaa 49260 gataagagta gtgaaattta tgctacaata actccatcta tgttcttatc tgatgaattt 49320 agaatgttag acgattatgg tagagttaat ccaaacgtat tagcattatt atactttaaa 49380 atattagaga aaaaattag tatcagatct attgaattag taacttatgt aaatcctaat 49440 aaagatgata taatgttatt ccctgtttct tataatggac aaggttacgt attagctgat 49500 ttccatttag atagccctat agtatttaag aatatggatg atgttaataa gtattgtgca 49560 tatcaatttg gatatgacca agaaaatgaa gatgataaag gaacatttaa attctcagta 49620 aaagaagttc ctgctgaatt cgatttccaa aaagctattt caagtaatat ggaaattatt 49680 gaaagattct tcatgaaatt caatgagaat actttaaatg aaactgtatt agaaccagaa 49740 tcaatcttaa atgaagctgt tggagataat aaaaagaaac gtcaagaaat acaaaataaa 49800 atattagacg ttatttcttc attagacaaa gatcaatcta atatgaataa atataaaaca 49860 ttctttgatg aaatgaatga tgaagaattc atgagatata ttaagagatt tgttaatagt 49920 aatgaaaact tctacattga agtattacct aataaatctg aagctggatt taaagaagtt 49980 gaagaagctt taaacaaact tgatgtacct atgaatgaat ttgtttatta tcgacatgat 50040 ggaaataaag atgatccttt aagaactaga tataaagttc cagtagggta tttacatgta 50100 aaacgtctac gtgtgaaacg ttacacaaga aagacaatga agattgttga ggattgtgtg 50160 gcataattta ttatgccaac tttttagttg aataagcagt atctacctat aaagatacga 50220 tatgctatta ataatactcc cgcatgtata agaagtgatt tttatatgtg aagccgggtg 50280 aagtcactat attttaatta tagtggttag ggaaatgtat atggttagga acacgaacta 50340 tttatgaatg tcctttatat attagtatta aatgtaggct taatactatg atttaattaa 50400 taggttatta aatctcttaa cggaatataa agggaacaga tagaacctaa gtacatttat 50460 ttacctagac taaaaggaac gtttgatatc tcataatttt ttatgagaag taagagagaa 50520 tatagtaccg ttgaagctat gataataagt agtgaaggga aagttcttag tcataaaaat 50580 cataaactct cccatatttt tatgatggaa agccgtatga ggtgaaagtc tcacgtacgg 50640 tttggtgcag gggaaaagag gtacgcttag tatactctta cctattgcaa taacagttac 50700 tttcgaaaaa gaatgcatac agtttagatg cttcaactag atcaatgaag acaggtcaat 50760 tgacaagttc tgataaagta gcaagtgtat caaatatgga agcttctgca ttgaaagcta 50820 ttggagctca agatatctta agagaattga tgggtccacg ttcagactct atgaatgcta 50880 agcaagaatt aaataaaaac atctctatgt atggatattc tcgtttagag gatttaccag 50940 atgatctttc tgataagact acattaaata ctactttcta ttatttactt ggtgctggta 51000 tagaatctga tttaacttaaa gacactagac ctgattatga tcaagaagaa taataaatat 51060 atattataaa aatgaggtaa tgacattagc ttgtcattac ctctaatata tttaaataat 51120 aggagagtgt tttggatatg gaaaaagtta tagaaaatac ggtaaaagaa ttaagagaat 51180 tggcagtaaa agaaatagag ttttttggtg aacctgaaat aaacgtattt catattaatg 51240 gatatacact tataagctta agtagagatt tttatctttt cacatcagtt aaagatgata 51300 ataaagagat tttaaacgca ttattaaaag atgatttatt taattatttt gatgaatatg 51360 ataataaatt tggatttttc gtatattatg aaactgttgt agataaaaag acaaataaaa 51420 aaggagaatg gaagaatctc aaacaattaa tagatacttt tgaatgggaa aatggagacc 51480 ttttagaatt tgtaaaggaa gaaaatttat cagtgaatga gtcgttaaag aaaaaagaat 51540 taagagaatc tacagaagaa ttataaaatt gagtagaaca tataagtatc cttaagttca 51600 tacaatttat atgaatttag aaaggagtaa ctatatgatt acttggttaa tagctatact 51660 agtagtttta ttaatactag gtattatatt ccgtggaccc ctagcagtaa taccacctat 51720 gggatggtct ggaattgtag ttgcaatctt agttatatta gtagtatttt acctattcag 51780 gtagataaag aggtaatggc atattatatg tcattacctc taatatatcg caattaaagt 51840 attttcaagt atatattatt taaatgagat aatgattata ccaatcatta tcttttaata 51900 aaaaacagga ggtataaggt atgaaagaat taacaagttc agtagaaaag gcagcaggta 51960 caagttgggt gcgttagtaa cacatcaagt ttttataggg ttaggtttag ttttattaag 52020 tttaatcgta tttgctattt tgtattatgc atttaaaaaa ttaaatgtca tgaataactt 52080 atcacctatc attgtattgg tagttatttt agttattgga attgatttgg ctttattcgg 52140 atacggttta atgcatatat ttaatccagg atattatgca ttacaagaaa ttaaagaagt 52200 cattaaataa atgatttcaa tgaatcaata caataataga taataattaa aaaaagttat 52260 tatctattat tatttttaaa ctaggagagt gaaattgata tgaataaaga ttatgaaaaa 52320 gtaaagctaa attctataaa tgaaatattg ggaggagtgg atattgaatc ttctttatat 52380 agattttggg aaatatacag caagaaatat gatgaatatg tctatttggt ttttgaagac 52440 atagagtatg agaataatta taacaataca gttaatatca aagggatatt tagaattgac 52500 acttctgata aatctttatt atttgaagat gaatttacat tcaataatgt attggtaaca 52560 gattcagctg aggattttgg tattagagta gataactatg catatgatga tctaataaaa 52620 catctagagg aaaataaaat tatttaaaat tataggagat gaatagatat gagaaaagaa 52680 ttaagtgatt atattaataa ggaaaaattg gatgcattaa gtatatcttt acaaggagat 52740 gattttgatt ctttagaacc aaaagctaaa gaagaagtat ttgaaaaata cttaaaatta 52800 gaaaaattgc atgtagaatt tagatatgaa gaatcattga gtaaaattgc agaatctttg 52860 aaggatgctt cacgtaaaga aaccaattca gattcaagta atgtagataa agaagctatt 52920 ttatcagctt taaagaattt tgcacgtaaa atttaaatag agagtaggta aaacattgga 52980 tgaagtaaga caaatagaaa aatatgtaga tgtagaaaaa ttaaatgcta taagtaatta 53040 cctctttaga tgtgattttg atagtaatag ttctatggta ggtcaatcag gaagaaaaga 53100 aattttagaa gtttatatgg taatggatag aaatgatatt caacattatt tagctaagaa 53160 aattgaagaa aatggagata aactttgtaa ttctctaagt gaatttgaag aattaataaa 53220 aaggataaag gggatgtaaa ttaaaatgaa aaaattaatg attttaggtc taacaatatt 53280 tttaacagtt attttagcag catgtagcgg tgaagaaaag aaccctagtg aagaaaaagc 53340 aaaaggagat agttataaat taatatatta tgaaatttta aataatggag atagtgatta 53400 tcctagagta gaaattgctt atgaaaatag aattaaagaa gttcaatctg aatctattga 53460 tatcgataat ttaattgagc atgtctcaaa agacccaaaa gaaaaaccta aattagttat 53520 tgacggtgat gattatcatg tatatagaca accttatatg acttataatc aagaagacat 53580 tgaaggtaaa gtagaaagta aagaggaagt ggaaaaataa tgaaaaagtt ttctatgatc 53640 ctagtatcaa taattacatt attagcattt gttagtcaag atgtattagc tattggaagt 53700 tcaacttcca gtagttcttc atcttcttca tcagtcagct catctgcatc gagatcatca 53760 acttcatcaa gtatgagttc ttcatcagca agtagatcag ctatgcaaag tagtatgaat 53820 gctcgaaata gtactaacag tgcaagtaga aatagttcat tgaacagtag tatgagtaga 53880 aataattcat cattttcatt aactaaccca aatagtatgt ataatagaaa taatcaaatg 53940 aattcatata attcacagct tagacaaagt aattatatga ataatatgtt gatgtactat 54000 ttattattta atggtattaa taatcaaaat aacttaaaga aacagaaatc aattttaatg 54060 aatcaaatga ataaagatca aaagttatat acagtgacaa ttaaaactaa aaataataaa 54120 aagcaattgt taactgttac taaaaaggat tatgataaaa ttaaagaagg agatactgtt 54180 aaatattcta ataataaatt agaaataaaa taataaaagg gtgatcaaat tatgaaatta 54240 ataaaaacac tattaattgt aacattatca ttctttttac tgaccgggtt tagtaaagat 54300 gaaagaatta gtggagattt aattgataaa gtaactgaaa tagaatcagg tgatgagatt 54360 aattatttga ttctaaaaga tgaagataag ggaaagacaa aaatagatgt tgacaaagaa 54420 gtatttgata aactatcaaa aaatgatgac atagttatta atgaagatgg taaagtctat 54480 tcaaatggaa aatttattga ttattatgat ggagatcaaa cgccatatta tgtacttggt 54540 ataattatgg gttcaataat tatattagga tttatatcag taatcattat agatttattc 54600 ccttattcaa tataaagtta agagataaaa taatatttaa ctaggagatg aattagatat 54660 gacagaaaaa attctaaatt taaaaatagt agtgagcaat gatttaaaag atgtatatga 54720 tacaaaatta tctggaggag gttataaaaa taatgaaata atggtatcag aaaatgatat 54780 tttaaaaata aaattagata ttaaagatga acaaggtaaa gaattaaaat tagaagacat 54840 aaatcactta ataagagttg gatctaatgt taaaaatatt aaaagacttt ttgatagatt 54900 ttataaaata gatgaatttt ttgaaaaaga tggggaatac tatttatata aaataaaaga 54960 aaatatggac actcaatgtt taatgtttag cgtatacaat ttagattcag aaattgatga 55020 agacgtttta attgacatct ttatttataa tgatagtttt cataaatcag tattaggagt 55080 agttaataga tatattgaaa ataaaaaaga tgaagatata gttaaaaatt ttgtatctga 55140 tattagaagt gattttgatg aaaaagaaat tgaatataca atagaaaata ttgacgattt 55200 actttttagt agcaatgttt ttgatttatt aaattacgta catgaaaata gtcatactga 55260 tgaggttatt gattgttttt cagaggaaat tcaaaaatct ttaagtgaat cagtaagtgc 55320 tgaaagtcgt aatgaaaatt atacttttgc tgaaggtata aataatattt ttggaattgc 55380 aggattttct ctaacaaatg gcagtgtttt taaatttaat tacttatatg tataatatta 55440 atattaggag atgaattaga tatggaaaat aacaaaaatg aattaattag cagagagaat 55500 atttcaccag aggtttttaa aaaggttgat gaaattaata tacttgataa gaaatctatt 55560 attgagtatg gacatgaagt acaagataag ttatctaaag aatcagataa agtattaaag 55620 aatattaaag aaaatgattc taatgaaaag attaataaag tattagatga tatgttagat 55680 gtatttaact catatgatcc acaaaagatt gatgagaata tgaaacaaga agaaaaaggt 55740 ttcatggata aaattaaatc tatgtttaat aaaggtaaag aaaacttaat tggtaaagaa 55800 ttatctaaag ttgattcagc ttcaaataat atgactttca ttgaaagaca attaaaagaa 55860 agtagttctt cagttgatac tgcaaataaa aatttagata atttaattca atctaataaa 55920 gattattatg agaacttaag tgaatatatt gaagcagcta aatataagaa attagagtta 55980 acagatgaaa ttcaaaaaga tactgatgaa gttaaaaata ttgaagatac tggtgaaaaa 56040 caaaatcaaa ttcaattagt atctgataaa gaacaaggtt tagataatct tgataaacgt 56100 atttatgact taagtacat attagcttta gcagaacaaa atgtatttga attagaaatg 56160 attaagaata tcaattatatag tcttaaagaa aatattaata actctttagt aaatagtatc 56220 cctatctgga aatctcaatt aactaaagca gtagtattga ttcaacaaca acaatcaatt 56280 aaaactaata aagctattag agaagcaact tctgatattt tattaagtaa ctctaatatt 56340 cttaaagata acgcagttca gatgtataat gaatctaata aatcatttat tgatattgat 56400 gttcttaaac aaactcaaag taatatgatt gaaatgacag aagatttaaa acgtatgtct 56460 gaagaagctt ataatgaaag attgcgtggt tatgaagaac ttaaagaaat taaggaagat 56520 aaaaaagaat tagaaaataa gaaaatagaa atgtaagaag gtgtattatc acatgttaga 56580 tattttaatc tattcatttt ctggtttcgc cattgtagga ggttctgcaa tggcgattta 56640 taatggaaat aagttagtta aaaagaaaaa aagagtctca caaaatgaat taaaacttaa 56700 agatacagaa gaattaattg atctcaatga aactaaaata atggaaaaat taaatgattc 56760 ttataaatta gaaaatgctt ttgactgtaa ggaaagatac tacgctttac attatctatt 56820 gagtcatcca gaaatggaat tctataaaga aatagccact catatttatt cagctgtttt 56880 aaatgaaaaa actaatattg gagctgaata tactaaagat ttatttattg aagggaaatc 56940 ctatgataaa agattagact tattgacatt ctctttagta tacaaaaaag atagtaaatt 57000 tgaaattaac aaagaaaatg gaattatgga agagtttaaa gatttacttg acactaatat 57060 agaagattta gagatgctag aaagagaagg ttttatatat acgaaagatg actcaggcat 57120 attttataaa tatttatttt tcgggactaa aatactaatc ggtttagtta atttacatgg 57180 tgattattat ataactatta tagatgaaaa agaaaacgtt tatattaaag atatgaaact 57240 tggtgaagag ttggatgctt tacaatattt tgacggaaga aggtttttgt atcatccatt 57300 agatttcttt atattagaag atggcgaatt acaaatatta gatccaaatt catataattt 57360 agaacatgtt aacaataaaa aaataatatt tgatcctaag tcttatgatt cagaacctat 57420 agggaataag cgtataaact tatatcatga agacatagaa tttaaaaaag ttccttttaa 57480 cactgaagga ttattaaatt atttaaataa tgatgttaaa atagaaaatg atgattttat 57540 ttatcttaaa ggaaacaaag tggaaagaaa tatagataag aatcattggt cgaatttaat 57600 agaaactaat tatatgatga attatagaga taaaaagaaa ttcatgaaaa atattcataa 57660 taaattagtg gaagagaaaa gaatgaaaga tattgaagaa tataaaagtt actctgaaat 57720 agggagaaag gagtgaagat tctttgagta aagatttttt ctctcataat aatgtaaatt 57780 ataaaaaaga tttagataaa caacttgatg aagatttaga taaactttat ggacaacagt 57840 ctatggatat taatccatac ggtcataaag gctttgttaa caaagatgtt agagaagcta 57900 aagaaaaact tgataaactt aatgatgatt tgatgcgtaa aggacacagt gcaatgattg 57960 atactgattt aattctaaag gaaattgata aacgcaaaac tttagaaagg gaaaaattga 58020 atggcgttta tgacagtata tataattttg gttctataaa tcctgtaagt catagtcact 58080 atagacagct ggatgagatt aataaacgta atactaatat aaaaaataac tctcgtaatt 58140 atattaaaaa agatttagat gaagaagcat tgaatagaag acaatataga aatatgtgga 58200 ataaacctgt aatgacttat gaacaaaaat taatgaatag attagatgaa ataagaagta 58260 agaaaataac taataaaaat aaagaaagat atactgttga agtttcagca ataatgtata 58320 taacaagttg taaatttatt cctgaattta ctaaagatga tataattaat acttattttg 58380 atgtaaaaga aatgatgaac aaaaaagata aaatcttagg aaatggtgaa agtgtaaaaa 58440 atttcacttt aatatttgct aaagctatat ggtttttaag aggaaatatt aaagaaaaga 58500 gtataataac aaatcattca gcacatgcaa ttaataataa ttttttaata aaagatttat 58560 atgatcttag agtattttaa ttaggagagt gaaaaagata tgggaagttt aataggttta 58620 attgtgctaa tagtaaattc actattagca tcaattttta tttttagtaa cttaggaaaa 58680 atgggtaaat ttaaaaacag ttcatgggtt ccaattgaaa gagagataaa aaatagaatg 58740 aaattcttaa tgactattaa ttttattcta tttctatcat cattaatatt attatttaaa 58800 aatattatat cggctcaagt atcattatta tcaataatta tatttggagg agtatttata 58860 ttctttttat ttaaattgat gagagacaat cagtatttta gtaagagtaa taaattttat 58920 aatacagttt atatgatgag tctattttta ttaacaatag atgttttatt atcattttat 58980 aatctataaa agattaaaga aatatataag ttaaataaag atgaggtaat ggcaaattat 59040 atgtcattac ctccaatata ctataaggag agtttaaaat gaaaaaatca ttaataacag 59100 catcattatt aagtacggta atactgttgg gagcatgtgg aaacgaagga tcatcatcat 59160 cagagaataa agggtcaaac ttaaaaccag aaaagcaaga agaaatttat tctaaagaag 59220 caaaattatt aggtaaagca ataagtaatg aagatgctat ggatgattct acaaataaag 59280 tttcagatga ttttaagaaa tctttagaca gatatgaaga taaaactaaa aatttagata 59340 gcgtagatac tcaagttggt gattaactt taagagttgg aaaatctatt gaaatcatga 59400 gtgaacgcat gtatgaatta gataagttca ataaagataa tccagataaa gaaatggaat 59460 acaatctagc tcttgttgat gttggaatta ataccgctca atctctagaa agtataaatg 59520 aagattatga atcaatcgat gtatcatata aaaatgaaac tatcggtaag aaagctaatg 59580 aagaagtaac tgatgtttta tcaactttcc cagcatatga acttgatgaa ttgatagatg 59640 attatggaac tggcattgtt ggaaatgatg aaacagatct aacacaagaa caacaaaaag 59700 tattatcaga cactaaatat cgagatgaac ttaaaaaaga agtaatgact caagaagaac 59760 cagacacttc taaaaatgaa tataatgaat ctgtgaatat gtttaataaa tttgcaccag 59820 aattccttca ttataaagaa gtagatgaaa tggtatcttc aacagaaaat aacaatatga 59880 tggatatcag aaatgctgtt gtaagtgcta atacagatgc tggagtagat agttatgaag 59940 atatggaaga agatgctgaa tcattagaag atgatactga gagtatcgaa gatgaagaaa 60000 gctcagatga cgaaggatat gatattgatg gctggtctgc agaatcttat aatgaattag 60060 tagatgaata taacgctctt accgatggtg aaaaaatgga tcacgtagat gaagatgtat 60120 ctaatattga atatgaacaa ttagaagaaa gagtcgcaaa attagaagaa taacggagga 60180 aattaaatga agagaatctt taaaagttta actctttata tctttttatt tgttttagct 60240 tctttaacct tatttttagg gtttaaagaa gctattaatt atatcatatt gggattatta 60300 actttcttat taatcctttc tttttacttc ttattaagtt atgcatataa tttaattata 60360 tcattatttg gatataagaa attaaaaaga gattatgata ttatagcacc taaaactaga 60420 tttttaataa tggtagctgc tcataatgaa gagaccgtta ttagagaaac tattaaaaat 60480 cttaaaaaga ttaattatga caaaagcatg tttgatatct gtatagtttc agataattct 60540 acagataata caacaaatat tgctttagaa gaaaatgtta ttgttgtaga tacgattaaa 60600 ggaagatttg aaagagaagg cgttggaaaa ccagcaggat tacaatatgc attaagggaa 60660 ttaggatttg aaagtataaa agataaatat gatttagtaa tggtattaga cgcagataat 60720 tttgttagtc ctaatatatt aagagaagta aattctcaat atatcgctaa aaataaacct 60780 gaagcgattc aagtttattt agatagtaaa aattatgaca gtatgatgtc tttagcatat 60840 agtgcagtat tttggactaa taataaattt attcaagctg ctaaatatag attaggttta 60900 ccgaattcaa tcggaggaac aggtttctca gttagatcag attatcttat tgatagtgga 60960 ggatttaact atgaatcatt aacagaagat ttagaaatgg aagttgaaat agttagtaat 61020 ggtggaagag ttttatggaa tgactttgca tctatttatg atgaaaaacc agaaggattg 61080 aaagtttcta tggtccaacg tttgagatgg gctaagggtc atttttatgt aggatataaa 61140 aatttctttc cattattaaa attattcgca aagacattta atattaaata tatagataaa 61200 atagttttcc ttatgacaat gggaagaagt ttacatttag cattaatgtt gttagttata 61260 tcattacaag gattatattt atatttaaat aataaaacag aaatcatcat aaataatttt 61320 cattatccaa ctgtattaca attattaaat gataatttct tattcttagg aacttttaat 61380 gctattctat taagttacag tttcttattt ttaccattat attctatata taataaaata 61440 aagagtaaaa atataattaa gaatgcaata tcatttttat attatgtggt aactgatttt 61500 atagttcaaa ctcaagctat atttgtttgg aaagaacaaa agaattgggt aagaactcct 61560 catgataaaa ataaaataaa aacagacaaa taatattgaa tgtggataaa taaataataa 61620 aggagaaatt gaatgttttc aataactata atattaatga tagcactact aatagtgcta 61680 tcatgttata cccataaatt aaataaagag aataaagatg tagatttaac cgaaaatatg 61740 cctagatatg ctatggcaaa cagaaatgct aaattaatct atattaaagc agattctaaa 61800 agttatttaa actatcagat taacgaattc aaaaataata aaagatcaa agattatggt 61860 tacgaaattg ataaggttga ttgggatgga aatattgttc atgagagtag agatagtgac 61920 ctcaaattga ttaaagatcg gagaagatga ttatgggatt aatagtcatt acattagcat 61980 ttactacact tattcttatt gtaattattc tcttacaagc aaatcaaata aaaaatatta 62040 ataaaaataa tgatagatat tttaacgaag acgaatttca taatagtcaa gatatttttg 62100 gttataatga aaaaggaatt atgggttttt taaatatgtc tttttcatta gtttcagaat 62160 atgataaaaa agaaagattg tatgcaggac attacttatt aaaaaatatg aatgcaaaat 62220 ttttgatatt tgattctaac catgaaacat ataaagaagt aacttcaaaa gaactactac 62280 ttgaaaaaga taaaagagaa tatctttttt caagacaaat agaaagacct aaattttatg 62340 atcattggtc taatttaatt caaactaata aaaaactcaa cattaagaac ttgaaaaaat 62400 taacgaataa atacgacaat attctaaaac aaaaatttga cttagaacag attaatgaat 62460 ttaaagatta tatggaagga agaattactt tatgacagta ttaataatat tatccataat 62520 gactttttta gttgtagcat ttggcattat tgagaaagat gttgatatcc ttgcaactgg 62580 agctttaatt gcatgtttgg cattgtttta cgtagctttt gggataatct aaaaagaaaa 62640 taaaaagatc ggagaaataa ttatgattat agcacctatt ttattgataa tatctgtttt 62700 tttaataata gcttcattga tatcttttgt tataacagtt ataaatttta atgaaggaat 62760 agtttcttta ataattgcag ttgcaggatt tatagttttc ttattatctt gtgtatttgg 62820 aatgataggt ttataaaatt aaagatcgga gaaaataatt atgggtacat ttttgggaat 62880 atcactctta gtgtcttttg gattaacttt aatcttcttt ttattaacag ctgtatttga 62940 tgattttgac atattattaa tgataactgt tatttctgct ataataactg tagtactatt 63000 tatatcctta ggtatatttg ctatacttaa cgaaagtcaa ttctattatt aagaataaat 63060 attaagagag gatggttaga tgtgaattta tttaatttat ttaaaaaaga agataaaaga 63120 ttagcattaa taagaaataa atttgatgaa gaaaaaatta ctgcagtaat cagaaaagaa 63180 ggtaataaaa ttgaagtgga atatttatta tttaatgatg aaaattgcat gatgagacct 63240 tcttattatt ctgaagaaga tcgtttagaa gtagaaaaca aaataaaagc tgttatggca 63300 tattatggtt atttagacaa tgactttatt atgtatgcag atgtaattta attatattaa 63360 aagaggtgtt taagtaatga taacgacata cattatattt tcaattttag tactaggatt 63420 agttaatatt atttcataca aaaaatcaaa agcaaaataa attaaaaatt ggaactaacc 63480 tttctatatg agaggttagt tcctcatatt tgattttttt tagaaataat tgcgttattt 63540 attatttcaa ttaatttatt tagaaggaga gatacattat attgataatt aaaatactgt 63600 ttttgatatt tttagtattg ggcaatattt tatttttaaa ttcattattt acaattatct 63660 ttaatgagtt tgatacatat aagagagaat taataatgaa tcttatatca ctgctatcaa 63720 tttttactgc attatggtta tactcattaa tttaaatcaa ctagaaaaat tttaatgttt 63780 ttaaggaaaa tttctagctt ttttataaaa aatttgttat aataaataac gttatagtat 63840 taaataattt ttggagagtg aatgttaaat gtcaaaatta actagcaaaa ttaatgattt 63900 gattaaatca aacccatcag tgtacggtaa agaagataat tacacgccta tgtatgaatc 63960 aggaattgac ttattggact atagaaatgg tttcttaaat actgttacag atgatgaacg 64020 tattggatta atgggcggta aagtaactac atttattggt ggatcaggtt caggtaaaac 64080 aacacttgct attcaagcag cagcaaaaat tgttgaaaaa tatgagaact caagtgttat 64140 tcattatgac tttgaagatg caactactga tgaacgtatt tatcaagtaa caggttggtc 64200 taaagaaatg aaacaagaaa aatacactaa attaaataaa aagattagtt tagattcagt 64260 agatcaatta attcgtggta tccgtgatac taaattagaa aatgaagaag aattcactat 64320 ccatacagac aaaattgatc cagaaactgg agaaaaagtt tcattcatgg ctccaacagt 64380 agttatcatt gactctgttg ctacaatggc ttctaaagaa attgatgata aagatggtga 64440 aggtggacaa atgaatgcca ctaaacaagc taaagataat acaacattca ttaaacgtat 64500 tattggttca tctacattaa attcagctaa tattatgctt attttaatta atcatattac 64560 aactaaaatt gatatcaatc catatgcagc tacacctaaa gaattaaact atcttaaaca 64620 aggtgaagca ttaccaggtg gtaaagcaat caactatatg gcgaataaca tgtttaagat 64680 tagtccatca caggctttag atccagaagg aaattctaat caagctaaat atggaattaa 64740 aggttttatc aatacagttg aagttattaa atcacgttca aatgcagctg gtgctaaatt 64800 tgatttaatc tttgaacaaa agaatggctt taataatgct ttatcaaatc tattgttctt 64860 acaaagtgaa aaaatgctta aaggtaatcc aagagcttat cgtattgatg gttatgatga 64920 tgttagcttt acacttaaaa catttatgga taaatatgag agtaataaag attttaaaga 64980 atactttgat aactatgtta aaggtatcta taaagaaaaa ttcttagcta atattgaaca 65040 tgaatctagt ttagataatg aagaattaga attagttgaa ttagttaata aatatgaaga 65100 tatttggtta ggttcagacg gtaattatta tgattctgat aaaaatgcta tagaagtatc 65160 taaagattaa tttttaaaag ggataattcc aatgaagata atatacttca ttggaaccct 65220 ttaattcaaa ttttggttca aatattatatt ataagatgt agaatattaa gagcatgata 65280 ttctacaaat atattcatta ttataggaga gtgtattaag atatgacaaa agacaaaaca 65340 caaagaatgg tagaaattga agataagcga agtcatgagt ttttatcaga acctctatta 65400 atgcctaacg ttaatagaac taatggtaac cgatcacaaa tgtttacatc tcacattggt 65460 caatgtattc aattaactgg agctgaacca cctttaattc aaactggttt tgaaaatcaa 65520 gtaggtaaat attcaactgg atacaagaaa gctaatagag attttgaagt tatttataaa 65580 tttgaaaaga ataagtacgt taattactat ttaattaagt acaaagataa tgatgaatat 65640 gatgtaatta ttagagaaga agctaatcac ttagctgaga agttcggaaa taaatataat 65700 aatgatgaaa ttgataaact aaaagttgga gatactgtta gtaaagaaac tgtattattt 65760 aaagatcaaa actatgatga agataataat ttccaatatg gtgctaatgc aacttctgta 65820 ttcttaccat tcaaaggtat gacgaatgag gacggaattg tagtatcaga atcattagca 65880 gagaaaatgt caagttattt tgtaaatgta atcaatatca ctatcaatac aaacgatatt 65940 cctttaaatt tatatggaaa tgaagatgag tataaatcat ttccagatgt aggtgaagaa 66000 gttcaaaatg gagtattgtg tgcaactcgt agattgaatt acgatgagat tattcataaa 66060 tttaaaaatg aaatgcttac taaaacatta gaagatgata atgcttataa agttcacggt 66120 aaagttattg atattgatgt acttaataat gaagatattg aaaaattaga aaatcaaaaa 66180 tattcagagc aatttgtcaa gtatattaaa gaattaagac acttttataa aacatttgta 66240 actgttacag atgatattgt acgtaaaaag aaatttagta atgacttaat tagaattcat 66300 aataaattta aaggttatat tgatgataac gctaaattag tttatgacaa taatcaattt 66360 gataaaatta tctttagagt taaagtttta gaaaagaaac ctttagttca tggatcgaaa 66420 atcaccacac gctatgggggg taaaggagtc gtagctgaaa ttgtacctga tgatcaaatg 66480 ccaatgatca cagagttcga tggagaagac ttcactaaag attctactaa aacaccaatt 66540 agtaaacgag tagatttaat ccataataat atgggcatca ttaaccgtgg aaatccatca 66600 gctttaattg agttagaatt aaatcatgta tcaaatgtaa taagacatcg tataagtaaa 66660 ttagatgatg ttaatcaaca gaaagaatat ctattaggat atattaaaga tgtagataaa 66720 atttcatacg ataattatgt taaattattt aatcaattag atttatctga aactaaagaa 66780 gctattaatg aaattattaa agaaggtatt gtattacatc aagcaccatt ctttggcaat 66840 attgattcag aacaattaag atacgtattt aataaatata atattaagaa aaatagatta 66900 aatataagta atagaacatt catggttgga gatttatatc acttaaaact taaacatgaa 66960 ccgtctggta aattaagtgc aaaatctctt gactttaaca attacagtgg aattcctact 67020 agaactccag atagtaaaaa gtatctatca agaattaata acaatccact cagaattggc 67080 gagatggaaa catctaatat gatgatcggt ggatctatta aagcaatcaa tcaattaacg 67140 aatatgtatt caaataaccc agatatgcgt aaacgtttat tagttgaatt gtatacaggt 67200 aatccattta agatcaatac agagagtata caaaaacgaa ctcaaaataa taatactaaa 67260 gtacttaatg cttactttag tccattgaat gttagtatga catttgatga acctgaagaa 67320 gatgaattac tagatatcat ggatttaaat gaagaccaat tagaattctt aatggaaaaa 67380 tacgaaaatt tagatgatat caatgattta acacctcaag aaataaatgg tttagttaaa 67440 gaaattattg aagaaagtaa ataaataaat gggagtaatg atcattattt tgatcattac 67500 tcctatattt aaaggatgtg tttaaaattt atcctgatta cgatgaattt ttaaagaaag 67560 aattagaccg ctttggaatt gatacggata gtatgatgta tcattctgat cttaattaca 67620 attattgtaa agagaaatta gaatcaattg aaaaggaaga taaagaaatg gaatttaatt 67680 atttgaattt agaagatata tctttaaata aagaagagac aagtggagtt atgactataa 67740 gagaattagt aaatactatt gatcacttga tatatacaga aaatgaagtt acacctttat 67800 actacttctt tatggataaa attgattcac ttcctatgat taatatgatt acttataaaa 67860 aggcagctaa cacatctat gaagaatata aaagatataa cactgaaaat cattcagctt 67920 atataaatat taagggagaa tggaaacagt tatcatttaa tcaatttaaa gaatctttaa 67980 aagaagtttt attatcttca cataaagaaa gcaatgttga taaattattt aaagagttaa 68040 ataatttagc tgtaaaagat aatttttcat aattgctctt agatcaaaat tagtaataag 68100 catatattat aaatatgaga caatgttcat taacttgatc attgtctcat atattgtttt 68160 attttttata aataaggaga tgaattggat aatggaaaat aatacattaa attcgtatat 68220 aaaggaagat tttaaatatt ttaaagatga taaattagaa attgatgaaa tatttaactt 68280 taaagatgat aagactaaag aaaaatttga aacgtttttt aatggagtta tatacacatt 68340 gaaaaatttg aattatgttg aattatctga aatgtataat gaatcaatta aagagaaagg 68400 taatactcaa gttaaatctg aaagttatat aaattattta aataatgaat tgaaaaataa 68460 aagactaaat aaagaaacta aaaaacttta taaagattta ttaatgactt tagaagatga 68520 tttgaaaaga tataatgcta atttagatga cagcattata aataaattat tcaaaaataa 68580 gtatatatca atatcttatt atagtttaat agtaccgtat aatattgcta acgaaattga 68640 atttaataaa aactattata tctttcttga attagaagat tttgttaaat tcatagtatt 68700 tccgtattat cagcttttat acctatctaa aaataattta agaaatattt atataaagaa 68760 tacagatata aatcttcatg attattttat tgatataata aagagttata ttaaaaattt 68820 aatagataat aaagatgtag atacactaaa ggatttatta gatgtgttaa caaatgagca 68880 cgaatatcta agatccccaa aatatacaga ctatagaaaa ggtaatggta gaaatttatt 68940 tgagttgcta atagatatga atttcaatga atttaaagac ttattatatg aaatgatata 69000 tattataatg aataataatc taaaaaaaga attacaagta gaaatgaatt atgatatata 69060 caaacacaat atatttttaa taagtttaat gaatgatgaa gtagaaagtc atagacaacc 69120 taaatttaat gataaatttt taataagag taataataca attagagcta ctgcaagtgc 69180 agatttatac agtaaaaata attactacca aaataactta ttaggacact atattaatga 69240 tctatatgta aataaaaata aaataaataa atttaaaagg gttaataaag ttagaagtct 69300 taaatctttt atttatttaa ctaaccaaag atgcattatc ggtggtgagt catattataa 69360 atatctatat aaatatttat ttgatccaag taacttaact agagaagagt ttgaagtatc 69420 tacattatta attaaattga taacttgtaa gtctagtaat caattaaaga aagttatgga 69480 gaatgcaaaa accaactcta tattaaataa tcttttattt gaaacagaaa ttaatgatat 69540 aattaaaatt ggtatagaaa tgaatattaa tactatattc aatgaaaagg gtttaagtaa 69600 aattaataca gttgatttaa ctgtaggaaa tattgtaaaa cctttgttat ataataacgc 69660 aaatgattat gaagaacaaa cagaaatcat taattcaata tttaaaaatt ttacttatga 69720 tatagatatc aattttgata aatatcatta caaagattta gatgaatatt ttgaaagtag 69780 attaaattta ggtcttttaa aagaatcaaa tatagatatt agtattaata ttaattatatag 69840 taaaattgca aaaactattg taaataatat taaagataaa cttagaggaa aatatgattt 69900 tgaaaagaat gagtttatta tacttatga taagatgaat attactcgtt taacttctac 69960 agagttctgt aatggtttat gtgaatattt aagtaaatac ttcccagaag aagctaaaaa 70020 gttaaataag agttttagag ctgaaattgt aaatacaatg tttagataaa aaggagaaat 70080 taaaaatgga tgttaaaaaa acgtttaatg cagatataat gaaaaatgat gaaaaggctt 70140 tcaatcatat tattaaaaat tgtatgtctt tttatgataa aagaaaaatg tataatgaag 70200 ttaatgatga caatgaagtt ttaacatata tatttaataa ccacaaagaa gaattaatga 70260 aaagaaataa tggtttaata gctatatcaa aagatctaaa agatcttatt agatacaccg 70320 ttgtcgatta ttatttatta agtttattaa gagattttc ttcattttca gttgggtacc 70380 gggatattga aaattttgtt gagatgttaa aaatggagtt atttaaacca gatcaagaaa 70440 ctttaagtca attttcttca aaagatgata taatatattt atattataat acaacactaa 70500 ataaaataat aaaagttgat cctattatgt acttaaaagc actaatggag tatgttaaag 70560 aagaaaaaga attctatgga gatctatcta tagaatttga aaaagaagtt aaaaaatatt 70620 tagttgaaaa gaactttaaa taaaggagag atgatattta atgaatggat atggaaaaat 70680 taataaaaaa gtttttaata tagatcgtag caactttgaa gtagttttaa tggactacat 70740 ggacactaaa cagatgaaaa ataattataa tagggatata accgatcaag aaaaaattga 70800 tcggttaata cctttaatta aacaacaaga aaatgaacaa gatgaaggta gaatatttga 70860 aaatgctaga agatatgaac ttcttttagc taaaacattt gaatactctc ttaatggaaa 70920 attagaatta tacaaattaa aagaagtatt aaattattac gaagaaaaaa atctttttaa 70980 tatagtatat ccaaatttta gatacacttt taatgtagaa tctcccagta aagagtattc 71040 cttattatct ttaaaaacta aaatattttt aattatagaa actattatatag attttattaa 71100 aaatgattat gtagaagata atctttctat taagttaatt ttaaattcag aagaaataat 71160 gattgatacc cttgatttaa acgaaaaatc tttgtgtaat acctttagtc tacaatatac 71220 aaatgaattg ttatcttata atggagatta tttgttctca catgatcaaa taaaacgtat 71280 agaaaatata aataatattt tatttaacga tatatacaaa gataaagata aagaaatttt 71340 agaattttta tctaagaaag taaaaaataa atacatttca aaatatttta aataaacagg 71400 agtgaatagg atatgtcaaa tttaactatg caagaaaaag acttaattat gattgaaaat 71460 aagtataata gatttttaga taaaaaggaa aagataatga ataaagaaac agactttatt 71520 aaaattgcat ttgaagaatt aatggacttc attgtacatt ttggtcataa taaattcttt 71580 aaatcagaca caatatttta tagagattat gatagaatgt tagagaatta taaaatagaa 71640 ttaaataaaa tatctaaagt ggaagatgat ttagtactaa cttatttaaa taaaattatt 71700 aatgacaccg ataaagatga attctatgat gaaatgaaaa gaatttcaga aagttatagt 71760 aaagaaaaat tagtcgtatc tatatcatat ataaaagctt tggacttcta tatacacatg 71820 atgcgaaatg aagaattaat gagtgatatg ggatctctta cagttcatcc ttatgatttt 71880 aataaacgat taataagtga atataaaaaa gataatatat tttggaaaaa actaagtgat 71940 gaagagaagt caaatgcaat tcaaatgtct aatatatatt ttgaaggtat tgaaaataaa 72000 gaaatcggta ggtctactac gaaatatata aatggtgaaa aagaaggaac tgtatttaat 72060 tttaatataa atacatttca taaatttttc gatcaatttg tatctttgga tatagcttat 72120 acagacggtt taatatttaa tttaatgatg aacagtaata tcagtaaata ttatgagaaa 72180 tactataaaa aaacagaaca tgatatcttc aatactagtt atatttctga taaatatgac 72240 tatgaaaact tagaaaaaga taaattttta aaaactttaa atcgtataga tatgttttat 72300 gatataaatg tacctttata tatttataat agtgaagatt tatcaaataa aaaatactat 72360 aattatctaa ctgctatgaa gtcttttgct ttaaatgatt tggttaatcg ttattatgat 72420 tcttatgaat atatagaata ttttagcgaa gttaatgtca atgattcttt cacgttagat 72480 atgttaagtg acgatgatga aagtgaatca aattattttg aagaattgtt taaaaaaata 72540 aagaaagaaa atgaagaaag acaatggtta caagcttttt aaaatttatt taaagagaag 72600 aggagacaat ttatgatatt tttaattggt atattagtca ttattttaat ttggttggaa 72660 ataatatcat tttctttatt tatatcaagt ctgataagtt taccattttc aatatttgac 72720 acaggaacaa gtgattttat taaagaagat ataataacag cgtttctatc aggtttatct 72780 accgtcataa tctttttcat attatcatcg ttctaataaa aaggagagaa cattatgttt 72840 gctttattgg gaatattagc aataatattt ttattattaa tatttatagg tttaccttta 72900 tttgtcatgg gagtagcttg catatttatg tcactttatg aaatctttgt agaaaaagaa 72960 aaagatattg atatgctact gacatcaact tatataactc tcggttcatc aatggcatta 73020 ggtttagcta tctttatatc attttgtgtt gaaagcatgt aatcatttaa aataaaaagg 73080 agaaatatta tgttaaaatt taatgaaatt aatgaaagta atttagatga cgtacaaaaa 73140 tatttagagg agcaatctta tgtatattat aatacatcag atcaaccaga attaactgat 73200 gaagaatttg acaaactatt aagagaatat gaaaagttcc gtccatttaa tggcggtgct 73260 ttaccttcta aaggtaaaaa attagtagat gtttcacatg aatatcctga attagtagga 73320 acagtttcta aggttaattc agttgaagaa ttagctgaat ggattgaaga aaaaggatta 73380 attaatagag aattattaat tacacagaaa tatgatggta attcagtatt agtcatttta 73440 actactaaag gagattattt agtaactaaa tcagcattaa ctagaggtaa agatggtaaa 73500 ggtgctgact taactgactt cttcagtcat attaaaatta aaaaatcaga tgtaaatatt 73560 aatgcagtcg atttatctga agatgatatt gatatcgcta ttaagtgtga agcagtaatg 73620 agttatagta actttaataa gattgatgaa gagtatgcta accctagatc aatcgttgca 73680 ggattattaa actcagatga tggatataag aaacgtaagt taattaattt attaccattg 73740 agaatcaata ttagtaataa agaattaact cgacaagaag aattgaattt aatttcagca 73800 attactagtc atagtactgt atttgatcaa cttgatccac agtataattt tgttatggaa 73860 gatgaacacg attataaaga ctttaatgaa ttatatcatc aaatagctga tgaaagagag 73920 tattatgaat acatgattga tggattagtt attgaagctc ttgatgaaga tgatagaaat 73980 cgtttaggca gattaaatga tcgtaataag tttgatgtag cattgaaatt cccatatatg 74040 actaaaaaga ctaatgttat tgatattgaa tttgatgtat ctgagaacgg aactggacgt 74100 tacacacctg tagttagatt tgaacctatt tattttaatg gtgctaaatg tgaaagagtt 74160 tctatttcta actataaacg ttttaaagaa cttcaattag ttaaaggaca agaagttatt 74220 attgaatatc gtaatgatgt tttgagttat ttaactccat ctcctactaa cgaaattact 74280 ggagaaccta taccgttcat taaagagtgt gtatactgtg gtgaagaact tgaagttaat 74340 gaaaatgaaa catttgtatc atgtattaat aacgattgtg aatgtagagt attaggtatt 74400 attaacaact atgtagataa aatgagtatt aaaggaattg aatattctac tattaataag 74460 ctttataaag gtaacaaact acctaacgga atccaaagtt tatatgaaat tgataaaaac 74520 gatattatgc aagtagatac ttttaaagaa aaatcagctc agaatattat taatacaatt 74580 cataaaaata aagaatatta tgactatgat gtattaggtt cattaggatt aaatggagtt 74640 ggaagaacta catttaaatt agttactaaa gtctatgatc cacaagaaat agattataca 74700 gattaagta ttaaagattt aacttctatt aaaggaatcg ctgatattac tgctgagatt 74760 attattaatg gttataaaca gaataaagat ttaattgaat tcttatttaa tgaattggat 74820 gttaaatcac ttaaaaaaga aatggaagct aataaagatg attcagttga gccaatgaat 74880 attgtattta gtggatttag agatgctgaa tttaaagaac agttagaact taaaggtcat 74940 aaagtaactt catcagtttc aggtaagact gattattag ttactccaga tccaaattca 75000 ggttcatcta agattaataa agctaaagaa aaaggtatca agatcattga tattgaaagt 75060 tctaaaggtg agttgttata aatgaaatat tataaggtta attataatgg tatattgaaa 75120 atattgaatc tagatgattt tgaagatgat agaattattg aaacacttag taatattgag 75180 ttatatttaa aagaagatga agaaattaga ttattggatt tatttaaaaa gccaactata 75240 gcaatggaca ctcgaattac aaaagaaaaa gataaccttt atatgaatgg tcatctcttt 75300 ttagaagttg agaatgcatc atgtaaacta tggagttacc atattaattt aaatggtgac 75360 gaaacattaa atgaaatata tgaaaggata tataacggat atgataaaaa tttctctttt 75420 aataaaatga gagaagatgg tctattattt ctatatgaat atgaacatta tacagaaata 75480 tctgaaaaag aatataaaga aaataaagtt aaagaaaatt ttaaataaaa aaggagattt 75540 taaattatga aatattacaa actaacagac agaggtattg cggatatatt taatattggt 75600 ggaatggatt atgaatttat ggatttctat gaggacaata atcacatatt cagaaatgaa 75660 agtctttatc taagagagga tgaagtaata cctctcttca gtattattga atatgatgtt 75720 actaaagaat gtgtaataac taaagaagaa ggcaaattag tcgcaaaagg taaaactaaa 75780 atagacgtag aagatgggta tgctgattta atttccattg atttagattt taatgaagat 75840 aatacaagtt taagcgattt atataaacag ttagaagagt actgtgaaaa tgaaaaattt 75900 gtagtgaaag atcgtataga aaaacttttc gagggttctg attataaagt tgtcactgaa 75960 aaagaatata aagaaaataa agttaaagaa aattttaaat aaaaggaggt attaaattat 76020 gaaatattat gaatttaata aaaagggaat tattaaaata ttaggattgg acacagctta 76080 tttaaaagaa gatgaagata tttttagaga aggaaatctt tatttaaaag aaaatgaatc 76140 aataaagata aaagatatta taacaaataa aaaagatatg gagtttaatt gcagtattta 76200 tgaagggtct gaagataact cattaatgaa agctaattta actttcagac atggatcggg 76260 acaactttta ttgaatattg aatatattga tttaaaagaa ataaaagatc gcactgttga 76320 agaagtttac aaatacgcta aagatttagt tttaaataaa acattttctt ttaataaagc 76380 tgaagagctt ggtatatgtt tatatgaagg aaaagaatat gaagaaatta ctgaggaaga 76440 atataaaaaa tacaaagtag aaaatacttt taaataatgg aatgagttgt tattgttatg 76500 gaaaaatatt ataaattaac agcggaaggt atatttgatg ttttcaaatt agataaaaaa 76560 cacattatat tcccagaaga taaaaataca ataatagatt tcagatcaaa ggaagaacgt 76620 atagagaaaa ttaatgaact tatatacttt aaagataatc aagaaataac aataaactca 76680 ttatctaatt taacagacaa tatcgtaata gataaatcag gttctaaata tacatttaac 76740 catttaatag aaatatcatt cactactttt agtcataaaa aaagatataa caaaacaatc 76800 aatgtaccga atgtatttaa aggaactgta agagaaaata gtagtagaag tgccttagat 76860 ataccgatag atatcaacaa tattgataaa atagaattaa catttaaaga atatagagat 76920 ctagtaataa aagaaacttt taaataataa ggagatttta taattgaaat attataaatt 76980 aaataaggat ggttatatta aatttttagg gttagatgtt ttgcctggac ttaaaacctc 77040 aattgttgaa aaagaaataa aaaataaaaa cttcattgtc aaatattgca atggagcaga 77100 tttttgtttt acattagatg aaattaataa aatgaaaaac aaagatattt accctaaact 77160 tggatttgaa agtctaactg aaaaagttaa tcatgaaata gaaaataatc caatagtatt 77220 tgttaataga aaatatgaag atgctaaagc tttaattcat gtagatttaa ttattaataa 77280 tgaagaaact acattaatga ctatgccaag atttaatatt aattttttaa atcataattt 77340 gtatatggaa cactttgatg aaataacaga gaaacagtat aaaaatatta tggtaaaaga 77400 ttcatttaag taaaactcaa tttaaatata tattataaaa ttgtgaaaga tgtatgatac 77460 ttatacatct ttctaaaata tttatttaaa gagaggtgaa aaagataatg agttctaatt 77520 ttgattatta tatattgcaa tcgagtattt cagaagctag aaaaaagatt aagaataatc 77580 tagatgtaaa tggatatatg gttataagac aaatattttt cagtcattta gattataaag 77640 attattataa tatgtatcat aaagtaaata atgtagaaga ttattacaat gatattatat 77700 tagaaagtat taaggatatt atatttgatg aagaaggtaa acttaatgaa gaagtagcat 77760 ttagtttaat taaaggttct aattcgaata tatgtgcttt aattaaagat aataaaggta 77820 attacaaaat ttataaaaaa gataaatatg taattaaagc tatagaagat ttattatctg 77880 agaaagatta taaaagaata ttggttaaaa atacttttaa ataatttgaa agtggatgca 77940 acttactttt attatattac aagtgagagt tggtgatttt attgataaaa atgcatttaa 78000 taaactttca aaaaaggtct atgaatagtt ataagaagaa tttaaacaca attgtacttt 78060 tcatagatta tgataaaaat attttcaacc aaattaataa tcaattagat atagatgtat 78120 taggtaatga tactataaga ttaaataatg ctaattattc attaatgtta gatgagaaga 78180 tttttagttc tgaaaggaca acaattgatt tctataataa aatagtaaat aatgatatat 78240 taaatattat taaagaaaat atatctaatg tagataatta ttctaaatta aaagaaatca 78300 ataatatgac tgatagtgaa tttaatgata ttattaataa agataattta tttaaatgtc 78360 aaaataaata cttcagtatg aataaaatac cttatataga aaaagaaata cctgaaagtt 78420 tttatctaga tcattttaaa gagattaatt tagattttat atttgagaag ctttttgaag 78480 agaatagaga agatgaagaa aaattaaagt acgtttatac tttagctgaa ttatttctaa 78540 cactcaaaca aggtaagaat atattttata attataataa agaggtagat aagaaatatt 78600 atagatctat atttataaat tctttattta attaatatga taagaaagga gagaaataat 78660 atgaagaaaa tatacggatt taaaataaaa tataataaaa aagtggtaga tactttcact 78720 tttgaaagtt ttgaagaagc tatgaataaa ctagaattat cattattaga aatttatgac 78780 tcagaagatt ttacaactat gcaattaatt ttaaacacat atgacattga agaaattaat 78840 gaagatagtt ttaaagataa attaagacta aatcatctta atcacattaa gaattttagt 78900 attgaattgt tttctaaata tattaacaat aataaggaag aaggaattgc gtaatgttcg 78960 aggaaagtaa agtaccattt tcatttattt ataaagaaac taaatacttc ttacacagaa 79020 gaaatattaa gaatttccct aatggagatt ctgaattctt attgtatgga gatgaaaatg 79080 ggaagtcatt cataatagaa gaaagtaaat tagaaaactt aattgaacaa catgaagttg 79140 aagtatctta cgaagaagat attatttaaa tatattattat taaattgagg taatgacata 79200 ttatttgtca ttacctctaa tatattaaac aatcaaagga gaaaacaatc atgaagaaat 79260 ttttagtatt accattatta ttcgttttat tattaacagg gtgttctcaa gctgataaag 79320 ttagtcagaa tatgtctgaa gaatcagata attttaatgt agttagaaaa gtaactgtca 79380 ttaatgcaat taagaatgat ataatattcc aaatgtctgg acgtatgtct attaaagcag 79440 acaaggaaga caatcaattg gagataattg tggaaaatga agatggtaaa tatcaaaaac 79500 atatcattgg tttatctgat aatgtttcat atactgttga agatgttaca actaagaatg 79560 taagtaaata tcaatatgaa attaattata atcctaaaat gtggattcct gcaaaaccag 79620 attataaaga ttaatataat agaatggaga gattgattta tgtctaagaa aaagaaatta 79680 gaaaaaagac ttaatgtaag aattaatcaa gaacaaaaga aagctatttt aaaacgtgaa 79740 gatattgata gaatggattt tgagttcatt acattagata aagagaaaca tgatgaagaa 79800 gaaaaatttg atatcaaagt aaaatctaac gataagtttt ctctaattat cattattaaa 79860 ttcttttcta aattgttgaa ttttagtatt aaaagagata agaaaaaaga aaaagttaaa 79920 gaagatataa aagatgataa tgaagtttct aatttagata agaaataata aaaatgccat 79980 aatacacaat ttaagtgtat tatggcaaat tatttatttt tcaggtttaa aacggtcttt 80040 aagtctagga tatagacgta gatgtgcttt acgagtagga tctgtaacaa caatttgatt 80100 tgttctagga tttctacgtt tacgcatatc ttcaggttta acttcaagga caccaatttc 80160 aggaataata gttttagttt gatcagcatc atttgcagat tcaacaatta tttctatcat 80220 ttcattataa gcatcaacta gttctctttg tgttaatcca gtacgtctag accattctct 80280 aaagaagtgt ttttgatctt gaatttgatt tagcatttta ttatttcctt tccatataat 80340 atatttttaa ttttttagaa aattgttaat attttactag cttttttcta aattttatga 80400 tataatattg ttatggaatt tcatagttgt aaaaaaataa ttttttgcaa taacttaaat 80460 ttttatatgg tttcgaattt ttaattataa ggagagtcag atatcgttgg gtaattattt 80520 aagaaaaatt acgaagaata tacaagatga ggtcagtaca aaagagtcat ttaatgagga 80580 tgtaatatac tttagggaga atgaaaacct agaagatatt atatctgata tttacaaatc 80640 agtagaattt attaaaggcg taaaattcat tgattgtaaa gttgttcctc caagtgaagt 80700 ttatgagtac aatcaaatga cagacaaaca atttaaagca agagatttta gaaaaatcaa 80760 cgtagaagaa tcaaaactat tagaagttca aattactgta gaatttgaat cagctgaagg 80820 ggaaaaagaa ttatacacac ataaattaga tttccctgaa cttatagaag gtcagtatta 80880 ttatattaat gataataagt tcttccctat cttacaatta gctgatactg aattctataa 80940 acctaaagca agtacagtag taatgaaaaa cttattacaa ccattatcag taaacggttc 81000 taaaaaagat gaacttattg atgatgataa gaaaatgcct aaaaagttaa gaggtagaac 81060 attatattta gaagtgttta ataaaaataa acctgttcca gcatttttat tctttattgc 81120 taaaatgggt ctagatgaaa catttgaatt cttagatatt aaagaatatt gtgaattagt 81180 agataccaac gatgaaaaag atgataaaca ctactatttt agaattaata ataaaataac 81240 tattcaagtt gataaagaat ggttagatca agacgataga tatagaactt ctatggtctt 81300 atgtattaaa gatttattta aaggtatgag agcaggatta gataaagtat atgataaaga 81360 attctggctt aagaatttag gatctgtgtt tagtggttct actaatgttg atactaaaat 81420 tgaaaaagct aattctatga ttttatcatt tgatagaatt ttagatagtc gtactaaaaa 81480 tatttctaga tagatccag aagataaaga atcaacttat catgtagtta aatacatgtt 81540 taaaaacttt gataatctta atttattaga taatacagat ttagctaata aacgtttaag 81600 agtattagaa tacttaactt atccactgaa tagaaagaac tctgatacgt cttatcgtat 81660 gattaatttc acagataaga aacgtacaat taaaaatctt aaaggattat tctcaggtgt 81720 acctcgtgat ttcttattaa aaactatagg aacatctgaa ggaattagat attccaatgc 81780 ggttaataca attgacttat ttactagaat tcttaaaatg actaaagcag gtccacaaac 81840 tgctgttgat actagtaaac catctattag aactattaat atcaataata cttatttcgg 81900 tagaattgat ttaatagcaa catcttcaaa caatccaggt attacacgta cattaacacc 81960 attctgtgag gttaaagatc ctggtgagaa tggttcattc tattttgaaa ataaacctaa 82020 catcagagaa aatattgaca cagataattt agataaacta gagaaagaat ctgaagacaa 82080 tgaagttgta ttagatatta aagaaattgt agaagaggat gacgaataat ggctagattt 82140 ttacttaaga ataaagactt atcaaaatta ccagtagtaa caaatcatga atcaattgat 82200 aagaaaggtg atttcactga agacggtatc ttcagtgaga aaatctttgg acctgattca 82260 gatgtagata atattacaaa tgaagctata gtttatttag gtaataacta tattattaca 82320 cctttaggat atgacagaat taaaaaatta ataggtagaa aaagatttgc tgagattatt 82380 agttctgaaa aacctattga tgaaaatggt aatgtaattg aaccagaaga tgaccataat 82440 tcatatattg gtttagttga atttagaaag aacttcttaa agattcttaa agaagaagtt 82500 aaacgtgata aacgtaaaac taaagattac aatagagttg ttcaatggta tttaaatgga 82560 acattattcc aaaattatgt aactgtattt agccctaaat taagaccggc tacagttaat 82620 aaagcaacta agacatttag acattcagaa attaataaag aatttaattt attaattgct 82680 catagtaata gtcttaaaga attagatgaa cattatacag atgattcagt tgaactacaa 82740 aagttaaacc tacttaataa aattcaagat gacaacatga atatctatga tcgtattatc 82800 aatgaaaaca ttaaaggtaa aatgggtact attcgtaaat taattatggg tagtcgtgta 82860 ggatattcag ctcgttcagt aattgttcca gctcctgatt taaaattaaa tgaaattaga 82920 atgaattata caatcttctt agaaatatac aaaccactat tagctaattt aatgtatgta 82980 acggaaaata ttccattacc taaagcagaa gaaatattag gtagagcttt agataacttt 83040 aatcctaaag tatataaata tatgaaagaa ttagttaaca aaactgaagg tggaatgaga 83100 gtaattttga accgaaatcc atctatctca gaatcatcag ttcaaatatt aaaaattaaa 83160 gatatcatta gtgatattga ctcagctgta gtaggtatta gtaataatat acttgcaggt 83220 atgggtgctg actatgatgg agacacattg aatattatag ctctcttctc agaagagcaa 83280 tatgatatgt taaaagtaca agatccagtc aatcaattaa tatcatataa tgatggtcta 83340 tttaatagaa cttattcact taataaagac tcacagattg cagtttattt attaaataat 83400 cctaaatcaa aagatgtaag tataaaagct agtaaataga ttttttagaa taacggtctt 83460 atcagatcgt tattcttatt aaataaatat gactggagac attgaccatg aacaaaagac 83520 aaagaaagaa attagagaag aaaaaattag aagaacaaag taacgaaaaa attatagatt 83580 tgtcaaaatt aaaagaagaa aaggatgaag ttaaaatgaa taaagaagtt aaaagagaag 83640 gatcttacaa gaaattaact aaggaacaag tacattatat tgcagaatta attgacaaag 83700 gacacggaaa cacttatatt ttaaaagaac ttaaagctaa gtttggtatt gaccgtaaat 83760 cacatcaat cacacatatt agacgtggtg aacatcctac atttaaagca cttacagatg 83820 acaattatca ctttgctgaa gtgggatatc ctacatttaa tgaatacaaa aagattttac 83880 gtggagaagt taaacctaaa agtaaaacac gtgtaaaaac tgaagaaacg gttaataaag 83940 taaaagaatc accagtagta gaaaaagtat ctagtgttac agaagaaaaa gtagaacaag 84000 taaaagaaaa aatgagtaat attcaaaaag ataaagaaac tggtaaagaa tatcgtgata 84060 aagaaagtat tcataaagca ggtaaacctc aagaaactat ctttgataag attatcaaac 84120 gtgttttaaa tattttataa tagaaaagat gataagaaat gtccaaatat gatttaactt 84180 tatatcatca tttaaaacaa gaagtaaaac catgtagatt aacaacttca caggatgaga 84240 caatgatacg ttgtccgttc tgtggagatt ctaaaaagtc taaaagttca acacatttat 84300 atatacaaaa tagaactcca tttaaatatt tctgtcaaag atgtaatgct tctggagtta 84360 tgagtaataa agttttagct atgttaaata gtggtaatgt agaaataaat agttatatta 84420 acaatcaata taatgaatat atttctaata tgaataaaaa atatggcaaa tcttttatca 84480 atagaaatac aaaagaatta aaatactacc caaataaata taccgattta gaaataagaa 84540 agattaatta tattaatgaa agattgggta ttaacataga tgagaaggat attgaattat 84600 ataagattat tttaaatata gaagattttt ataagaataa tgaatttgat atagataatc 84660 aatatcaaat aaataatctt aataataatt attttagtta tatgttgaac gataagaata 84720 ctattaattg taggttaatg aatagtaata catttggggc taatgggaag aaacatttta 84780 aacaaaaaat atttaagaac ttagctgatg aaagtactag attctattca attaaaaatg 84840 aattaagatt ggatagaaga gtatataaca ttcatatagc tgaagggttc tttgatatat 84900 tggggatatt taatcatgtg tataataaag aaataaatga caatgatata tttatagcta 84960 ataacggaaa aggttataaa tttgtattaa attatctaaa tagtttaggt atacttaata 85020 tgaatataaa tatttattcc gatagagatg ttaaaattac tgattatcgc agtaagagaa 85080 tgctcggtaa ttcgctacca gtaattttaa atgatgctaa tatatattat aatgaatttg 85140 aagatgagaa agattttggg gtaacaaaag ataaaataaa attatcagaa ccaattaagt 85200 ttaatcaata aataaattta tattataaaa gtgaggtaat ggatattata ttcattacct 85260 ctaatattat ttacactagg agagtgaatt ggatatggca aaagaaattt ttagttcaga 85320 agatattttt aaggatttaa cagattttca cacagaaagt agattagagg aatttagtca 85380 caagaatatt ttaacgtctt tattagaaaa tgcagatagt aaaaataatt tagaaaaaat 85440 aatattgatt ctatctataa atattaattc atctttaaaa aatttaaatt ctattgaaga 85500 tgaaatgata gatgttttta gtaaagaaat agatattaag aaagataaag ataatattga 85560 tttgctatta aaaaatctta gaaatgttaa agataattca agtatggaag acattaaaga 85620 atatttagta ttagaagtat ctttagatga ggttattgat aaaattaatg aagatgattt 85680 ttataatgaa gaagtaaaag atttatatct taaattctat aataatcttt ctattttaat 85740 tatatctttt aaattgttaa cattctataa tggttttaat aatgtagtat cttaattaaa 85800 tttaatataa ggagaatgat tagaatgaga gataaatttt tattatttga aaatgatgat 85860 aatagcatat atatgctatt atcaaatttt aaattcaata aagaaattaa aatagattat 85920 acacatgata taaaaaatat cgatgatgtt cctaagtatt ttaataaagg aataaagaga 85980 tttaaaatga gatatgactt tcattcaggt catattatta gacaagatga attttacaac 86040 tacatggata atttagatgc tgattttaaa aattcaaatg ctaaagcttt agagaaaata 86100 actttctcta atcttattag tgatgataaa atcaatatag tatatacagg taagaaagat 86160 gataataata aaattgtaaa aactaatatt tactttattg tccctgttag tattatttct 86220 gaggaattaa attcaaatct aatatcgtta gatattacag ctatgaataa aagattaaat 86280 gatgtttata aatctgaaac aaccaatcag aaattattag ggataaaacc tagtgttaca 86340 aatatcaata ttattgatag acaaaataaa attattaatg aatactttag agatatagga 86400 gtagaatata actttattaa tgattttagt aaatcagaag aataaaggag attatattta 86460 tgattgaaga agcttttaaa ttaaatttca taagtctatt attaaatata ccttactttt 86520 taatatcaat ttacttattt tattattttt atacttacaa gaaaattaaa aataataaag 86580 atgatatata cgatgtagct ccagtggctt ttacaagtta tttgagtata ataattataa 86640 ttatactcaa attatctact aatagtttat ctcaatatgg taatttgata tatcatcctt 86700 ttaaaatatt tactttaatt atagtaggtt taataatgta tgtggcacta gatgcttcat 86760 tattatatt tgataagatg aaaagttcat taaaaatatt cattgtattg aatatctttt 86820 taatttcatt attaatatct gattcattat tatttaatat gattattatg atagtcatat 86880 caattctatt aattttaacc tcattatact ttacagttga tcatttagat agtaaagata 86940 aatatgtaaa aataactttt tgcacattct ttactttatt ccctctattt ttatcattgt 87000 taattataaa tatggatgta attaaattta acttaataga tgttaatact aataataaaa 87060 ttgataatat gcatttaatt ataattgtac aaataatttt actagtatgg aatttagtag 87120 taatgatatt caaaatattt aatatcaata tatacaccgt tatatcagaa ttatttaaaa 87180 gaaataaatg aatattagga taatgatcaa attaatggtc attatcctaa tatcattttc 87240 tttttttgta actaccatta ttttagatat atattataat tatgaaggga ggaatatagt 87300 aatgatattt aatattctaa tagcattagc atatgtggca cttgtttctt taggattagg 87360 tgtttcagct ttttatatat ctttattttt attaagatat ataaaaaata atattatcaa 87420 gaaagaaatt aaaaatgaaa atagaaagtt attttatctt tcgttattaa tagttataat 87480 attcatgtca ataaaatcat acgttgatat aaaattaagt attatagaac aaatattaaa 87540 aatgtagaaa agcgtaacat aagacatttt aattatatat tataataatg aagatattat 87600 aatattaatt atatctttaa taaaaaaaaa gaggagaaat taaaatgaca gaatttgaaa 87660 atgaaactaa agtatcaaaa gaggagaaga agattaaaag atttattgat caaggtattg 87720 ataatttatc tgatacagta ggagaaggta ttgaaggtat tccgttatct ttaactgatt 87780 attttcctaa aataaagaaa ttaattatta aattaattga tagagaggaa agtgatgaaa 87840 ttaaaatgac gaatgaatca ggtgaagtat ttaaatttaa tagaacttca catgatattt 87900 atttaacagc aatcaaattt taaagaaaat tttctatgat ccaaaaaaaa aaattaaagg 87960 tgtggtgtat atgattaaag tcaatgaact attaacacaa gttaaagaaa taaaaacaaa 88020 tgacagttat acgaaattag taaacgagta tagagatatt atcaatgaag aatatatatc 88080 ttataaacca ttaaaagatt attacaattt cattatatat tatttagaaa aatctagata 88140 tcaagcattg aaatctaaca attttgatga atctaattta aatatcaaaa cattgataga 88200 cgatctaatg acattaaaca atattgttaa atctgatatt tttgatacta aagaagtaat 88260 cagatctact ggttttaaat taacaaatgg tagtacattt gatagaatta ttaaatacat 88320 taaagataaa ctagataaat taattataga gataaattca gataattata aatatcaaaa 88380 tatctatttc tatctacctg agctaaataa tctattgcat aatacaattc atatagaacg 88440 tgttttagat aaaaataaag ataatgtaga tattattaat atagataaat ataatttatt 88500 tgaaatgatg ccttgtaatg atattatgga taaagatgaa ttttatataa tggttaatca 88560 tttatatgat ttaggatctt tagaaaaagc gtaacgtgta ataaaataag tatatattat 88620 aattatgaag aaagagttta tcattaattc tttctaatat aaaattaaat ggaggaattt 88680 attatgaaaa agaatttagt attgaaaagt gtagcaggtc ttggattagg tattgtatta 88740 ggtgtagtaa gtaataagat tgacgacatg attatgcaaa aggaaatgga aagacaaatt 88800 tttgaaaaag cttcagaaat gacttttgaa catccgttcg ctaatttaaa ataaaggagg 88860 aaagaggata attgttttaa aggtctaatg aaaatggatc aagttcatta ggtctataat 88920 tttctatgat ccaataataa aaaggagtta aaaacaatga ataacaaaac taaattagca 88980 gaattaagaa aagaattaaa aatcgtatat tcggatatag gattgagcaa aacgagtact 89040 gtagaagaaa gacttcacaa gaaaaaagaa agattaatta aagaaattaa tgaaatagta 89100 gaaaaagatc aaaacatttt tgatagagaa aaacatatag caaaagttaa agaccgaaat 89160 aatgataata tttacaaagg ttcagatgaa ttttctaagg caggtagact tcatagaaaa 89220 tatcaaaaac aagataaaaa cagaatattc aataatccgg tacaagatta aatattcata 89280 taatcagttg aatttgaaaa agcgtaacaa tatggttttt aattatatat tataattatg 89340 aagaaagagt ttatcattaa ctctttctaa taaaaattaa aggagaaaaa ttattatgaa 89400 aaacttagta ttgaaatcag cagttggatt tgcggcaggt attgtattag gattagtgag 89460 caataaaatt gatgcgtaca cattagcaaa aattgaagag aaagaagtat tagataaagc 89520 agatagtatt attaataatt aattaggagt tgaaaaggat aattgattta aagacctaat 89580 ggacacggat caagttcatt aggtctataa ttttctatga tccaataata aaaataaaaa 89640 tgaaaagagg aaattaaaat gttagactta ttaaaaggaa ttgaatttgt aaatgaaaag 89700 gaaattaacg aagagaaaga attattaatc aattattcag atgaagcaag atatccatct 89760 gaacaagctt atagagaaat agattcaatc atcgaaagtt tcgacaatac agctttcgga 89820 ttaagaaaat ggggagtgta attagaatgg ttagagaaga aaaaatcaaa caaatgaaac 89880 aagaattaca aaaaatatta gataaagaaa ttagatttgg ttataaacca atttctaata 89940 gagactttga aaagaaatta aaattaatga aacagataga caagttaaaa tttgacatta 90000 gatctgaaag atatttaaga aatgtcaaaa agaacaaaat aaaggagtat aaaggtatta 90060 gcgattatgc aaaagctgga agattacatc aatctttcca aagtaaagaa gagcataatc 90120 tatggaaaga agaattagta attcaataac ataaatggag gaatttatta tgaaaatttt 90180 aagattaaaa actgaatggg cgttagtttt aggtatgata ttaggttcaa ctattggttt 90240 aatgtcaaat gatttctttg taggagctac aatttctatg ttgacaccaa taattactat 90300 agcaattaat tatgtaattg gtgatgaaag aaaatctaaa atccaagaaa gtaataaatt 90360 atactatatt agaatgaata gtgaaaaagg agatatattt aaataatgaa taaagaaaaa 90420 agattattga aactaaagcc atggatatta ttttggttta ctcttataac tggttttatc 90480 ataggagaaa tgattggata cgtagaaggg aaatcgttat ttttaggttt aattttgtct 90540 ggaatatgtc tatctatcaa ttatgttata ggtgaaatta gaagagatgg attaagaagt 90600 gattaggatt aaatttagat tattaattaa ataataagga ggtgcttgga tatgttatta 90660 gaaaactttg ttacaattat cgtgttactt ggtttaatga aatttacagg ttgttttaaa 90720 tttatgaaag aaatctggtc taacaaaggt aacaaataac aacaaaagag tggattattt 90780 ctatgatccg ctctacatat ttaaattaaa aaaaaaaacg aaaagaggaa attaaaatga 90840 aaaaattatt aatggtgtta gcattaatcg ctttaatcgc agttatcgga gcagcaggaa 90900 tatttggtta tagtagtttt aaaagcttaa cagtcaataa agaagatagt aagactgaag 90960 aagtatctaa aaagaaagaa gacaaaaaag aaaagaaaga acaagaagaa tcagataatg 91020 tagaagtaaa tcaacaacaa gatcaaactc aagaagtaaa taataatgaa cgacaaaatc 91080 aaactacaga agatagtaat acaaatgtac aacaaaatca acaacaagaa ccagtagttg 91140 aagagaaaac tcaagtaaca gataatgaag gtaataatat agatgatatg gattcagaag 91200 aatttatttc taaatataca gaaggaatgg atgaagaaga agctcaaaca gtaaaagaca 91260 tggctgaaga agattcagga tatgaagatt tcttacgtgg acaagtagaa gctagacaaa 91320 acggacaagg cggaaattac tgataagaag aaaagagtga aatgaaatga aaaaaatctt 91380 aagtatttta acagcgatag ctttaatcac agttattgga gcagcaggag tattcggcta 91440 tagtagtttt aaagaattaa ataatagtaa agatagtcat aaagttgaaa caagtaaaaa 91500 acaaaaagaa tcagatgata aaaataacac tcaacaacaa gaacaaaata catcaaaaga 91560 aaacaacaat atccaacaac aatcaaatga agatagccta acagaaaata tggatgaaga 91620 atataaaaaa caacaggaaa tgtatgaaaa gcaatcaaaa ggtgaagctc cagaaccggg 91680 ttctataatt ggcaacccac caaaaaatta tgaaactcca gaaaaagata aaataactat 91740 aagtgagtta agagaagttt taggcgatga tattgatgaa agtaaaattg atgaagcaaa 91800 agcgtctggc gaatatatta atgatgaaga ataaaaaata aataaaaaga atagaggaaa 91860 ataaaatgaa aaaattatta gtagcattat caatcttagc agtaattgta gtattagcag 91920 cggcaggtgt gtttggatat tcaaaatata aagaagcaga aatgaaacaa cataatttag 91980 aaacacaatt agaagaaaaa aattccaatg agcaaactaa tgaaaacgat caacaacaag 92040 aacaatcaaa tacaaatgaa tctcaaaatc aagaaaatag ttcaacaaaa gacaataacg 92100 acaataaaca aaaagtatct agggacaatg tatttgacta tgctttagct gcagtaaatg 92160 aagtaggtga cgctgattta atgaaattcc aagaaccttc ttacagtgat ggtgtatgga 92220 caattgacgc taataataaa tctggttcag ggtctaatac tataaaagta tacgatgatg 92280 gctgggtaca gatatatgat ggatctggtg aaatagctca tgaaacaaaa atagaactat 92340 aattattaag gagagttagt gatatgatca aatcaataac aaaagaagaa ttagcttttg 92400 ataaatttat ttcagattta gatttaacta acgtgtatga tagctttatt attaatctac 92460 cttctggacc taaatttatc agattaaacg aatttgatga aattgaagta tatgagaagt 92520 atgattcaaa tttaattaaa atagtagata tagatggtga atatgatgat tcattttcac 92580 tattctttaa aatcacaaaa ggaatttaaa atattatagt catgaatcta tttaagtagg 92640 ttcatgacta ttaattatat atttttttat aaatataaga aagagagatg acattaattg 92700 tgtatgaaat ttcagtagct ctaatgtttt taattataat atatttttca ttcaatacaa 92760 tatataaaac attagtaagt gcgtataatg aaaaattaaa aggaaaattc ttctctacat 92820 catttttcat ttttagttta ttgtttccaa taatgattat tgtattttac aatatagacg 92880 ggataaatat taaaatagaa tatgttttat tttattttat actattaata attaactttg 92940 tattaaataa atttcttaaa gttcatgata ttatagtata tacatcatta ttctattctt 93000 tatttataat gaattatcat tatgaaatag ctaatgattt atattttgct atatttattg 93060 taataatcaa tttaataatt ccattaatta aaattgaatt acaattagta gaaataataa 93120 ttcaaactgg tggagaatat aaagatatag acatgaaaaa gaatatagtt agacagaatt 93180 taaaaatagt taatttaaat gataacaata caaaattttc attagatgat tttcttgaaa 93240 ataaatttaa taataatgaa gaatcaataa atactttctt agatgaaatg attgaaaaaa 93300 tatattctga aagaataaat ataaaattgt attgttatca tatattaatg ggattattaa 93360 ctatatactt tttattatct cagatttaaa tatatattat aaaaatgagt aatattaatt 93420 aatattactc aaaaaaaaaa ataaaggagt tttatcatgg aaaataatta ttatgcagtt 93480 gcacagttcc agaatcaaag agagttcaaa ggaagagagt atatttataa agtaccagaa 93540 tattattag aaaaagagaa ttcttatttc agtaaatacg cattggtttc taatttaaat 93600 ttaaatgaag ttaatttaaa tgatactgga gttcataacg atgatttaga aaaatttgca 93660 agttcagtta aagttgttaa agtattaaaa attatggatg aagaagaatt tatacaatca 93720 gaatatgtaa actctgtaaa agatttagat caaagaatta atcaagaagg agaaactttt 93780 gaatataaaa atatcgtatc gttctttgat aatgaattaa taacacacat tgattttatt 93840 tctaaagata acaaaaaaga aaaattagaa aaattaatga gaatcagaat ggagaaatta 93900 aataaagaaa agaacttaca agaaagaata attcaatatc aagataatga attagacgaa 93960 ttatttaaaa aatataaaga attataaata taatatccca atgagatgaa ttattctcat 94020 tgggattatt ttaattaaat taatgggagt tgaaatggat atgtttgaga caatattttt 94080 attttcttta ttattgattg cttttataat aggctttatt ggaaagaaaa aagagtcaat 94140 agcaatgtta ttattagcta tgataatcgc aattggagaa gtcatattaa caatcatatt 94200 tttatcaata taataaatag ggagctgaaa cggatatgtt aaaaaataaa gaatttgaaa 94260 ttaaccaaga tattattaat aatgaattac taaaaacaaa atacttagaa atggagatta 94320 caaaaatgtt taaaaatgac ttattattaa atttaagata tctaaaagat aatctattat 94380 catcatggtt atttgatatg agtgtagcac attttactaa tttagaggtt ttctatgatc 94440 ctgactataa aattaaaatg acttttatag tagatgataa aaatatcgaa tatactttaa 94500 atgaagcagt tcaagaaatg atttataatt tcatgattaa aaaatcaaat gatgaaagag 94560 catgtgagat tattaaatct attattgaat ttgaatattt taaaaagatg aataaaaagg 94620 gtcatgatat tgatatggag tatgctaatt tacttatgga taaagttaaa gaattacaag 94680 ataaatacaa tattagtaat aaacaagcta agaaattata tattgcttat taaaggagat 94740 agttatatct ggaagaaaag agaagtgata aattatgaaa aataataaac cgagtttaat 94800 tacatggtta ttatattatt gtgacaatga ttcaattaat aacgctatta attctatatg 94860 tatatttatt atctctacat taattatatc ttatacaatt ttaattagta tgttttcaaa 94920 tttttcatta atgtcaaaat taataatatt tttaattgtg gttttgatat ctatatttgt 94980 tatcaaaata aaatatgatt attttaattt tagagacata tatgagtaca cagacttaaa 95040 tcaatgtttt aagattgaag gagaatacta ttcaaaatgg tatattaatt tatgtaatat 95100 aaaaaattat acaatgttca taccaagacg ttctaagggt agaaatcatt ggattaattc 95160 tatagagtct aatcgtcttt taacatatag agaattctta agatataaaa agaatagact 95220 taagatagaa aaagcaaatc agaatattga agaaataaat gaatttcaga agtatatgga 95280 aataaaaaat aagaaaagag aggggaacat atgaaaaata gagtaagtat atttgactgg 95340 tatctttata aaacaggtta tgatacaatg atacctttta taattaaaat aataatgatt 95400 ctcggatcaa tattattatt cttttcatta ctaggagtta gctataaatt agcattatta 95460 tctttatttg tattagttcc aataataatt tcttctataa ttataggtga aaaatatttt 95520 aattcaagaa taatggaaga gtatcaacat ttaaataaat catataagta taaaggaaaa 95580 tattattctg catggtatat aatattaaat agtaaagatc catacttcaa agagttaatg 95640 gatattatgg gaaatgacgg cactcttagt gaagaccgta atatacttta taatctagac 95700 ggactatata tgcctccatt taaaaaagga gttatagaaa gtcatgaaag gaaatataaa 95760 aatcactgga aaaataatat tgagagtaat cgtcttttga catatatcga attcttaaga 95820 tataaagaga ataaactcaa gatagaaaaa tcaaatgaaa tgattaaaga aataaaagaa 95880 tttcaagatt actataattt aaacaataaa ggagaaaata aaaatgaaca ctaaaataat 95940 cgcagcattt ccaggtacag gtaaatctta tattaaaaac aatatcacat tcttaaaaac 96000 atctgattca gattcaacta gcttttcatg gttagtaaaa gatggggaaa agattagaga 96060 tcctagattt ccaaagaatt atattcgtta tattaaagac ctttattata agaatgtgat 96120 ggattacatt tttgtatcta cacacaaaga ggttatccaa gagttgattg ataataattt 96180 agaatttgtt gtagcttatc ctaaacgttc agataaagaa atttatctaa atagatataa 96240 agaaagaggt tcagatagta aatttattga gcttcttgat aatatgtttg atagttttat 96300 agatgatata gagaatagag ttcctgaaga aaacagaatt gaacttaatc ataatgaata 96360 tttagctaac gtattagata aaatttaaat aaggagaaat taaaaatgag atactttaaa 96420 ggtatagtag caggaaaaga ctttttctta aaagcagata atgaagaaaa tgccattaag 96480 gaattagcat caaaagaaat taattctata ggatctttta caatgttaag taatgaaaaa 96540 cagaaatacc taataatttt ctttaatgaa gatgaagata aatttgttgt tggaaatgga 96600 ttagaatcat atatatcatt agacagtctt aaatctgaat tagaatctaa agatttagaa 96660 tgttattatt tagatttagg taatacagat aatatcgaga taaacggtat tataaaaaat 96720 caagaataca cattaacaga aataataatg gaaagtatta aattaactat gaatgatttt 96780 tatcaacaag ttataaattc tgtattaact gaattaactg aaaaagaata caaaaattca 96840 atagttgtta aaaattttaa ataactagga aggaataaaa atagtgagaa ataaaaaaag 96900 aagcatagat agtttgataa ataataatct agaattacca attgagatta ctgaaaatta 96960 tataaataat tttatataca aatcattaac tgctataaat aagaaaaaag aaataaaacc 97020 aaatcaaact tatataatta atcataagaa tgaattattt aataaagcag ataatttcat 97080 aaattgtatt ttagaattat taaaaggtga tgtgggtact ttaatagata aaaaagattt 97140 aaagttaaaa agaaatgtaa agaaagacaa tataagtaat tgtcttacaa tatatactat 97200 tgtagaaact ttaacttaca ataattctat aacaatgatg atggtaaaaa atgtaaataa 97260 taccaataag gaagtaactg gtgaactaat atttgatatt aatataagtg ataaattagg 97320 taaagataat tacaatgaaa atatttatat ttaattacta tttaaatata tattatataa 97380 atgaagttaa ttaaaataca ggagatgaat tggatatgtt aaacgatact aaaaaagttt 97440 tagacagaat atatgacaaa ataaatggtg atttaattgt tatttcagag tgtaaagatc 97500 tatttgataa ggaattaaat tacactttaa ctgaaggtaa tgaagaaaca acaaatcttg 97560 attatttggc agattcttta attgtagttt cttcagatat atttacttta aatgaagtac 97620 ttaatattga tgaagaaact attaataaag aattattaga agaatttaaa ttgagttata 97680 gaatgataca aaatttccat atgaaattag aattaagtag ttataaatta aaaaagatta 97740 aaacctcggt tgaataaata taggagatga ttaggaatga attatttaaa gaatgaaaaa 97800 gaggaggtct ttccagtcaa tgaagaagga atggagaata ttatattctt tcttctagac 97860 tactcacaga aaaatgatta taatacaatg aatataatta aagaaataaa tgatcacgtg 97920 atgaaaggcg aaaatataag taataaattt attaatgaaa gtacaaaaga agtgatatta 97980 acattaggta aagtaaaagg taatttaact aatgaattag ctagaagcgg atatatagtt 98040 aatttctcta gaaataaaat atcattatcg atatatgtaa aaaataataa tttcaaatta 98100 gtaagaattt cagatcataa tattaataaa aaagtaaata agaaaggagt aattagtaat 98160 aggtttgact atcaagttaa agctgacaat aaattggtaa gtaataaatc tttaaagaaa 98220 tatggtattg atgtatcaga aggaatttat tatttagatt aataagagta ttgaattaga 98280 aatcaattat atattataat aatgaagata aatattatta atattatctt caataaaaaa 98340 aaaaggagtt ttatattatg acaaaattaa atgaagaagt attaagagat tttcaagtaa 98400 gaactgagat tgatggagaa tttgaagtca tggagtctga tgagcttggt gttgatgaag 98460 cttatgataa tgaactaatt aaagaattag gattggatga agattcaagc gtgttttctt 98520 atgcaatagc agaaaaaaat gatgaagaaa atatgtatac tttagaatat agtcatgaag 98580 gagttctact aactattcat gattatgatg aggaatatgt tcctcaagct atttataaaa 98640 atgtaattta atgatttaag tatagctgat atctttaacg gatatcagct atattatttt 98700 aattttttta cttgaaggag atgaaaagga taatatgaat tattttgaat tggaatttac 98760 aggtttaatt gataacaatc aattagataa tggagtttta cacaaacaag aaaatgaaga 98820 aattgaatcc ggtcttttaa atatgattct atttaaattg tatctaaaag aattctataa 98880 tgataatatg gatgatagtg atttatgtaa aaaactaaaa atagaaataa gaagtgttca 98940 tagctatagt gattcagaaa tttatattaa tgaggacttt gctgaaatat atgatggtat 99000 taatccgaat aataacgtta aatcaagaaa aataaataaa aattatgaat atttatttaa 99060 atttattaag gataatataa atgagaaaga tttaagtaat atacacgtaa ttaaatttac 99120 aacatttgaa atagaacggt ataagtctgt tgtacgttct atatactcag ctaaacttaa 99180 aattaaaact agtaaattca ttagtcgtta tagaacaaca aaagagttag tattctatga 99240 tatttcaagc gaaagtttat atagattgtt gaaaaataca aatagaataa gaaatataac 99300 ggaaaaggaa tataaaaaag aattagttaa aaggagtttc ttataatgta tgaagttaat 99360 aaaaaattta aatatgctaa aagagataaa gaattcacat tatttcacca taaatcaaaa 99420 gaagaaataa ctgattcatt tataattaat aattatattt catatgtatt atatcaatgc 99480 tacgaaagaa caccaggaaa tgcagaagtt tggttggaaa ttaatgacat aaataatata 99540 aaaggtgatt tcttatttaa atttatgttt gacaacagac cttcttttgg ttctaattat 99600 tttcctaagt gtaaattaaa tatacaagat aacagtgata ataatattgt aactattgaa 99660 tttagtgata aatataaaag acataatttt attctagaag aaatatctaa atttaataat 99720 gttcatatta atttttatga agaagtatta tttaactaatg aagatgaaga attcaagtta 99780 ttaaagaatg tatttaaaac tgataacatt aaatattacc aaaataaaga tttaattagt 99840 tatatttcag acaaagaagc tagaaaaatt ttagtaaaag aaaactttaa atagaatagg 99900 ggcaaataaa ttgaataaat attttaaatt taaattaaat aataaaagtg attacgatgt 99960 atttaaattt tcaggaaatg aagaagaaat aagcgattct aaaattatag aatcttattt 100020 tgcttatatg tttgattatt atataagtga agcaatacct gatactagca tgataaatat 100080 tacggtattt actaaagatg aaagaaaaag attatttaga ttttctatag ataaacctcc 100140 agtttatata gaagagcctt ttagtacttt atttatgatt gaaaatgatg aagataaaca 100200 agtcaatttt agagatttta atgaaattaa aaagtttata cttcaaaaga ttatggaatt 100260 aaatgaagac gaattttata tttacattga ttataacttt gatttttctt ataaaataga 100320 ttacgatgat gtatttgata aaatattatt tactaaaaat aatctaaatc tttatttatt 100380 ctttattaaa gaaacagatg aaaatgaata taaaaattat ctagtaagag agaattttaa 100440 ataagaaagt gagatagata aatggaatat attatgatga atgaattatt aacaaaaaat 100500 gattcatctg aattaaaact aaatatggtt aaaccatata aagaagaaga ctttttcaat 100560 ttctttttaa actttattat agaatataat tcatatcata taggaaatta taaatacttt 100620 tatagtataa actcattatc ggattataat tcagattatc aaataaatgg aaatccttat 100680 gtgccatttg aggaaggaat aaaagtaaat gaagtcattc atatttataa aaataaatta 100740 tttagaaata taagtaaaga cattgaaaat agaataacct tactttatgt agaagacaaa 100800 gaagatgata tttcctatta tatattaata tctaattact ttaataggaa atttaaaaaa 100860 gaatataaag aagaacttcc cgaaaaagaa aaagtattat ctagacttat agtaggatct 100920 tttctaaatg aaaagatttt attagattca cattcagaat ttttagttat taaagataaa 100980 gaaaaattaa gcaatttaat tactaattta ataaaaaatc aaaaatacaa aattttaaac 101040 tttgatttct taagcaatag tgaattaaaa tataatagga tactatttaa taaaaatgta 101100 tatgataata aattagtctt gaaatattta aaaggaataa gttacaaaga cattattgat 101160 aaagataaag aaaaaattac gtttataaat gaaaaagaat ataaaaaact agcagtgaaa 101220 gaatcattta aataaataat aaataatctc atccattcat tataataataa cttttaatta 101280 tataataatt tttagaatgg atgagatgct tttatgagta attatttata tcgttttaac 101340 aaagagaatg taaatatctt ctatcataaa aggactaata atggtcataa aatgttattt 101400 aataatagta atgataaaga tagatctata tacttaataa atactgatga agaaatcaat 101460 aatatggaac tagtatctaa atatattgct ggaaaagtat ttgaaatact aaatcaagaa 101520 aatatgaaaa tagtacatat ggatttcttt aatagtaaat tagaattctt tataagtaga 101580 tcatccaaga ataaatatat aatgaatatg tattttagtt taaaaagtta taatgatcta 101640 attgaaaatg aaaaagaatt tatagatagt gttaatgaac ttaatttaga ctttttaaaa 101700 tcagtttctt tagatcaaga caataatcat gtattagata tgacattaat atttttaata 101760 gataaaaata agatagatga atttattaaa aatctatttt acattaatta tataaagata 101820 atagaattta taatagatac tatatctgta tatgcagatg attataagaa atttaatgaa 101880 gaaataaata ttcttttgga tcatagaaat tttatagaag agataacata taaagaatat 101940 aaaaagataa tgacaaaaga gatgtttatt taaggagaaa ttaactatga aggtttcagc 102000 caataaagaa ttattaggaa ataaagttat acctttaggg tttaaacaac ttaatgactt 102060 gtataaagat catgattatg tatatttaag aattcctgaa atatttaatg tatttgataa 102120 gtatcaattt aaagatgata aatttgtata tattaaaaca gaaataaaaa ccagtactat 102180 tgtagattta atagattctt tatcaggtgg tcataattgg ttagtaaatg aatatatttc 102240 taatgatata ctaaatatac attataaaaa gaaaaattta tagatattt ctaacagtga 102300 atataaaagt ctagaggaaa caagatctca actagattta gaattggaat tcataagtag 102360 taatgaaaaa caaagaaagc aatctaatat tttaataaag gatattcata aagaaataaa 102420 ttatataagg aatgaataca caaaagtatt cactcttaag aaaagtaaaa ccagaaataa 102480 taaaccaata aaaataaaaa ttagaaattt atatgatgaa gatccaatat ctatattaaa 102540 aataatatta gacttaggag aagaatattg tatgaatagt actatattta acgcattcac 102600 ttattcatta atgttaacaa ataatttaga tttcatagac gaaaaagaat ttcaggatat 102660 agttaagaaa gagaaagtga aaaatacttt catttaaaac attattcata tagtttgagg 102720 aaattttcct taagctatat gaattatttt attttttttc taaaaatata aactaattta 102780 tattaataat ttttataatg tatcattcac ttagtcgcaa atatttattt attttaagaa 102840 cataaatttt atatcaaata atatagaatt tttaaaaagg agaatttaat tttatggaaa 102900 aatatgataa attaactgaa gaattagaag ctttatatga gcaatctcaa gaagaagctc 102960 tagaagaaca attcgaaagc attattgaat cagctgatga agataaagca gaagatgaag 103020 ttaaagataa agattctaaa gaggattcag acgaagaaga aacatctgtt gaagaacaat 103080 ttaacagtat cttagaatca gaagatgaag aatcagaaga tgaagaatct gacgaggaag 103140 atgaagaaga ttcagttgaa gaatccgaag acgaagaaga tgatgaagat tcagttgaag 103200 aatctgatga cgaagacgaa gaagatgatg aagattcttt agaagaagaa ttaaatcgtt 103260 tatttgaaga aaatgaagat ccagaaatgg atgttgaaaa gcaaactaca aaagctaaca 103320 acatgaactc aaaaaaatca tctgattcta ctgaacatcc tgaagaagat gtaagcaaaa 103380 tcacttcaga agatgaagac gaagaagaag atgacgaaga tgaatcatta gaagaatcat 103440 tagatcgtat ctttggttaa ttattaatta atctttaaaa tatcccctaa ccttattaat 103500 ttaaggttag gggattaata ctgcattttt ttatctaaaa tagtttgtat tatcagtcat 103560 ttttcttcca aaagcatcta atccatctaa tggattagct ttatctccag ttgctttaaa 103620 atcatctcca ccgtaagttc cactaaaatt agtgtctaca ccttttgata attcttcgct 103680 catcatattc atgtgtctaa ctctttcttt ctttctttgt aaatatgctt ctgcttcttc 103740 aactgacatt aatctactct catcaatagt ttcattttct tttaatttaa ccactggttt 103800 aaaaccttcc atgtatacat aaaacttatc aatttgatct tgataaatga aaggaatttt 103860 agtttttaaa tgaagagttg taggttcatc ttcatattgt agagtttcat aatcaagtat 103920 atttccttct ttatctactg ttactgctaa gtccatcata atttttttt catttttttc 103980 ttctgacaaa atattcaagt cctttccaat taaatattag tttctaccat aaatatatga 104040 gttaagaatc caagcattac ctttttgtcc tggtttaact cttgcacgaa ttgctataga 104100 tgctatagat tgtgccggaa tacccatatc tacaataatc tctttatgtt ttgtcttagt 104160 tacactagtt gatgtgtctt taggtataga tacagtttta tcaaagaata ctccattttg 104220 atcattaaat gaatcaactt taatatctat accacattgt ggagtagcat accatatacc 104280 aatgtgtaac catctagttt catgttgtcc gtataatgtc atagcacgtc taaagtagct 104340 accagtagtc ttatcactaa acataaatgc attaccaaca tttttaaatc ttggagtacc 104400 atttgacatc aaatcttgta cacctggttc tgaacgtaca taagctgtag taaatcgagg 104460 cataccgtta taaactagat atccaccatc aggacgttta atagtaatac cacccttaac 104520 ttctcccata gcatctaaca ttgtttgaac aacaatattt ttagacatta aattagtaat 104580 agccgcttct ttaatagtag ctttaccatt agaaattatt acatcaccat cattgatatc 104640 aaccattttg gattttaatt taatattatt aggatcaact tccaatgtag ataatttatc 104700 attagaagaa gatgacatag taataccatc tgctaaaata gataatgcgg aacccatttt 104760 ttctatttta gttttatcag cattgtaaga ttctttagta acacttaaag cgatattatt 104820 ttctgtttga ctaattctac tttccatatt agtaattcta gcattactat ctttaataga 104880 aggttgccaa gcagtagact tgttaccttc ttcaactttc aatccttcaa tatcaacaga 104940 cattgggaaa gttccatttt tattaataac catattaatt aatgtatcaa ctgtaaatga 105000 atcattagga ataaatacta cttctattaa cgttaaagca gaagtatcat caaacgtaat 105060 attacgtgaa tcttgacctt tagcaacact attaacaaaa gtattagtta tagttgaatt 105120 aggtatacta atatctacat tagttaatgt accagttttc ttttctaagt taaaacttaa 105180 tatgtgttca cgtctatttc taactttatc taatttaaat ttaatacctt gaccgttagc 105240 agttaaagcc gcattaagtt ctccgtattc taaataacta gttttagtta aagttacaga 105300 accaattggt gtaatattat caatactaac taagttcata ccgccaactg taattttacc 105360 agcttctgta acagcataac cattagaaat actgtcaata gctttttgaa tagcatcttt 105420 aatatttgat tgagcttcat tatatctcaa gtagttagtg ttaaattgag ctatttcttc 105480 ttgagtagct actccatcgc taatagtgtt agtaatatct tgtattaata tattatattt 105540 ttcattaaat aaatcatatt tattttttaa atctgttttt actgaattag ccatcatttt 105600 attaggataa agtgtattaa agattttatc tatctcagct ttatccttat caataacatt 105660 tttttgttta tcaatagcaa ttctttcagc attagatata atgccatctt taaaagcctc 105720 agtaaccgta tcacctaaac ctacagcgtt cttttcaata ttagttattt taccattaat 105780 agttttatta tagttttcta acatattgtc ataatcttca ggagctgctg tccagtcaga 105840 agaaacacta cctctttcaa ctttaactct agcaatatca aatgtaccac ttaaaccatt 105900 aagatcagtg tctactccaa gaagtaattt agtattattt cttccagtca gtgtttgttt 105960 atatacaaat gaatatctat gccattcttc atcaatatct aaatactttt cagcaattgg 106020 tgtagaataa ttaccagaag gatcaataaa gtaacaataa tcaagtctat taaatgtatc 106080 tgatctaaaa tcaaatgaaa tagtataagt ttcattgtat tctaatttaa atccattata 106140 gctttgagct cctacttgac cttcaattcc ttcagtatta attgtaaaat aacttttacc 106200 gttactgtct tgtccaaaag ttaaagcatt tgggtttgat gaatttaaag tatctggttt 106260 taataaccaa ttacctgaaa ctgctaaaga attttctaat aagtttttac caccaataac 106320 aataccatcc atttcagatt tagaaactgt ttgttctatt aaatctgcaa attgagatat 106380 ttgactttca aattcagtta ctttattatt aacggtatct atatcagctc tagtgactgt 106440 atcttgtaaa actctagctg tttgttctct aaatgattct aatttagtaa tactatcatt 106500 aatttcatta agagtataat cagtagctat actcttaata gattctgcag tttgttctac 106560 tttagtactt aaatattgta tagatgattc atatttatta actttagaca ttgctattga 106620 taaagattct tcattagatg aaactcttcc atttaaagaa tctagattac ctttaatatc 106680 agaatcccat ccaccttcag caatactatc aatatagtca atacttagtt tttggtattt 106740 tcttaactcc gtttttaatg tatcaagtgt aacatagtta gataaatcta aatcaatatc 106800 gtgactacca tctaaatttc ttaatttttc tactaaatta tcattttctt tatctaaaga 106860 atcaatattt gtatttaata cattaattct atttttatta tcttctgata gatttttaat 106920 gctatcttgt tcttgtaata aagaattgaa tttcgattta atagaattta tttcttcatt 106980 tatttgaaga agattctttt ctttatcttc cattattaaa tttcaccaaa ctttcatttt 107040 tattaaaata ataagttgat gttttatgat tttaattaaa cgaataatga aagattgatt 107100 gcatttgtat acggatctga taatttatat acataaatat tagtaatcat taaatctttc 107160 atctcaattt tattattttt cattaattca tctaactctg tatcttcttt aatagaatca 107220 aaaatagctg gaccaatata ttttaatact tctttgtcta atttatcagc cacatcttct 107280 tcatattctc ttaaatagat ttcgtaatca tcattacttc cctgaaaact ttgtttattt 107340 ttagcatgca aatcttcatc atctaatttg ataacaaatg ttggtttttt aacatcaatg 107400 tgtttttctg ccgcttcaga tctaaattta aagttttcag atttattaat agtatcacga 107460 ataatatcaa ctgtattctc taaatcgata tagttcataa tgttatttct aattctcatt 107520 attaactgca aatctctaat atctttttct tcattaacta atacatcttt attatttctc 107580 attgttattt attctccatt cttttctctt ttattttttc tattaatgtt ttatatctat 107640 ctaataatac tttatccatt ctacctttag attcttctag atcatctttt acatatttaa 107700 tatgtatgaa tgttttatct ttaaaatcac tagaatactt cttaagagaa gttactttaa 107760 atatctgagc atcatctttc caaaacattt cattcataac atcaaatgta gttttttgga 107820 aattatcaac atcaggagta tttgttctct taattaaacc taaaagttta aataatataa 107880 gttttattga atcagtatta ttacaaggat ttctttctgt aattaattca aattcaatag 107940 gactttcaaa attattttta atgatatctt ttataaaatc ttcttttaat tcttctttca 108000 ttcttttctt taattctttt ttatatgtgt gtaaaggatc ataagttctc attccgcttt 108060 ttctatgtct aagatattga taaacttcat gatcatctat agaaatgata atttcattat 108120 catttacact tttatactca atgttacaat ttttaacttc ttcaatttta tctaatatct 108180 ttttaggtac ttcttttttc tttttaggca ttttcattca attcctttag caaagtgtat 108240 atttataata ataacgttat atgtatatta aaatttttta taaaataaac ggtaacattc 108300 aatttaatga atgttaccgt aaagtatatt aatttgattg atctccagca gatcctccac 108360 ctaagatttc aggattataa ttagcatcag ctataacatc tgattctatt aattcttcgt 108420 cttcagtagg aacttgttgt tctaaatttt cactctcagg aatttctgga acctttgaca 108480 agtttgtagt ttcttggttg ttctcttgct ccaaaaaagg cttcactgga ggaagaaccg 108540 taccgtcata gtccattgct tgaagagatt tttcattatt tgtagtaggt ctacttttaa 108600 ctaagttacg ttcagagtcg gctattcctt cagtagtact atctacaaaa cgaccaacta 108660 aactagatat aacacctgct aaaacttgaa ctatacttaa aacattagtt tcagtgtcac 108720 cagaaacttc tccaccgaaa gcacgaatta agaaaataac tacgttgact aattgaatta 108780 ataaagctgc cgtccatgct ttatttttaa atctaactaa tacgttaatg tgtttatctg 108840 caccaatttt taaatttttt gccaatttaa tatttctcct ttttattaaa ataaatattt 108900 aaaactatcc tccaaatatt cttctaagta tatctaagat tactgaagga gctagtatca 108960 aagacactat attgataaat aaatttcttt taaaagtttt actttccttt tcatcactat 109020 tagaaccgtc ttcaatcttt ttaaactcaa tttcaaagtc ttctatatta agtttactat 109080 ctaaacccaa tcttaaatct tgtatatcgc tagttatctt tctttcaact tgttcaacat 109140 tttgatttaa ttcttgttta acagatgta tttgtgattc taattcataa tgtcttcttt 109200 ttctttcttc ttcttcaatt tttctatttt ctctatcttc tttcatttct tttctaattt 109260 cttcagtatt tttacccatg ctttcaagta atacttctac acgtactaag gtgttacttg 109320 ttttttgact ctcagattta acttcatcta ttttcttatc aaacttctct tcaatttctt 109380 ctttaagtga attatttgac tttagtaatt ctaattcagt tatagattta ctattttcat 109440 acaatcttct tttatcttct tccatttata atagattcca ttctcatttc aagaattgta 109500 aatactgcaa agaagagatt taggaaagag atgaaaattt ttaatattat ggtagattgc 109560 ataccagcac tatctaaaga taaaatagcg tatattaaaa atagagcgaa gttaataaat 109620 gcacctatag tcattaaagg tttcgtcatg aaattatcta agaataggga agcggctaaa 109680 gccaatcctc caataattaa aaatactcca tatgttttta aatccataaa atgagaaata 109740 gccacataaa tatctgatgt tctataagct tctcttgttc gaaaaacaaa ttgaaaacca 109800 tagattaaag aataaacagc taagaaaata ggagttatat aatatttaaa ttgcttaaga 109860 aaataatata atttgatgac taaactattt gcttcttcaa cacttagatt atcttctcta 109920 tcattatttt tattatcgtc cgtcatagtt atttttcaca tcctattctt ttattataaa 109980 tctttattat aaatctttgt tcttttaata gacttgatgc gtcctataaa ttttggagca 110040 aaataaagtc cctaacactc aaataagaat gttagggact gtttgaagac tttgccaaaa 110100 ttaaaagaaa aaagaataaa gatagacaag aacaaagaaa ttgtatgaaa gatatttatg 110160 taaataactt tcatataaat atgttctatt ttctttattc aattgacgtt gataagaatt 110220 actgactagg taaagatccg ccttgagcag ttgaaggatt ttcaggatct tcttcttgag 110280 gttctacttc tgtagctcga ccaatacctt ggacttcaga atcttccaca gcttcatcaa 110340 ccatatgttc ttcttcaata ggatcgattt cttcaaccac ttcgtcatca ttatcaatga 110400 tacttgaagt agtatactga ggactttctt gttcttcagt tgtattgtcg tttaattcat 110460 ctaagatttc tccgactaat aatcttaaat tattaccttc ggaaacttct tctaattcta 110520 ttacaccttt agcaactaaa gttgcatgaa aagttacaat aaaagatttt ttatcaattt 110580 tcataattta aatttcctcc tattttttat tagccaataa agcagctaat ctctcttgaa 110640 gctcacgaat ttctttttct tcaggagttt ctactggttc ttctttctta ttgaaagttt 110700 gaccaggttt ttcggctaat ctaggtgtag cattttcata ttcgattttt aatttttcca 110760 tctgttcacg aatattatgg tctacaataa atattaaagt ttcttgagtt gaatcgttca 110820 tattacctat agaataacct gaaaagtttc cttcttcatc tatatcttgc atattgataa 110880 tcaaccaaaa taatccgtca attcttcttc ctctatcatc atacatactt ttatatgttt 110940 ctacaagtgc cattataaat cctcctataa attatatttg ataattcata gtttattttt 111000 ctattacgta atcgccacct tcaaaatcac ttaaagacat acgaagtatt tgaagctggc 111060 catagttaaa ccctccagaa gttcctgtta ttgctagctg tattacaaat gttttactat 111120 aattatcagg tttccctaaa tctatggtag ctatctgtat ttttagaggt tctccacctt 111180 taactgctat ctctttaaac ataggaattg atgagttagt cttccaacct tctttttctg 111240 caaaagttat ataaagatta ttaccttctg tggctcttcc caggtaaaca aattttaaat 111300 aacgtttatt atgatgataa ctaaatagat taagtgtagc cttgtctttt ccatttgact 111360 ctgctaattg agcattatca taaccgtact tatatacatc tctttttatc atatatgctc 111420 ctgcccatgt atcagtttca actatttcca tatgattttt aacatctgaa gaacctgtaa 111480 catgattcca tgttttaagt ccaggcaaag taggtacaat atttgtttca gattaaaata 111540 gaccatcaac catttgatct acaccatttt ttctaatgtt caaaccagta gaatttattt 111600 caacataatt atcgttatct aaagcagttt ttgatattct taacctatct ccagtaaaat 111660 ttaagttacc tttaactatta tatatagtca tcttatcagt attaaaatca atgcttcttg 111720 atatcatttt aattgattct ggattcatag ttattttact tgataaagaa ctagtactat 111780 acttatctaa tgccgaaggt gtccatggtt ttaattggtt tcctttttct aattttggaa 111840 gagcatagta aaatacagtt ccatcattat atacatcagg tttatcatag ttattgtaac 111900 gtaataaaaa tcttagataa ttagtttgac cattagcgga acttctaggt attttagctg 111960 taaagctata cctagtccat ttatcaaaca caaaatcgct tgctggtatt tcaactacac 112020 caaatttagg attagtagtt tgttgtatat tttcatatgt tgctacttca aaatatattt 112080 tataagtaag agactttcta gcagttgaag gaatgtatat ataaacagaa cctgttactt 112140 catctccaat actaaattgc ccttcttgtc ccactggtaa ataacttgaa attactgcag 112200 gccaagttgt tccgaatgta ttctgtttgt atttaaatac atttcttact tcattgatgt 112260 tgtatgacat atcactgtcg ttagagacat ctttagattc cttgacaact atattttcaa 112320 aagaaacagt tatatcagag ttatcagtgg accctgcttt tgcagcataa aataataatt 112380 gatttatttt atcctcatta ggagtggtaa tctctattat atttctttta tttgcactga 112440 caggatagtc taatctatta accgaattaa tttcaggaag tgtatctgca tcggttgagt 112500 accctgaacc tttataagga tatctatatg gatataatga aattaatcca tcgctattct 112560 tcccagattg tatattataa tcaaatgcaa ctttatattt agtattcttt tttagataac 112620 catttaacgg aagagtcatt cttttataag gtcctctaga tacgttgttt acacgataaa 112680 ctgatcctaa agctaagtta tcatctgtat taattgtcat gtcttcttca gaagatattg 112740 agaatctagg gtttttagga taagttccct catcaagtct tatatttcta aagtaaaact 112800 taccatctga gtaaggagaa acggaagcta tgatcaatct tatttgtttc atatcactta 112860 aatctgagct agttaaagta aaattagttt ggaaagtggt ccaatcatca ttaatatcat 112920 tctcagcaga tattgtataa cttaatgggt taactgtact tgaactattt ttatttacac 112980 gaagacttac agtaatagaa cctttagtgg tttctactgt ttttctaaca tcaaaactaa 113040 aattataagt accgggctta attttagcta attttgagct tccatctgcc ccattataat 113100 caatattgga tgtctgccat tgcttccaac cttcactagc atctgaaatt atagataaat 113160 aatctctata atttgtagta gtgtccgttg gatttttttc agtagatcca ctaaaagtat 113220 aagcccaata aggtgaatca atcttatctg cgaaatttaa attctctgat gtttgatcat 113280 cattagttgt ccatccttcc catccattcc taagatcaga gttaataagt gagttatctg 113340 cattaagata tttacttatt ttattaacag atagttcaat agaatctgct ttttgatcta 113400 ttttagaaga aacagtagat attgaagtct caatatcttc aggtgctgga gaccaatcag 113460 tagatttatt acctttttct actttgatcc actctatact tgataaataa tttccatctt 113520 taggcatatc gtatactgtt aataatcttt ttaaatttct ggaagattct tttgctgttc 113580 cagttcctat ccaaagatct tttttagcat catatgttaa agtacataga tttgtataac 113640 catcatcggt ataagcactg aaataatgat ctttattatt tacattacct tttattgtaa 113700 ctgtataagt ttctccaatc acccaatcca atgacatatc atatggtttt ccatataatg 113760 tatgattggt gtatttatta tttttactat ctagaactaa atttcttcca ccgattctaa 113820 tattatcaat ttgtgaatta acatcttcag gagcaggtgt ccaatcagta gctttattac 113880 ctttttctat tttaatattt tcaatagaga atttatctcc attattatta ttgtaagcat 113940 atatagccca tctagaatta gttccagaag tcttagttat tttagaagta tatttatatc 114000 taaatttttt attaccaaca ttagttattg tatcactacc aatagacatt cctggatcta 114060 ctacactatc atatattcta aaaacatctc cacgttccat ttgtaaatca aatgatatag 114120 aaatttcatc tccgactttc actttattca ttaactcatc aatataaatt ctccataaat 114180 attgataagt accgtttgaa ttatcttcaa aacctttatt ccaagataaa ctgttttcta 114240 ataagtttct agcacctatt tgaatattat taatattttc attaactcta ttttctactg 114300 cagtaacttg tgatgtaatt tgatttggta attgttggat gctagaagta ttagcagaaa 114360 ttttaccatc catctcatct tgtttactaa caatactagt gatcttatca gtttctactt 114420 ttaattcact atactgattt gtagttttag tatctaatgt cgtaatagaa gaagcgttaa 114480 gtgtaatatc tttctcagtc tgagttatac gagtttcatt tttagcaaat ctgcttctat 114540 aatcttctgg tgatacgtcc caagaagaag ccacattacc ttcttctaat tgaatatgac 114600 ctacgtaagt gtctttagtt gtattatttg cagtgaactg aattttaagg aaattatttg 114660 ttttagaatt gaatcttaac tcatatctag taggagttgt tgtcagtgtc ttagcagatt 114720 cagtcatagt aataagataa tctttaggtg aaacttcagt agttaaactt gaagcttttg 114780 taataggtgt tttaattact ggtgaagcgg cagctgaata agcatcataa cttaacacat 114840 aatttgtatt aggtttaact gcaactattt gagacacttc agctaaattc gttttagtat 114900 tagcataagt tataccatta ttgacttttt tagtaatgct agctaagaaa ggtaaatcaa 114960 atttttcagt tccagcaagc atattcttag ttccaatttt aactttacct gaaatagctt 115020 cagtactcgt ttcagaagta actctttgat caattctacc aatttcagct gtaatattag 115080 tattaaatt tgatacagtt tcattaacac tagttttagt agcataatct ttagagatat 115140 cttgtctaat agaatcagct gtagtagtaa tactagcctg taaagtttgt ttagtgtcat 115200 taatagcaga ctgtctatct gtaacttctt gagttatttt atcattagca acttttaatt 115260 caccagttag attactgata ttaccttcat ttttagtaac tttatcagca gtaatagtat 115320 agctatcatt aagttgagtt actttagttg ataaattaga atagttttca tcgcttctat 115380 ctattctaga aactaatgat gtgatattat cagtagctac ttttagacta ccttctagat 115440 tagtaacatt ttcttgagtt actttttgtt cttcagaaat agctttaatt tctccagcaa 115500 ctgtttctaa tctagatgat atatctctaa caactttatc atctaaatct tctatcttct 115560 tagaaacctc ttgacgaatc atatctactg tttgactgac ttcagagaaa ccttcaacta 115620 tctgtttacg ataatcatcc atttcttttt tagtcatcat agtagctact aattcgttag 115680 tatcaattac agttttctta acagattcta gtccagtaac atcatacatt tctaaattag 115740 taacccagaa tttaggctca tctgatccat cttcaaattc agtaacatct gaatcttcag 115800 attggtttac tttaaagtat aatgtcatat agaaagcacc gtataagaaa ccattagtac 115860 ctctaatatt ttctttagta attaaacctt gacggtgata ccaaccatta aattcttcag 115920 gatcgtcatc ttcttctgta ttaggaatat cttcatcttt aattaaagac cattcaacat 115980 tactatcagt gaatgttcct gaaactttag ttccagcagg aaaacctccg tcttcagaat 116040 cataattaat taaatcaaaa ggtctattta aatagataca attattttct ctatcaatag 116100 ctccaaaatc ccaaccgttc atgaatacat ttctagaata agttgattct ccataattat 116160 aaccatcatt actcttgaaa ttccaaataa ctaatgaatg attatcatta taatccacta 116220 aattaggatt aatatttcta ttaactattc ctgcattaga tacattataa ttattagtca 116280 tattcttaat agcttcttct tcatctactg gagttgaatt agtttcaact ggttcgtcag 116340 attcagtcat aggaatatca ggttctgtag ttttatcttc ttcaggagta tcatctgcat 116400 atattactct atcttcttct tcatcaggca atgcattagg atcatctata gaaagaatat 116460 catctgcatc attaggtaat ataaccgatc catctctatc ataatcataa acaggagtat 116520 catcttcttc atctaacggt gcagattgga atctgtaagt atcatcaagg ccatcaaggc 116580 tattgaaata aataacttta tctccttgtc ttaattcttg agctaattca attacaggtt 116640 tttcactacc cattacatgt tgagattcta ttaactgtcc gtctttatca taacttaaat 116700 gacctataga agaaggaaga gaattattat tcttcataaa catagaaagt ttatatgtct 116760 tctctggatt aataggtatt aatctttcag aagaaatagt agagttaaat ccttccattc 116820 taaatgaagc tgctgattgg aaggcatctg aattatcgta atacattcca gggaagtttg 116880 attcatctcc ttgatctgca ttaccattaa aaattaagtt atctccacga gaatccatgt 116940 agtaattaaa ttcttgttgt gatacttcta attcttgacc taaatcttct ctaacactat 117000 tagcttcagc catagcttta tctatatctt tagatttttg atctaactct tcttgttgtt 117060 tttctaactc tgttttagta ttctctaaat taactttgga ttcagcaatt tcatctttag 117120 ttttttgaat ctgttcttga ataaggtcaa acatatcttg tttatctata gtgccatcta 117180 ttaaaccaga ttcagaatta agcggtaaac ctaatacact tgatagattt tcttttaatt 117240 gagttaagtt ttcttttaaa cctctatcgg aatcattaag gtcactttca attctattaa 117300 ctttcactct cattaattct aaagaagttt ttacttcatt gatatcttca tttacattga 117360 tattccctgt taatttttga gttttactat cataagataa acctaaaact cttccaattt 117420 cagaaaatac agtatcttta ataccatgag aatattcatt ttgaagttta ttcatttcta 117480 agttaatagc ttcattagat aattcaataa tacttttagt gctattaact acagaataaa 117540 atcctacaaa tgatttatta atatctttca ttaatgattc attctgatca gctctatta 117600 gtttattgac ttcagatttt attttatcaa agtcattatt aatttcttta attttatctc 117660 taacctgaat tttaattgca tcttctttaa gataagctga atcaaatata gattttaatt 117720 ggttaacaac ttgatctttt tgagatttaa ttaaattaaa atcagaaata atagcatcaa 117780 agttaagttc tttatttgat tgtaatacac ttgatccatc tgtaccacta ttgttattat 117840 tgctaatatc attaatataa tttttaaatg attctaattg tttattaact aaagattcaa 117900 ctaatttaac atcattactt ttagaagttg tactgtcttt aataaagata ttatcattag 117960 catatttagt ataattctct aacatttcag gtttataaac ttcattagaa tctttatact 118020 tagcaaagaa gttaaatttc tctatattgt aatcgaataa acttctctct aatttatata 118080 tttgaaaacc tgctgttaac tcaggtttaa tatttttata attgatgaat atttgacttg 118140 atataaattt attataatga cagttagtcc agtttcttag cactaaacca gtcattttta 118200 aatctatagc attcaaagaa ctgtcattaa ggtatttaga agcaatttct tccatttcat 118260 ctctagtttt tcctttaact tccatagtgt caaatatata attttcatct ttaataaatc 118320 tagcttgatt taatgagtct ttaacagtaa tagattcatt attgtcatta tacatgatta 118380 agccggtttt aatatttgat ttatctacat taaattcaaa accaggaatt ctaccagaaa 118440 cttctttagg attagatttt cttaaatctt tacctttatt aattattaaa gttctttcat 118500 ttgtattaat atcatactta tgtctaatag ataaatcttt ttcaaataaa atatctaata 118560 atttttcaaa tacagattta ttatttttag ataaagtaat ttcttcatca acaaccaaat 118620 cattatattc aatattatat cctgtattca ataatagagt acttaatact gattttaatt 118680 gcccttttaa ttcttcatta gaattcataa agacattatt taaatctttt acataagcag 118740 gaattaatga agattttaaa ccattttctt caatacaaac aaattcagaa tcattcttac 118800 tttcatcttt aataattata tgtgtatttt ctgaaatata gtttttactt ttgaattcaa 118860 tattaatgat ttcagttttc tactaaaat catatactaa tttctcacta gaaattacat 118920 tttcaaaagt ttctgcaact aatttacctt caattctttt acgttcttta tctagaatac 118980 taatcaaatt taattcacca tcctttcatt taattgatat taatgtgttc catgtcaata 119040 attaatagtc ttctaattgt tcagctagag tatcgataat agtagctttt ttccctgata 119100 gttgaatttc catattatca ataatattta ataaaataga tttatctcta acagtaataa 119160 ctgctttttc ttcatcaata gccaatatat cttctttagc atttgggaat tcacttacat 119220 taagaataat actttctgga tctttagggt ctttaataat attaccattt tcatcttttt 119280 tagaaaattc atcaatcata tcttttctat ctttagcgta ttcttcataa gattctttaa 119340 gttgattaat gaatttagtt ctatgtctag atttattacc attaagtgga atattgaata 119400 acacatcata tacagtttgt aaatcttcat ttttaattgt aacttgttca attgtttcta 119460 ccatttttag aaaactcctt ttaaattgat atttataata taaattaagt tattatggca 119520 ttttaaaaaa ttactcaaca ttttatttat tatgaaacta atagaaagtg ggtagaaata 119580 tatgcctcat ttaggaaaag aaaatggtta ttccatgtgt actgcatcgc cttcattatc 119640 cagtgttata tcaggagtac aatcattcat gtggaactat tttaaatcaa tgttccctag 119700 taattttttt gcttcaactt atgtaaatac ttctcttaat tcaaattcat taaaagatat 119760 gaaggaacgt aaaaaagggt ttcctcattt atcaatgaat actcaatttg aattgggtga 119820 cggttttatg tcaggtttac ctatgtggca taagactgat agatttgtaa tgaaaaatct 119880 taaaagaaat tatagattaa tatttgaaga tgatacaaga ggaatcagaa tatatacagt 119940 tcctcaaaga tataagatag tatttaatta cggtatatta ttacaaacag aaatgggagc 120000 ttggaacgtt cttaatcaca ttaatcaaac atttgaaaat ggtggttata attatgctaa 120060 tgaaataaga ataccaacaa aattaccaga aatatttatt gttaatatat gtagaaaatt 120120 aggtttagat attaataaca ataaagatag aatgcaatta aatgattata tgatgacaaa 120180 cggtttaggt ccaattacta ataaaaaaga tttatctaca ggtaaagaaa aatacactta 120240 tgattatact actaatatat tattaaacta tcctgattta actaattacg aaaaagaagt 120300 aactaattta ataaataaat cagcttcagt tagatatgcg atatctgctg aattatgggt 120360 acctggtagt tatatattag aaattgaaga tgatttcaat attcaaagag aaattgattc 120420 actttcagat gatgttttac aattcgacat tgctatttta caagatatga ttcctaagga 120480 aaatgaaaga ggaatgaaat tattattaga aagaaacttt aatactgaaa tgaatgttaa 120540 atttgattca actcagattg aagaaatatt agataaagat gttataaatt caattaaaga 120600 acttaataag attaatgggg atattcaaaa aattgtagag ttcaaattat ttaagaataa 120660 taaacctatg agtaaagatg aatatttcgt tgattatgat acgtttgaat taattgtaaa 120720 agaacctgaa gataataagg ttcacacact tgtaatgtat gcggatacac gtaagattaa 120780 tatgataaat gaattaataa atcaaggaag aaaaaaagat ttatacaaaa tggacatatt 120840 ttagaaaaaa aaatcaaaat attagaggta actatcaaat taatgatagt tacctcaatt 120900 ttattatttt acattagttc tgtattcaag aatagttttt actaaaagca tattagcatt 120960 taattcttta gaagttcctt cagcttcttc agctttaagt ttacctactt gctctaaaga 121020 catcatttcc attggattaa tatttttagg aattttacct gaattaagtt taataacttc 121080 actagcttgc atagctttaa tagattcatt taaaaattca ttaatgactg aatctgaaaa 121140 gcttttaata actttgttat cttctttttt agtgatatca ttacctttaa ttaagtctgc 121200 tctgttataa tatacaaata aatcaatata agttactaag attatattgt atatttcttg 121260 gaaatttaaa ttagtgccca tattttcatc agtgtaattc aacattaatg caaatactct 121320 ttcactaata ttactttgtc cttctggaag aaattcatca aaatctacac ttctagacat 121380 tgataagaag tccataatat ttcttgcaaa gttttcttca ctgtttaatt cattttcatc 121440 agtaaagaat ttaataaaat cagaatatga taaaccagta atatcatctg attttcttct 121500 aatcattttc atactataaa actctctgaa tgttttacta tctccagttg aacctaatcg 121560 atcttctaag atttctaatt cttttctatt agattcttct ttcatctctt tcattaatac 121620 atttgaaaca tcctcgttaa ttctttctaa gtcattgtta aataattcaa ttgcttggtt 121680 taattcttcc attatccatt tcatctccat ttataaaaat tatttaagat tatttaatta 121740 ccattaatct catttatata atatatattt aaataatgtt tataatttta tttatatatc 121800 tgaagcttct aataattcat tatactgttc tatttgatga tctaacatgt aatctttata 121860 atacgaaaca aattcattta ctttaccaaa tattgaagat aatggaatga taattttacc 121920 tgcatgagct aattgatgat ttgttttgga tagtaatact aaacctactt tattatcgaa 121980 atgtaatttc ataactcttt ctgctatatc tattgatgta aattgttcat cttccattat 122040 agctctatta actactattt ctacaatctc atataatgta aaaggaaagt gatgatattc 122100 cattgtaacc atgtcttctg ttaaatttga cattgttata tcatttttta gattgtattc 122160 ttcttttaat attgataaat actttttata ttcatttgat cttcttacta atccttctac 122220 attcttaata aatttcttta aactattttc tgattctatt tcaaagtata aacttgatat 122280 ttgaaattta ctttttttat tactaatgt tgtattatta tttgaatctt tcttgattaa 122340 tatattatta attctattat ttttatttag tttaacttta ctacttgaaa atttcttatt 122400 attaaatttt atatctacat ttttattact actcatttta ttcaattcct ttttattaat 122460 taaaaattaa ttaatttatt atatttatat tctttattta ttaaaaattc tttaattaaa 122520 aatatattta ttaaaaattt attaataata tttatattaa ttaaaattta ataattaaaa 122580 ataaataaac taccccctaa atcccccttc ttgtaaaaca aattccaaac tatatattaa 122640 attattagct cagaaaatta aaaattttta ctaaataata tatctgttac aaaatgtatt 122700 aatctaatac agatatatta atattaaaaa actaaaaatt tgaattaata tatttatatt 122760 taaatataaa tatattaatt ctttttataa gtataattat ataattattt caatcattgg 122820 tatgtttatt tttgaattga atagagaaca tattaagtta atatagattt ttaaattaaa 122880 aatattatag aaaatataca gagatatata acaacctttt attaaatata caaagagagc 122940 gaggattaaa tgagatataa tggctataga atttaatgat tttaatagat tcagtaaaga 123000 tgatttaaga aaatacaatc ctctctattt ttataaagca tttactgaag aagatataga 123060 aaatttagat gatgttatta aatattgtca aggtctaatt attaaagatc agtcaatggc 123120 agataaatta gaatcaaatg actcaatgat ggaatctgat ttatatataa gagctaaaga 123180 tgatacactt gatgattact attcagtttt cgatagagat agtatattaa gaacgtataa 123240 agaaaaaaat ccatactatg gtaaattaag aaatttatat gatattgatc cgtatgactc 123300 aagaacaact agtgattttc aaataataaa agcacttaat aaaactctag atagtaaaga 123360 agagtctata ttattggaaa gttatacaga gtcagtcgaa tattttaaaa aagtaactca 123420 tactagagca tttaataatc aaatattatta cagagaaatg ttttatatgt atctaattaa 123480 tgcaactcta catagatata ttaataaaac tatgtataga atattcgatg ttgatagata 123540 tacaaggaga gatcttaaaa atgcatttat atctaatggt ttggattact ttgatgagtt 123600 cccacttgaa tatcaaagaa gaacttacaa aagattaaat gattaatta gaaataaagg 123660 cactaatgaa atatttccta taattgaaga aatattctct attaattcta ttgatattaa 123720 taaatattat ctagctaagc atccgaatga tttgaaattt tataaaacta atgtaaatga 123780 taatttcaat ccttataaaa ataaccaata tagctacaat gaaattgtcg atcttgatcc 123840 atattggaga aatactaaag aagaagttat ggataaagca tttaacgtta tacaaactaa 123900 atatttgtct actgatgctg ttatagatat aattaataac agtaaatctt tatcattctt 123960 atacagttta attaacttaa tgaaagaaga taaaaatatt atcgaagatg acagtttcaa 124020 tatgactaat acaagaatta gttctagaaa atttaatgtc tttgacggaa ttgttacact 124080 taatacactt gtcataaatt atattaaatg gaatgataac attaagaatg ataaaaatat 124140 gaatatatat gcgtataatt ttaattcaga tataaaagat actgtagatg atattcgtaa 124200 ttatatttat tctagacaat ttgataaatc agactatact gattttgcta gagagttaaa 124260 tttccttaat attaagaaat ttaaaaatag aaatacacta agttatgaag atattataaa 124320 tgaatatgaa tcatctgact tagctcaaag acaatttaaa ttcatttctg aaatgttaac 124380 tggtgaaaat ggatcaacac aattagaata ctatattgaa aatgatttaa ttattgatgg 124440 tatgagatat ttatggactc aaatatcaaa cccagaaaga aacttcttat tcaaaaatat 124500 ttcttattat gaaaacttta tgaaaatata taagaaattc ttaaatgtaa tggtaagaga 124560 tggaagaatt gatagagaag atgtatataa aataatgatt gaagacgaat caattgataa 124620 agaattaaaa gattttgtta aaattatgaa tgttagattt ttaaatgaat cttacgatag 124680 atataaagac aataagaatg ctgaaaatat tgaaaatata gttactgcag tcagaaaatc 124740 tatagactat tcaattaaga ataatcaata tacttctaaa aaacaaatat ctagatatcc 124800 tgcattaaaa tcatatattt cagatatatt agtttatgat gattctgata aagatttaat 124860 aaatatttat gatattatta atatgtataa gcataatgaa aaattccgta aagaactaga 124920 agaattaata tataatgcga atgatcctca tttaagagaa aaatttatta cattgcataa 124980 acaactattt atcaataatt ctagtaatga tgtatttaat ggatttaaga cctattcaga 125040 ttatcttaaa tttaaggaac ctgatttgta ttattatact attgtagaat cagaaatata 125100 tgatgaagat acatttgata gagaaactat ctttagagaa agaatttttg aattagttag 125160 tagtattgat aatcatttaa atttaaaaga acagtatttc actaatagta attttgtagg 125220 tatagttaat tttatcagag attatattac tattttaatt acattattta aatcttattc 125280 aactgattta atttatacta gtctattatt taaattagac gataaatttg aaaatagtat 125340 acatttaata gatgaagcca atgttaagta tagtggaact tctaaaaaag tagataagat 125400 caatacactt gacaataaaa atatcattga taaaattaat agaaaagaaa gtattgagac 125460 taaagatgaa ttaaaaatct caataattaa gaagggagat taaaaagctt gtttaatttt 125520 gatagatttt caagaagact tgttgaaagt aacgctatgg aacaagaaaa aatagatgag 125580 ataagctcaa gagtggaaac aagagactct aacgctatta atatcaaatc agattttaaa 125640 gaagatatag gaaattatat taaaggtatt gttaaatttt ctaatcctag aacaggtgaa 125700 ctaatacatc aagaagaaaa tttagtttta atgagaactc gtgtttggtt attagaaaaa 125760 ttatttggta aaggtatacc ttcaaactat aatgcagata gtactcctga tcgtacaatt 125820 tgtttattct cgattgggtc aggtggagca gatgttaaca atgcagcttt ttctccttat 125880 acagttaagt attcggatca aaaattaaat agaccaattc catttgtagt agaaaatcca 125940 gataaagaaa actctgattt aactgcaaat aatcctagta tgattgaaga attatctgat 126000 gaacagagaa gaaaatatta tcttcctgaa gataaacaag atggaaccac tagtttctat 126060 ggtaaacgtt tactaatgc aactaaagaa aatcctcttg gagatcaaa aggatggatt 126120 attgataatg aagatggttc agtagcattt tcattaaaaa tgtcagtaga accagatgaa 126180 gctagaggtt ctatcgtaaa tgaattaggt ttatggttag ctaaatataa tgaaactgaa 126240 aataaatttg atggtactga attagctaca agacttacat ttgatagtcg ttctttaaag 126300 aacttatcag atggattaga tatagaatat attatttata tttaataaaa taaccacaac 126360 gataaattaa tatcgttgtg gtatatttat tttttatctt gttcttttat ctcttctaat 126420 aggatttcat taaaagtaga taacttatct attacttttc tttgatttct attttctttt 126480 tctatcatat taattcttat agatatatct tccaaattct taaggattaa tttagttctt 126540 acaattaatg gtagacttat caataagaaa tatattaaga ggcaaaggat aacaagctgt 126600 atcaatagcg gtttcctcca gtacttacat tatagaaaaa attttataga aaagggagcg 126660 ttgatgaaaa tactatgaat tataaagaat cgtttaaaga atttgacttc agcagagact 126720 ttgaagctgt agtcatagat aactcagatt ttgatacaaa atatgaagtt aagctatttg 126780 tttttgaact aataatgacc accttgcaag attccccaag aaatatcaaa agaaatctat 126840 atgcatcaaa tattattaac atagaagatt tagatatatc tgagaatatt gatattggaa 126900 attatttagt atgtcaaccg ttgatgaata atgatcttga taaaccttta agaaaacctg 126960 aattatatga cagagtttta cttaaattcc ataatgcaaa tcctaaattc ccatattatt 127020 acgatatgca tcttccaaga aaatataaac ctgaagaacc tcatattcct aatagaagac 127080 aaatcaaagg aaattattat agattgctta tgtatagaga agaaaacatg acaggaaatg 127140 atgttaatgt agtaggaata acattaaacg gtctaggata ttctgtcaat aaatatgata 127200 gtaaaaacta tatattcgat agaaccatgt tagaatcatt gttacaattc caaaaagata 127260 ataaccttaa acaagatgga gacgttggac caattacatt taacaaatta atagaaaaat 127320 acaatgcaat tagttattgt tagaaatgag gaattaaaaa atgtattatg aaattaaaca 127380 agatagacga agaagaagta atacctttca aacacatata ataattactc atatgaataa 127440 tttaatactt aaggaaaaca aatttagtga tagagattta cttaaaggat cttataaata 127500 ttcttggggt aaagttcaga attatctaat tagacatgct aatattagag cattacctat 127560 gcattattat gtggaattaa tagataagga ttatgctgtt atggaaggat tatccgatta 127620 taaacctagt tattaccttc aagaattagc agataaagga attatacctc agaaatataa 127680 aaatagtatt ttaatagctg tggctgatga ttttaattta tataatcctg atgtgaggat 127740 gtttaaacat ctagcagata aattattagt gcctttatgt aaaagacatc gattaagttt 127800 tcatgagata aaattattag atgaaattta tagagatgac tatcttgatc atcttgatga 127860 aaatcgtttt gaaactaaat ctatgaatag atttgataaa cagagattaa aaaatcaatt 127920 taatatctat aatgtaatga aataaaattt atttatattt tgttactaac aatataaata 127980 tagaaattta gatttctata tcgttttacc ttttgttttg tcttatgttt gtgctctgat 128040 ttcaaagtca ttttgctctt aacttcgtat agtataaaac tttgctattt ataatttttt 128100 tagctaagtt aataaagctt ataagcttta ttggacaaac tgccatgtca aatttataaa 128160 taacttacaa tatattagcg tattaagttt ttataataaa aaaattattg ctttcgctta 128220 atgattaaat ttctatttta atctttattt atgatttact ccttatataa ataaaaaata 128280 aatccccaat accatagaaa aatggtattg gggtatttta ttaaccgaaa tataatttct 128340 ttctgttact attaaatata gaataatttt ccatcttttc tactaactct ctacgtttat 128400 ctcttgcttc acgtaaatca tccatattaa gattaattc tccaaaagta gtttgtaagt 128460 tctggaatct acttctcata gcatataatg atatttgaac atcataagaa gctaattcta 128520 agaaatagtc atgcatatta tttggtacag aaccgaaatg tttatcatga taagtattca 128580 gaacgattag taaattaaca gaaccaatta cagcagaact taatatttct attttattag 128640 gatgatgata tctaaaagta gatggtgata aattaattgc cattaaatca gacatcattt 128700 gactatctat aggatttccc atagcaaatc ctgcataagg actcatattg cctgcatatc 128760 cagttaaatt agtaacagga ttattagctc caattactct attaatatta actataggat 128820 tctcagaatc tatatagaac atattagtag ttccttctac tttatcttct ggttttataa 128880 ttactctttc ttgcttagga tgaaatttac taaatgtagg aatagtgaat ctttctactg 128940 ttttaataat ttcatcaggt tttaattcta gatcagtgaa catgaaacct acatcacgtt 129000 caatatagtt aagtatttct gtattggtta acataacctt taatcacatc catacatatt 129060 atttgaagtt tctatagaaa tcatcaagtc cattaagaac agattcttct aagaaaactt 129120 taatagtttt attactttct ctaattgaag ctaattgaga acctttatca taactgatat 129180 tagattcatc aactccagca aatcccatat cttctgcaat gtattttaca ttatctgaat 129240 tttctttaat ataagttaaa acttctctag gagagaattc agtaatttta ccattagcaa 129300 acatatcaat tgattcattt accatttgta aatcattagg attatagtta ttatgacctt 129360 ctgaaataat attttgaata taagaatctt gatgagatgg aattactacc caatcataac 129420 aaattaatct taaaggctta gtaacttcaa cttcaccaga aggtgttcta ttaattttac 129480 tgaaaccacg cattgagaaa gatacgtcag atttttgtcc aattaatcct ttcatatctt 129540 taccagctgc agtttgagct gtttctactt ctcccattaa tttattacca ttccaccaag 129600 ttctagtaac aatatgagaa atattgcgtt gatcaatata catttgacgt ttaggttcat 129660 cacttaaggg atggccactc tcaccataaa aagttcttct tgctaatttt tcttgtatta 129720 ctggactatc taaaccactt tgaataacat ctttacgata aacacgacca ttacggtttt 129780 gtctatccgc ttcttgtaac tcagcaatga atctaaccga tttattatta tcttgaacca 129840 cttctggttg agaagttgta ttagattcat taataagata agcttttata tctttagaca 129900 tttatttaac ttcctttcac atattaaatt tagaatattt aaatgtttga taagcaattt 129960 taacaataga atattaacct taatgaaaat atgaatagga tgtgaaatac ttgaagaatt 130020 tcaatgaagt agaaagtgaa ttaaaatatt tcatagaaca aacagataac gattcttttc 130080 ctgttgattt atatgataaa ttaattgata ttgaaaagta tgcagatgta gattctttta 130140 caagtgatca agttaggaaa tcggttaaat atcttgttgc tttaaaagat tcactagaaa 130200 gatttgaaat tgaaaatgaa cagtctgaaa tggcagttaa tatggttctt cataaaatag 130260 aatttttaaa agataagtat aatactcttt atattaataa acgtgttcca aataatggtt 130320 acatagataa tttatataaa gaagattca gttctaatat taatacagaa tttaatttta 130380 aacaattaac tgtagcatta gctgaaagtc ctgctgattc taaactagaa agaaaagctg 130440 ttattaattt cttaatggaa ggtaatatga attatcttaa tgaatcttat gacgatgatg 130500 atgatgaaga ttatcttgat ggtcttgata gtagttttga aacttctaaa gaacctaaag 130560 ttgctgaaaa gaatttaaat agattaattg gttctgttaa aaaagcaacc gcttcttcta 130620 aaaatatgaa tgataaacaa ttagctaaag ctaatcgtat tagatttgta agagctttat 130680 taactggaat tttattctgt atcggtttaa aaattagttc agcagctatt ggtaaagcta 130740 aaacagcttt aatagggtta ttgactgtaa ttgtttataa tgcaagtaaa ggtaatgaac 130800 ttaatagact tatcattgta ttagaagaaa gaatccaaac tttagagaat agaattgatt 130860 cgactgatga tggagaaaag agaaaagaat taagaatatt aaaatcagat ttagaaggtc 130920 aacttaagaa agctaatttc caaaagaaat ctattgagaa aactaaaaat gcgatttctc 130980 gtggagatgt aaacgatagt gggtcagcgt atgactatta ataatagaga tcttttatct 131040 gaatcaatta aaaaattatt aaatggtaat aatattctta atgaagctga agatgatgaa 131100 actaataatg attcttcaga tactaataca gatgatacaa gttcggaaga tactactaat 131160 gataatgaag aatcttcaga agaaaattca gaaacagaag aagataatca agatgatagt 131220 aatgaagatg attctagtac agatgactct gaaagtgatt cagaattaga tgatggttca 131280 gaagagaatt cagatgaaga caatccttta gacgatcaat ctgaagaaga aaataatgaa 131340 cctaaagaaa ctaattctga taaatattta aaattacaaa tatttaataa attaaatgat 131400 ttaatagatg tttcattaaa atttaaagat attgtaaatg aaaagaatat ggaatctttt 131460 gataaaagtg aaaaagaaaa aatgagtgaa attacagtac agacttcaaa taatttagac 131520 agtttaattg atagtattaa tttatttaac aataaattta taaataatat tgatgctgat 131580 aaatgtgaga aactttataa gaagtttgaa aatacttata atgaaatctt caatatttat 131640 ttaaaagaat acaataaatt gaataaagac aaaaaaagca aatagtttta tatttcaaat 131700 tttattccgt tttattaata tttataaaat taataacatt aacatatgaa aagaaatatt 131760 tcattacaaa taatgattat tttttataaa caaatttata taataaaatt aataaatata 131820 aactacacgc taatatattt aagaaaagga gcagaaaaaa tttatgttaa acccaaacag 131880 aattaaagat gaattttcgg ttcgtttaga agatatcgaa aactctatta atgaatcata 131940 taaccttagt actatcggcg gagatttcgc tgctattgct actgacgatg cagtatttga 132000 aagctataaa gatcaattat tagaaggttt tgacgctgct gaaggagaag ctttagctgg 132060 aatgttagat aatactcgtg aagaaatctt aatggaatct tcaatgggac ctatccaacc 132120 ttacgcttca ctttctatgc ctattttagt taaactttgg gctcgtttag ctttaactga 132180 agctttacca actcaagttg ctaacaaacc aaactttaca gttccaatct taactccata 132240 tgttgtggat gcagatggta acaaacatgc tttaccagaa tcaattaata acacacctga 132300 aactttagtt ggattagttc aaattaaaga agatatcgca gttgaaggtg gaaaaattac 132360 tgattacgat ttatttactg gattaaaaga aggtaaagaa gttcgtaaag gtattgaccg 132420 tttagaccgt aaattcaaaa tcgttgaagc taaatggagt gattcattcg atgaacgtac 132480 ttcagctgca ggattcgttg aattaggttc taatgtagtt aaattacaag acaatgatac 132540 attagtagga caaattaaat atcctacaaa tggtgatggt gaagttgaaa ctgacactgt 132600 cttaggtaaa gtagatgttt ctacaggtga acttactttg acttcagctt caggtaaatt 132660 aactgatgtt aaagttaaag gttatgtagc ttctgaacaa catacttcag ctacaaacgt 132720 tgaacttggt ttaactcgta aagacgttgt tattgataca gctcaacaca tcgaagctac 132780 agtacctctt gaagtaattc aagatatgaa agctacttat gatatcgatg gagttgctcg 132840 tttatcagaa actatgtctc aattatctag tcaaaaagtt gacttagaca ttattgaatt 132900 cttagatcac gaatataaag aaactgatgc taaatatcac ttcagcttcg atgtattccc 132960 acatagtgat tacagtgctc atcctaaaga ttggttagaa ggtctacgtg aagtaattga 133020 ccacactact caatcaatga aaaacgatta caaattatat gacgttcaat tcgttatcgt 133080 tggtaaccca ttagacgttc gtttaatccc taacgtttct tggactttca atggtggaga 133140 ccgtaacgct gatgcttatt ctaacggaat caaaattaac tattcattag gtgctgcttc 133200 aggtactgct aactaccgta ttatcggttc tgacttagta cgtcaaggtg aattgactat 133260 tattgctatt cctcaacaag acaactataa aacattcatg ttctaccctt acacattcaa 133320 cgttgtaaat ggtggaggtt acctaaatac tcgtaaccct aatgttccta acatgatgat 133380 gactcgtaga tatacagttg aatcatttgt tccgatcatt ggacgtatta caatcaaaaa 133440 caacaacggt tcagtatacg ctcgataaga gtagtacttt atcattgcta tttatattac 133500 ccatacatct ctctgaggtg tatgggttta ttttatatca aaaaggagaa tataattcat 133560 tatgaattta caagaagaac aacaattaaa taaaattaat aaaataatga atatcaatga 133620 agatgctttt aattttagta aaaatacttc attattgaga gaaatagatg aagaatttaa 133680 aacattatta gatagttata attatgataa atctgatttt gattaattg ataaacatga 133740 aataaataaa atatctacta atatttctaa aatcactaag aagctattta atactaatat 133800 gaaattaaaa tttgttgaag ctgatcctaa aggaaaagat aaatttagag ttgaatcaat 133860 tgcaagtaca attataaaac cagaacaaat tagaaataca tagatggaa tttctaaaat 133920 agttatagaa gaaaagaatg gaatatatta ttctaaacct agagaaattg aagtttttat 133980 ggagttatca tctttaagat actttttaga aatgaaaaag aattctaaga aggtatcttt 134040 ttctaatttt aatgaaagag tttgtacttc aatattatta catgaaatag gacataattt 134100 atttttacct attgaaatta aagtaataac tcaaggtaaa gaacctgctt ttgagcttaa 134160 atataaagac aataaaccgg tacaatttca atatactaaa gatatagaag cggacactga 134220 tagaaattta aaattagctg gtcctatgat aatttctatg acactaatgg ttgctatttt 134280 aacttcatta acaggtgtag ctgctataac tggaattgct tctatttttt ctttctttaa 134340 attaggatca atggataata aaagagtaga aaaaatgaat tataatctat ctgaaagatc 134400 tgctaatcaa ttacctgctt tatatggata tgcaaaagag aatataatgc tttacgatat 134460 ggtttatgct gcaactaata gtaaaatgga aaaaactaaa aataatattt tcagtaaaat 134520 atttagagga ttaatgtatc ctggtagatt atttattaga aattataaag actattcatc 134580 agattccatt gataatacta ttaagactct taaatttgaa ataagtaacc ctaataatag 134640 taaagaagtt aaagaaagtt taaaacaaca actttctgat attcaaactt tgatgaagaa 134700 atcagataga atgtagataa gaaaagtgag ttgaaataaa tatgactact aaaccaaaat 134760 taaagaaaaa agtgtattac gattataaaa ctaataatgt tagtttttta agagtagcta 134820 gagatcttaa gaagaacaac gttagaaatt atggtattcc attaactcta tacgataaaa 134880 atcttatagg agtagatcct tgggatcctg agctttctga tgaaatgaaa actcgtgtat 134940 taagagaagc taaaattaat atatggtttt atcttagaga agttatccga gttccagttc 135000 ctggtggtaa agtaatgtat gaacttcata ggggtaatat ggctatgact ttctgtatgt 135060 tgcataacct tgatacagct ataatgcttc cacgtcagca ctataaaaca tattcagctg 135120 tatgttatta ttcatggata atgttattag taggtagtaa ctatacaatg ctatttacac 135180 ataaatcata ttcagataca acggaaaact taaaacgtct taaaaactta tttaaagaga 135240 agtgtttacc tgaatatgta ttagctaact ttggtgataa aaatgataga gataaaatta 135300 atgaatttca attagctagt aataataata cgattaaaac agtttcacct ccaactaaca 135360 gtgagagtgc aaacaaagca ggtcgtggtt ctactgtacc tatggtttgg ctagacgagt 135420 gggcattcat tccacacaat caaacaatgt ttgaagctat gagacctgca gtttctacag 135480 catctgcaat agctaagaaa aatggtacac cttatggact tctaattact actacaccta 135540 aaatgactgg gtgaaaataa attaaaattt attttaagga ctttattaat tgctgggaga 135600 gccttagagc ttaatcaact acaacgtaat tagaaataat aaacgtgaat gtctaaaaat 135660 gattaagatt ggtcaatcag cagctaattt ttcaatttat taaataatga acaactcctt 135720 atacaaaaga cttaggagtt ggtattttga atttttatga aaaactaaat aaaaaattta 135780 ataatagtat aatagcaaaa gaagaatata aaaatggtaa tgaaaaaatt aagttctatt 135840 gcaaaaattg tgaaaattat ttttattcta aacctagaaa aattattgaa tcttcatata 135900 aatcatgtca tttatgtaga aaaaaagaaa aagaaaatat tttcaggaat aatctaatta 135960 aaatgataga taatgaaata tatgaaataa ttgaaatgaa aaatcctata aagaataatg 136020 aaaaattttc tttaaagcat agaaaatgtg gaaatgtatt tcatatatct gtaagtaatt 136080 ttaaaaaagg tagaaaatgt ccttactgtt ctaataaatc tatgaaaaga gatcaaagtt 136140 tctttttaga gaaaataaat aatatagatt ccagtttttt aaaaaattac gaattagaaa 136200 gtgattatat cggtgttaat aaaaatatta aaattaaaca caaagaatgt ggaaatattt 136260 ttgatactac tcctaataga atatatagag gtaatagatg tagtatttgt tctcataaat 136320 cagataagta taatttagaa gaagtgaaga atattataga aaaagataaa aaatttaaac 136380 ttatgtctaa ttattatgaa aacaataaac aaaaattaaa aataaaatgc attaattgtg 136440 gtaatataca agagaagaat ttagtttcat ttcaagataa aagaaataga aaatgtatgt 136500 gtgaaaaata ttctatacca attcaatata taactaattt tctaatgaat aaagatataa 136560 attttgaatt agaaaaaaga tttgataatt gtaggaatat tagaccttta ccttttgata 136620 ttttcataaa cgattttaat attttaattg aatatgatgg agaacaacat tttaaaccga 136680 tatatggaaa agaaaaattt aataaaacta aaataaatga tgaaataaaa aataattttt 136740 gcaaaaaaga aaaaatagaa ctgattagaa taaattgcta tgatgattat aaagataaaa 136800 ttgaaaattt agttcaacga ctatcgaaag ttgagtatac atcgtgagga tttatacaat 136860 ataaatgagt agagtacagc caagcggtta gtaattaagt gatattagct taatataatt 136920 ctattaaatg gaaacataaa gatttctaaa gtaacgttta gatttaagat atagtctcaa 136980 cattcaggga aaacctgaag aagttcataa gagaactgat atagattagc gatctatatt 137040 gaagattttg agtactttag atgttcctca aggacaattc ttctttgaac aaatgaatga 137100 tgcggctcaa tggacagaaa aaatatatga ttattacatt aattctgaag aagaaggtaa 137160 tgaaaaatta gaagagtata tggatagtaa ttcaggtaat tcatttattt atatagaata 137220 ttcatataaa gaattaggaa aagatgacaa ttggttagaa aagcaaaaac gtcaaatcgg 137280 ttctttagaa gctgttaaac gtgagatact tcttgaatgg gcatttagta atgatgattc 137340 tttatttgat gaagaacaaa tgtctgagtt atctctatat gcaaataaag aaatatataa 137400 cactattgac tttaaaataa atggtaaaac ttattatgtt catatggtta aaaagatgga 137460 aaatatgcat gaaaagaact ggcttgttgg tattgacata tctggcggtc ttggtcgaga 137520 taatactgca tttactgtag ttgatccggg tacattagaa ccagtaatgg tcttccaaaa 137580 taatattaatt aatggtccta ctttcagaaa attaattaaa gaacttatta cactttatat 137640 acctaatgca gtattaatac ctgaacgtaa ctatgctggt acagtaatga tagaagatat 137700 gattcaaact gataatattg gagataatat tttttattca ttaaagaata gaacagcaga 137760 aaaacaagtt gaagttaata aacaagtatt taatgaaatg cctagacata gcactaataa 137820 agttactaaa caagtaagaa gatatggtat cgatacaact aaaaaatctc gtgacttaat 137880 gcttaatgaa attttatcaa tgatagttga agaaaagcct tatctggtta ataataaacc 137940 attattccaa caaataaaat ctcttcaaat gaaaaaaggt agaattgatc atcctgatgg 138000 cggtcatgat gacttactta tgagttattt attctgctta tacgcatact attatgaaaa 138060 agatattaag aaatttgtta aagttaaata cggttcaata gtatctccaa ctggagaaaa 138120 tgcggaagag attgaaaaag aaagacaagc tagaagaaaa gatattgcat ccataaaacg 138180 tattggtgga attattgatg gtaattctcc tagcaatcct ctattacaga ataataattc 138240 cgctccaaat caaaaatcaa aaagaataat gaatttattg gattgattac aataaaggta 138300 atggcataat aatttgtcat taccttttta ttatcacaaa tttttattat tccatcttaa 138360 ctaatttgta taatagaatt tcaagaataa ttttaaatta gaattttttc taaatttaat 138420 agaataatat aatatataat aataaaacgg atggtgaaaa taaattggca aaaacatatt 138480 taattgacga taaagatgat ttagaaatgg taaaagaaga atatgatgaa gtcattatga 138540 atatatctga agacattatg attgataata ttaaagaaca aattgaagat tcaaattcaa 138600 gacagttcta tattaatcaa tatcataaag atttctttga atactttgaa attagattta 138660 aatttatttt agaaagatat aaagaagata atgatatctt aattaaaact aaacaagttt 138720 atcatgatat tcttaatgaa attcaagaat ctattgaaaa tacttatcag ttttctttag 138780 aatttccaga agatatttta attgaagata aagctcaata cattaaatca ttgtataatt 138840 tctttgtatt aaataaaaaa gaaactttaa ataatttatt tattaactat attgagaaga 138900 atataatgca attagctaaa acttataaag atagtatgga tgaagacgtt attaactctc 138960 tttcatataa taacttaaag aaaactattg ataatgatta tacaccttta gtatattcta 139020 ttcctgaaat tattgatggt attcatattt ctgataatga agatgtaata gagactatta 139080 tctatgatga agaatctgaa ttaaataact atcaaattga taaaatgtta gtagaacaat 139140 ctgtaacaga tgttagattt gataatcatt taattaatgt atttagagat tcttttatag 139200 agaataatgt attacatcga gaagttcaat actattttat agataagtat aaataataac 139260 atataaggag aaaagctaaa atgactgaag ataagagcaa agaattagat ttagaaaaat 139320 tagaacaaga tatagaacaa gctaatgatg aattcgaaaa agaaaatgaa aagattgaga 139380 aagagttaga agaaacaaaa gagggaatta ataaagaaat agcttcttat tatggtaaag 139440 atagtattag tcttaatgac actatttcag tagatgctaa ggttaataga taccaagaaa 139500 aattagactt tattaatgga gattaagtt ttgatagtga agatgatatt cctgaaagac 139560 ttaaaccttt taaaaatatg gaaataaaag atactaaaca aattgaaaat attattcaac 139620 aaattaaaga cagtaaagag gctaaacatc ttgtagaaaa tattactatt agtaaattac 139680 ctgttaatga taataaactt aaaaaagtaa atgaaaaatt aaatatgaaa atttacagat 139740 ataataagtt acatggtaat gaaaataatg aatataatta cattgattta gaagatattc 139800 ataatactct aaaaaatgct ttagacaacg atagtttcaa agaatcaaat acattataca 139860 aatttatgtg tgcattaggt tcatacatgt cgcaaaatta tgaaaaatat ccttactata 139920 taaaatctct ttctgaaaat gttgactaca ttggaaaatt cggtaataaa tagatcaga 139980 acgaagactt tatcaaagta ataaatagta ttcttaagaa atactaaaat atattattaa 140040 aaattataag aaagaggttt gattaaaaga tggaacaaat taaattttat actaagaata 140100 actgtgctaa atgtggtttc agtaaaatgt ttttaaataa taaaggtgtt gcttacactg 140160 aaatcaatat tgatgaagat gaaagtgcta aagaagaact tttatctaaa ggataccaat 140220 cattacctgt aattgatttt ggaacagatg taatcgttgg taatgatcct gctaaattaa 140280 atcaaatttt atctacagtt actgcttaat taaatataaa ggagattata attatgcaaa 140340 ctatttttaa tagtccagaa gaagtagatt ttaaaaaatt agctgagaaa gctagaaata 140400 atgataatga attaaataca aaagctgttc atgaaggaga atacaattac aatttcagta 140460 ttgaaggttg gaattactca ttcagttcag atggaactta ttggaaatgg aattatcaac 140520 aagttaatca ataataatga ttaataaaaa acgatctatc acagagataa tctgtgatgg 140580 atctattttt aacgaaaaat tttatatttg gagagattta aatgaaatta ctttatttct 140640 cattaacagg aaatagtaaa aaatttgctg agaaattaga tagctctata gtaggagaac 140700 ctattgaact taatagagat aattgtgatg atattaaaat ggatgaagag tatgtattag 140760 tatgtggatc ttacaatact cctcacgcta tttacaatca tgtagaaaaa ttctttaata 140820 atggtaataa tttagaatta tgtaaaggta taattggctc aggaaataga aacctaaatt 140880 atcaattctt aactacacct aaaagattat gtagtgattt taatttagaa ttgattgcag 140940 gagtagaatt gtttggaatt aaaaatgaac atttagaagt aaataaaaaa ttagaagagt 141000 tatctaactc tagtattata aattaatata ttgtaaggag acttttaata aaatgccaaa 141060 agaaatagac ttaacttcag aaaaatttaa agattattca tataacgaat taaactcaag 141120 aggttcacaa ttaaaagatg gtaatttaga tttagaattt gaattagcat ctgttaaaaa 141180 atatttctta gattcagtta ataagaatgt aagatacttt aaaacatata aagaaaaaat 141240 taattattta gttgataatg attatattga tggagacatg atcagtaatt atgattttga 141300 atttattaaa ggattaatga aagaattaat ggcttataaa catagattca ctcgtctatt 141360 aggagctaag aaattctatg aacagtatgc aatgaaagat gatgcaggag aaattttatt 141420 agaactatat gaagatagaa ttttatttgt agctttatat ttagctgatg gtgatgaaga 141480 attagctaga aatattgcta atgaaattat tacaggtact ttccaacctg ctacaccaac 141540 attccttaat gcaggtagag tacgttctgg ggaattagta agttgtttct tattaactat 141600 ggaagattct ttatcatcta tttatagaaa tatttctaac gtggcacaat taagtaaacg 141660 tggtggagga attggagtat ctttaagtaa tttacgtgct gacaatgatc caattaaagg 141720 tgttgaagga gcagcttcag gagtagttcc agttatgaaa gtatttgaag acacattatc 141780 gtatgtaaat caattgggtc aacgtaatgg tgcaggtgca ctttacttaa acattttcca 141840 taaagatgta gtaaaattct tagatactaa gaaagaaaat gctgatgaga aagtaagatt 141900 aaaaactatt tcattaggtt taacagttcc agataaatat tatcaattag ttaaagaaaa 141960 taaatcatta tatacattta gtccatatga tattaaaaaa tattacgatt tagatttcga 142020 tagtattgac tttaatactt actatgatat ctttgtagat gataaacgta ttagcaaaga 142080 gaaaatgtat gctcgtgatt tagaaactac tattagtaaa ttacaacaag aatctggcta 142140 tccttatatc attaatattg atactgctaa tagagctaat ccaattagtc atggtacaat 142200 taaaatgagt aacctatgta gtgaaatttt acaagtacaa tacccttcat tagttgacga 142260 taatcaacaa tatgttaaaa caggaacaga cgtttcatgt aacttagctt caactatcgt 142320 acctggttta atgaaatcag aagactttgg taaatcagtt ggaactatgt taagaagttt 142380 aaattcagtg gcagaaaaat ctaatattga agctgtacct acagttaaga aagctaatga 142440 tttattccat acggttggtt taggtgcaat gggattacac acatatttag ctgaaaatca 142500 tattcaatat ggatcagaag aatctaaaga ctttactaat atttatttca tgttattaaa 142560 ctattggaca ttagttgaat caaataaaat tgctaaagaa aaagatgaat cattctactt 142620 atttgataaa actgaatatg ctgatggttc ttactttgat aaacgttata ttggtaaaaa 142680 tattcaacca cgtactgaaa aagttaaaga attatttgaa gatatcttta ttccatctga 142740 tagtgattgg gaacaattaa gaaataatat cgttatggat ggtttataca atcaaaatag 142800 attagctgta gcacctaatg gttctattgg ttatgttaga gaagtatcac cttcaattca 142860 ccctattgtt gaattaattg aagaacgtgt agaaggtaaa acaggtacta ctttctatcc 142920 agcaccaggt attacaccag ataactttga ttactttaag aaaaatgctt atcaattaga 142980 tatgaagat atgattgatt tatattcaga agctcaatat catgtagatc aaggtatttc 143040 tatgaatatt tatttaatga atgaacttga tccagatctt tatgaatgga aaaaagattc 143100 tttagataaa gaaactacta ctcgtgatat tagtagatta cgtaactatg cttacagtaa 143160 aggtattaaa tctatgtatt atactcgtat ttattcacca gaccatgatg aaaattctca 143220 aggtattgtt gaatgtgaat cttgttctat ttaattggag gtatttaata tgacattaaa 143280 agaaaaattt gaaagtaaat atagaaattt aaataaagaa ccagaaattt taattgtagt 143340 aattaaacta ccaagtggag ctaaggaagt aatttccaat agctctgact tggataataa 143400 agttcattat tacttagaaa attatgatga tcaatttaga catgttagag atagcaatgt 143460 acagataatt gatttcgtat tagtttaaaa ataaagaaaa aggatgaagt taaatggata 143520 gaggagattt cttaacaagt tatacaaaag ataaaggtta ttatacacct gtaaattgga 143580 atagagtaga tgattatgta gatattatga catatgacac tttagtatct caattttgga 143640 catcaacacg tattccagta tctaatgata ttaaagcttg gtctaatact gatgatttaa 143700 ctaaaggagt agttaataaa gtatttgctg aattaactat tttagataca cttcaatctc 143760 gtgaaggttc tgatgcttta atgcatagtg cattaactac attagaagaa gatgtattaa 143820 gaaatatcgg ttttatggaa tcaattcatg ctcgtagtta tagtactatt tttaactacat 143880 tatgtacttc aaaagaagta gatgaaaact ttgaatgggc agaaaataat aaatatgtac 143940 aaaagaaaat taaattaata aatgaagctt atcaatctgg agatattctt aaaattcaag 144000 cagcttcagt attcttagaa tcattcttat tctattcagg tttctatact cctttaagat 144060 taaaagatag tcttaaatca gttcttgaaa tcataaaatt aatcttaaga gatgagtctg 144120 ttcatggttc atatattgga tataaattca gtaagagatt tgaaaaatta agtgaagaag 144180 aaaaaaatga aactaaaatg tgggtaaata acttactatt tgaactttat caagttgaat 144240 gtgaattcat tgaagaagtt tatactgaaa ttggttgggc agaagatgtt aaattattcg 144300 ctcaatataa tgctaataaa gctctatta atcttaaatt agatcctatt ttcgaaacta 144360 ctgaagaaga tgtaaaccct atcgtaatgg caggattaaa aacttctaca ggaaatcatg 144420 acttcttctc tcaagaaggt aatggttatt tattaggtaa agctgaaaat actaaagaag 144480 aagattatga ttcaatcgat attaatgaac ttaataagaa tatcattgat tcgtataaag 144540 ataaagcaga cgatagattt agtcatagtt actatataga ttaataaaaa ttttattgaa 144600 tgattaacaa atatagtata ataaaaataa aaaaggtaat ttgtttttat tatgattaat 144660 ttgcatacat ttcccctaac attcttaatt gattgttagg ggatttttta cgccaaattt 144720 tgatctgtaa caaagatata ttaattcaat taatgggaaa ggagataaaa tggattgaaa 144780 cttaaagaac ttaaaagaga tggaaattct attatattca ctggtgaaat attagacatt 144840 tacattccaa gagaacaatt caaaaaaggt ttatcagaac atcgtggtga gtatattaac 144900 acgtatggaa tgtttcaatt tgaaataaaa actgagaagc aagctgaaga aggtaaacaa 144960 ggtgttttaa gaaaaatgaa atatcctaac cctatcgatt ttaactatgt agagaatttt 145020 aagtttgatg gaaaactgtc agataacatg gattcaatac aatatgaagt ctttagacta 145080 agaaccggat gtcaatttgt agctaatgtt aatatagaac aatcagctga aactgttaag 145140 aatttcttat tcttattcca tgcaggtaaa ttacctactt ttatagatta taatgatatt 145200 attaaacttc attatgatgt attggatagt aataaagtaa accttaaatc taattcatta 145260 acttatgaat tgattattgc tgaattatgt agatataaag aaaatgtaga aacgccttat 145320 agaatagctt taaataaaaa acaaaatgtt ggccctttag attatattaa ttacaatctt 145380 aaaaaattac ctaaccttaa ttctacattt gcttcattca catttgaagg tatggatgat 145440 actattgtga catctatagg tagaactgct aaaggtggaa cagaaaaacg ttcaccatta 145500 gaagacgtaa tgaaatatta ataagaaagg atgaatctaa taaaatgttc tggaaagtat 145560 caaagaatct cttaaagtta tctagaagta ttttaacatt cattgaactt aattcaaata 145620 aaaagaaata tccaccttat ttagcttttt tagtattcca gaatagtata acaatagatc 145680 aagttcctaa tgaatttaaa gaagaagttc aatatttatt ggatgaaagt tttaaataaa 145740 ttatgattgg tatcattgta tatacttttc taaattaaac atactattat aaaatttaat 145800 tataatataa aatctattga aattaatcac atagatgtaa atattcgaaa ggaaggttac 145860 aaaacatatg gcagacttta tgtatctcca tccttctgta caaacacaaa tcaactctta 145920 tcaaaataat taccctacag ctgaaggtcc tgtaacatta tttgctgcag acacttttga 145980 aaaaggtaaa gatggagtta ttgattttgt aggtactgaa gaagaattta tttttaaata 146040 tggtgaacca aactatacga aatacggtca agctgcttat aacctcgtga actggttacg 146100 ttctggtggt caagcttatg tattacgtgt attacctaaa aatgcaactt actctcatgc 146160 tatattaaac gtacaaagta gagtacaaaa agatggtaaa aaagttttaa cggatgcaaa 146220 tgaattagtt aaaattgatg atgttaaaat tcgtccaaca attgcatttg ttaagaaaaa 146280 taatagaaat attgaagaat tagttaacga aatcacttta gatcgtggta atgaacaaac 146340 agtagacggt tataataata acttcttact tttagcttat ccaaatggtc gtggtgaatc 146400 ttataatgat ttaggtattc gtttaacttt aaatacttca tatgacacta gtggtcgtac 146460 tgaacgtgtt tataacttag aagtacttga atttgacgaa tttagtaatg ttaatgtaat 146520 tgatggccca ttcttagtta catttgatcc agattcaatt tcagatactg gtgaatcaat 146580 gttcatcgaa gaggttgtta atcgttattc taaatacgtt aacatcaaat ttaatctaga 146640 aaacttccaa aatctagcta aagaaattaa tcctaatgta catcctgcaa gcattgatgt 146700 tatttctggt aaatctaaag ttagtattga tggaactcct gagactttct actcagaaaa 146760 aactaaacaa tctgaagata tccatatcac tttacaccgt tacaataata aaggtgtacc 146820 agtaactatt agtggtaacc ctgtattgaa taaacctgat tttaacgatc cagttgaaaa 146880 tgcattaatt tcattagaca atggtatgcg tgaaaaaact ttcgttacag attcagatcg 146940 tctttcttac atgagagatc aatacaaaac tttacgttct gataatttta cagaatttaa 147000 atcattatta aataaaatta ttgtaccggg taatggttta tttgaagatg atgcaggtag 147060 cttacctaaa actattaaag ataatttagt ttctgcaaaa ttaacacaag aagatgtaac 147120 tgcagatatc aatgatgaag aagcagttga agaagaatta gctggaaaat tcaaaccttc 147180 tgaaattaat ttcggtggta aacctgctgg agcagctgaa cgtttagttc aagattataa 147240 cacttatttt gaagattcaa atgaagaaaa tctttctgca gtactttcag gtacagaaga 147300 aattggttct ttattattaa acgaattctt agataacggt aataaactta acgctgctta 147360 cgaattagtt tataaatcta attcaggtat ttcttcaaat cctaaatatc aagctgatgt 147420 taaagaatta cgtgatgtat tggctcaaaa agaccaaatc cgtatctttg gtattcaaca 147480 taaatctaat atcttagata ttacaaatga tattgctgaa ttacgtattg gtatgaaatc 147540 agttactaac ttagaaggta tgtctaaagt attaaatgat actgaaacag aattacgcta 147600 tgtaattgac aacttaatgc ctgctgttcg tgaaggactt cctaaagaag cagttgactt 147660 tattaacact gttcctgatg gtgatgatga agatacagaa cgtgatttag tttctccaga 147720 agctatgtta aactcattag ctgacaaaca aatgttagtt gacgatatta acttaggatt 147780 aatggaagac aatgctgcta accgtgaaga agtattcgta gcttgtaatg aaatcgctaa 147840 ccaattagtt gattaatta acagagctgt ttcagtagct tctgtatata aagttgctcg 147900 tgcggtacgt attgcagcta atacaatcta ttatgatatt tctatcttcc gtaaaaatat 147960 tgatgaaatg attcaaactc gttctaacta tacagaaaga gatattacat tgaatgctca 148020 tcaaaatatt gaattagctg ttgctaactt gaataaagct aactctaaat acttcaatac 148080 taatcttatt gatgtatcta gtccagttaa attcttattc ggttctgatg gtgacttctc 148140 ttatgctgaa gacatttcat ataaagatcg taaaaactct gttaaccgtg aattaattaa 148200 agcttataaa ggtttaattg atgaagaaat tacaaacact aaagcttatc catttgatgt 148260 tgttcttgat gctcgttatt ctaacgaagt taagttcgct atctctgaat tagctaaaaa 148320 tgttcgtaaa gactttgtat tcttagctga tacggttact gatcgttacc cagttagtcc 148380 tgaagatgca attagatgga gaaaagaaga atttgctgtt tcttctgagt atacagctat 148440 ttactctcaa gattaactt actatgatga gtacactggt agagacattc gtttcacacc 148500 aacttatcgt ttagcttcaa tgattcctta tcaagctgtt aactctggtt tacacttccc 148560 aattgcagga cctagacgtg gactagttga aggacataaa gctttatctt gggctcctaa 148620 tgaaccttat aaagaaaaac tttatacttc taaaattaac tacattgaaa aagatattga 148680 tagaactaaa tttggtgcac aaatgacttc tattaaatct gatggtccat tatctaactt 148740 gaacaatatc tttacattaa atcaaattaa acgtgatgca gaaactcttg tttctgatta 148800 ccaatttgaa ttaaatgatg atgaaactcg ttcaattatg ggtacagagt tgaatgctta 148860 tcttactcgt tatgtatcta accgtagctg tgaaactatt caagctgaag ttagtgcaga 148920 tgaatacgat aaatctcaac gtattgtacg tgttaaaatt tctgttaaat tcaacaatgt 148980 tattgaacgt atcttcattg acattaatgt tgaaaaataa ttaaacttat aggatacggc 149040 ttaatataca gtcgtatcct attttattat ataaataaag atcttatatt aaattatacg 149100 tatgaagatg gtatataaac ttctataata tacatttatg taaataagat taatgaaaag 149160 gagaaaataa tatatgattt taccaagtaa aaatcagcgt gtgtttgata ataacatcgc 149220 taagaacaag tggttctata atggacatat gaatcttcaa actcttgagt ttgatccatt 149280 cgtaactggt tattcattca tagtatggac taagattcct tcttgggttg aaaaacaatt 149340 ccctggtttt aaagctatga ctcaaaagaa ctttaaatca ttccaaggtt tagaaaacat 149400 tgaaatgact acaaacgatt atatgcatac gtttaacggt aataactatc gtacagctgc 149460 tagtattaca aaaggaaaca ctggtttcca aatgactcac caagaattct ctggtagtcc 149520 aattaaaaat atgtatcaat actgggtatc tggtatccgt gatcctcgta ctggtattgc 149580 aacttatcct aaaattcata atttagaata tgctgctaaa aaccatacag gtgaattatt 149640 atatattcaa actcgtccag atgctaataa tacatctaaa aataatattg aattcgctgc 149700 ttattacact gcagtaatac ctactcgtat ttctcttgat caccataact acactatgga 149760 aactcatgaa gaagcacaaa ttgagcaaga ctttgcaggt aatatggaaa tttcagcacg 149820 tgtaaatgac tttgctaagt ctaaacttaa tgaaatttac agcttcactg aacaaggtat 149880 gtttgatcca tctgcaccta aaactgctgg agataactta tctgatttcg actataataa 149940 aggtggaatc actggttcag gtaacggaga tcttaaataa tagattctct caaataaaat 150000 cccctaatac taaattaata gtattagggg aatatttttg aattatttat taattctact 150060 gtatatatga caaaatgtta tgtcgtctaa atttactgtt tcatttagta atctttcttt 150120 ccagttctct ccaagatcat atatcatttc tgataatact ttttctgtat aattttgtaa 150180 aggaactagt ttagcatcat atttactgaa ttttcgtata tagttttcat aacttaaatc 150240 gtcagataca tatttaatag attcaaatat ataaggttta aatatcatat atctatcaaa 150300 atccatatca tcatgaatca tcaataattt aggtaaataa taagattcaa taggtacttt 150360 aatttctaat ccttgaatat tatttttata atgaacttca tattttaatt ttctatcttt 150420 ccaatcaaaa ttattaagag cgtaatgtat aggttcttct tcaatataat aatcgattcc 150480 atcatcacta tataattgaa cactatcaaa tgatctagga tcattatctg aatcaatatt 150540 atttaactca ttatcttcat tagtcattac ataatcttca tatataaaat aataattttt 150600 aatattagga tacactaaag cttttttatt aacatctgaa tgttttttga ctgtatttga 150660 atttataata agagaatcaa ataagaaatt atttttgtca ggtgtagtta tttgtatatc 150720 attttctttt ctaagataaa tttcattgat atattcatct atattcattt ctggaaatct 150780 cttatataaa cctaatgtac ataaattgtt atgatcttca tgaactttag caatataatt 150840 tttaccatta atatttacta ccgcttcttc ttgtttagaa ttctttattt gatcattatt 150900 aaattttctt ctaaataata ttttgaaatc atacattcca gattcagata aatttaaagt 150960 attcttaaca gttcctgtag ttaaagaaaa tttatcagat aaactactaa cttcttctat 151020 atttgtagtt ttattatcta ttttaaaagt ttctaaagtt ttaccagttc cctgattata 151080 agaatcatta tctatataga aatctttaat aggtactata gttctagttc ctactttaaa 151140 gtgattttct tgttttgaat agaaaggatt tttagcttca ggaacttcaa cttcttctaa 151200 taatataaca tttatatcat tttctttagt agagaagttt ttatcatatt caaatttaaa 151260 tgtatgagtt ccttcctcca agtatattgg tggctcttca aaatattcat ctgtagcatc 151320 atcatatttt tctaatatag atctaaacca taataaactt ttattcgtag gagtcctaaa 151380 ataacttcct acattatcta taaacacttt attcactgta ccattattat aatgatttcc 151440 agctttaaat cttacttcat aatgggatga tttaggaata ttaattttca tttctaatat 151500 tccatcttct atagtcacat atccttttcc taagaaccta tcataacctg aatctctctt 151560 ataagctcca tcaaattcac tttctctagt tctataaaca tcacctaaat atgcatcata 151620 gaatattctt ccatcttcta ctaacccatt atatataata ccatctatta attcagattc 151680 ttttaatatt tttttattaa atgcatagtc tttaggataa ttattattat ctttatagac 151740 tggtggataa ggttcaattt tcacctcact ttctaccaga ttgttaaaat ttaaatcttc 151800 atactcaata ttacctatat aattggtatc atatattctt tccattttac ctaagtaatt 151860 ataatatatt gtaaataaat catattttaa ttcaccaatt aattcataag gtctttcttc 151920 ataaactaaa acatctttag ttaattcatt ttgatttaat ataggatttt caattccata 151980 ttctttttta atataggaag ctgattcaaa taaattaacc tcaccatctt ctttaaaaga 152040 taattttttg tattcatcag aatcaaattc tatttttaat aataattttt ctttcttttt 152100 agttttagtt gtaatcaatg gtctattttc attatcttta attttagtaa taacgatttc 152160 accattatta tttttatcaa ttaactcttc tattctataa agcttcattg taataactca 152220 actctcttct ataatatttt atgataatgc acttccaata gcactgttag gatgagggtt 152280 tgcttgagat ttataaccgt aaatagtatc atctatttgt tgtttaaata ctcttccttt 152340 taacacttgc atacttcttg aatactgatt ttgcatatta atttgagctt tatctataat 152400 tgatagttga tctcttctaa tacctgctaa acaatcaata taagaaatta aacctgtatt 152460 aaatttcata cgttggaatg attttgatgc cattaagtta gggtacatat ctcttacatt 152520 tagtgaaact gttatttctc tagggaaacc atctgctgtc catgtacctt cttctccacg 152580 aactatattc attgatgtta taatacctgt atgacattca aatctaccag gacagtttgc 152640 tctaacaatg aatggttgtt tatatgagaa aatagaatct tgtaaaggta aagctaatac 152700 caataatgac atgaacggta aatatacatt ttcaaaaata gattgaggat ctccatacgc 152760 actatagaat ttaaattcta agttataagt acggtcaaaa gttgagttca tccatacatc 152820 aggataatac attgatgctc catctaaatt ttccataaag ttaccaacta taccacctaa 152880 tactggcata tttgcaacca tatcattaat gctatcttta atagatcttg taattttacc 152940 taaaatagaa gctcctccaa tacgagccat ttctttttct tcacgtattt cttggttttt 153000 attattaatc tgagaagcta tatcagattg attatactca tgcattgctg attcagacac 153060 actagtagct ttatccgcat aataagctaa accatagttt ttgtcatcta aagatccacc 153120 taaatcaaat gatcctttta atcccataga tgcatgtaat tgacttccca tggtttgtac 153180 gtatttataa tattcactca ttttaggttc aaaactaacc atacgtccat ctttagtatt 153240 acctatacca actaacccag ctgtagtatt tgctaatctg tctaaacctt ctccaaaact 153300 ccataattta ccttcacctg gtttaccgaa tagtttacca tttagtttag gcatacctgg 153360 cattataaat actaatggta aatctaattc aaatgtcctt ttataaatac gtctattagg 153420 atcatctaaa ctggagtaat acataggcat tccaaaaaca tccagttcac ctttaacatt 153480 tctcaattta gttttatcgg atgctccgta ttcagaaatc tcacgactat tacctaaagc 153540 atctttaaat acacctaaat cattttgact tggatcatat tcttggtaag cataatctcc 153600 tttagtctca tcaggtttag gtattaaagc aatatcatca tcactaatat taagtttatc 153660 ttgtgctttt tctctagctt ttttatcagc tttttctact tgttctttta tatctttttc 153720 attaggcaat tttaaattca cttccttttc atttcagaaa taatatatgc ggatatgaca 153780 tataataaac tgtcatatcc gcataatctt tactatataa aagagttgtt cttctattta 153840 ttcaaatcat taactttatt tacctgaaaa tactggtata gcagatctca catcaatgtt 153900 gaattgatct ccataagctc tattaatagc ttcttgaaga tcagaatctc cttgtgaagg 153960 tccattatta ttacctggat tgataataat agtacttccg tttccattat taccacctgt 154020 accaggatta tatggatcat taggattaac aatgacatta ccattattat taccattagc 154080 tccattgttt ccattttgtc cattatttcc agtattgccg ttgctaccat tatttccatt 154140 tgcaccgtta ataatatctg ggttattttg taaattatct ttaatgattt tatcaatttc 154200 tttattaatt tctttgataa ttacattacc tttagaatca actaagtcac ctttattatt 154260 gatagttgtg ttattaaaga tattatcacc tttattaata gtagtgttat tacctttaaa 154320 tgacattttt ctaagctgat ctaacatctt agctgtattc ttatcaatat tacttgtatg 154380 cttagtaatt tcatctaaat ccatacgttt ttgcttatca actttcatag gtccattttt 154440 gtaagatact gtagaattgt tataattatt ggtaatatta taaatatttc ttacagtatt 154500 attatcgcct tgaattgttt gatgagtagt agaattgttg gttgtagttc ctggtgaagt 154560 atagttatta ttaactatag tagaattagt atttccacca ttattaatta cagtacttcc 154620 accagaagaa cttcctgatc cttgttgttg agattgattt ggcattgatg aagatgaccc 154680 atcttgacca tttgcaccag attgaccatc agaaccacta gatcctgatg aacctgaaga 154740 accagagtct cctgattcac catcttctcc atcagatcct gatgatccgg attcagattt 154800 cttcttaccg gcttcagatt taagcttttc ttgttgttct tggtctattt ttttggcttc 154860 ttcgtaatca ataccatata tttgagcgta acgtttcatt aaacggtcat ttaatgcttc 154920 ttgttcttct tcatccatac ggttatcgtc acgtccagta atggatccgt accaagtacc 154980 atttttgaaa ctatattctg aagctcctgg tgaatctcct gattctgaac tttcatcact 155040 tgagcttccg ctatcagaac ctccttcacc atatctcata taaccatcaa ttccccattt 155100 agggttttta tatttattag cactgttaat aacaacacca tcaacaccat tagcctctac 155160 ttgtttacct ccaccaatgt acattgtaac gtgttctata ttatcacata aaataatgtc 155220 acctggttta aggtctttgg ggcttttagc tttaattttc ttaaaaggcg tatctccatt 155280 ccagaatgaa tgagtagtgg cgttcttatc catatctaaa ccagctttta cataagctct 155340 agctatcaaa ctagaacagt caaaagaatt agctccttgt ctgttaggtt gtgaatattt 155400 tgcaccaacc tgtttcttag cccatgcaac agctttatca attttggctt tttgacttcc 155460 gccaccgcca ccgcctcttt gtataggtgg attaccttta attattcctg ttctacgtga 155520 gcttttgttt tttcctgatg tagatgaaac catgttagaa aatttactaa tatcatttgt 155580 atcagctata actgaaccgg ccccacctcc gccagctcct ccaccttttt tcttagtaga 155640 ttttttacca gaaccactga attgtttgat aaaagcatta ccagaagaaa tacgtgaccc 155700 taaagcagga acgccagctc tttcatattt acttacccaa gaagcagctg cctgttctac 155760 tgttttagta gttttaaggt gagataaggc agcactttct gatccactta attctttcca 155820 taaataatct aattgtaagt ctaaatcaga ccatttttta cctttttctt tagcatattt 155880 cattaaacct tgtctacgag tattatccca ttgagcaata ccaataccat aaccagaaat 155940 agcactatta gcttttgctt catcaaattt ggcatctcct tgaacacgat cagctttcat 156000 tccagattca tgtgcaaagt tacctaaaac accagcagtt tgttcatcag aaagtccttt 156060 atctttaagg aaattccaaa ttttctctgc accttcacct tcaattccgg ctgcatcact 156120 tcctgaagat gatgctgaac ttgatgaaga tgatccagag ccagccataa aaccagccat 156180 gatatcattc atcattcctc cgagcttgtc aaaccagtct ccaatagtgt taactacttc 156240 tccacctggt tcatttatat ctaatttaga ttttttcttt ttcttcttac ttagtagaga 156300 ataaaaagga gacatacgca tcatagtttc tgctaatttc ttaggagcct ttttaagttt 156360 actcataaga tttttaggca ttaatttatt catttgatga ccaattctac ccattactga 156420 taatggtgaa tttttcatag ctccgtctac atctttttta atgtcgtctc tagtttttcc 156480 tgctgattct tctacttgtt tcttagcatc tttgttagct ttatctgaca ttccattcat 156540 ttcagctatt tcttttttag ctctatcaga tgcttcactt tcaattcctt cttgatatga 156600 gcttaattct tctttactag cttcagtcat ttctttactc atatttccca tttcttcttc 156660 atgactagag aatttgtctt ttaaccatcc ccaaccagat ttaattaatc cagttcctcc 156720 ttgaagaagc atagaagtca taccagttaa attacttaag cctttaccgg ctaatgctaa 156780 aggagccatc attaacatag aagcaccacc gacaactttt ttaatcaacc caccaaagcc 156840 acttgatttt tcttccatag ccatatcagt ttgatctcca aagcttttag ccatacctgt 156900 agttttctga accatgttca tacctaaacc aaatgctggt tttacaattg atttatataa 156960 tcccattcca gctaatccta ataaaggagt agaagctaat aaaggattat ctttaataaa 157020 accgcctata attgaagatt tatctacaga accatccatt ttagtatcaa ctgaaggatc 157080 aactgcaaaa ttttctccac caggttgagt tgaatctaat ttctcttgtt cttttttagt 157140 tttagaagga tgatcattga atccaataat gctacctaat gttttaattg gatgttttaa 157200 tgattctata ggatgagtta ttgttctaat aatatctggt ccagctaatg ccaatgatgc 157260 aatttgtcca ataccaggta tagcatttac tccaacacga gcacctactt tagctcctgc 157320 tttaagtaat cctttaccta cagctttttt agcacctttt ccagcagcca ttttagcagc 157380 tctagcttta agttttcctt taagtctact acctgcacca gccattaaag caccactagc 157440 agcaaatttg ccagttaaag aaccacccat gctagttact ttaccaccta atttagtatt 157500 agataattta cctatttttt ctttaacaag atctttacct ttgtttttat atttatcaaa 157560 tttttctttg agatgtttat taccctcaat aaaatcttga gcttctccta ctttatctgc 157620 aaaatcttta tcatctgaat tgtcagaaga tttagcttgt ccattttcta aagtttgttc 157680 attaggaata atagtagatc tattatcttc atctttaata ttatcatttc ttgtattatc 157740 agattttcta ctttgatttg tattagaaga tgctgtagaa gtatttttat ttaaagtttg 157800 ctctctagga tctatttctc tagaaacatt atcattaggt tgattcacat cactaattat 157860 accacttgaa ttactgtcac tagaattact gttatatctt ttctcaggta ttttgctatt 157920 tattctagat acaatttgtt taatttcact tatatcttta ttaacgatat tgaagttaat 157980 attatcgtat actgcatctt tattagtgct aagaatacca cttccatttt cattatttaa 158040 tttagaagta atatttttag aagtaccttt tcttttattt tcatcattaa gagcatttat 158100 agaactacta gatagtttct tcttaatatc tttagattct ttatttaatt gcattctagt 158160 tttagttaaa ctagttttag cttctttatc attaaataat ttatctagga gaatattaaa 158220 tggatcattc gggtcatttg atttaacctg atcaagttca ttgcttttat taatattttt 158280 agaaataatt tctttaatct tagatgtagc tttatttttg ttatcttcat tactgaaaag 158340 atcaattccc atttcagaag ctatattttc aaattcttta gtaaaactag attccttgat 158400 agttttatta actttttctt ctatatcatc tttaattgac ttagaagttt taaatgaacc 158460 tgaatcatag tcataatgaa tttcttgccc atcttctgaa gttaaaccaa ctattttaga 158520 taaataacca ggtataactg tattaagtgt attatgagtt tctacatcaa aagcaacttt 158580 ctgatgtcta tcttttctgt tagcagttga tataccacca tttacactat caaatatttt 158640 atcaattaat ttacttttac ctgatttaac atcctcaaga agatcatctc ttcttttatc 158700 tctttttctt tgtttagtac catcgtcatt atctttacca aaaggaataa tttttttatt 158760 ggcaaattta ccaactgctt tttctatgaa agtattttca ttattaagaa aatcaaaagc 158820 tttaccttta gctacatcaa ctaaacctaa atttttaatc ccttgctttt tagaaccgat 158880 aacttcttta agcaattcag ttccttgttt tttaataaag tctttagctt tatctttgaa 158940 tccttcttct tgagatcctt ctaatatatt tgataaagtt atattagata ggaataaatc 159000 ttctaatgaa ttactatttt taatttcaga tatattctta attttagtat tatgtctaat 159060 agcattacta gtttgaatta aaccatttaa gttctggaac atactttctc taatactatc 159120 attagcttct ctcattaaat taagattatc aatcatagaa gtaaacccag tagtatttat 159180 ttgagaaaga ttagatacag aagaagttaa tagagctgta gatttagcag aagaaccgcc 159240 atcattaata actgttgtag aagatactat tttagatttg ttatcttctt ctccgtcaaa 159300 gtcatcaaat tcaaaatctc catctaaaga atcatctgtg tcagaatcca tatctgaaaa 159360 actatcatca aaaccaaaat cttcaaaatc accaccgata tccataccca tgttattgaa 159420 gtcttttagt gatcctttat cttggatagt ttctccagtt ttaaaggtat ttttagtaga 159480 ttctaaagct tctttagata aatctttagt agattcactt atcttttgta attgtttttt 159540 ctttttattc tttaattctt tgacagcttt taatggatta ttttgatcca tcatacgttt 159600 catgtcatta gacttcattt tatttaaatt tttgttaaat tcaatatcta tatattttct 159660 agaagattta gaggaggagt tatttctaaa ctccttctct atcttgctag tgttaaattt 159720 cttatctcta gccaattatt agttccacct cctgctatct atttcaattc ttctaataaa 159780 cggtctaatt ctttagtaga tgctaatgta tttttatcta tattagctaa cattcttact 159840 aaatcatctg aataccataa tttttcataa tcataagtat aaccagagtt accattttca 159900 attttagaat ttttatgatt gtttacaatt ttattataat ggttagttac tcggttttta 159960 ccttttataa attctttatt cacattttca ttattaatga cattactttg tccattttga 160020 taattgttat taactgtttt agtattttta ctaccttgat tgttaacagc attattacct 160080 ctattaatat tagaaaaacc actattagct aatgttggta attggaatac cggaggattt 160140 ccgatattct tattattagt tatttgagat cttgattctt gtggtttaga tggcgatgct 160200 gaagaatcag aactatctga agattcttca tctccagaat cttcacttcc agatcctgat 160260 gaacctgatc cggattcaga tttcttctta ccggcttcag attttttctt ttcttgttgt 160320 tcttgatcga tctttttagc ttcttcatag tcaataccgt atatctgagc ataacgtttc 160380 attaatctat catttaattc ttcttgctcg tcttcatcca tacggttatc atcacgacca 160440 gttattgaac cataccaagt accatttttg aaactatatt ctgaagctcc tggacctgat 160500 tcactatttc cttctttatc atcttcatca cttttagaag cagaagaact agatcctcct 160560 ccgccaatag tctctttaat tgtacttgct aaagctttct tacctttact attcggatga 160620 acacctaaac catcattttc aatcatatca gaactggctt tactattcca gtctattact 160680 tttgaatctg aactttcaat agctttatta gttgcttcaa taatatcaga aatatcagat 160740 ccttttctct tttcaggatc tacatacgta ttaacaaagt atacatctgc tttgtcatac 160800 atatcttcta tttctttaac attacctgta gttaatcctc cattagtacc taattgcact 160860 ataattgcat ttttatcttt attgtatttc tttttgttgg attctaatac atttttacca 160920 ttaggcgaag gacctccact tgaataagtt cttgaaggaa ctgcattaat ttgaatttta 160980 ctaactgatt ttcttatttc agaagcagct cctgcaccta tggagtcacc taccataaat 161040 actttattgt aggatttacc tccaccgcct ccaccagtta ccgttttagc tatttttcta 161100 atggcttcag gagtattact gaatggaaat ctatctttaa taaaattatc aactcgtttt 161160 ttaatcttct taatattgta tatatctgaa ttgtaaatct tagttttttc tttttctgcc 161220 ttttcttcag ttttcttctg attattttct aatttattta aaagagctct atcatttctt 161280 acttctttag ctctttgtct tttagcttct ttgacttctt gtgatttata accaccgtct 161340 accattttta cagtaggatc aaatgcagct ccaccttttt tacctttttt agattttcca 161400 gctttactac ctttgtcttc atcactaccg cctttagaac cttttaaagg agctttaatc 161460 caaggtgatg gatctacaga gtttttctcc atagcccaac cgcctggttt acctttattt 161520 atttggaagt gaaggtgacc tgaaccagca gtattagcac cagtgttacc tgagattgct 161580 ataacttgtc caattttaac tttatcgccc tttttaacta attgtttagt taaatgcata 161640 tacgtactat agatgttacc aggtgattta acttgaacaa tattacctcc acccggatcg 161700 gtgtttgatc taataactgt accttctacc atacatttaa ctttttgacc tggaagcata 161760 cctatatcaa taccatagtg ctttcctccg ttaaatgata aaccagaata gttaccatat 161820 ggttgccaaa tcgcagcact tggtattttt ttcatccaag caccaactgt gccatctggt 161880 atttgattaa tagaaccagg tacaattttc ttagtattca tatctacttc gccagcttca 161940 cctgaaactt caggttcacc gtctccacca gaatcgccac cactggaatt tttcatttta 162000 gacattgcaa caaccatttc ttccatttta actaagaaac gactgaacca atctccgatt 162060 tctcctttac catatttaga gaaatcaatt ccgcctttag ctatttgata caaactacct 162120 agaggtgtac tcatgaacat atctttttga atatcttctt cagcttttgg tcctgatttc 162180 attttattat cagtaattgt tttaaacata tctccaccaa ctttagctag tgggaacata 162240 ggagatgctc taaacattag tttagaagta cttaatatta atctacctaa acctgtttga 162300 tcttcagtat gtttttcttc tttactttta gcttcatctt ctattttatc accaggatgt 162360 tcaccaattc cgaagaaact acctaatgtt ttaattggat gttttaatga ttctatagga 162420 tgtttaatag ttttaatgat atcaggagcc cacatgctg caccaattac tggtccaaca 162480 aatggtatga atggtaaggc tgttttcaaa cctgctttta atgcaaattt tcctccagct 162540 ttcattgcac ctttaccaaa taatttattt ttagctttac ctatagcacc aaaagctttt 162600 cctccaagtt tcttagctcc accgaataaa cctttaccga tagatttagc tctgttaaaa 162660 cctttagaag caaatttact tattccttta gttgcagctg aagcattctt tttattaaat 162720 attttagata taccactttt agctactttt cctatagttt taccggcact taatcctttt 162780 ttaactaatc ctgcaccttt acctataacc attttaccta aagatttaac agaaggtaat 162840 ttatctttag caaattttcc aataccttta aatacattac ctattttttt aggagcacct 162900 ttaatacctc taaataattt tcctaatcca aattttccag ctatattttt aattccgcca 162960 cctattttac ctaacatgcc aggcatacta gtaaagaatt tacctattcc gcttggtaat 163020 aatttagata ataatttagg tccaaattta gcagctaaga atcctccagc acccaacatt 163080 gcagcgttac ctaagaatcc tccagcagat gctaagaatc ctttcttacc aggttctaga 163140 tcttttttac catttttacc tttcattaat gaacctaata cagctgcaga agttccagca 163200 aataaaactg gtcccatttt actaaaatca agcataccat tcatcatttt tttagcacca 163260 atggattttt cagcttctcc accttttcca aagtttatat tacctctaat ggattcagca 163320 atttcttttt tattggaacc tgttatttta gacataacat cttccccaga ttttcctgca 163380 tcggcagttg aaaggccttg tttcattctt tctaaagctc cagcatcttg agaatctttc 163440 atatcttttt taatagttgg atcattgcca aaagcagttt taactaaatc gattattgta 163500 ctcttagctt tcttttcttt ttcctctcta gttaaatcat ctatcgtttt gcttggttct 163560 ttagtgtaag catttttatt agcttcatta ttattaattg ataatttatt taaaccagga 163620 atattcttca ttaaatccat taatggatta ttatctataa tactagattg atttatattc 163680 tgataaggat attcatcatc ttgatctggt tgagtatttt cttgagttga attaactcta 163740 ctagatgcag gagaaaccat atctttaata gcacttgtag ggttttcttt gtattcttta 163800 gctttattaa ctgcattaga aagactattt aatttatcca ttacagaagc atgagcttca 163860 ttacttccat tatttccact tagaataggg aaatttttac ctttatctat gatactattg 163920 attgtattaa ctttattatt aataaattct ttattattat taatattatc attactgaaa 163980 ttattgtcta attttctttc tatttctaag aaaatatttt taatttcttc taaatcacta 164040 ttttcccagt taatattacc aaaatcttta atctgattaa tattatcatt attattagat 164100 ctagaataag tcgaattaga tttatttaaa ccttctattt cagtaaatgc cattattctt 164160 gaattatctt ttttatcaag tgtttttgaa atagatttct taatattgaa taaatcagta 164220 ttaaatttag ctgaattctt ttcaaacact tcagataatg actcagtatt aacatttata 164280 tttttctgat taactatttc tttaagttta gaagtttttt ggataggttt gtctatttta 164340 gttaattcag ctaaaacttc tttagttctt tcttcatcat tatctaattt agataataat 164400 tctttaccta aataagtatc tttaaaatta aataaagaat ctgatttaat cttatccaag 164460 tcttttttct tagccgaacc tcgattttcc caaacgcctt ttcggtaatt atagatacta 164520 cctaattcag cattatctgc taatccgcct gaacgacctt cttttttggc tatcaaatta 164580 ccttgaagtc tagataagaa gtctggtata actttattaa tagacgtatg agattccata 164640 tcaaattgaa caggagtatc ttttttacgt ttatttttta gagaaatacc tcctttacca 164700 tcacctaata actcttcttt aaattgatct aatctacctg aaagagcatt tcctaaatta 164760 gatatatact tattatcatt gccagttaat ctttctaaac ctttagtaag tttactatct 164820 tcatcaagat ttctattaat aagcatagaa cctatatttt gtggatcaaa tcttttattc 164880 aatctatta atatattttt attgtcgcct tcaggatcat aaccaccaat atcaccgtaa 164940 agaagtttat taaatgcaat tttagctcct tgagttgcag caaattcaat aggattttta 165000 gctacaccca tcagcattga tttaagttgg tctccggaca tcatacccat taataaattt 165060 tcaggattag ttttctcatc caaatatttt aataaactaa tattaccatt caatatagaa 165120 tgtaatttac tttgtttatt tcttttggta ttttcttcca ttattgtatt ttgatatata 165180 ccatcttgta ttgtacttaa atttgataaa gctgaatcta cgagactgtt agttgcttgc 165240 attgataaag aataattatt cagtgcaata tttgttccaa caaatcctct ttgatttatc 165300 tcagctaaat tattcattgc tactagaggt gaatttgtta ttttagattt ctttttatct 165360 gataaactaa caatttcaga tttagtccca tcaggattat caatatattc tgttactgat 165420 tcatattcag gtttttcatt agataatttt tcattactac ttgaaaaaag atcattttca 165480 ttagatttat tttttagtgt ttttaataaa tcattagtag aacctttaac ttcagaaaat 165540 ttctttaatc ttctttcatc attgttgaat aattttaaac ctgaatctcc cactatagca 165600 tctaatgatg gattagattt tataaacgca ttaaaaagaa tacgaccagt atttttagaa 165660 gcatttttaa tgacagttga tttattgtta ttttctaatt gtctaatatt ctttttattt 165720 ttattatttt tagccaaact tcaaattcac ccctaacatg attttcttaa tacatatatg 165780 tttctatcag attcatatag attaaattaa aagataaaaa aaaataaaat attcacccta 165840 acacaaataa tccaattaag gactaaatgt gttagggtga attaatatta tttattcttg 165900 actacatctt gtattttatt caatacacta tctaaatttt tagtataaac taaattagta 165960 aataatacat ctaataaaaa tactatcgtt ttatgagtga tataaaataa attattaact 166020 attttatctt gttcttcttc gctaatttct tctttatctt gatgatattt tctgttaggt 166080 aatgaacgtc tacttaatcc catatattca actaaatatt catttaattt cgttttaata 166140 tcatcaagtc tatcataatc actaatactc ttatcgttag ctaaaagaag agttttgtta 166200 taatcgatat tacttgtttg aagaaattta ttgtccatat atttacttaa taatgttgaa 166260 ttgatagata ttaagtaaag aataatatct aataattctt ttgatgcatt attaatatat 166320 tcaaactttt gagaataatt gtattcagga ttattagtaa tttgatttat ttcataatta 166380 aattcatgaa tttcttcaac tatttgaggt atgaatctat ctaccatttg atgtaattcc 166440 tcattaccaa aatcgtaacg agaaattaca tttacatgat ttatatacat agcacttata 166500 tctaattcaa tagattctct tttcttataa aaatgtttca ttgacaattc ctccatgttt 166560 ttaattggtc ttatctaaaa cgttttttgt attcttcttc atatttagca ttgacatctg 166620 aaactttaat atctttacca tcatctgttt taaagttatc tttatcaatt tcttcacctt 166680 taattacttc tttatcttca ttttctactt tagccaccat agcaatatga ggtggtacaa 166740 atgatgcttg tttaactgtt tccattttag cattatgaat acgaccttta attaatttac 166800 gagagaaatg tacatttttc atagttaatg ttttaccttt gactaatgca ttttctctaa 166860 gtgcatcaat ttcattaata atatcactta attctttttt agaatatcta ttatcttcta 166920 gatttgctac taagtcatta ataagttctt ctttagtata agatttctca ctgaattttt 166980 taacattttt ctttctacta gtcattttct ttttaccaac cttctgattt gatttagttt 167040 ttgtactttg tttcttttct tttaatactg ggttcttaac ttcttcttta gtctcttctt 167100 gcttagtttc tactttatct tcttcttgtt tagtttcttt ttgcttaatc tcttttgctt 167160 tctctggatt taaacctgaa gctgttacag ttactttatc ataagaactt tctgttggaa 167220 tatccttaag attaatttca acatctttaa gttcatctga attgatgaaa atttcttttt 167280 tatcataatt aatcttaata acatcatcat cttcaggaat taaaactaaa ttctttctgt 167340 catatttctc tggaatagtt tcgatatcaa atgtaattgt atctccttca tatccttgtt 167400 cttctgataa tttaatctta gctgactcta atacagttaa atcctctttt tcttttgtaa 167460 ctttctttct tgtaattgcc atatccaaat ctctccttat ataaaataat ttgaagctaa 167520 tattcttact aacttcatta aaataatata tatttatatt attaattgaa gtttataaat 167580 ttttattatt agagtttttc tatgatccag agtattaata tattttatta attaaaaata 167640 tattattattaa taatatttat attaatatta attattaaat ttattaattac tactaatat 167700 aagtaatata ttaatacaaa attttaaaaa tttataaata aaaattttat aaaatctgaa 167760 taaccaattt atattaatta aaaaatcaat gacgtttaaa aatataataa atttgattga 167820 ggtgtatta gataatgggt ttaaataaaa aacaagaaga aggattaaga ttagctaaag 167880 aatggtataa taatgatagt catagacctt ttgtattatc aggtattgct ggaagtggga 167940 agtcatttac aatgactaaa ataattgatt ctttaggctt acatgaagct aatgtttctt 168000 ttatagcata tacaggaatg gctgcaggcg tattagttaa aagaggtttg aacgctacta 168060 caatccatag aactatttat aatcatttta tggatgaaaa aactggtaaa gtgaatttta 168120 gattaaaaga tgaattaccg agagatatta aattaataat tatagacgaa gtttcaatgg 168180 ttcctatgaa gatgatagaa gaaattcaaa gttttggaat acctatacta tgtttaggag 168240 atccagcaca acttaaaagt ttatcaggaa gaaatgaatt attagataaa cctgatatat 168300 ttttagatga accagtaaga caatcattag ataatcctat acttgttgca gctaatttag 168360 ttcgtaatgg taaagattta gaatatggtt catatggaga taatgtacat gtaattactt 168420 cagatgaatt gactttagat atgtatcaga atgctgacca agttctaatg agttataata 168480 gaacagtgga tcaatttaat agattctata gaagtcaaat attaaatatt gatgttgaaa 168540 ataatccatt tcctaaagaa gatgaaaaaa ttatttgtct aaaaaataat tggtctaaag 168600 tagttaatga aggtaatata actcagtatt tgactaatgg tctgattggt aatataacta 168660 gatctggtaa aaagaaacct atgactaaat caactcagtt ggattttaaa cctaaaggtt 168720 ttgaaatgga aagatttagt agaatatatt acgatgattt aatctttgaa ggaactattg 168780 gagatcaaca agaactattt gattaagat tcaaagataa tgaaattaat aaaatattta 168840 agaaacgata tgtaactgaa atgtctgatt ttggtatgaa agtaaatcca tttaattttg 168900 catacggaat tactattcat aaatctcaag gttctgaatt tgataatgta atagtattta 168960 gtgaaaatat gagtaaagat agatttaagt cgttatatac agctattact cgtgctaaaa 169020 agaatttgat tgtagttcaa taatatgtat aaggatgata caagtggata ataataatgt 169080 aagtagtaaa atcaataaaa atcaattaca aacagcaatg aataatatgt ctaaaaatat 169140 aaatggtata ggtagaaagc tatcaggaca agataaaatt gatgagatta ataaacttaa 169200 aagagaaaat gaagaattac atcgttttct ctttaagatc tatcaagatg atgattttga 169260 tagaagagaa ttgaagaaaa ttatatttaa agatgtaaat aaaaaattta aataagggtg 169320 attaatttga attcagatat ccgaatagat agaagtggtc tttatataca atctaatgag 169380 aagcagatga agggacaaat taaaattata gaagaaaaca aaaaattaaa agattttatt 169440 attggtatta aaaataatgg tggttatgat gaaaaggaat taaataaaat agtaaatgaa 169500 attgttaagg agaatttaaa ataatgtcaa atgaaaaagt tattgctaaa gaattaacgt 169560 tagaccagaa aattaaaatg ttagaaccaa agatagatga agagacttat ttaagaccat 169620 taagtcaagt agatgaatct ttttataatg aggttattaa agatgaatta attgagaaaa 169680 ttaataatga agaccataaa tttgaaaata attttgatta tcatatattt aaaaacggac 169740 caatacaatt actaggtttc atttataaat ttgaatttaa tgaaaatgca gtaaacgtta 169800 aaaaagaaaa acctaatgaa ggtaatatct attttggaag ctttatatta aataataaaa 169860 ataaaaaaga tgattcaata tatttactta gagttgatag cagcttagtt gatttcagta 169920 tattagaaaa taaaaaatat aaagaatttg gcagaaactt atttaaatta attaaatagg 169980 agtgatataa atggataaag aaatcgaaga tctagcagga aaaataaata atctagaaat 170040 tgaccttaaa gggataaatt acagattatc taatgataaa caagttattg attttgaaat 170100 aaataaaatt aatgaatata ttaaattttt acatgaagaa aatcaaagca tcaaaaaaga 170160 aaatatgttg ttaaaagaag caatagtgtc tatttctaaa catacagaat ttaagaatga 170220 ttatataaat aaactgtcta aagaaattgt taaagaaaat tttaaataat aaagagatgt 170280 gattttattt tgaataatga aaaaagttta attaagcgta tggaagagtt agaagaacgt 170340 actagaatga atgaaattaa attaaatact atgaaagata attatcatta tataaatgat 170400 atcataggca cattaattaa tagaatagaa aattctaatc aaactaatga aaagaaattg 170460 gatgaagtaa gattagagtt agttcgtctt tctaacgaat taaattcaca ttctgaagta 170520 actaaaaagt atctaaagaa ttttatcaga gataatctta aataaaggaa tgaagtgcat 170580 gaagactatt aaaagaataa ttggctcaga agaatttatc aatacggtaa agaaaactat 170640 agctagaact aagaaagcag aagagaaatt ttatgattta aataatagag ttgataaagc 170700 tttatcttta gctagtagag ttgttgaaga taataaagaa aaagaaagac aaattaaaga 170760 gctaaaagaa gctttatcta aagaaaaaat taataacaga agcataaaat cccgatataa 170820 tagattatta tataaaaatg gagggaaata ataattatga actcaaatat taattttaat 170880 gataatggat catctatgga tgaactatat tcaagaatgc aacttagagc cgctaaacaa 170940 gtagaaaaag atatattggg agatactgaa aaagattccc tagaaaaaga attaaaagaa 171000 cttagagaac ttgttcttga agtagctaaa aagtatgatg ttaaagaaat aaaagaatat 171060 ctagttagaa aaaatatgaa atagtgttta agaaaagagt tgaataaaat tggttgaaaa 171120 tgatttagat atctttaaag caattgaaaa agcaactaat aatatcttag ataaaaatga 171180 aaaactaaaa agtgagaatt tagaacttaa agaattgata tagatattt ctaaagaata 171240 taatataaaa gataaaagaa taactgaaat aaaagttgat ctagcaaaaa ataagaggta 171300 atgacaaatt aatgtcatta cctcaattat actgctttta gtcatcatat ttatctttat 171360 attcataata actatcaaat tgaacttcta aacctgagaa agctgaaatg aatcccattc 171420 taccttccat attgatgttt tcaatatctt taaaatcaac atctggttta cgataattga 171480 aattcttatt tttatctata aatattctaa ttctattttc atttttaata atcttaatat 171540 acttgttatt aatgtctaat ggaacatgat tagttaaaaa taattgtttt tctgattcat 171600 cttggaatat ttctttaggt tttccaaata ctttatcaat ttcatagaaa ccagttttca 171660 ttatacggtc aggatctttc ataacatctt catcattcaa atcaaagtaa ggaacatccc 171720 aattttcttg ttgagaagct atccaaagca tataacctga atttagttga gtattataat 171780 caaatataat ccctgctcca ccagttttat ttttattaat tactttaaat gtcataatat 171840 aatttttagg gaatttgaaa ttttgactat acacatagtt caatgcgtca tcatcaaatt 171900 tagttgttcc atctatgaaa ctaatataac cataattacc taatgattgt ttagataaag 171960 ttttattata aaatccggta taagtttgag tttctacagg aaatgtacca tatgatctta 172020 atgcaactat cataggatta aagtatattc ctgatctact ctcatcatag aaataatcag 172080 aaccatctgg atttttaagt gaataattat actccaactc aacattatac caatcttctt 172140 tagttacgat aaatgtatta tcgaattctt catgactaat tccagctatt tcaaattcat 172200 ctaaactaac ttgaattatt tcatttggat caacgtcatc aacaaaattt gttaatttga 172260 cttctatttc cattttctta atatttttca tattgtacat catatgttta agatatgatt 172320 tttgaccttg agtattataa tttttattat ttgaagggaa tatattttct acttttttaa 172380 ctttacctgt atttgatgtt aatgtgatat cataaactaa cttagctgta ggatgattat 172440 tatctttaaa gttagttgaa tatcccatat taaacgcaaa gaaatcataa tttaataaac 172500 gtttaatatt cattctagga ttttcatttt catcatctaa agttatctta acaaatgatg 172560 cagaattttc atcttctttg tcagatttac ttaaaatatc tcctttaact tcatataaac 172620 cggtttcttg attaaaactt actgaagata atcttgttga ttcaagatta gaatgactta 172680 catcttcatc attagctttt cttaaatcaa atatagctgt gggtgcttta aattgatagt 172740 tctctgtagc attaattaca ttaaaacctt ttcggtctgt tatttttaat tagatgtac 172800 cattttgtaa aggtgcaaat aaatatttct ctcctggttt aaagtacatt ttaccttgaa 172860 atttacgtga aaaccctttt ttataaaata gatgtggtag agtttttaaa ccatcgttat 172920 taagtgtaaa tggttctact aaatctttat tatctgtatc aggtctatag aatttttgct 172980 catgaacttc atgtctttct cttagatatc tatcagaagt gatattttct aatttatctt 173040 caaaatcagt ttcaggtacg aatggtataa ttctaggatc attatatcct ggtgtaactc 173100 taccggattt ttcttcagta cttttcatca tatgtttaaa aataggttta ggattatttt 173160 cagtacctaa tatttcattt tcttcattaa taatcttatt taaatcatta atgacagtct 173220 ctgggaaaat ttttacagta tctgtattaa attgatccac tgtttgcata tcattaacaa 173280 aaagtaaaag ataccaaaga tcagtagttc catataattc attagataga tattcaggtc 173340 gatagtgata tgattttgat aagtcataat ctattaaatc tcttttaagt acattttcat 173400 atttttttag taatggtaaa ctaaagacag cttgtttttc aaataaatac cattctgata 173460 tattattaag taatatttta ttcgtcttgg agtattctat ttcatcagac atttcaggta 173520 catcatttct acccatattg ttatttccta cgtcacgaat aagcaaaatt atttcacttc 173580 cattcttatt ttgttataat aaatgcatgt taaagttcga atgagcatat taataaaaaa 173640 ctaaaaattt caactaatat tttaaatata tattatttta atgagattga gatggaatta 173700 atcttaatac tcaaaaaata aaaattttta attacaagga gagatttgga tatggcaaaa 173760 gtaaaatact cacaaacaaa attattggta agaggagcat tgatcaga tgaaattatc 173820 aacgtagttg gtgatggcgg aattggtaaa acacaaatga tgagagatat tgcagaagaa 173880 gataatatga acttcattac tatcgctgca aataacctta aagaagggga attatcttta 173940 ccaatgttat cacaaaaaga taatgaagtt atctatgctc caatggataa aattaagtta 174000 gctaatagtc tttttgagag atataaagag tatcaaagag aaggtggaaa acaatattca 174060 cgtaaagacc tttctttaaa atctgttgat gaattaaaag aaatttatgt gaaattgact 174120 ggtaaagatg ttgttgatta ttatgaggat actcatgaaa actatgttaa taaagtattt 174180 aacaaagcta gagttaaaaa tgttaaatat agtaaaaatg atttaatgaa aaaatcattt 174240 gatgaattaa atgaaatctt tgtagaatta actggtaaag aattaagaga taaaattggt 174300 aaaggtttct atatcaaaga aattttagaa gcagttccaa gaccttatac tctattattt 174360 attgacgaaa ttggacgtac agaccaacaa gtacaatcag agttaatgaa cttcttatta 174420 gaacgtcaag taaatggtta tcatttacca cctaacgtta agattgcatt agcacaaaac 174480 ccatcttcag acatgccagg atttgaagac tcagaatacg cagcaacttc tatggataac 174540 gcagtaagtt ctcgtattac atttgtacac atggttcctg atattgaaag ttgggtagac 174600 tttgctacta aatataaaga tggttcagaa aagcaaaata ttcatccatc tattgttgag 174660 ttcgtaactg aaaaagaaag tactgaatat ttattcagac ctcataaaga agctggtaaa 174720 gacttcaatg atactaaccc acgttcttgg gaaatgattt ctaatatgtt atatgtatta 174780 gaagaagatg atttatttaa attctctaat agtgaagaag agaaacgtaa gaagaaagat 174840 actttacaat tcttcactga aggtaaaatt aatagtgatt tagcaaactt atttgttaaa 174900 ttctatattg aaaaacaagc taaattacct cgtccaagtg atattttatt tgaatatgat 174960 aaaggtaaaa tggttcctcg taaagaatta gctaaacaac acattgaagc tattgaaagt 175020 caatcaacta ttagacaatt aacattgaaa acttcaatga ttaactatct taaaaataat 175080 cctgatttag ctgaagaaca agttattcaa attgctgtag aagctttatt attaggtaaa 175140 gttgaaacta atgctacacc aattagatta atttctagac tttcagaatc tactgaagag 175200 tcagaccaag aattatatga gaaattcact gataatgaat tatacagtga taaagcattt 175260 gcattatacg aacaaatggt aggaagctta ggataacaat tatagataat ggagattatt 175320 agtctccatt atcttcattt atttttttat aattaggaga gtgaatttga taatgaatga 175380 taatagaaca attaaagtaa ttagaaaaga aatattagac gaagtacaag aatcgattgt 175440 aaatgataga cagttagata aaaagaaatt aacaaagctt ggagaagaat taattgaaaa 175500 tagtattttt gtgttgtata cttctgatgt tgatatttat ggagtaatgt taatgactgt 175560 agaaaagatc attgacattg aaattccaga accaactttc tcagtatttg atgaagaaaa 175620 aggttataag attggtatta atccagtgtt attagccact atggttgata aagatgaaga 175680 aatagtttct atgttcctac atgaagttat ccatgtagct catggacatt taattgaatt 175740 tagaatgtta agaaataaag aagattctca attaaaaatg ttaagtcact taggaatgga 175800 tttatcagta tttgaaattg aagaagactt ccaattaggt aaacgtgaag ctaatacaag 175860 taaaaaagtt ttacctgaaa ttgcacctaa tgtagataag attgaaaagt atattcaaga 175920 taaatttaat aaaacaaatt ttaaattaaa tcataatgat gcttctcact attatattaa 175980 acaattagta gatatctaca aagaaaataa tgaagaagat atgtttgatt ctatgggtga 176040 atctatgcaa aatatgattc aagaatcttc agaaaaacag aatgaacgtg atgaagattc 176100 attgaatgaa gaaaatgaaa tgttgaaaga catgttagaa gatttaaaag acattgaaga 176160 taaaaatgat ttatctagta aattagaaga taataaacta gaagaaaaca aagttgatga 176220 ttttgaaaat aaagctcaag attatatgaa taaattagat gaaatgaatc aaaatgatga 176280 agagaatagt aatgatactc aaaatcagaa aaatatagaa gagaaaatga atgatttact 176340 agattcaatg agaaataata cttcagataa taaatttaat agtaaagata ataatgattt 176400 atctgataaa atacaagaaa tgaaatcaga tatattaaat caaatgattc agaataatat 176460 gcaacagggt tctcaaggta tgcaaggtga agatagtgga atgcaagatg gacaaaatgt 176520 ttctgatatg ggaagtaaca tgactatgtc atcttcttta gatggaaatt ctaaatatgc 176580 agataaattt gattccaatc ctcttgaagg agatgctaca gaggaaagaa tgaaagacca 176640 attgtatgat ttattagaaa gtgctagtag taatagtcgt ggtgatacac ctaatcatat 176700 taaagaacaa attgaaattc taaaacgtaa acctaagatt aaatggcaag attatcttaa 176760 agctaaagta ggtaaaaaaac gttcttctag tacgaaaact attttaagaa gaaatagaag 176820 acaaccttat cgtagtgatg tacgtggaac tttacctggt agaaaattag gtaaagtatt 176880 tgcggctatt gacacttcag gttcaatggg tagaaatgaa attgaagaaa ttattgctga 176940 attgtattat attagtagtg atatgaaaat tgatttagtt ttattattct tctcaactgg 177000 tgttgaagaa gtagttgaag taaacagacc aaatcaattt aatgattatg taatgggtcg 177060 tggcggaact tacttcagtt ctgtatttga tttcttaaat gaaactgata acaaacgtaa 177120 atattcagta tcaaaagatg atacgctatt attcttctca gatggttttg gagaacctga 177180 ggtggaatac ggtgtattaa ctgatgttgt ttgggttatt actgaagatg aaaataatct 177240 ttcagttaga gatccaaaag gtaaagtact aaaattagaa atagataata aaagataatt 177300 caaattacgt caatggatat taatttatcc attgacgttt atatttaaaa ttttttactt 177360 aaaggagatt aaacaatgtt aaaaaagact acagaaaatg aattagaaaa gttattcaat 177420 gtcactattt ataatgaaga attttctaat ttaaaaccta tgtataatag aaaagatact 177480 gaaactagaa ctaaattaaa tgacaatcaa aattctagag tgtatgagaa tttaataaat 177540 ttcattaatt attctaaagc aggaatgaca cacatgtttt taactcgttc taataaatat 177600 agagataaat atattgattt tctaagaaat agacttggta aggaagattt attagatgag 177660 gttgaatttg aatatacaga tagatatttc agatctttca tatataatat agatataatt 177720 agaagaagtg aatatcaaac acatcaatct atagaaaatg actctaaatt agaagattca 177780 ttcttattaa gaaatggaaa tacaaatata gatagcttta aaacggataa tggtttatct 177840 atagaatttt tagataaaga tgtaaagaaa gattttttag ataagaacaa acaaattagt 177900 ttagaatctt tgctagctat cgatacgatg gtgtctaatt cattaagaaa gaaatggtta 177960 aaatcaattg aaaaagaaga attacctgat atgaatatta tatttaaaga agttccagaa 178020 gtagtaatta tactagcaaa cagtatatat gaaagatcaa atttcaaatt atcatatgta 178080 gatagaagtg ttattaatat acacgcagac gtttcagatg ttttggaatc aatactaact 178140 ttaacttcta attttaatta taaattaata ttagatttaa tagatgaaga tacttaagt 178200 aaaaatttaa atcatttcaa agcttctgaa ttttctttat ctgacaataa tgacattgat 178260 aatatattta gtataatcgg aattattaaa aaacaaacgg acgttattaa taaatttata 178320 gaaaaaagca aatcagataa tctagaagac aatattaatt taataattaa agaaaatgaa 178380 atagatgatg actttggaga aatattaaaa gtttatattg atagtgtatt atctaaattt 178440 agagaatata ttgaagatga taccaatata ttaaaagatt catctaaggt tttaataggt 178500 gaaaatctat ttggtttctt tatgaaatta gatgatctcg aaattttaat gattagaaat 178560 atatacagag ttttagatag taatgtatat aatcctgtaa tcagagatgt taaagaatca 178620 caagaaaaag ttatgaatgg aatagtagat tattttaaaa ataatactaa aaaattatct 178680 ttagatttat ctaatatcga tataagtaga ttgaaagata gttctttcac attattaaac 178740 gatttcataa caaatggaga agtaagtaat cttcgtatga aacctaatga agctaatata 178800 gagtatttct ataaattaag tgtggataaa gaattaaacc gtgacatatt aaatagtaat 178860 atacaatata tgaaacagga attattaaaa ggttttaatg atgattctaa aatgacttcg 178920 aatgctatta ttgaatttga taattttaat attaattttg ctgtaataga aaataattca 178980 tataataatg aaatagaaat aatgatgcaa ggagttactt ttaagaaaaa attaactgat 179040 gaggatattg ctactatctt tttatattca cataaagaag ttagtatata tcaagacaaa 179100 aaattagtta tcatggatag aaattatttc tctagaagag gtataaataa atttataaat 179160 aatatgaata atgtcttcac tgatttagat ggagaaagtt tatctaaata tatgtcttta 179220 atttataatt tattatcttt atcagataat tcttttgagg aagataaagc aatttataat 179280 actctatatt acaataaatt tgaatatatt aataaagaaa atgagttaaa agttgatagt 179340 tatattaata tgattaataa taaagatgta acagatgatt ttaaaaagaa atttaaaaag 179400 gtaagatcta agtatttagt ttctagaata tttatttaaa tatattattat ataattgagt 179460 tgataattga acttatcaac tcaatttaat ttttaattaa taggagatga aatggatatg 179520 agtaaagcaa taaaagattt atttatcaat tacaatatat cttatattga agttaatgaa 179580 gatcatgaac ttaatgaaat tgataaagaa gaattattaa aaatattaga ttttgatatt 179640 aaatttgaaa aggaagaaat tttaataagt gataatatta aaataaataa ttttaacggt 179700 aataagttaa taaattttgt atttaattat tactatacag ataatgaatc actaaaagta 179760 tttttaaaag acgttatcaa agatattatt atgtatggat ataaagaaga tagaaaaata 179820 agtctaaata taaatcaatt acctttagta ttttatataa ataaattttg taaagataat 179880 gacattaaaa atattaaatt cttttatact tttaaaaatt cttatgggaa tttttcattt 179940 ggtttattaa aagaagaaca tctagatgaa tttattgatg atatagaaga aataagcaat 180000 aataagttct tcaatttaaa tagagaattt tagatacta aattattgat taatggagat 180060 aaaaagaaat ttatgaagct aatatctagt ttaatagatt tggatatgtc gcataagagt 180120 aatatattta aattaacaat gataaattat ttttataaat tattcaatat tcatattaat 180180 agtaaagaag atttagagta tgcagatgaa ttaatgaagt ctaaaataga tagcgttaaa 180240 tatgatgaat ttaataaata ctatatattt gaaagatcca taattggtat agatacatta 180300 tatgaaaatg aactcctagg atacaataca agaataaacc ataattattt tactgataaa 180360 atacaaaaag ttgaggatga agataaagtt aaacatcttt caaaaatcag tttctttaaa 180420 tcaatagatg acatttataa agaagcatta ttcttgttat cctttgaaac agccaatgaa 180480 tatacagaca ttgcagttaa agaagtatta agattaattg aaaataattt tacagaaaat 180540 cagaaaaaac aatttgttaa agcatatatg agtatcaaag atagttcatt taacgtttca 180600 aatgataaat ataatcaaac atctacactt gttaaaatgt ctaaaggaaa attaaagaaa 180660 ttaattatga atgaaacagt taaaaagaca tttatttaaa ggagaatccg cttatgttag 180720 ttaaagaaga aaaattaaaa aatagaaatg atattagaat agaccatatt ataagtatta 180780 atttagatga tccttctgca cttaatatgg tttcatttca attattaata gaaagtaata 180840 ttctgagttg ttatattaat aacaacttgg atactacttt atttaactaaa aaagaattag 180900 ataaatataa taaattcata gattttgcta ttgataattt tgaatcaaat ggattattta 180960 taaataaaaa accggatgaa tttctaactg gtttaataag aaaagcttct atttctagat 181020 tattaaaat gattgatcca attgataaaa ctatcagtaa tgaaaattta tttatcacta 181080 gattaaaaaa tattagacat aatataaatg aaacagatag taaagattta gcttatttct 181140 tatacaccaa ctttagagaa gatgttccgt tagatagatt aaaaggttta atgtccaatc 181200 cacatttaac atcattattt gagtatttaa tgaatggcaa tttaataatg gagattgacg 181260 agcaattatt aaataaatgg attatgttta ttgattatga aatagatgat attaaaggac 181320 ctatttatca tagattaaga catagtttag ttaatgtaat taataagtat aataatatac 181380 aagaagctaa aggttattta gggtatgaaa gattagaatt agaataaact taaaaagttt 181440 agtgagaagg gaaattttga atgaaaaaat ttagagatga attaataaat cactatacaa 181500 atttattgag attcaacgat gattcttttt attatagatt aaaaattaat tatttgaatt 181560 tcgatttctc taaagatgta aatttaagaa aaaataatgt gtttaaatta aattataaaa 181620 tcagcttttt cctatatttt aaaattttaa taaaagattt tatttcaaat aatttagatg 181680 aaaatggtgt atcattatta ttttcagata gtgttaataa taataatttt atttctacat 181740 tatttgttaa aaataattct gatattgaat tgaaactaga tttgggtgcg tattatgaac 181800 tagatgaaac taaaatagtt ctaatagatt taaatgaaga gtttaatata gaatattcag 181860 atgatagtat tataattcat acagatgaag ataattttga aaatgtagtt tattctattc 181920 taaacaaaat caaattcgtc ttagaaggaa atatatatgc atttagcata tctttatttg 181980 gcaatggaaa aataggagat agtaatatat tttatttaga agagattgaa aatatattta 182040 actctagaaa aaatagtata attgaagagc tttctgaaag tgaagttaaa aaatataaaa 182100 tcaaagaagg gttcaaatag taatgggtga tattaaattt aatgaagaat atatgtcagt 182160 taaaatttat aagttaatta atttgtttga gtttcaacaa acaactcgta aaagagcatt 182220 ttcaaaccat aattctgaaa gtgatgaaaa tgagcttaat atgtatatag gtaaaaatga 182280 caataaaaat atgattgaca tttttactag ttctttcttt ttatacaatc aatttaaaga 182340 tgtttgcagt ttagtattta acaatggtaa tactattatt gcagaaattg agatattaaa 182400 taaaaataaa ttgtcaattg aaattaattc agaaatctta attgttgata gtgaaattaa 182460 aaatttcatt atcaaaaatg attttagtgt aggagatggc ttcttaggct taattattga 182520 aaatgataaa gaaaaaattc ttaaattatt tttagaatca ttgtctgata gttatttttg 182580 gataaacaag aaaagaagtt taaatatatc tgattctaaa aaaattaaat ttaaaaaata 182640 tttagaagat ttatataaaa tgaaagattt ttatagtaaa gaaatcactg aaaaagaata 182700 taaagaaaat atagtaaaag ataatttcaa ataatataat cccaatactt attaatgtaa 182760 ttaacaaatt taaaagatta aagattattt agattacgaa agattagaac tggagtgata 182820 ttttaatgga agagatttat cttgataaaa gatttgatag tgaatatttt aaaataaaaa 182880 ctagagatat gataaactct gtaaaattta ctaaagaacc aaactttgat ttaattataa 182940 ataaccgtaa agaagaaaaa attttatata ctaaaaatga cagtattaga aatctattta 183000 ttgaatcttt tatcttgtat ttaaataata ttacagacgt ttatacattt agtatatcaa 183060 tcagtaatat taagttaatt tttagtttaa gatacaatca tacgaataaa gataccaaat 183120 ttttaattta tataatagaa aatgataaat ttaattatga aaaagatgta tctgaattag 183180 aaaaaatatt aaatgacata tcttctttag taaataaaga atactatata tctaaaggta 183240 gttttataat agactattta gatatagaaa aaattgataa gatattgtat tacattaata 183300 aattagatga tcttcgtata atgttagatg attcagaaaa agaaggaaaa tcgtatttaa 183360 gttacaactc ttttcttaaa gaactttatt taaaaagaaa cttatattct aaaagtatta 183420 ctaaaaagga atatactgat aatttagtta aagaaaattt taaataatat aatcccaata 183480 cctattacat caataggtat tgggataaat ttaaattatt ttttatttca tgctgtctaa 183540 ttcagctaat tttaatttag ctttagttgc atatttttga cgaattatgt cacgccattt 183600 tttacgagca cgagcagctt tttgatattt aaagtaaatt ggatcttgag cttctttagc 183660 tgcaactaat gctaattggt ttaatctacg tttacgttta gtacgttcat ctaaacgcat 183720 gatattttgt tcacgtaaaa gagcttcatc agttgcttgc ataatttgct cttctagtgg 183780 agtaatgtta tttttcataa tggaagatct tcctttcaat tatttttatt attcattata 183840 atgattataa gaaatatgtt ttatttaaga aatatgaaaa aattattgaa ccataataac 183900 ttatcttata taagtatgaa tctataagga gatgagaatt tatttatgtc taatcaagat 183960 aataaatatg aacgtaaaag agctataaca ggatatttag aaaatttaat caaattaatt 184020 aaaataagaa aacctgatat tgataatgaa aagttaatta atacttgtag agagtatatt 184080 aaaaaacatg tagatccagc tttaatagaa atatctggac aaaaaatgaa tgtggataca 184140 actttaagac aaattataga taataattta attgtaactg gttctggttc tatttatcag 184200 cctcaatcac aaagaaaaaa tttaaatgca gacatgttaa aagactttat agattctcgt 184260 aaagtagcta aacataatat gtttatatat aaaggtaaag atgatgtttt acatgataaa 184320 tatatgaacg aacaaaaaac aattaagatc ttggctaaca gttattacgg tgctatgatt 184380 caaaagaata gtacattcta tgatgctaat tcaggtccag caactactta tagcggtgtt 184440 gatattgtaa ctacttcagc aatagcttta gaaagattta taggtggaaa aatattcttt 184500 atgaaaattg atgaaatata tcattatata ttaagaataa ttaatgaaaa atatgaagat 184560 catgatatta agataaaatc aattccgact gataaagaaa ttttagaagg tttagtttct 184620 aatgttgaag aagattatag tgaagaagaa tatcttaaat tagaagaagt atttagtaaa 184680 ttaagtcaag aagataaaaa taaggtatat ttcaaaaata acttatttgg tttaattgat 184740 catactgata tatttgagaa taaaattagt aaaatgactg gtagagaaga tttcttagat 184800 ccaaacgaac cacctgaaga tatgattcca ttattagatg aattatttga aatattaaaa 184860 gattgggtta tatacaacta tcaagattat aatagaatgt atagaatgaa ttacaagaaa 184920 cgtagaagtg ttctcacaat tgacacagat tcaaatttcg tacacttaga tccattatac 184980 gaaaaaatga aatcattaaa acctgaagat tttcctctag cagaaaatgg tttagaagat 185040 aaattagaag aacgtgtagg taatatatct attattaact atcaaataac taagttatta 185100 gaattatctt actatggatt ctgtaaggat gtaggattag aagaagaaca tttaggctta 185160 atatcaatga aaaatgaatt tttacttgat aaacaattaa caacagataa aaagaaaact 185220 tatgcatcat cagtaattca acaagaaggt aatttaattc aacctccaga tttagatgtt 185280 aaaggtatgg ctattagaaa agttaatact aataaacgta ttagagaatt atttactgaa 185340 atattacaaa aagatatttt agaaaataaa actggtgtag atcgtattaa gataatacgt 185400 aaatttaaag atattgaaga aatgattaag aaatcattag ataatggaga aatcgaattc 185460 ttaaaaccat ttaaagctaa taatgctgaa gtttataaag atccttattc tcaaatggct 185520 tatagagctg ctttagcatg gaatataatg ttcccagaaa aggaaatagc actacctgct 185580 aagatattag cagttaaatt aaatattagt acatttggtg atattaagaa taaaataact 185640 gatgaagata ctttaaatag atttagagaa gtatttaaga atgaaagttt agttaaaaat 185700 ggtttaaatg taattgcagt cgaaggtaat acaattcctg aagagtttag accttttatt 185760 gactatgata gtatgattga agatcatatt aaaccaggta aagatattat tgaatctata 185820 ggagttagag tattggaatc ttcaaatagc tcatctgtat ctaatatgat taaattctaa 185880 ataattgaat gaggtattta ttatggaaaa atactataaa tttaatttat ttgagtacat 185940 actgaaaaat attggtatgc attcagatga atatgaaaat ttgataagta atataaataa 186000 aaattttaca tctttatatt tttatgacta tgagattaat aatagtgata tagataaatt 186060 gatatatgat aatattcaaa aacaattaat tgatgatagc tattttttat ttgaaatcaa 186120 taaagaagaa agattattag ttgattttga aaataacttt ttatatgata aatataatga 186180 gaaaatagga atggtttctt taaatagaat tacttctttt gagaataaat atagagattt 186240 aatatttatg gaaaaagaag atataaaata tgaaaattta attgatatgg ggtttaatat 186300 tgtacctact tttgaaattt ctactgtatg taaaaataaa ataaataatt ttagttactt 186360 tggttttgat attaaagata ataaaaataa gctattaatt gaatgtgatg aaaaagaatt 186420 caagataaat aaagttaaga ataattttat ataaatatta aaataaattt aataaggatt 186480 atgaataagg agactttgaa ttttatgtat aaagaagatg aaatgaatac aggtcatata 186540 gttgctgatt gtgatgaagt tttagtaaat atttccccta agatagttca gttaatgcat 186600 gaagatttg attattacaa tcaattcttc agactatctc cagagtataa ttacagtact 186660 cattacaata cagttcttaa tcgtcctgaa tattatattg accaatggtt agtaagaaaa 186720 gatgtttatg aaagattttc tgaagatgaa gttaatgaag ctagaaatag gttacaaaat 186780 gaaattatat ttaaaaaaga tttatacgat acattagaac caacaaattt agctaaaagt 186840 ttatcatata caatcaatac acctttaatg aatagattat caattgtaac taaaacttct 186900 gataataact taaaatctaa agagaaattt ttgaaaactt tatttagagg aagtatggaa 186960 aaggttgata tttattatct tgaatcagat gaaaagaaat cagatgtaat taatacatta 187020 ggttatgtta ctagaatata tgaggatgaa gttagtaata ttaaagacat tattatgaat 187080 tgtgataatg ttatgcaaac tggtatcgat attccttcat taggatataa ccaaaaatta 187140 gatgaagcaa ctattatgaa agctaaagaa aaagaaatag acttaaatta ttttagttat 187200 atgagtaata gtttagttaa ttaataatta ttgccatgtt aagtttatag cttaacatgg 187260 cttttatata tttatttttt ttttataaaa taagattgga agtgaaatgt tagatgaaaa 187320 tagatatgat caacgttgat caaattatta cagcctatga agctaaagaa gttaccaatc 187380 ctattttctt tgattcagga actttaccta aagaagacgg tttattctca tatgaaatat 187440 ttggtttaat aggtactgat gaaagaaaga acaatgtggg gtggattaat ttaggtggta 187500 aatacttaaa tcctgtagcg tataaagcta tgaaagaatt agataagaat atagatttat 187560 gtattcaagg atctgattac tttaaaattg aaaaaggaca attagttcca gatgaaaatg 187620 gtgaaactgg attaaatttc ctatacgata attatgaaaa tcttaaattt agaaaaaatg 187680 attctcgtat ccgaaatgaa aaaattgata tgcttaaaaa tactcctaaa gatagaatat 187740 ttacagataa atggcttgta atacctgctt tctatcgtga ctttaaccct aatgaaactt 187800 caggagaaat tcaagatact gaagaaataa atgatatgta tgcgagtatt ttaagatctg 187860 tagattcaat tagttttaac tcatttgatt ttgtagctaa tacgactaaa tataatattc 187920 aaaataaatt atttgaaata tacgttaaat taacttcagg tgaactatca ggtaaaactg 187980 gtatgatgca aagaaatatt ttaggtaaga cagtagataa tagtactcgt tcagttattt 188040 catcacctaa aatcaattca aataaatgga atgaaatgca aattgaattc ggtcaattag 188100 gtgttccatt aactcaatta gtaacattgt tcttaccttt ctttagtaaa tatattatag 188160 actttattga aattcataaa gatgctttcc aaactgctac tggaactgat gaaaaggaat 188220 taacattaga agaagtatat gaacaatttg atgataaatc tattaagaat atgttagaat 188280 actttattaa agaccctaat gaaagattta gtcctatata tgtaaatgat agacaaggta 188340 aacgtcataa agttaaatta tttgaaaata ctttaggtag aacttttact gtaattgatt 188400 tactttatat agctgctaca gaaatatgtg aagataagta tgtggtttat tcaagatatc 188460 cgattgaaaa tttcttgaat gtggctcctg ctaaaattaa aatactaact acagttgata 188520 caattccaga aattacttta gatgatattg tacttaaaga ttatcctaaa gttgttcatg 188580 aatatcctgt tgatgaagat gtatttatag atactgctat tatacacaac agttatgctg 188640 gagcacttgg agcagacttt gatggtgaca tgatctctat aagatctcta tggacagtag 188700 aagctaataa agaagctaat aaacttctta ataagaaaac taactatcta aactacactg 188760 gtaattcagt acgtaattta ggtaatgaat cagttcaagc tttatattct ttaactaaag 188820 aataactata tattataatt atagtata ggaggttatt tttatgaatg atagaacaaa 188880 gaaatttaaa gaaaaattag cagaaagaca tccagataga tatgaattac tgtctgaata 188940 tgagggttct aactccctta tcaaatacaa atgtttgaga tgtaataata tttatacaag 189000 acatgctgga aatatataca aaaagaatgc taaatgtaaa ggatgtcatg tcaaaaaata 189060 tgatactgaa tggtttaaag aaaaattatt taaaaaaatg gatattaatg aatattcttt 189120 gttatctgaa tataaagata caaaggaaaa agtaaaaatg aaacacaata aatgtggtaa 189180 aatatttgaa gctacaccta atagactatt atctggagac aaatgtcctc attgtgctgg 189240 taatattaaa aaaaccatag atgacatatt tgaaaatttt aaaagtaaaa tgaataatgg 189300 tgatgattat gagttaatta aagatgatct atataatgaa tatgctaata tagattcatt 189360 tgtccacata agacataaaa aatgtaataa catttttaaa aaaagagcta gatatatgag 189420 tagaacaaaa ccttctaaat gtcctcattg tgccggtaat attcaaaaaa caaatgaaga 189480 tttttcttca tttgtttcaa atattactaa tggtgaatat gaattaatta gcgaatatgt 189540 aaatacacat gaaaatgtaa aaatgaaaca taataaatgt ggaaatgtat atttgattag 189600 acctacaaac tttatatcac ataatcatag atgtcctaaa tgttcatcct ctagaatgtt 189660 ttcaaataaa gaaaaagaag ttttagattt tataaaatct ttttataaag gtgaaatcgt 189720 agagaatgaa agaaaattat taaaaaataa taaagaaata gacatttatt taccagaatt 189780 aaaaattgct atagaattta atggtcttta ttggcattct gaagctagac ttaataatgc 189840 aaaaaaatat cattatgaaa aaatgaaaga gtgtgaagaa aaaaatataa gattaataac 189900 attatttgaa aatgaatggg atttcaaaaa agatatagtc aaaagtaaaa taaaacatat 189960 tttgggttat aataactcta aaaagatata tgctagagat tgttacatta aaactttaga 190020 taatgaaact aaaaattctt ttttagaaaa taatcacata caaggaaaag atataagtaa 190080 aataaggtta ggtctgtttg gaaaaaatga tgaaaagtta tattcagtta tgacttttgg 190140 aaaaatgaga agatctcttg gtaataaagt ttcaagagat ggagaatatg aattgattag 190200 atttgcatcc gatatagatt atttagtaat tggtggattt tcaaaaattc taaaatattt 190260 cttaaataac tatgaagtat ctaaaataaa aacttatgca gatcttagat ggtcaaataa 190320 aaataataat gtatatgaat catactttca tctatcacac ttatcaaaac ctagttattt 190380 ttatacacat tcaaatagta agatagaaaa aaataaatat gtaaataggt attcaatgcg 190440 taaacatttg ctaaaagata aattcccaaa cagctacaaa gatgatttaa ctgaaagaga 190500 aatattagct aaagaaaact atttcagagt atgggattgt ggaaatttag tatttgaata 190560 ttgtaaagaa taatttaaaa aactgaggta acggacaatt atagttcgtt acctctatta 190620 tattgcaaaa atgtatctaa tgatatttta aatatatatt ataattatga agttgataat 190680 tattaatcaa ctaatttaaa taaaaggatg atttaatatg aatgaaatta aaataatgga 190740 tactgaacta ctacaggaag ctgtagaagg aaaagagaat aacggcggag gttacgaaca 190800 tactcgtacc gttttcgaat tccaaggaaa acaaggagtt ttcgaagaca cttcttgtgg 190860 tgatttcggt agcagattct tcatggaatg ggatggaaaa atggctatgt ggggaagtat 190920 gattgatgaa gaactcgaat acagtgaatt cgatgaacaa gaacaatcag aacttctaaa 190980 gcattttaga gttcctgttt ttgaagaaac aatctaggac attaatgtcc tagatttctt 191040 ttattttttt ttttctaaaa atattctatt ttatgattaa atatatatta taaaaataga 191100 tgcaattaaa tatattgaaa gatgttgttt tatatgtaaa gttttagaag aatctaataa 191160 gggagctgaa atagataatg atatattaca aaaataaagt aaatggtgaa atatacgaag 191220 ttaatgatat tcatagaaaa gatgatgctt tttattatgt gtttggtaat gaatttaaaa 191280 aagaaagaat aggattatat gaatcagtgg gtaaaaaaat tgatttatta gataaagata 191340 aaggacataa agaattaaac ttccaattaa attatgactc atctagatta tttttagtta 191400 cacatatgaa atatgataat aataatcctt ttgcacctaa agcagtagat ttaaagaatc 191460 aaaattttgt cgcatccgat tcttcagaag atctttacta tatattatat aaaagaatgt 191520 gtaatgcaat agatatacct ttattaaatt ataatgtatt attaaaagaa tttaattttg 191580 ataatgaaga tatatttaaa ataatatcag aagattgtaa agaagtaaga gattttaaag 191640 ttagaaatct ttttaaataa aaggagaaat tttaaatgga aaatattaaa ttgtataaaa 191700 atctagaaaa tggtgataaa tttactttat ctaaagatga aattaataat ggtagatttc 191760 tttataaagt catgaaacaa ataaaaagta atttttatcc atattataat tatgaagacc 191820 aacccattac aaccaatgga aactcttatt taattaataa acaactgaat ttccattttt 191880 atacacattc tgatattatt ataaatttta aaaatttaat tggaatagat gaagatataa 191940 taattaagag taatgaaaat aaagaaagaa atatttcatc ttcaattgtt tgtttctctg 192000 attctaatac aaataatgat agaatttatg aaaatatatt tcaaattgtt ttgaatacaa 192060 aaaaggctaa gaaaataaat cgtatgctag ataaatataa aagcgataaa tatgaaatat 192120 cttcttatac aatggataaa aatgaagtac attttaaagt tagtttcaaa caagattatt 192180 tgtctgataa gaataatgac gtttatgatt ctctagatga attgatatat tatatattaa 192240 agggccttaa aattaagatt gacaattcgt atatgtattt tatggattat ctaagatgga 192300 atttggaatt tattgctgaa gaaattactg atgaggacga aattaaaaaa tacttaatta 192360 aagaaaaatt taaataagga agtgtaaatg gatatgatat attacaaaaa taaagtaaat 192420 ggtgaaatat atgaagttaa taatattcat agaaaagatg atgcatttta ttatgtattc 192480 aataatgaat ttaaaaaaga gaattcgtct ttttataaat cttatggtaa aaagattgat 192540 ttatatgatg aagacgtagg aagtataaaa ttggagtttt tcttaattta tgattttatt 192600 aatcttcatt taactacaca cttttcttgg gattttaata atattccttt tatacctaaa 192660 aatatagaat taacaaatca aaatcttgtc atatcagact cttcaattga tctttattat 192720 ttattctata aaagaatatg tgatgtgata gatataaata tggcacatta taatattcca 192780 ttaggaaaat ttaattttga taatggagat atatttgaaa taatttcaga agattgtaaa 192840 gaagtaaaag atcttaaagt tagaaatcat tttagataag gagattgata aatatgagaa 192900 aagaaattag aaaaaatgaa agtaaacaat tgactttaca agaaaaatgg gaaattgatg 192960 cagaattata cagagagaaa aataaagaca agaaaaaaat aaaaggacca attataggaa 193020 agaaagtttc taaagaagaa atggaaagaa tcttaaaagg agaagaataa aatgtttaat 193080 cacaatatct tactatataa acctattagc attgattata atgattttat tgagttaaac 193140 aaagaaaaat ataaaaatga tagagaatat attaaaatga taaatgtatt taacttaatg 193200 gaactgttaa aaatagactc ttttaaagat aaaactttct ttgaaactga atgtaaatta 193260 aaattaagag gttatgatga atataaaaat ataaaagtgg tttacaatca atcattagac 193320 agtgatccaa tattctctaa tttaaaaaac tttaatgcag aattagatat tataagtaaa 193380 gaaagagata atacttatat gactgaagaa ttattatatg aatacaatat gatgaaaatg 193440 agcacatgta taaatgataa agctaacact attacaatta aaataaaaaa tttcattaat 193500 tcaaataaag aaaattttaa taacgatttt gaattcctta ttaaagaatt tgaaaataat 193560 ttattaaaga atttaacaga cctccataaa tatgaagact tacaacttct aattaataat 193620 gaatatcaca gtttaaaaga tattagtgta tataatgaaa aaatatttag acctgctact 193680 gataaagaat ttaagaatta tttagttaaa gaaggattta gatgaagtat gtattaaata 193740 tatattataa aaatgagata atgaattaat atgattcatt atctctataa taatttaatt 193800 aggagagtgg aaaagatatg attttaaaag agaatagatt ttattataat aaagatatta 193860 atgagctttt tataattggt aaagataaaa gtgatattaa cgataagata aataaattct 193920 attataaaaa attattagaa aaaaatttag attactatca tttaaataat gacctttatt 193980 ataatagaaa tctacgtttt gatttaattg ataatgaaaa tatttatttt agtaatatgt 194040 ataatggaat tagaaagaaa cttccagtgg aagccttaga atttgcatat ataagaatta 194100 gagataatca agtagttgta caattagaaa cttttattac tagaggtgac gatccaaact 194160 ttttagaagt tgaaaagaat gcaacgagtg ctagcataac aatggtaaaa gatttttatg 194220 aaaaagatct tatgagttat aatgtttatg aaaatgattt agataaacta tctaatttgt 194280 tggacacaat gcttaaagaa gaaaataatg gaagtattaa aatttttata aatgacattg 194340 atatatttga acctcatgca tattttaaag aattagaaga tgaaagagaa attaaaaata 194400 ttttggttaa gaaaaatttt atataaagga gataaatata atgaatgtaa atgaatatat 194460 aactaatcat gatttttaca gagttggtat taaaggtcaa gtatttgtat ttaataaaga 194520 tatatcaaaa gatgaattaa attctaaaat atttactaaa ttattttcat gcgaaaatat 194580 aggaattata ctgtccgaat gtggacatta tataatagat ggaaataata tattcttaag 194640 aaataatgat aaaatattat tagtagaaaa tatgactatt gatataagtt tatttaaaga 194700 tgatctaatt gaattaaatt ttatattaaa tattgaatct gatctttatt caaaaattgg 194760 tccttttgaa aaagataatc atgatccttt ttattattat aatactatta ttcaaataga 194820 aaataaagat aactttcaac atgaattaat ttctcatata acaaatcatt ttaataaaat 194880 gagtgatgtt gattaatgc ttttaactac taaaaatgaa attagattta ataaagatta 194940 tagtattaat aaaaaatgta ttaattttaa atgtaatttt aatgaaattt ataaaatact 195000 taataaatta gaagatgaaa aagaaattaa gaaatatata gtaagagaaa attttaaata 195060 aggatagaat aaatatgaat ttagataata ttgtaatatt aaaaaagaaa aatgatggta 195120 aatttgacaa taacaaattt atagaattta atcataataa tattaataat gatgaaatat 195180 taagtctttc tttaattact ctatatacaa gcgtgtatgc attttatata aaaagcgatg 195240 tgaaacctga caattttgtt agttatttag ctaattttta tttagaaata gatgggtatt 195300 taaaaggacc tttaaatata acacatgatg aaaataatag aatgcttata atttataaag 195360 gaagactacc acaagatatt ttcaaagtta gagaatttaa cgtaaatact aaattatatg 195420 cgtatttaat taaagatgat gaatacaata cggtagaaga tgatctaatc gaatcagtaa 195480 tcaatggatc agaatatata atgaatagtg aaagaattaa accgaaaatt attattaatg 195540 gattatataa ggatattaca aatgtattaa attattttga aaaacttact gatgaaaaag 195600 aaattaaaaa atatctaatt aaaaaaaatt ttaagtagaa taaggaggat taaatttgga 195660 taagtcatta tatgtatcgg atatattcga tgagaaagtt ataggaagaa aggatcttaa 195720 taaagatgaa ctttttgatt tgtcatttaa tacaatttta aataattctg ctgacactag 195780 atttaataaa gaaggaatta ggttaatgtt atcgttttca aaaggattaa ttttaaaatt 195840 tgattatgca gacaaatatt tttatgtgaa agattttata tttttaatag aaaaagttga 195900 tggtaactat gaatttaatt ttacattaag tattccagaa tttgcagaca gtgaaattga 195960 aattgaatta ggaatttttg aatcggataa aggtcataga gaattttatt ttaatgattt 196020 ttcttattat aaagaaggaa aaactttatt agaaagagct aaagaatatt taacggttga 196080 tgtttttaat aattatggtg ttatttttag tattttttca ttaaaagata aaaatagaat 196140 tttaacagac gataatttta tcatagataa taatgatata gatgaaattt atagtctaaa 196200 aaatatagat aacgtattta gagaagtaac aaacgaaaaa gaaataaaag aatacttagt 196260 tcagaaagga tttagataaa atgaaaatag gcttagaatc ttatgaatac tattaccatg 196320 atgaagaaaa aatattagtt ccagtatcat tagatatgaa gaaagaaaat gcaaatgagt 196380 taatgacgtt tgaatattat aagaaagttt ttaaaagttt taatcataat atatttcata 196440 aaagaattca cgatgataat atactattta gtactcgatt aaataaagtg attaacaaaa 196500 gtactggtat atcaatacct gcttatgagt tatatataca ttttgaaata gataactcat 196560 taaatattat ttccttagaa ttaagttttt caatggatac aaatcacttt gatttattta 196620 gaacattcta taaagataaa atagaagtta taaatttttc aaagacagat tctttaaaat 196680 ataatcaaaa tgtagataat ttagaagata aaatggcatg tctattagct aaattattct 196740 ttgatatgca caatgatgaa aatgaagata ttgaaatata tgtagacgat ttttaccatg 196800 aatcattaga catagctaag ccatataaat attttagatt gatgggagaa aaagaaataa 196860 aaaatctagc aattaaaaaa acttttaaat aatttaatta actttctttt atattaataa 196920 atacaatgaa agagagttga atataataaa tgtctgaaac taatgaaatt gattaatat 196980 cacaaatcaa tgatatgatg gatgaatata agatgttagt aaaatttaaa gataaaatgg 197040 aaaataaaga aattcaatta gaaaatcgta tacaggattt aactaagaat ttgaaatatc 197100 ctaaacatac attcgtatct aatatggaag ctaacattat tagtgtagaa aaagaaatta 197160 aagacactat tatgcaaatg aaaaatgtta aaaaagatat tattgactta actatgaaag 197220 ctcagaaaat ggctgaagat gatgaatctg aagataatta taaaactctt gctaaaaatg 197280 tacttaatga gcttaataat atgtctaata aagatatttt aaacagtatg atggaacctg 197340 aagaagtaaa tgatgaagat actgatttta gtgaagaatt agatgcaaaa ttatcgcaat 197400 tagatgaaga agagaaatct atcaataaag aagtagatca aaaagaagag ttgagtcaag 197460 aaattaatga attagatcaa caagatttat cttctatatt gaaagtctat aaaggtacat 197520 tacaattctt tgttgtagga gattctcctg aagaatatga attagtagtt gctgatatgg 197580 atatgaatat tattgaagaa gatgagatgg aagatgaata tccagaatta tttactatga 197640 ctagggatct tatctttgaa gatattgaag gtaatgatga aatagttaaa gatgaatttg 197700 gaaatattta tcaaaaagca gaattttaaa ttattttaac ccataatata ttaatacaat 197760 atattatggg tatttattat atgtggaggt tatgtattat gggatttgag ttaacaatat 197820 atggaataaa taaaagtaag caaagagatt tacaatggta tattaatcat catagatata 197880 ctaaagagaa gaaccattta tttgaattag aattatataa accacatgaa ctttttgatg 197940 tattaaaata taaagtaatt gattataaaa atgaagatgg ttttgatatt caagtaatag 198000 atgaaaatac tttaaaagag ttaatggaaa atgaattaag agaaaataat tttgaatatg 198060 gattaactca atactataga cttatgactg aaatatccag aaataaatat tttataaata 198120 atgataaatt tgatttttat ctaatcttag atgcatcatt ttaataatag gagatggaat 198180 agatatgtta aaaagattat atagtttatt aactaagaaa aaatttgaaa gaaaattata 198240 tgaatttaaa tttaattatc aagatcatga gcatttaaat caagttcata gagattcaaa 198300 taatatataa tatgaaagga tgattattaa tgttatcaga atatagatta aattcaaata 198360 aagaaaatat taaacaacta ttaagagatt atggttttaa aaaagattct tatactaaag 198420 ctttaatata tagaaaacgt gtaactgatc cgaatgatat tttattcata gtggctgaag 198480 tggttattga aactaattca gatctagtta aattaaatta ctatgatagt aaacataata 198540 gattaatcc ttctaatgag tcgccagaag ttcaaaaagg tttaagtata ttagaagata 198600 tgaaagaaaa agaattatta attgaaccag aattaactca aaatgtagaa gaaaaagaag 198660 ttcttgatag acttaaagaa caacgtgaag aaatggaaaa tggtcaagta tcacccaatt 198720 ctgaaaatta gaataaatat atattataaa aatgttatcc caatactatt aaattagtat 198780 tgggattatt ataatagaag gagttaaata aatggagaaa attaataaat actacattag 198840 taaatcaaaa gatgaattta tggaattaac tttcaatgaa aatgaaacac tctattttga 198900 ctttaagtgg aaagttttaa gtgagctatt cactacaatg caaataaatt ataataagag 198960 atttcttata tctcatgaag aacatgatga cgatggttta gttgggctta gaataaattt 199020 caatgctttt cccacagtta aatacaaata taagggtaag aaaaataaaa tggaacttct 199080 tatatacgct ataatacgct ttagtctaaa tgaggaagac gataattata ttaagtttaa 199140 agctgttcct ttatataata atagtgaaat agggaaaaga ttatttagta aaagatctgg 199200 tatatttgat gataatggtg aactagattt accgcatgac tttaatgaag aagttatgat 199260 tcgcttttta aaatatttta aaagtcatat acaaaaaggg aaaagacctt tagaactcaa 199320 ggacgattta cacaagatgt ttactgctac aaataaatta atttttgaat tactagatca 199380 gatacaagat cattcagata ttgaatttct tattgcaccc gattgggatt ttagtggtaa 199440 agaaatggaa aaagaaaaag gttttagttt tgaaaaagaa tatgataagt atatcagttt 199500 aaatgatttt gatgttgatg catattttag agaaataact gatgagaaag aaattaaaaa 199560 atttaaagtt aagaaaggat tttcctaata tgaaaaataa tacaaaatat tttatagata 199620 aagaaagaga tgaattaatt gaaattgata agaattatct taaccgatat gaatatattg 199680 catatgtatt aactactatg gatattaata atcttttaag cagtaaagga tatgctaaag 199740 ctttcataga taatatttct aaagaagaag gttgtatgaa ttttcatgat atagattctg 199800 atagcgatat ttattttatg gacaaacata ataaaaatga tactcttaaa agatttaata 199860 ctaattttca tattaatttt aatgctggta gaatggataa aattgaaagt ggagaattta 199920 aattagattt tcattttgat aattcattat ataaagaata tttcaatata atcactaatg 199980 gtttagtaaa tgaaaataat ttagttaatg aaggaataaa tgaaaaaatg agagctctta 200040 taaatattga atcatttgaa aaaaatttat atgagatcaa atatagtaat gaatcattta 200100 tggatttaaa tttttcaata tcgggatatg agaaaagtcc tattattaaa tttacagaaa 200160 aatttaaaga tttattcttt ataatattat atcagaataa tcttagtgta ttaatgtctc 200220 tttatgagat taaatatatg tataaagacg atatagaatt ttatattagt ttctccagta 200280 agggtggcgg tttaattaat ttattacacc taatagaaat tgatgaaaat aatttattta 200340 aagaattaac agatgaaaaa gatattaaaa attttaaagt taagaaagga ttttcataat 200400 ggaatataat aattactata gatataaatt agatggagaa atacttcact ttgatatgga 200460 tagaactgac ttaagaaggg atatattggc tgaaatattt actaaaatgt atatgaaata 200520 tattaataaa gatgaagaaa tgattaaaac gtcagaaaat tttatttatc gatctgatct 200580 ttctttagaa tattctcatt ttaaagataa agtatgtgaa atcagacaaa tttctaaaat 200640 aatgggtaaa aaccatgtaa aagatttatt aatttacgat acagatatta gtttaggatt 200700 taattctatt ttagatggag ctatatttaa aaaagattt ccagaaggat cttttcatga 200760 caaaatagaa agtaacatga atagaagata tttaatttta agtgataata taagtcatac 200820 tagtgaaagt tttgctgatt tatatgacaa agattatatt ttaaattttg aagaagtaga 200880 atttttagtc aaagaattta atagaacgtt tttaaattat cttatggatt taatgagtta 200940 tggaaatcta gaattaaatg ttagaaaatc ggagttagca tattttatga cagggatata 201000 tacaaaaatg aaaaaacatg aagacagatt attccctata ttcgattata aatttttact 201060 taatgaatct ggattatttg aagagattac ggatgaaaaa gttattaaag aatacttagt 201120 gaaaaataat tttaaataaa ggagatcaat ataatgagtg caatgaaaag taataaaaaa 201180 tacttcctat gtaaaataaa tgatgaatta tttgaagttg ataaaaacaa tagaggttca 201240 tttttatatg actatttgcc tttaataata gctgaaaaaa taattaatca gactgaaaaa 201300 gattcatatg aaactagtgc aatggatgtt tattataaaa aagaagataa tataattaaa 201360 ggtaatttaa aatttttatc aagatgttta cttcctgtcc tgtataattt caataataaa 201420 aattcattta aaaccgttat gactctcgca gattttaaat ttaaaaggga tgctaacaaa 201480 tctactttta gtatagataa aaatagtgtt aatgataaaa tactatttca aatgagacct 201540 ttaggaaatg aaattgatga tattttattt aatagtatta taagtgacct tttaaatgaa 201600 gatgacgaaa tagaaatgaa acaaatgtta ttagttggta attttgaaaa attattaaac 201660 gaaattgata atcaaaatat aaaacatcat gatgatttta aaattttaat caaagatata 201720 tttaatattt atattaattt attaaactct ttaagtcatc atcttaatat tgaatttttc 201780 ttttctgaat cttctttttt agacatgtta aatgtttatg attatgatat cattaataat 201840 aaagatagtt ataaaataaa tatttttgaa gatgatttag atggaatatt tgaagaaatt 201900 accgatgaaa aatttgttag agaatattta gtgaaaaata atttcaaata aaattaaaaa 201960 tttatagtaa cggaaatata tttatcaata ggagttgaaa ctggataatg aagattaaaa 202020 gattaaagtt aaagaatttt atcggtattt atgctggtat gggattaaaa gaagttgaaa 202080 ttgattttag taaaagtaaa aataatatga ttatgcttct tggagataac gcttcaggta 202140 agacgacagt tatgtctaat cttaatccat atagagaaac taatgatcaa cgtaaaacta 202200 tagtattaga agatgaaaaa ggtataaaag agattgatta tattaagggt aatgatgttt 202260 atgaaattaa acatcattat ggtaaaaaca gttctcaaaa taaatcattc attaagaaaa 202320 atggtgaaga acttaatgaa aatggtggta ttaaattatt caatgaaata gtagataaag 202380 aattaggtgt atctaaagaa tactttactg taggtcgttt aggcgataac gtatcaaact 202440 tcattgacta tactacaggt gatcgtaaat catatatcaa taaatttgta cctaatattg 20500 atagatactt agaagcttat aaagtagcta atgagaaatt aaaaattatt actaaagatt 202560 taaaatcact tagatttgat ttagacaaat ataaagaatt tgatgaaatc aaaaaagaaa 202620 aagagaattt agaaacttta attgatcaat tacaaaatga acttgatgaa gctaataaag 202680 ataaaacaac tcatgaaact aaaatgaatt ctatcatgga agataagtac aaagagattc 202740 atccaactga atataaaaat caattaatta atgaaattaa tgaacttaat caagaattag 202800 aaaaagaaag aaagttaaaa gaagataatg agaatttaaa taaatatact attgaatccg 202860 ctaatgagaa aaaagataaa atagatacta tattaaataa tactaataat gagttgactt 202920 ctgttgaaaa agataaagag aataatcaag ataaattaga tgatttaatc agtagaaaat 202980 ctaaaataga atctcgtatg aatgctatca aatttaatga agattatgat gcttctgatg 203040 aaattgattc aattcttgaa ggatataaag aagatttaga aggtattaaa gatgatgtag 203100 atatttctag agggtctttt gtaagtgaat tcggtttaca aattaaagat aatattaaag 203160 aggattcatt aagattatat gtaaatgatt taatttctaa ggtagataat tttaaagaat 203220 ttattaatga taatgaattt aaatatggtt ctattcgtgg agattttgaa agtgaaatta 203280 aagataataa tgaaaaaatt tctatgaacc agaatgaatt taatgaaatt aatactaagc 203340 ttaatcaaat taaaggcaaa tcagacttat taaaaatatt agatcaaaaa gatcatgatc 203400 actataatga atgtgtattt gttcctttag tagctgactt taaagacaat gaatttgatt 203460 caatctctga attagaaaat aaaggtaatc aactttataa agataatcaa gaattagaaa 203520 aagataataa attattatct aatcatattg acttattacg taaatttaat gacatactta 203580 ctagtagaaa tagtttaatt gaatatattg gttttgaaat gattgatatt gatagtattg 203640 aagaaatatt tacaaatggt aatacattct ctagtgaact aaatagactt aattcattaa 203700 ttgaaaagac aaatgaaatt cgtactaatg aaactaatag agataaattg actattgaat 203760 tagagagaaa agaaaatgct cttaaagaag attattctaa taagaaaata tagatcaat 203820 ataaagaaga taaagaagat ttagttaaac aaattgaaga aattaaaaat aaaaataatg 203880 aaatttctga gaatcttaat tatcttaatg gtcgtaaaga aaaagcaatt actaacttaa 203940 atattattaa tgaatttatt aatctaacag agagatctga agaaattaaa ttaaaaatga 204000 aagataaaaa tgatatagtt gatgacattg ataaggatct ttcaaaatta agtaatttat 204060 atgaacttaa tcaaaaagca gacaataaaa ttcaatctat taaagataat ttaactatga 204120 agaaaaatga tttagaatct actaaagaaa aatactttgc agttaattct attattacta 204180 agattgatga aattgaatca gtgttatgga aatataatat ggtggtagat tcattaaatc 204240 ctaagaaaga ctctatacca ttaatattca tactaatta tcttaaagat attgcagtaa 204300 gtactaatga attactttca gttgcttata ataattcatt taaaattgac tttgacttaa 204360 cagataaaga tttctttatt aatgtgtata aaggtaatgg aactgagctg aaagatatta 204420 aagaagcttc tcaaggagaa acagctttaa ctaatattag tttatcttta tcattattaa 204480 acaaagtatc tcaagattat aatattctat atttagatga aatggactca acattagatt 204540 ctaataatag aagaagattt gttgatgtaa ttgacagaca aattgaatta atgggtctag 204600 aacaagtatt cttgattagt cataatgatg aattctatag tgctaatatt gacttaattt 204660 tacttaaagg atacgaaagt aaaattgaca ttaataatga agaaatgatg caaggtaaaa 204720 atgtattatt taaagtaaac taaaatttgt tattaaaaat ttgagaggag taactctatt 204780 tgaatattaa tgttaataaa cctttagatg ctaaattcga aaaagaaatg catgataata 204840 ttataaatgc attcattgat agcacgttag gaccaatcct ttatgaaaaa ttagaagagc 204900 tatgtaaaat tcatgataaa aatataaaac tttattatga ctatgatatg ttagattcta 204960 aaaaattaaa acatagtttg attaaatttt atgaagaaaa taatttagat gaagacgaat 205020 tcattataaa gattaaaaaa gaagttgtta aaaatgcgtt taaatagaaa aggatgattt 205080 tatatgaata aaaagaaatt atggataatg acaggtataa cttttttaac atctttcacg 205140 ataaatttta ttattctata ttataaagat aaatatagac aggatgatat tgatacatct 205200 gaagatccat ttatgaaagg tccattattt atatagttta aatattgcca aacattcttt 205260 aaatagagtg tttggcattt atattttaat tttttatgaa atctaagtaa cgattaaatt 205320 atcaaagtag caattgaatt gaggagtgtt caaagataat gggtagattt attaaatcaa 205380 catatttaaa taaaaaagag acacattcag gaaaagaaaa agtggtaatg gtagttaaag 205440 aagaagacgg taataaaaaa cacatggaaa taactgatcc gatgatgcat tactatgtaa 205500 ctaaagatga acattggtta ccgcctaata aaattgtagg ttctattgaa aaagataaag 205560 taagaactgt tacttgtaag cataaagata ttatcaaatc agtagttaaa gaagctggta 205620 atgctcaaga taaagcagaa tatgatagaa ttatgaaatc aggtaattgg caagaatata 205680 gaaaattaaa agattttcat ttattaaata atgctcatgg atctgatatt aatatagaag 205740 attataatat taatgagtat attaaaaaga atttagatag taaagtcggc atagatatat 205800 gtctattcga tattgaggtt gatggttctc aagtaactgg gttaaaggta gctcaggata 205860 aagcttttta attgctggga agtccttaga gcttaatgaa ctacaacgta atgagtaatc 205920 ataagcgtga atgtttaaaa atcattaaga ttggaaaatc agcagctaat aataaaattt 205980 aattgaaaat aaaatttaag gtatgataaa gttggaaata tggaaagata tagaaaatta 206040 tgaaggttat tatcaagtat cagataaagg aaatgtaaaa tctttagaaa gaaaagttat 206100 tgaaaaaaaa tactggcaaa gtcaatattt ataaatctag aaaccttaaa aaatcatata 206160 ataaaaaagg ctatgagcaa gttagtttga ataaagataa taaaaagaaa actatctttg 206220 ttcacagatt agttgcgtct gcttttttag aaaatcctaa taatttacca caggttaatc 206280 ataaagacgg tataaaagat aataataatt tggataattt agaatgggta actaatgcag 206340 aaaatatgga acatgctcat agtacaggtc ttatgaaaca tatcaaaatg ccttctggaa 206400 aagatcatca catgtttggg aaaacagctt ataataaagg taaaaaaatg agtgaaaagc 206460 aaagacaggg tatgatgaaa cctatcttgc aaattgatat gaaaactgga gaagtagtta 206520 atgaattttc aggagctaaa gaagcagcag atattttagg tttttctaga agatcaataa 206580 cagatacatc aaatggaaaa caaaaaagtc ataaaggttt tttgtggaag aaaaaataat 206640 tcaattaaat tttattaaag ttcaacgact atcaaaagca tgtcaaatgt gagtagagta 206700 cagccaagcg gttagttttt aagtgatatt agcttaatgt aatactatta aatggaaaag 206760 gaagcatctt aaattttaag gtaagatata gtctcaacgt ttagggaaac cctaaagaag 206820 ttcataagag aactggtata tattagcgat atatattgaa gattttgtcc ccgaccctga 206880 aaaagctgag gcagaggtaa atattataac tgtagtggac tggagtaaga agaaagtatt 206940 aacatttgct cttaaatatg atactgatac ttatagagaa actatgaaag atcaagataa 207000 attaattaaa gacttaaatg aaatttataa taatgaaaat agtgaaattg gtaaagattt 207060 aggtttagaa tttgaaatat atgagttaga tacagaaatg caagttatta aatctttctt 207120 gtattatatt aatgaaatta gtaagcccga tatatgtacc gcatggaatc tagattatga 207180 ctttcctgca ttatttgaac gtattagagc taacggagaa gatcctgcag attatttctg 207240 ttctaaagaa tttgaagata aaaaagcata ttataaatta gataaaaatg ctactgatat 207300 ggctaataga tcttctacat ttgagactaa ttcatatact aactggattg accaattagc 207360 tttatatgca aatattaata aacctaatgg tgctttggaa tcagttaagt tgaatgatat 207420 tggagagaaa gaagcaggag tactaaaga tgtttatgaa ggttctattt ctgatttaca 207480 ttttagagac tattatacat tcattcttta taatattaaa gatactgtat tagctgcatt 207540 aattgaacat aacactaata tgtttgattt attattctct attgtagaca tgactagaac 207600 aagacctagt aaagcactta agaaaactat ttgtttaaga aatcgtagtt cagtattctt 207660 tgaaaatcaa ggatatgtat taagtaataa tcactcaaaa ttattatcag atccgaatgc 207720 agataaaatt cgtggtggat ttgtagctga tatgatgtta attgaacgta atggtgatgt 207780 attagttaaa ggtaaagata ttagatctaa tagattattt agtaatgttt gtgactttga 207840 cttaagttct ctatatccat ctattattag agcttataat ataacgcctg aaggacatgt 207900 aggtaaaatg aatattcttg ataaaaatag aataacagta cctaaatatg aggaagataa 207960 agataactat gatttcaata ctgaattcgt aagtaagttt aatagtcaag atagtgttgc 208020 ttttgctcaa gaatttcatg gtttaccttc tcttattaaa gcatctgatg acattattaa 208080 agaattagag gaggaaattg gttaatgtct attattattg aagaatcaaa aatagtaaat 208140 aaattagtaa tgacttttga agaaatatct aaattattca ataatattgt tgatggaagt 208200 aagtatatta gtttaaataa aaatattata acaaatcatt ctaagtcaga tgacaatcct 208260 aattcagttg aagtggaaat tatagaagat aatccaattt acgattatct tctacctatt 208320 gaaaattgtg tttttagtgt agaagacttt attgaagtaa gaaagaataa gggagataaa 208380 attgttaaag ttgaattttt caatgaaatc gataatagtg gtattaaaat aactagagaa 208440 tctgatttag aaactattat taacggtgat gaatttgatg aagacttatt agatgaagaa 208500 ttaaattatt cactagatgc tattgattat tttagttctt ttgaaccaag tctaaatttc 208560 aaattagatg atgatagttt attggaaatc aaggaaagaa aaccttctga gttctttaag 208620 tttatattta ctgaagatga tgttattgtt aaagatcctt attatattta taatgaagaa 208680 gactacctta ttgattttag aacttctaaa aagtatttat taggattaaa atataaaaag 208740 actaaaggag aaacagtttg tccattagtt aaaatagatg tatacgcccc agaaacaact 208800 gtatatagtg aattgattat gataaaattt tcaatttacc aagacaaatt tgttgcaaaa 208860 ttgaagaatt tagtttataa tatataatgt gaaaaaatac ttataaatta agagaaaatt 208920 ctaaaaagta ttgaaaagga gtgttttgaa tttggctgat gagaataaaa ctcagagaag 208980 tataaataat ctcaacagag atatggtcag aggattagga gatgaagaaa atcctaagaa 209040 cttatctgat aatataaatg attttgatga taggctaaaa aagataagac gtaaaagtaa 209100 tcatggtaat agtaatggtg atattctatc tttagcatct aaagtaaatg gtaaagatag 209160 aaatgctaga agaactaata atacaagtga tgataaaaaa gatttcatta aagactttat 209220 agaagagaat attgaaaatc aagatttttc atctgaaatt gctagagtat ctagatatga 209280 tgactataga attatagata agtttatacc tgaaatatca acaagtattg atgtattcgc 209340 tacttctatt atcgcacctg acgatacttc taaattatca ttgatgtatc gttatggtga 209400 tacaaataat aaagatgaat cagaaaataa agaagtttta aatgaattag atagaattgt 209460 aaagaaatat aatttagaca atttaacata cacttctatt cgtgatggtt tattattagg 209520 tgatgtattc tacattatta aagatactaa atctgatttt gaagaaatac ttaatgaaaa 209580 tgatgatgta ttaggaagag aaacacgaga agatcaaaaa gtgattaatg aatcatttat 209640 agatcagaat cttaaagaat ctgatttaga cattgtaatt aatgaattta atagtcaatt 209700 tgaaaaacct attaaagatg aaaatcaatt aaatgaacaa agagctaatt ttaaaaatga 209760 aatattaaag agcattaatg agaatgtagc tttctttgaa aattcttctg aattactatc 209820 tgatataggt aaatacaaag gctctaatga cttacaatca tttttaaata aagcagataa 209880 caaaaataaa tctagtaaat taaaatctgg ttcagtttat tttagatctg tagagcctga 209940 agacatgatt aaattagaaa ttgatggaat gtgtattggt tatctttata ttgagcctga 210000 ttctggaact gattaagag gaggagctaa tcctttatta tctgccatga ataatttaat 210060 gggtgacggt tatcagaaac aaggtcagac agggtcattc gcaaacggta tgggagttac 210120 taacttagat cctgttactg gtaatgttgc aggaaataat atgtctagca attctaaaaa 210180 tcctaattca ggaatgaatg ctacatccgg ttcatattat gaaaatggaa atactgctat 210240 ggcgtatcaa ggactagttg atgttatagt taaaggtatt tctcaaaaaa ttaatatgga 210300 cttcattaat aaaaatgatt catttaaaga tattatatat agattaattc gtaagaatta 210360 tattattgaa aatggtatta aaatgacatt cttagaagct gatgaagtat ttcatcacaa 210420 attagacagt caaaaaactt atggagtttc taaacttaat aaatcattat tctttgctaa 210480 attatattta agtacattaa taactacaat gatggttaaa ttaaatcaat caagagatag 210540 acgtgtattt agagttaatg caggtttaga tgatgattat gaaggaactg tagaagaaat 210600 aattcgtaat gtaagacaaa atgaaatgtc tacaggttta tttggtgatg gaacttcagt 210660 tcaaacatta tttaatcaag taggtaactt agaaaacatg tatattcctc aaaataaaga 210720 gggtacttca cctttagaaa tagatacaat ttctggtatt caagttgata ttaatgatga 210780 attcttagaa tggcttaaga aatcagttat atcaggtaca ggagttcctt taaattatat 210840 tgatgctgag actgaaactg attacgctcg ttcattatca atgcagaata ataactttgt 210900 aagacgtgta gttaactatc aaaaatcatt cggtgaattc tacactcaag tattaagaaa 210960 gctttattat ttagaaaatg taaatattaa agataaaaaa tataatgaag aattaaataa 211020 taaattacaa gaaattgaag cttacttccc agcacctgta ttcttaaact taggaaatct 211080 taatgaagaa gttggagctg taacacaaat gatagatttc ttagttcctt tatacacttc 211140 agaagctact ggtgacgaag aagaagatga taatgaaaaa ttaaaacgtc tattccgtaa 211200 agaactagtt caacaagaat tcatgtctaa tttagattac gatagatatg aaaatatcat 211260 taacaatatt aaagatgaaa taaataaaga caaaaagaaa aatgacatga caaacaataa 211320 taatgctgat ggagacgatt tagcttctcc aaatgattct gaaaatgatt cagatgataa 211380 ttttgaggac gatttctaat attgacattt gaataacgga ctaaatacaa ttcgttattc 211440 aaatttatat tatataagtg tagtacataa tatttattta taaggagaat gaattagata 211500 tggcaaatga agaaattgtt ttagatttaa aattaggtaa gtacaatgat tatttacact 211560 cagataatta ttttgaaatt ttagatgatt taaagaaaga tatcattggt aatcctcaaa 211620 aaagaatgga agactatttt gaagacaata tacccaaaag taattatttc actttattag 211680 tattaggtaa accttttaga gatatgaata aagaatttac tgaagagtat ttagttaatc 211740 caaccgatat tgatgattat tatgactatt ttgacaaagt tgttgttaat tttattcatg 211800 aaggtcatga tccaataaaa gttagtcaat caattgcatt tgttattgac gaattgacta 211860 tattttcaaa tgaatatatt ttacctttag atggtccatc tatttcatta tatgatatta 211920 tgagattagc taatgaagat aaagaaatag aaaaattaat taactttgat aaagaagaca 211980 ttgatcataa cttaacatat caacaaatca ttaatgaagt tcaaaaaccg aatatgcata 212040 aattgattga tcgtattaaa tctgataaag aaaacgatta taaaactttc ttacattcag 212100 gaacaggtat taataagata caattgaatg aggttttaag ttttgtagga tataaaccag 212160 acattcgtgg tgatgttgta actgatatta ttgatacttc atttatgcgt ggtttaaaag 212220 atacaacaca atttgctatt gatgcagaat cttcattaaa cgcattaatg aactctaaga 212280 ataaagtacg tgaatcaggt tacttaaacc gtaaaattac tttattaact tcagacttaa 212340 aactatcaga aactgaagat tgtgaaagta aacatttcgt ttacgttaat atggatagtc 212400 aagataaatt agatagattt aatgatagat tctattatga tgatacagat caagaattaa 212460 aattaattaa ttctaaagaa gacagtcatt taataggaca aattgttcca ttacgttcac 212520 ctattacat tgctgaatct aaaggaaaaa tttgtcaaac ttgttatggt aaacgtttat 212580 ataacattaa tagaaactta tctgtaggta tattagctac attaagatta acagaaccta 212640 tgactcaaaa attactatca acaaaacact tacaggcagt acaattatct gaattctctt 212700 ggccagatat ctttaaagaa cactttgaat tctctggaga taatattgtt ccacgtaatg 212760 aaaagactaa agttattatt gatgaaatga ttattaatga agattatgaa tatggaagat 212820 ataaagctaa tagttttaaa tttaaagtag gtactaaaac tcatactgtt aaatcacctg 212880 taactcttaa aataccagac caaaatattg agactatgga taaattttat gatgaagaag 212940 aaaatgcatt tatattcagt atgaaagact taaaagagaa tttcttattt aatattaaaa 213000 ttaaaaatga aggcgttgct gacccacttc ttaaaatacg ttctatatta gaaagtacta 213060 aatatattag aaatgactat gaagaaaata attatcaagc tatgtttaat gatgtaacag 213120 atttattact taaatcaggt acagacgtta tgagtgttca tttagaaact attattagaa 213180 atatggtatt cttaaatgaa gattataaag aaagaactaa atatagagac cctgaatttg 213240 aacctgatat tgaattgaaa aatgtaggta gtgctatttt aagttcacct tcaccagttc 213300 aatcattaat ctttgaaaag attaaagctc agttaagcac tgatgaaact aataacttct 213360 tcagtaaaga tggagattca atgttcgatc cattatttga ttttgatatt taaaacaata 213420 taattcaacc aaacttctat taacttagga gtttggttat atataataac tctaggagga 213480 atttaatatg aaagcagaag atttattaag agacaattta tatgagcaat acgattataa 213540 taaggatgat aagttagaaa aggctataat gaagaattgt tatatcattt ttgacaatgt 213600 aaatgaagat ggagagagaa atatctatag aatatcagat ttggaagtaa atgaaaatca 213660 aattttatca tttattttag ttaaagatga tatacctgtt tcaactcata gtttttcaat 213720 tgaaaatgtt tatgaattta atgaacttga caagcttata ttagaaagta ttaattctta 213780 aaaaattaat tttttataat aactgataga tataaaattt taaagcaaaa aggagaattt 213840 aatttaacat ggaaattttc aaattaaaag aattagaagg taaacaagaa caaacaatcg 213900 aattaactgg tgatgataaa aaccttaaag aaattagaga agcatttttt aacagtcaat 213960 caggtactta tatggtaaat aaaactatca atgataatat tgaagaattc ttcaaacatg 214020 ctgaagatgg tgtaactgta gatgatgttt ataaacttaa tgtaattgtt gaagatgata 214080 aacaaattac tttagttaaa gctgaaaaag atgatcaatt taagaaaggt tgcttctata 214140 tggtatttga cttaatgggt tctgtacctg tatatactga tttagaaaat cctgaagcta 214200 catttgattt gtctggtatg tttaaagagg atggtttcga tttctttaaa actattgcag 214260 aagtattccc tactactatt gagcttaaac aataaagaaa gaagctgata ctatggtagt 214320 attaaacgaa acaagaaaaa taaaagtatc tgtatatcct actcgtatat tagttgaaaa 214380 ttacgagtta ggattttgtt ctgcagtaga aaattattta tcagtatggg ataaaatata 214440 tcataaacat acttataaag cttttaagta tgatgaagaa aataaaacta tatcttttcc 214500 agcaggtatt aatactaaat tattattaca gtcattaaaa aatcatggag aaattgatta 214560 tcaagatttc agagcagttg aaaatttatt ctttaaacct aaaccaaatt acgatgttga 214620 aatgaatttt aaacctagag atcttctaca aagaaaagct atagaattct taaattcatt 214680 tagtatatat gatccatcaa cacaaaaatt cctttcatta caaactggtg aaggtaaaac 214740 tttctgtgct ttaaagtcag ttattgacag agaattagta cctatgattt ttgttaataa 214800 caataaactt aaagagcaat gggaagaaaa aataaaagag tacactaatg ttgatgatga 214860 aaagatatat gtgattcaag ggagatcaag tattaataaa ctatttaaaa tgaaatctaa 214920 agaaagaaat aaaatagatt tctatatagt aatgtataaa acgttaaatt cttttattca 214980 agaagacgaa gaaagatac aagaattact attaaaaact aaagtaggta ttaagatatt 215040 tgatgaagca catttagatt ttcgaagttt aactaatatt gatatacaaa cagatttacc 215100 atcaatatac ctatcagcta cacctagaag atctgataaa tcagagaata tggtatttag 215160 caatatattc ttaaaaacac ctatatttag ttctgataat tacgacagac agatagctaa 215220 taatagaaaa ataccatcta aatatcatga tgtatttatt atcagatgga atagtaatcc 215280 taaagaagtt gaattagctg atttcatgaa agcttctaaa cgtaatggtc ttaatgtaaa 215340 tcattatagt aaatacttaa ttgaagaaga taaaagaaga aaagaatact ttgatattgt 215400 atttaatatt attaataatg tcattatgaa agaagaagtt aaaaagactg tagttatgtt 215460 taaattaaag aatatgatag atgattttta ttcatattta gaagataaac ttggacctga 215520 aggattagaa tttttaaatt gtattagata ctatgatggt attgataaag aagaaaaaga 215580 taaagtatta gaatctaact taattattac cactgattta tctttaggaa ctggaataga 215640 tatacctgat ttaaaagctg taattaatac agttccttta tcaagtgaaa gtaaagtaac 215700 tcaaattatg ggtagattaa gatatattga aaatgaaaaa ttgatgttct ttgatttaat 215760 tgatcatggg tttaagaaat tggtttctca aggaagtaat agattaagaa atgtatataa 215820 gaaaaaagct ttaaatataa ctgattttaa aattaaataa tgaaaggttg ttgaggtatt 215880 gtgtccatta tatctcgtgg agaggctatt gataattatc aatacctcaa tgaattattt 215940 ataagtttta gaaaagaaat taatgaattt ttatctagtg agatatttaa aattaatcat 216000 actgatttta aaaactctat tataggtagt gttaattcag aatttaaagt taaggaggaa 216060 aaagatcaa tatgcttatt gttagaagat aaatttattg aattcgacct ttatgaagga 216120 tttattatcc tttacaactt taaagagaat attagtttaa tgaaagaaaa aattgatatt 216180 caaaaatcta taatagaaaa taaattagat actagatata attctaataa taaacttaaa 216240 aataagaata aaaagtttaa caatgaaata actgaaaaga ataatgaact taatgaaaga 216300 attaaattag gtgttttaac taatgcatta ctaaatatgt taagaatgcc caattcattt 216360 aaattaaaag aagaaataga tgaacttaat aaaagtattg agaaaaataa tctaattata 216420 gagaataatg atagtaatat aaaattatta gaagaagata agaaagatat tagtaaatat 216480 gattttaggt ttgccaatga taaatatcta ttcaataaga ttagtgagtt tgtacagtac 216540 tttaaaaacg aatatggttt tgaattttat attaaaaatg atactatata aggagtaaat 216600 atatgaatag agaattaagc aaattaagtt tagaagagtt gagtgattta aaagaagaaa 216660 tcaatagatt tttcaataat gatttattta aatttccaag aaaaggactt gtagaacatt 216720 taactttacc tgtagaacat tataatcttt taataagaaa tataatagaa gatagtgaat 216780 tgaaatttac ttttgttggt gctgatatga ttatttttga tttaaatgat ttgaaggtga 216840 agatgtctaa taaatataaa cataaccttc aattagccaa aaaatctcta tactataatt 216900 atgacggttt ttcaggtaaa gaaagacttt cagatgtaat aaaaaacgaa aaagagttaa 216960 tagaagaaag gtttttattt gaaaataata taaaagctat taataatgaa atatcaaata 217020 tagagaataa atttggtatt aaatttgttt ttagtgaaaa ttttgaagga tacgaaatag 217080 aaataaatga aaaatctgat gaagcagaaa tttatatttc aaaaaataaa gaagaaactg 217140 aaaaagaaaa tataattgaa gatgataaga tactaaaga aagtaatgaa catgaaatta 217200 cacatagtaa aaaagattct ttaattaaaa gaataattaa gagagtggtg aaattttaaa 217260 tgactgaaga aaaattacct gcattaaata ttattgcttc tgcagtaact actacaccta 217320 agactaatac agagtttatt aatatgacat ttatggtgga taatcctaaa tttaaagata 217380 tgtatttaga attttctgat attgatttat cagaagtatt taaaaacgaa atgcttaaag 217440 aagcttatga aaacggtcaa ttagcagagt atactaaaat tgatcagact ttagataatt 217500 acaatattag aatgattaaa gatgatacag ttatacaaat acaacgtatt agagattact 217560 ttgaagaatt atctgaatat gctgataaat taatattctg ggttgatgag attactttat 217620 ggtctcagtt aatagaatta gtttatggag gttcatcaga taacacatat caattacctt 217680 catatattga cttccaacct attgacataa aatcagtagt tagaatgtca gctataagag 217740 ataatgatta ttcatatgca gaagaattaa tgggaacaag tgaatcacta acagattcat 217800 ctttatcaat ttcatcattc ttattaacat tcattaaaaa tgctggaata ttaaaataaa 217860 tttttaaata tatattataa agatgtatta gtaatggaat attattaata taaataattt 217920 aaatggagag tgtcagatat tatgttaaca aattttaaag atcatttaca cagaggcgga 217980 aacctttcag tttcaattta tactttattt actagaaaga ataaaaatac tggtaatgct 218040 attaatggtg agtatattaa cacgtatcaa tcaagtcaat ataacggtgt tcctttctta 218100 agtgaaattg aaaataatgg taatcattat atttctttct cttataacaa atttcaacaa 218160 ggtcaagcac ctattcgtga agatgtatta attagttatc cacatttaca agaatttaat 218220 aatttcttaa aagcgactta tacaagtatt agtgagaatt ttaataatat tttctctaat 218280 aatcaagtta atccagatta ccaacaacat atttggcaat caccaaaatt agtgtctggt 218340 aaagaaattg ctattgctcc tgcagtaatt caaaataata gaactaataa ttttgaaatt 218400 ggttttaata ttatggtaaa tgatactaat aaatatgatt ttgtatcagc taatacattt 218460 atcagtttag ttaatttatt agttagaatt actaatgatc cattaacatt cagaaatcaa 218520 tgtgtacaag ctgaaatgca agctaaagaa attgaaaata atcagttatt aaaagggtta 218580 ttaagagctc aaggtttacc tacagatatg agtaatcatc atatggatga aaaatcagct 218640 caaggtaatg ctccacgtaa taataacttt aataataaca gtggtggagg tttcaataac 218700 aataatcaat tcggtaattt cggtggtaat aacggaaatt ttaaccaagc tccacaacaa 218760 aataaattta atcaacaaca atctaataac caatctcaag gaaattcttt tggaaatttt 218820 aatcaacctc aacaacaaca gaatcaacaa ccggtacaac aaaatgacaa tcctttcaat 218880 gtgagtccgc aacaatcagc accgcaacaa agtaatagta gtaatccatt tgatgttggt 218940 caaacggatc aaattagtga tgatgattta ccatttgaaa ctaaagaaac tccacaacaa 219000 gatgatagac aaattgataa atctaacatg tttaaagatg ctgaagttaa caaagaatca 219060 ggttctttag aagacttatc aaatacagta aataatgaaa gtgaaggtaa agctagttct 219120 ttactagacg acttcattaa aaaaggtaaa gaatcagaac aagaagatga cgatttagga 219180 atttaagaat taaataatat atgatctaat atggataaac atctgtatta gatcatatat 219240 accttttatt ttttataaaa aataaataaa gtgagtgaat attatatggc aaataaaaag 219300 gatctaagtg agttagaaag aattataagt agtatggaca ctattgatgt tagagaagtt 219360 tttaaagacg taagaagttc agataatgtt aatgaagaag atgatttaaa ctcatctaaa 219420 tataaaggtg acattaaagg tttagtaact aaagaagaat atgaaagtct tccatattta 219480 ggtaaacgtg ttattcagtt tatggaaaat attgcagctg ataaagaaaa tttagatttt 219540 gaatcttatt ttgaaagata tgcaaaagca tacggtaaag atgaaattga ttcatttaaa 219600 aacactatgt atagacttaa aagtagtaag gtttttacaa tacagtcatt aatgacaatt 219660 actgaagcta ttgattataa agttcatata ataactgaag aattcaaagg tatggatgaa 219720 ttaagattat atgaacctaa acgtaaagtt aaatcttcta gattatggg taaattaaat 219780 tttgatttaa tgccagatgt tatatatgaa gactttatat tagagtttgt agagttttta 219840 gaagaattag gaaaagaagg atatactttt gagatgttat ttggagaact tgaaattaat 219900 tctgatgaga aaaatcctat aagtaaaatt aaatcatcta tggataaaat gattaagcaa 219960 ggtaaactaa cttggaagac tatggaaact ataacagagt ctttaggtat gaatattaaa 220020 gttgatttta taaaagacgt tattgatact gatgaagtta ataaaattga tgcatctaat 220080 caaatacaac tagaagatga taatataatt cataagaaat aaaatatatc ccctaacctt 220140 aaattaataa ggttagggga atttatatca ttttttttta ttctgttgta gtttcttctg 220200 gagtttcttc tacttgtgaa gtagaaatag taacactaac atctttactt acactatcag 220260 aagtgacttt aactttagca gttcctacag ctttagcagt tacaagacca ctgttgttaa 220320 ctgaaacaaa ttcagatcct tctgtaatag aatagtttac agggtttcct tcaggatctg 220380 tagttactgt taattgttga gtttcattat ctttcatatc aacactatca ggagtaactg 220440 ttagactttt agtctttact ctagttacat taacattaac cgtcttacta atagaatcag 220500 aacttacttt aactttagca gttcctacag ctttagcagt tacaagtcca ctactattaa 220560 ctgaagcata ctcagatcct tcagtaatag agtaacttac agagtttgta gatggttgaa 220620 ttttaacgtc taactgttga gttgattctg catctatgtt aacttcttct ggagtaacag 220680 ttagactctt agtctttaaa cggcttacat taacctctac atttttagaa acatcatctg 220740 atttaactgt aacgtttgca gttccttcag aaataccagt aatatttccg ttattatcaa 220800 ctgaagtaaa ttcagaaccg tcttttaatt caaagcttac ttttcttcct tctggttcag 220860 tagtaacctc taatttctga gtttgttctg cttcaatatt aactgtctct ggagtaacag 220920 ttatactttt agtttgatta atgctttcaa attttccatc tttaggatca taaacagaat 220980 attcaatttt cttatcaatt tcgttttgta tagtttcctc atctaaaatg cggatattga 221040 aattaacaat attgtcttga atacttctct caattacttt aactaaaatt tcaccagtct 221100 tactaaagaa taataaacga tttttatctg cttgatatct agcataactt tcatcactaa 221160 catttacaga taataattgt aatagatttt ctttagctac aggagtgact tctttagtat 221220 cgaaatcttt ataacctaag attttatcta aaggtaaagc agattcttta agaacgttaa 221280 tatcttgttg caattgaaca aagacgacctg taaatttacc gtattcttta actttaataa 221340 agactgaatc tttaacacgt tcaaagatgt ttttatgtcc ttcagaaata gcaatgtcgt 221400 aattttctga agcgtcttta gggaagtata atttaagttc atattcttca ttaacttcta 221460 aatcagaagt aggtaaactt aaaatttcag atttaacatc tttagcagta taagttttaa 221520 ctacagactt atctgaaagt ttgattaagt caaattttaa taatcctaat acatcacgag 221580 catctacagg attaatatag aaaggtacat taataaactt accagtttct ccttcagatt 221640 tgaagtaaac tgttcttcta tcatatttaa ttttaccagt ttcaggaaga ggttgaacat 221700 cagtaacagt ccaaccagct tgttttaagc tagctagatc attactagaa agaataacgt 221760 tttcacgagg tccacgttca cctaatccta aaaatggaat taatttttca tctaataatt 221820 ttactttaaa gtagttagta gtagccattc ttagaattca ctttcctttc tttatttttc 221880 taatagtaaa tcaattaaat cttgtttacg agcattttta ttatactcaa tttctttaga 221940 atctaattct tctttaagct cagctacagt gaattcattt aaatcttctt ctgtaacttc 222000 gacttcttca gaaccttgtt cttctacttt ttcttcgtta gtaggagctt cttcagaact 222060 ttgttcttct ttagtttctt cttttacttc gtctgatact tcgctatctg ttccttcatc 222120 cacttgcttc tcttcgctgc tgctttcatc attgctctgt tcctcttgtg attgcgtatc 222180 atttgattca gaaactgctt catttttatc ttcactctta ttttcttttt tatttgattt 222240 atcgcttgga tatacatagt cttcatcaac aattgttact tgtaaaccta aacgtctaaa 222300 taaacgaatt tgtgaacctg aagcacggaa aggtttaaca aaaggacctt tacctttacc 222360 aggcacaaat gctttttcat taataataat gaaattatta tcttcattga aatttaacat 222420 aaattagtaa tctcctttac catattttat tttataaata aaagttaagg aaggatctta 222480 taaaaatcct tcttaactaa atgttcccca tgcgttacca atacgttgtc ctttaccatt 222540 tgatttacca attggcacgt atacatattg tcctttaaat ttacctgaaa cccagataag 222600 accatcaaag tcttggattt cttcgtattt aatagagtcg ccttttttca tgaatggacc 222660 tgtaggccat ccagtccatg gaccattttt acgagtaata attcctgaag caacattaca 222720 tttgaaagta gctttttcag ttttccatag aatacctgct gaattacgtt tccatttagc 222780 agatgtaaca gctttcttag gagctgcttt cttaactact tttttcttag gagctgcttt 222840 cttagtagtt gcttttttag tagctgtact actaaaggct ggacgaatta ctccccaaaa 222900 tcctgtataa tcatggaata ctttagctgc aggtgaacca ttgctacctg cgttaaacca 222960 gttctggtca attgaataga aattgtttaa gttagctgaa gtgataatac ctgtatgacc 223020 ataaacatca tatggaggat tagcccaaat agctatatct cctggttgag gtaagaatga 223080 tggagtattt ttaataagtt tccatcctga aggcattgta ttacttttaa gatctttagc 223140 gttaccccaa ggccagaatt ttccatcagt taaataatta caataaccga tagtcaaatc 223200 catacattga gctccataag ctccatccat gtcaagtcta cgaccaatac gattattaac 223260 ccaattcaaa gcttgagttt tagttttcat attttattca aaccctttcg ataaattttc 223320 tttatttctt tatatttagt tgttctttta taaaaataat atgtttcata atagtataaa 223380 aataaatacc ctaacgaatc tttaatatga tcgttagggt atataaaatt ataatttaaa 223440 ttatagaatc atttattagc taaatgttcc ccatgctgga ccaatacgtt taccgttacc 223500 atttgattta cctactggta cgtatacata ttgtccctta aatttacctg aaacccaaat 223560 atatccgtta aaatcttgga tttcatcata tttaatagta tcacctttag acatacgagg 223620 accttgaggc catccagtcc atggaccatt tttacgagta ataattccta cagatacacc 223680 acatttgaaa gtagcttttt cagttttcca tagaatacct gctgaattac gtttccaagt 223740 agttgaagtt tcagtacttg ttttcttagg tttagcaggt gctttagttg tagtagtaga 223800 tttagttgct gttgaagttt tagctgtaga agtagcacca tttttcatat aagttagaac 223860 ctttttatct acattagaaa cactacgaga cataccgcat gcagctaata aattgcctgg 223920 atcttgtttg tctgcttgga tatcttgatg tcctggcata tttgtacttg cattaatttt 223980 atattcttta cataagaaag caagaacacg acaatagtta tcaaatgatt ttaatgaacg 224040 acttctatta gagaagtaac atccttcaac accaatagcg ccatcattag catcaatacc 224100 ataccaagaa ttatcagtag gtgtattgta cataacatgc catgcttttt catctaaagg 224160 aacacagata atacattctt tatcatcaac aaagatatga gctgatgctg tatagttcca 224220 atcaatatta tatgaattac gatagtaatc aacattattt tgggcagtag tgttagggtt 224280 tcctgtgtca tgagcaacaa taaatttagg tccgttaagc ttatctccag ctctacgagt 224340 acctattggt aaaaaatcag tataaacagg aacaccgttc catgtaccga tatgtttttt 224400 agccataatt aaattttcct ccttgaattt attactaatt aaagtaattt ctatatttaa 224460 ctgttctata tttttaatac ttgatttctg tagatacgat taatttattt tgatatcttc 224520 cacctctagt gtaaacttta ctatcagtgt cacctatatt aatactattt tcagatccat 224580 aagctataca ttcatctaag aataaattac ctcctgatga agcttggaag tcttttcctt 224640 gataactttc aaatgcgata catcctaaat tccacgattg tgtaccttca tttacatcag 224700 ctacattacc tccatcattt cttccatata taccatttat tctaatgatt tttaaacctt 224760 catgagtagt tgatccgtta tttgatttaa caccattcaa tcctttatcg gttccattat 224820 ccattcctat acaattaatc tctattatat taggtttaga accatcagca ccaatatggt 224880 aatttaaacc gtcaaaacta ttataattac ctttacagct atcaagaata atatctttac 224940 cgccaacaat agcaagacca ttgtaacttg aagcagaatg ataaaaatta catttcttaa 225000 agaatgtact gttatttgaa gttaaattta attcaatgca gtttctcccg ccatatatat 225060 ttaaattttc aaaatatata tttgaagcta aacttgttaa ctgtatattc gaagaagata 225120 ttaaaggtat tacattacta tttgaaggtt tattatcatt aatattggaa taaactttag 225180 taccgtcagt aaaccatgaa ttaggtgtac tttcaacttc atcaatacta cttactttct 225240 ttatatcaat actattatct agcgttacaa ctttatcggt agcagatcta ctaaattcat 225300 aagttctatt tttaccagaa gttagtgtcc atgaaggttc atcagccata ataatattca 225360 cattattacc tgtgcctatt atattaatgc tcttattaaa tgcttttgta attaatgtgc 225420 cgccaattct aaaatagtta ccatcagcaa ccataattgt atcattatca ttaactttag 225480 gtattactac tttaaaagat ttaaatgggt tttctttaga taaaccatca ttagaatcat 225540 taccattaac agcatctaag tagtaagtag ttccgcctga taatctatta gtagttatat 225600 catatttcac tccaaaagta ccttttccat cagtaacaat tctatttttt aatatttcat 225660 taccataatt gaaatcatta ggttttctaa ctgttattgg aagggtaggt gcataattac 225720 catcaagacc gggtaaacct tgtagacctt gagttccaat cttacctgta tcacctttta 225780 atccatttaa ctgttcttca gtaaaatcag aatactcgaa aggatctccc ttttcacctt 225840 ttaatagatc taattgttct tgagtaaaat cggaatattc aaaagggcca cctttttcac 225900 cttttaactc ggataattgt tcttgagtaa aatcagaata ctcgaaagga tctcctttta 225960 atccatttaa ctgttcttca gtaaaatcag agtatttgaa ggggtcgcct ttaggacctt 226020 gtatacctgg atcaccttta tacatctcag cattttctac catgtaattc ttaagatttt 226080 ctttgtaatc taataattta ttttcaaaat catctatttt actgttaaat gaatcttgtg 226140 ctaattttaa ttcttcagat ttatctttta taagatttaa tttttcttca actttaacta 226200 catcattttc catattctta acatagtttg tagtctcact aagtttttcc atttcatcat 226260 taagactcat tgtattgtta taattactat tgaattgttc tcttacagtt tcaaaatcag 226320 ttaaagtatc tttcatgcta cttaatttat tattcatatc ttctattgtt gaaattacat 226380 cttctttttc agattgtaaa tctaattttt tatcttcaat actatattta aaactatcta 226440 gctcactcaa atatgaatta agattatcat catcaattaa attttctttg attaagttaa 226500 gtttttctcc tgctttttca ttaatattat ttatatcagt agatattatt tttatttgtt 226560 taaaagcctc attcacttga agatatttct gttttataaa atcttcaata gagaaataat 226620 cagctacgtc atattctcca tctgaattta aatcaacata ttcattttta tttaccttta 226680 catattgaat attcattaaa tcataataat ctaatgtatt tctatcaaca taataaggtt 226740 tatttatagg tcccatacct ttacctggaa tataagtttt ttgaggaact ataattagta 226800 tactatcttc catactatat ttccactcct ttaaatttga tctgtaaaat ccccctaata 226860 tatttttaaa tcgatgatta ttctattctt ataattattg gctcatcgtt taaagttata 226920 tattagggga actaatttta gtcgaaaaaa ctaacgaaaa ttaattttta ttatataata 226980 atgttataaa ttttaaccat taataatttt aaaaatattt tcgtttaata aatctctttc 227040 taatctactt tcttcagaaa gtttttccat taattcttct tctgtatatt tatcaaaaga 227100 tacagaatta tatccattaa tagaaataga agattcatta acttgaattg atttatttac 227160 atttagatca ttaatgcttt cttctaagaa ttttttaaga cgtgtttcat ctctattag 227220 tacattttca taggcttcaa acactatatc ttcatagtat tcttctaatg attcttcaaa 227280 accttcataa agtgaatcat ctttattttt taattggaaa ttaatatctt cttctagcaa 227340 ttctaaatta acttcttcag ataatctttc tttaacatct tcgttaactt catctaaagg 227400 attaagatag ttttctaata aacctgattc tgattcatta ttaacacgtt gaattgtatt 227460 tatattgaat tctttttcta agttttctaa agttatttca ttatctgtat aaaattcttt 227520 aagaacttta tttactttag gttcaactac aataactttc ttaaatccta aaccgaaatc 227580 aactttatca actaataatg aagaaggatt atatacttta ggaacttcat ccatataaga 227640 ttctttacta ataacgatat caacacgttt acctaaagat tcagataaag catttgtata 227700 tctaattaag tctttaattg tgtaagtttc attaacttct tcttcattaa taactttagt 227760 tttaaattca atatcagtag atccacaatt ttcacatact aattcatctt cattaacgtt 227820 aggatcaact gtttcttgaa ctccacattc gttacaaatt acttctccaa cttctttaga 227880 agtttttaaa gcttcttcaa gttctccatt acaattttca catactaatt catttgattc 227940 attcattgtt agattacttc cacaattttc acaaacagct tttccatttt caattttacc 228000 agtttcactt aaaatacgtc taacagtttc aattgattca ttagtaacga aaatttgttt 228060 ttcattttcg ttttctaatt taaatgtatt taatagagtt tcatgaattt tttctgcatg 228120 atttttaaat gattaacta cagcgaaatc agaatcctct ctcatatata cgtatgggaa 228180 agcttgatta tttttatcat caacataatt ttcattagca attatatttt gtttttcagt 228240 attaacttct ttagattctg gagtacctat agcatatcct acttcagcag gtgtgtctaa 228300 tattccattt tttaaatcta caaaagtaaa ttcaggaact ggatctttat cgtataaata 228360 agtttcagta actgctcctc caacacttgg agaaccattt gcagcagaca aacctccatc 228420 actaacagaa cttgcattgg tatttgcatt agaagtactt actgaataag tcgcatgtgg 228480 accaaaagta gtaggaacca tcatttgaga atctaagaat ttagctctta attcagaata 228540 tcttggttgt ttcttatctt catcatcgtc ttctttttca tcttcgaata aataatcttc 228600 ttcaacagaa atttcaggat ctgaattagc tacatcagta atgataactt catctttatc 228660 agccacgatt ggttgatcgt aatcagggtg atccgaatca attacttgaa catcatcttc 228720 atcttcagca tcttcaattt catcaagatc atcagattcc tcatcatcaa tttcttcttc 228780 atcttcatta attatttcgt taaacatttc ttctaattct tcatcatctt caggaatatc 228840 acgttttaat tcttcatttt catcatcatt taaatcatct tcaaataata acatatcatt 228900 tttattttct tcagacattt ttaaatatcc tccttaaatt attttctaaa agttccttca 228960 atactatctt taataataaa taatatacac ggaagtaata cataatcttc catattcata 229020 tcatatttat catcatagta attaaacact tacttaata ttttttcttc tatcttttca 229080 tcattcatat acattgagat taatttatat ctatcatcaa agtaagttaa acttttagtg 229140 ccttgatagt cttcattaac ttcattaatc ttagttaaat tactcaattc tataaaatcg 229200 tttaatccat ctaatacttc agtgtcttct atacttttat gaacgaagct tatttcttta 229260 tacttctctc taaacatttt taagaaatta tccttagtgt cattaagagt aataacatta 229320 ggtaaagtct ttttatcctt taatttttca tatagagaga atttatagtt cttttgattt 229380 attctttcat tcttaggatt tttatcttta taaggtagta tattagaaag ataagtacta 229440 gatttacta atagattatt gtcataaata aatctggata aattcaaatc aatatattta 229500 gttgatgcaa ctgcactaaa ttcatcttca tagtaaataa aagtatttaa tgaagaatta 229560 tagaaatgat caataaatat ttgtgaaaat tcatcagcat atttaatact atgattgact 229620 tgatagaaat cttcttctag tatcaatgat ttattatctg ttccaatatt ggaaaatact 229680 gttctatata cgtttgatac ctgattttca atatcttctg tattaacatt aaaattctga 229740 tattgtattt tatagtaagc tgagttctct agtgaactca tttctacatt agttacacga 229800 tatattctac tagttgcatt ttctttagac tgatattgaa atacaataaa atcatctggt 229860 aaaggttcaa tagtgcctgg tagtataact gcttcagatt ctaaatcttt ttcagttccc 229920 cattcttcat cccattcaat tgtaggattc atttcagcta cattatacaa agggaagtct 229980 tttaatttat tatatttcaa aggagaatta tctccaataa tttcttcaac attatctagt 230040 gaacgatcag aagtagattt ctcatgatct ttactatagt atgtaacaaa actaggagca 230100 cctgcttgaa acttactata tttttctgta ccggataaat atgaggatac gtaactattt 230160 acaatatctt ttggttgtaa ttcatcattt gatataaatg tacccatata ttctcattat 230220 cctcactttc tttattaaat ttcgtatatg gtattgttat ctttgaattt tgttttaata 230280 taataatccc aataccttaa tattatatta ataggtattg ggataaaata ttttataaaa 230340 aattaaagac caaattcttt atctaaagat tcttctaaag aactaatatc ttcattagtt 230400 tgttcttctt ctttaacagc ttcaaataag ctaaataaag cttcttcaac aggacttaca 230460 actgaatcaa ttttattttc catagcttca tttaatttag taggtaattt tttgaataga 230520 gcgatgtatt tcttttcatt atttctagcc caagcttctg cttttttagg actttggaaa 230580 gcacatactc gaataaaacg atttaaaata gatgttttac ctttagcatc aattactctg 230640 taagtaaata taactgttcc atcttcatga gcatctaaag caaattcatt ttcatcaaat 230700 tttttacctt tagcgataac tttagctttc tttttagtag cacgtgctat gaatttttcc 230760 tctgtatctt tatcagaagg gtttaccatt tttcttaatg tatccttcac attagcttca 230820 tttaataatg tttcttgtaa aaaatcttcc ataattataa ttcctacttt cgtaatttat 230880 ttttctatat aatttagttt aatttaaatt cctcatctaa tattttttct aaattttcaa 230940 taactttatc atcttcatca atttcaggtt tcttatcagg ggctttcttg aagatagata 231000 caaatttatt tccattactt tgaacccatt tttgtgcttc tttgaaacga tctgcaacta 231060 ttccaatagg tattcttcga attttatctt tacctttata tttaacaggt acttctaaag 231120 cagcgttttt accaccagta cgtttggcca ctactacaat attgcttgaa tcaattctaa 231180 taccattact tttagctttt attttaaaat tcatacaagc tttagcaaaa tccgcttcaa 231240 gcgtatcagg ttcaacaatt ccttcttgaa ctgcaacatc cgaagtatta ccgcaatctt 231300 cacatactaa ttgacctgat tcatttggag acattttaga accacattct tcacaaatag 231360 gctcttcttt atcagtatca atatcacgat ttaattcttc attaactaaa ccaaattctt 231420 tatctaaaga ttcttctaaa gatttaaaat ccattatatt ttcctcattt ctatttatat 231480 ttattaatat taatgtgtta tcttaaataa attgccctaa tgacaatttt tatcattagg 231540 acaattaaaa ttatagcata tcttttactt tacgttttaa ttctattaaa gctttattag 231600 tgaaaagcat taaataaata tcagtagtca tacgagatac gatacttaat ggagagaata 231660 tagcttcaat ttcctcgtca ggtctatatt ctgcataagg agattcatta ggaggagtaa 231720 catcagcaat aactgtttta catgctccat agaaactgat cttatcacca atactcatat 231780 catcttcata ctctgtgaag atttcaataa gtactccatc tactttctca cctttaattt 231840 tctcactatt aattttctct acagctggaa tatctacatc taatccaggt aatgtagatt 231900 tattatcttt aactgcattt ttgtattctc tatatttact tttagattta ttaatataac 231960 tattaactaa tttagctaat gtaggagaca tattttcaat atcatcatta taatagatat 232020 ttactttttt aatttctcca gtatatttag atctaacagc tctattagaa atatcttgta 232080 tttcttgttc aaattcagaa ccgattttat ctaataaaga accaatacct tcatcatcaa 232140 atgaattctc aaatatcatt aatggatctc ctgtacgtac attttgacct tctttaacaa 232200 tatattgaat atttgtatta gaagctaaat taactgtttt cttcatagta actttagttg 232260 acatgcttc agacatactg ttagaaataa tagaactatc ttcgtacgtg ccatagcttg 232320 aagcaactgc aactttagat aatttaccag cagcaaattg aatatcatta ttactgccag 232380 atcctgcaaa gtaactatca tttttagcta atacttgtcc tttattaaat ttcttaccta 232440 cttcaaattg tggagtaagt ttattatttt gatagaaacc accattggag ttcttagcaa 232500 gtttttcaga tatatcaatt acatctttat ccccattaat gtattcaaca agcattaatc 232560 ctgttttctc attgatagaa gttactttac catcttcttt agctttaaaa gcaaaagtat 232620 ctgaaatttg ataggctaaa gctttatcta caccagatcc aactaaagga cggtcatttg 232680 ttttagttgc tatcaggtgt tttgcctgag taccggtccg atatcttcaa cagagatcgt 232740 aaatctctgc cagttctctt atgaacttct ttaagatttc cttaaagtct agactatatc 232800 ttcaccctat atttttatag gggatcacta tttcgattta agggattttc acccactcca 232860 ttaacttgag ccctactcct gttggtatat ttcaataccc taagggatag tcgttgagct 232920 ttttcctaga caattttcga ttttttcttt tatttttcct tctttttgat ctttataatt 232980 tattcttatc agatctaatt tttcatgatt tttgaaataa tcatctttta ttttatcatt 233040 ctgttttaag gtttcgaatt tttctttacc atttttatat ctaaaaggta taaagtgctg 233100 ctcaccgtca aattctatac aaagattata ttcttctaaa aagaaatcaa ctcttaaatg 233160 atttcctttt atactgaaaa gatcatcaaa tttcttttct ttttcataag gtattttcat 233220 attatccaaa tattcagata tttctttagt accttttgaa tactaatat cactacaatg 233280 aggacagcga tgtcctgatg aataaaaact ttcccaattc atcttaaatt ctcttccgca 233340 ttcttcatgt aagatatcca ttttagttct actattagaa tatgaatttg agactaattc 233400 ataatcaaat ttttctatat aatcttttac ttctttaagg tttttccttt tattaggtgc 233460 acaatgagga caaccataac cctgctgaag attactgtat gttgatttga actcattccc 233520 acataaagaa tgaaatatta ataatttctt tttactgttt tcatattcac tctttaaaat 233580 ataaacatcc ttaccatgta agtcatttaa tttttcttgt acaacttcat tatcaactac 233640 tcttcctgca cacttaggac atttataacc tttaataaaa tttgatggtg ctacatcata 233700 tacataatta cattttttat gttttagttt taatttattt ttgtataatt cgaaatcctt 233760 tatgaaaata tattcatcat aatgttttaa tctctcttta catttcttat ggtattcttc 233820 ttgtttattc aattatttcc aacctttctt acgaaaagct tgtctaggaa cttagttgct 233880 gatcatccaa tcttaatgat ttttaagcat atcacgctta ctgttaccag ttacgttgta 233940 gctcattaag ctctaaggac ttcccagcaa ttaaatgatt ttattacata tacattactg 234000 tataagggga caaaatttat ccctattctt ggactgtctg catgtctact agtatatggg 234060 tttaataatt ctaatggagt gtataaagct gtatcactta catctttttt attaccatca 234120 gtataaccac gagtagattt aatctgtgta tcatatgaaa gttgtctaac tattcccacc 234180 ttattagaat cgggagtaga tattcctaat ataccttgca tactttcgtc ataagaacga 234240 atatcaggtt catatgattg ttcagagtta cgtccagcag gacctttaaa tgtaacagaa 234300 gtcatcttat ctatttctaa gttagggttt aaatcagaaa cttcatctac tgtaggttgt 234360 tccataatag ttttaattaa ttggtcttgt ttaactgaaa tattcttagg atttttatta 234420 ttataagaat ctgaatattc tttataagca tttgccatca ttttatacaa taatgcgtta 234480 atttgctctg gtccacgtac acgataaatt cccatatcat tatgatctct agctgaaacg 234540 tcttctaaca ttgtattagc taatagtaat aattcaacca tattatcagg aagttttaaa 234600 tctcttaata cttctttagt aataggatcc attgctaaat ccatagtatt tttaatacct 234660 ttaccaacat tacgactgta gaatttatca ttgaaatatt ctaagtaagg tgtttcagtt 234720 tcaaaatcac tgaaattgta ttgtgaagta ggtaatacag ttaatccaga cattaataaa 234780 tcaaatctta atttatcagt agagtatatt aaataaccgt cttggaattt aatcttattc 234840 tttttatcat gaatgctaat tctttcattc tcagtagtaa atttataatc aacttcataa 234900 agatcaagaa tattagttaa acctttatag aaacctaata atagaattgt aggtactaat 234960 ttattagtaa ttttaacacg tgaaaatgcc atcgtcttat tagattgaat attcttactg 235020 aatttcttat caataactcc aaagtcaact tcattatcta gtttatcaat aatgtaatca 235080 aatattatta cttccataga tttaatatta gatttactac attcatacat aacagattct 235140 gttttgtctg ctaatattaa tttagattta ttaatattat acccgatagg gaaatattta 235200 tcttgatcat aatcaatctt agataaacta gcactatcag aaatcattcc taataaactt 235260 ctttggttga attcaagtac attagtgcca tcttggaaat ttaatatatt tctagataaa 235320 ctattataaa taactgaagt tacgtattta ttattaatta aagaagcatt acctttttta 235380 acagataggt tagatttatt ttcaatataa tctataactt ggtcatcttc aataactttc 235440 ttaatccatt cagtttcagc attttcttta taaccgaatt tttctataat gaatttatta 235500 tagttagttg taatccaaac agtatcaggt ttatatttaa cgattggcca catcattaac 235560 tgtttagtta atactttttt accgccatta agtttcatat atttaccgtc aataacttta 235620 ggtacatcaa atttaacatt atgagttaaa ccatctggac ttctaaattg gactttaact 235680 gtatttttta atgactgact atctgaatta tcttcaatat tcattttatt aataaatact 235740 ggaatatctt cattgtcatt aaagcttttc attatatcaa taaagtcttt attaaatgtt 235800 ttttgcatat aagaaatatc aaaatcatta gaagcaatat tgttaatagt ctcttcattg 235860 atattattaa tattttcatt aatttctcta tcgattaatt tatcttcaga aaaactaaaa 235920 tcttctaaat cattaaggta ttcatcttgt ttcttagata aagctaatat ctttttagta 235980 tttttaagag cttcatcacc aatactagat ttatttttaa tatttctctt aattgattta 236040 aatgaatcat tcttgtctaa tacgtctgaa tataaagttt cagtatcaat atcaattaaa 236100 tctttattat catttaattc tttttcaatt atcatagcta tattatattc atcatcaaca 236160 tccatttcag tattgtctaa tgatctaata taacttattg tagaatctat tttattagat 236220 attttttcta gctgttcatc attttcatat tcaacttcat cattctgagc ttcaataggg 236280 tcaattgtac ctacattatc aaatgctttc tttttaatta ctccatctac agcttcagta 236340 ttatcatcat cttcaacttt actaatttca tcagtatcca atgcctgtgt attagtgtca 236400 atcattcttc ttaatctttg tctaagtctc atattaagtt tattataatc tttgtaatca 236460 aatttaaaca ttattccatt atctaatgag acaaataata aattaacatt ttgattttca 236520 ccatgaggta attcttcttg attcttaatc atcatgaata agcttgacat gaaatctttt 236580 gtattaggtc taatagcttg ttgagaaggt ttattatacc catcaacatt aatcacataa 236640 agtaaattat tgtaatcttc tgtattattt aaagagttaa aagttgattt aactgaatct 236700 aatactgtat taaagttttt agtcattaat gattatctt ctaaatcaat aaatttagtt 236760 gaatcaacaa tatagtttct acctttaaat aatttctcat ttcgttcaac tctatactgt 236820 ttataagatt tagatttaat ttctttttga taatctgtta tattcgttaa taatctagtt 236880 cttctatttt gagttctata caatcttggt gtatagatat tcttgaaatt ctgatgatat 236940 aataatccac tatttaagaa atcagtaaat gaattttctt taaaaccttt ataaataact 237000 aactggtctt ttttcttatc tttgatttct tcatcaatag ctttaatttt atatccagat 237060 attgaataga atttaagatt ttttaatcta ttaagatatt tcaattatgc cattcctttc 237120 cgtatttaat tttattgatt aatatattta tattactttt attttataat attattcaat 237180 aaatttccta tatacaatag ttttgattac tatcattatg tattttaatt ggatttataa 237240 aaataaaata acgaactatg tgagttattt ttaaatacat ttttatgaaa taaaaatgtg 237300 tactatcccc tcataatatt ttaatttata taaatatact ataagaatag tatatttatt 237360 attataatat tttattataa tataattata atattccgga cactttcaaa ttttttatca 237420 cataatggta caaatttata attttttaaa taattaatat aaaaatattt attaacttca 237480 tacatattgt ttaattatat aaaaattata aaatactcag taacatctaa atatcaataa 237540 aataatgaaa gaagtgaaaa taaattggct aatatgaatt atgaaaataa aacacttaat 237600 gaaaaagaag tatcgacatt attaagtgtt ggtaaagatg acattacatt agacaagtta 237660 aaagaattat ttgcttttag acaaaataca gaaccaatgt ataatccaac ggataaattt 237720 acattaaaga aagatctagt ctataataaa aaagatgaaa aaactactgt aggtagatat 237780 atatttaata aatttatttt agataataaa attggaccga ttataggcta tatgaatcgt 237840 gatatgggcg gttctggagt aggtaaactt caatctgatt tatcaaattt attacttaat 237900 gatattatta ctacacaaga aatgtcaaat tatatcgata aattacaatg gttaggtttc 237960 tctatagcca gttttattaa ttctagtcta actactacaa tgatgactgc tactgaaaaa 238020 gttaaacaga aaaaagaaga gttattagtt aaatatgaaa aagcattgaa tactcctgga 238080 gaggaattaa atgcaatatc agttattgaa aaagaattaa tcaatttaag taaagaagaa 238140 ttaaaaggtt tagctgattt agatatttat gatagtggtt cacgtggttc attcggcaat 238200 aattataaat taactgcatt aattcgtgga gcaaataaaa actttgctga tccaagtaaa 238260 attagaattg ctaaaagctc actagctgaa ggaattgatc ctaatgaact ttatatgttt 238320 ggagatatta tgactgcagg ttcagctgga cgtgcactag gtactcaaga aggagggtat 238380 caggctaagc aactaatgtc ggccttccaa acaactgttt tagataaaaa aggttctgac 238440 tgtagaacaa atcatttcct taaattaata ttagataaat caaacgcatc attaatgatg 238500 tatagatatt ttaaagataa taacgcaaga tcaggtcaat tagttttatt aactcctgaa 238560 aatgtagatg attacatggg tagagtttta gaatttagaa gtcctatgta ttgtgcaagt 238620 gaagatattt gtagtaaatg tgcaggagaa ttaccatata aattaggaat tgaaaatatt 238680 ggtctattag ttaaccaagt tgctcaagca atcgtaacaa gttcaatgaa atctttccat 238740 gatatgacga ttaaacaaaa tgaaatagat atagaaagtt atatagaata acatagatag 238800 gataacaatc attaaattga ttgttatcct tattttattg gattaaatcg ttctttaaat 238860 ttatattata attatgaggt gaatgatatg tattaatgtg atatacttat aattataaaa 238920 ataaatttaa tggagatgaa atggataatg ttaggtaaag aaataatgag aagatctgaa 238980 ataatttacg atgatacaga tataaaaact gttttaaatt tagatccgga taaagattac 239040 ataaatgaag aagaggatat cgaatatatc tgtcctaaac atggtaaaca aaaaagaaaa 239100 ataaaacaac atttagaaaa gaaaggttgt ttcgagtgtc aatacgataa taagtctaaa 239160 aagactaaag gtaaagattt attagaagag ttttacaaaa gatttagaga agatgttttt 239220 gattatccag atatagaaga agatcgtgta tattcatcta gagaagaaat aaagatagtt 239280 tgttttaaac atggagagtt cactagacaa attagagaac ataatacaaa agctaaaata 239340 tgtgataaat gtaaattaga ggatggagga aaagatttta aaaagaaaca atttgaagaa 239400 agattgagaa atgaaaatta tgaaatgtat aagattaccg atttttctga gactgtattt 239460 gaagggttaa ctaattttat gtatgttaga tgtaaaaaac atgatacgat taacaaaata 239520 caacctagat cattactaag taagaatagt aatgggtgtt caaaatgtag aagtgaaaaa 239580 ctattaaaaa gtagaagatc taataacaag gtatataacg tggaagatat ttttaacata 239640 tataaacaaa aaggaaatct tttaaatact gcgactaaat atcttgaaaa tttaaatctc 239700 gaacaaagaa aagagttatt cttaatgata tccaaacata attttggaaa taagtatgac 239760 tattctttaa tagaaaaaga aaaaaataat tttaaatcta gagataaagt aacactaata 239820 tgtaaagaac ataatgtcga atttaaacaa aatatatcac accactataa aggtaggtta 239880 ggttgtgata agtgtaaaaa ggataatgtg tctaaaagta tatctgactc atacagattt 239940 tctaaaagaa cagatataaa acctgaagaa ttaataaaag aagtggataa tgaaaatttc 240000 aaagataatg agataagaaa aatagtgaga ttaatgaatt ttgaagataa aggaaaatat 240060 tacagattat tagggaaaaa gattaaggga gataaatata actatgataa attagtgtat 240120 aacggtgata gtgttcaggt aactataaca tgtaaaaaac atggagattt taaacaggta 240180 atatacgatc actttttcca agatcataat tgtaataaat gttcaaagat cgtatccaaa 240240 caagaactta aattaagtaa tgatttggaa aaatatttta cagttaaaaa ttctttaaga 240300 agaatatttg aggataaaag aaaagaaatt gatatattta tcaaagatat taatttaggt 240360 atagagataa atggtctaag atggcattca aatgatataa aaaaggagga tgaaaataat 240420 tttgcaagat accatcaatt tagtaaaatg aatgaatctg aatgtttagg tataaaatta 240480 ttaaacttct atgacgatga aataaatata aagaaaaatg aaatttctta ttctaaaata 240540 atgaaagaaa ttttattatt taataattcc tttaatatta aaaatataga tttaaaagat 240600 ttagagatga aaaagatatc ttataatttc ataaagaaat tttataagaa acattcacta 240660 gaattcttta atgaagaaga taaaaattat agaggaatat tctataaagg ttatatagtt 240720 tccgtattct catttaataa taagaacgaa tgtcataact atagcacgaa ttacaattta 240780 aatgaagata ttgatttaat attagatgct taccctaata ccatttttaa tcttagatca 240840 gattcttata atagatataa atttcaagat tatgggttca ttacaataaa taaaactcta 240900 ccgcaatata gaaatttcaa taaaaaaggt ttaactaaaa atagatataa aagattagaa 240960 aagagggata ctaataatcc taatagaatt tatgattgtg gtagaactat catgatttac 241020 taatataata cagtgacatt aatttgtcac tgtattataa ttattttttt tttttattta 241080 ggatttataa ataactattt taatatagta atagatatat ttctatttac tatattcgta 241140 aattcttttt cttactcaat ctcgtaattt gttttgcgtc aagcaagtta catgggcctc 241200 ctacccgtat aatattgtac tacacctaag tggatcatag aaaatggtcc actttgttta 241260 tcattgtccc atagctcaac ggtagagcga tcggctgtta accggtttgt tgaaagttcg 241320 aatctttctg ggacagctta tgttcttgtt gctactggtt aaagcatatc gagtaaatcg 241380 gtattttgtg agttcgactc tcaccaagaa cacgccaata ggattaatca tccttacact 241440 aaggctgcag acttagtgtg aataaaatac agtatgagtt atatgccact cttatactgt 241500 tagattcaac taatgctaag gcatatcatt agttgtaaaa atttaaaact tatatctaat 241560 ttacgtttag ttattagatt gtatttttgt taaagaggac ttattttact taattgtaat 241620 aagtatctga ctttaactta attggttttc tagttttgac cctaacaata aaaaactaga 241680 ctattaata ttttatttct ttttagctca caacttaaaa gaaaaactag gtggatcatt 241740 ttatgctttt ttgatcggct aaaaactaat aaagcaccct taccctaacc tcattaattt 241800 gaaggtttagg gttattttat acatagtttt aaatatatat tataaaaatg agatataatt 241860 ctctcaaata cttttataat atggagatga aaaagatatg ataggttcaa agattagaaa 241920 atcattaaat gaaaaatttg gttatcatta taagttttta ttagaagatt ttaagaaaga 241980 ttatgattta aataatgata caattatggt aactaaagaa gctagtgaca tcacaaaaga 242040 atataaaata aaatcattaa agtatactaa agacattgaa aaattagaca aagactttaa 242100 gaaagaggaa gaagaattaa atattagaaa atctagaatt tttaatttag atgaattagg 242160 tttagatgaa gaccttagaa acatctgtaa gtatatagac agcactacta aattaaaagt 242220 aaaagttaga gagtataaaa aagaaagtaa agaaaatatt gaattctttt acaaaaattt 242280 tgctaattat acttataata gtgtaatata tgatatgagt cagtttaagc catcaacaat 242340 tagatctaac cagaaagtta tatgtagaaa acatggacct ttctttacca ctccagtaga 242400 tttctttata aagaaaaaag gatgtccggt gtgtgaaaaa gaaacggaag aagaaaagaa 242460 agatactagt tggaaggatg aattcataga aaataaaaat gaaaaaatat atcaagaagt 242520 aaaggaagag aaagaaaagg aaaataaaaa atctaaaaaa gaaaaggtag atgtgaaaaa 242580 agaaaataaa aaacttttag atgaagtatt aaatccacct gaattaggat attatagaga 242640 accggataag atacctaata ctgaaaaaga aaatgagaga ttcttgaaga gtattaaaga 242700 aatagatagt aaatttgaag aacctaaaga agttgaagaa ccaaaggaaa ttgttaaacc 242760 taaattaaat aaaaagacag ttgatcaaat aataggagac gataatacta atctaagcag 242820 aaaaattaga tatataaata aaaatattta tacagaaaat gaaagacaag atttctataa 242880 aaaattaact gaccgcaaac atggtaaaaa taaatataag attgataaat ttagacctaa 242940 gacgattaaa gaaaaacaag aagtaatttg tcttaagcat ggtcctttta aagtaacagc 243000 tgaagaatta ttaattaaag gtagacagtg tcctaaatgt tcttctacta gtacttccat 243060 aacagaaact tttgtaagag aatatattca gagtttagat tttgaagtta ataattatga 243120 gatagaagat ttaatcaaac cttatggtgt tgatatagtt atcgaaaatt taaaattagc 243180 tattgaagtt caaggtatta aatatcattc atctgaaaca cgatcagagg cttcaaataa 243240 atatcatcaa ttaagaaaat taaaaatgct agaaaataaa ggttatcgtt tattgaatat 243300 atacgatgat gaaattccta ataagaataa aggaattggt tgggataaat ttggtagatt 243360 cttatctgaa ttaatgatgt ttgataaaag atttgatatt gaagaaatgg atactaattc 243420 aataaaaata gatacaatta gttattacaa attcagagaa ttctttgaaa actctagaca 243480 agaatttgtt actggtgata cagaatataa aggagtggtt tataagaata aattaatttc 243540 agtattctct tataataaag aaacacgaga atgtcataac tatcatacta tgacaaataa 243600 taaatttgat ttagaattaa ttaatagaaa atacaaagat ttaaaattta tagttaaaag 243660 agattcttat gtagcgtata aaatgaaaag ccatgatatg ttaccaatag cagaaacgga 243720 acctgatttc tgtaactttt caaagactaa tggaaataga aaaaataact atataagaca 243780 aaaaagaaag gatgaaaatg ataaaaacaa agtatataac tgtggaaata taatttttgt 243840 attttaaata ataaccctaa ccttattaat ttaaggttag ggtattttat attttttttt 243900 attgaattat cttatttggt ttaacttcac ttttcatttt gatttcagtt ttaactttgt 243960 caagaacttc tgattcatat aaagaaggat cttcttcata ttttttagtc atcttcttaa 244020 cagcttctaa tttattttct aatggtgctt ctaattctac ttgattaaat aacccttcaa 244080 aattaccgaa aacaaattct tcatttaatg gaataaacag atctccattg tgtgctaact 244140 catgagcagt ataagacaaa ggtacaattc ctatattacc ctcaaaatgc attttaataa 244200 cgtcttcagc tattttaaaa ctttcatatg attttttata ctcataatta gttttaagtt 244260 tttctctgta gctagacact atatcatata aagacaatgg gtagtggtgc atttccatag 244320 ttaatcgctt atcatcattt atatcaactt ctggtataaa tttacattta gtgaggtcca 244380 tttcagtttt caaagcttta ataaatgatt tgtattcata tgagcttcta actatttttt 244440 caatatattt attaaatgtc tcttcagact ttatatcatc ttcattatta tacatttcga 244500 atttctttgt ttcatctaca tttaattcta ttgtttcgat taattttgga aggtcttttt 244560 tatctacttt tggcatttgc atagatttaa taccttcttt ccaattttct tttatctata 244620 ttaatataat taaatgttat gaatattttt tagcctttat gcgtttcatg caaattttta 244680 aatatatatt ataaaagtga agtactaatt agctaatagt atttcataaa aattacacta 244740 ggagagtgaa tcggatatga gtagaataat actaaagaaa aacaacttgt cagaagaaaa 244800 tatcagttta aaggaggtta aacgttggtt taagaaagaa atagatttta atcaaccatc 244860 taaaatgata aatgataaaa attatgtaaa taatgtaaat aatctttttg atggtgttat 244920 taatattatg aaagaaaata aaataacaga tacaatgttt agatttattt ccaatgataa 244980 taatgaagat attagaaata tttttattat ttattcaatt gatagtattc cttttgttac 245040 tagagtatat ggaccaaaaa tgaatcttaa agataaaaat agtgatgtaa atgtagatgc 245100 attactaaaa tttattaaat caagtatcat tgacaattta atgatttaca aattttataa 245160 aactacagat tttagtttcc ataaaaaact aagcagtttc ggtaattatg aaagaaatac 245220 attatacgat ttaattgctg aaattaataa agattctatt attgcagcat ataaagaatt 245280 aagtgtagat aatttaggta gttatttaat ttcattagac aatgaggagc tactaaataa 245340 atcttatgac gcaattaatt attttgattt actaatggat gctaatataa atgttagaag 245400 taaagaaggt aaattgattc aaaagattga cagaaatgat atattttcaa atagaacata 245460 ttctgaagtg ttcacattta gtcaacgttc agattattat ttcgctagta atccattatt 245520 caatattcca aaagtaagtg atgtaaggga tgatactaga gtagatttat ttatatgtac 245580 aaatggaaaa gaacaaaaaa taagagatac aagtgtctta actagagaaa atttatattt 245640 caatccattt agacaacgat tcttgtcagt tagctatgaa catcctatta gagagacatt 245700 aatatatgat ttattcttaa gtttcttcgg tatagaaaat attgaaaata ctttaaaaag 245760 atttacattt gaacttcttc aaggtgttta ttcaggaata tattctaaag ggaatgttaa 245820 tgaagttact tcaaaatcat atttattaaa ttcagaaaat aaacgtggat atactaagaa 245880 gaagaaaaat gagtatccat taaaaatgaa catatcagaa acgttaagca ctagtactca 245940 tatagtagga tatactttat tcaataactt cttatttgaa tatatacaat caagtaataa 246000 aactataaaa cttgatgatt tcaatgttat aaaattaatg aaattcatta cttttgaaaa 246060 taataacact gattttaatg aagatattaa aaatgtcttt acgtcaagaa aagatatatt 246120 taatggtaat aaacgtatta atacatcttc gcatagatat acaaatctaa aactaggttt 246180 agaatcttca ttaaatacaa tatttaatga ggataaaaat tatattgatg catttactaa 246240 tcaatatcaa aatataattg aaggaaaata tgcattttct aaacctgaaa aagaaagtat 246300 tattgaaatc aataatgaag atgaattaaa agaaatgcag gaagaaatta aatcaaaaga 246360 ttctaatata gaatatgtag aagaaactaa aaatgataaa aaagaggaga aattaaatat 246420 gtcatatcaa attattaaag aaaataaatt tactaaggat gtatcattta aatatgcagg 246480 ttctacgcat agaattgata aaattcgtaa aggtgatatt gaattagaaa ttgctaaacg 246540 taaattattc attaataaat taattaatga taatactaaa tttgctttcg tagatagcgt 246600 agagttctcg gatagtcata ctattaaagt tactaatatt gatggtgaag ttcaatttgt 246660 tagtgattat gttgatgttc ttgaaggtac agatacttta gaagaaatta gaattaaagt 246720 tactaataaa gatttagata gtgatgaaaa tttagttaaa ttaattactg gtgaagaaac 246780 tgatgttaat tctttagatg aagaaatctt agattcattc atggtttaat aaaattaata 246840 aatgctaaaa actttttagt tatctatta aatgaagaga gttcaaatac tctcttcttt 246900 attttttttt ataactttta gggatgtgaa taagattgat agactttaaa aaaatgctta 246960 aagagaattc taggaacata gaaatttatt gtgatggagc aattaaaggt gttagatcaa 247020 aaggaactaa atatggtggt attggaatta ttccagttca agaagattta tttgattatc 247080 tatctatacc ttacatagga gaagatctaa ctaataataa attagaaatt ttggctgtac 247140 tattcactat attattctca ttagaagttt ctcaagatta taaaggtaaa acaaatatta 247200 atataaagtc tgatagtgaa tatactgttg atggatataa tacaaattta gataaatgga 247260 taaataaagg atggaaaaac tattcaggtg ctgaagttaa gaataaagaa ttatggcagt 247320 taatggaaag aattaaatat tatttaaata gaaacagaaa taagtattat gtaaatttac 247380 aatggactaa aggacatgat aatgaaaaat ataatgaatt agcagacgaa tatgcggtta 247440 aagctaaaat ggaagcatat gaagacaatg atagtgcttt ttctatagat tatgctattg 247500 ataaagctga taaatttata actaaattag aaaagaaaga ggtattgtaa atggcaacta 247560 aaatagattt taataatgaa gacgattata atgatgtatt aaatataaat gattggaaca 247620 ggctatgtat ggacttctgt attagatctg ctagtattag taaatgtgct gccaaacaag 247680 ttagttcaat tgtagctgat aaagattcta tattctctct tggagtaaat ggttcttttc 247740 cgggtaaact aaattgtaat gaaatattta aaaaagaaga tggaatttgg tacgtaaaag 247800 atcttaatga agaaactaat ttaattgaat gggttaaatg tgaagatcaa gaacaacatc 247860 ataaatggtc tttattaaat gaagttcatg ctgaaataaa tgctttatct aaaatgaata 247920 aaaaaggtat ttctactgaa gggttagact tatattgtac tcactcacca tgttataatt 247980 gtgctaaaag tataattgct gctggaatta aaaatgtcta ttttaatgaa ttatatgatg 248040 gttatgaaga tgttatggaa ttattagttt caaataatgt taacttcatt aaagtggagg 248100 tctagaatta tgtcttggtt acctctatca atatttatat ttataggaat attacttatt 248160 ttatcaacaa atgaaacaaa aagaatggta agaactgaaa aattgaaaga agaaaaagat 248220 tattaaaaa gacaaagatt taataattta aggactagtc aaagaaagcg aggaaaaagt 248280 agatgttaga taatgtaatt atacttagtg ctttatccat agcattcttt ttaactactt 248340 taacatttat atttctaaca attcatttta gaaaagaatt agttaaaaat gttaaaatga 248400 ataaaaatta tagagataaa atagctattt tagaaaagca aacaactgga aaagatgtac 248460 tagattcatt aaattctatg atcgatgagt ttttaaaacc tacttatgat ttaactatag 248520 aagaaacata catggattta aaattagaca atcctctagt ttcaactaga aatataacta 248580 tatctgaaca aagaaaaaat gttatacttg aagatgtatt tgagaaattc atgaattatt 248640 tatccgatga ttttaaaaat aaattgtctt taatatataa ggaagatgaa atagaaaata 248700 ttgtactaga tataatgtac tataaattaa ctgtatatat taaagaacgt aacgagctac 248760 aaaaaaattc ttaaaaatat cccctaacct tattaattta aggttagggg tttatattat 248820 tttttttata ataaaacatt tattaaatct gttaaaaatc tcaattgatt tttataagat 248880 aaatcttcaa ttcttacttc ttcatcaata tcatcttcaa tatacatttc caatgtatcc 248940 atttcaatga tatatttatt ttcaattata tctttataat aaccagaagt taaattataa 249000 ttaatcatat tatctttaaa taataaaagt ttcttataca aatccatttt atctttcttt 249060 ttatcttccc aaagacactc tattaaaaat ttaaacatgt aatccatatg atgttcctta 249120 acaccatttt gataaccttt tacatctatt ttattttgat ataagtttat atagtgttct 249180 ttacctaata catttatata attatcatac tcttcacttt cagcaaatct aacatgtttt 249240 gatatcttta aattattaca tttcttacca ataacaaata tagcatcttt tttaatactt 249300 aaaatatcac tatctttaag attattattc tctataaaga tttttctagc tatcttaaaa 249360 ccattcatta aaacttcatt cattttttta ttacttctca acattttacc aataataaca 249420 tttctttcat atttctgagt atttcttaat ttattatatt gttcttcatt aagataacct 249480 gaatcatata atatattcat accagctgat ttaatatcat attcagtaat tacagtatct 249540 ttaatatatc ttacgtctga tgtgtaatta gttttcatgt ataaattaga cactgcaatt 249600 acctcctcta taatatttta ataaaccaat tactatttaa aaatacatta gctaagcaat 249660 tcatttataa tcctcctata taatcatcgc cagcctcttt actaatttca tattctctct 249720 caatatcttc ttctgattta ccttgtaatc cttctgcaac ttcaccatat tcatcaagta 249780 aaaaatctaa aaatcccatt ataaaacctc ctcaaaattg taatctaatt atcttcgtaa 249840 attttaattc ttaacaaagt tatgtttcat caatgtctta ataaattctt tattagttaa 249900 ccaatctcca gtattattaa ctacttcaag atcagttact tcatctaaat ctttcttttc 249960 tttctctaaa tcttctttat ttcttccttc acgtttaact tgattctttt cattaactac 250020 ttgaatagta ataatgtcag aatcttcacc atatttctct ttaatatctc ttacagaagc 250080 atctctacct tctctattta caataataat atttacatta taaataccat tttgcggata 250140 ttctaaactt tgatcaattg taccgtaata attttcatag aaattagtct tagctatta 250200 attacctttc ataccatcat attcttcttt atttaagaat acataatcta ctccattttt 250260 ctcatcttct ctttgctttc tagtagttac ttgatctaat tttttaaaga ataaatgcgg 250320 atattccttt tgatctgata aattatttgc caatacagtt tttcctgaac ctgatacacc 250380 acataataag ataaattttt tcataactag aaacgacctc caaattttat tatctaatat 250440 tatttggttt tctatatttt ttagaaaaat tcgttataaa ttatgattta attccatcag 250500 attctcttaa tttatcaatt aattctataa attcattgta tttcttatct acaattttaa 250560 gataattata ttgagaatta gaagcaactt catctttttt cttttctttt aattcatcac 250620 gtttttggta gtgattattt ttacctttaa tttctattaa taaattaaaa tcaggaagat 250680 aaaaatcagg catgtagaaa tgtttcttat tagcaaacgt ataaggaata gctatattag 250740 aaggagataa tacattatta gattaagaaaat ccatttgttt atctaagaat tctaagaaat 250800 ctttttcata agatccgaca tattgagtag gtaaaccttt gccagaactc caatgatatt 250860 tgcctgaaat tcttctattt tctaacattt tattttgcat ttcagggtca tttaataaag 250920 tagtcttacc gtatttttta ttcattctat ctttaaattg ttgtctatat ttatctttac 250980 atactttatc atgtacacgt tcatactttt cagtttgttc attaaattta gtaggtttac 251040 cgcatataat gcacgtacca tgagttttct tatttctgaa attaaaatat acattagctg 251100 cagataattc acctaattct ttttcatgaa atttctccat atgattataa agaccttttt 251160 tatctacata tttctttgta cagaatggac atttatgata ttttgtagcc attattaatt 251220 ttcaccgttc tttcattatc attatttaag tataaatgct tgtttctatt gttttgttat 251280 aaaaaattaa gaacgcattt atttataaat ataatattat atagtacatt aattgaaagt 251340 tggtgatagc taatcgctaa taaaaagaaa cattttagaa atgaaatatt catggctcaa 251400 aatatctata atcgtcaaca tatgttagaa gatatggaag ctatgggtca aacaatccag 251460 aatttaatta taatgaaaaa aggaacttat cctaatactc caaatttagg agtaggaata 251520 gaagattatt tatttgaaat actagataac gaaactatat ctgatattac tagtaatatt 251580 aataatcaga taagtcaata tatagtatct tcttctgtta atatagatgt taaagtaata 251640 caattaaaaa atagtaatgc aaatttaaat agtttaaaaa ttgacgttac attatcagat 251700 acaattgata tttctaacgt acaaagtttt tcttatgtgt ttgcggctaa tatgttaact 251760 aggaaaatgg taactaaact tgtcttaagc taagacttta aaaataataa aagaaaagaa 251820 tggagaaata gataaatggt aaaaaaagca gataacaatg aacttaatga ttttatgtct 251880 gaagaagaat taaatgaagt tagtcaaggt tcttctaata atgatgagaa acaagaacag 251940 aaacaaagta ctcaaaaaca acaacataat aaaaataatc aaggtaataa aaagaaaaat 252000 aacaatcgca gaagaaataa taataataaa cataatcaac aagataagaa acaaaatcaa 252060 aatagcaaat cagcaattcc aactcaaaga aacaaagaca atcaaactat gatgagtgct 252120 agtgttgata gtgataatca acaagaacaa gctaaaacag atcatatcaa tccagaaggt 252180 cctcaaccag gcgaaggttt tgttgactat gaaaacttaa cttcatatgg atttaatgaa 252240 ggaaaatcaa atgaagatac ttctagcatg acattatctg attttgaaga acaacaagaa 252300 caaaaagcta aaaaagatta tgaaaatcaa aaagctatta gtgaaattga aagtattagc 252360 agtgatgaaa gagctaatct attaaataat attaatgtag atttagataa tattgaaatt 252420 atttctgaca ttgattatga tattgataaa gaaaacacta atttcgtatt aaatagtaaa 252480 gcaactcatc aagttgtatt accacaatca gcatacattg ctcatatgga aagtttacgt 252540 aaccaagaga ttttatctat tgctgaatct attgatgatg attacaatgc aatgttaaaa 252600 cgttaccaat tatacttcca caaaatgaat acaaattcat taggaattaa taacttccaa 252660 gatttcgcta gattaacttc tgtatatgat gttagtacta ttgaatacgg attatacaat 252720 atttcattcc ctggtgaaac taaatttgat attagatgtg gtagctgtaa agctgaatta 252780 aaagacgtta aagtttctaa tgatcaatta atgtcattta aagatgaaga tgctttcgat 252840 catgttacta aaaatgttaa gaatatcact agtgttgatg aaaataaaga acactcatta 252900 atttatactg aacaacgtat tgctttaaga gattctaaaa ttatctttga aattgtaaca 252960 cctactattg aaaaacactt aagagtttta ggtagtatcc atatggacgg tttaactgaa 253020 gatgaatcag aaagatttaa acaaaatgcc acagctttaa tgcatgttaa aaatgtttat 253080 atccctgact taaaaacact taaagaagga caaaaaccta agttccgtaa attaagtgaa 253140 gataacatga aagataaaat gaaaattatt gaaaatcttt ctattcgtga tggacatcaa 253200 ttaactgatg ctatttatga tcgtgttaat aaacatgcta ttgaatatgc tattaaaggt 253260 gcaaactgtc ctaattgtgg agaagattta ggtaagattg atattgacat gagtgaaatg 253320 ctttttcggg aagcgctgca tttggtttag taacaacgac caactccaag cagtatagaa 253380 aaaaggtctt tgatgatgca gcgtatatag catatttgct tgatttattt gaaggacgtt 253440 tatcttttaa tgaaattctt aatatggaat taaatatatt aaattctatg gttaaagcca 253500 aagaaaaaga aatgaaaaat aaacgtatgc aacaacaaaa attagaatct gctcaaagaa 253560 gagattttaa taatggaatg cctaaagtag aactaccaag acatttaaat aattaaaaaa 253620 gaaatgaaag gagctgacta ttgattggtt actaatacta aagatagtca gaaaatcctt 253680 catatttatg attctcttgt tgaagatgat gataatattt tatcatctct atgtcattct 253740 aataaaggtt tagtatttgt aaatctttta tatgacctag attataaaat taaagaagga 253800 ttttctaaga actataatga atttgattac attattttgg aaacagaaga taaagaaaaa 253860 ttaaaagaaa aagtttcata tataaaaaat ttaaaatttg aagacaacaa gaatagtata 253920 agaatttcaa ttgtataaag tgaggtctaa aaagaatgtt agataagaat aaagaaaaga 253980 agaaattagt ttcaaatatt gtagatgaag attcatataa agatatagct gaattaacta 254040 ttgatactat ttcaaatacg ttaatgaaat cattaggtta tttcggatct acaactattt 254100 ttgatgatgg tattagtaga tatgtaacta aagacggtta taatatccta aaaaatatta 254160 gatttcaaga tacaatcgct acagctattt tgaattttat taaagaagta tcgttatcat 254220 tagttaaatc agtgggagat ggatcaactt catcagtaat taactcacaa gctatgttta 254280 aagaaattaa taaaagacta aaagaaaaag atgatttagg tggatattct cgtaaagaaa 254340 tttctgattc attaaataat atgaaagaat taatttctaa agaattaact tcaaaatcta 254400 ctaaaattga tcaagataat ttccataaat taaaaaatat cgctacagta tctaataaca 254460 atgatgaaaa attaggagaa atggtttatg aaattttctc taaaattggt aataaaggtt 254520 ttatattccc tgaagtttct gataatgaag aagaccatta ttcattaact agaggtattg 254580 aaacaccaca tgcattatta gataataaat taattaataa taaagatgat cattcagttg 254640 attttagtaa accttatgta gttgttgtta atgataaact aactgaagaa gatattgtat 254700 ggacatcaaa tattatttct aaaattaaac ctttctcagg acaaggatta atattctttg 254760 ctccagcttt ttctaaagag tttaaagatt atattaaaaa taatttacat gctaatagaa 254820 ataatggttc attacaagca gttgaaactg actttgaatt atctattggt tctcattatc 254880 atgatccaga aaaattagaa gatttagcta tatatacagg tggatctatt attgataaaa 254940 ctatggaaaa agaagatttc tataaacaag ttgagtctat tgtagaactt cctgaaaatg 255000 acccagaatg gttattattt aaagaaacgg taattggtag agctgaaaga attactattg 255060 ataattttaa aacacaaatt attaatggtt acggtaatgg tactcaaaaa cttaaagata 255120 gaatttcaga aattaataat gaaataactt attatactga tatgaattca gatcaagcta 255180 ttacagctat tactgattta caaaaacgag caaattcttt aaataatgct attgctaaat 255240 tatacgttgg tggttcttct caagcagaaa aaacttctag actatactta gtagaggatt 255300 cagtacatgc ttctaaatct gctttagaat acggttatgt atctggaggt aacttatcag 255360 taaataaagt tattaaaaat atcaatagag acgttttaag tgatttagat aatctgacat 255420 tagatttaat tgatatatct tcaagagaag tttatcataa agtattagaa aactttaata 255480 gatttagttc aggagaaatt gaatctatca ctcaaacttg tatagataaa gatgctatat 255540 tgaatattaa aaataatgaa tatgaagatg atgttaatac agatattatc aactcagtag 255600 aaacagatat caaaatatta gaaacaacta ttagtattat aggattgatt tcattaagta 255660 accaattctt aactaattca gtcattattc cacaataaaa cttattgccg aaaccatttg 255720 aacattaatg gtttcggctt atttttgtga atataattat cttaataatc ttttttacaa 255780 aattagattt ttatgatttt ttatttgctt ttttgctaat tttttgttat aattaaaaat 255840 atattaagca ggaggaatta tataaaattg actaatttta cagcttctca atttctcaaa 255900 aaccctacag gaaaaggttc agctacagta gctagacgtg atagaatcat attagatatg 255960 agaactagat tttcttatct ttataaaaag aatagaaaga attttaaatt aaaaatattc 256020 ttatatcaag ataaatacta tttctatttc caaatacctt cagaagatta ttttaaagag 256080 aatctatctt atgatgttat tattgaattt agaccaccta atgaaagagc agctaaagca 256140 aaagatctta ataattactt aataagattt attagtaatt cacctaactt tatgttcaca 256200 tatggttatt tatataataa agatgattta ctaataagtt ggttaagtta taaattagga 256260 cctaaagctt taaatcaacc tccagaagtt agaaacccta gacttgaata tggttttgag 256320 aaatcagttt attttgcact tttgtattta gagactaacc ctaaagcatt aaaaaatccg 256380 cttcatttga cattacctaa cagacaaaga attaaaagtt ctttcaaatc ttcagaatta 256440 aaattacgtg aatacaataa gattaaaaaa cagaaaaatg cttctaagaa aaactcatca 256500 ggtattaaaa gacaaataag taatcgtgtc gataaaagaa atgaagaaaa gaaaagagta 256560 actaaaccta ttaatagaaa agttaaacct ataggtaagg ttaaaaaagt taagaagact 256620 aactctataa aacgaaaatg atttattaaa tatattattat ataaatgata aataatactt 256680 atttatcata attattattt aaggagagtg cctgatattg gataaagtta aagaattaga 256740 gtacaaagag gatttagatt taaaaaagat tgatgaatta gttaataatg acgtggaagt 256800 acccctatta tctagtaatg tcaataagct taaaagagtc tctggtaatt ttgaattaac 256860 taatgaatac attaattcta aagacttaga tacacttgaa agaaaaaata aaaatggtaa 256920 aattgaattg gagtacatac agagaacaga tattctacca ttagttaaat ttattgaaag 256980 tgaaaagaat gatactatat ttatagattt caataagata ttagaaactg ataatcgtaa 257040 agtacctaag gatgaagagt ttgataatat atttactatt caaattaaac aaagatctta 257100 caagagtatt ttagattata ttgtaaatga tatgaatttt atagttaatg agattcctca 257160 cataatgatt aaaggtgcta ctatattaag taagatagct aaattaagag agaattataa 257220 agaagaagat ttcttcagag atattcagaa tattattgaa gatgaagatt taagaaatgt 257280 tattagaaat attgttgata ataactatac aattaattta gatcaaacta atgctgaagc 257340 tatgttacaa agtaagaaag ttattaagag agatttacag gtaactgacc aagtaaataa 257400 atcattctta tctacagctg taatgcaaag atttattatt ccgtttatta gtcaatatta 257460 tgtaactact aataagtatc attgtgaaaa ttctgatgca gataaggaaa gaactaaaaa 257520 cggttacttt aaagcattta attattgtat gtgtatttct tcattcgatt ataatgtaag 257580 taataataat aaactttata aaattgtaga acctaaagta attaaaacaa aatacaatga 257640 tagagttatt tggagattct tagatttacg ttcaattgac cctgacactg ttattaataa 257700 aataatggat aaaatcatta gacaaattgt atgtaaatta ttagtagata cttctgcagt 257760 atcttacttt acgtctgtta ttaaattctc aatcgattat gaattccagt acaaatatcc 257820 aattaagttt agatcaatac gtctatctac agatgatgac gatgatgaag atagcttcga 257880 taaattccaa atgaataact tccataaagt taatgaacgt ttagatttag ctaataaaat 257940 cactattgat agatttatta atgaacgttt agaagaatta aatattagtg atgattacat 258000 taatcgttta tatgataaat ttgattatat taatgactta caatctcatt taattaaagt 258060 ttattttgct gaatacttta acgttaatac aaatgataga aagagcattg tttcattact 258120 ggctattatg tctaaagaac ttattgataa taatatggaa actttaggaa aaatagtagc 258180 aagtaaagtt gtttcaggta caaaagctaa aaatgtaggc aaattatcat tagacgtaat 258240 tgcagataaa tattatattg ctgcttggga taaatataga tttatcaatg atattactga 258300 aaaagataac tttatcttac gtatagcatt agtaaatggt tattcattta actttactcc 258360 tgaagataaa gaagaagatg aagaagttat tgctgatatt gataagaaat actttatctc 258420 tgaagtatca caatttattt ctcaatacta aaaaaaaaat attaaaaatt acccatacac 258480 tctatattaa tgagtgtatg ggtatattat ttcttttttt cggatcatag aaaattttac 258540 ctatttaatt ctccttcaaa taaatagtct atattaatgt aagttctttc aaatatttct 258600 tcattaagtc ttttaatctc attaggatca ttaaaatcta ttatttgaga agataatata 258660 ttttgaattt tacttccatc aatttcatca actatatgag gatgattgaa tagtttaaac 258720 ctcttaatta gttcttctaa cttttcttct tttaattcat tttcaaatag ctttcttaaa 258780 gatgattcat tattatattc ttttaaagga gataatttta aatcagatat cattttatct 258840 aataatttta cagttgatac tggaccatag cttggaattg atttatattc ttgatcttta 258900 tgttccataa ataagttata taagtctaag atattataat ctatattaac aaaatcgtta 258960 atatcttttt tagtactaga gctaaataat tcgtctttaa tattctcttt agttattact 259020 ttactctttt ctgatccacg tagttctaat aataataatc tatctttata ttttaataac 259080 tgtctatata ttttatcgtt actaactatt aatgaataat catcatcatt ttcaatatta 259140 gttttagata atatataata aggtaatata gttggttcta ttttataagt gtctataaaa 259200 tatgcgttag gtatatattt aactatagtt ttaactaatt ctaaagttga tttaatagtc 259260 ttattagtat ctctataagt tatattgtct ttatccatct ttttataata ttctttctta 259320 tacccttcat caatattagt atgatatatt gactctttat ctgaatagaa taggaagaat 259380 ctactatgca tatttaatct actagcgaag aaatgtctat aatgccctat tatattaact 259440 aattcaacaa ctaaattcaa tctatcttta gtttttacgt gtgtaaaatt ttcagctatt 259500 tgaggtgaat ataattgttt aataactgaa tttaaatcta catatatagt tacattatca 259560 tttttagtat tactaccaaa tctacctcct tctacataag gtctaactaa ctcagtcatt 259620 ttgttataat ttaatttttt agagtttatt atacgttcta ttatactaat atccatatgt 259680 attccacatc ctttcattgt tataatatat aattatatat taattcgtaa ttttataaaa 259740 attgatatta cctagtaaca ttcacttata ataataagta tcgggaagtc ggtgaattaa 259800 aaattgatag aaagcttgat tactaaaaaa atatttaata taaaattaat agcattatat 259860 tcagatggaa ctactgatga tttatctcaa tttattaaaa gatctagaat agaaatgaac 259920 ttccaagaat atattatgcc atactataga tttatattaa gattgcctaa agagactata 259980 attaagatta ataaagatag agacaaagta gtattttctt tttcttcaga tatgattact 260040 actgatgctg aaagtgaaag tttatctgtc cctttttatg aagaaataat attaaaaccg 260100 ttaatggatt taagtaatcc agttaattat gatgatagag tgactagaac tgatgaagat 260160 caaaaacatt tatttgatag atatgagtta gttgctatat ctgaagaaac gttaaaaact 260220 aataaaccta tagtttcagg tatctataat aactgtactg tcagtgaagt agtcactgat 260280 ctattaagta atttaaaaaa tagagaaata tacttacacg aaatagataa taacaaaata 260340 tatgaacaga ttatattact tcctgcaaac gtatatgata atataaaatt tattgatgac 260400 gtatacggta tatataatag ggaaattaag atgtttaacc atgaaacagg attaaatatt 260460 ttaccaatgt ctggatttga tcctaatgag ataggtaaag ttaaagtaga aataagattt 260520 ccatcaaatc aaactgatga agaaatcata gaaggatctt acgagcaaat atctgaggaa 260580 gatgacttag ttagaaataa aaatatagta acaagaatta ataatgtatc tctagtagat 260640 aatacaagat tatttaatga attaatcggt tcagaaatta atttatttgg aatggataat 260700 gagacagaat acactaaatt aaatacatat cgtagagata tggaagatag aaatggacct 260760 attaataaag ttaaagtata tgacgatatt tatgataatc cttatagttt agaaaaagaa 260820 tttaataata gtaaagatat aatattaaag atacagttaa atgatatcga tttgactatg 260880 gaagatactt ttaagcaatt tgatatagag ttctttaatg aatattataa acactataac 260940 ggtttttatg aattattatc tattaatcaa gaatataaaa atgcaagtaa agctttagtc 261000 ttatcaaact atgttacatt aagaaagata actgatcata catttattaa gaatgataaa 261060 aataatccca atacctaaat gaattatagg tattgggata aattattaac cgatgtattt 261120 ttgaacatca tttaatacat ctacatgact cttcatagca ttattaatta cttttctata 261180 aagtacatta agtttattaa ggtcattaac cattctttgg ttttctctta ttttttcttc 261240 ttcaatttct ttattagcaa atttaattga agtctctgaa gcggatttca ttgtatctgc 261300 tgaaattttg aatgatttag cgaatgattt agcttcattg aattgttcaa aagatttatt 261360 aacgatataa tctaaatcaa tagacattgt taatggtatt tccaagtaat gatcgctttc 261420 ttctaattct ttttcaaagt cataatattt cattgagaaa ctatcatgac ctgcataatt 261480 taaagtattt tcatattttc ttaaattagc agctttccat atactaaata ctgaagctgg 261540 acctgaaagt ttactcatta cgttatttat ttgctcttta ttctttttaa ttttcttaag 261600 tgtagattta gttttaattg taactctgtt aaaattgtta ttaaagaatt tcataaattt 261660 aactaatcca ttcttaatta atgatagtat atttaagaaa aattctttaa cagtttgaaa 261720 gaaatcttta acaggcgatt cgtttagagt atttaattca ttattaaact ttaatgattc 261780 atttacaatt tcaatttctt cctttaagaa ttcattatta taatctttat tttctaacaa 261840 gaagaatctt tctcctttct ttattaaata aaaagaccta ataccctatt attaagagta 261900 ttaggtccta tatattatag aaatttatta tttttcagca gcagcttttt cttctttttt 261960 acctgcacta ttaatagctt tagcagcagt aaatgctgta gctaatgttt ggttagataa 262020 tttaacagct ttagatacag ctgtacgagc taatgaatgt gctttagaag catttccagc 262080 aacacgtttt ttctcagtga tagcttcttt atcaccttta gcagcagctg ttacgccttc 262140 ttttgcaaca cgttgagctt ctttattagt ttggtctact actttagcag cagctttaac 262200 ttcacgtact gaaccttcag cagcttgagc agctttagaa gcatcactaa tattagaaat 262260 agttccagaa actaaattct tttcatcagc aacacctgat ttagctcttt cgaaaccacg 262320 atcgaagttg ttaccatctg gtttagctaa ttcgtttaag tttttcaaag cagaaggtgc 262380 taataaagaa taacttttag cttcttcaag tttagcagaa gattaactc cagcgatata 262440 ttttttaaca tttaaagtac gagcttgtaa tttgttgaat gcttcaacga agaaagcagt 262500 gaattttttg aatgcttcag cgatagcttt agcgattttg atgaagaatt ctttagcttt 262560 ttgagcgtat tcttttaatt tgctagaacc ttgttcttca cctgcaacat cgtcttcagc 262620 ttcagtaagt acattaacac tttctagaac gaaaagttct gtttgagttg cttctaattc 262680 ctcttgtaga gaaacagttt caaatgattg attttgtaac attatataat ttcctccatt 262740 tattttataa tttaaatttt ttaatatcag aaactaatat taaaatcagt ttctaattct 262800 tttcctattt ctgcatctat ttgttctgat tctgatttac cttgaacttc agctactcca 262860 gaatcaatat caattttatc agctaattta tttaaacgtt cagtagcttt attttgtttt 262920 tcacgtgatc tatctgataa atcattattt tgttcacctt caatgatttt aacagcttca 262980 cgtaaatatt cagctatatc tgaacgagtt ttaattactt taatataagc ttgttttgtt 263040 aaatataaag ctagcataga acctgcaata accatatag aaatgctgcc gtatttaata 263100 gttttttctg acatttttaa gtatttatta tctttagctt ttttagctaa atctactata 263160 tcatcaaaac taaattcttc attagcactt acaaaagagc catcaaattt aaaaatttct 263220 ttaagctttc ctgctttata catttttaaa acattttcca aagtatttac ttctaaagaa 263280 tttttatttt taagtttttt accatcaaat tgtaatttac catcttcatt actaaatcct 263340 aagaagaata attgtgaagt taataacata actgttgatg ctaaagtagt ataaacgatt 263400 tgaccaactt cattaccatt attaaaacat tttttaaagt tatttttttc tttttcaagt 263460 aagtttacag aattctcaat agtatcaaaa acggaaataa gtttagggtc aaagctatta 263520 gatttttgac tttttatgta tttaaaagtc ttttcaaaat ctttataagc tttaaccttt 263580 ttaaaatcgc ctttactaga aaggatcgat tttaaatttt tatttccaga ttttttcaac 263640 attttttcag atgttttaga gattgcaacc gaaagagctt ccattttttc ttctggttct 263700 aatcttttaa aaggtctgaa tggtaaagag aattcctgta aaactctttg tgtcattgca 263760 tcttcagtta gaagatgttt tctttcaaga agttccacag ggaatctcca cttcctttct 263820 aggagttaat ccaaatataa taaaataata aatgaaacct acacgctaat ataaattttc 263880 attttatatt ttataaattt ttgttctaaa tataatttca ttaatttatt caaattaaga 263940 aatatatctt attatataat aactgtttct attaattaac gttttaataa tttttcaagc 264000 atttctgaag ttaaatcttt ttgattattc ttaactttgt aagcaccaag tttattttct 264060 ttaataactt caaatttgtt atgatctggt aaatatttat aaactaattc cctagtttgg 264120 tctaatataa taaaatctaa taagaagaat tcattataaa ttttcttagc agctctacgg 264180 tcagataata aatccacacc agttttacgt ttaacttcat tagcttcatc aatagtaatc 264240 attaaagctg ttgttggaat atagttagct ttagctgatt tagcaattcc tgaagcttta 264300 ttaacagagt agagagaatt taatttgttc caaatagaac cagaacgtcc ttttttagag 264360 tcttgtgcaa ttttcttaac tttatcagcg tccaataata aatctttaac tagacgtaat 264420 tcacctgtag taaatttaac taatttagtt actaagtttg agccacgaga tttatcagaa 264480 agatagaaaa tgatgtcttc agttttaaca acatgaacta ctgtcttaac accgaattta 264540 gtatccttct gaatataatt tgaagctgga agaggattac catttttatc tgcaggtaca 264600 tagttaattg tagttgttat cgtagtaggt aaagaagcat ttattttttc tttatctata 264660 gtaacttttg ctccaaaatt atctctttct gcatctttaa tagtagtagt aacttgacct 264720 ttataatctt cactgaattt tctttttaat tcagaatttt tttctatagt gtcgccatta 264780 cttgatttta atctaccgtc aaatactgaa tttatatttc tattagaact ttctgacata 264840 ttattaaatt taaattcttt ctctttacca tctttaaatt caagtatttc taaattataa 264900 gttttatttg tattctttga taattcaaaa tcatttatat caaatctaat atcatatttt 264960 acaccattgg cttttactgc ataaccgcta tttgattcat ttaatagttc tttcatttct 265020 tctctagtga tagtcatatc atttaaagaa ttcatattaa atttttcttc aggagtttct 265080 aataaataat cattggatct tttaatatcc tcttttgtac tttcagctaa atttacatta 265140 ttatgcaaat cagacataaa tgaagtagga tctttcggat caaaagtttg taacggtgaa 265200 ttcgttaata caaaatcaaa ctcaaaagct ctctctaatt ctaattggtt tctcattaat 265260 tcaactgtgt cttgttctat agtatcagat gtaactaaag gaaactgtag tataaaatct 265320 ccagatcttt gctttaatga tctttttctt ttgttattat ctttatagtt tttacttata 265380 cttgtaggat ttaaatcttt taaaagacct attacatccg taaataagtt tactttattg 265440 gccaatttat atttccgcct ttctttttct tattattttt ataaagatat gtttgatcat 265500 aagaaacaat aaaaaagtaa aaaaaaaaaa taaatttaga tatcgtatca attaagacac 265560 gatatctaaa tttttatgag tgagttattt ttgaatacct atcatattcg agaagtaatt 265620 ctttatttat aattagatag tatatgttca tttataaagt tgtctactcc ataaaaatgc 265680 cctttatcat ctatttcttt tattctattc tccaaatctt taattcttct ttctaaataa 265740 tcttcatctt tattcaattt ttgaatctct ccccatttat attactacta tttaatatat 265800 gacataaata tgtgtgaacg gactagccac cttaaatata atagatatga ctgttttgat 265860 tattgaccta atgtcatttg gtaatctttt tattgtttaa ctcactctgt tcacattttg 265920 ttattttata cttccactca ttctagtata gggggatcta aaacgaatcg gcatatttat 265980 atatcttagt agaatatagt gtattaatga gaagttaatt tcttaacttc tcacctttat 266040 aatatatatt taaaaattat ttacaaaaaa aaagaagaat cttgagattc ttctttatct 266100 ataaaaattt ggattagtca tactttctcg tatttgttct acaaactcat ccttcgagtc 266160 actaatgaca cgagcttttc cttttctttt ataaggatta gaaacagaaa tcgatacatc 266220 tttttcttta gctttgaaag atatcattga gttagcttca taaaatagtt tattatgatt 266280 cattctattt atatgtcccc aactataacc atttcttttt aaataatatt tggctttttg 266340 atagtcagac attacatctt tattaaattg ttctttatct aaaccttctt ctttcataaa 266400 attatctttt ttatttttta gttctttttc tttttcatta attttacgaa tttcttcttt 266460 ctttttctct tcttctattt ttattttttg aattctttct ctttctattt cttctgcttt 266520 tttaattctt attctttctc tttctatttc ttcttcaatt tttctttgtt ttttcatttt 266580 tctatcattt ctgatttctt taattttatt taacatacta tccatccttt attattttat 266640 ttattaatta aactaataat ccttttgaaa taattatttc aaaataaatt ctatcaaatt 266700 caggttctcc ttttttatta taaattacaa atgggtattt aatatctcta atatatccat 266760 tatcaagtaa atagctattt tccagtttca tctttttaat tttcttttct aatttatttc 266820 tactaaattt tgtcaaattt aaatcaaatt tataaaattg tgtgttacct gctgtatagt 266880 aaagattttc atatttatct attgcaaata attttccagt aaatcctaca actttcttag 266940 tttttgtttt tacatcttca atatttaaat attctaattc tctaccaatg caatttaatt 267000 ctttatcagc taaatcgtta aaatctttaa tataattatc tttctcttgt tttaaaattt 267060 tattaaaatc cataaagaca tcaattttaa atttttcatc ttcaaaaagt ttaaattctc 267120 ttacactatt ttctttttca attacagtta ttcttttact catattaatc catcctttta 267180 tttttttaat ttttcttcta gttcttttat tcgtttattt aaatacatag cttcttttat 267240 agtttctatt tttacatttt ctttcctagc tttatattca actaatgaat ttgcttctaa 267300 aaatatctta taattattca ttctttttaa atcggaccaa ttaaatccat ttcttaaaag 267360 atattgttta gcttcttggt aatcaatatt ttcagatcta tcaaaatatg atttaattag 267420 accttctttt tctaagaaag cttttgttgc tttttctcta gctttccttt cagattcaac 267480 tctttcatta aatttaagaa gttcttcttt ttctctctct tcttctttaa ttcttattct 267540 ttctctttct ttttcttctt taattctttt ttcttttgct tcttttctat tttgtctaaa 267600 taatacaatt tcctctaata acattaacat tttaaataca tcctttttat ttaaattagt 267660 tgattaataa ttatcaactt cataattata atataaattt ataaattaat ttattacgga 267720 aaatctactt taacatagtc ttattaaaaa taacgattgg tggtgtaaaa gagattggct 267780 gaagataaga aaactacgga agaaaagttt aaaaaagcat taaaagaaga aggagatata 267840 aaagaaataa aatcctttaa tccatataga atgaaagata aaaactcaga gatatttaat 267900 aaaggattac cttttatttt cataacagct cctagaataa atctagtaga cgaaaatata 267960 ggaagagaaa gtttctttct ttatttaaaa tcagttaaac ctgatttatt aaaaagctta 268020 aattttagta ataatggagc cttaagctca ggtagacctt tcatcccaat cctttcaaat 268080 agatttatgg gaatatctat tcccgataca caaacaacaa tgaaagaatt tcatgaaaca 268140 ttttacggtt ataaacaaca tttaccggta ggtacagtta attcagttgc tggtggagaa 268200 atagctgtag attttgaaga gaataaagaa atagacgtta tacacttaat taaagcctgg 268260 agtgattata tagaaggtgt gactagaggt tatctattcc cttcagatga tgctaaagat 268320 aaacgttata tagattatac tagttctata tattatttct tattagactt tgatggtgaa 268380 actgtattac attattctaa gtatactgga tgtttcccta taaatgtacc ttacgatata 268440 ttctcacaaa atattggtga tgatccagaa gttcctcacg tttctattaa ctttgcttat 268500 tcatataaag aagatatgaa tcccgatata ttagttgact ttaattcagt ttcaacaatg 268560 tctactagta tagctaatgc atctggaact gaacctatta gagctaatat taataatgca 268620 actatgggta taaaattaaa ttatgatgaa atgtatccag ttaatacagg taatccttat 268680 atcgttgcag gacaaagaaa agaagacaaa gctaaaccta aatatagatt aagattttta 268740 taagagaa 268748 <210> 2 <211> 798 <212> DNA <213> Endolysin LysPALS21 <400> 2 atgaaaacta aaactcaagc tttgaattgg gttaataatc gtattggtcg tagacttgac 60 atggatggag cttatggagc tcaatgtatg gatttgacta tcggttattg taattattta 120 actgatggaa aattctggcc ttggggtaac gctaaagatc ttaaaagtaa tacaatgcct 180 tcaggatgga aacttattaa aaatactcca tcattcttac ctcaaccagg agatatagct 240 atttgggcta atcctccata tgatgtttat ggtcatacag gtattatcac ttcagctaac 300 ttaaacaatt tctattcaat tgaccagaac tggtttaacg caggtagcaa tggttcacct 360 gcagctaaag tattccatga ttatacagga ttttggggag taattcgtcc agcctttagt 420 agtacagcta ctaaaaaagc aactactaag aaagcagctc ctaagaaaaa agtagttaag 480 aaagcagctc ctaagaaagc tgttacatct gctaaatgga aacgtaattc agcaggtatt 540 ctatggaaaa ctgaaaaagc tactttcaaa tgtaatgttg cttcaggaat tattactcgt 600 aaaaatggtc catggactgg atggcctaca ggtccattca tgaaaaaagg cgactctatt 660 aaatacgaag aaatccaaga ctttgatggt cttatctggg tttcaggtaa atttaaagga 720 caatatgtat acgtgccaat tggtaaatca aatggtaaag gacaacgtat tggtaacgca 780 tggggaacat ttagttaa 798 <210> 3 <211> 265 <212> PRT <213> Endolysin LysPALS21 <400> 3 Met Lys Thr Lys Thr Gln Ala Leu Asn Trp Val Asn Asn Arg Ile Gly 1 5 10 15 Arg Arg Leu Asp Met Asp Gly Ala Tyr Gly Ala Gln Cys Met Asp Leu 20 25 30 Thr Ile Gly Tyr Cys Asn Tyr Leu Thr Asp Gly Lys Phe Trp Pro Trp 35 40 45 Gly Asn Ala Lys Asp Leu Lys Ser Asn Thr Met Pro Ser Gly Trp Lys 50 55 60 Leu Ile Lys Asn Thr Pro Ser Phe Leu Pro Gln Pro Gly Asp Ile Ala 65 70 75 80 Ile Trp Ala Asn Pro Tyr Asp Val Tyr Gly His Thr Gly Ile Ile 85 90 95 Thr Ser Ala Asn Leu Asn Asn Phe Tyr Ser Ile Asp Gln Asn Trp Phe 100 105 110 Asn Ala Gly Ser Asn Gly Ser Pro Ala Ala Lys Val Phe His Asp Tyr 115 120 125 Thr Gly Phe Trp Gly Val Ile Arg Pro Ala Phe Ser Ser Thr Ala Thr 130 135 140 Lys Lys Ala Thr Thr Lys Lys Ala Ala Pro Lys Lys Lys Val Val Lys 145 150 155 160 Lys Ala Ala Pro Lys Lys Ala Val Thr Ser Ala Lys Trp Lys Arg Asn 165 170 175 Ser Ala Gly Ile Leu Trp Lys Thr Glu Lys Ala Thr Phe Lys Cys Asn 180 185 190 Val Ala Ser Gly Ile Ile Thr Arg Lys Asn Gly Pro Trp Thr Gly Trp 195 200 205 Pro Thr Gly Pro Phe Met Lys Lys Gly Asp Ser Ile Lys Tyr Glu Glu 210 215 220 Ile Gln Asp Phe Asp Gly Leu Ile Trp Val Ser Gly Lys Phe Lys Gly 225 230 235 240 Gln Tyr Val Tyr Val Pro Ile Gly Lys Ser Asn Gly Lys Gly Gln Arg 245 250 255 Ile Gly Asn Ala Trp Gly Thr Phe Ser 260 265 <210> 4 <211> 951 <212> DNA <213> Endolysin LysPALS22 <400> 4 atggctaaaa aacatatcgg tacatggaac ggtgttcctg tttatactga ttttttacca 60 ataggtactc gtagagctgg agataagctt aacggaccta aatttattgt tgctcatgac 120 acaggaaacc ctaacactac tgcccaaaat aatgttgatt actatcgtaa ttcatataat 180 attgattgga actatacagc atcagctcat atctttgttg atgataaaga atgtattatc 240 tgtgttcctt tagatgaaaa agcatggcat gttatgtaca atacacctac tgataattct 300 tggtatggta ttgatgctaa tgatggcgct attggtgttg aaggatgtta cttctctaat 360 agaagtcgtt cattaaaatc atttgataac tattgtcgtg ttcttgcttt cttatgtaaa 420 gaatataaaa ttaatgcaag tacaaatatg ccaggacatc aagatatcca agcagacaaa 480 caagatccag gcaatttatt agctgcatgc ggtatgtctc gtagtgtttc taatgtagat 540 aaaaaggttc taacttatat gaaaaatggt gctacttcta cagctaaaac ttcaacagca 600 actaaatcta ctactacaac taaagcacct gctaaaccta agaaaacaag tactgaaact 660 tcaactactt ggaaacgtaa ttcagcaggt attctatgga aaactgaaaa agctactttc 720 aaatgtggtg tatctgtagg aattattact cgtaaaaatg gtccatggac tggatggcct 780 caaggtcctc gtatgtctaa aggtgatact attaaatatg atgaaatcca agattttaac 840 ggatatattt gggtttcagg taaatttaag ggacaatatg tatacgtacc agtaggtaaa 900 tcaaatggta acggtaaacg tattggtcca gcatggggaa catttagcta a 951 <210> 5 <211> 316 <212> PRT <213> Endolysin LysPALS22 <400> 5 Met Ala Lys Lys His Ile Gly Thr Trp Asn Gly Val Pro Val Tyr Thr 1 5 10 15 Asp Phe Leu Pro Ile Gly Thr Arg Arg Ala Gly Asp Lys Leu Asn Gly 20 25 30 Pro Lys Phe Ile Val Ala His Asp Thr Gly Asn Pro Asn Thr Thr Ala 35 40 45 Gln Asn Asn Val Asp Tyr Tyr Arg Asn Ser Tyr Asn Ile Asp Trp Asn 50 55 60 Tyr Thr Ala Ser Ala His Ile Phe Val Asp Asp Lys Glu Cys Ile Ile 65 70 75 80 Cys Val Pro Leu Asp Glu Lys Ala Trp His Val Met Tyr Asn Thr Pro 85 90 95 Thr Asp Asn Ser Trp Tyr Gly Ile Asp Ala Asn Asp Gly Ala Ile Gly 100 105 110 Val Glu Gly Cys Tyr Phe Ser Asn Arg Ser Arg Ser Leu Lys Ser Phe 115 120 125 Asp Asn Tyr Cys Arg Val Leu Ala Phe Leu Cys Lys Glu Tyr Lys Ile 130 135 140 Asn Ala Ser Thr Asn Met Pro Gly His Gln Asp Ile Gln Ala Asp Lys 145 150 155 160 Gln Asp Pro Gly Asn Leu Leu Ala Ala Cys Gly Met Ser Arg Ser Val 165 170 175 Ser Asn Val Asp Lys Lys Val Leu Thr Tyr Met Lys Asn Gly Ala Thr 180 185 190 Ser Thr Ala Lys Thr Ser Thr Ala Thr Lys Ser Thr Thr Thr Thr Lys 195 200 205 Ala Pro Ala Lys Pro Lys Lys Thr Ser Thr Glu Thr Ser Thr Thr Trp 210 215 220 Lys Arg Asn Ser Ala Gly Ile Leu Trp Lys Thr Glu Lys Ala Thr Phe 225 230 235 240 Lys Cys Gly Val Ser Val Gly Ile Ile Thr Arg Lys Asn Gly Pro Trp 245 250 255 Thr Gly Trp Pro Gln Gly Pro Arg Met Ser Lys Gly Asp Thr Ile Lys 260 265 270 Tyr Asp Glu Ile Gln Asp Phe Asn Gly Tyr Ile Trp Val Ser Gly Lys 275 280 285 Phe Lys Gly Gln Tyr Val Tyr Val Pro Val Gly Lys Ser Asn Gly Asn 290 295 300 Gly Lys Arg Ile Gly Pro Ala Trp Gly Thr Phe Ser 305 310 315
Claims (4)
Endolysin LysPALS21 consisting of the amino acid sequence of SEQ ID NO: 3, characterized in that it has lytic activity against Staphylococcus aureus.
상기 황색포도상구균은,
메티실린 저항성 황색포도상구균(Methicillin-resistant S. aureus, MRSA) 또는 메티실린 감수성 황색포도상구균(Methicillin-sensitivity S. aureus, MSSA)인 것을 특징으로 하는 엔도라이신 LysPALS21.
According to claim 1,
The Staphylococcus aureus is
Methicillin-resistant Staphylococcus aureus (Methicillin-resistant S. aureus , MRSA) or methicillin-sensitive Staphylococcus aureus (Methicillin-sensitivity S. aureus , MSSA), characterized in that the endolysin LysPALS21.
Feed composition comprising the endolysin LysPALS21 consisting of the amino acid sequence of SEQ ID NO: 3.
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| KR1020210090965A KR102360880B1 (en) | 2020-05-20 | 2021-07-12 | Endolysins LysPALS21 of Jumbo bacteriophage PALS2 from Staphylococcus aureus |
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| KR1020200060418A KR102358905B1 (en) | 2020-05-20 | 2020-05-20 | Jumbo bacteriophage PALS2 and its endolysins LysPALS21 and LysPALS22 from Staphylococcus aureus |
| KR1020210090965A KR102360880B1 (en) | 2020-05-20 | 2021-07-12 | Endolysins LysPALS21 of Jumbo bacteriophage PALS2 from Staphylococcus aureus |
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| KR1020210090965A KR102360880B1 (en) | 2020-05-20 | 2021-07-12 | Endolysins LysPALS21 of Jumbo bacteriophage PALS2 from Staphylococcus aureus |
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| KR100914163B1 (en) * | 2007-08-16 | 2009-08-28 | 주식회사 인트론바이오테크놀로지 | Antimicrobial Protein Derived From Podoviridae Bacteriophage Specific To Staphylococcus aureus |
| KR101174809B1 (en) * | 2010-05-27 | 2012-08-20 | 경북대학교 산학협력단 | A bacteriophage killing Staphylococcus aureus |
| KR101596665B1 (en) | 2013-05-29 | 2016-02-23 | 서울대학교산학협력단 | Bacteriophage against Staphylococcus aureus and composition thereof |
| KR101796279B1 (en) * | 2016-01-21 | 2017-11-10 | 서울대학교 산학협력단 | Endolysin with novel host binding domain from Staphylococcus aureus bacteriophage SA11 and antibiotic composition thereof |
| KR102003770B1 (en) * | 2016-12-23 | 2019-07-25 | 주식회사 옵티팜 | Novel Staphylococcus specific bacteriophage SA3 and antibacterial composition comprising the same |
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