KR102355956B1 - 암호화된 태그리스 화학 라이브러리 - Google Patents

암호화된 태그리스 화학 라이브러리 Download PDF

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KR102355956B1
KR102355956B1 KR1020197016158A KR20197016158A KR102355956B1 KR 102355956 B1 KR102355956 B1 KR 102355956B1 KR 1020197016158 A KR1020197016158 A KR 1020197016158A KR 20197016158 A KR20197016158 A KR 20197016158A KR 102355956 B1 KR102355956 B1 KR 102355956B1
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KR20190072651A (ko
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데이빗 휴 윌리엄스
입쉬타 맨달
스튜어트 로버트 우드
대니얼 브라턴
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난나 테라퓨틱스 리미티드
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    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
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    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
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KR1020197016158A 2016-11-08 2017-11-08 암호화된 태그리스 화학 라이브러리 Expired - Fee Related KR102355956B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1618820.3 2016-11-08
GB201618820 2016-11-08
GB1709718.9 2017-06-19
GBGB1709718.9A GB201709718D0 (en) 2017-06-19 2017-06-19 Tagless encoded chemical library
PCT/GB2017/053360 WO2018087539A1 (en) 2016-11-08 2017-11-08 Tagless encoded chemical library

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KR20190072651A KR20190072651A (ko) 2019-06-25
KR102355956B1 true KR102355956B1 (ko) 2022-01-25

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US (2) US20190264199A1 (enExample)
EP (1) EP3538653B1 (enExample)
JP (2) JP2020503846A (enExample)
KR (1) KR102355956B1 (enExample)
CN (1) CN110249050B (enExample)
AU (1) AU2017357638B2 (enExample)
CA (1) CA3042974A1 (enExample)
IL (1) IL266318B2 (enExample)
WO (1) WO2018087539A1 (enExample)

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US11084037B2 (en) * 2017-09-25 2021-08-10 Plexium, Inc. Oligonucleotide encoded chemical libraries
CN110658163A (zh) * 2018-06-29 2020-01-07 成都先导药物开发股份有限公司 一种合成dna编码化合物中的反应监测方法
GB201817321D0 (en) * 2018-10-24 2018-12-05 Nanna Therapeutics Ltd Microbeads for tagless encoded chemical library screening
WO2020096015A1 (ja) * 2018-11-07 2020-05-14 国立大学法人 東京大学 １種以上の被検物質と共存した細胞のゲノム関連情報を検出する方法
WO2020206114A1 (en) * 2019-04-02 2020-10-08 The Trustees Of Columbia University In The City Of New York Sequencing by synthesis with energy transfer dye pairs
EP3956467A1 (en) 2019-04-16 2022-02-23 F. Hoffmann-La Roche AG Small molecule screening cellular assay using modified beads
CN112143783B (zh) * 2019-06-27 2024-09-24 成都先导药物开发股份有限公司 一种可识别混合物对复杂生物体系的鉴别方法
CN114829626A (zh) 2019-10-10 2022-07-29 1859公司 用于微流体筛选的方法和系统
CN114761577B (zh) * 2020-01-10 2025-10-24 新克赛特株式会社 新型细胞表型筛选方法
CN111304753B (zh) * 2020-03-24 2020-12-01 深圳奇点药物科技有限公司 Dna编码分子库的筛选方法和试剂盒
US11628382B2 (en) 2020-08-26 2023-04-18 Duke University Methods and apparatuses for purification of gel droplets supporting biological tissue
US20230357757A1 (en) * 2020-10-23 2023-11-09 Eth Zurich Self-purified nucleic acid encoded libraries
CA3209941A1 (en) * 2021-03-04 2022-09-09 Corey M. DAMBACHER Molecular barcodes and related methods and systems
WO2023174845A1 (en) * 2022-03-13 2023-09-21 Eleven Therapeutics Ltd System and method for high throughput evaluation of chemical modifications of nucleic acid molecules

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WO2004087308A1 (en) 2003-03-31 2004-10-14 Medical Research Council Method of synthesis and testing of combinatorial libraries using microcapsules
JP2007527421A (ja) 2004-02-23 2007-09-27 ジェネンテック・インコーポレーテッド 複素環式自壊的リンカーおよび結合体

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EP2021113A2 (en) * 2006-05-11 2009-02-11 Raindance Technologies, Inc. Microfluidic devices
WO2010094036A1 (en) * 2009-02-13 2010-08-19 X-Chem, Inc. Methods of creating and screening dna-encoded libraries
WO2012019765A1 (en) * 2010-08-10 2012-02-16 European Molecular Biology Laboratory (Embl) Methods and systems for tracking samples and sample combinations
PL3650458T3 (pl) * 2015-02-24 2023-11-06 City Of Hope Platformy do analiz przesiewowych bibliotek kodowanych chemicznie i adresowanych przestrzennie
EP3268462B1 (en) * 2015-03-11 2021-08-11 The Broad Institute, Inc. Genotype and phenotype coupling

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
WO2004087308A1 (en) 2003-03-31 2004-10-14 Medical Research Council Method of synthesis and testing of combinatorial libraries using microcapsules
JP2006521922A (ja) 2003-03-31 2006-09-28 メディカル リサーチ カウンシル マイクロカプセルを用いたコンビナトリアルライブラリの合成および試験の方法
JP2007527421A (ja) 2004-02-23 2007-09-27 ジェネンテック・インコーポレーテッド 複素環式自壊的リンカーおよび結合体

Non-Patent Citations (1)

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Title
비특허문헌 1

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IL266318B2 (en) 2023-10-01
IL266318B1 (en) 2023-06-01
CA3042974A1 (en) 2018-05-17
AU2017357638A1 (en) 2019-05-16
IL266318A (en) 2019-06-30
CN110249050B (zh) 2023-08-18
JP2020503846A (ja) 2020-02-06
EP3538653A1 (en) 2019-09-18
KR20190072651A (ko) 2019-06-25
JP2022180348A (ja) 2022-12-06
US20190264199A1 (en) 2019-08-29
US20220073907A1 (en) 2022-03-10
WO2018087539A1 (en) 2018-05-17
EP3538653B1 (en) 2021-07-28
AU2017357638B2 (en) 2023-11-16
CN110249050A (zh) 2019-09-17

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