KR102289190B9 - 9-cis Beta-carotene의 합성방법 - Google Patents

9-cis Beta-carotene의 합성방법

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Publication number
KR102289190B9
KR102289190B9 KR1020190137160A KR20190137160A KR102289190B9 KR 102289190 B9 KR102289190 B9 KR 102289190B9 KR 1020190137160 A KR1020190137160 A KR 1020190137160A KR 20190137160 A KR20190137160 A KR 20190137160A KR 102289190 B9 KR102289190 B9 KR 102289190B9
Authority
KR
South Korea
Prior art keywords
carotene
cis beta
synthesis method
cis
beta
Prior art date
Application number
KR1020190137160A
Other languages
English (en)
Other versions
KR102289190B1 (ko
KR20210051646A (ko
Inventor
신병철
한보람
노현정
Original Assignee
(주)아크에이르
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by (주)아크에이르 filed Critical (주)아크에이르
Priority to KR1020190137160A priority Critical patent/KR102289190B1/ko
Publication of KR20210051646A publication Critical patent/KR20210051646A/ko
Application granted granted Critical
Publication of KR102289190B1 publication Critical patent/KR102289190B1/ko
Publication of KR102289190B9 publication Critical patent/KR102289190B9/ko

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/225Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5442Aromatic phosphonium compounds (P-C aromatic linkage)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020190137160A 2019-10-31 2019-10-31 9-cis Beta-carotene의 합성방법 KR102289190B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020190137160A KR102289190B1 (ko) 2019-10-31 2019-10-31 9-cis Beta-carotene의 합성방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020190137160A KR102289190B1 (ko) 2019-10-31 2019-10-31 9-cis Beta-carotene의 합성방법

Publications (3)

Publication Number Publication Date
KR20210051646A KR20210051646A (ko) 2021-05-10
KR102289190B1 KR102289190B1 (ko) 2021-08-12
KR102289190B9 true KR102289190B9 (ko) 2022-01-17

Family

ID=75917597

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020190137160A KR102289190B1 (ko) 2019-10-31 2019-10-31 9-cis Beta-carotene의 합성방법

Country Status (1)

Country Link
KR (1) KR102289190B1 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102385617B1 (ko) 2021-11-01 2022-04-14 (주)아크에이르 신규 화합물 Potassium all-trans retinoate(PARA) 및 Potassium 9-cis retinoate(P9-cis RA) 를 포함하는 종양 세포 사멸 및 전이 억제용 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100477899B1 (ko) 2001-04-12 2005-03-18 구상호 레티놀 및 카로틴 화합물의 실용적인 합성방법
KR102016078B1 (ko) 2012-11-30 2019-08-30 (주)아모레퍼시픽 심장 질환 예방 또는 치료용 조성물
WO2016076454A1 (ko) 2014-11-10 2016-05-19 한국생명공학연구원 미생물의 배양방법 및 그 배양미생물로부터 9-시스 베타카로틴의 분리 및 정제방법
IL245847A0 (en) * 2016-05-25 2016-08-02 Ramot At Tel-Aviv Univ Ltd A method for the synthesis of 9-cis-beta-carotene and preparations including it

Also Published As

Publication number Publication date
KR102289190B1 (ko) 2021-08-12
KR20210051646A (ko) 2021-05-10

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E701 Decision to grant or registration of patent right
G170 Publication of correction