KR102265020B1 - Cosmetic composition using schisandra chinensis extract containing high concentration of lignan - Google Patents

Abstract

According to an embodiment of the present disclosure, disclosed is a method for extracting an extract of Schisandra chinensis including an effective lignan with skin whitening and anti-wrinkle effects. The method includes the steps of obtaining a primary extract by ultrasonically extracting Schisandra chinensis with an extraction solvent; and filtering the primary extract and distilling the same under reduced pressure to obtain an extract of Schisandra chinensis.

Description

Cosmetic composition using Schisandra extract containing high concentration lignan {COSMETIC COMPOSITION USING SCHISANDRA CHINENSIS EXTRACT CONTAINING HIGH CONCENTRATION OF LIGNAN}

The present disclosure relates to a method for extracting a Schisandra extract and a cosmetic composition using the same, and more particularly, to a method for extracting a Schisandra extract containing a high concentration of some lignan components and a cosmetic composition using the same.

Schisandra chinensis (Schisandra chinensis) is a deciduous deciduous tree of the Schisandra family, a well-known medicinal plant in oriental medicine, and a material used in various foods and beverages. In particular, 40 from Schisandra including gomisin A, B, C, D, E, F, G, K3, N, J, schisandrol B, schisandrin A and sisandrine C As various lignan components are known, studies on Schisandra are being actively conducted.

In particular, lignans contained in the flesh, peel, or seeds of Schisandra fruit are known to have beneficial effects on skin health, such as antioxidant, anti-inflammatory and whitening effects.

Accordingly, there is a need in the art for a method of extracting a Schisandra extract containing lignan components contained in Schisandra at a high concentration and a cosmetic composition using the Schisandra extract.

Korean Registered Patent No. 10-1807548

The present disclosure is to improve the problems of the prior art, and to provide a Schisandra extract containing some lignan components at a high concentration and a cosmetic composition using the same.

The technical problems of the present disclosure are not limited to the technical problems mentioned above, and other technical problems not mentioned will be clearly understood by those skilled in the art from the following description.

According to an embodiment of the present disclosure for realizing the above-described problem, there is provided a method for extracting a Schisandra extract containing an effective lignan, the method comprising: ultrasonically extracting a Schisandra material with an extraction solvent to obtain a primary extract; and filtering the primary extract and distilling under reduced pressure to obtain the Schisandra extract.

Alternatively, the extraction solvent is 70% or more and 99% or less ethanol, the Schisandra material includes at least one of Schisandra seeds or Schisandra fruit, and the weight ratio of the ethanol and the Schisandra material is 10:1 can be

Alternatively, the effective lignan is a group of lignan components comprising Gomisin A, Schisandrin A, and Gomisin N, and the concentration of Gomisin A is the Schisandra extract 10,000ppm or more and 40,000ppm or less, the concentration of sijandrine A is 10,000ppm or more and 20,000ppm or less for the Schisandra extract, and the concentration of Gomisin N is 40,000ppm or more and 60,000ppm or less for the Schisandra extract. have.

According to another embodiment of the present disclosure for realizing the above-described problems, a cosmetic composition composed of micro-nano capsules is disclosed. The cosmetic composition comprises: an oil part comprising a Schisandra extract and an oil for dilution; Water part (water part) comprising purified water and polyol (polyol); and a surfactant, and the Schisandra extract may contain effective lignans.

Alternatively, the cosmetic composition may include 0.1 to 3 parts by weight of the Schisandra extract; 5 to 20 parts by weight of the paid part; 2 to 8 parts by weight of the surfactant; 10 to 20 parts by weight of the purified water; and 40 to 60 parts by weight of the polyol.

Alternatively, 0.1 to 2 parts by weight of an additive for preventing oxidation or spoilage of the cosmetic composition may be further included.

Alternatively, the effective lignan is 1,000 ppm or more and 1,500 ppm or less with respect to the Schisandra extract, and the concentration of gomisin A contained in the effective lignan is 200 ppm or more and 300 ppm or less with respect to the Schisandra extract, and the effective lignan contains The concentration of sijandrine A may be 150 ppm or more and 200 ppm or less with respect to the Schisandra extract, and the concentration of gomisin N contained in the effective lignan may be 800 ppm or more and 900 ppm or less with respect to the Schisandra extract.

Alternatively, the micro-nano capsules may have a size of 150 nm or more and 100 μm or less, and may have a micelle structure in which the surfactant surrounds the oil phase part.

According to another embodiment of the present disclosure for realizing the above-described problems, a method for preparing a cosmetic composition composed of micro-nano capsules is disclosed. The method comprises the steps of preparing an oily part by diluting the Schisandra extract in oil for dilution; forming a mixture comprising the oil phase part, the aqueous phase part and a surfactant; forming the micro-nanocapsules of the micelle structure by using the mixture with a homo mixer; and applying pressure to the mixture using a high-pressure homogenizer to adjust the size of the micro-nano capsules, and the Schisandra extract may include effective lignans.

Alternatively, the step of applying pressure to the mixture using a high pressure homogenizer to adjust the size of the micro-nano capsules uses a high pressure homogenizer to adjust the size of the micro-nano capsules to a size of 150 nm or more and 100 μm or less. and applying a pressure of 1,000 bar or more to 1,500 bar or less to the mixture.

The technical solutions obtainable in the present disclosure are not limited to the above-mentioned solutions, and other solutions that are not mentioned are clearly to those of ordinary skill in the art to which the present disclosure belongs from the description below. can be understood

The extraction method according to the embodiments of the present disclosure may provide a Schisandra extract containing active lignan ingredients effective in skin whitening and wrinkle improvement at a high concentration.

In addition, it is possible to provide a method for preparing a cosmetic composition with high stability of the Schisandra extract.

Effects obtainable in the present disclosure are not limited to the above-mentioned effects, and other effects not mentioned will be clearly understood by those of ordinary skill in the art to which the present disclosure belongs from the description below. .

1A is a graph showing the effective lignan content of Schisandra extract extracted with ethanol of 70% purity according to an embodiment of the present disclosure.
1B is a graph showing the effective lignan content of Schisandra extract extracted with ethanol of 99% purity according to an embodiment of the present disclosure.
Figure 2a is a graph showing the change in the content of gomisin N by exposing Example 2 and Comparative Example 4 to different temperature environments.
Figure 2b is a graph showing the change in the content of gomisin A by exposing Example 2 and Comparative Example 4 to different temperature environments.
Figure 2c is a graph showing the change in the content of sijandrin A by exposing Example 2 and Comparative Example 4 to different temperature environments.

Various embodiments are now described with reference to the drawings. In this specification, various descriptions are presented to provide an understanding of the present disclosure. However, it is apparent that these embodiments may be practiced without these specific descriptions.

In addition, the term “or” is intended to mean an inclusive “or” rather than an exclusive “or.” That is, unless otherwise specified or clear from context, "X employs A or B" is intended to mean one of the natural implicit substitutions. That is, X employs A; X employs B; or when X employs both A and B, "X employs A or B" may apply to either of these cases. It should also be understood that the term “and/or” as used herein refers to and includes all possible combinations of one or more of the listed related items.

Also, the terms "comprises" and/or "comprising" should be understood to mean that the feature and/or element in question is present. However, it should be understood that the terms "comprises" and/or "comprising" do not exclude the presence or addition of one or more other features, elements and/or groups thereof. Also, unless otherwise specified or unless the context is clear as to designating a singular form, the singular in the specification and claims should generally be construed to mean "one or more."

The effective lignan of the present disclosure refers to a group of lignan components consisting of gomisin A (Gomisin A), sisandrin A (Schisandrin A) and gomisin N (Gomisin N) among the lignan components included in Schisandra. That is, the effective lignan of the present disclosure means a group of some lignan components among the lignan components included in Schisandra, wherein some lignan components refer to gomisin A, sijandrine A, and gomisin N.

According to an embodiment of the present disclosure, the extract refers to a preparation obtained by squeezing a crude drug with an appropriate leaching solution and concentrated, and may be an extract, a diluent, a concentrate, or a dried product obtained by drying the extract obtained by extraction treatment or a purified product thereof.

The Schisandra material of the present disclosure may be a raw material, and may include at least one of Schisandra seeds or Schisandra fruit. That is, the Schisandra extract extracted according to an embodiment of the present disclosure may be an extract extracted from Schisandra seeds, Schisandra fruit, or a combination thereof.

The extraction solvent of the present disclosure is a solvent used to extract the extract from the raw material, and may be ethanol having a purity of 70% or more and 99% or less.

Hereinafter, a method for extracting a Schisandra extract containing effective lignans from Schisandra material according to a preferred embodiment of the present disclosure will be described.

Example 1 and Comparative Examples 1-3. Preparation of Schisandra extract

According to a preferred embodiment of the present disclosure, crushed Schisandra seeds and 99% pure ethanol (EtOH) are weighed at a weight ratio of 1:10, and ultrasonic extraction is performed at 60° C. for 60 minutes with a sonicator to obtain a primary extract After filtering the remaining Schisandra material through a paper filter, the resulting primary extract was distilled under reduced pressure at 60° C. to extract the Schisandra extract to prepare Example 1.

Comparative Example 1 was prepared by substituting Schisandra seeds for Schisandra fruit in the method for preparing Example 1 described above and extracting Schisandra extract under the same process conditions.

In addition, in the method of preparing Example 1 described above, 99% purity ethanol was replaced with 70% purity ethanol, and the Schisandra extract was extracted under the same process conditions to prepare Comparative Example 2.

In addition, Comparative Example 3 was prepared by substituting Schisandra seeds for Schisandra fruit in the method for preparing Comparative Example 2 described above and extracting the Schisandra extract under the same process conditions.

That is, Examples 1 and Comparative Examples 1 to 3 are Schisandra extracts extracted using different Schisandra material and ethanol of different purity, and are summarized in Table 1.

Example 1 Comparative Example 1 Comparative Example 2 Comparative Example 3 Schisandra material Mr. Omija Schisandra fruit Mr. Omija Schisandra fruit Purity of Ethanol 99% 99% 70% 70%

Table 1 above compares the purity of different Schisandra material and ethanol in the methods of preparing Example 1 and Comparative Examples 1 to 3.

Experimental Example 1. Evaluation of concentration of Schisandra extract

Concentrations of effective lignans contained in Example 1 and Comparative Examples 1 to 3 extracted according to an embodiment of the present disclosure were measured, and the results are shown in FIGS. 1A to 1B .

Specifically, FIG. 1A is a graph showing the effective lignan concentration for each of Example 1 and Comparative Example 1 extracted with 99% ethanol according to an embodiment of the present disclosure. 1B is a graph showing the effective lignan concentration for each of Comparative Examples 2 and 3 extracted with 70% ethanol according to an embodiment of the present disclosure. In addition, the concentration shown in FIGS. 1A to 1B is a concentration having a ppm unit.

1A to 1B , it can be seen that Examples 1 and Comparative Examples 1 to 3 include all of the effective lignans defined in the present disclosure.

In addition, it can be seen that each of the effective lignans of Example 1, gomisin A, sijandrine A, and gomisin N, was contained at a higher concentration than in Comparative Examples 1 and 3. In particular, it can be seen that the concentration of gomisin N of Example 1 has the highest concentration compared to Comparative Examples 1 to 3. In addition, it can be seen that each concentration of gomisin A and sijandrine A of Comparative Example 2 has the highest concentration compared to Comparative Examples 1 to 2 and Example 1.

Therefore, it can be seen that Examples 1 and 2 extracted from Schisandra seeds contained effective lignans at a higher concentration than Comparative Examples 1 and 3 extracted from Schisandra fruit.

Therefore, according to an embodiment of the present disclosure, when the Schisandra material including at least one of Schisandra seeds or Schisandra fruit is extracted with ethanol as an extraction solvent, a Schisandra extract containing the effective lignan of the present disclosure may be prepared. In addition, the higher the ratio of Schisandra seeds contained in the Schisandra material, the higher the Schisandra extract containing effective lignans at a high concentration can be prepared.

Here, the specific range of the high concentration effective lignan may be determined based on Example 1 and Comparative Example 2 having the highest effective lignan concentration through Experimental Example 1.

Specifically, the concentration of gomisin A among the effective lignans contained in the Schisandra extract extracted according to a preferred embodiment of the present disclosure is 10,000 ppm or more and 40,000 ppm or less with respect to the Schisandra extract, and the concentration of sijandrine A is 10,000 ppm or more and 20,000 ppm or less, and the concentration of gomisin N may be 40,000 ppm or more and 60,000 ppm or less with respect to the Schisandra extract.

More preferably, the concentration of gomisin A is 15,000 ppm or more and 35,000 ppm or less with respect to the Schisandra extract, the concentration of sijandrine A is 10,000 ppm or more and 15,000 ppm or less with respect to the Schisandra extract, and the concentration of gomisin N is the Schisandra extract It may be 42,000 ppm or more and 55,000 ppm or less.

Hereinafter, a cosmetic composition and a method for preparing the cosmetic composition including the Schisandra extract prepared according to an embodiment of the present disclosure will be described.

The cosmetic composition according to another embodiment of the present disclosure may include an oily part including the Schisandra extract and the oil for dilution. Specifically, the cosmetic composition may contain 5 to 20 parts by weight of the oily part.

Here, the Schisandra extract is an Schisandra extract extracted according to an embodiment of the present disclosure, and is an extract containing an effective lignan composed of gomisin A, sijandrine A, and gomisin N.

The diluting oil of the present disclosure may include at least one of Caprylic/Capric Triglyceride (MCT oil), Octyldodecanol (Eutanol G), Dimethicone, Sweet amond oil, Castor oil, Olive oil, Squalane, Macadamia nut oil, or Sunflower oil. have.

Specifically, in the cosmetic composition according to another embodiment of the present disclosure, the effective lignan concentration of the Schisandra extract diluted with the oil for dilution is preferably 1,000 ppm or more and 1,500 ppm or less.

More specifically, the concentration of Gomisin A contained in the effective lignan of the Schisandra extract diluted with the oil for dilution is 200 ppm or more and 300 ppm or less with respect to the Schisandra extract, and the concentration of Sijandrine A is 150 ppm or more and 200 ppm or less with respect to the Schisandra extract. And, the concentration of gomisin N is preferably 800ppm or more and 900ppm or less with respect to the Schisandra extract.

Based on the above-described preferred concentration range of the effective lignan, the cosmetic composition may contain 0.1 to 3 parts by weight of Schisandra extract.

The cosmetic composition according to another embodiment of the present disclosure may include a water phase part including purified water and a polyol. Specifically, the cosmetic composition preferably contains 10 to 20 parts by weight of purified water and 40 to 60 parts by weight of a polyol.

The polyol of the present disclosure may include at least one of Glycerin, 1,3-Butyleneglycol, 1,3-Propanediol, Methylpropanediol, Propylene glycol, Dipropylene glycol, and Penthylene glycol.

In addition, the cosmetic composition according to another embodiment of the present disclosure may include a surfactant. Specifically, the cosmetic composition preferably contains 2 to 8 parts by weight of a surfactant.

The surfactant of the present disclosure may be an emulsifier, and may include one or more of Lecithin, Polyglyceryl-3 Methylglucose Distearate, Polyglyceryl-4 Caprate, Cetostearyl alcohol, Stearic acid, Lauric acid, or Palmitic acid.

An additive for preventing oxidation or spoilage of the cosmetic composition of the present disclosure may be additionally added.

The additive of the present disclosure may include at least one of Tocopherol E acetate, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, BHT, Ethylhexylglycerin, 1,2-Hexanediol, Phenoxyethanol, and Sodium benzoate.

The cosmetic composition according to another embodiment of the present disclosure may be prepared to consist of micro-nano capsules in order to increase the stability and preservation of the Schisandra extract prepared according to an embodiment of the present disclosure.

Specifically, the cosmetic composition according to another embodiment of the present disclosure may be an O/W (Oil in Water) type composition. The micro-nano capsules included in the cosmetic composition of the present disclosure may have a size of 150 nm or more and 100 μm or less, and may be capsules having a micelle structure in which the surfactant surrounds the oil phase part.

Hereinafter, a method for preparing a cosmetic composition composed of micro-nano capsules according to another embodiment of the present disclosure described above will be described.

Example 2. Preparation of a cosmetic composition

The cosmetic composition of Example 2 comprising the Schisandra extract of Example 1 prepared according to an embodiment of the present disclosure was prepared according to the following steps.

1) The oily part was prepared by diluting the Schisandra extract of Example 1 with Caprylic/Capric Triglyceride so that the effective lignan concentration was 1000ppm based on the Schisandra extract.

2) 13 parts by weight of the oil phase part and 60 parts by weight of Glycerin were weighed and heated and stirred at 60 to 70° C. to produce a mixture.

3) When the temperature of the mixture reached 60°C, 3 parts by weight of Tegocare 450 and 1 part by weight of Emulmetik 100 as emulsifiers were added to complete dissolution.

4) After complete dissolution, 0.5 parts by weight of an additive, an antioxidant, Tocopherol E acetate was added and stirred continuously for 5 minutes to obtain a composition prepared in Comparative Example 4.

5) The composition prepared in the previous step 4) was emulsified at 3,000 rpm for 5 minutes using a homo mixer to prepare micro-sized micellar-structured capsules.

6) Using a high pressure homogenizer (HPH) to adjust the size of at least some of the micro-sized capsules to nano-sized capsules, the composition prepared in the previous step 5) of 1,000 to 1,500 bar Example 2 was prepared by applying pressure three times.

The components and content ratios of Example 2 prepared as described above are shown in Table 2 below.

ingredient Content ratio (parts by weight) paid part 13 Glycerin (polyol) 60 Purified water 22.5 Tegocare450 (emulsifier) 3 Emulmetik 100 (emulsifier) One Tocopherol E acetate (additive 0.5

Glycerin described in the preparation steps described above and in Table 2 was used as the polyol. In addition, Tegocare450 is a material product of Polyglyceryl-3 Methylglucose Distearate and was used as an emulsifier. In addition, Emulmetik 100 is a material product of Lecithin and was used as an emulsifier. In addition, Caprylic/Capric Triglyceride, which is a component included in the oil phase in the above-mentioned manufacturing steps, was used as an oil for dilution.

Among the steps 1) to 6) described above, steps 5) and 6) can be viewed as encapsulation steps. The micro-nano capsules formed in the encapsulation steps may have a size of 150 nm or more and 100 μm or less, and may have a micelle structure in which the surfactant surrounds the oil phase part. That is, the micro-nano capsules have a micelle structure and may contain the Schisandra extract as in Example 1 of the present disclosure therein.

After that, the composition obtained in step 4), which is a non-encapsulated composition, was used as Comparative Example 4, and Experimental Example 2 was conducted to evaluate the stability according to whether encapsulation was performed.

Experimental Example 2. Stability evaluation of effective lignans

In order to evaluate the stability of the cosmetic composition of Example 2 composed of micro-nano capsules, Experimental Example 2 was conducted in which Example 2 and Comparative Example 4 were exposed to different temperature environments for a long period of time. Here, the stability of the cosmetic composition is the stability of the effective lignan included in the cosmetic composition, and specifically, it may be related to the rate at which the content ratio of the effective lignan included in the cosmetic composition decreases with time. That is, high stability means that the rate at which the content ratio of the effective lignan contained in the cosmetic composition decreases over time is slow.

Specifically, Experimental Example 2 exposes each of the cosmetic composition of Example 2 and the composition of Comparative Example 4 to 25 ℃, 45 ℃ and Sun (sunlight) environment, and in each of Examples 2 and 4 at 2 week intervals. It is an experiment conducted for 6 weeks to measure the content change of each of the included gomisin A, gomisin N, and sijandrine A.

The content changes of each gomisin A, gomisin N, and sijandrine A measured according to Experimental Example 2 are shown in the graphs shown in FIGS. 2a to 2c.

Figure 2a is a graph showing the change in the content of gomisin N by exposing Example 2 and Comparative Example 4 to different temperature environments. Figure 2b is a graph showing the change in the content of gomisin A by exposing Example 2 and Comparative Example 4 to different temperature environments. Figure 2c is a graph showing the change in the content of sijandrin A by exposing Example 2 and Comparative Example 4 to different temperature environments. Here, the different temperature environment means 25°C, 45°C and Sun environment.

Specifically, in the graphs shown in FIGS. 2A to 2C , the X-axis (horizontal axis) represents the experiment time, and numbers 0 to 6 on the X-axis mean 0 to 6 weeks. Week 0 means the time at which the experiment was started.

In addition, the Y-axis (vertical axis) in the graphs shown in FIGS. 2a to 2c represents the content ratio (%) of each gomisin A, gomisin N, and sijandrine A. At the time of starting the experiment, each content of gomisin A, gomisin N, and sijandrine A is set as a standard, and the content ratio is expressed as a percentage for 6 weeks at an interval of 2 weeks thereafter. Accordingly, at week 0 when the experiment was started, each content ratio of gomisin A, gomisin N, and sijandrine A was 100%.

Figure 2a shows the content ratio of gomisin N contained in each of Example 2 and Comparative Example 4 exposed to 25 ℃, 45 ℃ and Sun (sunlight) environment. As shown in Figure 2a, the content ratio of gomisin N contained in Example 2 does not change significantly during the experiment period of 6 weeks in 25 ℃, 45 ℃ and Sun (sunlight) environment, while Comparative Example 4 is 2 It shows a decreasing trend at weekly intervals. That is, it can be seen that the rate of decrease of the high misin N content in Comparative Example 4 is faster than that of Example 2 in 25 ° C., 45 ° C. and Sun (sunlight) environment.

Therefore, it can be seen that Example 2 composed of micro-nano capsules has higher stability of Gomisin N in 25 ℃, 45 ℃ and Sun (sunlight) environment than Comparative Example 4 which is not composed of capsules.

Figure 2b shows the content ratio of gomisin A contained in each of Example 2 and Comparative Example 4 exposed to 25 ℃, 45 ℃ and Sun (sunlight) environment. As shown in Figure 2b, it can be seen that the content ratio of gomisin A included in Example 2 does not change significantly during the experimental period of 6 weeks at 45 ℃ and Sun (sunlight) environment compared to Comparative Example 4. In particular, it can be seen that Comparative Example 4 decreases the content of gomisin A faster than Example 2 in a sunlight environment.

Therefore, it can be seen that Example 2 composed of micro-nano capsules has higher stability of Gomisin A in a high temperature environment, that is, 45° C. and Sun (sunlight) environment, than Comparative Example 4 which is not composed of capsules.

Figure 2c shows the content ratio of sijandrin A contained in each of Example 2 and Comparative Example 4 exposed to 25 ℃, 45 ℃ and Sun (sunlight) environment. As shown in Figure 2c, the content ratio of sijandrine A included in Example 2 did not change significantly during the 6 weeks of the experiment in 25 ℃, 45 ℃ and Sun (sunlight) environment, whereas Comparative Example 4 decreased shows a tendency to That is, it can be seen that the rate of decrease in the content of sijandrine A in Comparative Example 4 is faster than in Example 2 in 25 ℃, 45 ℃ and Sun (sunlight) environment.

Therefore, it can be seen that Example 2 composed of micro-nano capsules has higher stability of sijandrine A in 25 ° C, 45 ° C and Sun (sunlight) environment than Comparative Example 4 which is not composed of capsules.

According to Experimental Example 2 described above, the cosmetic composition comprising the Schisandra extract according to an embodiment of the present disclosure is composed of micro-nano capsules as in Example 2, so that even when exposed to various temperature environments for a long period of time, effective lignan content can be maintained.

The cosmetic composition according to the above-described embodiments of the present disclosure is a cosmetic of a formulation for application to the surface of the skin, and may include the cosmetic composition and other compoundable ingredients described below.

The cosmetic composition of the present disclosure may be prepared in a specific formulation by a method well known in the cosmetic field, and may further include an additive that is allowed to increase usefulness such as stability and quality of cosmetics. Such additives may include stabilizers, solubilizers, emulsifiers, vitamins, pigments, ingredients, carriers, chelating agents, antioxidants, bactericides, stabilizers, or combinations thereof, etc., depending on the type of formulation to be manufactured. may vary depending on

The cosmetic composition according to the embodiments of the present disclosure may be prepared in any formulation conventionally prepared in the art. For any formulation, e.g., solution, suspension, emulsion, paste, gel, cream, lotion, shampoo, surfactant-containing cleansing, emollient lotion, nourishing lotion, nourishing emulsion, nourishing cream, massage cream, essence, eye It may be a cream, a cleansing cream, a cleansing foam, a cleansing water, a pack, and the like.

As other ingredients that can be blended into the cosmetic composition according to embodiments of the present disclosure, oils and fats, emollients, organic and inorganic pigments, organic powders, UV absorbers, pH adjusters, alcohols, pigments, fragrances, blood circulation promoters, cooling agents, limiting agents etc. may exist.

The cosmetic composition of the present disclosure may be applied by applying an appropriate amount according to the skin part and area to be applied, and may be used repeatedly once to several times a day as needed. In addition, the amount and the number of times to be applied may be increased or decreased as needed according to the skin condition, age, etc.

The cosmetic composition of the present disclosure may be a composition including two or more essential components for a main effect among the components included in the cosmetic composition. The main effect is an effect that appears after the cosmetic composition is applied to the skin, and may be a whitening effect and wrinkle improvement effect, but the present disclosure is not limited thereto.

Descriptions of the presented embodiments are provided to enable those skilled in the art to use or practice the present disclosure. Various modifications to these embodiments will be apparent to those skilled in the art of the present disclosure. The generic principles defined herein may be applied to other embodiments without departing from the scope of the present disclosure. Therefore, the present disclosure is not limited to the embodiments presented herein. This disclosure is to be interpreted in the widest scope consistent with the principles and novel features presented herein.

Claims (10)

A method of extracting a Schisandra extract containing effective lignans, the method comprising:
Composing the weight ratio of Schisandra seeds and 70% or more and 99% or less of ethanol to 1:10, ultrasonically extracting the Schisandra seeds with the ethanol to obtain a primary extract; and
Filtering the primary extract and distilling under reduced pressure to obtain the Schisandra extract;
including, and
The effective lignan is
A group of lignan components consisting of Gomisin A, Schisandrin A and Gomisin N
Method for extracting Schisandra extract containing effective lignans
delete The method of claim 1,
The concentration of gomisin A is 10,000 ppm or more and 40,000 ppm or less with respect to the Schisandra extract,
The concentration of sijandrine A is 10,000 ppm or more and 20,000 ppm or less with respect to the Schisandra extract, and
The concentration of gomisin N is 40,000 ppm or more and 60,000 ppm or less with respect to the Schisandra extract,
A method for extracting Schisandra extract containing effective lignans.
A cosmetic composition composed of micro-nano capsules, the cosmetic composition comprising:
Oil part containing Schisandra extract and oil for dilution;
Water part (water part) comprising purified water and polyol (polyol); and
Surfactants;
including, and
The Schisandra extract is
It is obtained by filtering and distilling under reduced pressure the primary extract extracted by ultrasonication by composing the weight ratio of Schisandra seeds and ethanol of 70% or more and 99% or less to 1:10, and
comprising an effective lignan, a group of lignan components consisting of gomisin A, sizadrin A and gomisin N,
A cosmetic composition composed of micro-nano capsules.
5. The method of claim 4,
The cosmetic composition comprises:
0.1 to 3 parts by weight of the Schisandra extract;
5 to 20 parts by weight of the paid part;
2 to 8 parts by weight of the surfactant;
10 to 20 parts by weight of the purified water; and
40 to 60 parts by weight of the polyol;
containing,
A cosmetic composition composed of micro-nano capsules.
delete 5. The method of claim 4,
The effective lignan is 1,000 ppm or more and 1,500 ppm or less with respect to the Schisandra extract,
The concentration of gomisin A contained in the effective lignan is 200 ppm or more and 300 ppm or less with respect to the Schisandra extract,
The concentration of sijandrine A contained in the effective lignan is 150 ppm or more and 200 ppm or less with respect to the Schisandra extract, and
The concentration of gomisin N contained in the effective lignan is 800 ppm or more and 900 ppm or less with respect to the Schisandra extract,
A cosmetic composition composed of micro-nano capsules.
8. The method of claim 4, 5 or 7,
The micro-nano capsules are
It has a size of 150nm or more and 100um or less, and is a micelle structure in which the surfactant surrounds the oil phase part,
A cosmetic composition composed of micro-nano capsules.
In the method of manufacturing a cosmetic composition composed of micro-nano capsules, the method comprises:
diluting the Schisandra extract in oil for dilution to prepare oily parts;
forming a mixture comprising the oil phase part, the aqueous phase part and a surfactant;
forming the micro-nanocapsules of the micelle structure by using the mixture with a homo mixer; and
applying pressure to the mixture using a high pressure homogenizer (HPH) to adjust the size of the micro-nano capsules;
including, and
The Schisandra extract is
It is obtained by filtering and distilling under reduced pressure the primary extract extracted by ultrasonication by composing the weight ratio of Schisandra seeds and ethanol of 70% or more and 99% or less to 1:10, and
comprising an effective lignan, a group of lignan components consisting of gomisin A, sizadrin A and gomisin N,
A method for preparing a cosmetic composition composed of micro-nano capsules.
10. The method of claim 9,
The step of applying pressure to the mixture using a high-pressure homogenizer to adjust the size of the micro-nano capsules,
applying a pressure of 1,000 bar or more to 1,500 bar or less to the mixture using a high pressure homogenizer to adjust the size of the micro-nano capsules to a size of 150 nm or more and 100 μm or less;
containing,
A method for preparing a cosmetic composition composed of micro-nano capsules.

Images