KR102209353B1 - 파킨슨 병 치료 방법 - Google Patents

파킨슨 병 치료 방법 Download PDF

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Publication number
KR102209353B1
KR102209353B1 KR1020157028984A KR20157028984A KR102209353B1 KR 102209353 B1 KR102209353 B1 KR 102209353B1 KR 1020157028984 A KR1020157028984 A KR 1020157028984A KR 20157028984 A KR20157028984 A KR 20157028984A KR 102209353 B1 KR102209353 B1 KR 102209353B1
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levodopa
carbidopa
administered
parkinson
arginine
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Korean (ko)
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KR20150131230A (ko
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오론 야코비-제에비
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뉴로덤 엘티디
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50513395&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR102209353(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Otolaryngology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020157028984A 2013-03-13 2014-03-13 파킨슨 병 치료 방법 Active KR102209353B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361779357P 2013-03-13 2013-03-13
US61/779,357 2013-03-13
PCT/IL2014/050261 WO2014141261A1 (en) 2013-03-13 2014-03-13 Method for treatment of parkinson's disease

Publications (2)

Publication Number Publication Date
KR20150131230A KR20150131230A (ko) 2015-11-24
KR102209353B1 true KR102209353B1 (ko) 2021-01-29

Family

ID=50513395

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157028984A Active KR102209353B1 (ko) 2013-03-13 2014-03-13 파킨슨 병 치료 방법

Country Status (21)

Country Link
US (4) US20160022573A1 (https=)
EP (2) EP3892266A1 (https=)
JP (2) JP6472391B2 (https=)
KR (1) KR102209353B1 (https=)
CN (2) CN105209029A (https=)
AU (1) AU2014229127B2 (https=)
BR (1) BR112015022390A8 (https=)
CA (1) CA2904838C (https=)
CL (1) CL2015002641A1 (https=)
DK (1) DK2968218T3 (https=)
ES (1) ES2889626T3 (https=)
HR (1) HRP20211442T1 (https=)
HU (1) HUE056006T2 (https=)
IL (1) IL266648B (https=)
MX (1) MX365206B (https=)
PL (1) PL2968218T3 (https=)
PT (1) PT2968218T (https=)
RU (2) RU2018144700A (https=)
SG (2) SG10201911731YA (https=)
WO (1) WO2014141261A1 (https=)
ZA (1) ZA201507621B (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010134074A1 (en) 2009-05-19 2010-11-25 Neuroderm Ltd Compositions for continuous administration of dopa decarboxylase inhibitors
EP2640358B1 (en) 2010-11-15 2018-01-03 Neuroderm Ltd Continuous administration of l-dopa, dopa decarboxylase inhibitors, catechol-o-methyl transferase inhibitors and compositions for same
EP2640370B1 (en) 2010-11-15 2018-03-14 Neuroderm Ltd Compositions for transdermal delivery of active agents
ES2967693T3 (es) * 2014-03-13 2024-05-03 Neuroderm Ltd Composiciones del inhibidor de la dopa descarboxilasa
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
PT3782617T (pt) 2014-09-04 2024-02-29 Lobsor Pharmaceuticals Ab Composições farmacêuticas de gel compreendendo levodopa, carbidopa e entacapona
RU2743347C2 (ru) 2014-10-21 2021-02-17 Эббви Инк. Пролекарства карбидопа и l-dopa и их применение для лечения болезни паркинсона
MA41377A (fr) 2015-01-20 2017-11-28 Abbvie Inc Gel intestinal de lévodopa et de carbidona et procédés d'utilisation
WO2017039525A1 (en) * 2015-09-04 2017-03-09 Lobsor Pharmaceuticals Aktiebolag Method of treating a dopamine related disorder in a subject by administering levodopa, in combination with a dopamine decarboxylase inhibitor and a catechol-o-methyltransferase inhibitor
WO2017070293A1 (en) * 2015-10-20 2017-04-27 Ironwood Pharmaceuticals, Inc. Phosphodiesterase 9 inhibitor and levodopa therapy
EP3275433A1 (en) * 2016-07-29 2018-01-31 Som Innovation Biotech S.L. Sustained release composition comprising micronized tolcapone
HUE054268T2 (hu) * 2017-06-05 2021-08-30 Dizlin Pharmaceuticals Ab Levodopa infúziós oldat
WO2019097120A1 (en) * 2017-11-16 2019-05-23 Orion Corporation New use and pharmaceutical dosage forms
CN111655243A (zh) 2018-01-29 2020-09-11 乔纳森·萨克纳-伯恩斯坦 在人类神经系统疾病中调节多巴胺的方法
EP3773532A4 (en) * 2018-03-29 2022-11-02 Avion Pharmaceuticals, LLC FRACTIONAL LEVODOPA DOSAGE AND USE
CN113015531A (zh) 2018-11-15 2021-06-22 艾伯维公司 用于皮下施用的药物调配物
CN111701024B (zh) * 2020-05-26 2022-05-24 上海京新生物医药有限公司 一种左旋多巴制剂及其制备方法及其应用
US20230181508A1 (en) * 2020-08-31 2023-06-15 Purdue Pharma L.P. Compositions and methods for levodopa delivery
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
WO2023282900A1 (en) * 2021-07-08 2023-01-12 Morehouse School Of Medicine Method and system of diagnosing and treating neurodegenerative disease and seizures
US12161612B2 (en) 2023-04-14 2024-12-10 Neuroderm, Ltd. Methods and compositions for reducing symptoms of Parkinson's disease

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100298428A1 (en) 2009-05-19 2010-11-25 Oron Yacoby-Zeevi Continuous Administration of Dopa Decarboxylase Inhibitors and Compositions for Same
WO2012066538A1 (en) 2010-11-15 2012-05-24 Neuroderm Ltd Continuous administration of l-dopa, dopa decarboxylase inhibitors, catechol-o-methyl transferase inhibitors and compositions for same

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US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US4832957A (en) * 1987-12-11 1989-05-23 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
FI109453B (fi) * 1999-06-30 2002-08-15 Orion Yhtymae Oyj Farmaseuttinen koostumus
EA013161B1 (ru) * 2005-06-08 2010-02-26 Орион Корпорейшн Дозированная форма для перорального применения
TR200806646A2 (tr) * 2008-09-03 2009-06-22 Dr. F. Fri̇k İlaç San. Ve Ti̇c. A.Ş. Entakapon, levodopa ve karbidoba içeren farmasötik kombinasyonlar

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100298428A1 (en) 2009-05-19 2010-11-25 Oron Yacoby-Zeevi Continuous Administration of Dopa Decarboxylase Inhibitors and Compositions for Same
WO2012066538A1 (en) 2010-11-15 2012-05-24 Neuroderm Ltd Continuous administration of l-dopa, dopa decarboxylase inhibitors, catechol-o-methyl transferase inhibitors and compositions for same

Non-Patent Citations (1)

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Title
European Journal of Neurology, 19(6), 820-826, 2012.

Also Published As

Publication number Publication date
RU2677278C2 (ru) 2019-01-16
HRP20211442T1 (hr) 2022-02-04
US20210093560A1 (en) 2021-04-01
IL266648B (en) 2020-08-31
JP6625773B2 (ja) 2019-12-25
US20230047847A1 (en) 2023-02-16
JP6472391B2 (ja) 2019-02-20
JP2016512230A (ja) 2016-04-25
JP2019070041A (ja) 2019-05-09
AU2014229127A1 (en) 2015-11-05
EP3892266A1 (en) 2021-10-13
RU2015143112A (ru) 2017-04-20
US20250177292A1 (en) 2025-06-05
CA2904838A1 (en) 2014-09-18
IL266648A (en) 2019-07-31
MX2015012561A (es) 2016-06-28
ES2889626T3 (es) 2022-01-12
AU2014229127B2 (en) 2018-04-05
KR20150131230A (ko) 2015-11-24
BR112015022390A8 (pt) 2019-11-26
PL2968218T3 (pl) 2022-01-10
MX365206B (es) 2019-05-27
DK2968218T3 (da) 2021-09-20
CN110935026A (zh) 2020-03-31
HUE056006T2 (hu) 2022-01-28
BR112015022390A2 (pt) 2017-07-18
ZA201507621B (en) 2019-04-24
EP2968218B1 (en) 2021-07-07
SG10201911731YA (en) 2020-02-27
RU2018144700A (ru) 2019-02-18
CA2904838C (en) 2021-03-16
WO2014141261A1 (en) 2014-09-18
CN105209029A (zh) 2015-12-30
SG11201507538UA (en) 2015-10-29
US20160022573A1 (en) 2016-01-28
EP2968218A1 (en) 2016-01-20
CL2015002641A1 (es) 2016-03-18
PT2968218T (pt) 2021-09-24

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