KR102151812B1 - Method for manufacturing functional beverage using extracts of chinese peashurb and beverage and food for the same - Google Patents

Abstract

Disclosed is a functional beverage and a manufacturing method using the extract of bone tobacco. The present invention comprises the steps of extracting the active ingredient of the bone damweed with a liquid extract of the bone damweed; Solubilization of the extract of the extract of the extract of the extract of the extract of the extract of the extract of the extract of the extract from the step of the step of adding 30 to 50 parts by weight of the extract of the extract of the extract of the extract with respect to 100 parts by weight of mineral water; Saccharifying the dilution of bone tobacco by mixing 300 g of glutinous rice based on 2L of the diluted solution of bone tobacco prepared through the water-soluble step; And heating and concentrating the saccharified saccharification solution to obtain a concentrated beverage stock solution; and a functional beverage containing the saccharification solution may be prepared.

Description

Functional beverage manufacturing method using bone tobacco extract and functional beverages and foods using bone tobacco extract produced by this manufacturing method {METHOD FOR MANUFACTURING FUNCTIONAL BEVERAGE USING EXTRACTS OF CHINESE PEASHURB AND BEVERAGE AND FOOD FOR THE SAME}

The present invention relates to a method for manufacturing a functional beverage using the extract of Osteopathic vinegar to prepare a functional beverage using the extract of Osteopathic vinegar, and to a functional beverage and food using the extract of the extract prepared by the method.

Recently, Korea has entered an aging society and the number of patients with arthritis is increasing as the elderly population increases. With industrialization and urbanization, exposure to hazardous substances or contact frequency is proportionally increasing. Contact with harmful substances including mental stress, heavy drinking, smoking, and viruses, for example, causes chronic diseases and degenerative diseases, and may appear as a syndrome. The number of patients with arthritis is increasing significantly in the younger generation. Men's sports activities, women's diet and childbirth, and intake of caffeine-rich beverages such as coffee and cola, which modern people often drink, appear to be one cause. Degenerative arthritis is the most common form of joint disease, and its prevalence tends to increase with age. On the other hand, the market for functional beverages using these specific active ingredients has been expanded and consumption has increased, with the focus on the fact that certain active ingredients of natural ingredients can be beneficially used for human disease prevention and treatment and health due to the improvement of living standards. Has become. On the other hand, joint diseases such as degenerative arthritis are currently the most common form of joint disease, but functional beverages or foods suitable for use remain in a state that is not properly made. As such, treatment of joint diseases is also important, but there is a need for a plan to overcome these diseases from foods that can be easily consumed and utilized such as general functional beverages.

For example, the active ingredient of the natural ingredient, bonedamcho, is partially used for the treatment of joint diseases and arthritis in oriental medicine and private sectors, but it is suggested to easily and conveniently consume or take the active ingredient of bonedamcho as a functional beverage and use it. Is insufficient. Looking at the use, use, and proposals related to the use of bone tobacco, Korean Patent Publication No. 10-2016-0135037'composition for the prevention or treatment of metabolic diseases containing the extract as an active ingredient', Korean Patent Publication No. 10-2017 It is disclosed as a'composition for inhibiting angiogenesis using an extract of Goldamcho' in No. -0073318,'a method of manufacturing a beverage-type health supplement' in Korean Patent Publication No. 10-2003-0066539. Accordingly, the inventor of the present applicant proposes to easily and conveniently consume or take the active ingredient of bone damchoe, which is effective for degenerative joints and joint diseases, as a functional beverage, and utilize it.

Patent Document 1. Korean Patent Application Publication 10-2016-0135037 (published on November 24, 2016)

Patent Document 2. Korean Patent Publication 10-2017-0073318 (published on June 28, 2017)

Patent Document 3. Korean Patent Publication 10-2003-0066539 (published on August 09, 2003)

One of the technical problems to be solved in the present invention is to effectively extract the active ingredient of the bone damweed.

One of the technical problems to be solved in the present invention is to prepare a functional beverage by mixing the active ingredient extracted from bone damchoe with other heterogeneous ingredients.

One of the technical problems to be solved in the present invention is to provide a functional beverage containing the active ingredient of bone damcho.

The above objects, according to the present invention, the step of extracting the active ingredient of the bone damweed extract with a liquid extract of the bone; Solubilization of the extract of the extract of the extract of the extract of the extract of the extract of the extract of the extract of the extract from the step of the step of adding 30 to 50 parts by weight of the extract of the extract of the extract of the extract with respect to 100 parts by weight of mineral water; Saccharifying the dilution of bone tobacco by mixing 300 g of glutinous rice based on 2L of the diluted solution of bone tobacco prepared through the water-soluble step; And heating and concentrating the saccharified solution of the saccharification step to obtain a concentrated beverage stock solution.

The above objects, according to the present invention, the step of extracting the active ingredient of the bone damweed extract with a liquid extract of the bone; Solubilization of the extract of the extract of the extract of the extract of the extract of the extract of the extract of the extract of the extract from the step of the step of adding 30 to 50 parts by weight of the extract of the extract of the extract of the extract with respect to 100 parts by weight of mineral water; Saccharifying the dilution of bone tobacco by mixing 300 g of glutinous rice based on 2L of the diluted solution of bone tobacco prepared through the water-soluble step; And 70 to 85% by weight of the saccharified solution of bone tobacco, which has been subjected to the saccharification step, 10 to 20% by weight of silver mushroom porridge, and 5 to 10% by weight of sweetener, while heating and concentrating for 15 to 20 minutes while stirring. Obtaining a; can be achieved from a method for producing a functional beverage using the extract, including, bone bile.

According to an exemplary embodiment of the present invention, the extract of bone tobacco can be stably obtained from the hot water extraction method.

According to an embodiment of the present invention, the sweetener may be one or more selected from white sugar, fructose, and oligosaccharide.

According to an embodiment of the present invention, in the saccharification step, after adding 2L of a diluent of golddam vinegar and 100 g of malt powder tea bags to 300 g of glutinous rice, saccharifying for 6 to 7 hours at a rice cooker temperature of 55 to 65°C, and recovering the tea bag after the saccharification is completed is further performed. Can include.

According to an embodiment of the present invention, silver-i mushroom porridge may be prepared by using powdered silver-i mushroom, adding water 4-6 times the weight of silver-i mushroom powder and heating.

According to an embodiment of the present invention, it is possible to obtain a functional beverage or food from a method for manufacturing a functional beverage using the extract of Osteopathic vinegar.

The present invention can be effectively used for the prevention and treatment of arthritis by making the active ingredient of bone damweed effective in the prevention and treatment of a wide range of joint diseases, including degenerative joints and arthritis, etc., as a functional beverage, so that anyone can easily and conveniently consume or take it. There is an effect.

1 is an example of the Naringenin content of the extract of Osmium sheath according to an embodiment of the present invention.
2 is an illustration of a calibration curve of Naringenin by LC-MS / MS analysis according to an embodiment of the present invention.
3 is an illustration of a typical chromatogram of Naringenin of a standard solution and a test solution by HPLC analysis according to an embodiment of the present invention.
4 is an example of arthritis classification criteria.
5 is an illustration of the total Mankin score according to an embodiment of the present invention.
6 is an example of mankin score evaluation score for each individual according to an embodiment of the present invention.
7 is an example of classification according to the Mankin score according to an embodiment of the present invention.
8 is an example of a serum biochemical test result according to an embodiment of the present invention.
9 is an example of a weight measurement result according to an embodiment of the present invention.

Hereinafter, referring to the accompanying drawings, a detailed description will be given of a'method for producing a functional beverage using an extract of bone damweed' according to a preferred embodiment of the present invention.

Among the terms or active ingredients used in the present invention,'Goldamcho (Caragana sinica)' is a deciduous shrub belonging to the leguminous family (Fabaceae) and is wild in all parts of Korea and parts of China such as Jeonbuk, Gyeongnam, Chungnam, and Gyeonggi, and is used in spring and autumn. The collected roots are dried in the sun and used as beverages. Goldamcho (骨痰草), meaning paste to attach bones, is derived from what has been used for bone-related diseases from ancient times and has been used as a treatment for neuralgia, bone medicine, arthritis, fractures, and neuralgia. Although it is used in oriental medicine and in the private sector, there are insufficient proposals for the manufacture and efficacy of a drink containing anti-inflammatory properties.

'White-throated mushroom' is also called'Eun-i mushroom (hereinafter referred to as'Eun-i mushroom')' and is a white wood-ear mushroom. In Donguibogam, Euni mushrooms are said to have good properties and sweet taste, and have the effect of enhancing energy. Silver ear mushrooms contain vitamins B1, B2, D and niacin, mannitol, glycerol, glucose, chitin, lignin hemicellulose, and pectin. Vitamin D content is contained about 20 times that of dried shiitake mushrooms, so it can be classified as a food that helps modern people's bone health as well as children in their growing age, and helps prevent immunity and aging. In the present invention, silver-i mushroom can be classified as a functional food supplementing functional nutrients excluded from the active ingredient of bone damcho.

Looking at the existing research cases and patent literature on anti-inflammatory in relation to the present invention, studies on detoxification of purslane, anti-edema, anti-aging, antioxidant, anti-inflammatory, anti-obesity, etc., antioxidant and anti-inflammatory effects of perilla sprouts, Antioxidant and inflammatory mediator control effects, comparison of antioxidant and anti-inflammatory activities of chestnut flesh bark and chestnut leaf extract, and comparative studies of antioxidant, anti-inflammatory and hepatoprotective effects of steamed Schisandra chinensis have been reported.

Anti-inflammatory related patent documents include anti-oxidation, anti-inflammatory and skin rejuvenation composition tricine 4′-O-(threo-β-guaiacyl glyceryl) ether containing Eoseongcho extract as an active ingredient. The composition for anti-inflammatory or moisturizing composition containing the extract of gold and silver, yugeun blood, and the mixture for killing, the anti-inflammatory composition using the seaweed extract, the anti-inflammatory composition using the oyster shell extract, the anti-inflammatory or osteoarthritis inhibitory effect using the oyster shell A method of separating a fraction having a fraction and the like is disclosed.

In the present invention, after extracting the extract of bone tobacco in an optimized and efficient manner and preparing it as a beverage, it is possible to find out the efficacy of bone tobacco using a monosodium iodoacetate (MIA) administration model, which is a representative degenerative arthritis animal model, to meet the tastes of modern people. By making it easy to use as a beverage, we propose a functional beverage and a manufacturing method using a new osteocide extract that can be effectively utilized in the prevention and treatment of arthritis.

It will be described in relation to the extraction of the active ingredient of bone damcho according to a preferred embodiment of the present invention as follows.

A method for producing a functional beverage using the extract of Osmella according to a preferred embodiment of the present invention will be described in sequence as follows.

Example 1

Extracting the active ingredient of the bone tobacco with a liquid extract of the extract, the extract of the extract extracted from the above step with 30 to 50 parts by weight of the extracted extract of the extract with respect to 100 parts by weight of bottled water, and a water-soluble step of the extract of the extract of the bone tobacco; Saccharifying the dilution of bone tobacco by mixing 300 g of glutinous rice based on 2L of the diluted solution of bone tobacco prepared through the water-soluble step; And it is possible to prepare a functional beverage from the step of obtaining a concentrated beverage stock solution by heating and concentrating the saccharified solution of bone tobacco that has undergone the saccharification step.

Example 2

Extracting the active ingredient of the bone tobacco with a liquid extract of the extract; Solubilization of the extract of the extract of the extract of the extract of the extract of the extract of the extract of the extract of the extract from the step of the step of adding 30 to 50 parts by weight of the extract of the extract of the extract of the extract with respect to 100 parts by weight of mineral water; Saccharifying the dilution of bone tobacco by mixing 300 g of glutinous rice based on 2L of the diluted solution of bone tobacco prepared through the water-soluble step; And 70 to 85% by weight of the saccharified solution of bone tobacco, which has been subjected to the saccharification step, 10 to 20% by weight of silver mushroom porridge, and 5 to 10% by weight of sweetener, while heating and concentrating for 15 to 20 minutes while stirring. Functional beverages can be prepared from the step of obtaining.

It will be described in relation to the extraction of the active ingredient of bone damcho according to a preferred embodiment of the present invention as follows.

Extraction of active ingredients of bone damweed (Goldamcho extract)

The active ingredient of bone tobacco may be extracted with a liquid extract of bone tobacco. Two extraction methods are presented as follows. The two extraction methods may be hot water extraction and pressure extraction.

1) Hot water extraction method

After washing the roots, leaves, and stems of the bonito, crush them finely (crushing step).

Add water 10-15 times the weight of Goldamcho to the crushed Goldamcho in a traditional pottery, and heat at 70℃ for 6-7 hours (heating step).

A cotton cloth is placed on a 25 mesh sieve and debris is removed to obtain an extract of bone damweed (extraction step).

2) Pressurized extraction method

After washing the roots, leaves, and stems of the bonito, crush them finely (crushing step).

After adding water 5-7 times the weight of the crushed bone damweed, it is heated for 4 hours at a pressure of 2 atm (heating step).

A cotton cloth is placed on a 25 mesh sieve and debris is removed to obtain an extract of bone damweed (extraction step).

According to the functional component analysis results of the extracts of the extracts of osteoclasts extracted by different extraction methods as described above, in common in any case, the unique active ingredient of the extracts of the extracts of osteocide can be obtained as a liquid extracts of the extracts of osteoclasts by water added during the extraction process.

Hot water extraction method may be selected as a preferred extraction method because the preservation of the inherent active ingredient of the bone damweed extracted by the hot water extraction method is good, and the content of the active ingredient may be higher than that of the pressure extraction method.

Therefore, the bone tobacco extract was analyzed through functional component analysis of the extract prepared by the hot water extraction method and the pressurized extraction method (Naringenin, a non-sugar-free flavanone, among them) It may be desirable to prepare the beverage using. The experimental results are as follows.

In this experiment result 1, the Naringenin content of the extract of the extract prepared by the hot water extraction method and the pressurized extraction method, which is currently the most widely used, was analyzed in order to find an efficient extraction method of bone damweed, and it was carried out based on the analysis method verification SOP.

Experiment result 1

The content of Naringenin, a kind of flavonoids analyzed in the two types of bone tobacco extract extracted from the hot water extraction method and the pressurized extraction method, contains 0.0577 mg per liter of the extract of the bone tobacco extract of the hot water extraction method, which is 151% compared to the extract of the pressure extraction method. It was confirmed that Naringenin of was contained. This is the same as the accompanying drawings 1 to 3.

1 is an example of the Naringenin content of the extract of Osmium sheath according to an embodiment of the present invention. 2 is an illustration of a calibration curve of Naringenin by LC-MS / MS analysis according to an embodiment of the present invention. 3 is an illustration of a typical chromatogram of Naringenin of a standard solution and a test solution by HPLC analysis according to an embodiment of the present invention.

Therefore, in the present invention, a preferred extraction method in the extraction of the active ingredient of the bone damweed may be selected from the heat extraction method.

A method of manufacturing a functional beverage using the extract of Osmella according to a preferred embodiment of the present invention will be described below.

Example 3( Golddamweed Preparation of beverages using extract)

1) Pre-treatment step

After washing the glutinous rice, add 0.9 to 1.0 times the weight of the glutinous rice and cook the rice in a pressure cooker. Silver-i mushrooms use powdered silver-i mushrooms, add water 4-6 times the weight of silver-i mushrooms, and heat to make porridge.

2) Soluble step

To 100 parts by weight of mineral water, 30 to 50 parts by weight of the extract of the extract of Goldamcho extracted by the hot water extraction method are added to make a dilute solution of Goldamcho.

3) saccharification step

In 300g of glutinous rice, add 2L of the diluent of Goldamcho and 100g of malt powder, then saccharify for 6-7 hours in an electric rice cooker at 60℃. When saccharification is complete, remove the teabag and rice grains.

4) Concentration step

Mix in a composition ratio of 70 to 85% by weight of the saccharification solution of bone tobacco, 10 to 20% by weight of silver mushroom porridge, and 5 to 10% by weight of sweetener (white sugar, fructose, oligosaccharide), stir to prevent burning, and heat and concentrate for 15 to 20 minutes. A concentrated beverage stock solution is obtained.

5) Storage processing and drinking

The concentrated beverage stock solution thus obtained is stored in a sealed container and stored in a refrigerator, and when drinking, it may be desirable to mix and dilute 4 to 6 times in cold and hot water to drink.

Using the Monosodium iodoacetate (MIA) administration model for the extract of bone tobacco concentrate prepared by the above method or the beverage using the extract of bone tobacco extract, through an efficacy test, it was confirmed whether it can be used as a functional beverage such as the functionality of bone tobacco and the effect of preventing arthritis. Confirmed. The functional analysis results are as follows.

Analysis results of functional components of bone tobacco extract

In the extract of bone tobacco, there is Naringenin, a flavonone-free sugar, which is a kind of flavonoid, and flavonoids have been shown to have biological and pharmacological activities, and have anti-allergic, anti-inflammatory, antioxidant, antimicrobial, antifungal, and antiviral activities.

Naringenin inhibits lipidization by limiting the accumulation of neutral lipids in the endoplasmic reticulum, helps repair damaged DNA in cancer cells, and may have anticancer effects that inhibit the initiation of the carcinogenesis process.

As it plays a role in helping T-immune regulatory cells, it has been confirmed that it can act to prevent both immune-lowering and autoimmune diseases. The results of the test for confirming the efficacy of the Beverage Beverage are as follows.

Monosodium Administration of iodoacetate (MIA) Model used Golddamweed Beverage efficacy test

1) Experiment method

In the efficacy confirmation test of the bone tobacco drink, a drink prepared according to Example 3 using a hot water extraction method containing a large amount of Naringenin was selected and tested for efficacy.

The efficacy of the bone tobacco drink was confirmed using a monosodium iodoacetate (MIA) administration model, a representative degenerative arthritis animal model. When MIA is administered into the joint cavity, it inhibits the glycolysis of chondrocytes, which are cells that form cartilage, thereby killing chondrocytes and eventually destroying cartilage. It is known that the changes in joint tissue appearing in the animal model of degenerative arthritis using MIA are very similar to the histological changes in human arthritis.

After administration of MIA prepared at a concentration of 40 mg/ml in sterile physiological saline in the joint cavity of the rat, the bone tobacco drink was forcibly orally administered once a day for 3 weeks. At this time, the dosage volume is 10 ml/kg bw for the high-dose group. In the case of the low-dose administration group, 5 ml/kg bw. was administered, and as a positive control drug for confirming the reliability of the test, Ibuprofen 20 mg/kg bw. was administered at the same intervals and methods. After the end of the 3-week administration period, blood and joint tissue were collected by autopsy.

After CO2 anesthesia, blood was collected from the abdominal aorta by laparotomy and centrifugation at 3000 rpm for 10 minutes to obtain serum. The obtained serum was analyzed for AST and ALT as hepatotoxicity indicators using an automatic biochemical analyzer hitachi 7020 (hitachi, tokyo, japan), and BUN and Creatinine as kidney toxicity indicators.

After blood loss, the knee joint was excised and fixed in 10% neutral buffered formalin for 2 days. After that, a paraffin block was produced through a general tissue treatment process after demineralization in 5% formic acid for 48 hours. After cutting to a thickness of 5 μm, H&E stain and Safranin O stain were performed and observed with an optical microscope (Olympus BX51, Olympus Co., Ltd, USA), and the degree of damage was scored according to the arthritis classification criteria as shown in FIG. 4. The results were derived based on the scored results. Tissue readout was performed based on partially changed Mankin score, and the total score was 14 points.

By observing the slides stained with H&E, structural changes of cartilage were classified on a 6-point scale, and the degree of death of chondrocytes was used on a 3-point scale. In addition, 1 additional point was given according to the presence or absence of tidemark damage. The cartilage tissue staining method, Safranin O stained slides were observed and classified on a 4-point scale according to the staining intensity (refer to the arthritis classification criteria in FIG. 4).

4 is an example of arthritis classification criteria. 5 is an illustration of the total Mankin score according to an embodiment of the present invention.

Based on the total Mankin score of FIG. 5, 02 points were determined as normal cartilage, 35 points were superficial fibrillation, 67 points were moderately cartilage destruction, 810 points were severely damage of cartilage, and if it exceeded 10, it was determined as complete loss of cartilage.

2) Experiment result

5 is an illustration of the total Mankin score according to an embodiment of the present invention. 6 is an example of mankin score evaluation score for each individual according to an embodiment of the present invention. 7 is an example of classification according to the Mankin score according to an embodiment of the present invention.

As shown in FIGS. 5 to 7, the total Mankin score result was as in FIG. 5, and the individual Markin score as a detailed evaluation result was as in FIG. 6. The result of classifying the grade based on the evaluated score was shown in FIG. 7.

These results can be seen to mean that the progression of degenerative arthritis was suppressed by suppressing the death of cartilage cells, preventing damage to the cartilage structure, and suppressing the loss of the cartilage matrix.

8 is an example of a serum biochemical test result according to an embodiment of the present invention. 9 is an example of a weight measurement result according to an embodiment of the present invention.

In the serum biochemical test result as shown in FIG. 8 performed to confirm the safety of the bone tobacco drink, no significant difference was found between the test groups, and the weight measurement result as shown in FIG. 9 also showed no significant difference compared to the MIA group. Did. These results can be seen to mean that no apparent toxicity was observed when the extract of Osmella was administered orally for 3 weeks.

As described above, the present invention contains, as an active ingredient, Naringenin, which is a flavonone-free, which is a kind of flavonoids contained in the extract of Osmanthus, when a functional beverage is prepared using the extract of Osteopathic extract. It was found to have functions such as anti-allergic, anti-inflammatory, antioxidant, anti-microbial, anti-fungal, and anti-viral activity, and other additives including silver ear mushrooms function as additives to enhance or supplement nutrients and to satisfy palatability. It may not have a significant meaning in the component analysis target.

On the other hand, as confirmed from test result 1.2, Naringenin in the extract of Osteopathic ginseng suppresses lipidization by limiting the accumulation of neutral lipids in the endoplasmic reticulum, helps repair damaged DNA in cancer cells, and has anti-cancer effects that inhibit the initiation of the carcinogenesis process. As it plays a role in helping T-immune regulatory cells, it has been confirmed that it can act to prevent both immune deterioration and autoimmune diseases.The active ingredient of bone tobacco is consumed as a beverage or ingested as a beverage after a certain treatment process. It is effective in anti-inflammatory, including diseases, so it can be sufficiently utilized for prevention and treatment purposes.

As described above, the present invention provides a scientific analysis of the functional components of the extract of Osteopathica to find an extraction method capable of effectively extracting the active ingredient contained in the extract of Osteopathia in order to obtain an optimized extraction method by comparatively comparing the hot water extraction method and the pressurized extraction method. By analyzing and identifying as a liquid extract, it is possible to effectively extract the active ingredient of bone damweed that can be consumed as a beverage or as a food.

In addition, it is possible to systematically and scientifically manufacture functional beverages by using the extract of bone tobacco, and by effectively extracting the extract of bone tobacco and adding additives such as silver mushroom porridge and sweetener to the extract, it is possible to effectively prepare a functional beverage stock solution.

In addition, glutinous rice can be added to the extract of Goldamcho and saccharified, and then heated and concentrated by mixing silver mushroom porridge and sweetener to obtain a concentrated juice solution. It can be improved, and it can be widely used as a beverage suitable for modern people's taste by diluting an appropriate amount of the concentrated extract of a drink of bonedam chop in water.

In addition, since the concentrated undiluted solution can be prepared by adding silver-i mushroom porridge and a sweetener to the goldamcho, it is possible to improve the beverage palatability and storage properties for the active ingredients of the goldamcho.

In addition, by analyzing the functional components and efficacy of the Beverages containing the effective ingredients of B. B. B., it can be effectively used for the prevention and treatment of arthritis, thereby increasing the possibility of using B. B. and the use and utilization of the B. You can make it possible.

The present invention has been described with reference to the embodiments shown in the drawings, but is not limited to the embodiments, and can be carried out with modifications and variations without departing from the gist of the present invention, and modifications and variations are made in the spirit of the present invention. Included.

Claims (8)

delete (A) extracting the active ingredient of the bone tobacco with a liquid extract of the extract;
(B) the step (A) of the extract of the extract of the extract of the extract of the extract of the extract of the extract with respect to 100 parts by weight of bottled water, 30 to 50 parts by weight of the extract of the extract is made a dilute solution;
(C) mixing 300 g of glutinous rice based on 2L of the diluent of bone tobacco prepared through the solubilization step to saccharify the diluted solution of bone tobacco;
(D) After the saccharification step, the saccharification solution is 70 to 85% by weight, 10 to 20% by weight of silver mushroom porridge, and 5 to 10% by weight of sweetener are mixed and stirred, heated for 15 to 20 minutes, concentrated and concentrated. Including; obtaining a drink stock solution;
The bone tobacco extract is obtained by a hot water extraction method, the hot water extraction method,
After washing and crushing the roots, leaves, and stems,
Putting 10-15 times of the weight of the Goldamcho in the crushed Goldamcho in an Onggi and heating at 70℃ for 6-7 hours,
It consists of a step of obtaining a bone wall vinegar extract by placing a cotton cloth on a 25 mesh sieve and removing debris,
In addition, the step (C) is a step of saccharifying at 55 to 65° C. for 6 to 7 hours after adding 2 L of a diluent of bone damweed and 100 g of malt powder tea bag to 300 g of glutinous rice,
In addition, the silver-i mushroom porridge, using powdered silver-i mushrooms, a method for producing a functional beverage using a bone tobacco extract, characterized in that prepared by heating and adding water 4-6 times the weight of the silver-i mushroom powder. delete The method of claim 2,
The sweetener is one or more selected from white sugar, fructose, and oligosaccharide. delete delete A functional beverage using the extract of the bone damweed prepared by the manufacturing method of any one of claims 2 and 4. A functional food using the extract of bone damweed prepared by the manufacturing method of any one of claims 2 and 4.

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