KR102134585B1 - 보조 암 치료 방법 - Google Patents

보조 암 치료 방법 Download PDF

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Publication number
KR102134585B1
KR102134585B1 KR1020157008387A KR20157008387A KR102134585B1 KR 102134585 B1 KR102134585 B1 KR 102134585B1 KR 1020157008387 A KR1020157008387 A KR 1020157008387A KR 20157008387 A KR20157008387 A KR 20157008387A KR 102134585 B1 KR102134585 B1 KR 102134585B1
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KR
South Korea
Prior art keywords
melanoma
dabrafenib
trametinib
pharmaceutical composition
patient
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KR1020157008387A
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English (en)
Korean (ko)
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KR20150047619A (ko
Inventor
실비 라퀴레
피터 에프. 레보비츠
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노바르티스 아게
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50237545&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR102134585(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 노바르티스 아게 filed Critical 노바르티스 아게
Publication of KR20150047619A publication Critical patent/KR20150047619A/ko
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Publication of KR102134585B1 publication Critical patent/KR102134585B1/ko
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
KR1020157008387A 2012-09-04 2013-08-30 보조 암 치료 방법 Active KR102134585B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261696375P 2012-09-04 2012-09-04
US61/696,375 2012-09-04
PCT/US2013/057432 WO2014039375A1 (en) 2012-09-04 2013-08-30 Method of adjuvant cancer treatment

Publications (2)

Publication Number Publication Date
KR20150047619A KR20150047619A (ko) 2015-05-04
KR102134585B1 true KR102134585B1 (ko) 2020-07-17

Family

ID=50237545

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157008387A Active KR102134585B1 (ko) 2012-09-04 2013-08-30 보조 암 치료 방법

Country Status (20)

Country Link
US (6) US20150216868A1 (enExample)
EP (2) EP2892535B1 (enExample)
JP (3) JP2015527374A (enExample)
KR (1) KR102134585B1 (enExample)
CN (2) CN107308164A (enExample)
AU (2) AU2013313050A1 (enExample)
BR (1) BR112015004578A2 (enExample)
CA (1) CA2882437C (enExample)
CY (1) CY1124812T1 (enExample)
DK (1) DK2892535T3 (enExample)
ES (1) ES2900825T3 (enExample)
HR (1) HRP20211817T1 (enExample)
HU (1) HUE056646T2 (enExample)
IN (1) IN2015KN00449A (enExample)
LT (1) LT2892535T (enExample)
PL (1) PL2892535T3 (enExample)
PT (1) PT2892535T (enExample)
RU (1) RU2640180C2 (enExample)
SI (1) SI2892535T1 (enExample)
WO (1) WO2014039375A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2892535T (pt) 2012-09-04 2021-12-15 Novartis Ag Método de tratamento adjuvante do cancro
SG11201604923XA (en) 2013-12-28 2016-07-28 Guardant Health Inc Methods and systems for detecting genetic variants
EP3515446B1 (en) 2016-09-19 2023-12-20 Novartis AG Therapeutic combinations comprising a raf inhibitor and a erk inhibitor
CN110494166B (zh) 2017-05-02 2022-11-08 诺华股份有限公司 组合疗法
WO2019204399A1 (en) * 2018-04-17 2019-10-24 The University Of Chicago Methods and compositions for treating cancer
CN109106893B (zh) * 2018-11-12 2021-04-20 上海市中西医结合医院 一种调节肠道屏障功能的中药复方制剂及其制备方法
KR102881316B1 (ko) 2019-05-13 2025-11-05 노파르티스 아게 암 치료를 위한 raf 억제제로서의 n-(3-(2-(2-하이드록시에톡시)-6-모르폴리노피리딘-4-일)-4-메틸페닐)-2 (트리플루오로메틸)이소니코틴아미드의 새로운 결정질 형태
WO2021118924A2 (en) * 2019-12-12 2021-06-17 Ting Therapeutics Llc Compositions and methods for the prevention and treatment of hearing loss
EP4444299A1 (en) 2021-12-06 2024-10-16 My Personal Therapeutics Ltd A combination treatment for cancer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011047238A1 (en) * 2009-10-16 2011-04-21 Glaxosmithkline Llc Combination

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1761528T3 (pl) * 2004-06-11 2008-05-30 Japan Tobacco Inc Pochodne 5-amino-2,4,7-triokso-3,4,7,8-tetrahydro-2H-pirydo[2,3-D]pirymidyny i związki pokrewne do leczenia raka
HUE038768T2 (hu) * 2005-02-18 2018-11-28 Abraxis Bioscience Llc Terápiás szerek kombinációi, valamint beadásukra szolgáló módszerek, és kombinációs terápia
UA103319C2 (en) 2008-05-06 2013-10-10 Глаксосмитклайн Ллк Thiazole- and oxazole-benzene sulfonamide compounds
US20130004481A1 (en) * 2011-01-12 2013-01-03 Boehringer Ingelheim International Gmbh Anticancer therapy
PT2892535T (pt) 2012-09-04 2021-12-15 Novartis Ag Método de tratamento adjuvante do cancro

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011047238A1 (en) * 2009-10-16 2011-04-21 Glaxosmithkline Llc Combination

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Journal of Translational Medicine (Published: 2012. 5 .3)*

Also Published As

Publication number Publication date
DK2892535T3 (da) 2022-01-03
SI2892535T1 (sl) 2022-01-31
AU2016244279A1 (en) 2016-11-03
US20210060021A1 (en) 2021-03-04
PL2892535T3 (pl) 2022-01-31
CY1124812T1 (el) 2022-11-25
CA2882437A1 (en) 2014-03-13
US20200054641A1 (en) 2020-02-20
HRP20211817T1 (hr) 2022-03-04
US10869869B2 (en) 2020-12-22
US20170202842A1 (en) 2017-07-20
JP6511117B2 (ja) 2019-05-15
CN107308164A (zh) 2017-11-03
EP2892535A4 (en) 2016-04-13
IN2015KN00449A (enExample) 2015-07-17
US20180338979A1 (en) 2018-11-29
JP2015527374A (ja) 2015-09-17
AU2016244279B2 (en) 2018-01-04
LT2892535T (lt) 2021-12-10
RU2015105821A (ru) 2016-10-20
US20230330091A1 (en) 2023-10-19
HUE056646T2 (hu) 2022-02-28
HK1206642A1 (en) 2016-01-15
RU2640180C2 (ru) 2017-12-26
BR112015004578A2 (pt) 2017-07-04
CN104582706A (zh) 2015-04-29
WO2014039375A1 (en) 2014-03-13
JP2018058859A (ja) 2018-04-12
ES2900825T3 (es) 2022-03-18
EP2892535B1 (en) 2021-09-22
KR20150047619A (ko) 2015-05-04
US20150216868A1 (en) 2015-08-06
CA2882437C (en) 2021-03-02
EP2892535A1 (en) 2015-07-15
AU2013313050A1 (en) 2015-03-26
JP6684941B2 (ja) 2020-04-22
JP2019142899A (ja) 2019-08-29
PT2892535T (pt) 2021-12-15
EP3981408A1 (en) 2022-04-13

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